@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1689: (2015-12-09 )
MTIKKVLSVTGIILVTVASLAACSSKSHTTKTGKKEVNFATVGTTAPFSYVKDGKLTGFDIEVAKAVFKGSDNYKVTFKKTEWSSVFTGIDSGKFQMGGNNISYSSERSQKYLFSYPIGSTPSVLAVPKNSNIKAYNDITGHKTQVVQGTTTAKQLENFNKKHQKNPVTLKYTNENITQILTNLSDGKADFKLFDGLTVNAIIKNQGLTNLKTIPLTMRDQPYIYFIFGQDQKDLQKYVNNCLKQLRKDGTLSKIAKEYLGGDYVPNEKDLVTPKEK
Atome Classification :
(20 SA)
-.........10........20........30........40.......-.50----.-...-....60........70.---.......80-.-.......90-........100..-..-...110.....------..-..120.......130.--.-...-....140.........150.......160.--......170..---.....180.......190.......200.-..---.....210..--.----..-..-220.....-....--------230.......240.......250.......260.......270.....---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-M
T
I
K
K
V
L
S
V
T
G
I
I
L
V
T
V
A
S
L
A
A
CSSKSHTTKTGK
K
E
V
N
F
A
TVGTTAP
F
-
S
YV----K-DGK-LTG
F
D
I
E
V
A
K
A
V
FKGSD---N
Y
K
V
T
F
K
KT-
E
-
W
S
S
V
FTGID-SG
K
F
QMGGNNISY-SS-ERS
Q
--
K
Y
L
F
S
------YP-IGSTP
S
V
L
A
VPKN--S--N-
I
K
A
-YNDIT--GH
K
T
Q
V
V
QGT
T
T
A
K
Q
L
E
N
F
N
K
K
H--QKN
P
V
T
L
K
YTN---E
N
I
T
Q
I
L
T
NLSDGKA
D
F
K
L
FD
G
L
T
V
N
-
A
I
-
I
K---NQGLTNL
K
T
I
--
P
----
L
T
-MR-D--Q
P
Y
I
Y
-
F
I
FG--------Q
D
Q
K
D
L
Q
K
Y
V
N
N
C
L
K
Q
L
R
KDG
T
L
S
K
I
A
K
E
Y
LGGDYVPNEKDLVTPKEK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
98.25
59%
-94
- C1 -
4C0R
11
?
B:
[3-239]
-----------------------------------
K
T
V
T
L
A
T
V
G
T
T
N
P
F
-
S
Y
E
----
K
-
K
G
K
-
L
T
G
Y
D
I
E
V
A
K
E
V
F
K
A
S
D
---
K
Y
D
V
K
Y
Q
K
T
-
E
-
W
T
S
I
F
S
G
L
D
-
S
D
K
Y
Q
I
G
A
N
N
I
S
Y
-
T
K
-
E
R
A
N
--
K
Y
L
Y
S
------
N
P
-
T
A
S
N
P
L
V
L
V
V
P
K
D
--
S
--
D
-
I
K
S
-
Y
N
D
I
A
--
G
H
S
T
Q
V
V
Q
G
N
T
T
V
P
M
L
Q
K
F
N
K
N
H
--
E
N
N
Q
V
K
L
N
F
T
S
---
E
D
L
A
H
Q
I
R
N
V
S
D
G
K
Y
D
F
K
I
F
E
K
I
S
A
E
-
T
I
-
I
K
---
E
Q
G
L
D
N
L
K
V
I
--
D
----
L
P
-
S
D
-
Q
--
K
P
Y
V
Y
-
F
I
F
A
--------
Q
D
Q
K
D
L
Q
K
F
V
N
K
R
L
K
K
L
Y
E
N
G
T
L
E
K
L
S
K
K
Y
L
G
G
S
Y
L
P
D
K
K
D
M
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
95.95
48%
-93
- C1 -
4EQ9
1
?
