@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1783: (2015-12-10 )
MSSYWNNYPELKKNIDETNQLIQERIQVRNKDIEAALSQLTAAGGKQLRPAFFYLFSQLGNKENQDTQQLKKIAASLEILHVATLIHDDVIDDSPLRRGNMTIQSKFGKDIAVYTGDLLFTVFFDLILESMADTPFMRINAKSMRKILMGELDQMHLRYNQQQGIHHYLRAISGKTAELFKLASKEGAYFGGAEKEVVRLAGHIGFNIGMTFQILDDILDYTADKKTFNKPVLEDLTQGVYSLPLLLAIEENPDIFKPILDKKTDMATEDMEKIAYLVVSHRGVDKARHLARKFTEKAISDINKLPQNSAKKQLLQLTNYLLKRKI
Atome Classification :
(20 SA)
.........10-........20.....--...30.---......----.40---...--......50.......----.60....---....70----..--......80........90........100.......110.......120.......130...------....140.......150.......160.......170.......180.......190---..--.....200........210.......220.......230.......240.......-----250----..-----.....260-----......----.-----.270........--.280.......290.......300.......------310.......320....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MS
S
Y
W
NN
Y
P
E
L
-
K
K
N
I
D
E
T
N
Q
L
I
Q
E
R
I
--
Q
VRN
K
D
---
I
E
A
A
L
S
----
Q
L
----
T
AA--GGKQ
L
R
P
A
F
F
Y
L
F
S
Q
----LGNKENQ---
D
T
Q
Q
L
K
----
K
I
--
A
A
S
L
E
I
L
H
V
A
T
L
I
HDDVIDDSPLRRG
N
M
T
I
Q
SKFGK
D
I
A
V
YT
G
D
L
L
F
T
V
F
F
D
L
I
L
E
S
MADT
P
------
F
M
R
I
N
A
K
S
M
R
K
I
L
M
G
E
L
D
Q
M
H
L
R
YNQ
Q
Q
G
I
H
H
Y
L
R
A
ISG
K
T
A
E
L
F
K
L
ASKEGAYFGG---
A
E
--
K
E
V
V
R
L
-
A
G
HIGFNI
G
M
T
F
Q
I
L
D
D
I
L
D
YTADKKTFN
K
P
V
L
E
D
L
T
Q
G
V
Y
SL
P
L
L
L
A
I-----EEN----P
D
-----
I
F
K
P
I
LD------KKTDM
A
----
T
-----
E
D
--
M
E
K
I
A
Y
L
V
--
V
SHRG
V
D
K
A
R
H
L
A
R
K
F
T
E
K
A
I
S
D
I
N
KLPQ
N
S
------
A
K
K
Q
L
L
Q
L
T
N
Y
L
L
KRKI
1
PsiBlast_PDB
97.24
45%
-88
- C1 -
3PKO
2
?
A:
[15-332]
----
W
R
Q
F
P
Q
V
-
E
P
Q
L
T
A
L
Q
D
Y
L
L
R
T
V
--
Q
L
D
N
Q
P
---
I
H
H
K
I
L
----
A
L
----
L
K
S
--
G
G
K
L
L
R
P
G
Y
F
Y
L
F
S
T
----
F
G
N
A
A
T
-----
P
A
Q
L
Q
----
A
G
--
A
A
A
I
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I
L
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D
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V
R
T
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M
T
Y
G
Q
R
N
A
I
Y
A
G
D
F
M
F
T
V
Y
F
D
Q
V
L
K
S
T
T
D
R
S
------
L
I
Q
N
H
I
D
A
M
H
R
I
L
Q
G
E
L
H
Q
M
D
L
N
Y
R
E
D
I
T
L
D
A
Y
L
N
E
I
A
G
K
T
A
E
L
F
A
L
S
C
Y
Q
G
A
Q
L
A
G
---
A
P
--
Q
S
V
I
D
R
-
T
R
D
I
G
I
A
I
G
C
A
Y
Q
M
L
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D
I
L
D
Y
A
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D
P
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Q
K
P
V
L
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D
L
R
S
G
V
Y
S
L
P
L
L
L
S
L
-----
S
H
A
----
P
R
-----
D
F
H
K
L
L
K
------
K
K
Q
A
M
T
----
L
-----
E
D
--
I
K
H
V
Q
A
L
V
--
A
Q
Y
D
G
V
G
A
A
K
Q
L
A
Q
D
Y
T
D
R
A
L
T
L
I
Q
Q
L
P
V
G
S
------
A
Q
Q
S
L
E
Q
L
T
R
L
L
L
R
R
D
-
2
PsiBlast_PDB
96.71
45%
-88
- C1 -
3N3D
4
?
