@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu00420: (2016-06-01 )
MNKDIATPIRTKEILKKYGFSFKKSLGQNFLIDTNILNRIVDHAEVTEKTGVIEIGPGIGALTEQLAKRAKKVVAFEIDQRLLPILKDTLSPYENVTVIHQDVLKADVKSVIEEQFQDCDEIMVVANLPYYVTTPIIMKLLEEHLPLKGIVVMLQKEVAERMAADPSSKEYGSLSIAVQFYTEAKTVMIVPKTVFVPQPNVDSAVIRLILRDGPAVDVENESFFFQLIKASFAQRRKTLLNNLVNNLPEGKAQKSTIEQVLEETNIDGKRRGESLSIEEFAALSNGLYKALF
Atome Classification :
(21 SA)
.........10........20........30........40........50-........60....-....70.........80........90-.---.---...-....100.......110.......120-.........130.......140-........150.......160.......170.......180.......190.......200.......210.-......220....---...230.......------------------240....--...250-------------------........260.---.-----...--..-------------------270--.........280.......290---
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MNKDIATP
I
R
T
K
E
I
L
K
KYG
F
S
F
K
K
S
LGQ
N
F
L
I
D
T
N
I
L
N
R
I
V
D
H
A
E
VTEKT
G
-
V
I
E
IGPG
I
G
A
L
T
E
Q
-
L
A
K
R
A
-
K
K
V
V
A
F
E
I
D
Q
R
L
L
P
I
L
K
D
TL--S---P---YE
N
-
V
T
V
I
H
Q
D
V
L
K
A
D
V
K
S
V
I
E
E
Q
F
Q
D
C
D
---
E
I
M
V
V
ANLPYYV
T
T
P
I
I
M
K
L
L
--
E
E
HLP
L
K
G
I
V
V
M
L
Q
K
E
V
A
E
R
MAADPSSKEYG
S
L
S
I
A
V
Q
F
Y
TEA
K
T
V
M
I
V
P
K
T
V
F
VPQPNV
D
S
A
V
I
R
L
I
LRDG-PAVDVEN
E
S
F
F
F
Q
---
L
I
K
A
S
F
A
Q
R
R
K
T
L
------------------
L
N
N
L
V
N
N--LPEGK--------------------
A
Q
K
S
T
I
E
Q
V
L
E
E---T-----NID--GK-------------------R----RGESL
S
I
E
E
F
A
A
L
S
N
G
L
Y
K
ALF---
8
PsiBlast_PDB
93.94
37%
-126
- C1 -
3FYC
4
RSMA_METJA
A:
[2-262]
--------------------------
A
Q
C
F
L
I
D
K
N
F
V
N
K
A
V
E
S
A
N
L
T
K
D
D
V
-
V
L
E
I
G
L
G
K
G
I
L
T
E
E
-
L
A
K
N
A
-
K
K
V
Y
V
I
E
I
D
K
S
L
E
P
Y
A
N
K
L
K
--
E
---
L
---
Y
N
N
-
I
E
I
I
W
G
D
A
L
K
V
D
L
N
K
L
--------
D
---
F
N
K
V
V
A
N
L
P
Y
Q
I
S
S
P
I
T
F
K
L
I
--
K
R
G
F
D
L
--
A
V
L
M
Y
Q
Y
E
F
A
K
R
M
V
A
K
E
G
T
K
D
Y
G
R
L
S
V
A
V
Q
S
R
A
D
V
E
I
V
A
K
V
P
P
S
A
F
Y
P
K
P
K
V
Y
S
A
I
V
K
I
K
P
N
K
G
-
K
-
Y
H
I
E
N
E
N
F
F
D
D
---
F
L
R
A
I
F
Q
H
R
N
K
S
V
------------------
R
K
A
L
I
D
S
--
S
K
E
L
N
--------------------
Y
N
K
D
E
M
K
K
I
L
E
D
F
L
N
T
-----
N
S
E
