@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1629: (2015-12-09 )
MALLEVKNLSKHFGGLTAVGDVSMKLHKGELIGLIGPNGAGKTTLFNLLTGVYLPSKGTISLDGKILNGRKPAKIASLGLGRTFQNIRLFKNMTVLDNVLVGLSNHHLSHPIASFLRLPKYYHSEKALRKKALELLEIFGLKAYQDALAKNLPYGKQRRLEIVRALATEPKILFLDEPAAGMNPQETAELTQLISQIKSDFDITIMLIEHDMNLVMQVTERIYVLEYGRLIAHGTPEEIKNNKRVIEAYLGGEL
Atome Classification :
(21 SA)
-.........10..--..----....-20........30........40........50........60...------...--.--.70........80........90........100----.........110.......120.......130.......140...--....150.......160......-.170.......180.......190.......200.......210.......220.....-..230...-...----.240--.--.....-..250..-----------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-MA
L
L
E
V
K
N
L
S
K
HF--GG----
L
T
A
V-G
D
V
S
M
K
LHK
G
E
L
I
G
L
IGPNGA
G
K
T
T
L
F
N
L
L
T
G
VYLPSK
G
T
I
S
LD
G
------
K
IL--N--GRKP
A
K
I
A
SLGLG
R
T
F
Q
N
I
R
L
F
K
N
M
T
V
L
D
N
V
L
------
V
G
LSNHHLS
H
P
I
A
S
F
L
R
L
P
K
Y
Y
H
S
E
K
A
L
R
K
K
A
L
E
L
L
E
I
FG
L
K
A
Y
Q
--
D
A
L
A
KNLPY
G
K
Q
R
R
L
E
I
V
R
A
L
AT-E
P
K
I
L
F
L
DEPAAGM
N
P
Q
E
T
A
E
L
T
Q
L
I
S
Q
I
KSDF
D
I
T
I
M
L
IEHD
M
N
L
V
M
Q
V
T
E
R
I
Y
V
L
EY-
G
R
L
IAHG
T
-
P
E
E
----
I
KN---
N
--
K
R
V
I
E
-
A
Y
LGGEL-----------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
92.88
35%
-108
- C1 -
1G6H
3
LIVG_METJA
A:
[5-256]
-
M
E
I
L
R
T
E
N
I
V
K
Y
F
--
G
E
----
F
K
A
L
-
D
G
V
S
I
S
V
N
K
G
D
V
T
L
I
I
G
P
N
G
S
G
K
S
T
L
I
N
V
I
T
G
F
L
K
A
D
E
G
R
V
Y
F
E
N
------
K
D
I
--
T
--
N
K
E
P
A
E
L
Y
H
Y
G
I
V
R
T
F
Q
T
P
Q
P
L
K
E
M
T
V
L
E
N
L
L
------
I
G
E
I
C
P
G
E
S
-
P
L
N
S
-
L
F
Y
K
K
W
I
P
K
E
E
E
M
V
E
K
A
F
K
I
L
E
F
L
K
L
S
H
L
Y
--
D
R
K
A
G
E
L
S
G
G
Q
M
K
L
V
E
I
G
R
A
L
M
T
-
N
P
K
M
I
V
M
D
E
P
I
A
G
V
A
P
G
L
A
H
D
I
F
N
H
V
L
E
L
K
A
K
-
G
I
T
F
L
I
I
E
H
R
L
D
I
V
L
N
Y
I
D
H
L
Y
V
M
F
N
-
G
Q
I
I
A
E
G
R
G
E
E
E
----
I
K
N
V
L
S
D
--
P
K
V
V
E
-
I
Y
I
G
E
-------------------------------------------------------------------------------------------------------------
33
Fugue
92.17
33%
-113
- C1 -
1Z47
1
?
