@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs2077: (2015-12-13 )
MITYQEFLSEKDSLSFEVCTQYFQDLVNSLDEVDEYSIIYWKDFITASLIYSQSRGEWLLLSREEKHAKDDTRTTKHNKFIYTLKIYIAYSKQKGYEFPWFESIKDNRKQLGDLACYIAYIYAVNAR
Atome Classification :
(20 SA)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........-10........20..-.------.-----....30...--.....40..------..-....50..-..---------....60-.---..--.....70......-...80.-.--...--------...-----90......--------..-----------100..----.--....110.......120.....----------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MI
T
Y
Q
E
F
LS-EKDSL
S
F
E
V
C
T
Q
Y
F
-
Q
------
D
-----
L
V
N
S
L
D
EVD--E
Y
S
I
I
Y
W
K
D
------
F
I
-
T
A
S
L
I
Y
SQ-SR---------G
E
W
L
L
L
-S---RE--EKHAKD-DTRTTK-H
N
K
F
I
Y
-
T
--
L
K
I
--------
Y
I
A
-----
Y
SKQKGYE--------FP-----------
W
F
E
S
I
----
K
--
D
N
R
K
Q
L
G
D
L
A
C
Y
I
A
Y
I
Y
A
VNAR----------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
65.44
14%
-78
- C2 -
4JDN
2
?
A:
[6-149]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
F
N
N
F
P
I
T
-
N
K
I
Q
C
N
-
G
L
F
T
P
S
N
-
I
------
E
-----
T
L
L
G
G
T
E
I
G
--
K
F
T
V
T
P
K
S
S
GSMF--
L
V
-
S
A
D
I
I
A
S
R
M
E
G
---------
G
V
V
L
A
L
-
V
---
R
E
GD
S
K
P
C
A
I
-
S
Y
G
Y
S
S
-
G
V
P
N
L
C
-
S
--
L
R
T
--------
S
I
T
-----
N
T
G
L
T
P
T
T
--------
Y
S
L
R
V
G
G
LE
S
G
V
V
W
V
N
A
L
----
S
--
N
G
N
D
I
L
G
I
T
N
T
S
N
V
S
F
L
E
V
I
P
Q
----------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
65.28
18%
-84
* C4 *
2RDC
2
?
A:
[21-148]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
T
M
G
R
Y
-
K
------
K
-----
V
I
E
I
T
G
-
H
D
--
E
V
A
A
K
L
L
E
G
------
L
I
-
D
A
G
T
R
Y
F
S
-
K
V
V
E
M
E
H
R
M
A
S
A
R
F
R
L
D
-
G
E
E
L
R
E
--
L
T
E
T
L
D
-
R
S
R
R
L
A
-
H
E
S
L
I
S
-
S
--
L
H
V
--------
F
N
R
-----
Y
I
V
K
E
Y
G
E
E
L
K
E
A
GIE
G
G
-----------
I
F
P
K
P
----
E
AN
R
D
R
I
A
I
A
D
W
A
G
E
L
L
T
G
I
Y
E
N
R
H
----------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
64.07
20%
-70
- C5 -
4F9B
1
CDC7_HUMAN
A:
[102-172]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
H
E
S
F
L
D
-
I
L
N
S
L
S
F
Q
E
V
R
E
Y
M
-
L
------
N
-----
L
F
K
A
L
K
R
I
H
--
Q
F
G
I
V
H
-
R
D
------
V
K
-
P
S
N
F
L
Y
N
R
-
