@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu01570: (2016-06-03 )
MNHFYVWHIKRVKQLIIILIAAFAAASFFYIQRAVPLPVFSTDTGPKAIYKGETDSKDISLTFDISWGDERAEPILNTLKANGIKNATFFLSASWAERHPDTVARIVKDGHQIGSMGYAYKNYANLESSEIKKDMNRAQTAFEKLGVKDIQLLRPPTGQFNKNVLKVAKQYNYTVVHYSVNSQDWTNPGVEKIIDNVTKQVSGGDIILLHASDSAKQTEEALPDIIHQLKEKGLKNVTVGDLIANSDAKSAEVK
Atome Classification :
(20 SA)
-------------------------------------------------------------------------------------------------------------------------------------.........10........20........30........40........50.......---.60........------------------------70........80.....-...-90......-----.-.100..----.....110.......120.........130.......140..-.-....-150....--...160.......170...----------------------...-.180...---...-------------.190-----.....----..----..---200-----....--....210....-....220...-.....230-.......240.......250..----
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------------------------------------MN
H
F
Y
V
W
H
I
K
R
V
K
Q
L
I
I
I
L
I
A
A
F
A
A
A
S
F
F
Y
IQRAVPL
P
V
FSTDTGP
K
A
I
YKGETDSK
D
---
I
S
L
T
F
D
ISWGD------------------------
E
R
A
E
P
I
L
N
T
L
K
ANGIK
N
-
A
T
F
-
F
L
S
A
S
W
AE-----R-
H
P
D
T
V
A
----
R
I
V
KDGHQIGSMGYAY--KNYANL
E
S
S
E
I
K
K
D
M
N
R
A
Q
T
A
F
E
K-L-GVK
D
-
I
Q
L
LRPP--TGQF
N
K
N
V
L
K
V
A
K
QY
N
Y
T
V
----------------------
V
H
Y
-
S
VNSQDW---TNP-------------
G
V
-------
E
K
I
I
D
----
N
V
----
T
K
---QV------SGG
D
--
I
I
L
L
H-ASDSA-
K
Q
T
E
E
-
A
L
P
D
-
I
I
H
Q
L
K
EK-GLKNV
T
V
G
D
L
IANSDAKSAEVK----
24
HHSearch
97.26
60%
-84
- C4 -
4M1B
-
?
A:
[47-246]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
I
Y
K
G
D
T
S
K
K
Q
---
V
A
F
T
F
D
I
S
W
G
D
------------------------
K
K
A
I
P
I
L
D
T
L
K
E
R
D
I
-
K
N
A
T
F
-
F
L
S
A
A
W
A
E
-----
R
-
H
P
D
V
V
E
----
R
I
I
K
D
G
H
E
I
G
S
M
G
Y
N
Y
--
T
S
Y
T
S
L
E
T
N
E
I
R
R
D
L
L
R
A
Q
D
V
F
T
K
-
L
-
G
V
K
Q
-
I
K
L
L
R
P
P
--
S
G
D
F
N
K
A
T
L
K
I
A
E
S
L
G
Y
T
V
----------------------
V
H
W
-
S
N
N
S
N
D
W
---
K
N
P
-------------
G
V
-------
N
K
I
V
S
----
T
V
----
S
N
---
N
L
------
K
G
G
D
--
I
V
L
L
H
-
A
S
D
S
A
-
L
Q
T
N
K
-
A
L
P
L
-
L
L
Q
K
L
K
S
D
-
G
Y
E
Q
I
S
V
S
Q
L
I
S
N
T
------------
21
PsiBlast_CBE
96.54
53%
-88
- C4 -
4M1B
1
?
