@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu00720: (2016-06-02 )
MKSRTIWTIILGALLVCCIAVAYTLTKSQAGASSSGESIATIGGKSVTREEWLKEMEDQYGKSTLEDMINVRVVEQLAKKNKLKISKSEVDREFLLIKAVNNSFYEDEHTTEKEWKDQIRYNILLEDLLTRDIDISNKELESFYNKNKELYQFDDSYRIRHIVVKDEEEAREVLKELKGGSSFEAVAAERSTDRYTSPYGGDLGFVTEASDNIPSAYIEEAKTLKEDEWSQEPIKVSNGYAIIQLKEKLKARTFSFDEVKDQIRRQIAMDQLGDKATVKTLWKEADVSWFYGEKSTK
Atome Classification :
(20 SA)
.........10........20........30.....--...40.......------------.50.......----------------.60........70........80........90........-100-------..-------..------..-.----..110-----...-----..-.---...120....------..----.130--.---........140.......150.......160..------------.------------...---------------------.170.....------------------------------------------------------------------------------------------------------------.------.------180........190....--...200..-.--...-.210..---......220.......230---.......-..240.....-..250-.......260.......270.--...----.--..280.......290.....-------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MKSR
T
I
W
T
I
I
L
G
A
L
L
V
C
C
I
A
V
A
Y
T
L
TKSQAGASSSG--E
S
I
A
TIGGKSV
T
------------
R
E
E
W
L
K
E
M
E
D
----------------QY
G
K
S
T
L
E
D
M
I
N
V
R
V
V
E
Q
L
A
K
KNKLKI
S
K
SEVDR
E
F
L
L
I
K
A-V---------NN-------SF------YE-D----EHT-------
T
E
K
-----
E
W
-
K
---
D
Q
I
R
Y
N
I
L
L
E
------
D
L
----
L
T----R---DIDI
S
N
K
E
L
E
S
F
Y
NKN
K
E
L
YQFDDSY
R
I
R
H
I
V
V------------K------------
D
E
E
---------------------
E
A
R
E
V
L
K
E
L------------------------------------------------------------------------------------------------------------K------G------G-SS
F
E
A
V
A
AERSTDRYT--SPYGGDL
G
-
F
--
V
TE-AS-DNI---
P
S
A
Y
I
E
E
A
K
TLKEDEWS-----QE
P
I
K
VS-N
G
Y
A
I
I
Q
L
K
E
-KLKAR-TF
S
F
D
E
V
K
D
Q
I
R
R
Q
I
A
M
D
QLG--
D
K
A
----
T
--
V
K
T
L
W
K
EAD
V
S
W
F
YGEKSTK-------------------------------------------------------------------------------------------------
26
HHSearch
88.89
27%
-60
- C3 -
3RFW
-
CBF2_CAMJE
A:
[22-273]
--------------------------------------
A
T
V
A
T
V
N
G
K
S
I
S
------------
D
T
E
V
S
E
F
F
A
P
MLRGQDFKTLP
D
----
N
Q
K
K
A
L
I
Q
Q
Y
I
M
Q
D
L
I
L
Q
D
A
K
K
Q
N
L
E
K
D
P
L
-
Y
T
K
E
L
D
R
A
-----------------------------------------------------------
K
---
D
A
I
L
V
N
V
Y
Q
E
------
K
I
-----
L
----
N
---
T
I
K
I
D
A
A
K
V
K
A
F
Y
D
Q
N
K
D
K
Y
V
K
P
A
R
V
Q
A
K
H
I
L
V
------------
A
------------
T
E
K
---------------------
E
A
K
D
I
I
N
E
L
