@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1662: (2015-12-09 )
MTEFNDDQHSNHDQKSFKEQILAELEEANRLRKLREEELYQKEQEAKEAARRTAQLMADYEAQRLKDEQEARAKALETKQRLEEQEKARIEAKLLAEAAREEERRQAEQALASQEEQVINQGMEPSRELDSGSKSSEFRTTENVPDIDLKADKTDVATAVPNQETEEIFLVRATDIPTEGENVKLGETSELEPVAKEPIRVEDLSKEEEDIALSAKNKHNKRERRQKADNVAKRIARILISIIILVLLLTAFVGYRFVDSAIKPVDSNSNKFVQVEIPIGSGNKLIGQILEKAGVIKSATVFNYYSKFKNYSNFQSGYYNLKKSMTLDQIAAELEKGGTAEPTKPALGKILITEGYTIKQIAKAIESNKIDTKTTSTPYKADDFLKLVQDETFIKKMVAKYPNLLGSLPDKSKAIYQLEGYLFPATYNYYKDTTLEGLVEDMISTMNTKMAPYYNTIKAKNMSVNDVLTLSSLVEKEGSTDEDRRKIASVFYNRLSAGQALQSNIAILYAMGKLGDKTSLAEDAQINTSIKSPYNIYTNTGLMPGPVDSPSISAIEATIKPASTDYLYFVADVKTGNVYYAKDFETHKANVEKYINSQIN
Atome Classification :
(20 SA)
.........10........20........30.........40........50........60....---....70........80........90........100....-...110-.......120.......130..-------.....140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.....--..300......-------.310-.......320.......330.......340.......350.......360.......370.......380-.........390.......--400.......410.......420......-----.430........440--.........450...-....460........470.......480.......490....---...500.......510-...-....520.......530.......540......-----------.550.......560.......570.......580.......590.......600
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MTEFNDDQHSN
H
D
Q
K
S
F
K
E
Q
I
L
A
E
L
E
E
A
N
R
-
L
R
K
L
R
E
E
E
L
Y
Q
K
E
Q
E
A
K
E
A
A
R
R
T
A
Q
L
M
A
D
Y
E
A
Q
R
L
---
K
D
E
Q
E
A
R
A
K
A
L
E
T
K
Q
R
L
E
E
Q
E
K
A
R
I
E
A
K
L
L
A
E
A
A
R
E
E
E
R
R
Q
-
A
E
Q
A
L
A
-
S
Q
E
E
Q
V
I
N
QGMEP
S
R
ELDSGSK-------SSEFRTTENVPDIDLKADKTD
V
A
TAVPNQET
E
E
I
F
L
V
R
ATDIPTEGENVKLGETSELEPVAKE
P
I
R
V
EDLSKEEE
D
I
A
L
SAKNKH
N
K
R
E
R
R
Q
K
A
D
N
V
A
K
R
I
A
R
I
L
I
S
I
I
I
L
V
L
L
L
T
A
F
V
G
Y
R
F
V
D
S
AIKPVDSNSN
K
F
V
Q
V
E
I
PIGSG
N
K
L
I
G
Q
I
L
E
KAGVIK--
S
A
T
V
F
N
Y
Y
S
K
F-------KNYS-
N
F
Q
S
G
Y
Y
N
L
K
KSM
T
L
D
Q
I
A
A
E
L
E
KGGTAEPTKPAL
G
K
I
L
ITEGY
T
I
K
Q
I
A
K
A
I
ESNKIDTKTTSTPY
K
---
A
D
D
F
L
K
L
VQ
D
E
T
F
I
K
K
M
V
A
--
K
Y
P
N
L
L
GSLPDKS
K
A
I
Y
Q
L
E
G
Y
L
FP
A
T
YN-----YY-KD
T
T
L
E
G
L
V
E
----
D
M
I
S
TMNTKMAP
Y
Y
N
-
T
I
K
AKN-MSV
N
D
V
L
T
L
S
S
L
V
EKEGS
T
D
E
D
R
R
K
I
A
S
V
F
Y
N
RLS---A
G
Q
A
L
Q
SN
I
A
I
L
Y
A
MG-KLG-DKTSLAEDAQINTSIKS
P
Y
N
I
YTNTGLMPGPVD-----------SPSI
S
A
I
E
A
TIKPAST
D
Y
L
Y
F
V
A
DVKTG
N
V
Y
Y
A
KDFE
T
H
K
A
N
V
E
K
Y
I
N
SQIN
1
PsiBlast_PDB
93.27
35%
-70
- C4 -
4IIW
5
?