--
I
K
-------------------
N
L
I
NE
K
V
F
K
L
S
V
K
D
I
V
N
L
S
N
E
F
Y
R
F
L
----
23
PsiBlast_CBE
93.01
37%
-122
- C1 -
3FYC
5
RSMA_METJA
B:
[2-262]
--------------------------
A
Q
C
F
L
I
D
K
N
F
V
N
K
A
V
E
S
A
N
L
T
K
D
D
V
-
V
L
E
I
G
L
G
K
G
I
L
T
E
E
-
L
A
K
N
A
-
K
K
V
Y
V
I
E
I
D
K
S
L
E
P
Y
A
N
K
L
K
--
E
---
L
---
Y
N
N
-
I
E
I
I
W
G
D
A
L
K
V
D
L
N
K
L
--------
D
---
F
N
K
V
V
A
N
L
P
Y
Q
I
S
S
P
I
T
F
K
L
I
--
K
R
G
F
D
L
--
A
V
L
M
Y
Q
Y
E
F
A
K
R
M
V
A
K
E
G
T
K
D
Y
G
R
L
S
V
A
V
Q
S
R
A
D
V
E
I
V
A
K
V
P
P
S
A
F
Y
P
K
P
K
V
Y
S
A
I
V
K
I
K
P
N
K
G
-
K
-
Y
H
I
E
N
E
N
F
F
D
D
---
F
L
R
A
I
F
Q
H
R
N
K
S
V
------------------
R
K
A
L
I
D
S
--
S
K
E
L
N
--------------------
Y
N
K
D
E
M
K
K
I
L
E
D
FLN
T
-----
N
S
E
--
I
K
-------------------
N
LINE
K
V
F
K
L
S
V
K
D
I
V
N
L
S
N
E
F
Y
R
F
L
----
3
PsiBlast_PDB
92.88
37%
-122
- C1 -
3GRV
3
RSMA_METJA
A:
[30-289]
---------------------------
Q
C
F
L
I
D
K
N
F
V
N
K
A
V
E
S
A
N
L
T
K
D
D
V
-
V
L
E
I
G
L
G
K
G
I
L
T
E
E
-
L
A
K
N
A
-
K
K
V
Y
V
I
E
I
D
K
S
L
E
P
Y
A
N
K
L
K
--
E
---
L
---
Y
N
N
-
I
E
I
I
W
G
D
A
L
K
V
D
L
N
K
L
--------
D
---
F
N
K
V
V
A
N
L
P
Y
Q
I
S
S
P
I
T
F
K
L
I
--
K
R
G
F
D
L
--
A
V
L
M
Y
Q
Y
E
F
A
K
R
M
V
A
A
A
G
T
K
D
Y
G
R
L
S
V
A
V
Q
S
R
A
D
V
E
I
V
A
K
V
P
P
S
A
F
Y
P
K
P
K
V
Y
S
A
I
V
K
I
K
P
N
K
G
--
K
Y
H
I
E
N
E
N
F
F
D
D
---
F
L
R
A
I
F
Q
H
R
N
K
S
V
------------------
R
K
A
L
I
D
S
--
S
K
E
L
N
--------------------
Y
N
K
D
E
M
K
K
I
L
E
D
F
L
N
T
-----
N
S
E
--
I
K
-------------------
N
L
I
N
E
K
V
F
K
L
S
V
K
D
I
V
N
L
S
N
E
F
Y
R
F
L
----
7
PsiBlast_PDB
92.68
35%
-118
- C1 -
3FUX
1
RSMA_THET8
A:
[5-268]
-----
A
S
P
Q
S
V
R
A
L
L
E
R
H
G
L
F
A
D
K
R
F
G
Q
N
F
L
V
S
E
A
H
L
R
R
I
V
E
A
A
R
--
P
F
T
G
P
V
F
E
V
G
P
G
L
G
A
L
T
R
A
-
L
L
E
A
G
-
A
E
V
T
A
I
E
K
D
L
R
L
R
P
V
L
E
E
T
L
--
S
---
G
---
L
P
--
V
R
L
V
F
Q
D
A
L
L
Y
P
W
E
E
V
P
Q
G
S
----------
L
L
V
A
N
L
P
Y
H
I
A
T
P
L
V
T
R
L
L
--
K
T
G
R
-
F
A
R
L
V
F
L
V
Q
K
E
V
A
E
R
M
T
A
R
P
K
T
P
A
Y
G
V
L
T
L
R
V
A
H
H
A
V
A
E
R
L
F
D
L
P
P
G
A
F
F
P
P
P
K
V
W
S
S
L
V
R
L
T
------
P
T
G
A
L
D
D
P
G
L
F
R
---
L
V
E
A
A
F
G
K
R
R
K
T
L