------------------------------------------------------------------------------------------------------------
K
------
G
LKG
K
E
L
D
-
A
K
F
S
E
L
A
K
E
K
S
I
D
P
G
S
--
K
N
Q
G
G
E
L
G
-
W
--
F
D
Q
-
S
---
T
M
---
V
K
P
F
T
D
A
A
F
A
L
K
N
G
T
I
T
-----
T
T
P
V
K
T
N
-
F
G
Y
H
V
I
L
K
E
N
-
S
Q
A
K
G
-
Q
I
K
F
D
E
V
K
Q
G
I
E
N
G
L
K
F
E
E
F
K
--
K
V
I
----
N
Q
K
G
Q
D
L
L
N
S
A
K
V
E
Y
K
--------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
84.71
26%
-63
- C3 -
3RFW
-
CBF2_CAMJE
A:
[23-253]
---------------------------------------
T
V
A
T
V
N
G
K
S
I
S
D
T
E
V
S
E
F
F
A
PML
R
G
Q
D
F
K
T
L
P
D
----------------
N
Q
K
K
A
L
I
Q
Q
Y
I
M
Q
D
L
I
L
Q
D
A
K
K
Q
N
L
-------
E
K
D
P
L
Y
T
K
E
-
L
---------
D
R
-------
A
------------------------------------
K
---
D
A
I
L
V
N
V
Y
Q
E
------
K
I
----
L
N
----
T
----
I
K
I
D
A
A
K
V
K
A
F
Y
D
Q
N
K
D
K
Y
V
K
P
A
R
V
Q
A
K
H
I
L
V
------------
A
------------
T
E
K
---------------------
E
A
K
D
I
I
N
E
L
------------------------------------------------------------------------------------------------------------
K
------
G
LKG
K
E
L
D
-
A
K
F
S
E
L
A
K
E
K
S
I
D
P
G
S
--
K
N
Q
G
G
E
L
G
-
W
--
F
D
Q
-
S
T
-
M
V
K
---
P
--
F
T
D
A
A
F
A
L
K
N
G
T
I
T
-----
T
T
P
V
K
T
N
-
F
G
Y
H
V
I
-
L
K
E
-
N
S
Q
A
K
G
Q
I
K
F
D
E
V
K
Q
G
I
E
N
G
L
K
F
E
E
F
----------------------------------------------------------------------------------------------------------------------------------
43
Fugue
81.04
22%
-45
- C3 -
3RFW
-
CBF2_CAMJE
A:
[22-273]
--------------------------------------
A
T
V
A
T
V
N
G
K
S
I
S
------------
D
T
E
V
S
E
F
F
A
P
----------------
M
L
R
G
Q
D
---------
F
K
T
L
P
D
N
Q
K
K
A
L
I
Q
Q
Y
I
M
Q
D
L
I
L
Q
D
A
-
K
---------
K
Q
-------
N
L
------
E
K
D
P
----
L
Y
T
-------
K
E
L
-----
D
R
-
A
---
K
D
A
I
L
V
N
V
Y
Q
------
E
K
----
I
L
----
N
---
T
I
K
I
D
A
A
K
V
K
A
F
Y
D
Q
N
K
D
K
Y
V
K
P
A
R
V
Q
A
K
H
I
L
V
------------
A
------------
T
E
K
---------------------
E
A
K
D
I
I
N
E
L
------------------------------------------------------------------------------------------------------------
K
------
G
LKG
K
E
L
D
-
A
K
F
S
E
L
A
K
E
K
S
I
D
P
G
S
--
K
N
Q
G
G
E
L
G
-
W
--
F
D
Q
----
S
T
M
---
V
K
P
F
T
D
A
A
F
A
L
K
N
G
T
I
T
-----
T
T
P
V
K
T
N
-
F
G
Y
H
V
I
L
K
E
N
-
S
Q
A
K
G
-
Q
I
K
F
D
E
V
K
Q
G
I
E
N
G
L
K
F
E
E
F
K
--
K
V
I
----
N
--
Q
K
G
Q
D
L
L
N
S
-----
A
K
V
E
Y
K
-------------------------------------------------------------------------------------------------
22
HHSearch
79.89
20%
-47
- C3 -
3NRK
-
?
