@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1838: (2015-12-11 )
MENLLQHKLPVAPFVESTTNWITKTFSGLFDFIQTIGNALMDWMTKTLLFINPLLFIVLITVAVFFLAKKKWQLPTFTFIGLLFIYNQGLWEQLINTFNLVLVASLISIIIGVPLGIWMAKSDKVKQVVNPILDFMQTMPAFVYLIPAVAFFGIGMVPGVFASVVFALPPTVRFTNLAIREIPLELIEASDSFGSTAKQKLFKVELPLAKNTIMAGINQTMMLALSMVVTGSMIGAPGLGREVLSALQHADIGTGFVSGLSLVILAIVLDRVSQFFNSKPGEKQAKTSKVKKWVGLGALVLFILAALGRIVVNMTSGNEAKGQKVKIAYVQWDSEVASTNVIAEVLKSKGYDVELTPLDNAVMWQTVANGNADFTTSAWLPKTHGQYFNKYKNSLDDLGPHVENVKIGLVVPKYMNVNSIEELSNQADKQITGIEPGAGIMKSAKQSLKDYPNLSSWKLLSASTGAMTTTLGKAIKNKDQVVITGWSPHWMFAKYDLKYLKDPKKSFGGEEHINTIARKNLKKDMPKVYKIIDKFKWTKEDMESIMLDMDKGMEPAKAAQKWIKNHKKEVSEWTK
Atome Classification :
(24 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.-......360........370.......380.......390-.-....-----...400------------........410...-------------..-----..420.....-----------..---430-----.-----------..--......----440.......450...-....-------460.......470.......480.......490...----....500......-----------------.---510-------------------........520.......530.......540...--...-.550-.----......---.560.......570...---------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
E
N
L
L
Q
HKLPVA
P
F
V
E
S
T
T
N
W
I
T
K
T
F
S
G
L
F
D
F
I
Q
T
I
G
N
A
L
M
D
W
M
T
K
T
L
L
F
I
N
P
L
L
F
I
V
L
I
T
V
A
V
F
F
L
A
KKKWQL
P
T
F
T
F
I
G
L
L
F
I
YNQ
G
L
W
E
Q
L
I
N
T
F
N
L
V
L
V
A
S
L
I
S
I
I
I
GVPL
G
I
W
MAK
S
D
K
V
K
Q
V
V
N
P
I
L
D
F
M
Q
T
M
P
A
F
V
Y
L
I
P
A
V
A
F
F
G
IGM
V
P
G
V
F
A
S
V
V
F
ALPPT
V
R
F
T
N
L
A
I
R
EI
P
L
E
L
I
EASDSFG
S
T
A
K
Q
K
L
F
K
V
ELPLA
K
N
T
I
M
A
G
I
N
Q
T
M
M
L
A
L
S
M
V
V
TGSMIGAPGL
G
R
E
V
L
S
A
L
QHADI
G
T
G
F
V
S
G
L
S
L
V
I
L
A
I
V
L
D
R
V
S
Q
F
F
NSKPGE
K
Q
A
K
T
S
K
V
K
K
W
V
G
L
G
A
L
V
L
F
I
L
A
A
L
G
R
I
V
V
N
MTSGNEAKG
Q
K
V
K
I
A
Y
V
Q
WDSEVA
S
T
N
V
I
A
E
V
L
KSKGY
D
V
-
E
L
T
PLDN-
A
V
M
W
Q
T
VANGNADFTTSAWLPK
T
H
G
Q
Y
F
N
K
Y
--
K
-
N
S
L
D
-----DLGPH-------------VEN
V
K
I
G
L
V
VPKYM-------------NV-----
N
S
I
E
E
L
S
N
QA-----------DK---Q-------I-----------TG--IEPG
A
G
----
I
M
K
S
A
K
Q
S
L
K
DYPNLS-S
W
K
L
-------
L
SASTG
A
M
T
T
T
L
G
K
AIKNKD
Q
V
V
I
TGWSP
H
W
M
F
A
KY----
D
L
K
Y
LK
D
P
K
K
SFG-----------------
G
---
E
E
--------------------
H
I
N
T
I
A
R
K
N
L
K
K
D
M
P
K
V
Y
K
I
I
D
K
FKW
T
K
E
D
M
E
S
I
--
M
L
D
-
M
D-K-G----M
E
P
A
K
A
---
A
Q
K
W
I
K
N
H
K
K
E
V
S
E
WTK---------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
95.47
58%
-68
- C3 -
3L6H
3
?
