@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1760: (2015-12-10 )
MWPEDRIASFRRTLLGWYDQEKRDLPWRRTTNPYYIWVSEIMLQQTQVNTVIPYYKRFLEWFPQIKDLADAPEEQLLKAWEGLGYYSRVRNMQKAAQQVMVDFGGIFPHTYDDIASLKGIGPYTAGAIASISFNLPEPAVDGNVMRVMARLFEVNYDIGDPKNRKIFQAIMEILIDPDRPGDFNQALMDLGTDIESAKTPRPDESPIRFFNAAYLNGTYSKYPIKNPKKKPKPMRIQAFVIRNQNGQYLLEKNTKGRLLGGFWSFPIIETSPLSQQLDLFDDNQSNPIIWQTQNETFQREYQLKPQWTDNHFPNIKHTFSHQKWTIELIEGVVKATDLPNAPHLKWAAIEDFSLYPFATPQKKMLETYLKQKNA
Atome Classification :
(24 SA)
.........10........20...-......30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MW
P
E
D
R
I
A
S
F
R
R
T
L
L
G
W
YDQ-EKR-DLPWRRTTN
P
Y
Y
I
W
V
S
E
I
M
L
Q
QTQVN
T
V
I
P
Y
Y
K
R
F
L
E
W
F
P
Q
I
K
D
L
ADA
P
E
E
Q
L
L
K
A
W
EGL
G
Y
Y
S
R
V
R
N
M
Q
K
A
A
Q
Q
V
M
V
D
FGGIFPH
T
Y
D
D
I
A
SLKGIGPYTAG
A
I
A
S
I
S
FNLPEPAVD
G
N
V
M
R
V
M
A
R
L
F
EVNYDIGDPKN
R
K
I
F
Q
A
I
M
E
I
LIDPDRPG
D
F
N
Q
A
L
M
D
LGTDIESAKTPRPDESP
I
R
F
F
N
A
A
Y
LNGTYSKYPIKNPKKKPK
P
M
R
I
Q
A
F
V
I
RNQNG
Q
Y
L
L
EKNTKG
R
L
L
G
G
FWSFPIIETSP
L
S
Q
Q
LDLFDDNQSN
P
I
I
W
QTQN
E
T
F
Q
R
E
YQLKPQWTDNHFPN
I
K
H
TFSHQ
K
W
T
I
E
L
I
E
G
V
V
K
ATDLPNAPH
L
K
W
A
A
IEDFSLYPFAT
P
Q
K
K
M
L
E
T
Y
L
K
QKNA
4
PsiBlast_PDB
93.98
37%
-85
- C2 -
3G0Q
4
?
A:
[5-347]
---------
F
Q
R
D
L
L
D
W
F
A
R
-
E
R
R
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L
P
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C
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A
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A
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M
----
V
K
Q
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P
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A
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A
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----------
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G
A
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K
L
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Q
M
V
--------
G
L
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V
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T
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A
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-
R
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A
F
P
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S
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Q
R
V
W
R
E
Y
K
E
W
A
S
-
25
HHSearch
93.23
37%
-82
* C2 *
3FSP
4
?
A:
[11-361]
----
F
P
A
R
E
F
Q
R
D
L
L
D
W
F
A
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-
E
R
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L
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A
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A
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A
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L
K
A
W
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G
L
G
Y
Y
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R
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R
N
L
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A
A
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G
G
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R
P
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Q
A
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C
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A
F
A
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A
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M
K
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A
V
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K
R
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L
L
A
N
L
W
E
F
P
S
C
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T
D
-
G
A
D
G
K
E
-------------
K
L
E
Q
M
V
G
E
Q
Y
G
L
Q
V
E
L
-
T
E
P
I
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F
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H
A
F
S
H
L
V
W
Q
L
T
V
F
P
G
R
L
V
H
G
-
G
P
V
E
E
P
Y
R
L
A
P
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K
A
Y
A
F
P
V
S
H
Q
R
V
W
R
E
Y
K
E
W
A
S
-
6
PsiBlast_PDB
93.10
37%
-87
- C2 -
4YPH
4
?
