@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1628: (2015-12-09 )
MTMLKVENLSIHYGVIQAVNDVSFEVNQGEVVTLIGANGTGKTSILRTISGLVRPSQGSISFMGKPIHKLAARKIVGNGLAQVPEGRHVFSSLSVMENLEMGAFLQKDREQNQKMLKKVFDRFPRLEERKNQDAATLSGGEQQMLAMGRALMSRPKLLLLDEPSMGLAPIFIQEIFNIIEDIKKQGTTVLLVEQNANKALTIADKAYVLETGKVVLSGTGKELLVSDQVRKAYLGG
Atome Classification :
(20 SA)
.........10...-----.....20........30........40........50........60...-----.-----...--.70-........80........90........100-.-----------....----------.----.---110......---------.-120-....--....130.......140.......150.......160.......170.......180.-.-.....190.......200.......210.......220----...----....--230....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
T
M
L
K
V
EN
L
S
I
H
Y
G
-----
V
I
Q
A
VN
D
V
S
F
E
VNQG
E
V
V
T
L
I
GANGT
G
K
T
S
I
L
R
T
I
S
G
LVRPSQG
S
I
SFMG-----
K
-----
P
I
H
--
K
L
A
-
A
R
K
I
V
GN
G
L
AQVPE
G
R
H
V
F
S
S
L
S
V
M
E
NL
E
M
G
-
A
-----------
F
L
Q
K
----------
D
----
R
---
E
Q
N
Q
K
M
L
K
K
---------
V
-
F
D
--RFP
R
--
L
E
E
R
KNQDAATLSG
G
E
Q
Q
M
L
A
M
G
R
A
L
MSRP
K
L
L
L
L
DEPSMG
L
A
P
I
F
I
Q
E
I
F
N
I
I
E
D
I
K
-K-QG
T
T
V
L
L
V
EQNAN
K
A
L
T
IAD
K
A
Y
V
L
ET
G
K
V
V
L
SGTGK
E
----
L
L
V
----
S
D
Q
V
--
R
K
A
YLGG
46
HHSearch
91.97
55%
-108
- C1 -
1JI0
1
?
A:
[5-237]
-
I
V
L
E
V
Q
S
L
H
V
Y
Y
G
-----
A
I
H
A
I
K
G
I
D
L
K
V
P
R
G
Q
I
V
T
L
I
G
A
N
G
A
G
K
T
T
T
L
S
A
I
A
G
L
V
R
A
Q
K
G
K
I
I
F
N
G
-----
Q
-----
D
I
T
--
N
K
P
-
A
H
V
I
N
R
M
G
I
A
L
V
P
E
G
R
R
I
F
P
E
L
T
V
Y
E
N
L
M
M
G
-
A
-----------
Y
N
R
K
----------
D
----
K
---
E
G
I
K
R
D
L
E
W
---------
I
-
F
S
--
L
F
P
R
--
L
K
E
R
L
K
Q
L
G
G
T
L
S
G
G
E
Q
Q
M
L
A
I
G
R
A
L
M
S
R
P
K
L
L
M
M
D
E
P
S
L
G
L
A
P
I
L
V
S
E
V
F
E
V
I
Q
K
I
N
-
Q
-
E
G
T
T
I
L
L
V
E
Q
N
A
L
G
A
L
K
V
A
H
Y
G
Y
V
L
E
T
G
Q
I
V
L
E
G
K
A
S
E
----
L
L
D
----
N
E
M
V
--
R
K
A
Y
L
G
V
1
PsiBlast_PDB
90.39
53%
-109
- C1 -
1JI0
1
?