A:
[35-342]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
E
K
I
T
V
E
I
P
A
G
S
S
I
S
D
I
S
T
I
L
E
D
K
K
V
I
N
--
N
A
S
I
F
S
F
Y
V
K
Y
-------
N
N
D
T
-
N
L
K
A
G
N
Y
E
L
S
P
A
M
N
T
D
Q
I
V
K
K
M
Q
E
G
K
T
V
A
P
-----
A
K
L
V
I
P
E
G
Y
T
L
D
Q
I
A
D
R
I
V
A
Y
Q
P
K
L
K
K
A
----------
D
V
L
K
T
M
D
D
P
E
F
V
A
S
M
I
K
--
A
Y
P
E
T
V
T
N
D
V
L
N
K
S
I
K
H
P
L
E
G
Y
L
Y
P
A
T
Y
T
-----
F
K
G
T
D
V
S
A
E
Q
I
I
T
----
E
M
V
K
A
T
D
V
N
I
A
K
Y
R
D
-
E
L
T
K
Q
K
-
M
S
V
H
K
F
L
T
M
S
S
I
I
E
K
E
A
T
E
N
V
D
R
K
M
I
A
S
V
F
Y
N
R
L
A
---
K
D
M
R
L
Q
T
D
P
T
V
L
Y
A
L
G
-
E
H
K
-
S
K
T
T
Y
K
D
-----
L
E
V
D
S
P
Y
N
T
Y
K
N
N
G
L
P
P
G
P
I
S
-----------
N
S
G
D
S
S
M
E
A
A
L
Y
P
E
K
S
D
Y
L
Y
F
L
A
N
----
K
V
Y
F
S
K
T
L
E
E
H
N
K
L
K
E
--------
11
HHSearch
76.78
28%
-52
- C4 -
2R1F
13
YCEG_ECOLI
A:
[11-265]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
F
K
A
G
T
Y
R
F
T
P
Q
M
T
V
R
E
M
L
K
L
L
E
S
G
K
E
------
A
Q
F
P
L
R
L
V
E
G
M
R
L
S
D
Y
L
K
Q
L
R
E
--------
A
P
Y
I
K
HTL
S
D
D
K
Y
A
T
V
A
Q
A
L
-----
E
L
-----------
E
----
N
P
E
W
I
E
G
W
F
W
P
D
T
W
M
-----
Y
T
-
A
N
T
T
D
V
A
L
L
K
----
R
A
H
K
K
M
V
K
A
V
D
S
A
W
E
G
R
A
D
G
L
P
Y
K
D
K
N
Q
L
V
T
M
A
S
I
I
E
K
E
T
A
V
A
S
E
R
D
Q
V
A
S
V
F
I
N
R
L
R
---
I
G
M
R
L
Q
T
D
P
T
V
I
Y
G
M
G
-
E
R
Y
N
G
K
L
S
R
A
-----
D
L
E
T
P
T
A
Y
N
T
Y
T
I
T
G
L
P
P
G
A
I
A
-----------
T
P
G
A
D
S
L
K
A
A
A
H
P
A
K
T
P
Y
L
Y
F
V
A
D
-
G
K
G
G
H
T
F
N
T
N
L
A
S
H
N
K
S
V
Q
D
Y
L
K
V
L
K
E
2
PsiBlast_PDB
71.12
30%
-55
- C4 -
2R1F
11
YCEG_ECOLI
A:
[52-261]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
Y
L
K
Q
L
R
E
A
P
Y
I
K
H
T
L
S
DD
K
Y
A
T
V
A
Q
A
L
E
L
E
N
P
E
--
W
I
E
G
W
F
W
P
D
T
W
M
-----
Y
T
-
A
N
T
T
D
V
A
L
L
K
R
A
H
K
K
M
V
K
A
V
D
S
A
W
E
G
R
A
D
-
G
L
P
Y
K
D
-
K
--
N
Q
L
V
T
M
A
S
I
I
E
K
E
T
A
V
A
S
E
R
D
Q
V
A
S
V
F
I
N
R
L
R
---
I
G
M
R
L
Q
T
D
P
T
V
I
Y
G
M
G
E
R
Y
N
-
G
K
L
S
R
A
-
D
L
E
T
P
T
A
----
Y
N
T
Y
T
I
T
G
L
P
P
G
A
I
A
-----------
T
P
G
A
D
S
L
K
A
A
A
H
P
A
K
T
P
Y
L
Y
F
V
A
D
G
K
G
G
H
T
-
F
N
T
N
L
A
S
H
N
K
S
V
Q
D
Y
L
K
V
L
K
E
21
Fugue
54.49
19%
87
- C3 -
4H22
-
LRRF1_HUMAN
A:
[168-248]
--------------------------------------
E
E
K
Y
K
K
A
M
V
S
N
A
Q
L
D
N
E
K
T
N
F
M
Y
Q
V
D
T
L
---
K
D
M
L
L
E
L
E
E
Q
L
A
E
S
R
R
Q
Y
E
E
K
N
K
E
F
E
R
E
K
H
A
H
S
I
L
Q
F
Q
F
A
E
-
V
K
E
A
L
K
-
Q
R
E
E
M
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
52.24
22%
68
* C3 *
3K5B
-
?
