@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1884: (2015-12-11 )
MSKKMTINDIAQLSKTSKTTVSFFLNQKFEKMSDETRQRIQEVIDETGYRPSTIARSLNSKKTKLLGVLIGDITNTFSNQIVKGIEHITKQKGYQIIVGNSNYDAKSEEDYIENMLNLGVDGFIIQPTSNFRKYSRILKEKKKPMVFFDSQLYEHKTSWVKANNYDAVYDMTQECLNRGYKKFIMITADTSLLSTRIERASGFMDALKDNGFGYDTLVIEDDDHSKSDIEDFLKAVVPDKEETLVFAPNCWALPMVFTAMKNLNFDMPRVGLVGFDNIEWTDFSSPKVSTIVQPAYEEGEQVAQILINRIEGDDSVDNQQIVDCQMFWKESTF
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90.........100.......110...-....120...-....130.......-140.-......-150..-.....160---.......170.......180.......190..-.....200.......210..-.....220..----.-....230.......240-....-...250........260.......-270.......280-.......290..-.....300..-.....310...-.....320........330.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MSKKM
T
I
N
D
I
A
Q
L
SKTSK
T
T
V
S
F
F
L
N
Q
K
F
E
K
M
S
D
E
T
R
Q
R
I
Q
E
V
I
D
ETGY
R
P
S
T
I
A
R
S
LNSK
K
T
K
L
L
G
V
L
I
G
D
I
T
N
T
F
S
N
Q
I
V
K
G
I
E
H
I
T
K
-QKG
Y
Q
I
I
V
GNSNYDAK
S
E
E
D
Y
I
E
N
M
-
L
NLGVD
G
F
I
I-QPTS
N
F
R
K
Y
S
R
I
L
K
-EKKK-
P
M
V
F
FD-
S
Q
L
Y
E
-HKT
S
W
V
KA---NNY
D
A
V
Y
D
M
T
Q
E
C
L
N
RGY
K
K
F
I
M
I
TA
D
T
S
L
L
S
-
T
R
I
E
R
A
S
G
F
M
D
A
L
KDNGFG
Y
-
D
T
L
V
I
EDDDH----
S
-
K
S
D
I
E
D
F
L
K
A
VVPDKEE-
T
L
V
F-APNCW-
A
L
P
M
V
F
T
A
M
K
NLNFDMPR-VG
L
V
GFDNIEWTD-FSSPK
V
S
T
I
VQ
P
-
A
Y
EE
G
E
Q
V
A
Q
-
I
L
I
N
RI-EGDD-SVDN
Q
Q
I
-
V
D
C
Q
M
F
WKESTF
3
PsiBlast_PDB
93.33
27%
-73
- C3 -
1RZR
6
CCPA_BACME
G:
[3-331]
----
V
T
I
Y
D
V
A
R
E
A
S
V
S
M
A
T
V
S
R
V
V
N
G
N
-
P
N
V
K
P
S
T
R
K
K
V
L
E
T
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
K
K
T
T
T
V
G
V
I
I
P
D
I
S
N
I
F
Y
A
E
L
A
R
G
I
E
D
I
A
T
-
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
Q
D
K
E
L
H
L
L
N
N
M
-
L
G
K
Q
V
D
G
I
I
F
-
M
S
G
N
V
T
E
E
H
V
E
E
L
K
-
K
S
P
V
-
P
V
V
L
A
A
-
S
I
E
S
T
-
N
Q
I
P
S
V
T
I
---
D
Y
E
Q
A
A
F
D
A
V
Q
S
L
I
D
S
G
H
K
N
I
A
F
V
S
G
T
L
E
E
P
I
-
N
H
A
K
K
V
K
G
Y
K
R
A
L
T
E
S
G
L
P
V
R
D
S
Y
I
V
E
G
D
Y
T
----
Y
-
D
S
G
I
E
A
V
E
K
L
L
E
E
D
E
K
P
-
T
A
I
F
-
V
G
T
D
E
-
M
A
L
G
V
I
H
G
A
Q
D
R
G
L
N
V
P
N
D
L
E
I
I
G
F
D
N
T
R
L
S
T
-
M
V
R
P
Q
L
T
S
V
V
Q
P
-
M
Y
D
I
G
-
A
V
A
M
-
R
L
L
T
K
Y
-
M
N
K
E
-
T
V
D
S
S
I
V
Q
L
P
H
R
I
E
F
R
Q
S
T
K
2
PsiBlast_PDB
93.33
27%
-76
- C3 -
1ZVV
4
CCPA_BACSU
A:
[3-331]
----
V
T
I
Y
D
V
A
R
E
A
S
V
S
M
A
T
V
S
R
V
V
N
G
N
-
P
N
V
K
P
S
T
R
K
K
V
L
E
T
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
K
K
T
T
T
V
G
V
I
I
P
D
I
S
N
I
F
Y
A
E
L
A
R
G
I
E
D
I
A
S
-
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
Q
D
K
Q
L
H
L
L
N
N
M
-
L
G
K
Q
V
D
G
I
I
F
-
M
S
G
N
V
T
E
E
H
V
E
E
L
K
-
K
S
P
V
-
P
V
V
L
A
A
-
S
I
E
S
T
-
N
Q
I
P
S
V
T
I
---
D
Y
E
Q
A
A
F
D
A
V
Q
S
L
I
D
S
G
H
K
N
I
A
F
V
S
G
T
L
E
E
P
I
-
N
H
A
K
K
V
K
G
Y
K
R
A
L
T
E
S
G
L
P
V
R
D
S
Y
I
V
E
G
D
Y
T
----
Y
-
D
S
G
I
E