A:
[6-238]
--
V
L
E
V
Q
S
L
H
V
Y
Y
G
-----
A
I
H
A
I
K
G
I
D
L
K
V
P
R
G
Q
I
V
T
L
I
G
A
N
G
A
G
K
T
T
T
L
S
A
I
A
G
L
V
R
A
Q
K
G
K
I
I
F
N
G
-----
Q
-----
D
I
T
--
N
K
P
-
A
H
V
I
N
R
M
G
I
A
L
V
P
E
G
R
R
I
F
P
E
L
T
V
Y
E
N
L
M
M
G
-
A
-----------
Y
N
R
K
----------
D
----
K
---
E
G
I
K
R
D
L
E
W
---------
I
-
F
S
--
L
F
P
R
--
L
K
E
R
L
K
Q
L
G
G
T
L
S
G
G
E
Q
Q
M
L
A
I
G
R
A
L
M
S
R
P
K
L
L
M
M
D
E
P
S
L
G
L
A
P
I
L
V
S
E
V
F
E
V
I
Q
K
I
N
-
Q
-
E
G
T
T
I
L
L
V
E
Q
N
A
L
G
A
L
K
V
A
H
Y
G
Y
V
L
E
T
G
Q
I
V
L
E
G
K
A
S
E
----
L
L
D
----
N
E
M
V
--
R
K
A
Y
L
G
V
8
PsiBlast_PDB
83.55
33%
-100
- C1 -
4P32
2
LPTB_ECOLI
A:
[3-234]
---
L
T
A
K
N
L
A
K
A
Y
K
-----
G
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
-----
D
DISLL
P
L
H
--
A
R
A
-
R
R
-----
G
I
G
Y
L
P
Q
E
A
S
I
F
R
R
L
S
V
Y
D
N
L
-
M
A
-
V
-----------
L
Q
I
R
----------
D
----
D
LS
A
E
Q
R
E
D
R
A
N
E
---------
L
-
M
E
--
E
F
-
H
--
I
E
H
L
R
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
-
D
-
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
----
I
L
Q
----
D
E
H
V
--
K
R
V
Y
L
--
6
PsiBlast_PDB
81.84
33%
-100
- C1 -
4QC2
2
?
A:
[2-236]
-
A
T
L
T
A
K
N
L
A
K
A
Y
K
-----
G
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
-----
D
DISLL
P
L
H
--
A
R
A
-
R
R
-----
G
I
G
Y
L
P
Q
E
A
S
I
F
R
R
L
S
V
Y
D
N
L
-
M
A
-
V
-----------
L
Q
I
R
----------
D
----
D
LS
A
E
Q
R
E
D
R
A
N
E
---------
L
-
M
E
--
E
F
-
H
--
I
E
H
L
R
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
-
D
-
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
----
I
L
Q
----
D
E
H
V
--
K
R
V
Y
L
G
-
23
PsiBlast_CBE
81.50
33%
-101
- C1 -
4P32
2
LPTB_ECOLI
B:
[3-230]
---
L
T
A
K
N
L
A
K
A
Y
K
-----
G
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
-----
D
DISLL
P
L
H
--
A
R
A
-
R
R
-----
G
I
G
Y
L
P
Q
E
A
S
I
F
R
R
L
S
V
Y
D
N
L
-
M
A
-
V
-----------
L
Q
I
R
----------
D
----
D
LSA
E
Q
R
E
D
R
A
N
E
---------
L
-
M
E
--
E
F
-
H
--
I
E
H
L
R
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
-
D
-
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
----
I
L
Q
----
D
E
H
V
--
K
------
22
PsiBlast_CBE
81.45
33%
-102
- C1 -
4QC2
2
?