B:
[21-120]
-----------------------------
G
-
L
I
K
S
L
A
E
K
E
K
Q
L
L
E
R
L
E
A
A
K
K
E
A
E
E
R
V
K
R
A
E
A
E
A
K
---
A
L
L
E
E
A
E
A
K
A
K
A
L
E
A
Q
Y
R
E
R
E
R
A
E
T
E
A
L
L
A
R
Y
R
E
R
A
E
A
E
A
K
-
A
V
R
E
K
A
M
A
R
L
D
E
A
V
A
L
V
L
K
E
V
L
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
50.22
12%
76
- C3 -
1X79
3
RABE1_HUMAN
B:
[3-92]
-----------------
E
T
R
D
Q
V
K
K
L
Q
L
M
L
-
R
Q
A
N
D
Q
L
E
K
T
M
K
D
K
Q
E
L
E
D
F
I
K
Q
S
S
E
D
S
S
H
Q
I
S
A
L
---
V
L
R
A
Q
A
S
E
I
L
L
E
E
L
Q
Q
G
L
S
Q
A
K
R
D
V
Q
E
Q
M
A
V
L
M
Q
S
R
E
Q
V
S
E
-
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
50.17
13%
54
- C3 -
4LTB
-
?
A:
[2-172]
----
S
L
S
Q
A
S
A
D
L
E
A
T
L
R
H
K
L
T
V
M
Y
S
Q
I
N
G
-
A
S
R
A
L
D
D
V
R
N
R
Q
Q
D
V
R
M
T
A
N
R
K
V
E
Q
L
Q
Q
E
Y
T
E
M
K
A
L
L
D
A
S
E
T
T
S
T
R
K
I
K
E
E
E
K
R
V
N
S
K
F
D
T
I
Y
Q
I
L
L
K
K
K
S
E
I
Q
T
L
K
E
E
-
I
E
Q
S
L
T
-
K
R
D
E
F
E
F
L
E
K
A
S
K
L
R
G
I
S
T
K
P
V
Y
I
P
EVEL
N
H
K
L
I
K
G
I
H
Q
S
T
I
D
L
K
N
E
L
K
Q
C
I
G
R
L
Q
E
L
T
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
49.41
9%
50
- C3 -
4CPC
-
SYCP3_HUMAN
A:
[18-160]
--
I
N
K
A
L
L
A
K
R
K
R
L
E
M
Y
T
K
A
S
L
K
T
S
N
Q
K
I
E
-
H
V
W
K
T
Q
Q
D
Q
R
Q
K
L
N
Q
E
Y
S
Q
Q
F
L
T
L
F
Q
Q
W
D
L
D
M
Q
K
A
---
E
E
Q
E
E
K
I
L
N
M
F
R
Q
Q
Q
K
I
L
Q
Q
S
R
I
V
Q
S
Q
R
L
K
T
I
K
Q
L
Y
E
Q
F
I
K
-
S
M
E
E
L
E
-
K
N
H
D
N
L
L
T
G
A
Q
N
E
F
K
K
E
M
A
M
L
Q
-------
K
K
I
M
M
E
T
Q
Q
Q
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
48.18
10%
82
- C3 -
3J47
3
U:
[1-121]
-
I
R
L
T
N
Q
L
K
S
L
K
G
L
Q
S
K
L
K
D
V
V
E
Y
L
D
K
V
I
H
-
T
I
L
G
K
L
Q
D