A:
[50-347]
----------------------------------
L
N
--
R
V
I
A
T
V
G
T
V
S
I
S
------------
E
L
D
L
D
D
A
T
E
K
Y
N
R
L
Q
KHLKHEDYRK-
S
F
R
T
R
I
I
D
F
L
I
D
R
A
I
V
D
V
V
A
E
E
E
S
I
Q
V
N
E
Q
R
V
D
S
E
I
E
K
R
M
E
-
V
---------
M
G
IT-----
N
R
K
Q
F
E
K
T
M
E
-
T
S
---
S
G
M
-------
P
F
E
-----
L
W
-
V
---
T
E
L
P
Y
Q
I
K
K
G
------
Q
L
----
L
Q
L
K
I
-
A
---
V
P
P
P
N
E
Q
E
I
R
S
W
Y
N
Q
N
K
D
K
V
--
G
F
E
I
R
Y
R
I
I
S
I
------------
A
------------
P
E
N
DS
I
Q
E
E
N
R
L
Y
K
----------
E
V
S
E
I
R
K
S
I
------------------------------------------------------------------------------------------------------------
L
A
-----
D
------
P
-
S
S
F
A
L
I
A
G
S
P
R
N
D
P
A
L
--
R
A
R
R
G
M
V
E
-
W
--
I
S
S
-
F
---
D
L
Y
K
Y
S
K
I
T
A
T
I
A
A
P
L
P
N
G
G
V
S
------
E
V
F
R
D
E
R
K
R
Y
C
I
L
K
I
E
G
-
K
R
P
----
T
P
M
E
N
L
R
G
G
I
Q
N
I
L
Y
R
D
K
E
E
--
D
T
F
----
H
R
W
L
K
E
S
R
A
E
I
P
I
Q
I
F
D
E
A
Y
R
---------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
77.61
25%
-45
- C3 -
5HTF
2
?
A:
[2-215]
-------------------------------
A
C
G
S
S
--
A
V
I
K
T
D
A
G
-
S
V
T
------------
Q
D
E
L
Y
E
A
M
K
T
----------------
T
Y
G
N
E
V
V
Q
Q
L
T
F
K
K
I
L
E
-----
D
K
Y
T
V
T
E
K
E
V
N
A
E
Y
K
K
Y
E
E
-
Q
---------
Y
G
-------
D
S
------
F
E
-
S
T
L
S
S
N
N
L
-------
T
K
T
-----
S
F
-
K
---
E
N
L
E
Y
N
L
L
V
Q
------
K
A
----
T
E
----
A
---
N
M
D
V
S
E
S
K
L
K
A
Y
Y
K
------
T
W
E
P
D
I
T
V
R
H
I
L
V
------------
D
------------
D
E
A
---------------------
T
A
K
E
I
Q
T
K
L
------------------------------------------------------------------------------------------------------------
K
------
N
------
G
-
E
K
F
T
D
L
A
K
E
Y
S
T
D
T
A
T
--
S
T
N
G
G
L
L
D
-
P
--
F
---
G
P
-
G
E
M
---
D
E
T
F
E
K
A
A
Y
A
L
E
N
K
D
D
V
-----
S
G
I
V
K
S
T
-
Y
G
Y
H
L
I
Q
L
V
K
-
K
T
E
K
G
-
T
Y
A
---------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
77.49
22%
-57
- C3 -
1M5Y
-
SURA_ECOLI
A:
[25-427]
----------------------------------
V
D
--
K
V
A
A
V
V
N
N
G
V
V
L
------------
E
S
D
V
D
G
L
M
Q
S
V
K
L
N
A
A
Q
A
R
Q
Q
L
P
D
D
A
T
L
R
H
Q
I
M
E
R
L
I
M
D
Q
I
I
L
Q
M
G
Q
K
M
G
V
K
I
S
D
E
Q
L
D
Q
A
I
A
N
I
A
K
-
Q
---------
N
N
M------
T
L
D
Q
M
R
S
R
L
A
-
Y
----
D
G
L
-------
N
Y
N
-----
T
Y
-
R
---
N
Q
I
R
K
E
M
I
I
S
------
E
V
----
R
N
N
E
V
R
R
---
R
I
T
I
L
P
Q
E
V
E
S
L
A
Q
Q
V
-------
T
E
L
N
L
S
H
I
L
I
