@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1991: (2015-12-12 )
MEIKEYENNPYHLAQLVDLINYCQNIEAKLDIKMAEQDDIFQIENYYQNRKGQFWIALENEKVVGSIALLRIDDKTAVLKKFFTYPKYRGNPVRLGRKLFERFMLFARASKFTRIVLDTPEKEKRSHFFYENQGFKQITRDELDVDYIFPDRDSRIYVKLLD
Atome Classification :
(20 SA)
---.........10........20........30---..---....-------..40..---......50...-.....60.........70-.----.-------------.----..------...80........90...--.....100.......110.......--.120.......130.......140------.....-..150.......160---------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---ME
I
K
EYENN
P
Y
H
L
A
Q
L
V
D
L
I
N
Y
C
Q
NI
E
A
K
L
D
---
I
K
---MAEQ-------DD
I
F
Q
I
---
E
N
Y
Y
QNRKG
Q
F
-
W
I
A
LEN-E
K
V
V
G
S
I
A
L
L
R
-I----D-------------
D
----
K
T
------
A
V
L
K
K
F
FTYPKYRG
N
P
V
R
--
L
G
R
K
L
F
E
R
F
M
L
F
A
R
AS
K
-
F
T
R
I
V
L
D--TP
E
K
E
K
R
SH
F
F
YENQ
G
F
K
Q
I
T
RDE------LD
V
D
Y
-IFPDRD
S
R
I
Y
V
K
LLD---------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
93.49
99%
-124
- C1 -
2Q7B
2
?
A:
[21-180]
----
E
I
K
E
Y
E
N
N
P
Y
H
L
A
Q
L
V
D
L
I
N
Y
C
Q
N
I
E
A
K
L
D
---
I
K
---
M
A
E
Q
-------
D
D
I
F
Q
I
---
E
N
Y
Y
Q
N
R
K
G
Q
F
-
W
I
A
L
E
N
-
E
K
V
V
G
S
I
A
L
L
R
-
I
----
D
-------------
D
----
K
T
------
A
V
L
K
K
F
F
T
Y
P
K
Y
R
G
N
--
P
VR
L
G
R
K
L
F
E
R
F
M
L
F
A
R
A
S
K
-
F
T
R
I
V
L
D
--
T
P
E
K
E
K
R
S
H
F
F
Y
E
N
Q
G
F
K
Q
I
T
R
D
E
------
L
D
V
D
Y
-
I
F
P
D
R
D
S
R
I
Y
V
K
L
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
93.46
98%
-121
- C1 -
2Q7B
2
?
A:
[21-180]
----
E
I
K
E
Y
E
N
N
P
Y
H
L
A
Q
L
V
D
L
I
N
Y
C
Q
N
I
E
A
K
L
D
---
I
K
---
M
A
E
Q
-------
D
D
I
F
Q
I
---
E
N
Y
Y
Q
N
R
K
G
Q
F
-
W
I
A
L
E
N
-
E
K
V
V
G
S
I
A
L
L
R
-
I
----
D
-------------
D
----
K
T
------
A
V
L
K
K
F
F
T
Y
P
K
Y
R
G
N
P
V
R
--
L
G
R
K
L
F
E
R
F
M
L
F
A
R
A
S
K
-
F
T
R
I
V
L
D
--
T
P
E
K
E
K
R
S
H
F
F
Y
E
N
Q
G
F
K
Q
I
T
R
D
E
------
L
D
V
D
Y
-
I
F
P
D
R
D
S
R
I
Y
V
K
L
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
59.62
33%
-91
- C1 -
3D8P
6
?
A:
[3-161]
----
A
I
N
I
I
E
Y
N
R
S
Y
K
E
E
L
I
E
F
I
L
S
I
Q
K
N
E
F
N
I
K
---
I
D
---
R
D
D
Q
-------
P
D
L
E
N
I
---
E
H
N
Y
L
N
S
G
G
Q
F
-
W
L
A
I
N
N
H
Q
N
I
V
G
T
I
G
L
I
R
-
L
----
D
-------------
N
----
N
M
------
S
A
L
K
K
M
F
V
D
K
G
Y
R
N
L
--
K
--
I
G
K
K
L
L
D
K
V
I
M
T
C
K
E
Q
N
-
I
D
G
I
Y
L
G
--
T
I
D
K
F
I
S
A
Q
Y
F
Y
S
N
N
G
F
R
E
I
K
R
G
D
------
L
P
S
S
F
-
P
K
L
--
D
N
R
F
Y
Y
R
N
L
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
57.95
32%
-97
- C1 -
3D8P
6
?
