@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu00020: (2016-06-01 )
MKFTIQKDRLVESVQDVLKAVSSRTTIPILTGIKIVASDDGVSFTGSDSDISIESFIPKEEGDKEIVTIEQPGSIVLQARFFSEIVKKLPMATVEIEVQNQYLTIIRSGKAEFNLNGLDADEYPHLPQIEEHHAIQIPTDLLKNLIRQTVFAVSTSETRPILTGVNWKVEQSELLCTATDSHRLALRKAKLDIPEDRSYNVVIPGKSLTELSKILDDNQELVDIVITETQVLFKAKNVLFFSRLLDGNYPDTTSLIPQDSKTEIIVNTKEFLQAIDRASLLAREGRNNVVKLSAKPAESIEISSNSPEIGKVVEAIVADQIEGEELNISFSPKYMLDALKVLEGAEIRVSFTGAMRPFLIRTPNDETIVQLILPVRTY
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90..-.-......100...-....110.......120.......130.......140.......150.......160.......-170.-.......180.......190-....-....200.......210......-.-220......-------.230.......240.......250.......260.......270.......280...-....290.....-..300.......310.......320.......330.......340.......350......-.360..---------------.--....370......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MKFT
I
Q
K
D
R
L
V
E
S
V
Q
D
V
L
K
A
V
SSRT
T
I
P
I
L
T
G
I
K
I
V
ASDD
G
V
S
FTGSDSDI
S
I
E
SFIPKEEGDK
E
I
V
T
IEQP
G
S
I
V
L
Q
A
R
F
F
S
E
I
V
K
KLP-
M
A
-
T
-
V
E
I
E
V
QN
Q
Y
L
T
I
-
I
RSGK
A
E
F
NLNGL
D
A
DEYPHLPQIEEHHAIQI
P
T
D
L
L
K
N
L
I
R
Q
T
V
F
AVSTSETR
P
I
L
TGV
N
W
K
V
-EQ-
S
-
E
L
L
C
TATDSH
R
L
A
L
R
K
AKL--DIPE-DRS
Y
N
V
V
IPGK
S
L
T
E
L
S
K
I
LDDN-Q-
E
L
V
D
I
V
I
TE-------
T
Q
V
L
F
K
AK
N
V
L
F
F
S
R
L
LDGNYPDTTSLIPQDSK
T
E
I
I
V
N
T
K
E
F
L
Q
A
I
D
R
A
S
L
L
A
REG-RN
N
V
V
K
L
SAKPA-
E
S
I
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ISSNSP
E
I
G
K
V
V
E
A
I
V
A
DQIEG
E
E
L
N
I
S
FS
P
K
Y
M
L
D
A
L
K
V
LEG
A
E
I
R
V
S
F
TGAM
R
P
F
-
L
I
RTPN---------------D--E
T
I
V
Q
L
I
LPVRTY
25
HHSearch
98.78
99%
-132
- C2 -
4TR6
-
DPO3B_BACSU
A:
[3-380]
M
K
F
T
I
Q
K
D
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L
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S
V
Q
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L
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A
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D
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N
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V
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D
N
-
Q
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L
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D
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-------
T
Q
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L
F
K
A
K
N
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F
S
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L
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N
Y
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T
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S
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T
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N
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L
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L
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V
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-
L
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R
T
P
N
---------------
D
--
E
T
I
V
Q
L
I
L
P
V
R
T
Y
1
PsiBlast_PDB
98.22
100%
-128
- C2 -
4TR6
-
DPO3B_BACSU
A:
[3-379]
M
K
F
T
I
Q
K
D
R
L
V
E
S
V
Q
D
V
L
K
A
V
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Q
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L
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T
G
V
N
W
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-
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Q
-
S
-
E
L
L
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T
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T
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A
L
R
K
A
K
L
--
D
I
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-
D
R
S
Y
N
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V
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K
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L
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D
N
-
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L
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D
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-------
T
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F
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A
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A
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F
-
L
I
R
T
P
N
---------------
D
--
E
T
I
V
Q
L
I
L
P
V
R
T
-
22
HHSearch
78.06
37%
-117
- C2 -
2AVT
-
?
A:
[2-377]
I
Q
F
S
I
N
R
T
L
F
I
H
A
L
N
T
T
K
R
A
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A
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G
S
N
G
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I
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N
T
I
P
V
------
G
L
L
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L
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A
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F
F
I
N
I
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P
-
D
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V
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P
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A
A
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-
S
N
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A
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R
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D
N
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-------
S
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T
L
T
P
G
D
---------------
E
E-
E
S
F
I
Q
L
I
T
P
V
R
T
-
3
PsiBlast_PDB
77.69
37%
-113
- C2 -
2AVT
-
?