------------
P
------------
L
P
E
NPT
S
D
Q
V
N
E
A
E
S
---------
Q
A
R
A
I
V
D
Q
A
R
N
GAD
F
G
K
L
A
I
A
HSADQQALNGGQMGWGRIQELPGIF
A
Q
A
L
S
T
AKKGDIV
G
P
I
R
S
GV
G
F
H
I
L
K
VN
D
L
R
G
E
SKNIS
V
T
E
V
H
A
R
H
I
L
L
K
P
SPIMT
D
E
Q
A
R
V
K
L
E
Q
I
A
A
D
I
K
------
S
------
G
K
T
T
F
A
A
A
A
K
E
F
S
Q
D
P
G
S
--
A
N
Q
G
G
D
L
G
-
W
--
A
T
P
-
D
---
I
F
---
D
P
A
F
R
D
A
L
T
R
L
N
K
G
Q
M
S
------
A
P
V
H
S
S
-
F
G
W
H
L
I
E
L
L
D
-
T
R
N
V
D
----------
R
A
Y
R
M
L
M
N
R
K
F
S
--
E
E
A
----
A
S
W
M
Q
E
Q
R
A
S
A
Y
V
K
I
L
S
-------------------------------------------------------------------------------------------------------
24
HHSearch
77.14
24%
-41
- C3 -
5EZ1
1
?
A:
[24-266]
-------------------------------------------------
T
------------
K
S
D
F
D
M
I
K
--E---------------
K
E
K
E
A
L
I
D
Q
A
I
R
T
A
L
V
E
N
E
A
K
T
E
K
L
D
S
T
P
E
-
F
K
A
M
M
E
A
V
K
--------------------------------------------------------------
K
Q
A
L
V
E
F
W
A
K
------
K
Q
A
E
--
E
V
----
K
---
K
V
Q
I
P
E
K
E
M
Q
D
F
Y
N
A
N
K
D
Q
L
F
V
K
Q
E
A
H
A
R
H
I
L
V
------------
K
------------
T
E
D
---------------------
E
A
K
R
I
I
S
E
I
------------------------------------------------------------------------------------------------------------
D
K
QPKAK
K
------
E
-
A
K
F
I
E
L
A
N
R
D
T
I
D
P
N
S
K
N
A
Q
N
G
G
D
L
G
-
K
--
F
Q
K
-
N
---
Q
M
---
A
P
D
F
S
K
A
A
F
A
L
T
P
G
D
Y
T
-----
K
T
P
V
K
T
E
-
F
G
Y
H
I
I
Y
L
I
S
-
K
D
S
P
V
-
T
Y
T
Y
E
Q
A
K
P
T
I
K
G
M
L
Q
E
K
L
F
Q
--
E
R
M
----
N
Q
R
I
E
E
L
R
K
H
A
K
I
V
----------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
74.61
19%
-54
- C3 -
1M5Y
-
SURA_ECOLI
A:
[71-293]
----------------------------------------------------------------------------------------------
M
E
R
L
I
M
D
Q
I
I
L
Q
M
G
Q
K
M
G
V
K
I
S
D
E
Q
L
D
Q
A
I
A
N
I
A
K
-
Q
---------
N
N
-------
M
T
------
L
D
-
Q
----
M
R
S
R
L
A
Y
D
GL
N
Y
N
-----
T
Y
-
R
---
N
Q
I
R
K
E
M
I
I
S
------
E
V
R
N
N
E
V
R
----
R
---
R
I
T
I
L
P
Q
E
V
E
S
L
A
Q
Q
V
-------
T
E
L
N
L
S
H
I
L
I
------------
P
LPENPT
S
D
Q
V
N
E
A
E
S
---------------------
Q
A
R
A
I
V
D
Q
A
------------------------------------------------------------------------------------------------------------
R
------
N
------
G
-
A
D
F
G
K
L
A
I
A
H
S
A
D
Q
Q
A
--
L
-
N
G
G
Q
M
G
-
W
GR
I
Q
E
------
L
---
P
G
I
F
A
Q
A
L
S
T
A
K
K
G
D
I
V
------
