@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu01750: (2016-06-03 )
MAFEDIPFLQYLGNAVDILLVWYVIYKLIMVIRGTKAVQLLKGIVVIVLVRMASQYLGLSTLQWLMDQAITWGFLAIIIIFQPELRRALEQLGRGRFFSRSGTPVEEAQQKTIEAITKAINYMAKRRIGALLTIERDTGMGDYIETGIPLNAKVSSELLINIFIPNTPLHDGAVIMKNNEIAAAACYLPLSESPFISKELGTRHRAAVGISEVTDSLTIIVSEETGGVSVAKNGDLHRELTEEALKEMLEAEFKKNTRDTSSNRWYWRGKKNG
Atome Classification :
(20 SA)
----------------------------------------------------------------------.........10........20-----------.----.......30..-------------......40--..-------------------.....----..50..--....-----..60.......--------------------------.70........80........90......-------------..100.......110.-----......120.......130....-.-.-.140.......150--------.......160...-----....170......--.--180.......190...-.-...200..-.....210.......220.......230--.........240.......250.......260----........270.---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------------MAFEDI
P
F
L
Q
Y
L
G
N
A
V
D
I
L
L
V
-----------
W
----
Y
V
I
Y
K
L
I
M
V
IR-------------G
T
K
A
V
Q
L
---
L
K
-------------------
G
I
V
V
I
----
V
L
V
R
M
A
--
S
Q
YL-----
G
L
S
T
L
Q
W
L
M
D
Q--------------------------
A
I
T
W
G
F
L
A
I
I
I
I
F
Q
P
E
L
R
R
A
L
E
Q
LGRG
R
F
-------------FSRSGT
P
V
E
E
A
Q
Q
K
T
I
-----
E
A
I
T
K
A
I
N
Y
M
A
K
RRI
G
A
L
L
T
I
ER-D-T-GMG
D
Y
I
ETGIPLNA--------KVS
S
E
L
L
I
N
I
F
IP-----NTPLHD
G
A
V
I
M
KN--N--
E
I
A
A
A
A
C
Y
LPLSESPF-
I
-
S
K
E
LGT
R
H
-
R
AAV
G
I
S
EVTD
S
L
T
I
I
V
SEETG
G
V
S
V----AKNG
D
L
H
R
E
L
T
E
E
A
L
K
E
M
L
E
A
E
F
KKNTRDTS-----SN
R
W
Y
W
RGKKNG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
99.19
64%
-126
- C2 -
4RV7
3
DACA_LISMO
B:
[19-176]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Y
G
S
R
I
E
R
E
Q
H
H
L
I
-----
E
S
I
E
K
S
T
Q
Y
M
A
K
R
R
I
G
A
L
I
S
V
A
R
-
D
-
T
-
G
M
D
D
Y
I
E
T
G
I
P
L
N
A
--------
K
I
S
S
Q
L
L
I
N
I
F
I
P
-----
N
T
P
L
H
D
G
A
V
I
I
K
G
--
N
--
E
I
A
S
A
A
S
Y
L
P
L
S
D
S
P
F
-
L
-
S
K
E
L
G
T
R
H
-
R
A
A
L
G
I
S
E
V
T
D
S
I
T
I
V
V
S
E
E
T
G
G
I
S
L
----
T
K
G
G
E
L
F
R
D
V
S
E
E
E
L
H
K
I
L
L
K
E
L
V
T
V
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
98.71
64%
-127
- C2 -
4RV7
3
DACA_LISMO
C:
[18-176]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
Y
G
S
R
I
E
R
E
Q
H
H
L
I
-----
E
S
I
E
K
S
T
Q
Y
M
A
K
R
R
I
G
A
L
I
S
V
A
R
-
D
-
T
-
G
M
D
D
Y
I
E
T
G
I
P
L
N
A