V
F
N
L
N
N
L
Q
K
A
L
T
V
K
T
N
D
E
L
M
V
I
Y
I
S
N
L
---
V
R
S
I
I
A
F
D
D
L
I
E
N
K
I
Q
N
K
K
I
Q
E
Q
R
V
K
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
46.04
12%
57
- C3 -
4NQJ
3
TRI69_HUMAN
A:
[1-177]
---------
S
V
G
Q
S
K
E
F
L
-
Q
I
S
D
A
V
H
F
F
M
E
-
E
L
A
I
Q
Q
G
Q
L
E
T
T
L
K
E
L
Q
T
L
R
N
M
Q
K
E
A
I
A
A
H
K
E
N
K
L
---
H
L
Q
Q
H
V
S
M
E
F
L
K
L
H
Q
F
L
H
S
K
E
K
D
I
L
T
E
L
R
E
E
G
K
A
L
N
E
E
M
E
L
-
N
L
S
Q
L
Q
-
E
Q
C
L
L
A
K
D
M
L
V
S
I
Q
A
K
T
E
Q
Q
N
S
-------
F
D
F
L
K
D
I
T
T
L
L
H
S
L
E
Q
G
M
K
V
L
A
T
R
E
L
I
S
R
K
L
N
L
G
Q
Y
K
G
P
I
Q
Y
M
V
W
R
E
M
Q
D
T
L
C
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
45.91
32%
46
- C4 -
4WR4
1
?
A:
[80-150]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
----
I
D
G
D
V
K
L
T
Q
S
M
A
I
I
R
-
I
A
D
--
K
H
-
N
M
L
G
G
C
P
K
E
R
A
E
I
S
M
L
E
G
A
V
L
D
I
R
Y
G
V
S
R
I
A
Y
S
-
K
D
--
F
E
T
L
K
V
----
D
F
L
S
K
L
P
E
M
L
K
M
F
E
D
-
R
L
C
H
K
T
-
L
N
G
D
H
V
T
H
P
D
F
M
L
Y
D
A
L
D
V
V
L
M
D
P
M
C
L
D
A
F
P
K
L
V
C
---
F
K
K
R
I
E
A
I
P
Q
I
D
K
Y
L
K
-
S
S
K
-
Y
I
A
W
P
L
Q
G
W
Q
A
T
F
G
G
G
D
H
P
P
----------------------------------------------------------------------------
3
PsiBlast_PDB
45.86
27%
37
- C4 -
4LIL
1
PRI1_HUMAN
A:
[274-388]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
H
L
K
K
V
A
S
R
Y
Q
N
N
I
K
NDK
Y
G
P
W
L
E
W
E
I
M
L
Q
Y
C
F
P
-
R
L
D
-
I
N
V
S
K
G
----
I
N
H
L
L
K
S
P
F
S
V
H
P
K
T
G
R
I
S
V
P
I
D
LQKVDQFDPFT
V
P
T
I
S
F
I
C
R
E
L
D
-
A
T
R
D
Y
------
K
K
T
S
L
A
P
Y
V
K
V
F
E
H
F
L
E
N
L
D
K
S
------
6
PsiBlast_PDB
45.58
32%
43
- C4 -
4WR5
2
?