G
P
I
R
S
G
-
V
G
F
H
I
L
K
V
N
D
L
R
G
E
S
K
-
N
I
S
V
T
E
V
-----------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
73.48
19%
-51
- C3 -
2PV3
1
SURA_ECOLI
A:
[51-260]
----------------------------------------------------------------------------------------------
M
E
R
L
I
M
D
Q
I
I
L
Q
M
G
Q
K
M
G
V
K
I
S
D
E
Q
L
D
Q
A
I
A
N
I
A
K
-
Q
---------
N
N
-------
M
T
------
L
D
-
Q
----
M
R
S
R
LAYDGL
N
Y
N
-----
T
Y
-
R
---
N
Q
I
R
K
E
M
I
I
S
------
E
V
R
N
N
E
V
R
----
R
---
R
I
T
I
L
P
Q
E
V
E
S
L
A
Q
Q
V
G
N
Q
N
D
A
S
T
E
L
N
L
S
H
I
L
I
------------
P
LPENPT
S
D
Q
V
N
E
A
E
S
---------------------
Q
A
R
A
I
V
D
Q
A
------------------------------------------------------------------------------------------------------------
R
------
N
---------
D
F
G
K
L
A
I
A
H
S
A
D
Q
-
Q
--
A
L
N
G
G
Q
M
G
-
W
GR
I
Q
E
------
L
---
P
G
I
F
A
Q
A
L
S
T
A
K
K
G
D
I
V
------
G
P
I
R
S
G
-
V
G
F
H
I
L
K
V
N
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
72.48
25%
-39
- C3 -
5EZ1
1
?
A:
[24-240]
-------------------------------------------------
T
------------
K
S
D
F
------------------------------
D
M
I
K
------------------
E
K
E
K
E
A
L
I
D
Q
A
-
I
---------
R
T
-------
A
L
------
V
E
-
N
----
E
A
K
-------
T
E
K
LDST
P
E
F
-
K
A
M
M
E
A
V
K
K
Q
A
L
V
E
F
W
A
K
K
Q
A
E
----
E
V
----
K
---
K
V
Q
I
P
E
K
E
M
Q
D
F
Y
N
A
N
K
D
Q
L
F
V
K
Q
E
A
H
A
R
H
I
L
V
------------
K
------------
T
E
D
---------------------
E
A
K
R
I
I
S
E
I
D
K
QPKA------------------------------------------------------------------------------------------------------
K
------
K
------
E
-
A
K
F
I
E
L
A
N
R
D
T
I
D
P
N
S
K
N
A
Q
N
G
G
D
L
G
-
K
--
F
Q
K
----
N
Q
M
---
A
P
D
F
S
K
A
A
F
A
L
T
P
G
D
Y
T
-----
K
T
P
V
K
T
E
-
F
G
Y
H
I
I
Y
L
I
S
-
K
D
S
P
V
-
T
Y
T
Y
E
Q
A
K
P
T
I
K
------------------------------------------------------------------------------------------------------------------------------------------
48
Fugue
69.47
15%
-34
- C3 -
1M5Y
-
SURA_ECOLI
A:
[25-427]
-
V
D
K
V
A
A
V
V
--
N
N
G
V
V
L
E
S
D
V
D
G
L
M
Q
S
V
K
L
N
A
A
Q
A
R
--
Q
Q
L
P
D
---------------------------
D
A
----------------
T
L
R
H
Q
I
M
E
R
L
I
M
D
Q
I
I
L
Q
M
G
Q
K
M
G
V
K
I
S
D
E
Q
L
D
Q
A
I
A
N
I
A
K
-
Q
---------
N
N
MT
L
D
Q
M
R
S
R
------
L
A
-
Y
----
D
G
L
-------
N
Y
N
-----
T
Y
-
R
---
N
Q
I
R
K
E
M
I
I
S
------
E
V
----
R
N
----
N