A:
[8-325]
----
W
R
Q
F
P
Q
V
-
E
P
Q
L
T
A
L
Q
D
Y
L
L
R
T
V
--
Q
L
D
N
Q
P
---
I
H
H
K
I
L
----
A
L
----
L
K
S
--
G
G
K
L
L
R
P
G
Y
F
Y
L
F
S
T
----
F
G
N
A
A
T
-----
P
A
Q
L
Q
----
A
G
--
A
A
A
I
E
I
L
H
V
G
T
L
I
H
D
D
V
I
D
D
S
P
T
R
R
G
V
R
T
I
Q
M
T
Y
G
Q
R
N
A
I
Y
A
G
D
F
M
F
T
V
Y
F
D
Q
V
L
K
S
T
T
D
R
S
------
L
I
Q
N
H
I
D
A
M
H
R
I
L
Q
G
E
L
H
Q
M
D
L
N
Y
R
E
D
I
T
L
D
A
Y
L
N
E
I
A
G
K
T
A
E
L
F
A
L
S
C
Y
Q
G
A
Q
L
A
G
---
A
P
--
Q
S
V
I
D
R
-
T
R
D
I
G
I
A
I
G
C
A
Y
Q
M
L
D
D
I
L
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Y
A
G
D
P
K
R
T
Q
K
P
V
L
E
D
L
R
S
G
V
Y
S
L
P
L
L
L
S
L
-----
S
H
A
----
P
R
-----
D
F
H
K
L
L
K
------
K
K
Q
A
M
T
----
L
-----
E
D
--
I
K
H
V
Q
A
L
V
--
A
Q
Y
D
G
V
G
A
A
K
Q
L
A
Q
D
Y
T
D
R
A
L
T
L
I
Q
Q
L
P
V
G
S
------
A
Q
Q
S
L
E
Q
L
T
R
L
L
L
R
R
--
21
PsiBlast_CBE
96.21
45%
-93
- C1 -
3PKO
1
?
B:
[15-332]
----
W
R
Q
F
P
Q
V
-
E
P
Q
L
T
A
L
Q
D
Y
L
L
R
T
V
--
Q
L
D
N
Q
P
---
I
H
H
K
I
L
----
A
L
----
L
K
S
--
G
G
K
L
L
R
P
G
Y
F
Y
L
F
S
T
----
F
G
N
A
A
T
-----
P
A
Q
L
Q
----
A
G
--
A
A
A
I
E
I
L
H
V
G
T
L
I
H
D
D
V
I
--------------
T
Y
G
Q
R
N
A
I
Y
A
G
D
F
M
F
T
V
Y
F
D
Q
V
L
K
S
T
T
D
R
S
------
L
I
Q
N
H
I
D
A
M
H
R
I
L
Q
G
E
L
H
Q
M
D
L
N
Y
R
E
D
I
T
L
D
A
Y
L
N
E
I
A
G
K
T
A
E
L
F
A
L
S
C
Y
Q
G
A
Q
L
A
G
---
A
P
--
Q
S
V
I
D
R
-
T
R
D
I
G
I
A
I
G
C
A
Y
Q
M
L
D
D
I
L
D
Y
A
G
D
P
K
R
T
Q
K
P
V
L
E
D
L
R
S
G
V
Y
S
L
P
L
L
L
S
L
-----
S
H
A
----
P
R
-----
D
F
H
K
L
L
K
------
K
K
Q
A
M
T
----
L
-----
E
D
--
I
K
H
V
Q
A
L
V
--
A
Q
Y
D
G
V
G
A
A
K
Q
L
A
Q
D
Y
T
D
R
A
L
T
L
I
Q
Q
L
P
V
G
S
------
A
Q
Q
S
L
E
Q
L
T
R
L
L
L
R
R
D
-
22
PsiBlast_CBE
95.55
45%
-93
- C1 -
3N3D
1
?
B:
[8-325]
----
W
R
Q
F
P
Q
V
-
E
P
Q
L
T
A
L
Q
D
Y
L
L
R
T
V
--
Q
L
D
N
Q
P
---
I
H
H
K
I
L
----
A
L
----
L
K
S
--
G
G
K
L
L
R
P
G
Y
F
Y
L
F
S
T
----
F
G
N
A
A
T
-----
P
A
Q
L
Q
----
A
G
--
A
A
A
I
E
I
L
H
V
G
T
L
I
H
D
D
V
I
D
D
----------
Q
M
T
Y
G
Q
R
N
A
I
Y
A
G
D
F
M
F
T
V
Y
F
D
Q
V
L
K
S
T
T
D
R
S
------
L
I
Q
N
H
I
D
A
M
H
R
I
L
Q
G
E
L
H
Q
M
D
L
N
Y
R
E
D
I
T
L
D
A
Y
L
N
E
I
A
G
K
T
A
E
L
F
A
L
S
C
Y
Q
G
A
Q
L
A
G
---
A
P
--
Q
S
V
I
D
R
-
T
R
D
I
G
I
A
I
G
C
A
Y
Q
M
L
D
D
I
L
D
Y
A
G
D
P
K
R
T
Q
K
P
V
L
E
D
L
R
S
G
V
Y
S
L
P
L
L
L
S
L
-----
S
H
A
----
P
R
-----
D
F
H
K
L
L
K
------
K
K
Q
A
M
T
----
L
-----
E
D
--
I
K
H
V
Q
A
L
V
--
A
Q
Y
D
G
V
G
A
A
K
Q
L
A
Q
D
Y
T
D
R
A
L
T
L
I
Q
Q
L
P
V
G
S
------
A
Q
Q
S
L
E
Q
L
T
R
L
L
L
R
R
--
46
HHSearch
94.05
44%
-84
- C1 -
3PKO
2
?