------------------
L
N
A
L
A
A
------
A
G
--------------------
Y
P
K
A
R
V
E
E
A
L
R
A
---
L
-----
G
L
P
--
P
R
-------------------
V
----
R
A
E
E
L
D
L
E
A
F
R
R
L
R
E
G
L
E
-------
22
PsiBlast_CBE
92.51
35%
-119
- C1 -
3FUX
1
RSMA_THET8
B:
[5-268]
-----
A
S
P
Q
S
V
R
A
L
L
E
R
H
G
L
F
A
D
K
R
F
G
Q
N
F
L
V
S
E
A
H
L
R
R
I
V
E
A
A
R
--
P
F
T
G
P
V
F
E
V
G
P
G
L
G
A
L
T
R
A
-
L
L
E
A
G
-
A
E
V
T
A
I
E
K
D
L
R
L
R
P
V
L
E
E
T
L
--
S
---
G
---
L
P
--
V
R
L
V
F
Q
D
A
L
L
Y
P
W
E
E
V
P
Q
G
S
----------
L
L
V
A
N
L
P
Y
H
I
A
T
P
L
V
T
R
L
L
--
K
T
G
R
-
F
A
R
L
V
F
L
V
Q
K
E
V
A
E
R
M
T
A
R
P
K
T
P
A
Y
G
V
L
T
L
R
V
A
H
H
A
V
A
E
R
L
F
D
L
P
P
G
A
F
F
P
P
P
K
V
W
S
S
L
V
R
L
T
------
P
T
G
A
L
D
D
P
G
L
F
R
---
L
V
E
A
A
F
G
K
R
R
K
T
L
------------------
L
N
A
L
A
A
------
A
G
--------------------
Y
P
K
A
R
V
E
E
A
L
R
A
---
L
-----
G
L
P
--
P
R
-------------------
V
----
R
A
E
E
L
D
L
E
A
F
R
R
L
R
E
G
L
E
-------
49
HHSearch
92.34
38%
-115
- C1 -
3GRU
5
RSMA_METJA
A:
[30-290]
---------------------------
Q
C
F
L
I
D
K
N
F
V
N
K
A
V
E
S
A
N
L
T
K
D
D
V
-
V
L
E
I
G
L
G
K
G
I
L
T
E
E
-
L
A
K
N
A
-
K
K
V
Y
V
I
E
I
D
K
S
L
E
P
Y
A
N
K
L
K
--
E
---
L
---
Y
N
N
-
I
E
I
I
W
G
D
A
L
K
V
D
L
N
K
--------
L
D
---
F
N
K
V
V
A
N
L
P
Y
Q
I
S
S
P
I
T
F
K
L
I
--
K
R
--
G
F
D
L
A
V
L
M
Y
Q
Y
E
F
A
K
R
M
V
A
A
A
G
T
K
D
Y
G
R
L
S
V
A
V
Q
S
R
A
D
V
E
I
V
A
K
V
P
P
S
A
F
Y
P
K
P
K
V
Y
S
A
I
V
K
I
K
P
N
K
G
-
K
Y
-
H
I
E
N
E
N
F
F
D
D
---
F
L
R
A
I
F
Q
H
R
N
K
S
V
------------------
R
K
A
L
I
D
S
--
S
K
E
L
N
--------------------
Y
N
K
D
E
M
K
K
I
L
E
D
---
F
L
N
TN
S
E
I
K
N
L
I
N
-------------------
E
----
K
V
F
K
L
S
V
K
D
I
V
N
L
S
N
E
F
Y
R
F
L
Q
---
4
PsiBlast_PDB
92.22
37%
-124
- C1 -
3GRY
2
RSMA_METJA
A:
[30-289]
---------------------------
Q
C
F
L
I
D
K
N
F
V
N
K
A
V
E
S
A
N
L
T
K
D
D
V
-
V
L
E
I
G
L
G
K
G
I
L
T
E
E
-
L
A
K
N
A
-
K
K
V
Y
V
I
E
I
D
K
S
L
E
P
Y
A
N
K
L
K
--
E
---
L
---
Y
N
N
-
I
E
I
I
W
G
D
A
L
K
V
D
L
N
K
L
--------
D
---
F
N
K
V
V
A
N
L
P
Y
Q
I
S
S
P
I
T
F
K
L
I
--
K
R
G
F
D
L
--
A
V
L
M
Y
Q
Y
E
F
A
K
R
M
V
A
A
A
G
T
K
D
Y
G
R
L
S
V
A
V
Q
S
R
A
D
V
E
I
V
A
K
V
P
P
S
A
F