A:
[16-358]
---------
F
Q
R
D
L
L
D
W
F
A
R
-
E
R
R
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L
P
W
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A
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A
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A
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L
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Y
Y
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N
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A
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A
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N
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A
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I
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L
G
A
L
V
C
T
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R
P
S
C
L
L
C
P
V
Q
A
Y
C
Q
A
F
A
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G
V
A
E
E
L
P
V
K
M
----
V
K
Q
V
P
L
A
V
A
V
L
A
D
D
E
G
R
V
L
I
R
K
R
D
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T
G
L
L
A
N
L
W
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F
P
S
C
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T
----------
D
G
A
D
G
K
E
K
L
E
Q
M
V
--------
G
L
Q
V
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-
I
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A
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P
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W
R
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Y
K
E
W
A
S
-
7
PsiBlast_PDB
92.31
37%
-84
- C2 -
1RRQ
4
?
A:
[16-358]
---------
F
Q
R
D
L
L
D
W
F
A
R
-
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R
R
-
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L
P
W
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A
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A
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A
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L
G
Y
Y
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A
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G
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A
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L
G
A
L
V
C
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R
R
P
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C
L
L
C
P
V
Q
A
Y
C
Q
A
F
A
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G
V
A
E
E
L
P
V
K
M
----
V
K
Q
V
P
L
A
V
A
V
L
A
D
D
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G
R
V
L
I
R
K
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D
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T
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L
L
A
N
L
W
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F
P
S
C
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----------
D
G
A
D
G
K
E
K
L
E
Q
M
V
--------
G
L
Q
V
E
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T
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P
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I
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A
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A
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A
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P
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H
Q
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W
R
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Y
K
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A
S
-
3
PsiBlast_PDB
91.83
37%
-82
- C2 -
1VRL
5
?
A:
[16-358]
---------
F
Q
R
D
L
L
D
W
F
A
R
-
E
R
R
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L
P
W
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----------
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--
D
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K
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K
L
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--------
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W
R
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K
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A
S
-
48
Fugue
91.75
36%
-76
- C2 -
1RRQ
4
?
A:
[12-362]
-----
P
A
R
E
F
Q
R
D
L
L
D
W
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A
R
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N
P
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A
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N
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A
L
I
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L
G
A
L
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C
T
P
R
R
P
S
C
L
L
C
P
V
Q
A
Y
C
Q
A
F
A
E
G
V
A
E
E
L
P
----
V
K
M
V
K
Q
V
P
L
A
V
A
V
L
A
D
D
E
G
R
V
L
I
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K
R
D
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T
G
L
L
A
N
L
W
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F
P
S
C
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D
G
-------------------
A
D
G
K
E
K
L
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G
L
Q
V
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L
T
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I
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F
E
H
A
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L
V
W
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F
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H
G
G
P
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E
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A
F
P
V
S
H
Q
R
V
W
R
E
Y
K
E
W
A
S
-
5
PsiBlast_PDB
91.59
37%
-84
- C2 -
4YOQ
5
?
A:
[16-358]
---------
F
Q
R
D
L
L
D
W
F
A
R
-
E
R
R
-
D
L
P
W
R
K
D
R
D
P
Y
K
V
W
V
S
E
V
M
L
Q
Q
T
R
V
E
T
V
I
P
Y
F
E
Q
F
I
D
R
F
P
T
L
E
A
L
A
D
A
D
E
D
E
V
L
K
A
W
E
G
L
G
Y
Y
S
R
V
R
N
L
H
A
A
V
K
E
V
K
T
R
Y
G
G
K
V
P
D
D
P
D
E
F
S
R
L
K
G
V
G
P
Y
T
V
G
A
V
L
S
L
A
Y
G
V
P
E
P
A
V
D
G
N
V
M
R
V
L
S
R
L
F
L
V
T
D
D
I
A
K
C
S
T
R
K
R
F
E
Q
I
V
R
E
I
M
A
Y
E
N
P
G
A
F
N
E
A
L
I
E
L
G
A
L
V
C
T
P
R
R
P
S
C
L
L
C
P
V
Q
A
Y
C
Q
A
F
A
E
G
V
A
E
E
L
P
V
K
M
----
V
K
Q
V
P
L
A
V
A
V
L
A
D
D
E
G
R
V
L
I
R
K
R
D
S
T
G
L
L
A
N
L
W
E
F
P
S
C
E
T
----------
D
G
A
D
G
K
E
K
L
E
Q
M
V
--------
G
L
Q
V
E
L
T
E
P
-
I
V
S
F
E
H
A
F
S
H
L
V
W
Q
L
T
V
F
P
G
R
L
V
H
G
G
P
V
E
E
P
Y
-
R
L
A
P
E
D
E
L
K
A
Y
A
F
P
V
S
H
Q
R
V
W
R
E
Y
K
E
W
A
S
-
21
PsiBlast_CBE
91.47
37%
-80
- C2 -
4YPR
3
?