A:
[80-150]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
----
I
D
G
D
V
K
L
T
Q
S
M
A
I
I
R
-
I
A
D
--
K
H
-
N
M
L
G
G
C
P
K
E
R
A
E
I
S
M
L
E
G
A
V
L
D
I
R
Y
G
V
S
R
I
A
Y
S
-
K
D
--
F
E
T
L
K
V
----
D
F
L
S
K
L
P
E
M
L
K
M
F
E
D
-
R
L
C
H
K
T
-
L
N
G
D
H
V
T
H
P
D
F
M
L
Y
D
A
L
D
V
V
L
M
D
P
M
C
L
D
A
F
P
K
L
V
C
---
F
K
K
R
I
E
A
I
P
Q
I
D
K
Y
L
K
-
S
S
K
-
Y
I
A
W
P
L
Q
G
W
Q
A
T
F
G
G
G
D
H
P
P
----------------------------------------------------------------------------
10
PsiBlast_PDB
42.44
32%
43
- C4 -
4AKI
-
DYHC_YEAST (first)
A:
[55-125]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
Y
---
I
D
G
D
V
K
L
T
Q
S
M
A
I
I
R
Y
I
A
D
--
K
H
-
N
M
L
G
G
C
P
K
E
R
A
E
I
S
M
L
E
G
A
V
L
D
I
R
Y
G
V
S
R
I
A
Y
S
-
K
D
--
F
E
T
L
K
V
----
D
F
L
S
K
L
P
E
M
L
K
M
F
E
D
-
R
L
C
H
K
T
-
Y
L
N
G
D
H
V
T
H
P
D
F
M
L
Y
D
A
L
D
V
V
L
Y
M
D
P
M
C
L
D
A
F
P
K
L
---
V
C
F
K
K
R
I
E
A
I
P
Q
I
D
K
Y
-
L
K
S
-
S
K
Y
I
A
W
P
L
Q
G
W
Q
A
T
F
G
G
G
D
H
P
P
F
V
I
E
K
S
L
N
R
I
K
-----------
K
F
W
K
E
A
Q
Y
E
V
I
E
H
S
S
G
L
K
L
V
R
E
W
D
V
L
E
Q
A
C
K
E
D
L
E
E
L
V
S
M
K
A
S
N
Y
Y
K
I
F
E
Q
D
7
PsiBlast_PDB
42.41
32%
47
- C4 -
4AI6
-
DYHC_YEAST (first)
A:
[55-125]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
Y
---
I
D
G
D
V
K
L
T
Q
S
M
A
I
I
R
Y
I
A
D
--
K
H
-
N
M
L
G
G
C
P
K
E
R
A
E
I
S
M
L
E
G
A
V
L
D
I
R
Y
G
V
S
R
I
A
Y
S
-
K
D
--
F
E
T
L
K
V
----
D
F
L
S
K
L
P
E
M
L
K
M
F
E
D
-
R
L
C
H
K
T
-
Y
L
N
G
D
H
V
T
H
P
D
F
M
L
Y
D
A
L
D
V
V
L
Y
M
D
P
M
C
L
D
A
F
P
K
L
---
V
C
F
K
K
R
I
E
A
I
P
Q
I
D
K
Y
-
L
K
S
-
S
K
Y
I
A
W
P
L
Q
G
W
Q
A
T
F
G
G
G
D
H
P
P
F
V
I
E
K
S
L
N
R
I
K
-----------
K
F
W
K
E
A
Q
Y
E
V
I
E
H
S
S
G
L
K
L
V
R
E
W
D
V
L
E
Q
A
C
K
E
D
L
E
E
L
V
S
M
K
A
S
N
Y
Y
K
I
F
E
Q
D
8
PsiBlast_PDB
41.99
32%
44
- C4 -
4AKG
-
DYHC_YEAST (first)
A:
[55-125]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
Y
---
I
D
G
D
V
K
L
T
Q
S
M
A
I
I
R
Y
I
A
D
--
K
H
-
N
M
L
G
G
C
P
K
E
R
A
E
I
S
M
L
E
G
A
V
L
D
I
R
Y
G
V
S
R
I
A
Y
S
-
K
D
--
F
E
T
L
K
V
----
D
F
L
S
K
L
P
E
M
L
K
M
F
E
D
-
R
L
C
H
K
T
-
Y
L
N
G
D
H
V
T
H
P
D
F
M
L
Y
D
A
L
D
V
V
L
Y
M
D
P
M
C
L
D
A
F
P
K
L
---
V
C
F
K
K
R
I
E
A
I
P
Q
I
D
K
Y
-
L
K
S
-
S
K
Y
I
A
W
P
L
Q
G
W
Q
A
T
F
G
G
G
D
H
P
P
F
V