Y
P
K
P
K
V
Y
S
A
I
V
K
I
K
P
N
K
G
--
K
Y
H
I
E
N
E
N
F
F
D
D
---
F
L
R
A
I
F
Q
H
R
N
K
S
V
------------------
R
K
A
L
I
D
S
--
S
K
E
L
N
--------------------
Y
N
K
D
E
M
K
K
I
L
E
D
F
L
N
T
-----
N
S
E
--
I
K
-------------------
N
L
I
N
E
K
V
F
K
L
S
V
K
D
I
V
N
L
S
N
E
F
Y
R
F
L
----
2
PsiBlast_PDB
92.10
37%
-121
- C1 -
3GRU
5
RSMA_METJA
A:
[30-289]
---------------------------
Q
C
F
L
I
D
K
N
F
V
N
K
A
V
E
S
A
N
L
T
K
D
D
V
-
V
L
E
I
G
L
G
K
G
I
L
T
E
E
-
L
A
K
N
A
-
K
K
V
Y
V
I
E
I
D
K
S
L
E
P
Y
A
N
K
L
K
--
E
---
L
---
Y
N
N
-
I
E
I
I
W
G
D
A
L
K
V
D
L
N
K
L
--------
D
---
F
N
K
V
V
A
N
L
P
Y
Q
I
S
S
P
I
T
F
K
L
I
--
K
R
G
F
D
L
--
A
V
L
M
Y
Q
Y
E
F
A
K
R
M
V
A
A
A
G
T
K
D
Y
G
R
L
S
V
A
V
Q
S
R
A
D
V
E
I
V
A
K
V
P
P
S
A
F
Y
P
K
P
K
V
Y
S
A
I
V
K
I
K
P
N
K
G
--
K
Y
H
I
E
N
E
N
F
F
D
D
---
F
L
R
A
I
F
Q
H
R
N
K
S
V
------------------
R
K
A
L
I
D
S
--
S
K
E
L
N
--------------------
Y
N
K
D
E
M
K
K
I
L
E
D
F
L
N
T
-----
N
S
E
--
I
K
-------------------
N
L
I
N
E
K
V
F
K
L
S
V
K
D
I
V
N
L
S
N
E
F
Y
R
F
L
----
9
PsiBlast_PDB
91.79
37%
-121
- C1 -
3FYD
5
RSMA_METJA
A:
[1-260]
---------------------------
Q
C
F
L
I
D
K
N
F
V
N
K
A
V
E
S
A
N
L
T
K
D
D
V
-
V
L
E
I
G
L
G
K
G
I
L
T
E
E
-
L
A
K
N
A
-
K
K
V
Y
V
I
E
I
D
K
S
L
E
P
Y
A
N
K
L
K
--
E
---
L
---
Y
N
N
-
I
E
I
I
W
G
D
A
L
K
V
D
L
N
K
L
--------
D
---
F
N
K
V
V
A
N
L
P
Y
Q
I
S
S
P
I
T
F
K
L
I
--
K
R
G
F
D
L
--
A
V
L
M
Y
Q
Y
E
F
A
K
R
M
V
A
A
A
G
T
K
D
Y
G
R
L
S
V
A
V
Q
S
R
A
D
V
E
I
V
A
K
V
P
P
S
A
F
Y
P
K
P
K
V
Y
S
A
I
V
K
I
K
P
N
K
G
-
K
-
Y
H
I
E
N
E
N
F
F
D
D
---
F
L
R
A
I
F
Q
H
R
N
K
S
V
------------------
R
K
A
L
I
D
S
--
S
K
E
L
N
--------------------
Y
N
K
D
E
M
K
K
I
L
E
D
F
L
N
T
-----
N
S
E
--
I
K
-------------------
N
L
I
N
E
K
V
F
K
L
S
V
K
D
I
V
N
L
S
N
E
F
Y
R
F
L
----
1
PsiBlast_PDB
91.36
37%
-118
- C1 -
3GRR
1
RSMA_METJA
A:
[30-289]
---------------------------
Q
C
F
L
I
D
K
N
F
V
N
K
A
V
E
S
A
N
L
T
K
D
D
V
-
V
L
E
I
G
L
G
K
G
I
L
T
E
E
-
L
A
K
N
A
-
K
K
V
Y
V
I
E
I
D
K
S
L
E
P
Y
A
N
K
L
K
--
E
---
L
---
Y
N
N
-
I
E
I
I
W
G
D
A
L
K
V
D
L
N
K
L
--------
D
---
F
N
K
V
V
A
N
L
P
Y
Q
I
S
S
P
I
T
F
K
L
I
--
K
R
G