A
V
E
K
L
L
E
E
D
E
K
P
-
T
A
I
F
-
V
G
T
D
E
-
M
A
L
G
V
I
H
G
A
Q
D
R
G
L
N
V
P
N
D
L
E
I
I
G
F
D
N
T
R
L
S
T
-
M
V
R
P
Q
L
T
S
V
V
Q
P
-
M
Y
D
I
G
-
A
V
A
M
-
R
L
L
T
K
Y
-
M
N
K
E
-
T
V
D
S
S
I
V
E
L
P
H
R
I
E
F
R
Q
S
T
K
11
PsiBlast_PDB
92.28
26%
-84
- C3 -
1JH9
4
PURR_ECOLI
A:
[2-308]
-----
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
-
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
-
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
-
A
Q
K
R
V
D
G
L
L
V
-
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
-
E
Y
R
H
I
P
M
V
V
M
D
-
R
G
--
E
-
A
K
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
-
R
N
-
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
----
P
-
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
-
T
A
V
F
-
C
G
G
D
I
-
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
-
Y
F
T
P
A
L
T
T
I
H
Q
P
-
K
D
S
L
G
E
T
A
F
N
-
M
L
L
D
R
I
-
V
N
K
R
-
E
E
P
Q
S
I
E
-
V
H
P
R
L
I
E
R
R
S
V
A
10
PsiBlast_PDB
91.51
26%
-85
- C3 -
1JFT
3
PURR_ECOLI
A:
[2-308]
-----
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
-
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
-
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
-
A
Q
K
R
V
D
G
L
L
V
-
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
-
E
Y
R
H
I
P
M
V
V
M
D
-
A
G
--
E
-
A
K
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
-
R
N
-
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
----
P
-
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
-
T
A
V
F
-
C
G
G
D
I
-
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
-
Y
F
T
P
A
L
T
T
I
H
Q
P
-
K
D
S
L
G
E
T
A
F
N
-
M
L
L
D
R
I
-
V
N
K
R
-
E
E
P
Q
S
I
E
-
V
H
P
R
L
I
E
R
R
S
V
A
57
Fugue
90.77
25%
-85
- C3 -
1RZR
5
CCPA_BACME
A:
[2-332]
---
N
V
T
I
Y
D
V
A
R
E
A
S
V
S
M
A
T
V
S
R
V
V
N
G
N
-
P
N
V
K
P
S
T
R
K
K
V
L
E
T
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
K
K
T
T
T
V
G
V
I
I
P
D
I
S
N
I
F
Y
A
E
L
A
R
G
I
E
D
I
A
T
M
Y
-
K
Y
N
I
I
L
S
N
S
D
Q
N
Q
D
K
E
L
H
L
L
N
-
N
M
L
G
K
Q
V
D
G
I
I
F
M
S
G
N
V
T
-
E
E
H
V
E
E
L
K
-
K
S
P
V
-
P
V
V
L
A
A
-
S
I
E
S
T
-
N
Q
I
P
S
V
T
I
---
D
Y
E
Q
A
A
F
D
A
V
Q
S
L
I
D
S
G
H
K
N
I
A
F
V
S
G
T
L
E
E
P
I
-
N
H
A
K
K
V
K
G
Y
K
R
A
L
T
E
S
G
L
P
V
-
R
D
S
Y
I
V
E
G
D
Y
----
T
-
Y
D
S
G
I
E
A
V
E
K
L
L
E
E
D
E
K
P
T
A
I
F
-
V
G
T
D
E
M
A
L
-
G
V
I
H
G
A
Q
D
R
G
L
N
V
P
N
D
L
E
I
I
G
F
D
N
T
R
L
S
T
M
V
R
-
P
Q
L
T
S
V
V
Q
P
M
Y
---
D
I
G
A
V
A
M
R
L
L
T
K
Y
M
N
K
E
T
-
V
D
S
S
I
V
Q
-
L
P
H
R
I
E
F
R
Q
S
T
K
5
PsiBlast_PDB
90.73
27%
-79
- C3 -
3OQN
2
CCPA_BACSU
A:
[3-321]
----
I
T
I
Y
D
V
A
R
E
A
N
V
S
M
A
T
V
S
R
V
V
N
G
N
-
P
N
V
K
P
T
T
R
K
K
V
L
E
A
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
K
K
T
T
T
V
G
V
I
I
P
D
I
S
S
I
F
Y
S
E
L
A
R
G
I
E
D
I
A
T
-
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
M
E
K
E
L
H
L