B:
[2-236]
-
A
T
L
T
A
K
N
L
A
K
A
Y
K
-----
G
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
-----
D
DISLL
P
L
H
--
A
R
A
-
R
R
-----
G
I
G
Y
L
P
Q
E
A
S
I
F
R
R
L
S
V
Y
D
N
L
-
M
A
-
V
-----------
L
Q
I
R
----------
D
----
D
LSA
E
Q
R
E
D
R
A
N
E
---------
L
-
M
E
--
E
F
-
H
--
I
E
H
L
R
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
-
D
-
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
----
I
L
Q
----
D
E
H
V
--
K
R
V
Y
L
G
-
24
PsiBlast_CBE
81.17
32%
-100
- C1 -
4P33
6
LPTB_ECOLI
B:
[3-235]
---
L
T
A
K
N
L
A
K
A
Y
K
-----
G
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
-----
D
DISLL
P
L
H
--
A
R
A
-
R
R
-----
G
I
G
Y
L
P
Q
E
A
S
I
F
R
R
L
S
V
Y
D
N
L
-
M
A
-
V
-----------
L
Q
I
R
----------
D
----
D
LSA
E
Q
R
E
D
R
A
N
E
---------
L
-
M
E
--
E
F
-
H
--
I
E
H
L
R
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
Q
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
-
D
-
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
----
I
L
Q
----
D
E
H
V
--
K
R
V
Y
L
G
-
9
PsiBlast_PDB
80.97
32%
-99
- C1 -
4P33
7
LPTB_ECOLI
A:
[3-235]
---
L
T
A
K
N
L
A
K
A
Y
K
-----
G
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
-----
D
DISLL
P
L
H
--
A
R
A
-
R
R
-----
G
I
G
Y
L
P
Q
E
A
S
I
F
R
R
L
S
V
Y
D
N
L
-
M
A
-
V
-----------
L
Q
I
R
----------
D
----
D
LS
A
E
Q
R
E
D
R
A
N
E
---------
L
-
M
E
--
E
F
-
H
--
I
E
H
L
R
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
Q
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
-
D
-
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
----
I
L
Q
----
D
E
H
V
--
K
R
V
Y
L
G
-
21
PsiBlast_CBE
77.39
36%
-93
- C1 -
4WBS
1
?
B:
[38-277]
-
S
S
L
V
V
R
N
L
K
K
R
Y
G
-----
S
R
T
V
V
K
D
V
S
L
D
V
K
S
G
E
V
V
G
L
L
G
P
N
G
A
G
K
T
T
S
F
Y
M
I
V
G
L
V
P
L
D
A
G
E
I
D
L
D
G
-----
K
-----
S
I
S
--
L
L
P
-
I
H
K
R
A
S
L
G
L
S
Y
L
P
Q
E
A
S
V
F
R
K
L
S
V
E
E
N
I
R
---
A
-----------
V
L
E
L
----------
Q
----
V
---
G
--
G
K
R
L
S
K
D
A
I
A
S
R
T
E
A
L
-
L
D
--
E
L
Q
I
--
S
H
L
R
E
N
P
-
A
L
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
T
N
P
S
F
I
L
L
D
E
P
F
A
G
V
D
P
I
A
V
L
E
I
Q
K
I
V
K
F
L
K
-
Q
-
R
N
I
G
V
L
I
T
D
H
N
V
R
E
T
L
G
I
C
D
H
A
Y
I
I
S
D
G
S
V
L
A
A
G
A
P
G
D
----
I
I
E
----
N
E
S
V
--
R
R
V
Y
L
G
E
3
PsiBlast_PDB
75.57
36%
-98
- C1 -
4WBS
1
?