A:
[11-355]
G
S
M
T
I
E
F
V
G
V
E
K
I
Y
P-
G
G
----
A
R
S
V
-
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
------
K
R
V
--
T
--
D
L
P
P
Q
K
---
R
N
V
G
L
V
F
Q
N
Y
A
L
F
Q
H
M
T
V
Y
D
N
V
S
------
F
G
L
R
E
K
R
---------------
V
P
K
D
E
M
D
A
R
V
R
E
L
L
R
F
M
R
L
E
S
Y
A
--
N
R
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
-
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
E
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
-
G
N
V
E
Q
F
G
T
-
P
E
E
----
V
Y
E
---
K
PG
T
L
F
V
A
-
S
F
I
G
E
S
N
V
W
T
R
A
V
Q
NG
R
I
E
V
AG
A
A
L
P
V
DPAVSEG
S
E
V
A
V
V
V
R
PKD
V
E
L
Q
P
A
S
EREAHAQVV
R
S
A
F
KGS
Y
S
A
C
W
I
R
T
KD
G
E
V
W
E
V
H
V
P
SADRHRWSPG
A
W
V
H
M
N
V
T
R
W
F
I
F
P
R--
2
PsiBlast_PDB
89.72
35%
-102
- C1 -
1GAJ
7
LIVG_METJA
A:
[5-256]
-
M
E
I
L
R
T
E
N
I
V
K
Y
F
--
G
E
----
F
K
A
L
-
D
G
V
S
I
S
V
N
K
G
D
V
T
L
I
I
G
P
N
G
S
G
K
S
T
L
I
N
V
I
T
G
F
L
K
A
D
E
G
R
V
Y
F
E
N
------
K
D
I
--
T
--
N
K
E
P
A
E
L
Y
H
Y
G
I
V
R
T
F
Q
T
P
Q
P
L
K
E
M
T
V
L
E
N
L
L
------
I
G
E
I
N
P
G
E
S
-
P
L
N
S
-
L
F
Y
K
K
W
I
P
K
E
E
E
M
V
E
K
A
F
K
I
L
E
F
L
K
L
S
H
L
Y
--
D
R
K
A
G
E
L
S
G
G
Q
M
K
L
V
E
I
G
R
A
L
M
T
-
N
P
K
M
I
V
M
D
Q
P
I
A
G
V
A
P
G
L
A
H
D
I
F
N
H
V
L
E
L
K
A
K
-
G
I
T
F
L
I
I
E
H
R
L
D
I
V
L
N
Y
I
D
H
L
Y
V
M
F
N
-
G
Q
I
I
A
E
G
R
G
E
E
E
----
I
K
N
V
L
S
D
--
P
K
V
V
E
-
I
Y
I
G
E
-------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
89.05
36%
-99
- C1 -
1G9X
4
LIVG_METJA
A:
[5-256]
-
M
E
I
L
R
T
E
N
I
V
K
Y
F
--
G
E
----
F
K
A
L
-
D
G
V
S
I
S
V
C
K
G
D
V
T
L
I
I
G
P
N
G
S
G
K
S
T
L
I
N
V
I
T
G
F
L
K
A
D
E
G
R
V
Y
F
E
N
------
K
D
I
--
T
--
N
K
E
P
A
E
L
Y
H
Y
G
I
V
R
T
F
Q
T
P
Q
P
L
K
E
M
T
V
L
E
N
L
L
------
I
G
E
I
N
P
G
E
S
-
P
L
N
S
-
L
F
Y
K
K
W
I
P
K
E
E
E
M
V
E
K
A
F
K
I
L
E
F
L
K
L
S
H
L
Y
--
D
R
K
A
G
E
L
S
G
G
Q
M
K
L
V
E
I
G
R
A
L
M
T
-
N
P
K
M
I
V
M
D
E
P
I
A
G
V
A
P
G
L
A
H
D
I
F
N
H
V
L
E
L
K
A
K
-
G
I
T
F
L
I
I
E
H
R
L
D
I
V
L
N
Y
I
D
H
L
Y
V
M
F
N
-
G
Q
I
I
A
E
G
R
G
E
E
E
----
I
K
N
V
L
S
D
--
P
K
V
V
E
-
I
Y
I
G
--------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
87.87
33%
-105
- C1 -
4QC2
2
?
A:
[2-236]
--
A
T
L
T
A
K
N
L
A
K
A
Y
--
K
G
----
R
R
V
V
-
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
------
D
D
I
--
S
--
L
L
P
L
H
A
R
A
R
R
G
I
G
Y
L
P
Q
E
A
S
I
F
R
R
L
S
V
Y
D
N
L
M
-------------------
A
V
L
Q
I
R
D
D
L
S
A
E
Q
R
-
E
D
R
A
N
E
L
M
E
E
F
H
I
E
H
L
R
--
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
-
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
-
D
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
-
G
H
L
I
A
H
G
T
-
P
T
E
----
I
L
Q
---
D
--
E
H
V
K
R
-
V
Y
L
G
--------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
87.75
33%
-107
- C1 -
4QC2
2
?