B:
[47-246]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
I
Y
K
G
D
T
S
K
K
Q
---
V
A
F
T
F
D
I
S
W
G
D
------------------------
K
K
A
I
P
I
L
D
T
L
K
E
R
D
I
K
N
-
A
T
F
-
F
L
S
A
A
W
A
E
-----
R
-
H
P
D
V
V
E
----
R
I
I
K
D
G
H
E
I
G
S
M
G
Y
N
Y
--
T
S
Y
T
S
L
E
T
N
E
I
R
R
D
L
L
R
A
Q
D
V
F
T
K
-
L
-
G
V
K
Q
-
I
K
L
L
R
P
P
--
S
G
D
F
N
K
A
T
L
K
I
A
E
S
L
G
Y
T
V
----------------------
V
H
W
-
S
N
N
S
N
D
W
---
K
N
P
-------------
G
V
-------
N
K
I
V
S
----
T
V
----
S
N
---
N
L
------
K
G
G
D
--
I
V
L
L
H
-
A
S
D
S
A
-
L
Q
T
N
K
-
A
L
P
L
-
L
L
Q
K
L
K
S
D
-
G
Y
E
Q
I
S
V
S
Q
L
I
S
N
T
------------
1
PsiBlast_PDB
94.82
53%
-81
- C4 -
4M1B
-
?
A:
[47-246]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
I
Y
K
G
D
T
S
K
K
Q
---
V
A
F
T
F
D
I
S
W
G
D
------------------------
K
K
A
I
P
I
L
D
T
L
K
E
R
D
I
K
N
-
A
T
F
-
F
L
S
A
A
W
A
E
-----
R
-
H
P
D
V
V
E
----
R
I
I
K
D
G
H
E
I
G
S
M
G
Y
N
Y
--
T
S
Y
T
S
L
E
T
N
E
I
R
R
D
L
L
R
A
Q
D
V
F
T
K
-
L
-
G
V
K
Q
-
I
K
L
L
R
P
P
--
S
G
D
F
N
K
A
T
L
K
I
A
E
S
L
G
Y
T
V
----------------------
V
H
W
-
S
N
N
S
N
D
W
---
K
N
P
-------------
G
V
-------
N
K
I
V
S
----
T
V
----
S
N
---
N
L
------
K
G
G
D
--
I
V
L
L
H
-
A
S
D
S
A
-
L
Q
T
N
K
-
A
L
P
L
-
L
L
Q
K
L
K
S
D
-
G
Y
E
Q
I
S
V
S
Q
L
I
S
N
T
------------
2
PsiBlast_PDB
79.13
29%
-89
- C4 -
2J13
7
?
A:
[46-245]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
F
Y
L
G
D
T
K
K
K
D
---
I
Y
L
T
F
D
N
G
Y
E
N
------------------------
G
Y
T
G
K
I
L
D
V
L
K
E
K
K
V
P
--
A
T
F
-
F
V
T
G
H
Y
I
K
-----
T
-
Q
K
D
L
L
L
----
R
M
K
D
E
G
H
I
I
G
N
H
S
W
S
H
--
P
D
F
T
A
V
N
D
E
K
L
R
E
E
L
T
S
V
T
E
E
I
K
K
-
V
T
G
Q
K
E
-
V
K
Y
V
R
P
P
--
R
G
V
F
S
E
R
T
L
A
L
T
K
E
M
G
Y
Y
N
----------------------
V
F
W
-
S
L
A
F
L
D
W
-------------------------------------------------
I
------
H
P
G
S
--
I
L
L
L
H
-
A
--
I
S
-
K
D
N
A
E
-
A
L
A
K
-
I
I
D
D
L
R
E
K
-
G
Y
H
F
K
S
L
D
D
L
V
K
S
N
------------
7
PsiBlast_PDB
79.08
28%
-79
- C4 -
2C1G
4
PGDA_STRR6
A:
[224-425]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
Y
Q
S
Y
F
D
K
K
H
QK
V
V
A
L
T
F
D
D
G
P
N
P
------------------------
A
T
T
P
Q
V
L
E
T
L