B:
[16-358]
---------
F
Q
R
D
L
L
D
W
F
A
R
-
E
R
R
-
D
L
P
W
R
K
D
R
D
P
Y
K
V
W
V
S
E
V
M
L
Q
Q
T
R
V
E
T
V
I
P
Y
F
E
Q
F
I
D
R
F
P
T
L
E
A
L
A
D
A
D
E
D
E
V
L
K
A
W
E
G
L
G
Y
Y
S
R
V
R
N
L
H
A
A
V
K
E
V
K
T
R
Y
G
G
K
V
P
D
D
P
D
E
F
S
R
L
K
G
V
G
P
Y
T
V
G
A
V
L
S
L
A
Y
G
V
P
E
P
A
V
N
G
N
V
M
R
V
L
S
R
L
F
L
V
T
D
D
I
A
K
C
S
T
R
K
R
F
E
Q
I
V
R
E
I
M
A
Y
E
N
P
G
A
F
N
E
A
L
I
E
L
G
A
L
V
C
T
P
R
R
P
S
C
L
L
C
P
V
Q
A
Y
C
Q
A
F
A
E
G
V
A
E
E
L
P
V
K
M
K
K
T
A
V
K
Q
V
P
L
A
V
A
V
L
A
D
D
E
G
R
V
L
I
R
K
R
D
S
T
G
L
L
A
N
L
W
E
F
P
S
C
E
T
----------
D
G
A
D
G
K
E
K
L
E
Q
M
V
G
---------
Q
V
E
L
T
E
P
-
I
V
S
F
E
H
A
F
S
H
L
V
W
Q
L
T
V
F
P
G
R
L
V
H
G
G
P
V
E
E
P
Y
-
R
L
A
P
E
D
E
L
K
A
Y
A
F
P
V
S
H
Q
R
V
W
R
E
Y
K
E
W
A
S
-
8
PsiBlast_PDB
91.42
37%
-79
- C2 -
4YPR
5
?
A:
[16-358]
---------
F
Q
R
D
L
L
D
W
F
A
R
-
E
R
R
-
D
L
P
W
R
K
D
R
D
P
Y
K
V
W
V
S
E
V
M
L
Q
Q
T
R
V
E
T
V
I
P
Y
F
E
Q
F
I
D
R
F
P
T
L
E
A
L
A
D
A
D
E
D
E
V
L
K
A
W
E
G
L
G
Y
Y
S
R
V
R
N
L
H
A
A
V
K
E
V
K
T
R
Y
G
G
K
V
P
D
D
P
D
E
F
S
R
L
K
G
V
G
P
Y
T
V
G
A
V
L
S
L
A
Y
G
V
P
E
P
A
V
N
G
N
V
M
R
V
L
S
R
L
F
L
V
T
D
D
I
A
K
C
S
T
R
K
R
F
E
Q
I
V
R
E
I
M
A
Y
E
N
P
G
A
F
N
E
A
L
I
E
L
G
A
L
V
C
T
P
R
R
P
S
C
L
L
C
P
V
Q
A
Y
C
Q
A
F
A
E
G
V
A
E
E
L
P
V
K
M
K
K
T
A
V
K
Q
V
P
L
A
V
A
V
L
A
D
D
E
G
R
V
L
I
R
K
R
D
S
T
G
L
L
A
N
L
W
E
F
P
S
C
E
T
----------
D
G
A
D
G
K
E
K
L
E
Q
M
V
G
E
----
Q
Y
G
L
Q
V
E
L
T
E
P
-
I
V
S
F
E
H
A
F
S
H
L
V
W
Q
L
T
V
F
P
G
R
L
V
H
G
G
P
V
E
E
P
Y
-
R
L
A
P
E
D
E
L
K
A
Y
A
F
P
V
S
H
Q
R
V
W
R
E
Y
K
E
W
A
S
-
2
PsiBlast_PDB
91.16
37%
-82
- C2 -
1RRS
4
?