A:
[2-254]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
V
D
L
V
Y
M
N
W
D
S
E
V
A
S
I
N
V
L
T
Q
A
M
K
E
H
G
F
D
V
-
K
T
T
A
L
D
N
-
A
V
A
W
Q
T
V
A
N
G
Q
A
D
G
M
V
S
A
W
L
P
N
T
H
K
T
Q
W
Q
K
Y
--
G
-
K
S
V
D
-----
L
L
G
P
N
-------------
L
K
G
A
K
V
G
F
V
V
P
S
Y
M
-------------
N
V
-----
N
S
I
E
D
L
T
N
Q
A
-----------
N
K
---
T
-------
I
-----------
T
G
--
I
E
P
G
A
G
----
V
M
A
A
S
E
K
T
L
N
S
Y
D
N
L
K
-
D
W
K
L
-------
V
P
S
S
S
G
A
M
T
V
A
L
G
E
A
I
K
Q
H
K
D
I
V
I
T
G
W
S
P
H
W
M
F
N
K
Y
----
D
L
K
Y
L
A
D
P
K
G
T
M
G
-----------------
T
---
S
E
--------------------
N
I
N
T
I
V
R
K
G
L
K
K
E
N
P
E
A
Y
K
V
L
D
K
F
N
W
T
T
K
D
M
E
A
V
--
M
L
D
-
I
Q
-
N
-
G
----
K
T
P
E
E
A
---
A
K
N
W
I
K
D
H
Q
K
E
V
D
K
W
F
K
---------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
94.97
58%
-69
- C3 -
3L6G
1
?
A:
[2-254]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
V
D
L
V
Y
M
N
W
D
S
E
V
A
S
I
N
V
L
T
Q
A
M
K
E
H
G
F
D
V
-
K
T
T
A
L
D
N
-
A
V
A
W
Q
T
V
A
N
G
Q
A
D
G
M
V
S
A
W
L
P
N
T
H
K
T
Q
W
Q
K
Y
--
G
-
K
S
V
D
-----
L
L
G
P
N
-------------
L
K
G
A
K
V
G
F
V
V
P
S
Y
M
-------------
N
V
-----
N
S
I
E
D
L
T
N
Q
A
-----------
N
K
---
T
-------
I
-----------
T
G
--
I
E
P
G
A
G
----
V
M
A
A
S
E
K
T
L
N
S
Y
D
N
L
K
-
D
W
K
L
-------
V
P
S
S
S
G
A
M
T
V
A
L
G
E
A
I
K
Q
H
K
D
I
V
I
T
G
W
S
P
H
W
M
F
N
K
Y
----
D
L
K
Y
L
A
D
P
K
G
T
M
G
-----------------
T
---
S
E
--------------------
N
I
N
T
I
V
R
K
G
L
K
K
E
N
P
E
A
Y
K
V
L
D
K
F
N
W
T
T
K
D
M
E
A
V
--
M
L
D
-
I
Q
-
N
-
G
----
K
T
P
E
E
A
---
A
K
N
W
I
K
D
H
Q
K
E
V
D
K
W
F
K
---------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
87.46
34%
-60
- C3 -
3TMG
2
?
C:
[16-270]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
S
V
K
I
G
Y
V
N
W
G
G
E
T
A
A
T
N
V
L
K
V
V
F
E
K
M
G
Y
N
A
-
E
I
F
S
V
T
T
-
S
I
M
Y
Q
Y
L
A
S
G
K
I
D
G
T
V
S
S
W
V
P
T
A
D
K
F
Y
Y
E
K
L
--
K
-
T
K
F
V
-----
D
L
G
A
N
-------------
Y
E
G
T
I
Q
G
F
V
V
P
S
Y
V
-------------
P
I
-----
S
S
I
S
E
L
K
G
K
G
-----------
D
K
FKN
K
-------
M
-----------
I
G
--
I
D
A
G
A
G
----
T
Q
I
V
T
E
Q
A
L
N
Y
Y
G
L
S
K
-
E
Y
E
L
-------
V
P
S
S
E
S
V
M
L
A
S
L
D
S
S
I
K
R
N
E
W
I
L
V
P
L
W
K
P
H
W
A
F
S
R
Y
----
D
I
K
F
L
D
D
P
D
L
I
M
G
-----------------
G
---
I
E
--------------------
S
V
H
T
L
V
R
L
G
L
E
N
D
D
F
D
A
Y
Y
V
F
D
H
F
Y
W
S
D
D
L
I
L
P
L
--
M
D
K
-
N
D
-
K
-------
E
P
G
K
E
YRN
A
V
E
F
V
E
K
N
K
E
I
V
K
T
W
V
P
---------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
86.76
34%
-61
- C3 -
3TMG
2
?