A:
[2-377]
I
Q
F
S
I
N
R
T
L
F
I
H
A
L
N
T
T
K
R
A
I
S
T
K
N
A
I
P
I
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I
K
I
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T
G
V
T
L
T
G
S
N
G
Q
I
S
I
E
N
T
I
P
V
-----
G
L
L
-
I
T
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L
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F
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N
I
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P
-
D
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D
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A
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G
---------------
D
EE
E
S
F
I
Q
L
I
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P
V
R
T
-
2
PsiBlast_PDB
77.01
41%
-107
- C2 -
2AWA
1
DPO3B_STRPN
A:
[16-389]
--
F
S
I
N
K
N
L
F
L
Q
A
L
N
T
T
K
R
A
I
S
S
K
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--
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F
A
N
-------
N
Q
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Y
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L
L
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A
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A
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--
V
V
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V
P
A
D
T
---------------
D
--
E
D
F
M
Q
L
I
T
P
V
R
T
-
24
HHSearch
73.73
34%
-121
- C2 -
3T0P
14
?
A:
[2-366]
M
K
L
I
C
S
K
A
N
L
L
K
G
V
N
I
V
S
K
A
V
P
T
R
T
T
M
A
I
L
E
C
I
L
I
D
A
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A
N
E
I
K
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M
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G
I
E
T
I
I
D
G
--------
T
I
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R
G
I
I
A
L
D
A
K
I
F
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E
I
V
R
K
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-
D
N
-
D
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A
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-
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A
K
F
N
I
I
G
K
S
G
D
D
F
S
Y
I
P