A:
[7-245]
----------------------------------
K
K
E
I
I
V
A
T
N
G
S
P
R
P
F
-
I
Y
E
----
E
-
N
G
E
-
L
T
G
Y
E
I
E
V
V
R
A
I
F
K
D
S
D
---
K
Y
D
V
K
F
E
K
T
-
E
-
W
S
G
V
F
A
G
L
D
-
A
D
R
Y
N
M
A
V
N
N
L
S
Y
-
T
K
-
E
R
A
E
--
K
Y
L
Y
A
------
A
P
-
I
A
Q
N
P
N
V
L
V
V
K
K
D
D-
S
--
S
-
I
K
S
-
L
D
D
I
G
--
G
K
S
T
E
V
V
Q
A
T
T
S
A
K
Q
L
E
A
Y
N
A
E
H
--
T
D
N
P
T
I
L
N
Y
T
K
---
A
D
F
Q
Q
I
M
V
R
L
S
D
G
Q
F
D
Y
K
I
F
D
K
I
G
V
E
-
T
V
-
I
K
---
N
Q
G
L
D
N
L
K
V
I
--
E
----
L
P
-
S
D
-
Q
--
Q
P
Y
V
Y
-
P
L
L
A
--------
Q
G
Q
D
E
L
K
S
F
V
D
K
R
I
K
E
L
Y
K
D
G
T
L
E
K
L
S
K
Q
F
F
G
D
T
Y
L
P
A
E
A
D
I
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
69
Fugue
77.36
19%
-74
- C1 -
4P0G
9
MLTF_PSEAE
A:
[7-435]
A
P
T
A
L
E
R
V
Q
K
E
G
V
L
R
V
I
T
R
N
--------------------------
S
P
A
-
T
Y
F
----
Q
-
D
R
N
G
E
T
G
F
E
Y
E
L
A
K
R
F
A
E
R
L
----
G
V
E
L
K
I
E
T
A
-
D
N
L
D
D
L
Y
A
Q
L
S
R
E
G
G
P
A
L
A
A
A
G
L
T
P
-
G
R
-
E
D
D
A
--
S
V
R
Y
S
------
H
T
Y
L
D
V
T
P
Q
I
I
Y
R
N
G
Q
--
Q
--
R
-
P
T
R
-
P
E
D
L
V
--
G
K
R
I
M
V
L
K
G
S
S
H
A
E
Q
L
A
E
L
K
K
Q
Y
--
P
E
----
L
K
Y
E
E
S
DA
V
E
V
V
D
L
L
R
M
V
D
V
G
D
I
D
L
T
L
V
D
S
N
E
L
A
-
M
N
------
Q
V
Y
F
P
N
V
R
V
A
--
F
----
D
F
-
G
E
-
A
--
R
G
L
A
W
-
A
L
P
G
--------
G
D
D
D
S
L
M
N
E
V
N
A
F
L
D
Q
A
K
K
E
G
L
L
Q
R
L
K
D
R
Y
Y
G
H
V
D
V
L
G
Y
V
G
A
Y
T
F
A
Q
H
L
Q
Q
RLPRY
E
S
H
F
K
Q
S
G
K
Q
L
DTD
W
R
L
L
A
A
I
G
Y
Q
E
SLWQPGATSKTGVRGLMMLT
N
R
T
A
Q
A
M
GVSNRLD
P
K
Q
S
I
Q
G
G
S
K
Y
F
V
Q
I
R
S
E
LPESIKE
P
D
R
S
W
F
A
L
A
A
Y
N
IG
G
A
H
L
E
D
A
R
K
M
A
E
K
E
GLNPNK
W
L
D
V
K
K
M
LPRLAQKQWYAKTRYGYAR
G
G
E
T
V
H
F
V
Q
N
V
R
R
Y
Y
D
I
L
T
W
V
T
Q
P
Q
50
HHSearch
74.92
30%
-71
- C1 -
2YLN
10
?