A
K
Y
D
I
K
--
A
T
F
-
F
V
L
G
K
N
V
S
-----
G
-
N
E
D
L
V
K
----
R
I
K
S
E
G
H
V
V
G
N
H
S
W
S
H
--
P
I
L
S
Q
L
S
L
D
E
A
K
K
Q
I
T
D
T
E
D
V
L
T
K
-
V
-
L
G
S
S
-
S
K
L
M
R
P
P
--
Y
G
A
I
T
D
D
---
I
R
N
S
L
D
L
S
F
----------------------
I
M
W
-
D
V
D
S
L
D
W
---
K
S
K
-------------
N
E
-------
A
S
I
L
T
----
E
I
----
Q
H
---
Q
V
------
A
N
G
S
--
I
V
L
M
H
---
D
I
H
-
S
P
T
V
N
-
A
L
P
R
-
V
I
E
Y
L
K
N
Q
-
G
Y
T
F
V
T
I
P
E
M
L
-
N
T
R
L
K
A
H
E
L
-----
8
PsiBlast_PDB
78.55
27%
-75
- C4 -
2C1I
3
PGDA_STRR6
A:
[224-425]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
Y
Q
S
Y
F
D
K
K
H
QK
V
V
A
L
T
F
N
D
G
P
N
P
------------------------
A
T
T
P
Q
V
L
E
T
L
A
K
Y
D
I
K
--
A
T
F
-
F
V
L
G
K
N
V
S
-----
G
-
N
E
D
L
V
K
----
R
I
K
S
E
G
H
V
V
G
N
H
S
W
S
H
--
P
I
L
S
Q
L
S
L
D
E
A
K
K
Q
I
T
D
T
E
D
V
L
T
K
-
V
-
L
G
S
S
-
S
K
L
M
R
P
P
--
Y
G
A
I
T
D
D
---
I
R
N
S
L
D
L
S
F
----------------------
I
M
W
-
D
V
D
S
L
D
W
---
K
S
K
-------------
N
E
-------
A
S
I
L
T
----
E
I
----
Q
H
---
Q
V
------
A
N
G
S
--
I
V
L
M
H
---
D
I
H
-
S
P
T
V
N
-
A
L
P
R
-
V
I
E
Y
L
K
N
Q
-
G
Y
T
F
V
T
I
P
E
M
L
-
N
T
R
L
K
A
H
E
L
-----
46
Fugue
78.42
24%
-73
- C4 -
2C1I
4
PGDA_STRR6
A:
[14-431]
F
E
Q
K
I
E
S
L
K
K
E
K
D
D
Q
LSEG
N
Q
K
E
H
F
R
Q
GQ
A
E
V
I
A
Y
Y
P
L
QGEKVI
S
S
V
R
E
L
I
N
Q
D
V
K
DKLESKD
N
L
V
F
Y
Y
T
E
Q
E
E
SGLKG
V
V
N
R
N
V
T
K
Q
I
Y
DI
E
E
T
E
K
T
SL
G
K
V
H
L
T
ED
G
Q
P
F
T
L
D
Q
L
F
SD
A
S
K
A
K
E
Q
L
I
K
E
L
T
S
F
D
L
S
A
W
N
F
D
Y
K
D
S
Q
I
I
L
Y
E
I
A
L
P
V
S
A
F
F
D
V
I
Q
S
S
Y
L
L
--
E
K
D
A
A
L
Y
Q
S
Y
F
D
K
K
H
Q
K
V
---
V
A
L
T
F
N
D
G
P
N
P
------------------------
A
T
T
P
Q
V
L
E
T
L
A
K
Y
D
I
K
--
A
T
F
-
F
V
L
G
K
N
V
S
-----
G
-
N
E
D
L
V
K
----
R
I
K
S
E
G
H
V
V
G
N
H
S
W
S
H
--
P
I
L
S
Q
L
S
L
D
E
A
K
K
Q
I
T
D
T
E
D
V
L
T
K
-
V
-
L
G
S
S
-
S
K
L
M
R
P
P
--
Y
G
A
I
T
D
D
I
R
N
---
S
L
D
L
S
F
----------------------
I
M
W
-
D
V
D
S
L
D
W
---
K
S
K
-------------
N
E
-------
A
S
I
L
T
----
E
I
----
Q
H
---
Q
V
------
A
N
G
S
--
I
V
L
M
H
---
D
I
H
-
S
P
T
V
N
-
A
L
P
R
-
V
I
E
Y
L
K
N
Q
-
G
Y
T
F
V
T
I
P
E
M
L
N
T
R
L
K
A
H
E
L
Y
Y
SRDE
27
HHSearch
77.47
29%
-64
- C4 -
2CC0
2
?