A:
[8-161]
---------
E
Y
N
R
S
Y
K
E
E
L
I
E
F
I
L
S
I
Q
K
N
E
F
N
I
K
---
I
D
---
R
D
D
Q
-------
P
D
L
E
N
I
---
E
H
N
Y
L
N
S
G
G
Q
F
-
W
L
A
I
N
N
H
Q
N
I
V
G
T
I
G
L
I
R
-
L
----
D
-------------
N
----
N
M
------
S
A
L
K
K
M
F
V
D
K
G
Y
R
N
--
L
K
--
I
G
K
K
L
L
D
K
V
I
M
T
C
K
E
Q
N
-
I
D
G
I
Y
L
G
--
T
I
D
K
F
I
S
A
Q
Y
F
Y
S
N
N
G
F
R
E
I
K
R
G
D
------
L
P
S
S
F
-
P
K
L
--
D
N
R
F
Y
Y
R
N
L
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
51.99
22%
-94
- C1 -
2DXQ
5
?
A:
[5-144]
----
A
I
S
L
R
A
A
G
P
G
D
L
P
G
L
L
E
L
Y
Q
V
L
N
P
S
D
P
E
------
L
---
T
T
-
Q
-------
E
A
G
A
V
F
---
A
A
M
L
A
Q
P
G
L
T
I
-
F
V
A
T
E
N
-
G
K
P
V
A
T
A
T
L
L
I
-
V
----
P
N
LTRAA-------
R
----
P
Y
------
A
F
I
E
N
V
V
T
L
E
A
R
R
G
R
--
G
--
Y
G
R
T
V
V
R
H
A
I
E
T
A
F
G
A
N
-
C
Y
K
V
M
L
L
--
T
G
R
H
D
P
A
V
H
A
F
Y
E
S
C
G
F
V
Q
N
K
T
G
F
------
Q
I
R
Q
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
51.67
26%
-148
- C1 -
2DXQ
4
?
A:
[53-140]
------------------------------------------------------------------------
I
-
F
V
A
T
E
N
-
G
K
P
V
A
T
A
T
L
L
I
-
V
----
P
-------------
N
----
L
T
RAA
R
P
Y
A
F
I
E
N
V
V
T
L
E
A
R
R
G
R
--
G
--
Y
G
R
T
V
V
R
H
A
I
E
T
A
F
G
A
N
-
C
Y
K
V
M
L
L
--
T
G
R
H
D
P
A
V
H
A
F
Y
E
S
C
G
F
V
Q
N
K
T
G
F
------
Q
I
R
Q
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
49.79
26%
-142
- C1 -
3PP9
3
?
A:
[66-157]
----------------------------------------------------------
V
---
Y
N
E
Y
I
N
K
P
N
Q
I
I
Y
I
A
L
L
H
-
N
Q
I
I
G
F
I
V
L
K
K
-
N
----
W
-------------
N
----
N
Y
------
A
Y
I
E
D
I
T
V
D
K
K
Y
R
--
T
L
G
--
V
G
K
R
L
I
A
Q
A
K
Q
W
A
K
E
G
N
-
M
P
G
I
M
L
E
--
T
Q
N
N
N
V
A
A
C
K
F
Y
E
K
C
G
F
V
I
G
G
F
D
F
------
L
V
Y
K
G
-
L
N
M
T
S
D
E
V
A
I
Y
W
Y
L
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
48.60
16%
-86
- C1 -
3H4Q
2
?
A:
[19-186]
-----
G
M
I
R
L
G
K
M
S
D
L
D
Q
I
L
N
L
V
E
E
A
K
E
L
M
K
--------------
Y
-------
P
L
L
E
H
F
---
E
E
D
I
A
--
K
D
Y
L
-
Y
V
L
E
E
N
-
D
K
I
Y
G
F
I
V
V
D
Q
-
D
----
Q
AEWYDDIDWPVNR
E
----
G
A
------
F
V
I
H
R
L
T
G
S
K
E
Y
--
K
--
G
--
A
A
T
E
L
F
N
Y
V
I
D
V
V
K
A
R
G
-
A
E
V
I
L
T
D
--
T
F
A
L
N
K
P
A
Q
G
L
F
A
K
F
G
F
H
K
V
---------------------
P
F
Y
A
Y
Y
K
N
L
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
48.13
13%
-74
- C1 -
2AE6
1
?