A:
[53-280]
-------------------------------
I
N
N
K
G
T
V
T
V
G
T
E
G
T
Y
A
P
F
-
T
Y
H
----
D
K
D
G
K
-
L
T
G
Y
D
V
E
V
T
R
A
V
A
-
E
K
L
---
G
V
K
V
E
F
K
E
T
-
Q
-
W
D
S
M
M
A
G
L
K
-
A
G
R
F
D
V
V
A
N
Q
V
G
L
T
S
P
-
E
R
Q
A
--
T
F
D
K
S
------
E
P
-
Y
S
W
S
G
A
V
L
V
A
H
N
D
--
S
--
N
-
I
K
S
-
I
A
D
I
K
--
G
V
K
T
A
Q
S
L
T
S
N
Y
G
E
K
A
K
A
A
---------
G
A
Q
L
V
P
V
D
----
G
L
A
Q
S
L
T
L
I
E
Q
K
R
A
D
A
T
L
N
D
E
L
A
V
L
-
D
Y
-
L
K
---
K
N
P
N
A
G
V
K
I
V
--
W
SA--
P
A
-
D
-----
E
K
V
G
S
G
L
I
V
N
--------
K
G
N
D
E
A
V
A
K
F
S
T
A
I
N
E
L
K
A
D
G
T
L
K
K
L
G
E
Q
F
F
G
K
D
I
S
V
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
HHSearch
73.88
24%
-72
- C1 -
2YJP
10
?
A:
[51-279]
-------------------------------
I
K
E
K
G
V
I
R
I
G
V
F
G
D
K
P
P
F
-
G
Y
V
----
D
A
N
G
K
-
N
Q
G
F
D
V
E
I
A
K
D
L
A
-
K
D
L
LGS
P
D
K
V
E
F
V
L
T
-
E
-
A
A
N
R
V
E
Y
V
R
-
S
G
K
V
D
L
I
L
A
N
F
T
Q
-
T
P
-
E
R
A
E
--
A
V
D
F
A
------
D
P
-
Y
M
K
V
A
L
G
V
V
S
P
K
N
--
K
--
P
-
I
T
D
-
M
A
Q
L
K
--
D
Q
T
L
L
V
N
K
G
T
T
A
D
A
F
F
T
K
S
H
P
-------
E
V
K
L
L
K
F
D
----
Q
N
T
E
T
F
D
A
L
K
D
G
R
G
V
A
L
A
H
D
N
A
L
L
W
-
A
W
-
A
K
---
E
N
P
N
--
F
E
V
A
--
I
----
G
N
-
L
G
----
P
A
E
F
I
A
P
A
V
Q
--------
K
G
N
A
D
L
L
N
W
V
N
G
E
I
A
A
M
K
K
D
G
R
L
K
A
A
Y
E
K
T
L
L
P
V
Y
G
E
K
V
K
P
E
A
L
L
A
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
73.59
30%
-77
- C1 -
2Q2C
1
?
A:
[42-262]
-----------------------------------
K
K
V
V
V
G
T
D
A
A
F
A
P
F
-
E
Y
M
----
Q
-
K
G
K
-
I
V
G
F
D
V
D
L
L
D
A
V
M
K
A
A
----
G
L
D
Y
E
L
K
N
I
-
G
-
W
D
P
L
F
A
S
L
Q
-
S
K
E
V
D
M
G
I
S
G
I
T
I
-
T
D
-
E
R
K
Q
--
S
Y
D
F
S
------
D
P
-
Y
F
E
A
T
Q
V
I
L
V
K
Q
G
--
S
--
P
-
V
K
N
-
A
L
D
L
K
--
G
-
K
T
I
G
V
Q
N
A
T
T
G
Q
--
E
A
A
E
K
L
F
--
G
K
G
P
H
I
K
K
F
-----
E
T
T
V
V
A
I
M
E
L
L
N
G
G
V
D
A
V
I
T
D
N
A
V
A
N
-
E
Y
-
V
K
---
N
N
P
N
K
K
L
Q
V
I
E
D
P
----
K
N
-
F
A
-
S
--
E
-
Y
Y
G
-
M
I
F
P
--------
K
N
S
-
E
L
K
A
K
V
D
E
A
L
K
N
V
I
N
S
G
K
Y
T
E
I
Y
K
K
W
F
G
K
E
P
K
L
D
R
L
K
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
HHSearch
72.40
23%
-66
- C1 -