--------
K
I
S
S
Q
L
L
I
N
I
F
I
P
-----
N
T
P
L
H
D
G
A
V
I
I
K
G
--
N
--
E
I
A
S
A
A
S
Y
L
P
L
S
D
S
P
F
-
L
-
S
K
E
L
G
T
R
H
-
R
A
A
L
G
I
S
E
V
T
D
S
I
T
I
V
V
S
E
E
T
G
G
I
S
L
----
T
K
G
G
E
L
F
R
D
V
S
E
E
E
L
H
K
I
L
L
K
E
L
V
T
V
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
97.94
64%
-123
- C2 -
4RV7
4
DACA_LISMO
A:
[18-176]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
Y
G
S
R
I
E
R
E
Q
H
H
L
I
-----
E
S
I
E
K
S
T
Q
Y
M
A
K
R
R
I
G
A
L
I
S
V
A
R
-
D
-
T
-
G
M
D
D
Y
I
E
T
G
I
P
L
N
A
--------
K
I
S
S
Q
L
L
I
N
I
F
I
P
-----
N
T
P
L
H
D
G
A
V
I
I
K
G
--
N
--
E
I
A
S
A
A
S
Y
L
P
L
S
D
S
P
F
-
L
-
S
K
E
L
G
T
R
H
-
R
A
A
L
G
I
S
E
V
T
D
S
I
T
I
V
V
S
E
E
T
G
G
I
S
L
----
T
K
G
G
E
L
F
R
D
V
S
E
E
E
L
H
K
I
L
L
K
E
L
V
T
V
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
97.81
64%
-129
- C2 -
4RV7
2
DACA_LISMO
D:
[20-174]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
G
S
R
I
E
R
E
Q
H
H
L
I
-----
E
S
I
E
K
S
T
Q
Y
M
A
K
R
R
I
G
A
L
I
S
V
A
R
-
D
-
T
-
G
M
D
D
Y
I
E
T
G
I
P
L
N
A
--------
K
I
S
S
Q
L
L
I
N
I
F
I
P
-----
N
T
P
L
H
D
G
A
V
I
I
K
G
--
N
--
E
I
A
S
A
A
S
Y
L
P
L
S
D
S
P
F
-
L
-
S
K
E
L
G
T
R
H
-
R
A
A
L
G
I
S
E
V
T
D
S
I
T
I
V
V
S
E
E
T
G
G
I
S
L
----
T
K
G
G
E
L
F
R
D
V
S
E
E
E
L
H
K
I
L
L
K
E
L
V
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
95.05
60%
-123
- C2 -
4RV7
4
DACA_LISMO
A:
[18-176]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
-------------
S
Y
G
S
--
R
I
E
R
E
Q
H
H
L
I
-----
E
S
I
E
K
S
T
Q
Y
M
A
K
R
R
I
G
A
L
I
S
V
A
R
-
D
-
T
-
G
M
D
D
Y
I
E
T
G
I
P
L
N
A
--------
K
I
S
S
Q
L
L
I
N
I
F
I
P
-----
N
T
P
L
H
D
G
A
V
I
I
K
G
--
N
--
E
I
A
S
A
A
S
Y
L
P
L
S
D
S
P
F
-
L
-
S
K
E
L
G
T
R
H
-
R
A
A
L
G
I
S
E
V
T
D
S
I
T
I
V
V
S
E
E
T
G
G
I
S
L
----
T
K
G
G
E
L
F
R
D
V
S
E
E
E
L
H
K
I
L
L
K
E
L
V
T
V
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
81.84
48%
-125
- C2 -
2FB5
-
?
A:
[74-203]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
S
S
-----
S
F
I
T
T
A
I
Q
H
L
S
A
R
K
H
G
A
L
I
V
V
E
R
-
N
-
E
-
T
L
E
A
L
I
Q
T
G
T
T
L
N
A
--------
H
L
T
A
P
L
L
E
S
I
F
Y
P
-----
G
N
P
L
H
D
G
A
V
L
V
K
N
--
N
--
H
I
V
S
A
A
N
I
L
P
L
T
K
S
T
E
-
V
-
D
P
E
L
G
T
R
H
-
R
A
A
I
G
L
S
E
K
S
D
A
L
I
L
V
V
S
E
E
T
G
R
T
S
F
----
A
L
N
G
I
L
Y
T
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
80.74
51%
-139
- C2 -
2FB5
-
?