A:
[3-191]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
N
G
Y
---
V
G
L
T
F
D
D
G
P
S
G
-------------------------
S
T
Q
S
L
L
N
A
L
R
Q
N
G
L
-
R
-
A
T
M
-
F
N
Q
G
Q
Y
A
A
-----
Q
-
N
P
S
L
V
R
----
A
Q
V
D
A
G
M
W
V
A
N
H
S
Y
T
H
--
P
H
M
T
Q
L
G
Q
A
Q
M
D
S
E
I
S
R
T
Q
Q
A
I
A
G
-
A
-
G
G
G
T
-
P
K
L
F
R
P
P
--
Y
G
E
T
N
A
T
L
R
S
V
E
A
K
Y
G
L
T
E
----------------------
V
I
W
-
D
V
D
S
Q
D
W
---
N
N
A
-------------
S
T
-------
D
A
I
V
Q
----
A
V
-----
S
---
R
L
------
G
N
G
Q
--
V
I
L
M
H
-
D
W
P
A
---
N
T
L
A
-
A
I
P
R
-
I
A
Q
T
L
A
G
K
-
G
L
C
S
G
M
I
S
P
Q
T
G
R
A
V
A
----------
32
HHSearch
77.40
27%
-76
- C4 -
2C1I
3
PGDA_STRR6
A:
[231-422]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
K
H
Q
K
V
---
V
A
L
T
F
N
D
G
P
N
P
------------------------
A
T
T
P
Q
V
L
E
T
L
A
K
Y
D
I
-
K
-
A
T
F
-
F
V
L
G
K
N
V
S
-----
G
-
N
E
D
L
V
K
----
R
I
K
S
E
G
H
V
V
G
N
H
S
W
S
H
--
P
I
L
S
Q
L
S
L
D
E
A
K
K
Q
I
T
D
T
E
D
V
L
T
K
-
V
-
L
G
S
S
-
S
K
L
M
R
P
P
--
Y
G
A
I
T
D
D
I
R
N
---
S
L
D
L
S
F
----------------------
I
M
W
-
D
V
D
S
L
D
W
---
K
S
K
-------------
N
E
-------
A
S
I
L
T
----
E
I
----
Q
H
---
Q
V
------
A
N
G
S
--
I
V
L
M
H
-
D
I
H
S
---
P
T
V
N
-
A
L
P
R
-
V
I
E
Y
L
K
N
Q
-
G
Y
T
F
V
T
I
P
E
M
L
N
T
R
L
K
A
---------
25
HHSearch
77.22
28%
-80
- C4 -
2J13
7
?
A:
[44-245]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
G
G
F
Y
L
G
D
T
K
K
K
D
---
I
Y
L
T
F
D
N
G
Y
E
N
------------------------
G
Y
T
G
K
I
L
D
V
L
K
E
K
K
V
-
P
-
A
T
F
-
F
V
T
G
H
Y
I
K
-----
T
-
Q
K
D
L
L
L
----
R
M
K
D
E
G
H
I
I
G
N
H
S
W
S
H
--
P
D
F
T
A
V
N
D
E
K
L
R
E
E
L
T
S
V
T
E
E
I
K
K
-
V
-
T
G
Q
K
E
V
K
Y
V
R
P
P
--
R
G
V
F
S
E
R
T
L
A
L
T
K
E
M
G
Y
Y
N
----------------------
V
F
W
-
S
L
A
F
L
D
W
-------------------------------------------------
I
------
H
P
G
S
--
I
L
L
L
H
-
A
I
S
K
---
D
N
A
E
-
A
L
A
K
-
I
I
D
D
L
R
E
K
-
G
Y
H
F
K
S
L
D
D
L
V
K
S
N
------------
5
PsiBlast_PDB
74.74
30%
-73
- C4 -
2CC0
2
?