1WDN
1
GLNH_ECOLI
A:
[4-224]
------------------------------------
K
L
V
V
A
T
D
T
A
F
V
P
F
-
E
F
K
----
Q
-
G
D
L
-
Y
V
G
F
D
V
D
L
W
A
A
I
A
-
K
E
L
---
K
L
D
Y
E
L
K
P
M
-
D
-
F
S
G
I
I
P
A
L
Q
-
T
K
N
V
D
L
A
L
A
G
I
T
I
-
T
D
-
E
R
K
K
--
A
I
D
F
S
------
D
G
-
Y
Y
K
S
G
L
L
V
M
V
K
A
N
N-
N
--
D
-
V
K
S
-
V
K
D
L
D
--
G
K
V
V
A
V
K
S
G
T
G
S
V
D
Y
A
K
A
N
I
K
-------
T
K
D
L
R
Q
F
P
----
N
I
D
N
A
Y
M
E
L
G
T
N
R
A
D
A
V
L
H
D
T
P
N
I
L
-
Y
F
-
I
K
---
T
A
G
N
G
Q
F
K
A
V
--
G
----
D
S
-
L
-----
E
A
Q
Q
Y
G
I
A
F
P
--------
K
G
S
D
E
L
R
D
K
V
N
G
A
L
K
T
L
R
E
N
G
T
Y
N
E
I
Y
K
K
W
F
G
T
E
P
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
61
HHSearch
72.28
21%
-67
* C1 *
3VV5
1
?
A:
[32-256]
-------------------------------
I
K
R
S
G
E
I
R
I
G
T
E
G
A
F
P
P
F
-
N
Y
F
----
D
E
R
N
Q
-
L
T
G
F
E
V
D
L
G
N
A
I
A
-
E
R
L
---
G
L
K
P
R
W
I
A
Q
-
S
-
F
D
T
L
L
I
Q
L
N
-
Q
G
R
F
D
F
V
I
A
S
H
G
I
-
T
E
-
E
R
A
R
--
A
V
D
F
T
------
N
P
-
H
Y
C
T
G
G
V
I
V
S
R
K
G
--
G
----
P
R
T
-
A
K
D
L
Q
--
G
K
V
V
G
V
Q
V
G
T
T
Y
M
E
A
A
Q
K
I
P
G
-------
I
K
E
V
R
T
Y
Q
----
R
D
P
D
A
L
Q
D
L
L
A
G
R
I
D
T
W
I
T
D
R
F
V
A
K
-
E
A
-
I
K
---
E
R
K
L
E
N
T
L
Q
V
--
G
----
E
L
-
V
-----
F
Q
E
R
V
A
M
A
V
A
--------
K
G
N
K
S
L
L
D
A
L
N
R
A
L
A
E
L
M
Q
D
G
T
Y
A
R
I
S
Q
K
W
F
G
E
D
V
R
C
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
72.07
30%
-77
- C1 -
2PVU
3
?
A:
[41-262]
----------------------------------
K
K
K
V
V
V
G
T
D
A
A
F
A
P
F
-
E
Y
M
----
Q
-
K
G
K
-
I
V
G
F
D
V
D
L
L
D
A
V
M
K
A
A
----
G
L
D
Y
E
L
K
N
I
-
G
-
W
D
P
L
F
A
S
L
Q
-
S
K
E
V
D
M
G
I
S
G
I
T
I
-
T
D
-
E
R
K
Q
--
S
Y
D
F
S
------
D
P
-
Y
F
E
A
T
Q
V
I
L
V
K
Q
G
--
S
--
P
-
V
K
N
-
A
L
D
L
K
--
G
-
K
T
I
G
V
Q
N
A
T
T
G
Q
--
E
A
A
E
K
L
F
--
G
K
G
P
H
I
K
K
F
-----
E
T
T
V
V
A
I
M
E
L
L
N
G
G
V
D
A
V
I
T
D
N
A
V
A
N
-
E
Y
-
V
K
---
N
N
P
N
K
K
L
Q
V
I
E
D
P
----
K
N
-
F
A
-
S
--
E
-
Y
Y
G
-
M
I
F
P
--------
K
N
S
-
E
L
K
A
K
V
D
E
A
L
K
N
V
I
N
S
G
K
Y
T
E
I
Y
K
K
W
F
G
K
E
P
K
L
D
R
L
K
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
HHSearch
71.99
26%
-76
- C1 -
2PVU
4
?