Y
V
E
R
N
E
S
I
V
L
S
Q
F
T
L
K
E
V
I
R
Q
T
I
F
S
I
A
D
N
D
N
N
K
L
M
T
G
E
L
F
E
I
-
E
E
-
N
-
K
L
R
V
V
S
L
D
G
H
R
I
S
I
R
Y
I
E
M
--
K
N
H
--
Y
D
S
K
K
V
V
V
P
G
K
T
L
Q
E
I
S
K
I
I
P
G
S
-
A
D
E
D
V
V
I
Y
I
T
N
-------
N
H
I
V
F
E
F
E
N
T
T
V
V
S
R
L
I
E
G
E
Y
F
K
I
D
Q
M
L
S
S
D
Y
D
T
K
V
R
I
N
K
R
E
L
L
D
C
I
D
R
A
T
L
L
V
K
E
D
-
K
K
-
P
I
I
M
N
I
T
-
D
-
G
N
M
E
L
R
I
N
S
-
F
I
G
S
M
N
E
D
I
D
I
-
D
K
D
G
K
D
I
M
I
G
F
N
P
K
F
F
I
D
A
L
R
V
I
D
E
E
E
V
N
L
Y
M
V
N
P
K
A
P
C
-
F
I
K
D
D
----------------
E
--
G
K
F
I
Y
L
I
L
P
V
N
F
-
4
PsiBlast_PDB
70.90
33%
-117
- C2 -
3T0P
14
?
A:
[3-364]
-
K
L
I
C
S
K
A
N
L
L
K
G
V
N
I
V
S
K
A
V
P
T
R
T
T
M
A
I
L
E
C
I
L
I
D
A
S
A
N
E
I
K
L
M
A
N
D
M
E
L
G
I
E
T
I
I
D
G
--------
T
I
E
E
R
G
I
I
A
L
D
A
K
I
F
S
E
I
V
R
K
L
P
-
D
N
-
D
-
V
T
I
E
T
D
A
S
F
K
T
V
-
I
S
C
E
K
A
K
F
N
I
I
G
K
S
G
D
D
F
S
Y
I
P
Y
V
E
R
N
E
S
I
V
L
S
Q
F
T
L
K
E
V
I
R
Q
T
I
F
S
I
A
D
N
D
N
N
K
L
M
T
G
E
L
F
E
I
-
E
E
-
N
-
K
L
R
V
V
S
L
D
G
H
R
I
S
I
R
Y
I
E
M
--
K
N
H
Y
-
D
-
S
K
K
V
V
V
P
G
K
T
L
Q
E
I
S
K
I
I
P
G
S
A
D
-
E
D
V
V
I
Y
I
T
N
-------
N
H
I
V
F
E
F
E
N
T
T
V
V
S
R
L
I
E
G
E
Y
F
K
I
D
Q
M
L
S
S
D
Y
D
T
K
V
R
I
N
K
R
E
L
L
D
C
I
D
R
A
T
L
L
V
K
E
--
D
K
K
P
I
I
M
N
I
T
D
G
--
N
M
E
L
R
I
N
S
F
-
I
G
S
M
N
E
D
I
D
I
-
D
K
D
G
K
D
I
M
I
G
F
N
P
K
F
F
I
D
A
L
R
V
I
D
E
E
E
V
N
L
Y
M
V
N
P
K
A
P
C
-
F
I
K
-
D
D
---------------
E
--
G
K
F
I
Y
L
I
L
P
V
---
12
PsiBlast_PDB
69.84
26%
-109
- C2 -
3D1F
4
DPO3B_ECOLI
A:
[1-365]
M
K
F
T
V
E
R
E
H
L
L
K
P
L
Q
Q
V
S
G
P
L
G
G
R
P
T
L
P
I
L
G
N
L
L
L
Q
V
A
D
G
T
L
S
L
T
G
T
D
L
E
M
E
M
V
A
R
V
-------
A
L
V
Q
P
H
E
P
G
A
T
T
V
P
A
R
K
F
F
D
I
C
R
G
L
P
E
G
A
-
E
-
I
A
V
Q
L
E
G
E
R
M
-
L
-
V
R
S
G
R
S
R
F
S
L
S
T
L
P
A
A
D
F
P
N
L
D
D
W
Q
S
E
V
E
F
T
L
P
Q
A
T
M
K
R
L
I
E
A
T
Q
F
S
M
A
H
Q
D
V
R
Y
Y
L
N
G
M
L
F
E
T
-
E
G
-
E
-
E
L
R
T
V
A
T
D
G
H
R
L
A
V
C
S
M
P
I
G
Q
S
L
P
----
S
H
S
V
I
V
P
R
K
G
V
I
E
L
M
R
M
L
D
G
G
-
D
-
N
P
L
R
V
Q
I
G
S
-------
N
N
I
R
A
H
V
G
D
F
I
F
T
S
K
L
V
D
G
R
F
P
D
Y
R
R
V
L
P
K
N
P
D
K
H
L
E
A
G
C
D
L
L
K
Q
A
F
A
R
A
A
I
L
S
N
E
K
-
F
R
G
V
R
L
Y
V
S