R
L
---------
K
K
Y
A
L
V
-
D
---
F
G
--
L
A
Q
G
T
H
-
D
T
K
I
E
L
-
L
K
F
V
Q
S
-
E
--
A
Q
Q
--------
V
A
P
-----
R
A
G
T
P
G
F
R
--------
A
P
-----------
E
V
L
T
K
----
C
--
P
N
Q
T
T
A
I
D
M
W
S
A
G
V
I
F
L
S
L
L
S
G
----------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
61.12
20%
-69
- C5 -
4F9C
1
CDC7_HUMAN
A:
[102-172]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
H
E
S
F
L
D
-
I
L
N
S
L
S
F
Q
E
V
R
E
Y
M
-
L
------
N
-----
L
F
K
A
L
K
R
I
H
--
Q
F
G
I
V
H
-
R
D
------
V
K
-
P
S
N
F
L
Y
N
R
-
R
L
---------
K
K
Y
A
L
V
-
D
---
F
G
--
L
A
Q
G
T
H
-
D
T
K
I
E
L
-
L
K
F
V
R
A
-
G
--
T
P
G
--------
F
R
A
-----
P
E
V
L
T
K
C
P
--------
N
Q
-----------
T
T
A
I
D
----
M
--
W
S
A
G
V
I
F
L
S
L
L
S
G
R
Y
P
F
Y
K
A
S
D
----------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
60.69
20%
-75
- C5 -
4F9A
2
CDC7_HUMAN
A:
[102-172]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
H
E
S
F
L
D
-
I
L
N
S
L
S
F
Q
E
V
R
E
Y
M
-
L
------
N
-----
L
F
K
A
L
K
R
I
H
--
Q
F
G
I
V
H
-
R
D
------
V
K
-
P
S
N
F
L
Y
N
R
-
R
L
---------
K
K
Y
A
L
V
-
D
---
F
G
--
L
A
Q
G
T
H
-
D
T
K
I
E
L
-
L
K
F
V
Q
S
-
E
--
A
Q
Q
--------
R
A
G
-----
T
P
G
F
R
A
P
E
--------
V
L
-----------
T
K
C
P
N
----
Q
--
T
T
A
I
D
M
W
S
A
G
V
I
F
L
S
L
L
S
G
R
Y
P
----------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
59.78
20%
-72
- C5 -
4F99
2
CDC7_HUMAN
A:
[102-172]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
H
E
S
F
L
D
-
I
L
N
S
L
S
F
Q
E
V
R
E
Y
M
-
L
------
N
-----
L
F
K
A
L
K
R
I
H
--
Q
F
G
I
V
H
-
R
D
------
V
K
-
P
S
N
F
L
Y
N
R
-
R
L
---------
K
K
Y
A
L
V
-
D
---
F
G
--
L
A
Q
G
T
H
-
D
T
K
I
E
L
-
L
K
F
V
Q
S
-
E
--
A
Q
Q
--------
R
A
G
-----
T
P
G
F
R
A
P
E
--------
V
L
-----------
T
K
C
P
N
----
Q
--
T
T
A
I
D
M
W
S
A
G
V
I
F
L
S
L
L
S
G
R
Y
P
----------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
59.50
24%
27
- C1 -
4OWT
-
INT3_HUMAN
A:
[1-466]
GGRL
L
L
S
T
SLDAKD
E
L
E
E
R
L
E
R
C
M
S
I
V
T
S
M
T
AGVS
E
R
E
A
N
D
A
L
N
A
Y
V
C
KG
L
P
Q
H
E
E
I
C
L
G
L
F
T
L
I
L
T
E
PAQ
A
Q
K
C
Y
R
D
L
A
L
V
SRDGM
N
I
V
L
N
K
I
N
Q
I
L
M
EKYLKLQ
D
T
C
R
T
Q
L
V
W
L
V
R
E
L
V
K
S
GVLG
A
D
G
V
C
M
T
F
M
K
Q
IAGGDVT
A
K
N
I
W
L
A
E
S
V
L
D
I