A:
[38-266]
-------------------------------
G
A
T
K
K
K
V
V
V
G
T
D
A
A
F
A
P
F
-
E
Y
M
----
Q
-
K
G
K
-
I
V
G
F
D
V
D
L
L
D
A
V
M
-
K
A
A
---
G
L
D
Y
E
L
K
N
I
-
G
-
W
D
P
L
F
A
S
L
Q
-
S
K
E
V
D
M
G
I
S
G
I
T
I
-
T
D
-
E
R
K
Q
--
S
Y
D
F
S
------
D
P
-
Y
F
E
A
T
Q
V
I
L
V
K
Q
G
--
S
--
P
-
V
K
N
-
A
L
D
L
K
--
G
K
T
I
G
V
Q
N
A
T
T
G
Q
E
A
A
E
K
L
F
G
K
------
G
P
H
I
K
K
F
E
----
T
T
V
V
A
I
M
E
L
L
N
G
G
V
D
A
V
I
T
D
N
A
V
A
N
-
E
Y
-
V
K
---
N
N
P
N
K
K
L
Q
V
I
--
E
----
D
P
K
N
F
----
A
S
E
Y
Y
G
M
I
F
P
--------
K
-
N
S
E
L
K
A
K
V
D
E
A
L
K
N
V
I
N
S
G
K
Y
T
E
I
Y
K
K
W
F
G
K
E
P
K
L
D
R
L
K
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
71.77
30%
-75
- C1 -
2Q2A
1
?
A:
[41-262]
----------------------------------
K
K
K
V
V
V
G
T
D
A
A
F
A
P
F
-
E
Y
M
----
Q
-
K
G
K
-
I
V
G
F
D
V
D
L
L
D
A
V
M
K
A
A
----
G
L
D
Y
E
L
K
N
I
-
G
-
W
D
P
L
F
A
S
L
Q
-
S
K
E
V
D
M
G
I
S
G
I
T
I
-
T
D
-
E
R
K
Q
--
S
Y
D
F
S
------
D
P
-
Y
F
E
A
T
Q
V
I
L
V
K
Q
G
--
S
--
P
-
V
K
N
-
A
L
D
L
K
--
G
-
K
T
I
G
V
Q
N
A
T
T
G
Q
--
E
A
A
E
K
L
F
--
G
K
G
P
H
I
K
K
F
-----
E
T
T
V
V
A
I
M
E
L
L
N
G
G
V
D
A
V
I
T
D
N
A
V
A
N
-
E
Y
-
V
K
---
N
N
P
N
K
K
L
Q
V
I
E
D
P
----
K
N
-
F
A
-
S
--
E
-
Y
Y
G
-
M
I
F
P
--------
K
N
S
-
E
L
K
A
K
V
D
E
A
L
K
N
V
I
N
S
G
K
Y
T
E
I
Y
K
K
W
F
G
K
E
P
K
L
D
R
L
K
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
53
HHSearch
71.59
22%
-58
- C1 -
1LST
1
ARGT_SALTY
A:
[2-234]
---------------------------------
L
P
Q
T
V
R
I
G
T
D
T
T
Y
A
P
F
-
S
S
K
----
D
A
K
G
E
-
F
I
G
F
D
I
D
L
G
N
E
M
C
-
K
R
M
---
Q
V
K
C
T
W
V
A
S
-
D
-
F
D
A
L
I
P
S
L
K
-
A
K
K
I
D
A
I
I
S
S
L
S
I
-
T
D
-
K
R
Q
Q
--
E
I
A
F
S
------
D
K
-
L
Y
A
A
D
S
R
L
I
A
A
K
G
--
S
--
P
I
Q
P
T
-
L
E
S
L
K
--
G
K
H
V
G
V
L
Q
G
S
T
Q
E
A
Y
A
N
D
N
W
R
T
-----
K
G
V
D
V
V
A
Y
A
----
N
Q
D
L
I
Y
S
D
L
T
A
G
R
L
D
A
A
L
Q
D
E
V
A
A
S
-
E
G
F
L
K
---
Q
P
A
G
K
E
Y
A
F
A
--
G
----
P
S
-
V
K
D
K
KY
F
G
D
G
T
G
V
G
L
R
--------
K
D
D
T
E
L
K
A
A
F
D
K
A
L
T
E
L
R
Q
D
G
T
Y
D
K
M
A
K
K
Y
F
D
F
N
V
Y
G
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
71.04
32%
-57
- C1 -
2YLN
10
?