A:
[7-163]
----
S
L
T
I
R
L
V
A
E
A
D
W
P
A
L
H
A
L
D
Q
I
I
----------------------------
S
L
A
A
Y
---
Q
E
K
M
K
--
D
E
T
I
-
F
V
A
I
S
G
-
Q
Q
L
A
G
F
I
E
V
H
P
-
P
----
T
SLAA---------
H
----
Q
K
------
Q
W
L
L
S
I
G
V
S
P
D
F
Q
D
Q
--
G
--
I
G
G
S
L
L
S
Y
I
K
D
M
A
E
I
S
G
-
I
H
K
L
S
L
R
--
V
M
A
T
N
Q
E
A
I
R
F
Y
E
K
H
G
F
V
Q
E
A
H
F
K
------
E
E
F
Y
I
-
N
G
H
Y
C
D
D
Y
Q
Y
A
Y
F
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
48.03
19%
-78
- C1 -
1TIQ
4
PAIA_BACSU
A:
[2-170]
----
S
V
K
M
K
K
C
S
R
E
D
L
Q
T
L
Q
Q
L
S
I
E
T
F
N
D
T
F
K
E
Q
---
N
S
---
P
E
N
M
K
A
Y
L
E
S
A
F
N
T
E
Q
L
---
E
K
E
L
S
N
M
S
S
Q
F
-
F
F
I
Y
F
D
-
H
E
I
A
G
Y
V
K
V
N
I
-
D
----
D
AQSEEMG------
A
----
E
S
------
L
E
I
E
R
I
Y
I
K
N
S
F
Q
K
H
--
G
--
L
G
K
H
L
L
N
K
A
I
E
I
A
L
E
R
N
-
K
K
N
I
W
L
G
--
V
W
E
K
N
E
N
A
I
A
F
Y
K
K
M
G
F
V
Q
T
G
A
H
S
------
F
Y
M
---
G
D
E
E
Q
T
D
L
I
M
A
K
T
L
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
46.49
17%
-73
- C1 -
1MK4
-
YQJY_BACSU
A:
[1-156]
-----
M
D
I
R
T
I
T
S
S
D
Y
E
M
V
T
S
V
L
N
E
W
W
G
G
R
Q
-------
L
---
K
E
K
L
-------
P
--
R
L
F
---
F
E
H
F
Q
---
D
T
S
-
F
I
T
S
E
H
-
N
S
M
T
G
F
L
I
G
F
Q
-
S
QS--
D
-------------
P
----
E
T
------
A
Y
I
H
F
S
G
V
H
P
D
F
R
K
M
--
Q
--
I
G
K
Q
L
Y
D
V
F
I
E
T
V
K
Q
R
G
-
C
T
R
V
K
C
V
--
T
S
P
V
N
K
V
S
I
A
Y
H
T
K
L
G
F
D
I
E
K
G
T
K
TVNG
I
S
V
F
A
N
Y
-
D
G
P
G
Q
D
R
V
L
F
V
K
N
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
46.01
18%
-75
- C1 -
2FIA
-
?