L
T
E
Q
R
E
W
V
L
K
S
S
I
L
I
A
M
A
V
Y
T
Y
L
R
L
I
V
D
HHG
T
A
Q
L
Q
A
L
R
Q
-
K
E
V
D
F
C
I
S
L
L
R
E
R
F
M
E
C
L
MIG
R
D
-----
L
V
R
L
L
Q
N
V
A
RI
P
E
F
E
L
L
W
K
D
------
I
I
H
N
P
Q
A
L
S
P
Q
-
F
T
---------
G
I
L
Q
L
L
Q
S
---
R
T
--
S
R
K
F
L
A
-
C
R
L
T
P
D
M
E
T
K
L
L
F
M
T
--
S
R
V
----------
R
-----
F
G
Q
Q
K
R
Y
Q
---------
D
-----------
W
F
Q
R
Q
YLST
P
--
D
S
Q
S
L
R
C
D
L
I
R
Y
I
C
G
V
V
H
P
S
N
E
V
L
S
SDILP
R
W
A
I
I
G
W
L
L
T
T
CTS
N
V
A
A
S
N
A
K
L
A
L
F
Y
DWLFFSPDKDSIMNI
E
P
A
I
L
V
M
H
H
S
MKPH
P
A
I
T
A
T
L
L
D
F
M
C
R
I
I
P
N
FYPPL
E
G
H
V
R
Q
G
V
F
S
S
L
N
H
I
V
E
K
RVLAHL
A
P
L
F
D
NPKLD
K
E
L
R
A
M
L
R
E
K
FPEFCS
40
Fugue
55.90
18%
8
- C4 -
1IGN
3
RAP1_YEAST
A:
[94-242]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
R
K
F
S
A
D
-
E
D
Y
T
L
A
I
A
V
K
K
Q
F
Y
-
R
------
D
-----
L
F
Q
-
I
D
P
D
T
--
G
R
S
L
I
R
T
Q
S
------
R
R
-
G
-----
P
I
-
A
R
---------
E
F
F
K
H
F
-
A
---
E
E
--
H
A
A
H
T
E
-
N
A
W
R
D
R
-
F
R
K
F
L
L
-
A
YG
I
D
D
--------
Y
I
S
-----
Y
Y
E
A
E
--------------------------
E
P
M
----
K
--
N
L
T
P
T
P
G
N
Y
N
S
---------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
53.53
20%
-4
- C4 -
2KPO
-
?
A:
[1-110]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
L
L
Y
V
L
I
I
S
-
N
D
K
K
L
I
E
E
A
R
K
M
A
E
-
K
------
A
N
L
E
L
R
T
V
K
T
E
D
E
L
K
--
K
Y
L
E
E
F
R
K
E
------
S
Q
-
N
I
K
V
L
I
L
V
-
S
N
---------
D
E
E
L
D
K
-
A
---
K
E
--
L
A
Q
K
M
E
I
D
V
R
T
R
K
-
V
T
S
P
D
E
-
A
--
K
R
W
--------
I
K
E
-----
F
S
E
E
G
G
--------------------------
S
L
----
E
--
H
H
H
H
H
H
--------------------------------------------------------------------------------------------------------------------------------------------------------
39
Fugue
52.15
18%
-56
- C4 -
2STW
2
A:
[1-96]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
I
P
A
A
A
L
A
G
-
Y
T
G
S
G
P
----
I
Q
L
W
-
Q
------
F
-----
L
L
E
L
L
T
D
K
S
--
C
Q
S
F
I
S
W
T
G
----------
D
G
W
E
F
K
L
-
S
-----------
D
P
D
E
V
-
A
---
R
R
--
W
G
K
R
K
N
-
K
P
-
K
M
N
-
Y
E
K
L
S
R
-
G
--
L
R
Y
--------
Y
Y
D
KN
I
I
H
K
T
A
G
K
R
Y
V
--------
Y
R
-----------
F
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
46.39
4%
-97
- C3 -
4WT5
-
?