A:
[14-333]
---
L
W
R
Q
F
P
Q
V
-
E
P
Q
L
T
A
L
Q
D
Y
L
L
R
T
V
--
Q
L
D
N
Q
P
---
I
H
H
K
I
L
----
A
L
----
L
K
S
--
G
G
K
L
L
R
P
G
Y
F
Y
L
F
S
T
----
F
G
N
A
A
T
-----
P
A
Q
L
Q
----
A
G
--
A
A
A
I
E
I
L
H
V
G
T
L
I
H
D
D
V
I
D
D
S
P
T
R
R
G
V
R
T
I
Q
M
T
Y
G
Q
R
N
A
I
Y
A
G
D
F
M
F
T
V
Y
F
D
Q
V
L
K
S
T
T
D
R
S
------
L
I
Q
N
H
I
D
A
M
H
R
I
L
Q
G
E
L
H
Q
M
D
L
N
Y
R
E
D
I
T
L
D
A
Y
L
N
E
I
A
G
K
T
A
E
L
F
A
L
S
C
Y
Q
G
A
Q
L
A
G
---
A
P
--
Q
S
V
I
D
R
-
T
R
D
I
G
I
A
I
G
C
A
Y
Q
M
L
D
D
I
L
D
Y
A
G
D
P
K
R
T
Q
K
P
V
L
E
D
L
R
S
G
V
Y
S
L
P
L
L
L
S
L
-----
S
H
A
----
P
R
-----
D
----
F
H
------
K
L
L
K
K
K
QAMT
L
-----
E
D
--
I
K
H
V
Q
A
L
V
--
A
Q
Y
D
G
V
G
A
A
K
Q
L
A
Q
D
Y
T
D
R
A
L
T
L
I
Q
Q
L
P
V
G
S
------
A
Q
Q
S
L
E
Q
L
T
R
L
L
L
R
R
D
-
3
PsiBlast_PDB
79.27
34%
-80
- C1 -
3AQB
3
HEXB_MICLU
B:
[10-323]
----------
L
-
N
P
Y
I
I
E
V
E
K
R
L
Y
E
C
I
--
Q
S
D
S
E
T
---
I
N
K
A
A
H
----
H
I
----
L
S
S
--
G
G
K
R
V
R
P
M
F
V
L
L
S
G
F
----
L
N
D
T
Q
K
D
---
D
---
L
I
----
R
T
--
A
V
S
L
E
L
V
H
M
A
S
L
V
H
D
D
Y
I
D
N
S
D
M
R
R
G
N
T
S
V
H
I
A
F
D
K
D
T
A
I
R
T
G
H
F
L
L
A
R
A
L
Q
N
I
-
A
T
I
N
N
S
K
------
F
H
Q
I
F
S
K
T
I
L
E
V
C
F
G
E
F
D
Q
M
A
D
R
F
N
Y
P
V
S
F
T
A
Y
L
R
R
I
N
R
K
T
A
I
L
I
E
A
S
C
H
L
G
A
L
S
S
Q
---
L
D
--
E
Q
S
T
Y
H
-
I
K
Q
F
G
H
C
I
G
M
S
Y
Q
I
I
D
D
I
L
D
Y
T
S
D
E
A
T
L
G
K
P
V
G
S
D
I
R
N
G
H
I
T
Y
P
L
M
A
A
I
A
N
L
K
-
E
Q
D
----
D
D
-----
K
L
E
A
V
V
K
------
H
L
T
--
S
----
T
-----
S
D
--
D
E
V
Y
Q
Y
I
V
S
Q
V
K
Q
Y
G
I
E
P
A
E
L
L
S
R
K
Y
G
D
K
A
K
Y
H
L
S
Q
L
Q
D
S
N
------
I
K
D
Y
L
E
E
I
H
E
K
M
L
K
R
V
Y
25
PsiBlast_CBE
79.08
32%
-72
- C1 -
3OYR
4
?