E
---
N
Q
L
K
I
T
A
N
N
P
E
-
Q
E
E
A
E
E
I
L
D
V
T
Y
S
G
A
E
M
E
I
G
F
N
V
S
Y
V
L
D
V
L
N
A
L
K
C
E
N
V
R
M
M
L
T
D
S
V
S
S
V
-
Q
I
E
D
A
A
---------------
S
--
Q
S
A
A
Y
V
V
M
P
M
R
--
21
HHSearch
69.23
26%
-111
- C2 -
1VPK
-
?
A:
[1-366]
M
K
V
T
V
T
T
L
E
L
K
D
K
I
T
I
A
S
K
A
L
A
K
K
S
V
K
P
I
L
A
G
F
L
F
E
V
K
D
G
N
F
Y
I
C
A
T
D
L
E
T
G
V
K
A
T
V
N
A
A
-------
E
I
S
G
E
A
R
F
V
V
P
G
D
V
I
Q
K
M
V
K
V
L
P
-
D
E
-
I
-
T
E
L
S
L
E
G
D
--
A
L
V
I
S
S
G
S
T
V
F
R
I
T
T
M
P
A
D
E
F
P
E
I
T
P
A
E
S
G
I
T
F
E
V
D
T
S
L
L
E
E
M
V
E
K
V
I
F
A
A
A
K
D
E
F
M
R
N
L
N
G
V
F
W
E
L
-
H
K
-
N
-
L
L
R
L
V
A
S
D
G
F
R
L
A
L
A
E
E
Q
I
--
E
N
---
E
E
E
A
S
F
L
L
S
L
K
S
M
K
E
V
Q
N
V
L
D
N
T
-
T
E
P
T
I
T
V
R
Y
D
G
-------
R
R
V
S
L
S
T
N
D
V
E
T
V
M
R
V
V
D
A
E
F
P
D
Y
K
R
V
I
P
E
T
F
K
T
K
V
V
V
S
R
K
E
L
R
E
S
L
K
R
V
M
V
I
A
S
K
G
-
S
E
-
S
V
K
F
E
I
E
-
E
-
N
V
M
R
L
V
S
K
S
P
D
Y
G
E
V
V
D
E
V
E
V
-
Q
K
E
G
E
D
L
V
I
A
F
N
P
K
F
I
E
D
V
L
K
H
I
E
T
E
E
I
E
M
N
F
V
D
S
T
S
P
C
-
Q
I
N
P
L
D
---------------
I
--
S
G
Y
L
Y
I
V
M
P
I
R
L
A
23
HHSearch
69.21
27%
-113
- C2 -
4K3L
7
DPO3B_ECOLI
A:
[1-365]
M
K
F
T
V
E
R
E
H
L
L
K
P
L
Q
Q
V
S
---------
P
I
L
G
N
L
L
L
Q
V
A
D
G
T
L
S
L
T
G
T
D
L
E
M
E
M
V
A
R
V
A
L
V
-------
Q
P
H
E
P
G
A
T
T
V
P
A
R
K
F
F
D
I
C
R
G
L
P
-
E
G
A
E
-
I
A
V
Q
L
E
G
E
--
R
M
L
V
R
S
G
R
S
R
F
S
L
S
T
L
P
A
A
D
F
P
N
L
D
D
W
Q
S
E
V
E
F
T
L
P
Q
A
T
M
K
R
L
I
E
A
T
Q
F
S
M
A
H
Q
D
V
R
Y
Y
L
N
G
M
L
F
E
T
-
E
G
-
E
-
E
L
R
T
V
A
T
D
G
H
R
L
A
V
C
S
M
P
I
--
G
Q
S
--
L
P
S
H
S
V
I
V
P
R
K
G
V
I
E
L
M
R
M
L
D
-----
N
P
L
R
V
Q
I
G
S
-------
N
N
I
R
A
H
V
G
D
F
I
F
T
S
K
L
V
D
G
R
F
P
D
Y
R
R
V
L
P
K
N
P
D
K
H
L
E
A
G
C
D
L
L
K
Q
A
F
A
R
A
A
I
L
S
N
E
K
-
F
R
-
G
V
R
L
Y
V
S
-
E
-
N
Q
L
K
I
T
A
N
N
P
E
Q
E
E
A
E
E
I
L
D
V
-
T
Y
S
G
A
E
M
E
I
G
F
N
V
S
Y
V
L
D
V
L
N
A
L
K
C
E
N
V
R
M
M
L
T
D
S
V
S
S
V
-
Q
I
E
D
A
A
---------------
S
--
Q
S
A
A
Y
V
V
M
P
M
R
--
16
PsiBlast_PDB
68.89
26%
-116
- C2 -
3Q4K
1
DPO3B_ECOLI
A:
[1-365]
M
K
F
T
V
E
R
E
H
L
L
K
P
L
Q
Q
V
S
-------
T
L
P
I
L
G
N
L
L
L
Q
V
A
D
G
T
L
S
L
T
G
T
D
L
E
M
E
M
V
A
R
V
-------
A
L