A:
[7-177]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
L
T
F
D
D
G
-
P
S
------------------------
G
S
T
Q
S
L
L
N
A
L
R
Q
N
G
L
R
--
A
T
M
-
F
N
Q
G
Q
Y
A
A
-----
Q
-
N
P
S
L
V
R
----
A
Q
V
D
A
G
M
W
V
A
N
H
S
Y
T
H
--
P
H
M
T
Q
L
G
Q
A
Q
M
D
S
E
I
S
R
T
Q
Q
A
I
A
G
-
A
-
G
G
G
T
-
P
K
L
F
R
P
P
--
Y
G
E
T
N
A
T
L
R
S
V
E
A
K
Y
G
L
T
E
----------------------
V
I
W
-
D
V
D
S
Q
D
W
---
N
N
A
-------------
S
T
-------
D
A
I
V
Q
----
A
V
----
S
R
----
L
------
G
N
G
Q
--
V
I
L
M
H
---
D
W
P
-
A
N
T
L
A
-
A
I
P
R
-
I
A
Q
T
L
A
G
K
-
G
L
------------------------
34
HHSearch
74.44
25%
-66
- C4 -
2C71
1
?
A:
[5-195]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
---
V
A
L
T
F
D
D
G
P
D
N
------------------------
V
L
T
A
R
V
L
D
K
L
D
K
Y
N
V
-
K
-
A
T
F
-
M
V
V
G
Q
R
V
N
-----
D
S
T
A
A
I
I
R
----
R
M
V
N
S
G
H
E
I
G
N
H
S
W
S
Y
--
S
G
M
A
N
M
S
P
D
Q
I
R
K
S
I
A
D
T
N
A
V
I
Q
K
-
Y
-
A
G
T
T
-
P
K
F
F
R
P
P
--
N
L
E
T
S
P
T
L
F
N
N
V
---
D
L
V
-----------------------
F
V
G
-
G
L
T
A
N
D
W
---
I
P
S
-------------
T
T
A
------
E
Q
R
A
A
----
A
V
----
I
N
---
G
V
------
R
D
G
T
--
I
I
L
L
H
-
D
V
Q
P
E
P
H
P
T
P
E
-
A
L
D
I
-
I
I
P
T
L
K
S
R
-
G
Y
E
F
V
T
L
T
E
L
F
T
L
K
G
V
P
---------
3
PsiBlast_PDB
74.39
29%
-11
- C- -
1W17
-
PDAA_BACSU
A:
[57-259]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
F
Y
L
G
N
T
K
E
K
T
---
I
Y
L
T
F
D
N
G
Y
E
N
------------------------
G
Y
T
P
K
V
L
D
V
L
K
K
H
R
V
-
T
-
G
T
F
-
F
V
T
G
H
F
V
K
-----
D
-
Q
P
Q
L
I
K
----
R
M
S
D
E
G
H
I
I
G
N
H
S
F
H
H
--
P
D
L
T
T
K
T
A
D
Q
I
Q
D
E
L
D
S
V
N
E
E
V
Y
K
-
I
T
G
K
Q
D
-
N
L
Y
L
R
P
P
--
R
G
V
F
S
E
Y
V
L
K
E
T
K
R
L
G
Y
Q
T
----------------------
V
F
W
-
S
V
A
F
V
D
W
KIN
N
Q
K
-------------
G
K
-------
K
Y
A
Y
D
----
H
M
----
I
K
---
Q
A
------
H
P
G
A
--
I
Y
L
L
H
-
T
--
V
S
-
R
D
N
A
E
-
A
L
D
D
-
A
I
T
D
L
K
K
Q
-
G
Y
T
F
K
S
I
D
D
L
M
F
E
K
E
M
R
---------
29
HHSearch
74.34
26%
-60
- C4 -
2Y8U
6
?
A:
[25-228]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
I
T
Q
C
T
T
P
N
T
---
I
A
L
T
F
D
D
G
P
S
E
-------------------------
Y
T
P
Q
L
L
D
L
L
S
R
Y
S
A
-
R
-
A
T
F
-
F
V
L
G
D
A
A
A
-----
Q
-
N
P
G
L
L
Q
----
R
M
R
D
E
G
H
Q
V
G
A
H
T
Y
D
H
--
V
S
L
P
S
L
G
Y
D
G
I
A
S
Q
M
T
R
L
E
E
V
I
R
P
-
A
-
L
G
V
A
-
P
A
Y
M
R
P
P
--
Y
L
E
T
N
E
L
V
L
Q
V
M
R
D
L
D
Y
R
V
----------------------
I
S
A
-
S
V
D
T
K
D
Y
---
E
N
Q
-------------
D
A
-------
D
A
I
I
N
----
T
S
F
Q
L
F
L
D
---
Q
L
D
-----
A
G
G
N
--
I
V
L
A
H
-
D
I
H
Y
---
W
T
V
A
S
L
A
E
R
-
M
L
Q
E
V
N
A
R
-
G
L
I
A
T
T
V
G
D
C
L
G
D
G
E
I
A
W
--------
37
HHSearch
73.88
19%
-68
* C4 *
3RXZ
2
?