A:
[16-270]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
S
V
K
I
G
Y
V
N
W
G
G
E
T
A
A
T
N
V
L
K
V
V
F
E
K
M
G
Y
N
A
-
E
I
F
S
V
T
T
-
S
I
M
Y
Q
Y
L
A
S
G
K
I
D
G
T
V
S
S
W
V
P
T
A
D
K
F
Y
Y
E
K
L
--
K
-
T
K
F
V
-----
D
L
G
A
N
-------------
Y
E
G
T
I
Q
G
F
V
V
P
S
Y
V
-------------
P
I
-----
S
S
I
S
E
L
K
G
K
G
-----------
D
K
FKN
K
-------
M
-----------
I
G
--
I
D
A
G
A
G
----
T
Q
I
V
T
E
Q
A
L
N
Y
Y
G
L
S
K
-
E
Y
E
L
-------
V
P
S
S
E
S
V
M
L
A
S
L
D
S
S
I
K
R
N
E
W
I
L
V
P
L
W
K
P
H
W
A
F
S
R
Y
----
D
I
K
F
L
D
D
P
D
L
I
M
G
-----------------
G
---
I
E
--------------------
S
V
H
T
L
V
R
L
G
L
E
N
D
D
F
D
A
Y
Y
V
F
D
H
F
Y
W
S
D
D
L
I
L
P
L
--
M
D
K
-
N
D
-
K
-------
E
P
G
K
E
Y
R
N
A
V
E
F
V
E
K
N
K
E
I
V
K
T
W
V
P
---------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
86.53
34%
-64
- C3 -
3TMG
3
?
D:
[16-270]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
S
V
K
I
G
Y
V
N
W
G
G
E
T
A
A
T
N
V
L
K
V
V
F
E
K
M
G
Y
N
A
-
E
I
F
S
V
T
T
-
S
I
M
Y
Q
Y
L
A
S
G
K
I
D
G
T
V
S
S
W
V
P
T
A
D
K
F
Y
Y
E
K
L
--
K
-
T
K
F
V
-----
D
L
G
A
N
-------------
Y
E
G
T
I
Q
G
F
V
V
P
S
Y
V
-------------
P
I
-----
S
S
I
S
E
L
K
G
K
G
-----------
D
K
FKN
K
-------
M
-----------
I
G
--
I
D
A
G
A
G
----
T
Q
I
V
T
E
Q
A
L
N
Y
Y
G
L
S
K
-
E
Y
E
L
-------
V
P
S
S
E
S
V
M
L
A
S
L
D
S
S
I
K
R
N
E
W
I
L
V
P
L
W
K
P
H
W
A
F
S
R
Y
----
D
I
K
F
L
D
D
P
D
L
I
M
G
-----------------
G
---
I
E
--------------------
S
V
H
T
L
V
R
L
G
L
E
N
D
D
F
D
A
Y
Y
V
F
D
H
F
Y
W
S
D
D
L
I
L
P
L
--
M
D
K
-
N
D
-
K
-------
E
P
G
K
E
YRN
A
V
E
F
V
E
K
N
K
E
I
V
K
T
W
V
P
---------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
86.20
34%
-58
- C3 -
3TMG
2
?
B:
[16-270]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
S
V
K
I
G
Y
V
N
W
G
G
E
T
A
A
T
N
V
L
K
V
V
F
E
K
M
G
Y
N
A
-
E
I
F
S
V
T
T
-
S
I
M
Y
Q
Y
L
A
S
G
K
I
D
G
T
V
S
S
W
V
P
T
A
D
K
F
Y
Y
E
K
L
--
K
-
T
K
F
V
-----
D
L
G
A
N
-------------
Y
E
G
T
I
Q
G
F
V
V
P
S
Y
V
-------------
P
I
-----
S
S
I
S
E
L
K
G
K
G
-----------
D
K
FKN
K
-------
M
-----------
I
G
--
I
D
A
G
A
G
----
T
Q
I
V
T
E
Q
A
L
N
Y
Y
G
L
S
K
-
E
Y
E
L
-------
V
P
S
S
E
S
V
M
L
A
S
L
D
S
S
I
K
R
N
E
W
I
L
V
P
L
W
K
P
H
W
A
F
S
R
Y
----
D
I
K
F
L
D
D
P
D
L
I
M
G
-----------------
G
---
I
E
--------------------
S
V
H
T
L
V
R
L
G
L
E
N
D
D
F
D
A
Y
Y
V
F
D
H
F
Y
W
S
D
D
L
I
L
P
L
--
M
D
K
-
N
D
-
K
-------
E
P
G
K
E
Y
R
N
A
V
E
F
V
E
K
N
K
E
I
V
K
T
W
V
P
---------------------------------------------------------------------------------------------------------------
28
HHSearch
84.23
31%
-54
- C3 -
3TMG
2
?