A:
[16-358]
---------
F
Q
R
D
L
L
D
W
F
A
R
-
E
R
R
-
D
L
P
W
R
K
D
R
D
P
Y
K
V
W
V
S
E
V
M
L
Q
Q
T
R
V
E
T
V
I
P
Y
F
E
Q
F
I
D
R
F
P
T
L
E
A
L
A
D
A
D
E
D
E
V
L
K
A
W
E
G
L
G
Y
Y
S
R
V
R
N
L
H
A
A
V
K
E
V
K
T
R
Y
G
G
K
V
P
D
D
P
D
E
F
S
R
L
K
G
V
G
P
Y
T
V
G
A
V
L
S
L
A
Y
G
V
P
E
P
A
V
N
G
N
V
M
R
V
L
S
R
L
F
L
V
T
D
D
I
A
K
P
S
T
R
K
R
F
E
Q
I
V
R
E
I
M
A
Y
E
N
P
G
A
F
N
E
A
L
I
E
L
G
A
L
V
C
T
P
R
R
P
S
C
L
L
C
P
V
Q
A
Y
C
Q
A
F
A
E
G
V
A
E
E
L
P
V
K
M
K
---
V
K
Q
V
P
L
A
V
A
V
L
A
D
D
E
G
R
V
L
I
R
K
R
D
S
T
G
L
L
A
N
L
W
E
F
P
S
C
E
T
----------
D
G
A
D
G
K
E
K
L
E
Q
M
V
--------
G
L
Q
V
E
L
T
E
P
-
I
V
S
F
E
H
A
F
S
H
L
V
W
Q
L
T
V
F
P
G
R
L
V
H
G
G
P
V
E
E
P
Y
-
R
L
A
P
E
D
E
L
K
A
Y
A
F
P
V
S
H
Q
R
V
W
R
E
Y
K
E
W
A
S
-
1
PsiBlast_PDB
90.82
37%
-80
- C2 -
3FSP
4
?
A:
[16-358]
---------
F
Q
R
D
L
L
D
W
F
A
R
-
E
R
R
-
D
L
P
W
R
K
D
R
D
P
Y
K
V
W
V
S
E
V
M
L
Q
Q
T
R
V
E
T
V
I
P
Y
F
E
Q
F
I
D
R
F
P
T
L
E
A
L
A
D
A
D
E
D
E
V
L
K
A
W
E
G
L
G
Y
Y
S
R
V
R
N
L
H
A
A
V
K
E
V
K
T
R
Y
G
G
K
V
P
D
D
P
D
E
F
S
R
L
K
G
V
G
P
Y
T
V
G
A
V
L
S
L
A
Y
G
V
P
E
P
A
V
D
G
N
V
M
R
V
L
S
R
L
F
L
V
T
D
D
I
A
K
P
S
T
R
K
R
F
E
Q
I
V
R
E
I
M
A
Y
E
N
P
G
A
F
N
E
A
L
I
E
L
G
A
L
V
C
T
P
R
R
P
S
C
L
L
C
P
V
Q
A
Y
C
Q
A
F
A
E
G
V
A
E
E
L
P
V
K
M
K
K
T
A
V
K
Q
V
P
L
A
V
A
V
L
A
D
D
E
G
R
V
L
I
R
K
R
D
S
T
G
L
L
A
N
L
W
E
F
P
S
C
E
T
----------
D
G
A
D
G
K
E
K
L
E
Q
M
V
G
E
----
Q
Y
G
L
Q
V
E
L
T
E
P
-
I
V
S
F
E
H
A
F
S
H
L
V
W
Q
L
T
V
F
P
G
R
L
V
H
G
G
P
V
E
E
P
Y
-
R
L
A
P
E
D
E
L
K
A
Y
A
F
P
V
S
H
Q
R
V
W
R
E
Y
K
E
W
A
S
-
16
PsiBlast_PDB
79.29
43%
-89
- C2 -
1WEF
1
MUTY_ECOLI
A:
[4-225]
-------
S
Q
F
S
A
Q
V
L
D
W
Y
D
K
-
Y
G
R
A
T
L
P
W
Q
I
D
K
T
P
Y
K
V
W
L
S
E
V
M
L
Q
Q
T
Q
V
A
T
V
I
P
Y
F
E
R
F
M
A
R
F
P
T
V
T
D
L
A
N
A
P
L
D
E
V
L
H
L
W
T
G
L
G
Y
Y
A