B:
[38-344]
------------------
V
N
R
L
I
T
D
R
M
--
Q
S
D
V
A
I
---
I
P
A
L
A
E
----
H
L
----
I
A
A
--
G
G
K
R
L
R
P
L
M
T
V
A
A
A
R
----
L
A
G
A
D
N
D
------
H
F
Q
----
K
L
--
A
A
A
V
E
F
I
H
T
A
T
L
L
H
D
D
V
V
D
G
S
Q
L
R
R
G
K
V
A
A
H
L
I
W
G
G
A
Q
S
V
L
V
G
D
F
L
F
A
R
A
F
E
L
M
V
E
T
N
S
-
M
K
------
A
L
E
I
L
A
R
A
S
R
V
I
A
E
G
E
V
L
Q
L
M
R
S
H
D
L
N
L
S
Q
A
V
Y
L
E
I
I
Q
A
K
T
A
E
L
F
A
A
A
S
E
A
G
A
V
S
A
G
VD
V
A
K
--
S
E
A
L
R
----
D
Y
G
L
N
L
G
L
A
F
Q
L
A
D
D
A
L
D
Y
G
G
A
T
E
T
L
G
K
N
A
G
D
D
F
R
E
G
K
A
T
L
P
L
L
L
A
I
-----
A
R
S
GPRE
A
E
-----
F
W
E
R
A
I
G
------
R
R
-
E
Q
T
----
E
-----
A
D
--
F
R
R
A
R
E
L
I
--
I
G
S
G
A
L
D
A
T
L
D
L
A
A
D
Y
A
D
K
A
K
A
A
L
A
M
F
P
A
N
D
------
W
R
E
A
L
E
E
L
A
D
F
A
V
S
R
R
A
4
PsiBlast_PDB
78.87
34%
-81
- C1 -
3AQC
5
HEXB_MICLU
B:
[10-323]
----------
L
-
N
P
Y
I
I
E
V
E
K
R
L
Y
E
C
I
--
Q
S
D
S
E
T
---
I
N
K
A
A
H
----
H
I
----
L
S
S
--
G
G
K
R
V
R
P
M
F
V
L
L
S
G
F
----
L
N
D
T
Q
K
D
---
D
---
L
I
----
R
T
--
A
V
S
L
E
L
V
H
M
A
S
L
V
H
D
D
Y
I
D
N
S
D
M
R
R
G
N
T
S
V
H
I
A
F
D
K
D
T
A
I
R
T
G
H
F
L
L
A
R
A
L
Q
N
I
-
A
T
I
N
N
S
K
------
F
H
Q
I
F
S
K
T
I
L
E
V
C
F
G
E
F
D
Q
M
A
D
R
F
N
Y
P
V
S
F
T
A
Y
L
R
R
I
N
R
K
T
A
I
L
I
E
A
S
C
H
L
G
A
L
S
S
Q
---
L
D
--
E
Q
S
T
Y
H
-
I
K
Q
F
G
H
C
I
G
M
S
Y
Q
I
I
D
D
I
L
D
Y
T
S
D
E
A
T
L
G
K
P
V
G
S
D
I
R
N
G
H
I
T
Y
P
L
M
A
A
I
A
N
L
K
-
E
Q
D
----
D
D
-----
K
L
E
A
V
V
K
------
H
L
T
--
S
----
T
-----
S
D
--
D
E
V
Y
Q
Y
I
V
S
Q
V
K
Q
Y
G
I
E
P
A
E
L
L
S
R
K
Y
G
D
K
A
K
Y
H
L
S
Q
L
Q
D
S
N
------
I
K
D
Y
L
E
E
I
H
E
K
M
L
K
R
V
Y
23
PsiBlast_CBE
78.40
34%
-86
- C1 -
3AQC
5
HEXB_MICLU
D:
[10-323]
----------
L
-
N
P
Y
I
I
E
V
E
K
R
L
Y
E
C
I
--
Q
S
D
S
E
T
---
I
N
K
A
A
H
----
H
I
----
L
S
S
--
G
G
K
R
V
R
P
M
F
V
L
L
S
G
F
----
L
N
D
T
Q
K
D
---
D
---
L
I
----
R
T
--
A
V
S
L
E
L
V
H
M
A
S
L
V
H
D
D
Y
I
D
N
S
D
M
R
R
G
N
T
S
V
H
I
A
F
D
K
D
T
A
I
R
T
G
H
F
L
L
A
R
A
L
Q
N
I
-
A
T
I
N
N
S
K
------
F
H
Q
I
F
S
K
T
I
L
E
V
C
F
G
E
F
D
Q
M
A
D
R
F
N
Y
P
V
S
F
T
A
Y
L
R
R
I
N
R
K
T
A
I
L
I
E
A
S
C
H
L
G
A
L
S
S
Q
---
L
D
--
E
Q
S
T
Y
H
-
I
K
Q
F
G
H
C
I
G
M
S
Y
Q
I
I
D
D
I
L
D
Y
T
S
D
E
A
T
L
G
K
P
V
G
S
D
I
R
N
G
H
I
T
Y
P
L
M
A
A
I
ANLK-
E
Q
D
----
D
D
-----
K
L
E
A
V
V
K
------
H
L
T
--
S
----
T
-----
S
D
--
D
E
V
Y
Q
Y
I
V
SQ
V
K
Q
Y
G
I
E
P
A
E
L
L
S
R
K
Y
G
D
K
A
K
Y
H
L
S
Q
L
Q
D
S
N
------
I
K
D
Y
L
E
E
I
H
E
K
M
L
K
R
V
Y
39
HHSearch
78.34
31%
-77
- C1 -
3OYR
1
?
