@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu01800: (2016-06-03 )
MTWHEVNDVIVITLPEIFDMNANLGYLTREKNECMYEIENNIITKVIAIGEIRSLVQVSVINNKQMIVQFLNDSRPVEQWKREEIVKYIHEWFDLDNDLTPFYEMAKADPLLKMPARKFYGLRVIGIPDLFEALCWGVLGQQINLAFAYSLKKQFVEAFGDSIEWNGKKYWVFPPYERIARLTPTDLADIKMTVKKSEYIIGIARLMASGELSREKLMKMNFKDAEKNLIKIRGIGPWTANYVLMRCLRFPTAFPIDDVGLIHSIKILRNMNRKPTKDEILEISVPWKEWQSYATFYLWRVLY
Atome Classification :
(20 SA)
------------.......-..10........20........30.......-.---40........50........60.-.......70........80........90........100--....-.....110.......120....--..--.130.......140.......150.......160........170.......180.......190.......200.......---210.......220.......230.......240.......250.......260......---------.270.......280..-..-...290.......300.-------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------MTWHEVN-
D
V
I
V
I
T
L
P
E
IFDMNANLG
Y
L
TREKN
E
C
M
Y
EI-E---N
N
I
I
T
K
V
I
A
I
G
E
I
R
S
L
V
Q
V
S
VIN-
N
K
Q
M
I
V
Q
F
LNDSR
P
V
E
Q
W
K
R
E
E
I
V
K
Y
I
H
E
W
FDLDNDL
T
----
P
F
Y
E
-
M
AKAD
P
L
LKMP
A
R
KFY
G
L
R
V
IG--
I
P
--
D
L
F
E
A
L
C
W
G
V
L
GQQ
I
N
L
A
F
A
Y
S
L
K
K
Q
F
V
E
AFG-D
S
I
E
WN
G
K
K
Y
W
VFP
P
Y
E
R
I
ARLTPTDLA
D
I
K
M
T
V
KKS
E
Y
I
I
G
I
A
R
L
M
AS---GEL
S
R
E
K
L
M
KMNFKDAEK
N
L
I
K
I
RGIGPW
T
A
N
Y
V
L
M
R
C
L
RFPTAFPI
D
D
V
G
L
I
H
S
I
K
I
L
---------
R
NMNRKP
T
K
D
E
I
L
E
I
S-V
P
-
W
K
E
W
Q
S
Y
A
T
F
Y
L
W
R
V
LY-------
21
HHSearch
91.92
24%
-110
- C3 -
2JHN
8
?
A:
[2-286]
----------------------
W
R
I
E
L
K
H
A
V
N
W
E
L
K
M
K
F
F
V
L
P
E
L
P
T
P
D
V
V
-
E
---
S
G
V
W
R
R
A
I
V
L
D
G
R
A
V
A
V
M
A
Y
P
E
S
-
E
R
T
I
V
V
E
G
N
F
-----
E
N
R
E
W
E
A
V
R
R
K
L
V
E
Y
L
G
L
Q
-
N
P
E
----
E
L
Y
R
-
F
M
D
G
D
E
K
L
R
M
L
K
N
R
F
Y
G
F
G
R
A
G
L
M
S
M
--
S
V
F
E
G
I
A
K
A
I
I
Q
Q
Q
I
S
F
V
V
A
E
K
L
A
A
K
I
V
G
R
F
G
-
D
E
V
E
W
N
G
L
K
F
Y
G
F
P
T
Q
E
A
I
L
K
A
G
V
E
G
L
R
E
C
G
L
S
R
R
K
A
E
L
I
V
E
I
A
K
E
E
N
--------
L
E
E
L
K
E
W
G
E
E
E
A
Y
E
Y
L
T
S
F
K
G
I
G
R
W
T
A
E
L
V
L
S
I
A
L
G
K
-
N
V
F
P
A
D
D
L
G
V
R
R
A
V
S
R
L
---------
Y
F
N
G
E
I
Q
S
A
E
K
V
R
E
I
A
R
E
R
-
F
G
R
F
A
R
D
I
L
F
Y
L
F
L
Y
---------
41
Fugue
91.51
24%
-102
- C3 -
2JHN
8
?