I
E
K
S
L
N
R
I
K
-----------
K
F
W
K
E
A
Q
Y
E
V
I
E
H
S
S
G
L
K
L
V
R
E
W
D
V
L
E
Q
A
C
K
E
D
L
E
E
L
V
S
M
K
A
S
N
Y
Y
K
I
F
E
Q
D
9
PsiBlast_PDB
40.84
32%
45
- C4 -
4AKH
-
DYHC_YEAST (first)
A:
[55-125]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
Y
---
I
D
G
D
V
K
L
T
Q
S
M
A
I
I
R
Y
I
A
D
--
K
H
-
N
M
L
G
G
C
P
K
E
R
A
E
I
S
M
L
E
G
A
V
L
D
I
R
Y
G
V
S
R
I
A
Y
S
-
K
D
--
F
E
T
L
K
V
----
D
F
L
S
K
L
P
E
M
L
K
M
F
E
D
-
R
L
C
H
K
T
-
Y
L
N
G
D
H
V
T
H
P
D
F
M
L
Y
D
A
L
D
V
V
L
Y
M
D
P
M
C
L
D
A
F
P
K
L
---
V
C
F
K
K
R
I
E
A
I
P
Q
I
D
K
Y
-
L
K
S
-
S
K
Y
I
A
W
P
L
Q
G
W
Q
A
T
F
G
G
G
D
H
P
P
F
V
I
E
K
S
L
N
R
I
K
-----------
K
F
W
K
E
A
Q
Y
E
V
I
E
H
S
S
G
L
K
L
V
R
E
W
D
V
L
E
Q
A
C
K
E
D
L
E
E
L
V
S
M
K
A
S
N
Y
Y
K
I
F
E
Q
D
12
HHSearch
40.55
12%
-7
- C4 -
2R1F
8
YCEG_ECOLI
A:
[39-115]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
F
P
L
R
L
V
E
G
M
R
L
S
D
Y
L
K
Q
L
R
E
A
P
Y
I
K
HT
L
S
D
D
K
Y
A
T
V
A
Q
A
L
ELENP
E
W
I
E
G
W
F
W
P
D
T
W
M
Y
T
A
N
T
T
D
V
A
L
L
K
R
A
H
K
K
M
V
K
A
V
D
S
A
W
E
G
R
A
D
G
L
P
Y
K
D
K
N
Q
L
V
T
M
A
S
I
I
E
K
E
T
A
V
A
S
E
R
D
Q
---
V
A
S
V
F
I
N
R
L
R
I
G
M
R
L
Q
T
D
P
--
T
V
I
Y
G
M
G
E
R
Y
N
G
K
L
S
R
A
D
L
E
T
P
T
A
Y
N
T
Y
T
-----
I
T
-
G
L
P
P
G
A
I
A
T
P
----
G
A
D
S
L
K
A
A
A
H
P
A
K
T
P
-
Y
L
Y
F
V
A
-
D
G
K
G
G
H
T
F
N
T
N
L
A
S
H
N
K
S
V
Q
D
Y
L
K
V
L
K
E
K
N
A
Q
---------------------------------------------------------------------------------------------------------------------------
22
Fugue
38.89
10%
105
- C3 -
2PIH
-
YMCA_BACSU
A:
[2-124]
-------------
T
L
Y
S
K
K
D
I
V
Q
Q
A
R
N
L
A
K
M
I
S
E
T
E
E
V
D
F
F
K
R
A
E
A
Q
I
N
E
N
D
K
V
S
T
I
V
N
Q
I
K
A
L
Q
K
---
Q
A
V
N
L
K
H
Y
E
K
H
E
A
L
K
Q
V
E
A
K
I
D
A
L
Q
E
E
L
E
E
I
P
V
I
Q
E
F
R
D
S
Q
M
E
V
N
D
L
L
-
Q
L
V
A
H
T
I
S
N
Q
V
T
N
E
I
I
T
S
T
G
G
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
34.55
25%
76
- C4 -
4MHQ
1
PRI1_HUMAN
A:
[275-354]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
H
L
K
K
V
A
S
R
Y
Q
N
N
I
K
NDK
Y
G
P
W
L
E
W
E
I
M
L
Q
Y
C
F
P
-
R
L
D
-
I
N
V
S
K
G
----
I
N
H
L
L
K
S
P
F
S
V
H
P
K
T
G
R
I
S
V
P
I
D
-----------
L
Q
K
V
D
Q
F
D
P
F
T
V
P
T
I
S
F
I
C
R
E
L
D
A
I
T
R
D
Y
K
K
T
S
L
A
P
Y
V
K
V
F
E
H
F
L
E
N
L
D
K
S
R