A:
[23-343]
--
S
V
D
R
L
V
R
L
A
-
E
A
D
M
A
G
V
N
R
L
I
T
D
R
M
--
Q
S
D
V
A
I
---
I
P
A
L
A
E
----
H
L
----
I
A
A
--
G
G
K
R
L
R
P
L
M
T
V
A
A
A
R
----
L
A
G
A
D
------
N
D
H
F
Q
----
K
L
--
A
A
A
V
E
F
I
H
T
A
T
L
L
H
D
D
V
V
---------
V
A
A
H
L
I
W
G
G
A
Q
S
V
L
V
G
D
F
L
F
A
R
A
F
E
L
M
V
E
-
T
N
S
M
K
------
A
L
E
I
L
A
R
A
S
R
V
I
A
E
G
E
V
L
Q
L
M
R
S
H
D
L
N
L
S
Q
A
V
Y
L
E
I
I
Q
A
K
T
A
E
L
F
A
A
A
S
E
A
G
A
V
S
A
G
---
V
D
--
V
A
K
S
E
A
-
L
R
D
Y
G
L
N
L
G
L
A
F
Q
L
A
D
D
A
L
D
Y
-------------------
A
T
L
P
L
L
L
A
I
-----
A
R
S
----
G
P
-----
R
E
A
E
F
W
E
------
R
A
I
G
--T---
E
-----
A
D
--
F
R
R
A
R
E
L
I
--
I
G
S
G
A
L
D
A
T
L
D
L
A
A
D
Y
A
D
K
A
K
A
A
L
A
M
F
P
A
N
D
------
W
R
E
A
L
E
E
L
A
D
F
A
V
S
R
--
5
PsiBlast_PDB
78.28
32%
-82
- C1 -
4LOB
4
?
A:
[43-345]
-------------------
D
H
L
I
N
E
G
I
--
S
S
K
V
G
L
---
V
M
S
V
S
K
----
H
V
----
V
E
A
--
G
G
K
R
M
R
P
I
M
C
L
L
A
A
R
----
A
C
D
L
D
N
M
-----
Q
N
A
Q
----
R
L
--
A
A
I
I
E
M
L
H
T
A
T
L
V
H
D
D
V
V
D
--------------
W
N
N
Q
T
A
V
L
V
G
D
F
L
I
A
R
A
F
D
L
L
V
D
-
L
N
N
M
T
------
L
L
K
D
F
S
T
G
T
C
E
I
A
E
G
E
V
L
Q
L
Q
S
Q
H
Q
P
D
T
T
E
E
T
Y
L
K
I
I
H
G
K
T
S
R
L
F
E
L
A
T
E
G
A
A
I
L
A
G
---
Q
E
AY
R
E
P
L
R
L
F
A
G
H
----
F
G
N
A
F
Q
I
I
D
D
I
L
D
Y
T
S
D
A
E
T
L
G
K
N
I
G
D
D
L
M
E
G
K
P
T
L
P
L
I
S
A
L
A
H
S
TG
E
E
H
----
A
I
-----
I
R
R
S
I
A
T
------
G
G
V
D
-------------
Q
--
L
P
K
V
I
E
I
V
--
Q
K
S
G
A
L
D
Y
C
Q
R
R
A
Q
E
E
T
E
A
A
L
Q
A
L
S
I
L
P
D
T
P
------
Y
R
Q
A
L
I
N
L
T
R
L
A
L
H
R
I
-
70
Fugue
77.75
31%
-76
- C1 -
3OYR
1
?