R
A
R
N
L
H
K
A
A
Q
Q
V
A
T
L
H
G
G
K
F
P
E
T
F
E
E
V
A
A
L
P
G
V
G
R
S
T
A
G
A
I
L
S
L
S
L
G
K
H
F
P
I
L
D
G
N
V
K
R
V
L
A
R
C
Y
A
V
S
G
W
P
G
K
K
E
V
E
N
K
L
W
S
L
S
E
Q
V
T
P
A
V
G
V
E
R
F
N
Q
A
M
M
D
L
G
A
M
I
C
T
R
S
K
P
K
C
S
L
C
P
L
Q
N
G
C
I
A
A
A
N
N
S
W
A
L
Y
P
G
K
K
P
K
--------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
78.08
43%
-91
- C2 -
1KG3
7
MUTY_ECOLI
A:
[4-224]
-------
S
Q
F
S
A
Q
V
L
D
W
Y
D
K
Y
G
R
K
-
T
L
P
W
Q
I
D
K
T
P
Y
K
V
W
L
S
E
V
M
L
Q
Q
T
Q
V
A
T
V
I
P
Y
F
E
R
F
M
A
R
F
P
T
V
T
D
L
A
N
A
P
L
D
E
V
L
H
L
W
T
G
L
G
Y
Y
A
R
A
R
N
L
H
K
A
A
Q
Q
V
A
T
L
H
G
G
K
F
P
E
T
F
E
E
V
A
A
L
P
G
V
G
R
S
T
A
G
A
I
L
S
L
S
L
G
K
H
F
P
I
L
D
G
N
V
K
R
V
L
A
R
C
Y
A
V
S
G
W
P
G
K
K
E
V
E
N
K
L
W
S
L
S
E
Q
V
T
P
A
V
G
V
E
R
F
N
Q
A
M
M
D
L
G
A
M
I
C
T
R
S
K
P
K
C
S
L
C
P
L
Q
N
G
C
I
A
A
A
N
N
S
W
A
L
Y
P
G
K
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
77.23
43%
-87
- C2 -
1KG2
6
MUTY_ECOLI
A:
[2-224]
-----
Q
A
S
Q
F
S
A
Q
V
L
D
W
Y
D
K
-
Y
G
R
K
T
L
P
W
Q
I
D
K
T
P
Y
K
V
W
L
S
E
V
M
L
Q
Q
T
Q
V
A
T
V
I
P
Y
F
E
R
F
M
A
R
F
P
T
V
T
D
L
A
N
A
P
L
D
E
V
L
H
L
W
T
G
L
G
Y
Y
A
R
A
R
N
L
H
K
A
A
Q
Q
V
A
T
L
H
G
G
K
F
P
E
T
F
E
E
V
A
A
L
P
G
V
G
R
S
T
A
G
A
I
L
S
L
S
L
G
K
H
F
P
I
L
D
G
N
V
K
R
V
L
A
R
C
Y
A
V
S
G
W
P
G
K
K
E
V
E
N
K
L
W
S
L
S
E
Q
V
T
P
A
V
G
V
E
R
F
N
Q
A
M
M
D
L
G
A
M
I
C
T
R
S
K
P
K
C
S
L
C
P
L
Q
N
G
C
I
A
A
A
N
N
S
W
A
L
Y
P
G
K
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
77.23
42%
-88
- C2 -
1MUD
4
MUTY_ECOLI
A:
[4-225]
-------
S
Q
F
S
A
Q
V
L
D
W
Y
D
K
Y
G
R
K
-
T
L
P
W
Q
I
D
K
T
P
Y
K
V
W
L
S
E
V
M
L
Q
Q
T
Q
V
A
T
V
I
P
Y
F
E
R
F
M
A
R
F
P
T
V
T
D
L
A
N
A
P
L
D
E
V
L
H
L
W
T
G
L
G
Y
Y
A
R
A
R
N
L
H
K
A
A
Q
Q
V
A
T
L
H
G
G
K
F
P
E
T
F
E
E
V
A
A
L
P
G
V
G
R
S
T
A
G
A
I
L
S
L
S
L