B:
[2-236]
--
A
T
L
T
A
K
N
L
A
K
A
Y
--
K
G
----
R
R
V
V
-
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
------
D
D
I
--
S
--
L
L
P
L
H
A
R
A
R
R
G
I
G
Y
L
P
Q
E
A
S
I
F
R
R
L
S
V
Y
D
N
L
M
-------------------
A
V
L
Q
I
R
D
D
L
S
A
E
Q
R
-
E
D
R
A
N
E
L
M
E
E
F
H
I
E
H
L
R
--
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
-
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
-
D
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
-
G
H
L
I
A
H
G
T
-
P
T
E
----
I
L
Q
---
D
--
E
H
V
K
R
-
V
Y
L
G
--------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
87.24
33%
-109
- C1 -
4P33
7
LPTB_ECOLI
A:
[1-235]
--
A
T
L
T
A
K
N
L
A
K
A
Y
--
K
G
----
R
R
V
V
-
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
------
D
D
I
--
S
--
L
L
P
L
H
A
R
A
R
R
G
I
G
Y
L
P
Q
E
A
S
I
F
R
R
L
S
V
Y
D
N
L
M
-------------------
A
V
L
Q
I
R
D
D
L
S
A
E
Q
R
-
E
D
R
A
N
E
L
M
E
E
F
H
I
E
H
L
R
--
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
-
N
P
K
F
I
L
L
D
Q
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
-
D
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
-
G
H
L
I
A
H
G
T
-
P
T
E
----
I
L
Q
---
D
--
E
H
V
K
R
-
V
Y
L
G
--------------------------------------------------------------------------------------------------------------
30
Fugue
87.23
35%
-109
- C1 -
1G6H
3
LIVG_METJA
A:
[4-257]
T
M
E
I
L
R
T
E
N
I
V
K
Y
F
--
G
-E---
F
K
A
L
D-
G
V
S
I
S
V
N
K
G
D
V
T
L
I
I
G
P
N
G
S
G
K
S
T
L
I
N
V
I
T
G
F
L
K
A
D
E
G
R
V
Y
F
E
N
KDITNK----------
E
P
A
E
L
Y
H
Y
G
I
V
R
T
F
Q
T
P
Q
P
L
K
E
M
T
V
L
E
N
L
L
------
I
G
E
I
C
P
G
E
S
P
L
N
S
L
F
Y
K
K
W
I
--
P
K
E
E
E
M
V
E
K
A
F
K
I
L
E
F
L
K
L
-
S
H
L
YD-
R
K
A
G
E
L
S
G
G
Q
M
K
L
V
E
I
G
R
A
L
M
T
N-
P
K
M
I
V
M
D
E
P
I
A
G
V
A
P
G
L
A
H
D
I
F
N
H
V
L
E
L
K
A
K
-
G
I
T
F
L
I
I
E
H
R
L
D
I
V
L
N
Y
I
D
H
L
Y
V
M
F
-N
G
Q
I
I
A
E
G
R
-
G
E
E
E
I
K
N
V
L
S
---
D
--
P
K
V
V
E
-
I
Y
I
G
E
-------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
87.23
33%
-106
- C1 -
4P33
6
LPTB_ECOLI
B:
[1-235]
--
A
T
L
T
A
K
N
L
A
K
A
Y
--
K
G
----
R
R
V
V
-
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
------
D
D
I
--
S
--
L
L
P
L
H
A
R
A
R
R
G
I
G
Y
L
P
Q
E
A
S
I
F
R
R
L
S
V
Y
D
N
L
M
-------------------
A
V
L
Q
I
R
D
D
L
S
A
E
Q
R
-
E
D
R
A
N
E
L
M
E
E
F
H
I
E
H
L
R
--
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
-
N
P
K
F
I
L
L
D
Q
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
-
D
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
-
G
H
L
I
A
H
G
T
-
P
T
E
----
I
L
Q
---
D
--
E
H
V
K
R
-
V
Y
L
G
--------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
86.88
36%
-109
- C1 -
1G9X
3
LIVG_METJA
B:
[5-256]
-
M
E
I
L
R
T
E
N
I
V
K
Y
F
--