A:
[20-343]
K
S
G
S
V
D
R
L
V
R
L
A
E
A
D
M
A
G
V
N
R
L
I
T
D
R
M
--
Q
S
D
V
A
I
---
I
P
A
L
A
E
----
H
L
----
I
A
A
--
G
G
K
R
L
R
P
L
M
T
V
A
A
A
R
----
L
A
G
A
D
N
D
---
H
---
F
Q
----
K
L
--
A
A
A
V
E
F
I
H
T
A
T
L
L
H
D
D
V
V
V
A
A
---------
H
L
I
W
G
G
A
Q
S
V
L
V
G
D
F
L
F
A
R
A
F
E
L
M
V
E
-
T
N
S
M
K
------
A
L
E
I
L
A
R
A
S
R
V
I
A
E
G
E
V
L
Q
L
M
R
S
H
D
L
N
L
S
Q
A
V
Y
L
E
I
I
Q
A
K
T
A
E
L
F
A
A
A
S
E
A
G
A
V
S
A
G
---
V
D
--
V
A
K
S
E
A
-
L
R
D
Y
G
L
N
L
G
L
A
F
Q
L
A
D
D
A
L
D
Y
A
-------------------
T
L
P
L
L
L
A
I
-----
A
R
S
----
G
P
-----
R
E
A
E
F
W
E
------
R
A
I
G
-
T
----
E
-----
A
D
--
F
R
R
A
R
E
L
I
--
I
G
S
G
A
L
D
A
T
L
D
L
A
A
D
Y
A
D
K
A
K
A
A
L
A
M
F
P
A
N
D
------
W
R
E
A
L
E
E
L
A
D
F
A
V
S
R
--
24
PsiBlast_CBE
77.75
34%
-83
- C1 -
3AQB
3
HEXB_MICLU
D:
[10-323]
----------
L
-
N
P
Y
I
I
E
V
E
K
R
L
Y
E
C
I
--
Q
S
D
S
E
T
---
I
N
K
A
A
H
----
H
I
----
L
S
S
--
G
G
K
R
V
R
P
M
F
V
L
L
S
G
F
----
L
N
D
T
Q
K
D
---
D
---
L
I
----
R
T
--
A
V
S
L
E
L
V
H
M
A
S
L
V
H
D
D
Y
I
D
N
S
D
M
R
R
G
N
T
S
V
H
I
A
F
D
K
D
T
A
I
R
T
G
H
F
L
L
A
R
A
L
Q
N
I
-
A
T
I
N
N
S
K
------
F
H
Q
I
F
S
K
T
I
L
E
V
C
F
G
E
F
D
Q
M
A
D
R
F
N
Y
P
V
S
F
T
A
Y
L
R
R
I
N
R
K
T
A
I
L
I
E
A
S
C
H
L
G
A
L
S
S
Q
---
L
D
--
E
Q
S
T
Y
H
-
I
K
Q
F
G
H
C
I
G
M
S
Y
Q
I
I
D
D
I
L
D
Y
T
S
D
E
A
T
L
G
K
P
V
G
S
D
I
R
N
G
H
I
T
Y
P
L
M
A
A
I
ANLK-
E
Q
D
----
D
D
-----
K
L
E
A
V
V
K
------
H
L
T
--
S
----
T
-----
S
D
--
D
E
V
Y
Q
Y
I
V
SQ
V
K
Q
Y
G
I
E
P
A
E
L
L
S
R
K
Y
G
D
K
A
K
Y
H
L
S
Q
L
Q
D
S
N
------
I
K
D
Y
L
E
E
I
H
E
K
M
L
K
R
V
Y
65
Fugue
77.03
31%
-70
- C1 -
3AQB
3
HEXB_MICLU
B:
[5-325]
-----
S
Y
K
A
F
L
-
N
P
Y
I
I
E
V
E
K
R
L
Y
E
C
I
--
Q
S
D
S
E
T
---
I
N
K
A
A
H
----
H
I
----
L
S
S
--
G
G
K
R
V
R
P
M
F
V
L
L
S
G
F
----
L
N
D
T
Q
K
------
D
D
L
I
----
R
T
--
A
V
S
L
E
L
V
H
M
A
S
L
V
H
D
D
Y
I
D
N
S
D
M
R
R
G
N
T
S
V
H
I
A
F
D
K
D
T
A
I
R
T
G
H
F
L
L
A
R
A
L
Q
N
-
I
A
T
I
N
N
S
K
------
F
H
Q
I
F
S
K
T
I
L
E
V
C
F
G
E
F
D
Q
M
A
D
R
F
N
Y
P
V
S
F
T
A
Y
L
R
R
I
N
R
K
T
A
I
L
I
E
A
S
C
H
L
G
A
L
S
S
Q
---
L
D
--
E
Q
S
T
Y
H
-
I
K
Q
F
G
H
C
I
G
M
S
Y
Q
I
I
D
D
I
L
D
Y
T
S
D
E
A
T
L
G
K
P
V
G
S
D
I
R
N
G
H
I
T
Y
P
L
M
A
A
I
-----
A
N
L
----
K
E
Q
DDD-
K
L
E
A
V
V
K
------
H
L
T
S
T
S
----
D
-----
D
E
--
V
Y
Q
Y
I
V
S
Q
--
V
K
Q
Y
G
I
E
P
A
E
L
L
S
R
K
Y
G
D
K
A
K
Y
H
L
S
Q
L
Q
D
S
N
------
I
K
D
Y
L
E
E
I
H
E
K
M
L
K
R
V
Y
6
PsiBlast_PDB
76.23
32%
-87
- C1 -
3OYR
1
?