A:
[8-157]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IPVVRLKFG
E
V
A
E
A
T
S
V
V
-
V
L
P
V
C
K
A
E
E
G
E
K
K
I
-
L
------
E
-----
A
P
M
E
I
I
A
G
G
--
D
F
K
V
V
E
A
E
K
GWK
R
W
V
V
L
-
P
S
W
N
P
V
A
A
-
I
G
---------
K
G
G
V
A
V
-
S
---
F
R
--
D
R
K
V
L
P
-
W
D
G
K
E
E
-
P
L
L
V
V
A
-
D
--
R
V
R
NVVEADD
G
Y
Y
L
-----
V
V
A
E
N
G
L
K
--------
L
E
-----------
K
G
S
D
L
----
K
--
A
R
E
V
K
-
E
S
L
G
M
V
V
L
V
V
R
P
P
R
E
D
----------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
45.75
13%
-153
- C5 -
3AX1
-
A:
[2-32]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
M
S
Y
K
Q
F
I
Q
E
L
E
D
D
I
L
P
S
E
A
E
R
R
Y
-
Q
------
E
-----
Y
K
S
E
Y
I
T
T
Q
--
K
R
A
F
F
N
T
H
K
------
E
E
-
D
W
L
K
N
K
Y
H
-
P
T
---------
N
L
L
S
V
I
-
E
---
R
R
--
N
D
L
A
Q
K
-
V
A
K
D
F
L
-
L
D
L
Q
S
G
-
T
--
L
D
L
--------
G
P
A
-----
V
T
A
L
N
A
A
P
--------
K
A
-----------
P
S
F
T
S
----
D
--
P
K
R
I
L
T
D
V
E
Q
T
Q
A
L
V
R
K
L
D
S
E
K
----------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
45.57
36%
-118
- C5 -
1JKL
-
DAPK1_HUMAN
A:
[102-126]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
L
A
-
E
K
E
S
L
T
E
E
E
A
T
E
F
L
-
K
------
Q
-----
I
L
N
G
V
Y
Y
L
H
--
S
L
Q
I
A
H
F
D
L
------
K
P
-
E
N
I
M
L
L
D
R
-
N
V
---------
P
K
P
R
I
K
-
I
---
I
D
--
F
G
L
A
H
K
-
I
D
F
G
N
E
-
F
K
N
I
F
G
-
T
--
P
E
F
--------
V
A
P
-----
E
I
V
N
Y
E
P
L
--------
G
L
-----------
E
A
D
M
W
----
S
--
I
G
V
I
T
Y
I
L
L
S
G
A
S
P
F
L
G
D
T
K
Q
E
----------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
45.35
36%
-121
- C5 -
4YO4
-
DAPK1_HUMAN
A:
[102-126]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
L
A
-
E
K
E
S
L
T
E
E
E
A
T
E
F
L
-
K
------
Q
-----
I
L
N
G
V
Y
Y
L
H
--
S
L
Q
I
A
H
F
D
L
------
K
P
-
E
N
I
M
L
L
D
R
-
N
V
---------
P
K
P
R
I
K
-
I
---
I
D
--
F
G
L
A
H
K
-
I
D
F
G
N
E
-
F
K
N
I
F
G
-
T
--
P
E
F
--------
V
A
P
-----
E
I
V
N
Y
E
P
L
--------
G
L
-----------
E
A
D
M
W
----
S
--
I
G
V
I
T
Y
I
L
L
S
G
A
S
P
F
L
G
D
T
K
Q
E
----------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
45.01
36%
-122
- C5 -
4YPD
-
DAPK1_HUMAN
A:
[102-126]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
L
A
-
E
K
E
S
L
T
E
E
E
A
T
E
F
L
-
K
------
Q
-----
I
L
N
G
V
Y
Y
L
H
--
S
L
Q
I
A
H
F
D
L
------
K
P
-
E
N
I
M
L
L
D
R
-
N
V
---------
P
K
P
R
I
K
-
I
---
I
D
--
F
G
L
A
H
K
-
I
D
F
G
N
E
-
F
K
N
I
F
G
-
T
--
P
E
F
--------
V
A
P
-----
E
I
V
N
Y
E
P
L
--------
G
L
-----------
E
A
D
M
W
----
S
--
I
G
V
I
T
Y
I
L
L
S
G
A
S
P
F
L
G
D
T
K
Q
E
----------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