G
E
----
F
K
A
L
-
D
G
V
S
I
S
V
C
K
G
D
V
T
L
I
I
G
P
N
G
S
G
K
S
T
L
I
N
V
I
T
G
F
L
K
A
D
E
G
R
V
Y
F
E
N
------
K
D
I
--
T
--
N
K
E
P
A
E
L
Y
H
Y
G
I
V
R
T
F
Q
T
P
Q
P
L
K
E
M
T
V
L
E
N
L
L
------
I
G
E
I
N
P
G
E
S
-
P
L
N
S
-
L
F
Y
K
K
W
I
P
K
E
E
E
M
V
E
K
A
F
K
I
L
E
F
L
K
L
S
H
L
Y
--
D
R
K
A
G
E
L
S
G
G
Q
M
K
L
V
E
I
G
R
A
L
M
T
-
N
P
K
M
I
V
M
D
E
P
I
A
G
V
A
P
G
L
A
H
D
I
F
N
H
V
L
E
L
K
A
K
-
G
I
T
F
L
I
I
E
H
R
L
D
I
V
L
N
Y
I
D
H
L
Y
V
M
F
N
-
G
Q
I
I
A
E
G
R
G
E
E
E
----
I
K
N
VLS
D
--
P
K
V
V
E
-
I
Y
I
G
--------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
86.38
36%
-99
- C1 -
1G9X
3
LIVG_METJA
C:
[5-256]
-
M
E
I
L
R
T
E
N
I
V
K
Y
F
--
G
E
----
F
K
A
L
-
D
G
V
S
I
S
V
C
K
G
D
V
T
L
I
I
G
P
N
G
S
G
K
S
T
L
I
N
V
I
T
G
F
L
K
A
D
E
G
R
V
Y
F
E
N
------
K
D
I
--
T
--
N
K
E
P
A
E
L
Y
H
Y
G
I
V
R
T
F
Q
T
P
Q
P
L
K
E
M
T
V
L
E
N
L
L
------
I
G
E
I
N
P
G
E
S
-
P
L
N
S
-
L
F
Y
K
K
W
I
P
K
E
E
E
M
V
E
K
A
F
K
I
L
E
F
L
K
L
S
H
L
Y
--
D
R
K
A
G
E
L
S
G
G
Q
M
K
L
V
E
I
G
R
A
L
M
T
-
N
P
K
M
I
V
M
D
E
P
I
A
G
V
A
P
G
L
A
H
D
I
F
N
H
V
L
E
L
K
A
K
-
G
I
T
F
L
I
I
E
H
R
L
D
I
V
L
N
Y
I
D
H
L
Y
V
M
F
N
-
G
Q
I
I
A
E
G
R
G
E
E
E
----
I
K
N
VLS
D
--
P
K
V
V
E
-
I
Y
I
G
--------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
85.44
33%
-110
- C1 -
4P32
2
LPTB_ECOLI
B:
[1-230]
--
A
T
L
T
A
K
N
L
A
K
A
Y
--
K
G
----
R
R
V
V
-
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
------
D
D
I
--
S
--
L
L
P
L
H
A
R
A
R
R
G
I
G
Y
L
P
Q
E
A
S
I
F
R
R
L
S
V
Y
D
N
L
M
-------------------
A
V
L
Q
I
R
D
D
L
S
A
E
Q
R
-
E
D
R
A
N
E
L
M
E
E
F
H
I
E
H
L
R
--
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
-
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
-
D
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
-
G
H
L
I
A
H
G
T
-
P
T
E
----
I
L
Q
---
D
--
E
H
V
K
--------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
85.11
33%
-107
- C1 -
4P32
2
LPTB_ECOLI
A:
[1-234]
--
A
T
L
T
A
K
N
L
A
K
A
Y
--
K
G
----
R
R
V
V
-
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
------
D
D
I
--
S
--
L
L
P
L
H
A
R
A
R
R
G
I
G
Y
L
P
Q
E
A
S
I
F
R
R
L
S
V
Y
D
N
L
M
-------------------
A
V
L
Q
I
R
D
D
L
S
A
E
Q
R
-
E
D
R
A
N
E
L
M
E
E
F
H
I
E
H
L
R
--
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
-
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
-
D
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
-
G
H
L
I
A
H
G
T
-
P
T
E
----
I
L
Q
---
D
--
E
H
V
K
R
-
V
Y
L
---------------------------------------------------------------------------------------------------------------
56
HHSearch
83.98
35%
-107
- C1 -
1G6H
3
LIVG_METJA
A:
[5-243]
-
M
E
I
L
R
T
E
N
I
V
K
Y
F
--
G
E
----
F
K
A
L
-
D
G
V
S
I