A:
[38-277]
-
S
S
L
V
V
R
N
L
K
K
R
Y
G
-----
S
R
T
V
V
K
D
V
S
L
D
V
K
S
G
E
V
V
G
L
L
G
P
N
G
A
G
K
T
T
S
F
Y
M
I
V
G
L
V
P
L
D
A
G
E
I
D
L
D
G
-----
K
-----
S
I
S
--
L
L
P
-
I
H
K
R
A
S
L
G
L
S
Y
L
P
Q
E
A
S
V
F
R
K
L
S
V
E
E
N
I
R
---
A
-----------
V
L
E
L
----------
Q
----
V
---
G
D
D
G
K
R
L
S
K
D
A
I
A
S
R
T
E
A
L
-
L
D
--
E
L
Q
I
--
S
H
L
R
E
N
P
-
A
L
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
T
N
P
S
F
I
L
L
D
E
P
F
A
G
V
D
P
I
A
V
L
E
I
Q
K
I
V
K
F
L
K
-
Q
-
R
N
I
G
V
L
I
T
D
H
N
V
R
E
T
L
G
I
C
D
H
A
Y
I
I
S
D
G
S
V
L
A
A
G
A
P
G
D
----
I
I
E
----
N
E
S
V
--
R
R
V
Y
L
G
E
52
HHSearch
75.35
30%
-97
- C1 -
1G6H
3
LIVG_METJA
A:
[5-256]
M
E
I
L
R
T
E
N
I
V
K
Y
F
G
-----
E
F
K
A
L
D
G
V
S
I
S
V
N
K
G
D
V
T
L
I
I
G
P
N
G
S
G
K
S
T
L
I
N
V
I
T
G
F
L
K
A
D
E
G
R
V
Y
F
E
N
-----
K
-----
D
I
T
--
N
K
E
-
P
A
E
L
Y
H
Y
G
I
V
R
T
F
Q
T
P
Q
P
L
K
E
M
T
V
L
E
N
L
L
I
G
-
E
-----------
I
C
P
G
ES
P
L
N
S
L
F
Y
K
K
WIPK
E
---
E
E
M
V
E
K
A
F
K
---------
I
-
L
E
--
F
L
K
---
L
S
H
L
Y
D
R
K
A
G
E
L
S
G
G
Q
M
K
L
V
E
I
G
R
A
L
M
T
N
P
K
M
I
V
M
D
E
P
I
A
G
V
A
P
G
L
A
H
D
I
F
N
H
V
L
E
L
K
-
A
-
K
G
I
T
F
L
I
I
E
H
R
L
D
I
V
L
N
Y
I
D
H
L
Y
V
M
F
N
G
Q
I
I
A
E
G
R
G
E
E
----
E
I
K
N
V
L
S
D
P
K
V
--
V
E
I
Y
I
G
E
2
PsiBlast_PDB
74.66
29%
-103
- C1 -
1G6H
3
LIVG_METJA
A:
[5-256]
M
E
I
L
R
T
E
N
I
V
K
Y
F
G
-----
E
F
K
A
L
D
G
V
S
I
S
V
N
K
G
D
V
T
L
I
I
G
P
N
G
S
G
K
S
T
L
I
N
V
I
T
G
F
L
K
A
D
E
G
R
V
Y
F
E
N
-----
K
-----
D
I
T
--
N
K
E
-
P
A
E
L
Y
H
Y
G
I
V
R
T
F
Q
T
P
Q
P
L
K
E
M
T
V
L
E
N
L
L
I
G
-
E
I
C
PGES
P
L
N
S
L
F
Y
K
K
----------
W
----
I
---
P
K
E
E
E
M
V
E
K
---------
A
-
F
K
I
L
E
F
L
K
--
L
S
H
L
Y
D
R
K
A
G
E
L
S
G
G
Q
M
K
L
V
E
I
G
R
A
L
M
T
N
P
K
M
I
V
M
D
E
P
I
A
G
V
A
P
G
L
A
H
D
I
F
N
H
V
L
E
L
K
-
A
-
K
G
I
T
F
L
I
I
E
H
R
L
D
I
V
L
N
Y
I
D
H
L
Y
V
M
F
N
G
Q
I
I
A
E
G
R
G
E
E
E
I
K
N
V
L
S
----
D
P
K
V
--
V
E
I
Y
I
G
E
4
PsiBlast_PDB
71.37
29%
-95
- C1 -
1GAJ
7
LIVG_METJA
A:
[5-256]
M
E
I
L
R
T
E
N
I
V
K
Y
F
G
-----
E
F
K
A
L
D
G
V
S
I
S
V
N
K
G
D
V
T
L
I
I
G
P
N
G
S
G
K
S
T
L
I
N
V
I
T
G
F
L
K
A
D
E
G
R
V
Y
F
E