A:
[80-201]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
T
A
I
Q
H
L
S
A
R
K
H
G
A
L
I
V
V
E
R
-
N
-
E
-
T
L
E
A
L
I
Q
T
G
T
T
L
N
A
--------
H
L
T
A
P
L
L
E
S
I
F
Y
P
-----
G
N
P
L
H
D
G
A
V
L
V
K
N
--
N
--
H
I
V
S
A
A
N
I
L
P
L
T
K
S
T
E
-
V
-
D
P
E
L
G
T
R
H
-
R
A
A
I
G
L
S
E
K
S
D
A
L
I
L
V
V
S
E
E
T
G
R
T
S
F
----
A
L
N
G
I
L
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
Fugue
79.60
20%
-92
* C2 *
3C1Y
1
DISA_THEMA
A:
[27-375]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
Q
E
L
I
E
K
I
K
L
I
S
P
G
------------------------------------
T
E
L
R
K
A
L
D
D
I
I
N
A
N
F
G
A
L
I
F
L
V
D
D
P
-
K
-
K
Y
E
D
V
I
Q
G
G
F
W
L
D
T
--------
D
F
S
A
E
K
L
Y
E
L
S
----------
K
M
D
G
A
I
V
L
S
E
--
D
IT
K
I
Y
Y
A
N
V
H
L
V
P
D
P
T
I
--
P
-
T
G
E
T
G
T
R
H
-
R
T
A
E
R
L
A
K
Q
T
G
K
V
V
I
A
V
S
R
R
R
N
I
I
S
L
----
Y
Y
K
N
Y
K
Y
V
V
N
Q
V
D
F
L
I
S
K
V
T
Q
A
I
S
T
L
E
K
Y
K
D
-----
N
F
N
K
L
L
S
E
L
E
V
L
E
L
E
NRVT
L
A
D
V
V
R
T
L
A
K
G
F
E
L
L
R
I
V
E
E
I
R
P
Y
I
V
E
L
GEEG
R
L
A
R
M
Q
L
R
E
L
T
ED
V
D
D
L
L
V
L
L
I
M
D
Y
SSEEVE
E
E
T
A
Q
N
I
L
Q
D
F
I
TRREPS
P
I
S
I
S
R
V
L
GYDVQQAAQLDD
V
L
V
S
A
RG
Y
R
L
L
K
TVARIP
L
S
I
G
Y
N
V
V
R
M
FKT
L
D
Q
I
S
K
AS
V
E
D
L
K
KVEGIG
E
K
R
A
R
A
I
S
E
S
I
S
S
L
K
H
R
KT
26
HHSearch
71.40
22%
-97
- C2 -
3C1Y
1
DISA_THEMA
A:
[27-183]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
Q
E
L
I
E
K
I
K
L
I
S
P
G
------------------------------------
T
E
L
R
K
A
L
D
D
I
I
N
A
N
F
G
A
L
I
F
L
V
D
-
D
-
P
K
K
Y
E
D
V
I
Q
G
G
F
W
L
D
T
--------
D
F
S
A
E
K
L
Y
E
L
----------
S
K
M
D
G
A
I
V
L
S
E
DI
T
--
K
I
Y
Y
A
N
V
H
L
V
P
D
P
T
-
I
-
P
-
T
G
E
T
G
T
R
H
-
R
T
A
E
R
L
A
K
Q
T
G
K
V
V
I
A
V
S
R
R
R
N
I
I
S
L
----
Y
Y
K
N
Y
K
Y
V
V
N
Q
V
D
F
L
I
S
K
V
T
Q
A
I
S
T
L
E
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
66.84
26%
-111
- C2 -
3C1Z
-
DISA_THEMA
A:
[24-135]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
K
A
L
D
D
I
I
N
A
N
F
G
A
L
I
F
L
V
D
-
D
P
K
-
K
Y
E
D
V
I
Q
G
G
F
W
L
D
T
--------
D
F
S
A
E
K
L
Y
E
L
----------
S
K
M
D
G
A
I
V
L
S
E
--
D
--
I
T
K
I
Y
Y
A
N
V
H
L
V
P
D
P
T
-
I
P
T
G
E
T
G
T
R
H
-
R
T
A
E
R
L
A
K
Q
T
G
K
V
V
I
A
V
S
R
R
R
N
I
I
S
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
66.72
26%
-111
- C2 -
4YXM
2
DISA_THEMA
A:
[44-155]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
K
A
L
D
D
I
I
N
A
N
F
G
A
L
I
F
L
V
D
-
D
P
K
-
K
Y
E
D
V
I
Q
G
G
F
W
L
D
T
--------
D
F
S
A
E
K
L
Y
E
L