L
N
T
M
-
L
G
K
Q
V
D
G
I
V
F
-
M
G
G
N
I
T
D
E
H
V
A
E
F
K
-
R
S
P
V
-
P
I
V
L
A
A
-
S
V
E
E
Q
-
E
E
T
P
S
V
A
I
---
D
Y
E
Q
A
I
Y
D
A
V
K
L
L
V
D
K
G
H
T
D
I
A
F
V
S
G
P
M
A
E
P
I
-
N
R
S
K
K
L
Q
G
Y
K
R
A
L
E
E
A
N
L
P
F
-
N
E
Q
F
V
A
E
G
D
Y
----
T
Y
D
S
G
L
E
A
L
Q
H
L
M
S
L
D
K
K
P
-
T
A
I
L
S
A
T
D
E
M
-
A
L
G
I
I
H
A
A
-
Q
D
Q
G
L
S
I
P
E
D
L
D
I
I
G
F
D
N
T
R
L
S
L
-
M
V
R
P
Q
L
S
T
V
V
Q
P
-
T
Y
D
I
G
-
A
V
A
M
-
R
L
L
T
K
L
-
M
N
K
E
-
P
V
E
-
E
H
I
-
V
E
L
P
H
R
I
E
L
R
K
S
17
PsiBlast_PDB
90.64
26%
-83
- C3 -
1PNR
2
PURR_ECOLI
A:
[2-308]
-----
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
-
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
-
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
-
A
Q
K
R
V
D
G
L
L
V
-
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
-
E
Y
R
H
I
P
M
V
V
M
D
W
G
E
A
K
A
-
D
F
T
D
A
V
I
D
---
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
-
R
N
-
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
----
P
-
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
-
T
A
V
F
-
C
G
G
D
I
-
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
-
Y
F
T
P
A
L
T
T
I
H
Q
P
-
K
D
S
L
G
E
T
A
F
N
-
M
L
L
D
R
I
-
V
N
K
R
-
E
E
P
Q
S
I
E
-
V
H
P
R
L
I
E
R
R
S
V
A
4
PsiBlast_PDB
90.29
27%
-71
- C3 -
3OQM
4
CCPA_BACSU
A:
[3-321]
----
I
T
I
Y
D
V
A
R
E
A
N
V
S
M
A
T
V
S
R
V
V
N
G
N
-
P
N
V
K
P
T
T
R
K
K
V
L
E
A
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
K
K
T
T
T
V
G
V
I
I
P
D
I
S
S
I
F
Y
S
E
L
A
R
G
I
E
D
I
A
T
-
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
M
E
K
E
L
H
L
L
N
T
M
-
L
G
K
Q
V
D
G
I
V
F
-
M
G
G
N
I
T
D
E
H
V
A
E
F
K
-
R
S
P
V
-
P
I
V
L
A
A
-
S
V
E
E
Q
-
E
E
T
P
S
V
A
I
---
D
Y
E
Q
A
I
Y
D
A
V
K
L
L
V
D
K
G
H
T
D
I
A
F
V
S
G
P
M
A
E
P
I
-
N
R
S
K
K
L
Q
G
Y
K
R
A
L
E
E
A
N
L
P
F
-
N
E
Q
F
V
A
E
G
D
Y
----
T
Y
D
S
G
L
E
A
L
Q
H
L
M
S
L
D
K
K
P
-
T
A
I
L
S
A
T
D
E
M
-
A
L
G
I
I
H
A
A
-
Q
D
Q
G
L
S
I
P
E
D
L
D
I
I
G
F
D
N
T
R
L
S
L
-
M
V
R
P
Q
L
S
T
V
V
Q
P
-
T
Y
D
I
G
-
A
V
A
M
-
R
L
L
T
K
L
-
M
N
K
E
-
P
V
E
-
E
H
I
-
V
E
L
P
H
R
I
E
L
R
K
S
15
PsiBlast_PDB
90.26
26%
-85
- C3 -
2PUC
2
PURR_ECOLI
A:
[2-308]
-----
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
-
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
-
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
-
A
Q
K
R
V
D
G
L
L
V
-
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
-
E
Y
R
H
I
P
M
V
V
M
D
W
G
E
A
K
A
-
D
F
T
D
A
V
I
D
---
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
-
A
N
-
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
----
P
-
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
-
T
A
V
F
-
C
G
G
D
I
-
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
-
Y
F
T
P
A
L
T
T
I
H
Q
P
-
K
D
S
L
G
E
T
A
F
N
-
M
L
L
D
R
I
-
V
N
K
R
-
E
E
P
Q
S
I
E
-
V
H
P
R
L
I
E
R
R
S
V
A