A:
[1-295]
---------------------
M
W
R
I
E
L
K
H
A
V
N
W
E
L
K
M
K
F
F
V
L
P
E
L
P
T
P
D
V
V
-
E
---
S
G
V
W
R
R
A
I
V
L
D
G
R
A
V
A
V
M
A
Y
P
E
S
-
E
R
T
I
V
V
E
-----
G
N
F
E
N
R
E
W
E
A
V
R
R
K
L
V
E
Y
L
G
L
Q
N
P
E
E
----
L
Y
R
F
-
M
D
G
-
D
E
K
L
R
M
L
K
N
R
F
Y
G
F
G
R
A
G
--
L
M
SM
S
V
F
E
G
I
A
K
A
I
I
Q
Q
Q
I
S
F
V
V
A
E
K
L
A
A
K
I
V
G
R
F
G
-
D
E
V
E
W
N
G
L
K
F
Y
G
F
P
T
Q
E
A
I
L
K
A
G
V
E
G
L
R
E
C
G
L
S
R
R
K
A
E
L
I
V
E
I
A
K
E
E
N
L
---
E
E
L
K
E
W
-----
G
E
E
E
A
Y
E
Y
L
T
S
F
K
G
I
G
R
W
T
A
E
L
V
L
S
I
A
L
G
-
K
N
V
F
P
A
D
D
L
G
V
R
R
A
V
S
R
L
---------
Y
F
N
G
E
I
Q
S
A
E
K
V
R
E
I
A
-
R
E
R
F
G
R
F
A
R
D
I
L
F
Y
L
F
L
Y
D
R
F
FSKELV
22
HHSearch
90.97
24%
-106
- C3 -
1MPG
1
3MG2_ECOLI
A:
[1-275]
---------------------
M
Y
T
L
N
W
Q
P
P
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
-
A
---
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
T
A
I
P
D
I
A
R
H
T
L
H
I
N
L
S
A
-
G
L
---
E
P
V
A
A
E
C
L
A
K
M
S
R
L
F
D
L
Q
C
N
P
Q
----
I
V
-------
N
G
A
L
G
R
L
G
A
A
R
P
G
L
R
L
P
G
--
C
V
--
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
-
E
R
L
D
D
-
F
P
E
Y
I
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
---
G
T
L
P
M
T
I
--
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
L
I
K
Q
R
F
P
------------
G
----
M
T
P
A
Q
I
R
R
Y
A
-
E
R
-
W
K
P
W
R
S
Y
A
L
L
H
I
W
Y
T
E
--------
8
PsiBlast_PDB
90.39
25%
-97
- C3 -
3CVT
2
3MG2_ECOLI
A:
[10-272]
------------------------------
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
-
A
---
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
-
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
-
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-
L
G
A
A
R
P
----------
G
L
R
L
P
G
--
C
V
--
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
-
E
R
L
D
-
D
F
P
E
Y
I
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
---
G
T
L
P
M
T
--
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
-------
L
I
---------
K
Q
R
F
P
G
M
T
P
A
Q
I
R
R
Y
A
-
E
R
-
W
K
P
W
R
S
Y
A
L
L
H
I
W
-----------
24
HHSearch
90.34
21%
-119
- C3 -
4EJY
3
?