G
K
H
F
P
I
L
N
G
N
V
K
R
V
L
A
R
C
Y
A
V
S
G
W
P
G
K
K
E
V
E
N
K
L
W
S
L
S
E
Q
V
T
P
A
V
G
V
E
R
F
N
Q
A
M
M
D
L
G
A
M
I
C
T
R
S
K
P
K
C
S
L
C
P
L
Q
N
G
C
I
A
A
A
N
N
S
W
A
L
Y
P
G
K
K
P
K
--------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
77.17
43%
-88
- C2 -
1MUY
4
MUTY_ECOLI
A:
[4-225]
-------
S
Q
F
S
A
Q
V
L
D
W
Y
D
K
Y
G
R
K
-
T
L
P
W
Q
I
D
K
T
P
Y
K
V
W
L
S
E
V
M
L
Q
Q
T
Q
V
A
T
V
I
P
Y
F
E
R
F
M
A
R
F
P
T
V
T
D
L
A
N
A
P
L
D
E
V
L
H
L
W
T
G
L
G
Y
Y
A
R
A
R
N
L
H
K
A
A
Q
Q
V
A
T
L
H
G
G
K
F
P
E
T
F
E
E
V
A
A
L
P
G
V
G
R
S
T
A
G
A
I
L
S
L
S
L
G
K
H
F
P
I
L
D
G
N
V
K
R
V
L
A
R
C
Y
A
V
S
G
W
P
G
K
K
E
V
E
N
K
L
W
S
L
S
E
Q
V
T
P
A
V
G
V
E
R
F
N
Q
A
M
M
D
L
G
A
M
I
C
T
R
S
K
P
K
C
S
L
C
P
L
Q
N
G
C
I
A
A
A
N
N
S
W
A
L
Y
P
G
K
K
P
K
--------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
77.05
43%
-85
- C2 -
1KQJ
5
MUTY_ECOLI
A:
[4-225]
-------
S
Q
F
S
A
Q
V
L
D
W
Y
D
K
Y
G
R
K
-
T
L
P
W
Q
I
D
K
T
P
Y
K
V
W
L
S
E
V
M
L
Q
Q
T
Q
V
A
T
V
I
P
Y
F
E
R
F
M
A
R
F
P
T
V
T
D
L
A
N
A
P
L
D
E
V
L
H
L
W
T
G
L
G
Y
Y
A
R
A
R
N
L
H
K
A
A
Q
Q
V
A
T
L
H
G
G
K
F
P
E
T
F
E
E
V
A
A
L
P
G
V
G
R
S
T
A
G
A
I
L
S
L
S
L
G
K
H
F
P
I
L
D
G
N
V
K
R
V
L
A
R
C
Y
A
V
S
G
W
P
G
K
K
E
V
E
N
K
L
W
S
L
S
E
Q
V
T
P
A
V
G
V
E
R
F
N
Q
A
M
M
D
L
G
A
M
I
C
T
R
S
K
P
K
H
S
L
C
P
L
Q
N
G
C
I
A
A
A
N
N
S
W
A
L
Y
P
G
K
K
P
K
--------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
76.96
43%
-88
- C2 -
1KG5
6
MUTY_ECOLI
A:
[4-225]
-------
S
Q
F
S
A
Q
V
L
D
W
Y
D
K
Y
G
R
K
-
T
L
P
W
Q
I
D
K
T
P
Y
K
V
W
L
S
E
V
M
L
Q
Q
T
Q
V
A
T
V
I
P
Y
F
E
R
F
M
A
R
F
P
T
V
T
D
L
A
N
A
P
L
D
E
V
L
H
L
W
T
G
L
G
Y
Y
A
R
A
R
N
L
H
K
A
A
Q
Q
V
A
T
L
H
G
G
K
F
P
E
T
F
E
E
V
A
A
L
P
G
V
G
R
S
T
A
G
A
I
L
S
L
S
L
G
K
H
F
P
I
L
D
G
N
V
Q
R
V
L
A
R
C
Y
A
V
S
G
W
P
G
K
K
E
V
E
N
K
L