A:
[56-279]
----------------------------------
K
G
T
V
T
V
G
T
E
G
T
Y
A
P
F
-
T
Y
H
D
---
K
-
D
G
K
-
L
T
G
Y
D
V
E
V
T
R
A
V
A
E
K
L
----
G
V
K
V
E
F
K
E
T
-
Q
-
W
D
S
M
M
A
G
L
K
-
A
G
R
F
D
V
V
A
N
Q
V
G
L
-
T
S
P
E
R
Q
A
--
T
F
D
K
S
------
E
P
-
Y
S
W
S
G
A
V
L
V
A
H
N
D
--
S
--
N
-
I
K
S
-
I
A
D
I
K
--
G
V
K
T
--
A
Q
S
L
T
S
-----
N
Y
G
E
K
A
--
K
A
A
G
A
Q
L
-
V
P
V
---
D
G
L
A
Q
S
L
T
L
I
E
Q
K
R
A
D
A
T
L
N
D
E
L
A
V
L
-
D
Y
-
L
K
K
N
P
N
A
G
V
K
I
V
W
S
A
--
P
----
A
D
-
E
K
-
V
--
G
S
G
L
I
-
V
N
K
G
--------
N
D
E
A
-
V
A
K
F
-
S
T
A
I
N
E
L
K
A
D
G
T
L
K
K
L
G
E
Q
F
F
G
K
D
I
S
V
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
HHSearch
70.99
21%
-81
- C1 -
3H7M
1
?
A:
[7-231]
-------------------------------
R
D
R
H
R
T
I
V
V
G
G
D
R
D
Y
P
P
Y
-
E
F
I
----
D
Q
N
G
K
-
P
A
G
Y
N
V
E
L
T
R
A
I
A
-
E
V
M
---
G
M
T
V
E
F
R
L
G
-
A
-
W
S
E
M
F
S
A
L
K
-
S
G
R
V
D
V
L
Q
-
G
I
S
W
-
S
E
-
K
R
A
R
--
Q
I
D
F
T
------
P
P
-
H
T
I
V
Y
H
A
I
F
A
R
R
D
S-
P
--
P
-
A
A
G
-
L
E
D
L
R
--
G
R
K
V
A
L
H
R
D
G
I
M
H
E
Y
L
A
E
R
G
Y
-------
G
K
D
L
V
L
T
P
----
T
P
A
D
A
L
R
L
L
A
A
G
G
C
D
Y
A
V
V
A
M
V
P
G
M
-
Y
I
-
I
R
---
E
N
R
L
T
N
L
V
P
V
--
A
----
R
S
-
I
-----
A
A
Q
R
Y
G
Y
A
V
R
--------
Q
G
D
A
E
L
L
A
R
F
S
E
G
L
A
I
L
R
K
T
G
Q
Y
E
A
I
R
A
K
W
L
G
V
L
E
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
57
HHSearch
70.71
20%
-73
- C1 -
2Y7I
7
?