A:
[38-343]
------------------
V
N
R
L
I
T
D
R
M
--
Q
S
D
V
A
I
---
I
P
A
L
A
E
----
H
L
----
I
A
A
--
G
G
K
R
L
R
P
L
M
T
V
A
A
A
R
----
L
A
G
A
D
N
D
------
H
F
Q
----
K
L
--
A
A
A
V
E
F
I
H
T
A
T
L
L
H
D
D
V
V
---------
V
A
A
H
L
I
W
G
G
A
Q
S
V
L
V
G
D
F
L
F
A
R
A
F
E
L
M
V
E
T
N
S
-
M
K
------
A
L
E
I
L
A
R
A
S
R
V
I
A
E
G
E
V
L
Q
L
M
R
S
H
D
L
N
L
S
Q
A
V
Y
L
E
I
I
Q
A
K
T
A
E
L
F
A
A
A
S
E
A
G
A
V
S
A
G
VD
V
A
K
--
S
E
A
L
R
----
D
Y
G
L
N
L
G
L
A
F
Q
L
A
D
D
A
L
D
Y
-------------------
A
T
L
P
L
L
L
A
I
-----
A
R
S
GPRE
A
E
-----
F
W
E
R
A
I
G
-----------
T
----
E
-----
A
D
--
F
R
R
A
R
E
L
I
--
I
G
S
G
A
L
D
A
T
L
D
L
A
A
D
Y
A
D
K
A
K
A
A
L
A
M
F
P
A
N
D
------
W
R
E
A
L
E
E
L
A
D
F
A
V
S
R
--
8
PsiBlast_PDB
74.56
28%
-73
- C1 -
3Q2Q
5
?
A:
[34-350]
--------
P
E
L
-
T
A
R
I
N
D
A
M
V
Q
V
E
E
L
L
--
H
T
E
L
S
S
---
G
E
D
F
L
V
D
I
V
M
H
L
----
T
R
A
--
G
G
K
R
F
R
P
M
F
A
L
L
A
S
E
----
F
G
E
K
P
L
-----
S
E
N
V
I
----
K
A
--
A
V
V
V
E
I
T
H
L
A
T
L
Y
H
D
D
V
M
D
E
A
-------
S
A
N
A
R
W
D
N
S
V
A
I
L
A
G
D
I
L
L
A
H
A
S
G
L
M
S
Q
L
G
T
D
T
--------
V
A
H
F
A
E
T
F
G
E
L
V
T
G
Q
M
R
E
T
-
V
G
P
R
D
T
D
P
I
E
H
Y
T
N
V
I
R
E
K
T
G
V
L
I
A
S
A
G
Y
L
G
A
M
H
A
G
---
A
A
--
P
E
H
I
D
A
-
L
K
N
F
G
A
A
V
G
M
I
F
Q
I
V
D
D
I
I
D
I
F
S
E
T
H
----
T
P
G
T
D
L
R
E
G
V
F
T
L
P
V
L
Y
A
L
-----
R
E
D
----
T
P
-----
V
G
A
E
L
R
D
------
I
L
T
G
P
L
----
E
-----
D
D
E
T
V
N
H
V
L
E
L
L
--
S
Q
S
G
G
R
Q
A
A
L
D
E
V
Y
R
Y
M
D
I
A
N
A
E
L
D
R
L
P
D
S
T
------
V
K
E
A
L
R
N
L
A
T
F
T
V
K
R
V
G
9
PsiBlast_PDB
73.15
28%
-87
- C1 -
3APZ
-
SPS3_ARATH
A:
[50-346]
------------------------------------------------------------
G
K
Q
F
R
S
T
I
L
L
L
M
A
T
A
L
DV-----------
T
S
E
L
R
V
R
Q
R
G
I
--
A
E
I
T
E
M
I
H
V
A
S
L
L
H
D
D
----------------
V
M
G
N
K
M
S
V
L
A
G
D
F
L
L
S
R
A
C
G
-
A
L
A
A
L
K
N
T
E
------
V
V
A
L
L
A
T
A
V
E
H
L
V
T
G
E
T
M
E
I
T
S
S
T
E
Q
R
Y
S
M
D
Y
Y
M
Q
K
T
Y
Y
K
T
A
S
L
I
S
N
S
C
K
A
V
A
V
L
T
G
---
Q
T
--
A
E
V
A
V
L
-
A
F
E
Y
G
R
N
L
G
L
A
F
Q
L
I
D
D
I
L
D
F
T
G
T
S
A
S
L
G
K
G
S
L
S
D
I
R
H
G
V
I
T
A
P
I
L
F
A
M
-----
E
E
F
----
P
Q
-----
L
-
R
E
V
V
D
Q
V
EKD
P
R
N
V
D
I
A
----
L
-----
E
Y
--
L
G
K
---------
S
K
G
I
Q
R
A
R
E
L
A
M
E
H
A
N
L
A
A
A
A
I
G
S
L
P
E
T
D
N
E
D
V
K
R
S
R
R
A
L
I
D
L
T
H
R
V
I
T
R
N
K
11
PsiBlast_PDB
72.36
28%
-89
- C1 -
4JYX
4
?