S
K
M
-----
N
-----
G
A
I
V
L
S
E
--
D
--
I
T
K
I
Y
Y
A
N
V
H
L
V
P
D
P
T
-
I
P
T
G
E
T
G
T
R
H
-
R
T
A
E
R
L
A
K
Q
T
G
K
V
V
I
A
V
S
R
R
R
N
I
I
S
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
66.58
26%
-109
- C2 -
4YXJ
2
DISA_THEMA
A:
[44-155]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
K
A
L
D
D
I
I
N
A
N
F
G
A
L
I
F
L
V
D
-
D
P
K
-
K
Y
E
D
V
I
Q
G
G
F
W
L
D
T
--------
D
F
S
A
E
K
L
Y
E
L
----------
S
K
M
D
G
A
I
V
L
S
E
--
D
--
I
T
K
I
Y
Y
A
N
V
H
L
V
P
D
P
T
-
I
P
T
G
E
T
G
T
R
H
-
R
T
A
E
R
L
A
K
Q
T
G
K
V
V
I
A
V
S
R
R
R
N
I
I
S
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
66.15
26%
-104
- C2 -
4YVZ
3
DISA_THEMA
A:
[44-155]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
K
A
L
D
D
I
I
N
A
N
F
G
A
L
I
F
L
V
D
-
D
P
K
-
K
Y
E
D
V
I
Q
G
G
F
W
L
D
T
--------
D
F
S
A
E
K
L
Y
E
L
----------
S
K
M
D
G
A
I
V
L
S
E
--
D
--
I
T
K
I
Y
Y
A
N
V
H
L
V
P
D
P
T
-
I
P
T
G
E
T
G
T
R
H
-
R
T
A
E
R
L
A
K
Q
T
G
K
V
V
I
A
V
S
R
R
R
N
I
I
S
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
65.95
26%
-111
- C2 -
3C1Y
1
DISA_THEMA
A:
[44-155]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
K
A
L
D
D
I
I
N
A
N
F
G
A
L
I
F
L
V
D
-
D
P
K
-
K
Y
E
D
V
I
Q
G
G
F
W
L
D
T
--------
D
F
S
A
E
K
L
Y
E
L
----------
S
K
M
D
G
A
I
V
L
S
E
--
D
--
I
T
K
I
Y
Y
A
N
V
H
L
V
P
D
P
T
-
I
P
T
G
E
T
G
T
R
H
-
R
T
A
E
R
L
A
K
Q
T
G
K
V
V
I
A
V
S
R
R
R
N
I
I
S
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
65.73
26%
-106
- C2 -
3C21
1
DISA_THEMA
A:
[44-155]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
K
A
L
D
D
I
I
N
A
N
F
G
A
L
I
F
L
V
D
-
D
P
K
-
K
Y
E
D
V
I
Q
G
G
F
W
L
D
T
--------
D
F
S
A
E
K
L
Y
E
L
----------
S
K
M
D
G
A
I
V
L
S
E
--
D
--
I
T
K
I
Y
Y
A
N
V
H
L
V
P
D
P
T
-
I
P
T
G
E
T
G
T
R
H
-
R
T
A
E
R
L
A
K
Q
T
G
K
V
V
I
A
V
S
R
R
R
N
I
I
S
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
65.46
26%
-110
- C2 -
3C23
2
DISA_THEMA
A:
[44-155]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
K
A
L
D
D
I
I
N
A
N
F
G
A
L
I
F
L
V
D
-
D
P
K
-
K
Y
E
D
V
I
Q
G
G
F
W
L
D
T
--------
D
F
S
A
E
K
L
Y
E
L
----------
S
K
M
D
G
A
I
V
L
S
E
--
D
--
I
T
K
I
Y
Y
A
N
V
H
L
V
P
D
P
T
-
I
P
T
G
E
T
G
T
R
H
-
R
T
A
E
R
L
A
K
Q
T
G
K
V
V
I
A
V
S
R
R
R
N
I
I
S
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
61.33
19%
-51
- C1 -
4N0N
9
A:
[22-422]
SAVCTVCGAAPVAKSACG
G
W
F
C
GNCVPYHAGH
C
H
T
T
S
LFANCGHDIMYRSTYCTMCEGSPKQM
V
P
K
V
P
H
P
I
L
D
H
L
L
C
H
I
D
Y
G