A:
[15-272]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
S
V
K
I
G
Y
V
N
W
G
G
E
T
A
A
T
N
V
L
K
V
V
F
E
K
M
G
Y
N
A
-
E
I
F
S
V
T
T
-
S
I
M
Y
Q
Y
L
A
S
G
K
I
D
G
T
V
S
S
W
V
P
T
A
D
K
F
Y
Y
E
K
L
--
K
-
T
K
F
V
-----
D
L
G
A
N
-------------
Y
E
G
T
I
Q
G
F
V
V
P
S
Y
V
-------------
P
I
-----
S
S
I
S
E
L
---------------
K
G
---
K
GDKFKN
K
M
-----------
I
G
--
I
D
A
G
A
G
----
T
Q
I
V
T
E
Q
A
L
N
Y
Y
G
L
S
K
-
E
Y
E
L
-------
V
P
S
S
E
S
V
M
L
A
S
L
D
S
S
I
K
R
N
E
W
I
L
V
P
L
W
K
P
H
W
A
F
S
R
Y
----
D
I
K
F
L
D
D
P
D
L
I
M
G
-----------------
G
---
I
E
--------------------
S
V
H
T
L
V
R
L
G
L
E
N
D
D
F
D
A
Y
Y
V
F
D
H
F
Y
W
S
D
D
L
I
L
P
L
--
M
D
K
-
N
D
K
E
-
P
----
G
K
E
Y
R
N
---
A
V
E
F
V
E
K
N
K
E
I
V
K
T
W
V
P
---------------------------------------------------------------------------------------------------------------
48
Fugue
72.05
21%
-38
- C3 -
1R9L
2
PROX_ECOLI
A:
[1-309]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
L
P
G
K
G
I
T
V
N
P
V
Q
S
T
I
T
E
E
T
F
Q
T
L
L
V
S
R
A
L
E
K
L
G
Y
T
V
N
K
P
S
E
V
D
Y
-
N
V
G
Y
T
S
L
A
S
G
D
A
T
F
T
A
V
N
W
T
P
-
L
H
D
N
M
Y
E
A
A
GG
D
-
K
K
F
Y
-----
R
E
G
V
F
-------------
V
N
G
A
A
Q
G
Y
L
I
D
K
K
T
A
D
Q
Y
---------
K
I
-----
T
N
I
A
Q
L
K
D
P
K
-----------
I
A
---
K
-------
L
F
DTNGDG
K
A
D
L
T
G
--
C
N
P
G
W
G
----
C
E
G
A
I
N
H
Q
L
A
A
Y
E
L
T
N
-
T
V
T
H
-------
N
Q
G
N
Y
A
A
M
M
A
D
T
I
S
R
Y
K
E
G
K
P
V
F
Y
Y
T
W
T
P
Y
W
V
S
N
E
L
KPGK
D
V
V
W
L
Q
V
P
F
S
A
L
P
-----------------
G
---
D
K
NADTKLPNGANYGFPV
S
---
T
M
H
I
V
A
N
K
A
W
A
E
K
N
P
A
A
A
K
L
F
A
I
M
Q
L
P
V
A
D
I
N
A
Q
--
N
A
I
-
M
H
-
D
-
G
KAS
E
G
D
I
Q
G
H
---
V
D
G
W
I
K
A
H
Q
Q
Q
F
D
G
W
V
N
E
A
L
A
AQK--------------------------------------------------------------------------------------------------------
50
Fugue
72.01
45%
-39
- C3 -
2B4L
10
OPUAC_BACSU
A:
[1-268]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
N
A
S
A
A
E
Q
V
-----------
N
K
---
T
-------
I
-----------
I
G
--
I
D
P
G
S
G
----
I
M
S
L
T
D
K
A
M
K
D
Y
-
D
L
N
-
D
W
T
L
-------
I
S
A
S
S
A
A
M
T
A
T
L
K
K
S
Y
D
R
K
K
P
I
I
I
T
G
W
T
P
H
W
M
F
S
R
Y
----
K
L
K
Y
L
D
D
P
K
Q
S
Y
G
-----------------
S
---
A
E
--------------------
E
I
H
T
I
T
R
K
G
F
S
K
E
Q
P
N
A
A
K
L
L
S
Q
F
K
W
T
Q
D
E
M
G
E
I
--
M
I
K
-
V
E
-
E
-
G
----
E
K
P
A
K
V
---
A
A
E
Y
V
N
K
H
K
D
Q
I
A
E
W
T
K
G
V
Q
K
V
K
G
D
K
I
N
L
A
Y
V
AW
D
S
E
I
A
S
T
N
V
I
G
K
V
L
E
D
L
GYE
V
T
L
T
Q
V
E
A
G
P
M
W
T
A
I
A
T
GSADASLSAWLPNTH
K
A
Y
A
A
K
Y
KGKYDDIGTSMTGVKM
G
L
V
V
P
QYMKNVNS
I
E
D
L
K
K
29
HHSearch
70.82
20%
-32
- C3 -
1R9L
2
PROX_ECOLI
A:
[4-302]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
G
K
G
I
T
V
N
P
V
Q
S
T
I
T
E
E
T
F
Q
T
L
L
V
S
R
A
L
E
K
L
G
Y
T
V
-
N
K
P
S
E
V
D
Y
N
V
G
Y
T
S
L
A
S
G
D
A
T
F
T
A
V
N
W
T
P
L
H
-
D
N
M
Y
E
A
A
GG
D
-
K
K
F
Y
-----
R
E
G
V
F
-------------
V
N
G
A
A
Q
G
Y
L
I
D
K
K
T
A
D
Q
Y
---------
K
I
-----
T
N
I
A
Q
L
K
D
P
K
I
A
K
L
F
DTNGDG
K
A
---
D
-------
L
-----------
T
G
--
C
N
P
G
W
G
----
C
E
G
A
I
N
H
Q
L
A
A
Y
E
L
T
N
-
T
V
T
H
-------
N
Q
G
N
Y
A
A
M
M
A
D
T
I
S
R
Y
K
E
G
K
P
V
F
Y
Y
T
W
T
P
Y
W
V
S
N
E
L
KPGK
D
V
V
W
L
Q
V
P
F
S
A
L
P
GDKNADTKLPNGANYGF
P
---
V
S
--------------------
T
M
H
I
V
A
N
K
A
W
A
E
K
N
P
A
A
A
K
L
F
A
I
M
Q
L
P
V
A
D
I
N
A
Q
--
N
A
I
-
M
H
-
D
G
K
AS
E
-
G
D
I
Q
G
H
---
V
D
G
W
I
K
A
H
Q
Q
Q
F
D
G
W
V
N
---------------------------------------------------------------------------------------------------------------
32
HHSearch
69.89
22%
-47
- C3 -
2RIN
1
?
A:
[4-271]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
S
C
G
T
V
R
F
S
D
V
G
W
T
D
I
T
A
T
T
A
T
A
T
T
I
L
E
A
L
G
Y
E
T
-
D
V
K
V
L
S
V
-
P
V
T
Y
T
S
L
K
N
K
D
I
D
V
F
L
G
N
W
M
P
T
M
-
E
A
D
I
A
P
Y
R
E
D
-
K
S
V
E
-----
T
V
R
E
N
-------------
L
A
G
A
K
Y
T
L
A
T
N
A
K
G
A
E
L
----------
G
I
-----
K
D
F
K
D
I
A
A
H
K
DEL--------
D
G
---
K
-------
I
-----------
Y
G
--
I
E
P
G
N
D
----
G
N
R
L
I
I
D
M
V
E
K
G
T
F
D
L
K
G
F
E
V
-------
V
E
S
S
E
Q
G
M
L
A
Q
V
A
R
A
E
K
S
G
D
P
I
V
F
L
G
W
E
P
H
P
M
N
A
N
F
----
K
L
T
Y
L
S
G
G
D
D
V
F
G
-----------------
P
NYG
G
A
--------------------
T
V
H
T
N
V
R
A
G
Y
T
T
E
C
P
N
V
D
K
L
L
Q
N
L
S
F
S
L
Q
M
E
N
E
I
--
M
G
K
-
I
L
-
N
D
G
----
E
D
P
E
K
A
---
A
A
A
W
L
K
D
N
P
Q
S
I
E
P
W
L
S
---------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
69.10
24%
-47
- C3 -
2REG
1
?
A:
[9-269]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
F
S
D
V
G
W
T
D
I
T
A
T
T
A
T
A
T
T
I
L
E
A
L
G
Y
E
T
-
D
V
K
V
L
S
V
-
P
V
T
Y
T
S
L
K
N
K
D
I
D
V
F
L
G
N
W
M
P
T
M
E
A
-------------------
D
I
A
P
Y
R
E
D
KS--------
V
E
T
V
R
E
N
L
A
G
A
K
Y
T
L
ATN
A
K
G
A
E
L
GIK
D
F
-----
K
D
I
A
A
H
K
D
E
L
-----------
D
G
---
K
-------
I
-----------
Y
G
--
I
E
P
G
N
D
G
N
R
L
I
I
D
M
V
E
K
G
T
F
D
---
L
K
-
G
F
E
V
-------
V
E
S
S
E
Q
G
M
L
A
Q
V
A
R
A
E
K
S
G
D
P
I
V
F
L
G
W
E
P
H
P
M
N
A
N
F
----
K
L
T
Y
L
S
G
G
D
D
V
F
G
PNY--------------
G
---
G
A
--------------------
T
V
H
T
N
V
R
A
G
Y
T
T
E
C
P
N
V
D
K
L
L
Q
N
L
S
F
S
L
Q
M
E
N
E
I
--
M
G
K
I
L
N
-
D
-
G
----
E
D
P
E
K
A
---
A
A
A
W
L
K
D
N
P
Q
S
I
E
P
W
L
S
---------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
66.84
24%
-43
- C3 -
2RIN
1
?