F
D
L
--
A
V
L
M
Y
Q
Y
E
F
A
K
R
M
V
A
A
A
G
T
K
D
Y
G
R
L
S
V
A
V
Q
S
R
A
D
V
E
I
V
A
K
V
P
P
S
A
F
Y
P
K
P
K
V
Y
S
A
I
V
K
I
K
P
N
K
G
--
K
Y
H
I
E
N
E
N
F
F
D
D
---
F
L
R
A
I
F
Q
H
R
N
K
S
V
------------------
R
K
A
L
I
D
S
--
S
K
E
L
N
--------------------
Y
N
K
D
E
M
K
K
I
L
E
D
F
L
N
T
-----
N
S
E
--
I
K
-------------------
N
L
I
N
E
K
V
F
K
L
S
V
K
D
I
V
N
L
S
N
E
F
Y
R
F
L
----
21
PsiBlast_CBE
91.00
35%
-120
- C1 -
3FUX
1
RSMA_THET8
C:
[4-268]
----
L
A
S
P
Q
S
V
R
A
L
L
E
R
H
G
L
F
A
D
K
R
F
G
Q
N
F
L
V
S
E
A
H
L
R
R
I
V
E
A
A
R
--
P
F
T
G
P
V
F
E
V
G
P
G
L
G
A
L
T
R
A
-
L
L
E
A
G
-
A
E
V
T
A
I
E
K
D
L
R
L
R
P
V
L
E
E
T
L
--
S
---
G
---
L
P
--
V
R
L
V
F
Q
D
A
L
L
Y
P
W
E
E
V
P
Q
G
S
----------
L
L
V
A
N
L
P
Y
H
I
A
T
P
L
V
T
R
L
L
--
K
T
G
R
-
F
A
R
L
V
F
L
V
Q
K
E
V
A
E
R
M
T
A
R
P
K
T
P
A
Y
G
V
L
T
L
R
V
A
H
H
A
V
A
E
R
L
F
D
L
P
P
G
A
F
F
P
P
P
K
V
W
S
S
L
V
R
L
T
------
P
T
G
A
L
D
D
P
G
L
F
R
---
L
V
E
A
A
F
G
K
R
R
K
T
L
------------------
L
N
A
L
A
A
------
A
G
--------------------
Y
P
K
A
R
V
E
E
A
L
R
A
---
L
-----
G
L
P
--
P
R
-------------------
V
----
R
A
E
E
L
D
L
E
A
F
R
R
L
R
E
G
L
E
-------
6
PsiBlast_PDB
90.93
35%
-117
- C1 -
3FUW
1
RSMA_THET8
A:
[6-268]
------
S
P
Q
S
V
R
A
L
L
E
R
H
G
L
F
A
D
K
R
F
G
Q
N
F
L
V
S
E
A
H
L
R
R
I
V
E
A
A
R
--
P
F
T
G
P
V
F
E
V
G
P
G
L
G
A
L
T
R
A
-
L
L
E
A
G
-
A
E
V
T
A
I
E
K
D
L
R
L
R
P
V
L
E
E
T
L
--
S
---
G
---
L
P
--
V
R
L
V
F
Q
D
A
L
L
Y
P
W
E
E
V
P
Q
G
S
----------
L
L
V
A
N
L
P
Y
H
I
A
T
P
L
V
T
R
L
L
--
K
T
G
R
-
F
A
R
L
V
F
L
V
Q
K
E
V
A
E
R
M
T
A
R
P
K
T
P
A
Y
G
V
L
T
L
R
V
A
H
H
A
V
A
E
R
L
F
D
L
P
P
G
A
F
F
P
P
P
K
V
W
S
S
L
V
R
L
T
------
P
T
G
A
L
D
D
P
G
L
F
R
---
L
V
E
A
A
F
G
K
R
R
K
T
L
------------------
L
N
A
L
A
A
------
A
G
--------------------
Y
P
K
A
R
V
E
E
A
L
R
A
---
L
-----
G
L
P
--
P
R
-------------------
V
----
R
A
E
E
L
D
L
E
A
F
R
R
L
R
E
G
L
E
-------
25
PsiBlast_CBE
90.83
31%
-116
- C1 -
1ZQ9
1
DIM1_HUMAN
B:
[8-277]
---------------------------
Q
H
I
L
K
N
P
L
I
I
N
S
I
I
D
K
A
A
L
R
P
T
D
V
-
V
L
E
V
G
P
G
T
G
N
M
T
V
K
-
L
L
E
K
A
-
K
K
V
V
A
C
E
L
D
P
R
L
V
A
E
L
H
K
R
V
QG
T
---
P