S
K
E
E
L
T
L
V
V
A
DGRTT
S
P
P
G
R
Y
----
K
V
G
H
K
V
V
A
V
V
A
D
VG
G
N
I
V
F
GCGPG
S
H
I
A
V
P
L
Q
D
T
L
K
-------------------
G
V
V
V
N
----
K
A
L
K
N
A
A
A
S
E
Y
V
E
G
P
PG
S
G
K
T
F
H
L
V
K
D
V
--------------------------
L
A
V
V
G
S
A
T
L
V
V
P
T
H
A
S
M
L
D
C
I
N
K
L
K
Q
A
G
A
D
P
Y
F
V
V
P
KYTV
L
D
F
P
R
P
G
S
G
N
I
T
V
R
L
P
Q
V
G
T
S
E
G
E
T
F
V
D
E
V
A
Y
F
S
P
V
D
L
A
R
I
L
T
Q
G
R
-
V
-
K
-
G
Y
G
D
L
N
Q
L
G
C
V
G
P
A
--------
S
V
P
R
N
L
W
L
R
H
F
V
S
-----
L
E
P
L
R
------
V
C
--
H
--
R
F
G
A
A
V
C
D
L
I
K
G
I
Y
P
Y
-
Y
-
E
P
A
P
H
T
T
K
-
V
V
F
V
P
N
P
D
F
E
K
G
V
V
I
T
A
Y
H
K
D
R
G
L
G
H
----
R
T
I
D
S
I
Q
G
C
T
F
P
V
V
T
L
R
L
P
T
P
Q
S
L
T
R
P
R
A
V
V
A
V
T
RA
S
Q
E
L
Y
I
Y
D
P
F
D
Q
L
S
G
L
L
KF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
47.59
11%
-85
- C2 -
3MS5
13
BODG_HUMAN
A:
[1-385]
----------------------------------------------------------------------
S
M
A
C
T
I
Q
K
A
E
A
L
D
G
A
H
L
M
Q
I
L
-----------
W
YDE
E
E
S
L
Y
P
A
V
W
L
R
D
-------------
N
C
P
C
S
D
C
---
Y
L
DSAKARKLLVEALDVNIGI
K
G
L
I
F
D
RK
K
V
Y
I
T
W
P
--
D
E
H
Y
-----
S
E
F
Q
A
D
W
L
K
K
R
CFS
K
Q
A
R
A
K
L
Q
R
E
L
FFP
E
C
Q
Y
W
G
SEL
Q
L
P
T
L
D
F
E
D
V
L
R
Y
D
E
H
A
Y
K
W
L
S
T
L
K
K
V
G
I
-------------
V
R
L
T
G
A
S
---
D
K
P
G
E
V
-----
S
K
L
G
K
R
M
G
F
L
Y
L
T
F
Y
G
H
T
W
Q
V
Q
D
-
K
-
I
-
D
A
N
N
V
A
Y
T
T
G
K
L
S
F
HTDYPALH
H
P
P
G
V
Q
L
L
H
C
I
K
Q
TVTGG
D
S
E
I
V
D
G
F
N
V
C
Q
K
--
L
--
K
K
N
N
P
Q
A
F
Q
I
L
S
S
T
F
V
-
D
-
F
T
D
I
G
V
D
Y
-
C
----
D
F
S
V
Q
S
K
H
K
I
I
E
L
D
D
K
G
Q
V
V
R
I
N
F
N
N
A
T
R
D
T
I
F
D
V
P
V
E
R
V
Q
P
F
Y
A
A
L
K
E
F
V
D
L
M
N
S
-----
K
E
S
K
F
T
F
K
M
N
P
G
D
V
I
T
F
DNWR
L
L
H
G
R
R
S
Y
E
A
G
TEIS
R
H
L
E
G
A
Y
A
D
W
D
V
V
M
S
R
L
R
I
L
R
Q
R
V
E--------------------------------------------------------------------------------------------------------------------------------
34
Fugue
37.57
18%
35
- C2 -
2MH3
-
HES1_HUMAN
A:
[26-95]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
P
K
T
A
S
E
H
R
K
-
S
S
K
P
I
M
E
K
-
R
R
R
A
R
I
N
E
S
L
S
Q
L
K
T
L
I
L
D
A
L
K
---------
K
D
S
S
R
H
S
K
L
E
K
A
D
I
L
E
M
T
V
K
H
L
R
N
L
Q
R
A
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
35.03
28%
7
- C2 -
3OHG
7
?
A:
[183-230]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
N
T
H
P
R
T
S
V
G
L
S
Q
D
R
K
T
M
Y
V
F
V
V
D
G
R
R
K
D
S
---------
F
F
A
L
G
L
T
L
P
H
L
A
T
M
M
K
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------