13
PsiBlast_PDB
90.22
26%
-82
- C3 -
2PUA
2
PURR_ECOLI
A:
[2-308]
-----
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
-
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
-
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
-
A
Q
K
R
V
D
G
L
L
V
-
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
-
E
Y
R
H
I
P
M
V
V
M
D
W
G
E
A
K
A
-
D
F
T
D
A
V
I
D
---
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
-
A
N
-
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
----
P
-
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
-
T
A
V
F
-
C
G
G
D
I
-
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
-
Y
F
T
P
A
L
T
T
I
H
Q
P
-
K
D
S
L
G
E
T
A
F
N
-
M
L
L
D
R
I
-
V
N
K
R
-
E
E
P
Q
S
I
E
-
V
H
P
R
L
I
E
R
R
S
V
A
19
PsiBlast_PDB
90.14
26%
-83
- C3 -
1WET
2
PURR_ECOLI
A:
[2-308]
-----
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
-
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
-
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
-
A
Q
K
R
V
D
G
L
L
V
-
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
-
E
Y
R
H
I
P
M
V
V
M
D
W
G
E
A
K
A
-
D
F
T
D
A
V
I
D
---
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
-
R
N
-
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
----
P
-
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
-
T
A
V
F
-
C
G
G
D
I
-
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
-
Y
F
T
P
A
L
T
T
I
H
Q
P
-
K
D
S
L
G
E
T
A
F
N
-
M
L
L
D
R
I
-
V
N
K
R
-
E
E
P
Q
S
I
E
-
V
H
P
R
L
I
E
R
R
S
V
A
12
PsiBlast_PDB
90.14
26%
-87
- C3 -
1JFS
2
PURR_ECOLI
A:
[2-308]
-----
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
-
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
-
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
-
A
Q
K
R
V
D
G
L
L
V
-
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
-
E
Y
R
H
I
P
M
V
V
M
D
---
F
G
E
-
A
K
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
-
R
N
-
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
----
P
-
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
-
T
A
V
F
-
C
G
G
D
I
-
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
-
Y
F
T
P
A
L
T
T
I
H
Q
P
-
K
D
S
L
G
E
T
A
F
N
-
M
L
L
D
R
I
-
V
N
K
R
-
E
E
P
Q
S
I
E
-
V
H
P
R
L
I
E
R
R
S
V
A
16
PsiBlast_PDB
90.00
26%
-86
- C3 -
2PUD
2
PURR_ECOLI
A:
[2-308]
-----
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
-
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
-
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
-
A
Q
K
R
V
D
G
L
L
V
-
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
-
E
Y
R
H
I
P
M
V
V
M
D
W
G
E
A
K
A
-
D
F
T
D
A
V
I
D
---
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
-
A
N
-
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
----
P
-
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
-
T
A
V
F
-
C
G
G
D
I
-