W
S
L
S
E
Q
V
T
P
A
V
G
V
E
R
F
N
Q
A
M
M
D
L
G
A
M
I
C
T
R
S
K
P
K
C
S
L
C
P
L
Q
N
G
C
I
A
A
A
N
N
S
W
A
L
Y
P
G
K
K
P
K
--------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
76.75
43%
-88
- C2 -
1KG7
5
MUTY_ECOLI
A:
[4-224]
-------
S
Q
F
S
A
Q
V
L
D
W
Y
D
K
Y
G
R
K
-
T
L
P
W
Q
I
D
K
T
P
Y
K
V
W
L
S
E
V
M
L
Q
Q
T
Q
V
A
T
V
I
P
Y
F
E
R
F
M
A
R
F
P
T
V
T
D
L
A
N
A
P
L
D
E
V
L
H
L
W
T
G
L
G
Y
Y
A
R
A
R
N
L
H
K
A
A
Q
Q
V
A
T
L
H
G
G
K
F
P
E
T
F
E
E
V
A
A
L
P
G
V
G
R
S
T
A
G
A
I
L
S
L
S
L
G
K
H
F
P
I
L
D
G
N
V
K
R
V
L
A
R
C
Y
A
V
S
G
W
P
G
K
K
E
V
A
N
K
L
W
S
L
S
E
Q
V
T
P
A
V
G
V
E
R
F
N
Q
A
M
M
D
L
G
A
M
I
C
T
R
S
K
P
K
C
S
L
C
P
L
Q
N
G
C
I
A
A
A
N
N
S
W
A
L
Y
P
G
K
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
76.63
43%
-87
- C2 -
1KG4
4
MUTY_ECOLI
A:
[4-224]
-------
S
Q
F
S
A
Q
V
L
D
W
Y
D
K
Y
G
R
K
-
T
L
P
W
Q
I
D
K
T
P
Y
K
V
W
L
S
E
V
M
L
Q
Q
T
Q
V
A
T
V
I
P
Y
F
E
R
F
M
A
R
F
P
T
V
T
D
L
A
N
A
P
L
D
E
V
L
H
L
W
T
G
L
G
Y
Y
A
R
A
R
N
L
H
K
A
A
Q
Q
V
A
T
L
H
G
G
K
F
P
E
T
F
E
E
V
A
A
L
P
G
V
G
R
S
T
A
G
A
I
L
S
L
S
L
G
K
H
F
P
I
L
D
G
N
V
A
R
V
L
A
R
C
Y
A
V
S
G
W
P
G
K
K
E
V
E
N
K
L
W
S
L
S
E
Q
V
T
P
A
V
G
V
E
R
F
N
Q
A
M
M
D
L
G
A
M
I
C
T
R
S
K
P
K
C
S
L
C
P
L
Q
N
G
C
I
A
A
A
N
N
S
W
A
L
Y
P
G
K
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
76.56
43%
-85
- C2 -
1KG6
8
MUTY_ECOLI
A:
[4-224]
-------
S
Q
F
S
A
Q
V
L
D
W
Y
D
K
Y
G
R
K
-
T
L
P
W
Q
I
D
K
T
P
Y
K
V
W
L
S
E
V
M
L
Q
Q
T
Q
V
A
T
V
I
P
Y
F
E
R
F
M
A
R
F
P
T
V
T
D
L
A
N
A
P
L
D
E
V
L
H
L
W
T
G
L
G
Y
Y
A
R
A
R
N
L
H
K
A
A
Q
Q
V
A
T
L
H
G
G
K
F
P
E
T
F
E
E
V
A
A
L
P
G
V
G
R
S
T
A
G
A
I
L
S
L
S
L
G
K
H
F
P
I
L
D
G
N
V
R
R
V
L
A
R
C
Y
A
V
S
G
W
P
G
K
K
E
V
E
N
K
L
W
S
L
S
E
Q
V
T
P
A
V
G
V
E
R
F
N
Q
A
M
M
D
L
G
A
M
I
C
T
R
S
K
P
K
C
S
L
C
P
L
Q
N
G
C
I
A
A