S
V
N
K
G
D
V
T
L
I
I
G
P
N
G
S
G
K
S
T
L
I
N
V
I
T
G
F
L
K
A
D
E
G
R
V
Y
F
E
N
------
K
D
I
--
T
--
N
K
E
P
A
E
L
Y
H
Y
G
I
V
R
T
F
Q
T
P
Q
P
L
K
E
M
T
V
L
E
N
L
L
------
I
G
E
I
C
P
G
E
S
P
L
N
S
L
F
--
Y
K
K
W
I
P
K
E
E
E
M
V
E
K
A
F
K
I
L
E
F
L
K
L
S
H
L
Y
--
D
R
K
A
G
E
L
S
G
G
Q
M
K
L
V
E
I
G
R
A
L
M
T
-
N
P
K
M
I
V
M
D
E
P
I
A
G
V
A
P
G
L
A
H
D
I
F
N
H
V
L
E
L
K
A
-
K
G
I
T
F
L
I
I
E
H
R
L
D
I
V
L
N
Y
I
D
H
L
Y
V
M
F
N
-
G
Q
I
I
A
E
G
R
-
G
E
E
----
E
I
K
---
N
--
V
L
S
D
P
-
K
V
V
E
I
Y
I
-----------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
83.25
33%
-107
- C1 -
4WBS
1
?
B:
[40-277]
----
L
V
V
R
N
L
K
K
R
Y
--
G
S
----
R
T
V
V
-
K
D
V
S
L
D
V
K
S
G
E
V
V
G
L
L
G
P
N
G
A
G
K
T
T
S
F
Y
M
I
V
G
L
V
P
L
D
A
G
E
I
D
L
D
G
------
K
S
I
--
S
--
L
L
P
I
H
K
R
A
S
L
G
L
S
Y
L
P
Q
E
A
S
V
F
R
K
L
S
V
E
E
N
I
R
A
V
L
E
L
Q
V
G
--
G
K
R
L
---------------
S
K
D
A
I
A
S
R
T
E
A
L
L
D
E
L
Q
I
S
H
L
R
--
E
N
P
A
L
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
T
-
N
P
S
F
I
L
L
D
E
P
F
A
G
V
D
P
I
A
V
L
E
I
Q
K
I
V
K
F
L
K
Q
R
-
N
I
G
V
L
I
T
D
H
N
V
R
E
T
L
G
I
C
D
H
A
Y
I
I
S
D
-
G
S
V
L
A
A
G
A
-
P
G
D
----
I
I
E
---
N
--
E
S
V
R
R
-
V
Y
L
G
E
H
F
-----------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
83.05
33%
-106
- C1 -
4WBS
1
?
A:
[40-277]
----
L
V
V
R
N
L
K
K
R
Y
--
G
S
----
R
T
V
V
-
K
D
V
S
L
D
V
K
S
G
E
V
V
G
L
L
G
P
N
G
A
G
K
T
T
S
F
Y
M
I
V
G
L
V
P
L
D
A
G
E
I
D
L
D
G
------
K
S
I
--
S
--
L
L
P
I
H
K
R
A
S
L
G
L
S
Y
L
P
Q
E
A
S
V
F
R
K
L
S
V
E
E
N
I
R
A
V
L
E
L
Q
V
G
D
D
G
K
R
L
---------------
S
K
D
A
I
A
S
R
T
E
A
L
L
D
E
L
Q
I
S
H
L
R
--
E
N
P
A
L
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
T
-
N
P
S
F
I
L
L
D
E
P
F
A
G
V
D
P
I
A
V
L
E
I
Q
K
I
V
K
F
L
K
Q
R
-
N
I
G
V
L
I
T
D
H
N
V
R
E
T
L
G
I
C
D
H
A
Y
I
I
S
D
-
G
S
V
L
A
A
G
A
-
P
G
D
----
I
I
E
---
N
--
E
S
V
R
R
-
V
Y
L
G
E
H
F
-----------------------------------------------------------------------------------------------------------
34
Fugue
82.53
28%
-115
- C1 -
3TUZ
3
METN_ECOLI
H:
[23-362]
--
H
M
I
K
L
S
N
I
T
K
V
F
--
H
Q
GTRT
I
Q
A
L
-
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
------
Q
E
L
--
T
TL
S
E
S
E
L
T
K
A
R
R
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
A
------
L
P
L
E
L
D
N
T
P
K
---------------
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
K
H
--
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
-
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
-
G
E
L
I
E
Q
D
T
-
V
S
E
----
V
F
S
---
H
PK
T
P
L
A
Q
-
K
F
I
Q
S
T
L
HLDIPEDYQERLQAEPFTDCVPMLRLEFTGQSVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHHVKVEV-------------
31
Fugue
81.70
28%
-111
- C1 -
1OXS
23
?