A:
[1-157]
---
M
K
I
R
V
A
--
D
E
K
E
L
P
M
I
L
Q
F
L
T
E
V
K
A
Y
M
D
V
V
G
---
I
T
---
Q
W
T
K
-------
D
Y
P
S
Q
G
---
D
I
Q
E
D
I
T
K
K
R
L
-
Y
L
L
V
H
E
-
E
M
I
F
S
M
A
T
F
C
M
-
E
Q---
E
-------------
Q
----
D
F
------
V
W
L
K
R
F
A
T
S
P
N
Y
I
A
K
--
G
--
Y
G
S
L
L
F
H
E
L
E
K
R
A
V
W
E
G
-
R
R
K
M
Y
A
Q
--
T
N
H
T
N
H
R
M
I
R
F
F
E
S
K
G
F
T
K
I
H
E
S
L
------
Q
M
--
N
-
R
L
D
F
G
S
F
Y
L
Y
V
K
E
L
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
46.00
17%
-73
- C1 -
2OB0
1
NAA50_HUMAN
A:
[6-155]
----
R
I
E
L
G
D
V
T
P
H
N
I
K
Q
L
K
R
L
N
Q
V
I
F
P
V
S
Y
N
D
-----------------------
K
F
Y
---
K
D
V
L
E
-
V
G
E
L
A
-
K
L
A
Y
F
N
-
D
I
A
V
G
A
V
C
C
R
V
-
D
----
H
SQN----------
Q
----
K
R
------
L
Y
I
M
T
L
G
C
L
A
P
Y
R
R
L
--
G
--
I
G
T
K
M
L
N
H
V
L
N
I
C
E
K
D
G
T
F
D
N
I
Y
L
H
--
V
Q
I
S
N
E
S
A
I
D
F
Y
R
K
F
G
F
E
I
I
E
T
K
K
------
N
Y
Y
K
--
R
I
E
P
A
D
A
H
V
L
Q
K
N
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
45.92
12%
-54
- C1 -
2WPX
2
?
A:
[5-338]
A
G
E
L
E
F
V
P
L
A
A
N
D
D
E
T
V
G
Q
W
L
D
L
M
A
L
A
A
E
T
G
P
R
A
---
A
P
---
P
C
N
V
-------
D
M
V
G
S
L
---
R
F
A
P
P
A
T
A
L
D
D
-
W
V
V
R
S
G
-
G
R
V
V
G
A
L
R
L
A
L
P
D
----
G
-------------
A
----
P
T
------
A
R
V
D
Q
L
L
V
H
P
G
R
R
R
R
--
G
--
I
G
R
A
L
W
A
H
A
R
E
L
A
R
K
H
D
-
R
T
T
L
T
A
T
--
V
V
E
S
L
P
S
G
P
---
A
Q
D
P
G
P
A
A
F
A
A
A
------
M
G
A
H
R
-
S
D
I
P
A
G
T
H
Q
W
L
D
L
D
R
HDPLADGVPAVPAG
Y
S
L
V
T
W
G
TITPDEY
A
V
P
V
S
E
LELRAAQE
V
R
T
S
Y
A
R
Q
F
E
T
M
R
V
G
R
G
R
R
A
Y
H
T
G
A
V
HDATGALA
G
Y
T
S
V
S
K
T
TGNPA
Y
A
L
Q
G
M
T
V
V
H
REHRGHA
L
G
T
L
L
K
L
A
N
L
E
Y
V
L
R
H
E
PEVR
L
V
E
T
A
N
AEDN
H
P
M
I
A
V
N
A
A
L
G
F
E
P
Y
D
R
W
V
F
W
T
A
E
AGPS
18
HHSearch
44.38
15%
-90
- C1 -
3JVN
1
?
A:
[3-136]
-----
P
V
I
R
R
A
K
E
I
D
L
Y
C
L
N
S
L
M
Y
K
L
H
D
E
H
H
Q
Q
C
---
P
D
----------------
E
K
S
I
---
A
R
Y
L
D
D
P
E
C
M
V
-
Y
V
A
E
M
D
-
D
V
I
I
G
F
I
T
G
H
F
-
C
----
E
LISTVS
K
L
-----
V
----
M
M
------
A
T
I
D
E
L
Y
I
E
K
E
Y
R
R
E
--
G
--
V
A
E
Q
L
M
M
R
I
E
Q
E
L
K
D
Y
G
-
V
K
E
I
F
V
E
--
V
W
--
N
K
G
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
43.54
17%
-57
- C1 -
3DR6
3
MDDA_SALTY
A:
[3-165]
----
A
M
T
I
R
F
A
D
K
A
D
C
A
A
I
T
E
I
Y
N
H
A
V
L
H
T
A
A
I
W
---
N
D
R
T
-
V
D
T
D
-------
N
R
L
A
W
Y
---
E
A
-
R
Q
L
L
G
Y
P
V
-
L
V
S
E
E
N
-
G
V
V
T
G
Y
A
S
F
G
D
-
W
----
R
SFDG---------
F
----
R
Y
------
T
V
E
H
S
V
Y
V
H
P
A
H
Q
G
K
--
G
--
L
G
R
K
L
L
S
R
L
I
D
E
A
R
R
C
G
-
K
H
V
M
V
A
G
--
I
E
S
Q
N
A
A
S
I
R
L
H
H
S
L
G
F
T
V
T
A
Q
M
P
------
Q
V
G
V
K
-
F
G
R
W
L
D
L
T
F
M
Q
L
Q
L
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
42.98
18%
-62
- C1 -
2GE3
1
?