A:
[4-228]
---------------------------------
S
A
R
T
L
H
F
G
T
S
A
T
Y
A
P
Y
-
E
F
V
----
D
A
D
N
K
-
I
V
G
F
D
I
D
V
A
N
A
V
C
-
K
E
M
---
Q
A
E
C
S
F
T
N
Q
-
S
-
F
D
S
L
I
P
S
L
R
-
F
K
K
F
D
A
V
I
A
G
M
D
M
-
T
P
-
K
R
E
Q
--
Q
V
S
F
S
------
Q
P
-
Y
Y
E
G
L
S
A
V
V
V
T
R
K
--
G
--
A
-
Y
H
T
-
F
A
D
L
K
--
G
K
K
V
G
L
E
N
G
T
T
H
Q
R
Y
L
Q
D
K
Q
Q
-------
A
I
T
P
V
A
Y
D
----
S
Y
L
N
A
F
T
D
L
K
N
N
R
L
E
G
V
F
G
D
V
A
A
I
G
-
K
W
-
L
K
---
N
N
P
D
--
Y
A
I
M
--
D
E
R
A
S
D
P
-
D
Y
----
Y
G
K
G
L
G
I
A
V
R
--------
K
D
N
D
A
L
L
Q
E
I
N
A
A
L
D
K
V
K
A
S
P
E
Y
A
Q
M
Q
E
K
W
F
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
69.67
25%
-51
- C1 -
1HSL
6
HISJ_ECOLI
A:
[4-234]
-----------------------------------
Q
K
I
R
I
G
T
D
P
T
Y
A
P
F
E
S
K
N
----
A
-
Q
G
E
-
L
V
G
F
D
I
D
L
A
K
E
L
C
K
-
R
I
---
N
T
Q
C
T
F
V
E
N
-
P
-
L
D
A
L
I
P
S
L
K
-
A
K
K
I
D
A
I
M
S
S
L
S
I
-
T
E
-
K
R
Q
Q
--
E
I
A
F
T
------
D
K
-
L
Y
A
A
D
S
R
L
V
V
A
K
N
--
S
--
D
-
I
Q
P
T
V
A
S
L
K
--
G
K
R
V
G
V
L
Q
G
T
T
Q
----
E
T
F
G
N
E
H
WA
P
K
G
I
E
I
V
S
Y
Q
G
---
Q
D
--
N
I
Y
S
D
L
T
A
G
R
I
D
A
A
F
Q
D
E
V
A
A
S
E
G
F
-
L
K
---
Q
P
V
G
K
D
Y
K
F
G
--
G
----
P
A
-
V
K
-
D
--
E
K
-----
L
F
G
V
G
T
G
M
G
L
R
K
E
D
N
E
L
R
E
A
L
N
K
A
F
A
E
M
R
A
D
G
T
Y
E
K
L
A
K
K
Y
F
D
F
D
V
Y
G
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
69.44
32%
-63
- C1 -
3ZSF
-
?
A:
[48-271]
----------------------------------
K
G
T
V
T
V
G
T
E
G
T
Y
A
P
F
-
T
Y
H
D
---
K
-
D
G
K
-
L
T
G
Y
D
V
E
V
T
R
A
V
A
E
K
L
----
G
V
K
V
E
F
K
E
T
-
Q
-
W
D
S
M
M
A
G
L
K
-
A
G
R
F
D
V
V
A
N
Q
V
G
L
-
T
S
P
E
R
Q
A
--
T
F
D
K
S
------
E
P
-
Y
S
W
S
G
A
V
L
V
A
H
N
D
--
S
--
N
-
I
K
S
-
I
A
D
I
K
--
G
V
K
T
--
A
Q
S
L
T
S
-----
N
Y
G
E
K
A
--
K
A
A
G
A
Q
L
-
V
P
V
---
D
G
L
A
Q
S
L
T
L
I
E
Q
K
R
A
D
A
T
L
N
D
E
L
A
V
L
-
D
Y
-
L
K
K
N
P
N
A
G
V
K
I
V
W
S
A
--
P
----
A
D
-
E
K
-
V
--
G
S
G
L
I
-
V
N
K
G
--------
N
D
E
A
-
V
A
K
F
-
S
T
A
I
N
E
L
K
A
D
G
T
L
K
K
L
G
E
Q
F
F
G
K
D
I
S
V
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
59
HHSearch
69.17
20%