A:
[16-280]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
V
S
W
P
D
G
K
T
C
A
---
V
A
F
T
F
D
V
D
A
E
S
P
L
L
T
T
DPAFADR
M
G
T
M
S
H
Q
A
Y
G
P
L
V
G
V
P
R
L
L
G
I
L
D
E
F
N
V
-
P
-
G
T
F
-
F
V
P
G
Y
T
A
H
-----
R
-
H
P
E
P
I
R
----
S
I
A
R
A
G
H
E
I
A
H
H
G
Y
L
H
--
E
S
L
V
G
A
D
E
D
T
E
R
K
I
L
T
R
G
I
E
A
L
E
E
-
V
-
A
G
V
H
-
P
V
G
Y
R
A
P
--
M
W
E
M
N
W
H
T
P
K
L
L
A
E
F
G
F
L
Y
DSTLMDSD
H
P
Y
E
L
AVGD
G
S
L
V
E
L
P
V
-
S
W
A
L
D
D
W
---
Q
Q
Y
C
F
V
P
DFSGTG
L
I
E
T
P
-------
A
K
A
I
E
L
W
R
A
E
L
----
N
A
---
M
R
------
D
I
G
G
A
W
V
L
T
N
H
-
P
F
L
S
G
R
P
G
R
A
A
-
A
L
R
E
-
F
I
A
E
V
C
A
M
D
D
V
W
V
A
G
M
S
Q
I
A
E
H
V
------------
28
HHSearch
73.40
24%
-63
- C4 -
2IW0
6
?
A:
[34-245]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
I
L
Q
C
T
Q
P
G
L
---
V
A
L
T
Y
D
D
G
P
F
T
-------------------------
F
T
P
Q
L
L
D
I
L
K
Q
N
D
V
-
R
-
A
T
F
-
F
V
N
G
N
N
W
A
NIEAG
S
-
N
P
D
T
I
R
----
R
M
R
A
D
G
H
L
V
G
S
H
T
Y
A
H
--
P
D
L
N
T
L
S
S
A
D
R
I
S
Q
M
R
Q
L
E
E
A
T
R
R
-
I
-
D
G
F
A
-
P
K
Y
M
R
A
P
--
Y
L
S
C
D
A
G
C
Q
G
D
L
G
G
L
G
Y
H
I
----------------------
I
D
T
-
N
L
D
T
K
D
Y
---
E
N
N
-------------
K
P
ET
T
H
L
S
A
E
K
F
N
N
----
E
L
----
S
A
---
D
V
G-----
A
N
S
Y
--
I
V
L
S
H
-
D
V
H
E
Q
--
T
V
V
S
-
L
T
Q
K
-
L
I
D
T
L
K
S
K
-
G
Y
R
A
V
T
V
G
E
C
L
G
D
A
P
E
N
W
--------
10
PsiBlast_PDB
73.10
27%
-67
- C4 -
2C71
1
?
A:
[5-188]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
---
V
A
L
T
F
D
D
G
P
D
N
------------------------
V
L
T
A
R
V
L
D
K
L
D
K
Y
N
V
K
--
A
T
F
-
M
V
V
G
---
Q
-----
R
-
V
N
D
S
T
A
A
I
I
R
R
M
V
N
S
G
H
E
I
G
N
H
S
W
S
Y
--
S
G
M
A
N
M
S
P
D
Q
I
R
K
S
I
A
D
T
N
A
V
I
Q
K
-
Y
-
A
G
T
T
-
P
K
F
F
R
P
P
--
N
L
E
T
S
P
T
L
F
N
-----
N
V
D
L
----------------------
V
F
V
G
G
L
T
A
N
D
W
I--
P
S
T
-------------
T
A
-------
E
Q
R
A
A
----
A
V
----
I
N
---
G
V
------
R
D
G
T
--
I
I
L
L
H
D
V
Q
P
E
P
-
H
P
T
P
E
-
A
L
D
I
-
I
I
P
T
L
K
S
R
-
G
Y
E
F
V
T
L
T
E
L
----------------
11
PsiBlast_PDB
72.36
27%
-68
- C4 -
2C79
1
?