---
E
V
R
R
R
I
T
I
L
P
---
Q
E
V
E
S
L
A
Q
Q
V
T
E
L
N
L
S
H
I
L
I
PLPENPT
S
D
Q
V
N
E
------------
A
E
S
---------------------
Q
A
R
A
I
V
D
Q
A
------------------------------------------------------------------------------------------------------------
R
------
N
------
G
-
A
D
F
G
K
L
A
I
A
H
S
A
D
Q
-
Q
--
A
L
N
G
G
Q
M
G
-
W
--
G
R
I
-
Q
E
---
L
---
P
G
I
F
A
Q
A
L
S
T
A
K
K
G
D
-
I
-----
V
G
P
I
R
S
G
-
V
G
F
H
I
L
K
V
N
D
-
L
R
G
E
S
-
K
N
I
S
V
T
E
V
H
A
R
H
I
L
L
K
P
S
P
I
M
--
T
D
E
----
Q
--
A
R
V
K
L
E
Q
I
A
A
D
I
K
S
G
K
T
T
F
A
A
A
A
K
E
FSQDPGSANQGGDLGWATPDIFD
P
A
F
R
D
A
L
T
R
LNKG
Q
M
S
A
PVHSSF
G
W
H
L
I
E
LL
D
T
R
N
VD
R
A
Y
R
M
L
M
N
R
K
F
S
E
E
A
A
S
W
M
Q
E
Q
R
A
S
AY
V
K
I
L
S
45
Fugue
63.40
17%
-20
- C3 -
3NRK
-
?
A:
[50-361]
-
L
N
R
V
I
A
T
V
G
-----------
T
V
S
I
S
E
L
D
L
D
D
A
T
E
K
--
Y
N
R
L
Q
K
H
L
K
H
-------------------
E
D
Y
R
K
----------------
S
F
R
T
R
I
I
D
F
L
I
D
R
A
I
V
D
V
V
A
E
E
E
S
I
Q
V
N
E
Q
R
V
D
S
E
I
E
K
R
M
E
-
V
M
GITN
R
K
Q
F
E
K
-------
T
M
------
E
T
-
S
----
S
G
M
-------
P
F
E
-----
L
W
-
V
---
T
E
L
P
Y
Q
I
K
K
G
------
Q
L
----
L
Q
----
L
K
I
A
V
P
P
P
N
E
Q
E
I
R
S
W
Y
N
Q
N
K
D
K
V
G
F
E
I
R
Y
R
I
I
S
I
A
P
------------
E
NDS
I
Q
E
E
N
R
L
--
Y
K
E
---------------------
V
S
E
I
R
K
S
I
L
------------------------------------------------------------------------------------------------------------
A
------
D
------
P
-
S
S
F
A
L
I
A
G
S
P
R
N
D
P
A
L
--
R
A
R
R
G
M
V
E
-
W
--
I
S
S
-
F
D
L
Y
K
Y
---
S
K
I
T
A
T
I
A
A
P
L
P
N
G
G
V
S
------
E
V
F
R
D
E
-
R
K
R
Y
C
I
L
K
I
E
-
G
K
R
P
T
---
P
M
E
N
L
R
G
G
I
Q
N
I
L
Y
R
D
K
E
E
--
D
T
F
----
H
R
W
L
K
E
S
R
A
E
I
P
I
Q
I
F
D
E
A
Y
R
K
E
N
K
I
P
L
K
EETFHL-------------------------------------------------------------------------------------
42
HHSearch
59.83
31%
-45
- C3 -
3UI4
6
PIN4_HUMAN
A:
[5-100]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
N
A
V
K
V
R
H
I
L
C
------------
E
------------
K
H
G
---------------------
K
I
M
E
A
M
E
K
L
------------------------------------------------------------------------------------------------------------
K
------
S
------
G
-
M
R
F
N
E
V
A
A
Q
Y
S
E
D
-
K
---
A
R
Q
G
G
D
L
G
-
W
--
M
T
R
-
G
---
S
M
---
V
G
P
F
Q
E
A
A
F
A
L
P
V
S
G
M
D
K
P
V
F
T
D
P
P
V
K
T
K
-
F
G
Y
H
I
I
M
V
E
G
-
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