N
-----
K
-----
D
I
T
--
N
K
E
-
P
A
E
L
Y
H
Y
G
I
V
R
T
F
Q
T
P
Q
P
L
K
E
M
T
V
L
E
N
L
L
I
G
-
E
INPGES
P
L
N
S
L
F
Y
K
K
----------
W
----
I
---
P
K
E
E
E
M
V
E
K
---------
A
-
F
K
I
L
E
F
L
K
--
L
S
H
L
Y
D
R
K
A
G
E
L
S
G
G
Q
M
K
L
V
E
I
G
R
A
L
M
T
N
P
K
M
I
V
M
D
Q
P
I
A
G
V
A
P
G
L
A
H
D
I
F
N
H
V
L
E
L
K
-
A
-
K
G
I
T
F
L
I
I
E
H
R
L
D
I
V
L
N
Y
I
D
H
L
Y
V
M
F
N
G
Q
I
I
A
E
G
R
G
E
E
E
I
K
N
V
L
S
----
D
P
K
V
--
V
E
I
Y
I
G
E
5
PsiBlast_PDB
67.73
29%
-95
- C1 -
1G9X
4
LIVG_METJA
A:
[5-256]
M
E
I
L
R
T
E
N
I
V
K
Y
F
G
-----
E
F
K
A
L
D
G
V
S
I
S
V
C
K
G
D
V
T
L
I
I
G
P
N
G
S
G
K
S
T
L
I
N
V
I
T
G
F
L
K
A
D
E
G
R
V
Y
F
E
N
-----
K
-----
D
I
T
--
N
K
E
-
P
A
E
L
Y
H
Y
G
I
V
R
T
F
Q
T
P
Q
P
L
K
E
M
T
V
L
E
N
L
L
I
G
-
E
INPGES
P
L
N
S
L
F
Y
K
K
----------
W
----
I
---
P
K
E
E
E
M
V
E
K
---------
A
-
F
K
I
L
E
F
L
K
--
L
S
H
L
Y
D
R
K
A
G
E
L
S
G
G
Q
M
K
L
V
E
I
G
R
A
L
M
T
N
P
K
M
I
V
M
D
E
P
I
A
G
V
A
P
G
L
A
H
D
I
F
N
H
V
L
E
L
K
-
A
-
K
G
I
T
F
L
I
I
E
H
R
L
D
I
V
L
N
Y
I
D
H
L
Y
V
M
F
N
G
Q
I
I
A
E
G
R
G
E
E
E
I
K
N
V
L
S
----
D
P
K
V
--
V
E
I
Y
I
G
-
27
PsiBlast_CBE
67.28
32%
-83
- C1 -
4MKI
4
ECFA2_CALS4
B:
[7-236]
---
I
K
V
E
N
V
S
F
I
Y
N
EGTPY
A
T
V
A
L
K
D
I
N
F
S
I
D
D
E
E
F
V
G
I
I
G
H
T
G
S
G
K
S
T
L
I
Q
Q
L
N
G
L
L
K
P
S
K
G
K
I
Y
I
N
G
IDITD
K
-----
K
V
S
--
L
K
D
-
I
R
K
Q
V
G
L
-
V
F
Q
Y
P
E
-
Y
Q
L
F
E
E
-
T
V
F
K
D
I
A
F
G
P
S
-----------
N
L
G
L
----------
S
----
E
---
E
E
V
K
E
R
V
Y
E
---------
A
-
M
E
--
I
V
G
I
--
S
K
E
L
A
D
K
S
P
F
E
L
S
G
G
Q
K
R
R
V
A
I
A
G
I
L
A
M
R
P
K
I
L
I
L
D
E
P
T
A
G
L
D
P
K
G
K
Q
E
I
L
N
K
I
K
E
I
H
D
K
-
Y
K
M
I
T
I
L
V
S
H
N
M
E
D
I
A
R
I
A
D
K
I
I
V
M
N
R
G
K
I
E
L
I
G
T
P
R
E
----
V
F
R
----
E
A
E
R
--
L
E
K
I
G
L
S
28
PsiBlast_CBE
66.87
32%
-80
- C1 -
4MKI
4
ECFA2_CALS4
A:
[7-236]
---
I
K
V
E
N
V
S
F
I
Y
N
EGTPY
A
T
V
A
L
K
D
I
N
F
S
I
D
D
E
E
F
V
G
I
I
G
H
T
G
S
G
K
S
T
L
I
Q
Q
L
N
G
L
L
K
P
S
K
G
K
I
Y
I
N
G
IDITD
K
-----
K
V
S
--
L
K
D
-
I
R
K
Q
V
G
L
-
V
F
Q
Y
P
E
-
Y
Q
L
F
E
E
-
T
V
F
K
D
I
A
F
G
P
S
-----------
N
L
G
L
----------
S
----
E
---
E
E
V
K
E
R
V
Y
E
---------
A