A:
[40-343]
-------------------
N
Q
L
I
Q
K
Q
V
-----
N
S
D
---
V
-
S
L
I
N
----
Q
L
G
F
Y
I
V
N
S
--
G
G
K
R
L
R
P
L
L
T
V
L
A
A
R
----
A
L
N
I
Q
------
T
E
Q
H
H
----
T
L
--
A
A
I
I
E
F
I
H
T
A
T
L
L
H
D
D
V
V
D
E
S
T
M
R
R
G
R
E
T
A
N
E
V
F
G
N
Q
A
S
V
L
V
G
D
F
L
Y
T
R
S
F
Q
M
M
V
-
T
L
D
S
M
R
------
V
M
Q
I
L
S
D
A
T
N
V
I
A
E
G
E
V
L
Q
L
M
N
C
N
D
P
D
T
T
E
E
S
Y
M
E
V
I
Y
S
K
T
A
R
L
F
E
A
A
T
L
L
A
G
V
L
T
K
---
Q
S
--
E
A
I
E
N
A
-
M
Q
D
Y
G
K
Y
L
G
T
A
F
Q
L
V
D
D
I
M
D
Y
A
S
-------
N
M
G
D
D
L
A
E
G
K
P
T
L
P
L
L
Y
A
M
W
H
GN-
E
Q
Q
----
T
A
-----
I
I
R
E
A
I
E
------
T
G
N
G
M
D
----
N
L
T
P
I
L
E
T
--
M
E
Q
T
G
A
L
T
--
Y
T
-------
K
Q
Q
A
L
K
A
S
Q
Q
A
I
D
A
L
S
P
I
E
E
S
V
------
Y
K
E
A
L
I
G
L
A
H
I
S
V
E
R
V
A
7
PsiBlast_PDB
70.70
28%
-62
- C1 -
1WY0
2
?
A:
[2-341]
-----
E
K
Y
E
E
L
-
F
A
R
I
K
E
K
A
K
L
I
D
E
K
I
F
E
L
I
P
E
K
D
P
R
V
L
Y
E
A
A
R
----
H
Y
----
P
L
A
--
G
G
K
R
V
R
P
-----
F
V
V
----
L
T
S
T
E
A
V
---
G
G
D
P
L
R
----
A
I
Y
P
A
V
A
I
E
L
I
H
N
Y
S
L
V
H
D
D
I
M
D
M
D
E
T
R
R
G
K
P
T
V
H
R
I
W
G
V
N
M
A
I
L
A
G
D
L
L
F
S
K
A
F
E
A
V
--
A
R
A
E
I
P
P
E
K
K
A
R
V
L
E
V
I
V
K
A
S
N
E
L
C
E
G
Q
A
R
D
L
E
F
E
K
K
S
T
V
T
I
E
E
Y
M
E
M
I
S
G
K
T
G
A
L
F
E
A
S
A
K
V
G
G
I
I
G
T
---
D
N
--
E
E
Y
I
K
A
-
L
S
S
W
G
R
N
V
G
I
A
F
Q
I
W
D
D
V
L
D
L
I
A
D
E
K
K
L
G
K
P
V
G
S
D
I
R
K
G
K
K
T
L
-
I
V
A
H
F
-----
F
E
N
----
A
D
E
K
D
K
Q
R
F
L
K
I
F
G
------
K
--
D
I
K
----
S
-----
D
V
--
M
E
A
I
D
-
L
L
--
K
K
Y
G
S
I
D
Y
A
A
E
I
A
K
D
M
I
K
K
A
N
E
A
L
R
I
L
P
K
S
K
------
A
R
M
D
L
E
L
L
A
K
F
I
V
E
R
E
-
44
HHSearch
70.52
26%
-72
- C1 -
3APZ
-
SPS3_ARATH
A:
[8-348]
----
L
D
P
F
S
L
V
-
A
D
E
L
S
L
L
S
N
K
L
R
E
M
V
--
L
A
E
V
P
-----------------------GV
Q
G
K
Q
F
R
S
T
I
L
L
L
M
A
T
----
A
L
D
V
---T
S
E
L
R
V
R
Q
R
----
G
I
--
A
E
I
T
E
M
I
H
V
A
S
L
L
H
D
D
----------------
V
M
G
N
K
M
S
V
L
A
G
D
F
L
L
S
R
A
C
G
A
L
A
A
-
L
K
N
T
E
------
V
V
A
L
L
A
T
A
V
E
H
L
V
T
G
E
T
M
E
I
T
S
S
T
E
Q
R
Y
S
M
D
Y
Y
M
Q
K
T
Y
Y
K
T
A
S
L
I
S
N
S
C
K
A
V
A
V
L
T
G
---
Q
T
--
A
E
V
A
V
L
-
A
F
E
Y
G
R
N
L
G
L
A
F
Q
L
I
D
D
I
L
D
F
T
G
T
S
A
S
L
G
K
G
S
L
S
D
I
R
H
G
V
I
T
A
P
I
L
F
A
M
-----
E
E
F
----
P
Q
----------
L
R
------
E
V
V
D
Q
V
EKD-
P
-----
R
N
--
V
D
I
A
L
E
Y
L
--
G
K
S
K
G
I
Q
R
A
R
E
L
A
M
E
H
A
N
L
A
A
A
A
I
G
S
L
P
E
T
D
N
E
D
V
K
R
S
R
R
A
L
I
D
L
T
H
R
V
I
T
R
N
K