V
Q
P
H
E
P
G
A
T
T
V
P
A
R
K
F
F
D
I
C
R
G
L
P
E
G
A
-
E
-
I
A
V
Q
L
E
G
E
R
M
-
L
-
V
R
S
G
R
S
R
F
S
L
S
T
L
P
A
A
D
F
P
N
L
D
D
W
Q
S
E
V
E
F
T
L
P
Q
A
T
M
K
R
L
I
E
A
T
Q
F
S
M
A
H
Q
D
V
R
Y
Y
L
N
G
M
L
F
E
T
-
E
G
-
E
-
E
L
R
T
V
A
T
D
G
H
R
L
A
V
C
S
M
P
I
G
Q
S
L
P
----
S
H
S
V
I
V
P
R
K
G
V
I
E
L
M
R
M
L
D
G
G
-
D
-
N
P
L
R
V
Q
I
G
S
-------
N
N
I
R
A
H
V
G
D
F
I
F
T
S
K
L
V
D
G
R
F
P
D
Y
R
R
V
L
P
--
P
D
K
H
L
E
A
G
C
D
L
L
K
Q
A
F
A
R
A
A
I
L
S
N
E
K
-
F
R
G
V
R
L
Y
V
S
E
---
N
Q
L
K
I
T
A
N
N
P
E
-
Q
E
E
A
E
E
I
L
D
V
T
Y
S
G
A
E
M
E
I
G
F
N
V
S
Y
V
L
D
V
L
N
A
L
K
C
E
N
V
R
M
M
L
T
D
S
V
S
S
V
-
Q
I
E
D
A
A
---------------
S
--
Q
S
A
A
Y
V
V
M
P
M
R
--
27
HHSearch
68.81
28%
-106
- C2 -
5AGV
11
DPO3B_MYCTU
A:
[17-405]
L
T
F
R
L
L
R
E
S
F
A
D
A
V
S
W
V
A
K
N
L
P
A
R
P
A
V
P
V
L
S
G
V
L
L
T
G
S
D
N
G
L
T
I
S
G
F
D
Y
E
V
S
A
E
A
Q
V
G
A
--------
E
I
V
S
P
G
S
V
L
V
S
G
R
L
L
S
D
I
T
R
A
L
P
-
N
K
-
P
-
V
D
V
H
V
E
G
N
--
R
V
A
L
T
C
G
N
A
R
F
S
L
P
T
M
P
V
E
D
Y
P
T
L
P
T
L
P
E
-
E
T
G
L
L
P
A
E
L
F
A
E
A
I
S
Q
V
A
I
A
A
G
R
D
D
T
L
P
M
L
T
G
I
R
V
E
I
-
L
G
-
E
-
T
V
V
L
A
A
T
D
R
F
R
L
A
V
R
E
L
K
W
--
S
A
S
S
P
D
I
E
A
A
V
L
V
P
A
K
T
L
A
E
A
A
K
A
G
I
G
G
---
S
D
V
R
L
S
L
G
T
GPGVGKD
G
L
L
G
I
S
G
N
G
K
R
S
T
T
R
L
L
D
A
E
F
P
K
F
R
Q
L
L
P
T
E
H
T
A
V
A
T
M
D
V
A
E
L
I
E
A
I
K
L
V
A
L
V
A
D
R
--
G
A
-
Q
V
R
M
E
F
A
-
D
-
G
S
V
R
L
S
A
G
A
D
D
V
G
R
A
E
E
D
L
V
V
-
D
Y
A
G
E
P
L
T
I
A
F
N
P
T
Y
L
T
D
G
L
S
S
L
R
S
E
R
V
S
F
G
F
T
T
A
G
K
P
A
-
L
L
R
P
V
S
GDDRPLNGNGPFPAV
S
--
T
D
Y
V
Y
L
L
M
P
V
R
L
P
18
PsiBlast_PDB
68.79
26%
-113
- C2 -
4K3L
7
DPO3B_ECOLI
A:
[1-365]
M
K
F
T
V
E
R
E
H
L
L
K
P
L
Q
Q
V
S
---------
P
I
L
G
N
L
L
L
Q
V
A
D
G
T
L
S
L
T
G
T
D
L
E
M
E
M
V
A
R
V
-------
A
L
V
Q
P
H
E
P
G
A
T
T
V
P
A
R
K
F
F
D
I
C
R
G
L
P
E
G
A
-
E
-
I
A
V
Q
L
E
G
E
R
M
-
L
-
V
R
S
G
R
S
R
F
S
L
S
T
L
P
A
A
D
F
P
N
L
D
D
W
Q
S
E
V
E
F
T
L
P
Q
A
T
M
K
R
L
I
E
A
T
Q
F
S
M
A
H
Q
D
V
R
Y
Y
L
N
G
M
L
F
E
T
-
E
G
-
E
-
E
L
R
T
V
A
T
D
G
H
R
L
A
V
C
S
M
P
I
G
Q
S
L
P
----
S
H
S
V
I
V
P
R
K
G
V
I
E
L
M
R
M
L
D
-----
N
P
L
R
V
Q
I
G
S
-------
N
N
I
R
A
H