A:
[9-269]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
F
S
D
V
G
W
T
D
I
T
A
T
T
A
T
A
T
T
I
L
E
A
L
G
Y
E
T
-
D
V
K
V
L
S
V
-
P
V
T
Y
T
S
L
K
N
K
D
I
D
V
F
L
G
N
W
M
P
T
M
E
A
-------------------
D
I
A
P
Y
R
E
D
KS--------
V
E
T
V
R
E
N
L
A
G
A
K
Y
T
L
A
T
N
A
K
G
A
E
L
GIK
D
F
-----
K
D
I
A
A
H
K
D
E
L
-----------
D
G
---
K
-------
I
-----------
Y
G
--
I
E
P
G
N
D
G
N
R
L
I
I
D
M
V
E
K
G
T
F
D
---
L
K
-
G
F
E
V
-------
V
E
S
S
E
Q
G
M
L
A
Q
V
A
R
A
E
K
S
G
D
P
I
V
F
L
G
W
E
P
H
P
M
N
A
N
F
----
K
L
T
Y
L
S
G
G
D
D
V
F
G
PNY--------------
G
---
G
A
--------------------
T
V
H
T
N
V
R
A
G
Y
T
T
E
C
P
N
V
D
K
L
L
Q
N
L
S
F
S
L
Q
M
E
N
E
I
--
M
G
K
I
L
N
-
D
-
G
----
E
D
P
E
K
A
---
A
A
A
W
L
K
D
N
P
Q
S
I
E
P
W
L
S
---------------------------------------------------------------------------------------------------------------
51
Fugue
66.22
17%
-35
- C3 -
4XZ6
4
?
A:
[43-333]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
S
S
D
P
I
V
I
P
I
H
N
W
S
S
Q
I
V
M
S
N
V
V
G
Q
I
F
E
E
M
G
V
A
V
-
E
F
V
T
T
D
S
-
Q
A
V
Y
E
S
V
R
L
G
D
V
T
L
E
L
E
V
W
E
G
A
F
G
A
S
F
R
A
A
L
--
E
K
G
G
I
V
-----
D
V
G
D
H
-------------
D
A
V
T
R
E
D
W
W
Y
P
M
W
T
-------------
K
D
ACPGL
P
D
W
K
A
L
N
D
C
A
-----------
A
V
---
F
-------
A
-----------
T
A
--
E
T
G
D
K
G
----
R
Y
L
D
G
P
V
D
W
L
K
H
G
K
E
R
-
V
E
A
L
GMN
F
E
V
I
N
A
G
S
A
A
A
L
W
A
E
I
G
A
A
E
A
D
K
R
P
V
V
V
F
N
W
T
P
N
F
A
E
A
V
W
----
P
G
E
F
V
E
F
P
E
W
V
D
G
-----------------
C
---
D
K
DPAVGPNPDALYDCGNPAT
G
Y
L
K
K
A
A
W
E
G
M
E
A
K
W
P
D
A
Y
A
V
L
T
R
I
S
F
T
N
P
Q
I
A
E
M
--
A
K
L
-
V
D
V
D
-
E
----
M
E
P
D
E
A
---
A
E
A
W
L
E
A
N
E
D
V
W
R
P
W
L
D
G--------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
65.97
24%
-40
- C3 -
2RF1
-
?
A:
[36-296]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
F
S
D
V
G
W
T
D
I
T
A
T
T
A
T
A
T
T
I
L
E
A
L
G
Y
E
T
-
D
V
K
V
L
S
V
-
P
V
T
Y
T
S
L
K
N
K
D
I
D
V
F
L
G
N
W
M
P
T
M
E
A
-------------------
D
I
A
P
Y
R
E
D
KS--------
V
E
T
V
R
E
N
L
A
G
A
K
Y
T
L
A
T
N
A
K
G
A
E
L
GIK
D
F
-----
K
D
I
A
A
H
K
D
E
L
-----------
D
G
---
K
-------
I
-----------
Y
G
--
I
E
P
G
N
D
G
N
R
L
I
I
D
M
V
E
K
G
T
F
D
---
L
K
-
G
F
E
V
-------
V
E
S
S
E
Q
G
M
L
A
Q
V
A
R
A
E
K
S
G
D
P
I
V
F
L
G
W
E
P
H
P
M
N
A
N
F
----
K
L
T
Y
L
S
G
G
D
D
V
F
G
PNY--------------
G
---
G
A
--------------------
T
V
H
T
N
V
R
A
G
Y
T
T
E
C
P
N
V
D
K
L
L
Q
N
L
S
F
S
L
Q
M
E
N
E
I
--
M
G
K
I
L
N
-
D
-
G
----
E
D
P
E
K
A
---
A
A
A
W
L
K
D
N
P
Q
S
I
E
P
W
L
S
---------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
65.20
47%
-50
- C3 -
2B4M
1
OPUAC_BACSU
A:
[7-157]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
E
Q
V
-----------
N
K
---
T
-------
I
-----------
I
G
--
I
D
P
G
S
G
----