C:
[1-352]
-
M
V
R
I
I
V
K
N
V
S
K
V
F
--
K
K
GK--
V
V
A
L
-
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
------
R
L
V
--
A
SN
G
K
L
I
V
P
P
E
D
R
K
I
G
M
V
F
Q
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
A
------
F
P
L
T
N
M
K
M
S
---------------
K
E
E
I
R
K
R
V
E
E
V
A
K
I
L
D
I
H
H
V
L
--
N
H
F
P
R
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
-
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
R
V
G
V
L
V
K
-
G
K
L
V
Q
V
G
K
-
P
E
D
----
L
Y
D
---
N
PV
S
I
Q
V
A
-
S
L
I
G
E
I
N
ELEGKVTNEGVVIGSLRFPVSVSSDRAIIGIRPEDVKLSKDVIKDDSWILVGKGKVKVIGYQGGLFRITITPLDSEEEIFTYSDHPIHSGEEVLVYVRKDKIKVFEK
13
PsiBlast_PDB
80.74
28%
-111
- C1 -
1OXU
7
?
A:
[1-244]
-
M
V
R
I
I
V
K
N
V
S
K
V
F
KK
G
K
----
V
V
A
L
-
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
------
R
L
V
AS
N
--
G
K
L
I
V
P
P
E
D
R
K
I
G
M
V
F
Q
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
A
------
F
P
L
T
N
M
K
M
S
---------------
K
E
E
I
R
K
R
V
E
E
V
A
K
I
L
D
I
H
H
V
L
--
N
H
F
P
R
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
-
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
R
V
G
V
L
V
K
-
G
K
L
V
Q
V
G
K
-
P
E
D
----
L
Y
D
---
N
--
P
V
S
I
Q
V
A
S
L
I
G
E
I
-----------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
80.30
28%
-107
- C1 -
1OXV
7
?
A:
[1-244]
-
M
V
R
I
I
V
K
N
V
S
K
V
F
KK
G
K
----
V
V
A
L
-
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
------
R
L
V
AS
N
--
G
K
L
I
V
P
P
E
D
R
K
I
G
M
V
F
Q
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
A
------
F
P
L
T
N
M
K
M
S
---------------
K
E
E
I
R
K
R
V
E
E
V
A
K
I
L
D
I
H
H
V
L
--
N
H
F
P
R
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
-
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
R
V
G
V
L
V
K
-
G
K
L
V
Q
V
G
K
-
P
E
D
----
L
Y
D
---
N
--
P
V
S
I
Q
V
A
S
L
I
G
E
I
-----------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
54.50
33%
-10
- C1 -
4P31
2
LPTB_ECOLI
A:
[1-234]
--
A
T
L
T
A
K
N
L
A
K
A
Y
--
K
G
----
R
R
V
V
-
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
------
D
D
I
--
S
--
L
L
P
L
H
A
R
A
R
R
G
I
G
Y
L
P
Q
E
A
S
I
F
R
R
L
S
V
Y
D
N
-------------------
L
M
A
V
L
Q
I
R
D
D
L
S
A
E
Q
R
-
E
D
R
A
N
E
L
M
E
E
F
H
I
E
H
L
R
--
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
-
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
-
D
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
-
G
H
L
I
A
H
G
T
-
P
T
E
----
I
L
Q
---
D
--
E
H
V
K
R
-
V
Y
L
---------------------------------------------------------------------------------------------------------------