V
G
D
F
I
F
T
S
K
L
V
D
G
R
F
P
D
Y
R
R
V
L
P
K
N
P
D
K
H
L
E
A
G
C
D
L
L
K
Q
A
F
A
R
A
A
I
L
S
N
E
K
-
F
R
G
V
R
L
Y
V
S
E
---
N
Q
L
K
I
T
A
N
N
P
E
-
Q
E
E
A
E
E
I
L
D
V
T
Y
S
G
A
E
M
E
I
G
F
N
V
S
Y
V
L
D
V
L
N
A
L
K
C
E
N
V
R
M
M
L
T
D
S
V
S
S
V
-
Q
I
E
D
A
A
---------------
S
--
Q
S
A
A
Y
V
V
M
P
M
R
--
8
PsiBlast_PDB
68.64
26%
-108
- C2 -
1UNN
-
DPO3B_ECOLI
A:
[1-365]
M
K
F
T
V
E
R
E
H
L
L
K
P
L
Q
Q
V
S
G
P
L
G
G
R
P
T
L
P
I
L
G
N
L
L
L
Q
V
A
D
G
T
L
S
L
T
G
T
D
L
E
M
E
M
V
A
R
V
-------
A
L
V
Q
P
H
E
P
G
A
T
T
V
P
A
R
K
F
F
D
I
C
R
G
L
P
E
G
A
-
E
-
I
A
V
Q
L
E
G
E
R
M
-
L
-
V
R
S
G
R
S
R
F
S
L
S
T
L
P
A
A
D
F
P
N
L
D
D
W
Q
S
E
V
E
F
T
L
P
Q
A
T
M
K
R
L
I
E
A
T
Q
F
S
M
A
H
Q
D
V
R
Y
Y
L
N
G
M
L
F
E
T
-
E
G
-
E
-
E
L
R
T
V
A
T
D
G
H
R
L
A
V
C
S
M
P
I
GQ
S
L
P
----
S
H
S
V
I
V
P
R
K
G
V
I
E
L
M
R
M
L
D
G
G
-
D
-
N
P
L
R
V
Q
I
G
S
-------
N
N
I
R
A
H
V
G
D
F
I
F
T
S
K
L
V
D
G
R
F
P
D
Y
R
R
V
L
P
K
N
P
D
K
H
L
E
A
G
C
D
L
L
K
Q
A
F
A
R
A
A
I
L
S
N
E
K
-
F
R
G
V
R
L
Y
V
S
E
---
N
Q
L
K
I
T
A
N
N
P
E
-
Q
E
E
A
E
E
I
L
D
V
T
Y
S
G
A
E
M
E
I
G
F
N
V
S
Y
V
L
D
V
L
N
A
L
K
C
E
N
V
R
M
M
L
T
D
S
V
S
S
V
-
Q
I
E
D
A
A
---------------
S
--
Q
S
A
A
Y
V
V
M
P
M
R
--
9
PsiBlast_PDB
68.62
26%
-108
- C2 -
1OK7
-
DPO3B_ECOLI
A:
[1-365]
M
K
F
T
V
E
R
E
H
L
L
K
P
L
Q
Q
V
S
G
P
L
G
G
R
P
T
L
P
I
L
G
N
L
L
L
Q
V
A
D
G
T
L
S
L
T
G
T
D
L
E
M
E
M
V
A
R
V
-------
A
L
V
Q
P
H
E
P
G
A
T
T
V
P
A
R
K
F
F
D
I
C
R
G
L
P
E
G
A
-
E
-
I
A
V
Q
L
E
G
E
R
M
-
L
-
V
R
S
G
R
S
R
F
S
L
S
T
L
P
A
A
D
F
P
N
L
D
D
W
Q
S
E
V
E
F
T
L
P
Q
A
T
M
K
R
L
I
E
A
T
Q
F
S
M
A
H
Q
D
V
R
Y
Y
L
N
G
M
L
F
E
T
-
E
G
-
E
-
E
L
R
T
V
A
T
D
G
H
R
L
A
V
C
S
M
P
I
G
Q
S
L
P
----
S
H
S
V
I
V
P
R
K
G
V
I
E
L
M
R
M
L
D
G
G
-
D
-
N
P
L
R
V
Q
I
G
S
-------
N
N
I
R
A
H
V
G
D
F
I
F
T
S
K
L
V
D
G
R
F
P
D
Y
R
R
V
L
P
K
N
P
D
K
H
L
E
A
G
C
D
L
L
K
Q
A
F
A
R
A
A
I
L
S
N
E
K
-
F
R
G
V
R
L
Y
V
S
E
---
N
Q
L
K
I
T
A
N
N
P
E
-
Q
E
E
A
E
E
I
L
D
V
T
Y
S
G
A
E
M
E
I
G
F
N
V
S
Y
V
L
D
V
L
N
A
L
K
C
E
N
V
R
M
M
L
T
D
S
V
S
S
V
-
Q
I
E
D
A
A
---------------
S
--
Q
S
A
A
Y
V
V
M
P
M
R
--
26
HHSearch
68.24
27%
-113
* C2 *
4TR8
1
?