I
M
S
L
T
D
K
A
M
K
D
Y
-
D
L
N
-
D
W
T
L
-------
I
S
A
S
S
A
A
M
T
A
T
L
K
K
S
Y
D
R
K
K
P
I
I
I
T
G
W
T
P
H
W
M
F
S
R
Y
----
K
L
K
Y
L
D
D
P
K
Q
S
Y
G
-----------------
S
---
A
E
--------------------
E
I
H
T
I
T
R
K
G
F
S
K
E
Q
P
N
A
A
K
L
L
S
Q
F
K
W
T
Q
D
E
M
G
E
I
--
M
I
K
-
V
E
-
E
-
G
----
E
K
P
A
K
V
---
A
A
E
Y
V
N
K
H
K
D
Q
I
A
E
W
T
K
---------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
64.83
47%
-50
- C3 -
2B4M
1
OPUAC_BACSU
B:
[7-157]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
E
Q
V
-----------
N
K
---
T
-------
I
-----------
I
G
--
I
D
P
G
S
G
----
I
M
S
L
T
D
K
A
M
K
D
Y
-
D
L
N
-
D
W
T
L
-------
I
S
A
S
S
A
A
M
T
A
T
L
K
K
S
Y
D
R
K
K
P
I
I
I
T
G
W
T
P
H
W
M
F
S
R
Y
----
K
L
K
Y
L
D
D
P
K
Q
S
Y
G
-----------------
S
---
A
E
--------------------
E
I
H
T
I
T
R
K
G
F
S
K
E
Q
P
N
A
A
K
L
L
S
Q
F
K
W
T
Q
D
E
M
G
E
I
--
M
I
K
-
V
E
-
E
-
G
----
E
K
P
A
K
V
---
A
A
E
Y
V
N
K
H
K
D
Q
I
A
E
W
T
K
---------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
64.41
47%
-42
- C3 -
2B4L
8
OPUAC_BACSU
A:
[7-157]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
E
Q
V
-----------
N
K
---
T
-------
I
-----------
I
G
--
I
D
P
G
S
G
----
I
M
S
L
T
D
K
A
M
K
D
Y
-
D
L
N
-
D
W
T
L
-------
I
S
A
S
S
A
A
M
T
A
T
L
K
K
S
Y
D
R
K
K
P
I
I
I
T
G
W
T
P
H
W
M
F
S
R
Y
----
K
L
K
Y
L
D
D
P
K
Q
S
Y
G
-----------------
S
---
A
E
--------------------
E
I
H
T
I
T
R
K
G
F
S
K
E
Q
P
N
A
A
K
L
L
S
Q
F
K
W
T
Q
D
E
M
G
E
I
--
M
I
K
-
V
E
-
E
-
G
----
E
K
P
A
K
V
---
A
A
E
Y
V
N
K
H
K
D
Q
I
A
E
W
T
K
---------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
64.09
17%
-30
- C3 -
4XZ6
4
?
A:
[54-330]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
W
S
S
Q
I
V
M
S
N
V
V
G
Q
I
F
E
E
M
G
V
A
V
-
E
F
V
T
T
D
S
-
Q
A
V
Y
E
S
V
R
L
G
D
V
T
L
E
L
E
V
W
----
E
G
A
F
G
A
S
F
--
R
-
A
A
L
E
K
GGIV
D
V
G
D
H
D
A
V
T
R
E
D
W
W
Y
P
MW
T
K
D
A
C
P
G
L
--
P
D
W
K
-------------
A
L
-----
N
D
C
A
A
V
F
A
T
A
-----------
E
T
---
G
-------
D
-----------
K
G
R
Y
L
D
G
P
V
D
----
W
L
K
H
G
K
E
R
V
E
A
L
-
G
M
N
-
F
E
V
I
-------
N
A
G
S
A
A
A
L
W
A
E
I
G
A
A
E
A
D
K
R
P
V
V
V
F
N
W
T
P
N
F
A
E
A
V
W
----
P
G
E
F
V
E
F
P
E
W
V
D
G
-----------------
C
---
D
K
DPAVGPNPDALYDCGNPAT
G
Y
L
K
K
A
A
W
E
G
M
E
A
K
W
P
D
A
Y
A
V
L
T
R
I
S
F
T
N
P
Q
I
A
E
M
A
K
L
V
D
-
V
D
-
E
------
M
E
P
D
E
A
---
A
E
A
W
L
E
A
N
E
D
V
W
R
P
W
L
D
---------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
63.90
47%
-50
- C3 -
3CHG
1
OPUAC_BACSU
B:
[11-157]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
K
---
T
-------
I
-----------
I
G
--
I
D
P
G
S
G
----
I
M
S
L
T
D
K
A
M
K
D
Y
-
D
L
N
-
D
W
T
L
-------
I
S
A
S
S
A
A
M
T
A
T
L
K
K
S
Y
D
R
K
K
P
I
I
I
T
G
W
T
P
H
W
M
F
S
R
Y