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
-
Y
F
T
P
A
L
T
T
I
H
Q
P
-
K
D
S
L
G
E
T
A
F
N
-
M
L
L
D
R
I
-
V
N
K
R
-
E
E
P
Q
S
I
E
-
V
H
P
R
L
I
E
R
R
S
V
A
18
PsiBlast_PDB
89.98
26%
-85
- C3 -
1BDI
2
PURR_ECOLI
A:
[2-308]
-----
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
-
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
-
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
-
A
Q
K
R
V
D
G
L
L
V
-
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
-
E
Y
R
H
I
P
M
V
V
M
D
W
G
E
A
K
A
-
D
F
T
D
A
V
I
D
---
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
-
R
N
-
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
----
P
-
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
-
T
A
V
F
-
C
G
G
D
I
-
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
-
Y
F
T
P
A
L
T
T
I
H
Q
P
-
K
D
S
L
G
E
T
A
F
N
-
M
L
L
D
R
I
-
V
N
K
R
-
E
E
P
Q
S
I
E
-
V
H
P
R
L
I
E
R
R
S
V
A
20
PsiBlast_PDB
89.92
26%
-84
- C3 -
1QP0
2
PURR_ECOLI
A:
[2-308]
-----
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
-
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
-
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
-
A
Q
K
R
V
D
G
L
L
V
-
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
-
E
Y
R
H
I
P
M
V
V
M
D
W
G
E
A
K
A
-
D
F
T
D
A
V
I
D
---
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
-
R
N
-
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
----
P
-
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
-
T
A
V
F
-
C
G
G
D
I
-
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
-
Y
F
T
P
A
L
T
T
I
H
Q
P
-
K
D
S
L
G
E
T
A
F
N
-
M
L
L
D
R
I
-
V
N
K
R
-
E
E
P
Q
S
I
E
-
V
H
P
R
L
I
E
R
R
S
V
A
14
PsiBlast_PDB
89.90
26%
-86
- C3 -
2PUB
2
PURR_ECOLI
A:
[2-308]
-----
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
-
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
-
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
-
A
Q
K
R
V
D
G
L
L
V
-
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
-
E
Y
R
H
I
P
M
V
V
M
D
W
G
E
A
K
A
-
D
F
T
D
A
V
I
D
---
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
-
A
N
-
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
S
W
I
V
Q
G
D
F
E
----
P
-
E
S
G
Y
R
A
M
Q
Q
I
L
S
Q
P
H
R
P
-
T
A
V
F
-
C
G
G
D
I
-
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
-
Y
F
T
P
A
L
T
T
I
H
Q
P
-
K
D
S
L
G
E
T
A
F
N
-
M
L
L
D
R
I
-
V
N
K
R
-
E
E
P
Q
S
I
E
-
V
H
P
R
L
I
E
R
R
S
V
A
1
PsiBlast_PDB
89.81
27%
-68
- C3 -
2HSG
-
CCPA_BACME
A:
[3-331]
----
V
T
I
Y
D
V
A
R
E
A
S
V
S
M
A
T
V
S
R
V
V
N
G
N
-
P
N
V
K
P
S
T
R
K
K
V
L
E
T
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
-
K
T
T
T
V
G
V
I
I
P
--
S
N
I
F
Y
A
E
L
A
R
G
I
E
D
I
A
T
-
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
Q
D
K
E
L
H
L
L
N
N
M
-
L
G
K
Q
V
D
G
I
I
F
-
M
S
G
N
V
T
E
E
H
V
E
E
L
K
-
K
S
P
V
-
P
V
V
L
A