---
V
A
S
K
L
Q
V
L
V
G
D
V
L
K
T
D
L
P
F
-----
F
D
T
C
--------
V
A
N
L
P
Y
Q
I
S
S
P
F
V
F
K
L
L
--
L
H
R
P
F
F
R
C
A
I
L
M
F
Q
R
E
F
A
L
R
L
V
A
K
P
G
D
K
L
Y
C
R
L
S
I
N
T
Q
L
L
A
R
V
D
H
L
M
K
V
G
K
N
N
F
R
P
P
P
K
V
E
S
S
V
V
R
I
E
P
K
N
P
-
P
P
--
P
I
N
F
Q
E
W
D
G
---
L
V
R
I
T
F
V
R
K
N
K
T
L
SAAFKSSAVQQLLEKNYR
I
H
C
S
V
H
N
II
I
P
E
D
F
--------------------
S
I
A
D
K
I
Q
Q
I
L
T
S
---
T
-----
G
F
S
--
D
K
------------------------
R
A
R
S
M
D
I
D
D
F
I
R
L
L
H
G
F
--------
16
PsiBlast_PDB
90.80
31%
-117
- C1 -
1ZQ9
1
DIM1_HUMAN
A:
[8-277]
---------------------------
Q
H
I
L
K
N
P
L
I
I
N
S
I
I
D
K
A
A
L
R
P
T
D
V
-
V
L
E
V
G
P
G
T
G
N
M
T
V
K
-
L
L
E
K
A
-
K
K
V
V
A
C
E
L
D
P
R
L
V
A
E
L
H
K
R
V
QG
T
---
P
---
V
A
S
K
L
Q
V
L
V
G
D
V
L
K
T
D
L
P
F
-----
F
D
T
C
--------
V
A
N
L
P
Y
Q
I
S
S
P
F
V
F
K
L
L
--
L
H
R
P
F
F
R
C
A
I
L
M
F
Q
R
E
F
A
L
R
L
V
A
K
P
G
D
K
L
Y
C
R
L
S
I
N
T
Q
L
L
A
R
V
D
H
L
M
K
V
G
K
N
N
F
R
P
P
P
K
V
E
S
S
V
V
R
I
E
P
K
N
P
-
P
P
--
P
I
N
F
Q
E
W
D
G
---
L
V
R
I
T
F
V
R
K
N
K
T
L
S
A
A
F
K
S
S
A
V
Q
Q
L
L
E
K
N
Y
R
I
H
C
S
V
H
N
I
I
I
P
E
D
F
--------------------
S
I
A
D
K
I
Q
Q
I
L
T
S
---
T
-----
G
F
S
--
D
K
------------------------
R
A
R
S
M
D
I
D
D
F
I
R
L
L
H
G
F
--------
5
PsiBlast_PDB
90.19
35%
-118
- C1 -
3FUU
1
RSMA_THET8
A:
[6-268]
------
S
P
Q
S
V
R
A
L
L
E
R
H
G
L
F
A
D
K
R
F
G
Q
N
F
L
V
S
E
A
H
L
R
R
I
V
E
A
A
R
--
P
F
T
G
P
V
F
E
V
G
P
G
L
G
A
L
T
R
A
-
L
L
E
A
G
-
A
E
V
T
A
I
E
K
D
L
R
L
R
P
V
L
E
E
T
L
--
S
---
G
---
L
P
--
V
R
L
V
F
Q
D
A
L
L
Y
P
W
E
E
V
P
Q
G
S
----------
L
L
V
A
N
L
P
Y
H
I
A
T
P
L
V
T
R
L
L
--
K
T
G
R
-
F
A
R
L
V
F
L
V
Q
K
E
V
A
E
R
M
T
A
R
P
K
T
P
A
Y
G
V
L
T
L
R
V
A
H
H
A
V
A
E
R
L
F
D
L
P
P
G
A
F
F
P
P
P
K
V
W
S
S
L
V
R
L
T
------
P
T
G
A
L
D
D
P
G
L
F
R
---
L
V
E
A
A
F
G
K
R
R
K
T
L
------------------
L
N
A
L
A
A
------
A
G
--------------------
Y
P
K
A
R
V
E
E
A
L
R
A
---
L
-----
G
L
P
--
P
R
-------------------
V
----
R
A
E
E
L
D
L
E
A
F
R
R
L
R
E
G
L
E
-------
50
HHSearch
89.51
33%
-113
* C1 *
1ZQ9
1
DIM1_HUMAN
A:
[8-279]
---------------------------
Q
H
I
L
K
N
P
L
I
I
N
S
I
I
D
K
A
A
L
R
P
T
D
V
-