A
N
N
S
W
A
L
Y
P
G
K
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
75.94
43%
-86
- C2 -
1WEG
4
MUTY_ECOLI
A:
[4-225]
-------
S
Q
F
S
A
Q
V
L
D
W
Y
D
K
Y
G
R
K
-
T
L
P
W
Q
I
D
K
T
P
Y
K
V
W
L
S
E
V
M
L
Q
Q
T
Q
V
A
T
V
I
P
Y
F
E
R
F
M
A
R
F
P
T
V
T
D
L
A
N
A
P
L
D
E
V
L
H
L
W
T
G
L
G
Y
Y
A
R
A
R
N
L
H
K
A
A
Q
Q
V
A
T
L
H
G
G
K
F
P
E
T
F
E
E
V
A
A
L
P
G
V
G
R
S
T
A
G
A
I
L
S
L
S
L
G
K
H
F
P
I
L
D
G
N
V
A
R
V
L
A
R
C
Y
A
V
S
G
W
P
G
K
K
E
V
E
N
K
L
W
S
L
S
E
Q
V
T
P
A
V
G
V
E
R
F
N
Q
A
M
M
D
L
G
A
M
I
C
T
R
S
K
P
K
C
S
L
C
P
L
Q
N
G
C
I
A
A
A
N
N
S
W
A
L
Y
P
G
K
K
P
K
--------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
75.79
42%
-87
- C2 -
1MUN
7
MUTY_ECOLI
A:
[4-225]
-------
S
Q
F
S
A
Q
V
L
D
W
Y
D
K
Y
G
R
K
-
T
L
P
W
Q
I
D
K
T
P
Y
K
V
W
L
S
E
V
M
L
Q
Q
T
Q
V
A
T
V
I
P
Y
F
E
R
F
M
A
R
F
P
T
V
T
D
L
A
N
A
P
L
D
E
V
L
H
L
W
T
G
L
G
Y
Y
A
R
A
R
N
L
H
K
A
A
Q
Q
V
A
T
L
H
G
G
K
F
P
E
T
F
E
E
V
A
A
L
P
G
V
G
R
S
T
A
G
A
I
L
S
L
S
L
G
K
H
F
P
I
L
N
G
N
V
K
R
V
L
A
R
C
Y
A
V
S
G
W
P
G
K
K
E
V
E
N
K
L
W
S
L
S
E
Q
V
T
P
A
V
G
V
E
R
F
N
Q
A
M
M
D
L
G
A
M
I
C
T
R
S
K
P
K
C
S
L
C
P
L
Q
N
G
C
I
A
A
A
N
N
S
W
A
L
Y
P
G
K
K
P
K
--------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
74.71
43%
-81
- C2 -
1WEI
5
MUTY_ECOLI
A:
[4-224]
-------
S
Q
F
S
A
Q
V
L
D
W
Y
D
K
-
Y
G
R
A
T
L
P
W
Q
I
D
K
T
P
Y
K
V
W
L
S
E
V
M
L
Q
Q
T
Q
V
A
T
V
I
P
Y
F
E
R
F
M
A
R
F
P
T
V
T
D
L
A
N
A
P
L
D
E
V
L
H
L
W
T
G
L
G
Y
Y
A
R
A
R
N
L
H
K
A
A
Q
Q
V
A
T
L
H
G
G
K
F
P
E
T
F
E
E
V
A
A
L
P
G
V
G
R
S
T
A
G
A
I
L
S
L
S
L
G
K
H
F
P
I
L
D
G
N
V
K
R
V
L
A
R
-
Y
A
V
S
G
W
P
G
K
K
E
V
E
N
K
L
W
-
L
S
E
Q
V
T
P
A
V
G
V
E
R
F
N
Q
A
M
M
D
L
G
A
M
-
C
T
R
S
K
P
K
C
-
L
C
P
L
Q
N
G
C
I
A
A
A
N
N
S
W
A
L
Y
P
G
K
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------