44.91
36%
-123
- C5 -
3EH9
-
DAPK1_HUMAN
A:
[102-126]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
L
A
-
E
K
-
S
L
T
E
E
E
A
T
E
F
L
-
K
------
Q
-----
I
L
N
G
V
Y
Y
L
H
--
S
L
Q
I
A
H
F
D
L
------
K
P
-
E
N
I
M
L
L
D
R
-
N
V
---------
P
K
P
R
I
K
-
I
---
I
D
--
F
G
L
A
H
K
-
I
D
F
G
N
E
-
F
K
N
I
F
G
-
T
--
P
E
F
--------
V
A
P
-----
E
I
V
N
Y
E
P
L
--------
G
L
-----------
E
A
D
M
W
----
S
--
I
G
V
I
T
Y
I
L
L
S
G
A
S
P
F
L
G
D
T
K
Q
E
----------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
44.75
36%
-118
- C5 -
3EHA
-
DAPK1_HUMAN
A:
[102-126]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
L
A
-
E
K
-
S
L
T
E
E
E
A
T
E
F
L
-
K
------
Q
-----
I
L
N
G
V
Y
Y
L
H
--
S
L
Q
I
A
H
F
D
L
------
K
P
-
E
N
I
M
L
L
D
R
-
N
V
---------
P
K
P
R
I
K
-
I
---
I
D
--
F
G
L
A
H
K
-
I
D
F
G
N
E
-
F
K
N
I
F
G
-
T
--
P
E
F
--------
V
A
P
-----
E
I
V
N
Y
E
P
L
--------
G
L
-----------
E
A
D
M
W
----
S
--
I
G
V
I
T
Y
I
L
L
S
G
A
S
P
F
L
G
D
T
K
Q
E
----------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
44.26
36%
-116
- C5 -
1IG1
-
DAPK1_HUMAN
A:
[102-126]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
L
A
-
E
K
E
S
L
T
E
E
E
A
T
E
F
L
-
K
------
Q
-----
I
L
N
G
V
Y
Y
L
H
--
S
L
Q
I
A
H
F
D
L
------
K
P
-
E
N
I
M
L
L
D
R
-
N
V
---------
P
K
P
R
I
K
-
I
---
I
D
--
F
G
L
A
H
K
-
I
D
F
G
N
E
-
F
K
N
I
F
G
-
T
--
P
E
F
--------
V
A
P
-----
E
I
V
N
Y
E
P
L
--------
G
L
-----------
E
A
D
M
W
----
S
--
I
G
V
I
T
Y
I
L
L
S
G
A
S
P
F
L
G
D
T
K
Q
E
----------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
44.04
20%
-79
* C5 *
3KDW
5
?
A:
[141-181]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
Y
K
A
T
V
D
-
M
I
P
T
L
K
E
E
E
K
A
Q
I
M
-
A
------
W
-----
L
V
E
A
-----------------------
R
-
E
F
A
M
D
A
E
N
-
S
N
---------
K
K
H
A
A
F
-
G
---
K
Y
--
K
G
R
I
N
N
-
Y
L
S
K
R
G
-
Y
D
L
V
K
E
-
R
--
K
A
W
--------
Y
E
R
-----
I
K
A
R
G
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
43.89
36%
-108
- C5 -
1JKS
-
DAPK1_HUMAN
A:
[103-127]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
L
A
-
E
K
E
S
L
T
E
E
E
A
T
E
F
L
-
K
------
Q
-----
I
L
N
G
V
Y
Y
L
H
--
S
L
Q
I
A
H
F
D
L
------
K
P
-
E
N
I
M
L
L
D
R
-
N
V
---------
P
K
P
R
I
K
-
I
---
I
D
--
F
G
L
A
H
K
-
I
D
F
G
N
E
-
F
K
N
I
F
G
-
T
--
P
E
F
--------
V
A
P
-----
E
I
V
N
Y
E
P
L
--------
G
L
-----------
E
A
D
M
W
----
S
--
I
G
V
I
T
Y
I
L
L
S
G
A
S
P
F
L
G
D
T
K
Q
E
----------------------------------------------------------------------------------------------------------------------------------------