A:
[5-188]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
---
V
A
L
T
F
D
D
G
P
D
N
------------------------
V
L
T
A
R
V
L
D
K
L
D
K
Y
N
V
K
--
A
T
F
-
M
V
V
G
---
Q
-----
R
-
V
N
D
S
T
A
A
I
I
R
R
M
V
N
S
G
H
E
I
G
N
H
S
W
S
Y
--
S
G
M
A
N
M
S
P
D
Q
I
R
K
S
I
A
D
T
N
A
V
I
Q
K
-
Y
-
A
G
T
T
-
P
K
F
F
R
P
P
--
N
L
E
T
S
P
T
L
F
N
-----
N
V
D
L
----------------------
V
F
V
G
G
L
T
A
N
D
W
I--
P
S
T
-------------
T
A
-------
E
Q
R
A
A
----
A
V
----
I
N
---
G
V
------
R
D
G
T
--
I
I
L
L
H
D
V
Q
P
E
P
-
H
P
T
P
E
-
A
L
D
I
-
I
I
P
T
L
K
S
R
-
G
Y
E
F
V
T
L
T
E
L
----------------
6
PsiBlast_PDB
70.42
29%
-28
- C4 -
2Y8U
6
?
A:
[20-225]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
T
G
Q
V
I
T
Q
C
T
T
P
N
T
----
I
A
L
T
F
D
D
--
G
P
------------------------
S
E
Y
T
P
Q
L
L
D
L
L
S
R
Y
S
A
R
-
A
T
F
-
F
V
L
G
D
A
A
A
-----
Q
-
N
P
G
L
L
Q
----
R
M
R
D
E
G
H
Q
V
G
A
H
T
Y
D
H
--
V
S
L
P
S
L
G
Y
D
G
I
A
S
Q
M
T
R
L
E
E
V
I
R
P
A
L
-
G
V
A
P
--
A
Y
M
R
P
P
--
Y
L
E
T
N
E
L
V
L
Q
V
M
R
D
L
D
Y
R
V
----------------------
I
S
A
-
S
V
D
T
K
D
Y
---
E
N
Q
-------------
D
A
-------
D
A
I
I
-----
N
T
----
S
F
---
Q
L
F
L
D
Q
L
D
A
G
G
N
--
I
V
L
A
H
---
D
I
H
-
Y
W
T
V
A
-
S
L
A
E
R
M
L
Q
E
V
N
A
R
-
G
L
I
A
T
T
V
G
D
C
L
G
D
G
E
-----------
35
HHSearch
67.57
22%
-67
- C4 -
2VYO
10
YB51_ENCCU
A:
[21-220]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
C
T
N
S
G
M
---
I
A
I
N
F
V
D
G
P
V
R
------------------------
G
V
T
D
R
I
L
N
T
L
D
E
L
G
V
-
K
-
A
T
F
S
F
T
V
N
Q
K
A
V
-----
G
N
V
G
Q
L
Y
R
----
R
A
V
E
E
G
H
N
V
A
L
R
V
D
P
S
MD
E
G
Y
Q
C
L
S
Q
D
A
L
E
N
N
V
D
R
E
I
D
T
I
D
G
-
L
-
S
G
T
E
-
I
R
Y
A
A
V
P
IC
N
G
Q
V
N
S
E
M
Y
N
I
L
T
E
R
G
V
L
P
----------------------
V
G
Y
-
T
F
C
P
Y
D
Y
---
D
D
P
--------------
V
-------
G
E
-
F
E
----
S
M
----
I
E
G
SD
P
K
------
H
H
S
F
--
I
I
L
M
H
-
D
G
Q
E
---
A
D
T
S
-
R
L
E
N
-
M
V
K
I
G
K
D
K
-
G
Y
R
F
V
N
M
D
E
C
L
Q
G
Y
K
-----------