59.03
24%
-43
- C3 -
3I6C
2
PIN1_HUMAN
A:
[11-123]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
P
A
R
V
R
C
S
H
L
L
V
------------
K
------------
H
S
Q
SRRPSSWRQEQITRT
Q
E
E
A
L
E
L
I
N
G
Y
I
Q
K
I
------------------------------------------------------------------------------------------------------------
K
------
S
------
G
E
E
D
F
E
S
L
A
S
Q
F
S
D
C
-
S
S
--
A
K
A
R
G
D
L
G
-
A
--
F
S
R
-
G
---
Q
M
---
Q
K
P
F
E
D
A
S
F
A
L
R
T
G
E
M
S
------
G
P
V
F
T
D
-
S
G
I
H
I
I
L
R
T
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
58.64
30%
-43
* C3 *
4G2P
3
?
A:
[6-109]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
E
V
H
A
R
H
I
L
L
------------
K
------------
P
S
P
IMN
D
Q
Q
A
R
L
------------
K
L
E
E
I
A
A
D
I
------------------------------------------------------------------------------------------------------------
K
------
S
------
G
K
T
T
F
A
A
A
A
K
E
Y
S
Q
D
P
G
S
--
A
N
Q
G
G
D
L
G
-
W
--
A
T
P
-
D
---
I
F
---
D
P
A
F
R
D
A
L
T
K
L
H
K
G
Q
I
S
------
A
P
V
H
S
S
-
F
G
W
H
L
I
E
L
L
D
-
T
R
K
---------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
58.62
31%
-43
- C3 -
4G2P
3
?
A:
[12-104]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
H
I
L
L
------------
K
P
S
PIM-------
N
D
Q
---------------------
Q
A
R
L
K
L
E
E
I
A
A
D
I
K
-------------------------------------------------------------------------------------------------------
S
------
G
------
K
-
T
T
F
A
A
A
A
K
E
Y
S
Q
D
P
G
S
--
A
N
Q
G
G
D
L
G
-
W
--
A
T
P
----
D
I
F
---
D
P
A
F
R
D
A
L
T
K
L
H
K
G
Q
I
S
------
A
P
V
H
S
S
-
F
G
W
H
L
I
E
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
58.56
27%
43
- C3 -
4WO7
-
PRSA_BACSU
A:
[4-254]
---------------------------------
G
D
K
--
E
V
I
A
K
T
D
A
G
D
V
T
------------
K
G
E
L
Y
T
N
M
K
K
----------------
T
A
G
A
S
V
L
T
Q
L
V
Q
E
K
V
L
-----
D
K
K
Y
K
V
S
D
K
E
I
D
N
K
L
K
E
Y
K
T
-
Q
---------
L
G
-------
D
Q
Y
T
A
L
--
E
K
-
Q
----
Y
G
---------
K
D
-----
Y
L
-
K
---
E
Q
V
K
Y
E
L
L
T
Q
------
K
A
----
A
K
----
D
---
N
I
K
V
T
D
A
D
I
K
E
Y
W
E
G
L
K
G
------
K
I
R
A
S
H
I
L
V
------------
A
------------
D
K
K
---------------------
T
A
E
E
V
E
K
K
L
------------------------------------------------------------------------------------------------------------
K
------
K
------
G
-
E
K
F
E
D
L
A
K
E
Y
S
T
D
-
S
S
--
A
S
K
G
G
D
L
G
-
W
--
F
A
K
E