A
-
S
I
E
S
T
-
N
Q
I
P
S
V
T
I
---
D
Y
E
Q
A
A
F
D
A
V
Q
S
L
I
D
S
G
H
K
N
I
A
F
V
S
G
T
L
E
E
P
I
-
N
H
A
K
K
V
K
G
Y
K
R
A
L
T
E
S
G
L
P
V
R
D
S
Y
I
V
E
G
D
Y
T
----
Y
-
D
S
G
I
E
A
V
E
K
L
L
E
E
D
E
K
P
-
T
A
I
F
-
V
G
T
D
E
-
M
A
L
G
V
I
H
G
A
Q
D
R
G
L
N
V
P
N
D
L
E
I
I
G
F
D
N
T
R
L
S
T
-
M
V
R
P
Q
L
T
S
V
V
Q
P
-
M
Y
D
I
G
-
A
V
A
M
-
R
L
L
T
K
Y
-
M
N
K
E
-
T
V
D
S
S
I
V
Q
L
P
H
R
I
E
F
R
Q
S
T
K
42
HHSearch
89.58
26%
-70
- C3 -
1QPZ
2
PURR_ECOLI
A:
[1-330]
----
A
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
R
F
-
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
-
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
-
A
Q
K
R
V
D
G
L
L
V
-
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
E
Y
R
H
I
-
P
M
V
V
M
D
-
W
G
E
A
K
A
D
F
T
D
A
V
I
D
---
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
L
E
-
R
N
-
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
-
P
E
S
W
I
V
Q
G
D
F
E
P
E
S
G
-
Y
R
A
M
Q
Q
I
L
S
Q
---
P
H
R
P
-
T
A
V
F
-
C
G
G
D
I
-
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
-
Y
F
T
P
A
L
T
T
I
H
Q
P
-
K
D
S
L
G
E
T
A
F
N
-
M
L
L
D
R
I
-
V
N
K
R
E
E
-
P
Q
S
I
E
-
V
H
P
R
L
I
E
R
R
S
V
A
6
PsiBlast_PDB
89.47
27%
-76
- C3 -
3OQO
4
CCPA_BACSU
A:
[3-321]
----
I
T
I
Y
D
V
A
R
E
A
N
V
S
M
A
T
V
S
R
V
V
N
G
N
-
P
N
V
K
P
T
T
R
K
K
V
L
E
A
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
K
K
T
T
T
V
G
V
I
I
P
D
I
S
S
I
F
Y
S
E
L
A
R
G
I
E
D
I
A
T
-
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
M
E
K
E
L
H
L
L
N
T
M
-
L
G
K
Q
V
D
G
I
V
F
-
M
G
G
N
I
T
D
E
H
V
A
E
F
K
-
R
S
P
V
-
P
I
V
L
A
A
-
S
V
E
E
Q
-
E
E
T
P
S
V
A
I
---
D
Y
E
Q
A
I
Y
D
A
V
K
L
L
V
D
K
G
H
T
D
I
A
F
V
S
G
P
M
A
E
P
I
-
N
R
S
K
K
L
Q
G
Y
K
R
A
L
E
E
A
N
L
P
F
-
N
E
Q
F
V
A
E
G
D
Y
----
T
Y
D
S
G
L
E
A
L
Q
H
L
M
S
L
D
K
K
P
-
T
A
I
L
S
A
T
D
E
M
-
A
L
G
I
I
H
A
A
-
Q
D
Q
G
L
S
I
P
E
D
L
D
I
I
G
F
D
N
T
R
L
S
L
-
M
V
R
P
Q
L
S
T
V
V
Q
P
-
T
Y
D
I
G
-
A
V
A
M
-
R
L
L
T
K
L
-
M
N
K
E
-
P
V
E
-
E
H
I
-
V
E
L
P
H
R
I
E
L
R
K
S
35
HHSearch
85.63
26%
-65
- C3 -
2HSG
-
CCPA_BACME
A:
[2-332]
---
N
V
T
I
Y
D
V
A
R
E
A
S
V
S
M
A
T
V
S
R
V
V
N
G
N
P
N
-
V
K
P
S
T
R
K
K
V
L
E
T
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
-
K
T
T
T
V
G
V
I
I
P
--
S
N
I
F
Y
A
E
L
A
R
G
I
E
D
I
A
T
-
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
Q
D
K
E
L
H
L
L
N
N
M
-
L
G
K
Q
V
D
G
I
I
F
-
M
S
G
N
V
T
E
E
H
V
E
E
L
K
-
K
S
P
V
-
P
V
V
L
A
A
-
S
I
E
S
T
-
N
Q
I
P
S
V
T
I
---
D
Y
E
Q
A
A
F
D
A
V
Q
S
L
I
D
S
G
H
K
N
I
A
F
V
S
G
T
L
E
-
E
P
I
N
H
A
K
K
V
K
G
Y
K
R
A
L
T
E
S
G
L
P
V
-
R
D
S
Y
I
V
E
G
D
Y
T
Y
D
S
G
-
I
E
A
V
E
K
L
L
E
E
---
D
E
K
P
-
T
A
I
F
-
V
G
T
D
E
-
M
A
L
G
V
I
H
G
A
Q
D
R
G
L
N
V
P
N
D
L
E
I
I
G
F
D
N
T
R
L
S
T
-
M
V
R
P
Q
L
T
S
V
V
Q
P
-
M
Y
D
I
G
A
V
A
M
R
-
L
L
T
K
Y
M
-
N
K
E
T
V
D
-
S
S
I
V
Q
-
L
P
H
R
I
E
F
R
Q
S
T
K