-65
- C1 -
3KBR
10
PHEC_PSEAE
A:
[11-236]
-------------------------------
I
L
E
S
G
V
L
R
V
A
T
T
G
D
Y
K
P
F
-
S
Y
R
----
T
E
E
G
G
-
Y
A
G
F
D
V
D
M
A
Q
R
L
A
-
E
S
L
---
G
A
K
L
V
V
V
P
T
-
S
-
W
P
N
L
M
R
D
F
A
-
D
D
R
F
D
I
A
M
S
G
I
S
I
-
N
L
-
E
R
Q
R
--
Q
A
Y
F
S
------
I
P
-
Y
L
R
D
G
K
T
P
I
T
L
C
S
EE
A
--
R
-
F
Q
T
-
L
E
Q
I
D
QP
G
V
T
A
I
V
N
P
G
G
T
N
E
K
F
A
R
A
N
L
K
-------
K
A
R
I
L
V
H
P
----
D
N
V
T
I
F
Q
Q
I
V
D
G
K
A
D
L
M
M
T
D
A
I
E
A
R
-
L
Q
-
S
R
---
L
H
P
E
L
C
-
A
V
H
--
P
----
Q
P
-
F
D
-----
F
A
E
K
A
Y
L
L
P
--------
R
-
D
E
A
F
K
R
Y
V
D
Q
W
L
H
I
A
E
Q
S
G
L
L
R
Q
R
M
E
H
W
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
68.82
25%
-74
- C1 -
2O1M
3
TCYK_BACSU
A:
[14-245]
------------------------------------
K
V
Q
T
I
T
V
G
T
G
T
Q
F
-
P
N
I
C
F
I
D
E
-
K
G
D
-
L
T
G
Y
D
V
E
L
I
K
E
L
D
K
R
L
P
---
H
Y
K
F
T
F
K
T
M
-
E
-
F
S
N
L
L
V
S
L
G
-
Q
H
K
V
D
I
V
A
H
Q
M
E
K
-
S
K
-
E
R
E
K
--
K
F
L
F
N
KVAY
N
H
F
P
-
L
----
K
I
T
V
L
Q
N
N
--
D
--
T
-
I
R
G
-
I
E
D
L
K
--
G
K
R
V
I
T
S
A
T
S
N
G
A
L
V
L
K
K
W
N
E
D
N
--
G
R
-
P
F
E
I
A
Y
E
G
---
Q
G
A
N
E
T
A
N
Q
L
K
S
G
R
A
D
A
T
I
S
T
P
F
A
V
D
-
F
Q
-
N
K
---
T
S
T
I
K
E
-
K
T
V
--
G
----
N
V
-
L
S
-
N
--
A
K
-
V
Y
-
F
M
F
N
--------
K
N
E
Q
T
L
S
D
D
I
D
K
A
L
Q
E
I
I
D
D
G
T
L
K
R
L
S
L
K
W
L
G
D
D
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
62
HHSearch
68.79
21%
-86
- C1 -
1II5
1
?
A:
[3-226]
----------------------------------
A
M
A
L
K
V
G
V
V
-
G
N
P
P
F
-
V
F
Y
----
G
---
A
-
F
T
G
I
S
L
D
V
W
R
A
V
A
-
E
S
Q
---
K
W
N
S
E
Y
V
R
Q
N
S
-
I
S
A
G
I
T
A
V
A
-
E
G
E
L
D
I
L
I
G
P
I
S
V
-
T
P
-
E
R
A
A
IE
G
I
T
F
T
------
Q
P
-
Y
F
S
S
G
I
G
L
L
I
P
G
T
--
A
TP
L
-
F
R
S
-
V
G
D
L
K
--
N
K
E
V
A
V
V
R
D
T
T
A
V
D
W
A
N
F
---------
Y
Q
A
D
V
R
E
T
N
----
N
L
T
A
A
I
T
L
L
Q
K
K
Q
V
E
A
V
M
F
D
R
P
A
L
I
-
Y
Y
-
T
R
---
Q
N
P
N
L
N
L
E
V
T
--
E
----
I
R
-
V
-----
S
L
E
P
Y
G
F
V
L
K
--------
E
N
-
S
P
L
Q
K
T
I
N
V
E
M
L
N
L
L
Y
S
R
V
I
A
E
F
T
E
R
W
L
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------