A:
[7-168]
----
T
V
T
I
K
P
I
R
A
E
H
V
E
S
F
H
R
A
L
D
A
V
S
R
E
R
K
Y
L
S
FL-
E
A
---
P
P
L
E
-------
A
V
R
A
F
V
---
L
D
M
I
E
N
-
D
H
P
Q
-
F
V
A
I
A
D
-
G
D
V
I
G
W
C
D
I
R
R
-
Q
----
D
-------------
R
ATR-
A
H
------
C
G
T
L
G
M
G
I
L
P
A
Y
R
N
K
--
G
--
L
G
A
R
L
M
R
R
T
L
D
A
A
H
E
F
G
-
L
H
R
I
E
L
S
--
V
H
A
D
N
A
R
A
I
A
L
Y
E
K
I
G
F
A
H
E
G
R
A
R
------
D
A
V
S
I
-
D
G
H
Y
I
D
S
L
N
M
A
I
I
F
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
42.79
17%
-87
- C1 -
1YX0
-
YSNE_BACSU
A:
[1-151]
---
M
H
I
K
I
D
D
L
T
G
R
Q
V
V
S
L
V
N
E
H
L
------
H
S
M
T
---
L
M
---
S
P
P
E
-------
S
I
H
A
L
G
---
L
E
K
L
R
G
P
E
I
T
F
-
W
S
A
W
E
G
-
D
E
L
A
G
C
G
A
L
K
E
-
L
----
D
-------------
T
----
R
H
------
G
E
I
K
S
M
R
T
S
A
S
H
L
R
K
--
G
--
V
A
K
Q
V
L
Q
H
I
I
E
E
A
E
K
R
G
-
Y
E
R
L
S
L
E
T
G
S
M
A
S
F
E
P
A
R
K
L
Y
E
S
F
G
F
Q
Y
C
E
P
F
A
----------
D
-
Y
G
E
D
P
N
S
V
F
M
T
K
K
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
42.15
17%
-64
- C1 -
1GHE
1
TTR_PSEAJ
A:
[4-173]
-----
A
Q
L
R
R
V
T
A
E
S
F
A
H
Y
R
H
G
L
A
Q
L
L
F
E
T
V
H
G
G
ASV
G
F
MAD
L
D
M
Q
-------
Q
A
Y
A
W
C
D
G
L
K
A
D
I
A
A
G
S
L
L
L
-
W
V
V
A
E
D
-
D
N
V
L
A
S
A
Q
L
S
L
-
C
----
Q
-------------
K
PNGL
N
R
------
A
E
V
Q
K
L
M
V
L
P
S
A
R
G
R
--
G
--
L
G
R
Q
L
M
D
E
V
E
Q
V
A
V
K
H
K
-
R
G
L
L
H
L
D
--
T
E
-
A
G
S
V
A
E
A
F
Y
S
A
L
A
Y
T
R
V
G
E
L
P
------
G
Y
C
A
T
P
D
G
R
L
H
P
T
A
I
Y
F
K
T
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
40.50
18%
-60
- C1 -
3LD2
2
?
A:
[34-191]
----
S
M
K
I
S
P
M
L
L
S
D
I
E
Q
V
V
E
L
E
N
K
T
W
S
E
Q
N
T
P
V
---
P
L
---
P
V
---------
A
S
K
D
Q
I
---
I
Q
K
F
E
-
S
N
T
H
F
-
L
V
A
K
I
K
-
D
K
I
V
G
V
L
D
Y
S
S
-
L
YPFP
S
-------------
G
----
Q
H
------
I
V
T
F
G
I
A
V
A
E
K
E
R
R
K
--
G
--
I
G
R
A
L
V
Q
I
F
L
N
E
V
K
S
-
D
-
Y
Q
K
V
L
I
H
--
V
L
S
S
N
Q
E
A
V
L
F
Y
K
K
L
G
F
D
L
E
A
R
L
T
------
K
Q
F
F
L
-
K
G
Q
Y
V
D
D
L
I
Y
S
Y
D
L
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------