A:
[17-382]
M
H
F
T
I
Q
R
E
A
L
L
K
P
L
Q
L
V
A
G
V
V
E
---
T
L
P
V
L
S
N
V
L
L
V
V
E
G
Q
Q
L
S
L
T
G
T
D
L
E
V
E
L
V
G
R
V
V
L
E
-------
D
A
A
E
P
G
E
I
T
V
P
A
R
K
L
M
D
I
C
K
S
L
P
-
N
D
-
V
L
I
D
I
R
V
E
E
Q
--
K
L
L
V
K
A
G
R
S
R
F
T
L
S
T
L
P
A
N
D
F
P
T
V
E
E
G
P
G
S
L
N
F
S
I
A
Q
S
K
L
R
R
L
I
D
R
T
S
F
A
M
A
Q
Q
D
V
R
Y
Y
L
N
G
M
L
L
E
V
-
N
G
-
G
-
T
L
R
S
V
A
T
D
G
H
R
L
A
M
C
S
L
D
A
--
Q
I
P
S
-
Q
D
R
H
Q
V
I
V
P
R
K
G
I
L
E
L
A
R
L
L
T
E
Q
-
D
-
G
E
V
G
I
V
L
G
Q
-------
H
H
I
R
A
T
T
G
E
F
T
F
T
S
K
L
V
D
G
K
F
P
D
Y
E
R
V
L
P
R
G
G
D
K
L
V
V
G
D
R
Q
Q
L
R
E
A
F
S
R
T
A
I
L
S
N
E
K
-
Y
R
-
G
I
R
L
Q
L
S
-
N
-
G
L
L
K
I
Q
A
N
N
P
E
Q
E
E
A
E
E
E
V
Q
V
-
E
Y
N
G
G
N
L
E
I
G
F
N
V
S
Y
L
L
D
V
L
G
V
I
G
T
E
Q
V
R
F
I
L
S
D
S
N
S
S
A
-
L
V
H
E
A
D
---------------
N
--
D
D
S
A
Y
V
V
M
P
M
R
--
14
PsiBlast_PDB
68.17
26%
-107
- C2 -
3QSB
1
DPO3B_ECOLI
A:
[1-365]
M
K
F
T
V
E
R
E
H
L
L
K
P
L
Q
Q
V
S
G
P
L
G
G
R
P
T
L
P
I
L
G
N
L
L
L
Q
V
A
D
G
T
L
S
L
T
G
T
D
L
E
M
E
M
V
A
R
V
-------
A
L
V
Q
P
H
E
P
G
A
T
T
V
P
A
R
K
F
F
D
I
C
R
G
L
P
E
G
A
-
E
-
I
A
V
Q
L
E
G
E
R
M
-
L
-
V
R
S
G
R
S
R
F
S
L
S
T
L
P
A
A
D
F
P
N
L
D
D
W
Q
S
E
V
E
F
T
L
P
Q
A
T
M
K
R
L
I
E
A
T
Q
F
S
M
A
H
Q
D
V
R
Y
Y
L
N
G
M
L
F
E
T
-
E
G
-
E
-
E
L
R
T
V
A
T
D
G
H
R
L
A
V
C
S
M
P
I
G
Q
S
L
P
----
S
H
S
V
I
V
P
R
K
G
V
I
E
L
M
R
M
L
D
G
G
-
D
-
N
P
L
R
V
Q
I
G
S
-------
N
N
I
R
A
H
V
G
D
F
I
F
T
S
K
L
V
D
G
R
F
P
D
Y
R
R
V
L
P
K
N
P
D
K
H
L
E
A
G
C
D
L
L
K
Q
A
F
A
R
A
A
I
L
S
N
E
K
-
F
R
G
V
R
L
Y
V
S
E
---
N
Q
L
K
I
T
A
N
N
P
E
-
Q
E
E
A
E
E
I
L
D
V
T
Y
S
G
A
E
M
E
I
G
F
N
V
S
Y
V
L
D
V
L
N
A
L
K
C
E
N
V
R
M
M
L
T
D
S
V
S
S
V
-
Q
I
E
D
A
A
---------------
S
--
Q
S
A
A
Y
V
V
M
P
M
R
--
5
PsiBlast_PDB
68.01
26%
-116
- C2 -
3Q4L
1
DPO3B_ECOLI
A:
[3-367]
M
K
F
T
V
E
R
E
H
L
L
K
P
L
Q
Q
V
S
G
P
----
P
T
L
P
I
L
G
N
L
L
L
Q
V
A
D
G
T
L
S
L
T
G
T
D
L
E
M
E
M
V
A
R
V
-------
A
L
V
Q
P
H
E
P
G
A
T
T
V
P
A
R
K
F
F
D
I
C
R
G
L
P
E
G
A
-
E
-
I
A
V
Q
L
E
G
E
R
M
-
L
-
V
R
S
G
R
S
R
F
S
L
S
T
L
P
A
A
D
F
P
N
L
D
D
W
Q
S
E
V
E
F
T
L
P
Q
A
T
M
K
R
L
I
E
A
T
Q
F
S
M
A
H
Q
D
V
R
Y
Y
L
N
G
M
L
F
E
T
-
E
G
-
E
-
E
L
R
T
V
A
T
D
G
H
R
L
A
V
C
S
M
P
I
G