----
K
L
K
Y
L
D
D
P
K
Q
S
Y
G
-----------------
S
---
A
E
--------------------
E
I
H
T
I
T
R
K
G
F
S
K
E
Q
P
N
A
A
K
L
L
S
Q
F
K
W
T
Q
D
E
M
G
E
I
--
M
I
K
-
V
E
-
E
-
G
----
E
K
P
A
K
V
---
A
A
E
Y
V
N
K
H
K
D
Q
I
A
E
W
T
K
---------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
63.14
47%
-48
- C3 -
3CHG
1
OPUAC_BACSU
C:
[11-157]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
K
---
T
-------
I
-----------
I
G
--
I
D
P
G
S
G
----
I
M
S
L
T
D
K
A
M
K
D
Y
-
D
L
N
-
D
W
T
L
-------
I
S
A
S
S
A
A
M
T
A
T
L
K
K
S
Y
D
R
K
K
P
I
I
I
T
G
W
T
P
H
W
M
F
S
R
Y
----
K
L
K
Y
L
D
D
P
K
Q
S
Y
G
-----------------
S
---
A
E
--------------------
E
I
H
T
I
T
R
K
G
F
S
K
E
Q
P
N
A
A
K
L
L
S
Q
F
K
W
T
Q
D
E
M
G
E
I
--
M
I
K
-
V
E
-
E
-
G
----
E
K
P
A
K
V
---
A
A
E
Y
V
N
K
H
K
D
Q
I
A
E
W
T
K
---------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
63.04
47%
-45
- C3 -
3CHG
1
OPUAC_BACSU
D:
[12-157]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
---
T
-------
I
-----------
I
G
--
I
D
P
G
S
G
----
I
M
S
L
T
D
K
A
M
K
D
Y
-
D
L
N
-
D
W
T
L
-------
I
S
A
S
S
A
A
M
T
A
T
L
K
K
S
Y
D
R
K
K
P
I
I
I
T
G
W
T
P
H
W
M
F
S
R
Y
----
K
L
K
Y
L
D
D
P
K
Q
S
Y
G
-----------------
S
---
A
E
--------------------
E
I
H
T
I
T
R
K
G
F
S
K
E
Q
P
N
A
A
K
L
L
S
Q
F
K
W
T
Q
D
E
M
G
E
I
--
M
I
K
-
V
E
-
E
-
G
----
E
K
P
A
K
V
---
A
A
E
Y
V
N
K
H
K
D
Q
I
A
E
W
T
K
---------------------------------------------------------------------------------------------------------------
40
HHSearch
62.78
47%
-40
- C3 -
2B4L
8
OPUAC_BACSU
A:
[7-157]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
E
Q
V
---------------
N
K
---
T
-------
I
-----------
I
G
--
I
D
P
G
S
G
----
I
M
S
L
T
D
K
A
M
K
D
Y
D
L
N
--
D
W
T
L
-------
I
S
A
S
S
A
A
M
T
A
T
L
K
K
S
Y
D
R
K
K
P
I
I
I
T
G
W
T
P
H
W
M
F
S
R
Y
----
K
L
K
Y
L
D
D
P
K
Q
S
Y
G
-----------------
S
---
A
E
--------------------
E
I
H
T
I
T
R
K
G
F
S
K
E
Q
P
N
A
A
K
L
L
S
Q
F
K
W
T
Q
D
E
M
G
E
I
--
M
I
K
-
V
E
-
E
-
G
----
E
K
P
A
K
V
---
A
A
E
Y
V
N
K
H
K
D
Q
I
A
E
W
T
K
---------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
61.94
47%
-43
- C3 -
3CHG
1
OPUAC_BACSU
A:
[11-157]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
K
---
T
-------
I
-----------
I
G
--
I
D
P
G
S
G
----
I
M
S
L
T
D
K
A
M
K
D
Y
-
D
L
N
-
D
W
T
L
-------
I
S
A
S
S
A
A
M
T
A
T
L
K
K
S
Y
D
R
K
K
P
I
I
I
T
G
W
T
P
H
W
M
F
S
R
Y
----
K
L
K
Y
L
D
D
P
K
Q
S
Y
G
-----------------
S
---
A
E
--------------------
E
I
H
T
I
T
R
K
G
F
S
K
E
Q
P
N
A
A
K
L
L
S
Q
F
K
W
T
Q
D
E
M
G
E
I
--
M
I
K
-
V
E
-
E
-
G
----
E
K
P
A
K
V
---
A
A
E
Y
V
N
K
H
K
D
Q
I
A
E
W
T
K
---------------------------------------------------------------------------------------------------------------