V
L
E
V
G
P
G
T
G
N
M
T
V
K
-
L
L
E
K
A
-
K
K
V
V
A
C
E
L
D
P
R
L
V
A
E
L
H
K
R
V
--
Q
---
G
TPV
A
S
K
-
L
Q
V
L
V
G
D
V
L
K
T
D
L
----------
P
F
---
F
D
T
C
V
A
N
L
P
Y
Q
I
S
S
P
F
V
F
K
L
L
--
L
H
R
P
F
F
R
C
A
I
L
M
F
Q
R
E
F
A
L
R
L
V
A
K
P
G
D
K
L
Y
C
R
L
S
I
N
T
Q
L
L
A
R
V
D
H
L
M
K
V
G
K
N
N
F
R
P
P
P
K
V
E
S
S
V
V
R
I
E
P
K
N
P
-
P
P
--
P
I
N
F
Q
E
W
D
G
---
L
V
R
I
T
F
V
R
K
N
K
T
L
------------------
S
A
A
F
K
S
S
--
A
V
Q
Q
L
L
E
K
N
Y
R
I
H
C
S
V
H
N
I
I
I
P
EDF
S
I
A
D
K
I
Q
Q
I
L
T
S
---
T
-----
G
F
S
---
D
-------------------
K
----
R
A
R
S
M
D
I
D
D
F
I
R
L
L
H
G
F
N
A
------
33
Fugue
86.87
31%
-115
- C1 -
1ZQ9
1
DIM1_HUMAN
A:
[8-285]
---------------------------
Q
H
I
L
K
N
P
L
I
I
N
S
I
I
D
K
A
A
L
R
P
T
D
V
-
V
L
E
V
G
P
G
T
G
N
M
T
V
K
-
L
L
E
K
A
-
K
K
V
V
A
C
E
L
D
P
R
L
V
A
E
L
H
K
R
V
--
Q
GTP
V
---
A
S
K
-
L
Q
V
L
V
G
D
V
L
K
T
D
L
P
F
F
D
-------------
T
C
V
A
N
L
P
Y
Q
I
S
S
P
F
V
F
K
L
L
--
L
H
R
P
F
F
R
C
A
I
L
M
F
Q
R
E
F
A
L
R
L
V
A
K
P
G
D
K
L
Y
C
R
L
S
I
N
T
Q
L
L
A
R
V
D
H
L
M
K
V
G
K
N
N
F
R
P
P
P
K
V
E
S
S
V
V
R
I
E
P
K
N
P
-
P
--
P
P
I
N
F
Q
E
W
D
G
---
L
V
R
I
T
F
V
R
K
N
K
T
L
------------------
S
A
A
F
K
S
S
--
A
V
Q
Q
L
--------------------
L
E
K
N
Y
R
I
H
C
S
V
H
---
N
-----
I
I
I
--
P
E
DFS
I
A
D
K
I
Q
Q
I
L
T
S
T
GFSD
K
----
R
A
R
S
M
D
I
D
D
F
I
R
L
L
H
G
F
N
A
E
G
I
HFS
11
PsiBlast_PDB
85.82
31%
-126
- C1 -
4JXJ
11
RSMA_RICBR
A:
[31-274]
----------------------------
N
F
I
F
D
G
S
L
C
D
K
I
V
R
A
S
G
L
E
E
N
S
N
-
V
L
E
I
G
P
G
T
G
G
L
T
R
S
I
L
H
K
N
P
-
K
L
L
T
V
I
E
T
D
E
R
C
I
P
L
L
N
E
I
K
--
Q
---
Y
---
H
P
N
-
L
N
I
I
K
Q
D
A
L
K
L
K
L
S
D
L
------
N
T
N
---
K
I
T
I
I
S
N
L
P
Y
H
I
G
T
E
L
V
I
R
W
L
--
K
E
S
S
L
V
A
S
M
T
L
M
L
Q
K
E
V
V
E
R
I
C
A
K
P
S
T
K
A
Y
G
R
L
S
V
I
C
S
L
I
A
T
V
E
K
C
F
D
V
A
P
T
A
F
Y
P
P
P
K
V
Y
S
A
I
V
K
L
T
-----
P
L
E
N
I
P
N
S
D
L
I
S
K
V
E
L
I
T
K
M
A
F
A
G
R
R
K
M
I
------------------
K
S
S
L
K
N
L
--
A
P
N
---------------------------
I
S
E
L
L
A
K
---
L
-----
N
I
S
--
D
N
-------------------
C
----
R
A
E
N
L
T
P
N
D
Y
L
S
L
A
S
----------
14
PsiBlast_PDB
84.88
32%
-119
- C1 -
4ADV
-
RSMA_ECOLI