G
---
Q
M
---
D
E
T
F
S
K
A
A
F
K
L
K
T
G
E
V
S
------
D
P
V
K
T
Q
-
Y
G
Y
H
I
I
K
K
T
E
-
E
R
G
-----
K
Y
D
D
M
K
K
E
L
K
S
E
V
L
E
Q
K
L
N
D
N
A
A
V
----
Q
E
A
V
Q
K
V
M
K
K
A
D
I
E
V
K
D
K
D
L
K
D
--------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
58.35
42%
-40
- C3 -
1ZK6
-
PRSA_BACSU
A:
[119-205]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
A
S
H
I
L
V
------------
A
------------
D
K
K
---------------------
T
A
E
E
V
E
K
K
L
------------------------------------------------------------------------------------------------------------
K
------
K
------
G
-
E
K
F
E
D
L
A
K
E
Y
S
T
D
S
S
A
--
S
K
-
G
G
D
L
G
W
F
--
A
K
E
-
G
---
Q
M
---
D
E
T
F
S
K
A
A
F
K
L
K
T
G
E
V
S
------
D
P
V
K
T
Q
-
Y
G
Y
H
I
I
K
K
T
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
58.24
21%
-45
- C3 -
4TNS
1
A:
[39-151]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
P
A
R
V
R
C
S
H
L
L
V
------------
K
------------
H
S
Q
SRRPSSWRQEQITRT
Q
E
E
A
L
E
L
I
N
G
Y
I
Q
K
I
------------------------------------------------------------------------------------------------------------
K
------
S
------
G
E
E
D
F
E
S
L
A
S
Q
F
S
D
C
-
S
S
--
A
K
A
R
G
D
L
G
-
A
--
F
S
R
-
G
---
Q
M
---
Q
K
P
F
E
D
A
S
F
A
L
R
T
G
E
M
S
------
G
P
V
F
T
D
-
S
G
I
H
I
I
L
R
T
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
56.97
28%
54
- C3 -
4WO7
-
PRSA_BACSU
A:
[3-245]
----------------------------------
S
G
DK
E
V
I
A
K
T
D
A
G
D
V
T
------------
K
G
E
L
Y
T
N
M
K
K
----------------
T
A
G
A
S
V
L
T
Q
L
V
Q
E
K
V
L
D
K
-----
K
Y
K
V
S
D
K
E
I
D
N
K
L
K
E
Y
K
T
Q
L
---------
G
D
-------
Q
Y
------
T
A
-
L
----
E
K
Q
-------
Y
G
K
-----
D
Y
L
K
---
E
Q
V
K
Y
E
L
L
T
Q
------
K
A
----
A
K
----
D
---
N
I
K
V
T
D
A
D
I
K
E
Y
W
E
------
G
L
K
G
K
I
R
A
S
H
I
L
V
------------
A
------------
D
K
K
---------------------
T
A
E
E
V
E
K
K
L
------------------------------------------------------------------------------------------------------------
K
------
K
------
G
-
E
K
F
E
D
L
A
K
E
Y
S
T
D
S
S
A
--
S
K
-
G
G
D
L
G
W
F
--
A
K
E
-
G
Q
-
M
D
-----
E
T
F
S
K
A
A
F
K
L
K
T
G
E
V
S
------
D
P
V
K
T
Q
-
Y
G
Y
H
I
I
K
K
T
E
-----
E
-
R
G
K
Y
D
D
M
K
K
E
L
K
S
E
V
L
E
Q
K
L
N
--
D
N
A
A
V
Q
E
A
--
V
Q
K
V
M
K
K
A
D
I
-----------------------------------------------------------------------------------------------------------