-
M
E
--
I
V
G
I
--
S
K
E
L
A
D
K
S
P
F
E
L
S
G
G
Q
K
R
R
V
A
I
A
G
I
L
A
M
R
P
K
I
L
I
L
D
E
P
T
A
G
L
D
P
K
G
K
Q
E
I
L
N
K
I
K
E
I
H
D
K
-
Y
K
M
I
T
I
L
V
S
H
N
M
E
D
I
A
R
I
A
D
K
I
I
V
M
N
R
G
K
I
E
L
I
G
T
P
R
E
----
V
F
R
----
E
A
E
R
--
L
E
K
I
G
L
S
36
HHSearch
66.72
30%
-82
- C1 -
1Z47
1
?
A:
[14-238]
--
T
I
E
F
V
G
V
E
K
I
Y
P
G----
G
A
R
S
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
-----
K
-----
R
V
T
--
D
L
P
-
P
---
Q
K
R
N
V
G
L
V
F
Q
N
Y
A
L
F
Q
H
M
T
V
Y
D
N
V
S
F
G
-
L
-----------
R
E
K
R
----------
V
----
P
K
--
D
E
M
D
A
R
V
R
E
---------
L
-
L
R
--
F
M
R
---
L
E
S
Y
A
N
R
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
-
D
E
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
E
----
V
Y
E
----
K
P
G
T
--
L
F
V
A
S
F
I
15
PsiBlast_PDB
66.05
29%
-90
- C1 -
4YMW
-
?
J:
[1-224]
--
M
I
F
V
N
D
V
Y
K
N
F
G
-----
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
-----
V
-----
K
I
N
NG
K
V
N
-
I
N
K
-
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
-
P
-----------
V
--
K
----------
V
----
K
---
K
M
N
K
K
E
A
E
E
---------
L
A
V
D
--
L
L
A
K
VG
L
L
D
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
----
I
F
Y
----
R
A
K
N
--
E
R
T
R
E
F
L
14
PsiBlast_PDB
66.03
29%
-90
- C1 -
4YMV
1
?
J:
[1-224]
--
M
I
F
V
N
D
V
Y
K
N
F
G
-----
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
-----
V
-----
K
I
N
NG
K
V
N
-
I
N
K
-
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
-
P
-----------
V
--
K
----------
V
----
K
---
K
M
N
K
K
E
A
E
E
---------
L
A
V
D
--
L
L
A
K
VG
L
L
D
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
----
I
F
Y
----
R
A
K
N
--
E
R
T
R
E
F
L
51
HHSearch
66.02
25%
-89
- C1 -
2OLJ
4
?
A:
[22-260]
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
-----
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-----
I
-----
N
L
K
--
A
K
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-
P
-----------
M
K
V
R
----------
K
WP--
R
---
E
K
A
E
A
K
A
M
E
---------
L
-
L
D
--
K
V
G
---
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
----
L
F
D
----
R
P
Q
H
E
R
T
K
A
F
L
S
K