Q
S
L
P
----
S
H
S
V
I
V
P
R
K
G
V
I
E
L
M
R
M
L
D
G
G
-
D
-
N
P
L
R
V
Q
I
G
S
-------
N
N
I
R
A
H
V
G
D
F
I
F
T
S
K
L
V
D
G
R
F
P
D
Y
R
R
V
L
P
K
N
P
D
K
H
L
E
A
G
C
D
L
L
K
Q
A
F
A
R
A
A
I
L
S
N
E
K
-
F
R
G
V
R
L
Y
V
S
E
---
N
Q
L
K
I
T
A
N
N
P
E
-
Q
E
E
A
E
E
I
L
D
V
T
Y
S
G
A
E
M
E
I
G
F
N
V
S
Y
V
L
D
V
L
N
A
L
K
C
E
N
V
R
M
M
L
T
D
S
V
S
S
V
-
Q
I
E
D
A
A
---------------
S
--
Q
S
A
A
Y
V
V
M
P
M
R
--
10
PsiBlast_PDB
67.92
26%
-109
- C2 -
3BEP
2
DPO3B_ECOLI
A:
[1-365]
M
K
F
T
V
E
R
E
H
L
L
K
P
L
Q
Q
V
S
G
P
L
G
G
R
P
T
L
P
I
L
G
N
L
L
L
Q
V
A
D
G
T
L
S
L
T
G
T
D
L
E
M
E
M
V
A
R
V
-------
A
L
V
Q
P
H
E
P
G
A
T
T
V
P
A
R
K
F
F
D
I
C
R
G
L
P
E
G
A
-
E
-
I
A
V
Q
L
E
G
E
R
M
-
L
-
V
R
S
G
R
S
R
F
S
L
S
T
L
P
A
A
D
F
P
N
L
D
D
W
Q
S
E
V
E
F
T
L
P
Q
A
T
M
K
R
L
I
E
A
T
Q
F
S
M
A
H
Q
D
V
R
Y
Y
L
N
G
M
L
F
E
T
-
E
G
-
E
-
E
L
R
T
V
A
T
D
G
H
R
L
A
V
C
S
M
P
I
GQ
S
L
P
----
S
H
S
V
I
V
P
R
K
G
V
I
E
L
M
R
M
L
D
G
G
-
D
-
N
P
L
R
V
Q
I
G
S
-------
N
N
I
R
A
H
V
G
D
F
I
F
T
S
K
L
V
D
G
R
F
P
D
Y
R
R
V
L
P
K
N
P
D
K
H
L
E
A
G
C
D
L
L
K
Q
A
F
A
R
A
A
I
L
S
N
E
K
-
F
R
G
V
R
L
Y
V
S
E
---
N
Q
L
K
I
T
A
N
N
P
E
-
Q
E
E
A
E
E
I
L
D
V
T
Y
S
G
A
E
M
E
I
G
F
N
V
S
Y
V
L
D
V
L
N
A
L
K
C
E
N
V
R
M
M
L
T
D
S
V
S
S
V
-
Q
I
E
D
A
A
---------------
S
--
Q
S
A
A
Y
V
V
M
P
M
R
--
19
PsiBlast_PDB
67.77
26%
-109
- C2 -
4K3M
6
DPO3B_ECOLI
A:
[1-365]
M
K
F
T
V
E
R
E
H
L
L
K
P
L
Q
Q
V
S
G
-------
L
P
I
L
G
N
L
L
L
Q
V
A
D
G
T
L
S
L
T
G
T
D
L
E
M
E
M
V
A
R
V
-------
A
L
V
Q
P
H
E
P
G
A
T
T
V
P
A
R
K
F
F
D
I
C
R
G
L
P
E
G
A
-
E
-
I
A
V
Q
L
E
G
E
R
M
-
L
-
V
R
S
G
R
S
R
F
S
L
S
T
L
P
A
A
D
F
P
N
L
D
D
W
Q
S
E
V
E
F
T
L
P
Q
A
T
M
K
R
L
I
E
A
T
Q
F
S
M
A
H
Q
D
V
R
Y
Y
L
N
G
M
L
F
E
T
-
E
G
-
E
-
E
L
R
T
V
A
T
D
G
H
R
L
A
V
C
S
M
P
I
GQ
S
L
P
----
S
H
S
V
I
V
P
R
K
G
V
I
E
L
M
R
M
L
D
G
G
-
D
-
N
P
L
R
V
Q
I
G
S
-------
N
N
I
R
A
H
V
G
D
F
I
F
T
S
K
L
V
D
G
R
F
P
D
Y
R
R
V
L
P
K
N
P
D
K
H
L
E
A
G
C
D
L
L
K
Q
A
F
A
R
A
A
I
L
S
N
E
K
-
F
R
G
V
R
L
Y
V
S
E
---
N
Q
L
K
I
T
A
N
N
P
E
-
Q
E
E
A
E
E
I
L
D
V
T
Y
S
G
A
E
M
E
I
G
F
N
V
S
Y
V
L
D
V
L
N
A
L
K
C
E
N
V
R
M
M
L
T
D
S
V
S
S
V
-
Q
I
E
D
A
A
---------------
S
--
Q
S
A
A
Y
V
V
M
P
M
R
--