V:
[17-264]
---------------------------
Q
N
F
L
N
D
Q
F
V
I
D
S
I
V
S
A
I
N
P
Q
K
G
Q
A
-
M
V
E
I
G
P
G
L
A
A
L
T
E
P
-
V
G
E
R
L
-
D
Q
L
T
V
I
E
L
D
R
D
L
A
A
R
L
Q
T
H
P
--
F
---
L
---
G
P
K
-
L
T
I
Y
Q
Q
D
A
M
T
F
N
F
G
E
L
A
E
K
M
G
Q
------
P
L
R
V
F
G
N
L
P
Y
N
I
S
T
P
L
M
F
H
L
F
--
S
Y
T
D
A
I
A
D
M
H
F
M
L
Q
K
E
V
V
N
R
L
V
A
G
P
N
S
K
A
Y
G
R
L
S
V
M
A
Q
Y
Y
C
N
V
I
P
V
L
E
V
P
P
S
A
F
T
P
P
P
K
V
D
S
A
V
V
R
L
V
P
H
A
T
-
M
P
H
P
V
K
D
V
R
V
L
S
R
---
I
T
T
E
A
F
N
Q
R
R
K
T
I
------------------
R
N
S
L
G
N
L
--
F
----------------------------
S
V
E
-
V
L
T
G
---
M
-----
G
I
D
--
P
A
-------------------
M
----
R
A
E
N
I
S
V
A
Q
Y
C
Q
M
A
N
Y
L
--------
13
PsiBlast_PDB
84.47
32%
-119
- C1 -
1QYR
-
RSMA_ECOLI
A:
[17-264]
---------------------------
Q
N
F
L
N
D
Q
F
V
I
D
S
I
V
S
A
I
N
P
Q
K
G
Q
A
-
M
V
E
I
G
P
G
L
A
A
L
T
E
P
-
V
G
E
R
L
-
D
Q
L
T
V
I
E
L
D
R
D
L
A
A
R
L
Q
T
H
P
--
F
---
L
---
G
P
K
-
L
T
I
Y
Q
Q
D
A
M
T
F
N
F
G
E
L
A
E
K
M
G
Q
------
P
L
R
V
F
G
N
L
P
Y
N
I
S
T
P
L
M
F
H
L
F
--
S
Y
T
D
A
I
A
D
M
H
F
M
L
Q
K
E
V
V
N
R
L
V
A
G
P
N
S
K
A
Y
G
R
L
S
V
M
A
Q
Y
Y
C
N
V
I
P
V
L
E
V
P
P
S
A
F
T
P
P
P
K
V
D
S
A
V
V
R
L
V
P
H
A
T
-
M
P
H
P
V
K
D
V
R
V
L
S
R
---
I
T
T
E
A
F
N
Q
R
R
K
T
I
------------------
R
N
S
L
G
N
L
--
F
----------------------------
S
V
E
-
V
L
T
G
---
M
-----
G
I
D
--
P
A
-------------------
M
----
R
A
E
N
I
S
V
A
Q
Y
C
Q
M
A
N
Y
L
--------
27
PsiBlast_CBE
77.19
33%
-123
- C1 -
3FTF
3
RSMA_AQUAE
A:
[5-240]
---------------------
L
K
K
S
F
G
Q
H
L
L
V
S
E
G
V
L
K
K
I
A
E
E
L
N
I
E
E
G
N
T
-
V
V
E
V
G
G
G
T
G
N
L
T
K
V
-
L
L
Q
H
P
L
K
K
L
Y
V
I
E
L
D
R
E
M
V
E
N
L
K
S
I
G
--
D
--------
E
R
-
L
E
V
I
N
E
D
A
S
K
----------
F
P
F
C
S
LGK
E
L
K
V
V
G
N
L
P
Y
N
V
A
S
L
I
I
E
N
T
V
Y
N
K
D
C
V
P
L
--
A
V
F
M
V
Q
K
E
V
A
E
K
L
Q
G
---
K
K
D
T
G
W
L
S
V
F
V
R
T
F
Y
D
V
N
Y
V
M
T
V
P
P
R
F
F
V
P
P
P
K
V
Q
S
A
V
I
K
L
V
K
N
E
K
F
P
V
K
D
L
K
N
Y
K
K
F
L
T
---
K
I
---
F
Q
N
R
R
K
V
L
-----------------------------------------------------
R
K
K
I
P
E
E
L
L
K
E
---
A
-----
G
I
N
--
P
D
-------------------
A
----
R
V
E
Q
L
S
L
E
D
F
F
K
L
------------