A:
[23-297]
------------------
G
-
T
K
V
I
V
R
G
I
A
D
F
N
L
K
E
T
F
E
S
G
Q
C
F
----
R
W
N
E
E
E
---
D
G
S
Y
T
G
V
A
--
Y
D
--
R
V
V
N
V
K
L
E
G
--
D
T
L
---
I
I
D
-
N
-----
T
N
L
T
D
F
Y
D
I
W
F
D
Y
F
D
L
G
R
D
Y
G
----
Q
I
K
E
-
S
L
S
K
D
P
V
L
K
E
A
I
K
F
G
Q
G
I
R
I
L
R
---
Q
--
D
T
W
E
T
L
V
S
F
I
V
S
Q
N
N
R
I
P
Q
I
K
K
V
I
E
N
L
A
T
S
F
G
-
N
P
I
E
Y
K
G
K
I
Y
Y
T
F
P
K
P
E
E
L
V
M
Y
D
V
E
T
I
A
K
T
R
C
G
F
-
R
A
K
Y
I
F
D
A
A
S
K
V
F
S
---
G
E
I
N
L
L
K
L
H
E
Y
S
T
S
E
I
R
D
I
L
M
T
I
N
G
V
G
P
K
V
A
D
C
V
I
L
Y
S
I
G
R
Y
D
T
F
P
T
-
D
V
W
I
K
R
I
V
E
H
L
---------
Y
L
K
R
E
-
G
T
P
V
E
I
Q
L
F
A
I
D
K
-
F
G
D
L
S
G
F
A
Q
Q
Y
L
F
Y
Y
---------
9
PsiBlast_PDB
89.79
25%
-97
- C3 -
3CW7
2
3MG2_ECOLI
A:
[10-272]
------------------------------
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
-
A
---
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
-
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
-
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-
L
G
A
A
R
P
----------
G
L
R
L
P
G
--
C
V
--
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
-
E
R
L
D
-
D
F
P
E
Y
I
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
---
G
T
L
P
M
T
--
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
-------
L
I
---------
K
Q
R
F
P
G
M
T
P
A
Q
I
R
R
Y
A
-
E
R
-
W
K
P
W
R
S
Y
A
L
L
H
I
W
-----------
14
PsiBlast_PDB
89.65
25%
-95
- C3 -
3D4V
2
3MG2_ECOLI
A:
[10-272]
------------------------------
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
-
A
---
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
-
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
-
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-
L
G
A
A
R
P
----------
G
L
R
L
P
G
--
C
V
--
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
-
E
R
L
D
-
D
F
P
E
Y
I
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
---
G
T
L
P
M
T
--
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
-------
L
I
---------
K
Q
R
F
P
G
M
T
P
A
Q
I
R
R
Y
A
-
E
R
-
W
K
P
W
R
S
Y
A
L
L
H
I
W
-----------
7
PsiBlast_PDB
89.15
25%
-94
- C3 -
3CVS
2
3MG2_ECOLI
A:
[10-272]
------------------------------
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
-
A
---
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
-
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
-
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-
L
G
A
A
R
P
----------
G
L
R
L
P
G
--
C
V
--
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
-
E
R
L
D
-
D
F
P
E
Y
I
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
---
G
T
L
P
M
T
--
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
-------
L
I
---------
K
Q
R
F
P
G
M
T
P
A
Q
I
R
R
Y
A
-
E
R
-
W
K
P
W
R
S
Y
A
L
L
H
I
W
-----------
4
PsiBlast_PDB
89.02
25%
-91
- C3 -
1MPG
1
3MG2_ECOLI
A:
[10-272]
------------------------------
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
-
A
---
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
-
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
-
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-
L
G
A
A
R
P
----------
G
L
R
L
P
G
--
C
V
--
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
-
E
R
L
D
-
D
F
P
E
Y
I
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
---
G
T
L
P
M
T
--
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
-------
L
I
---------
K
Q
R
F
P
G
M
T
P
A
Q
I
R
R
Y
A
-
E
R
-
W
K
P
W
R
S
Y
A
L
L
H
I
W
-----------
13
PsiBlast_PDB
88.90
25%
-95
- C3 -
3CWU
2
3MG2_ECOLI
A:
[10-272]
------------------------------
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
-
A
---
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
-
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
-
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-
L
G
A
A
R
P
----------
G
L
R
L
P
G
--
C
V
--
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
-
E
R
L
D
-
D
F
P
E
Y
I
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
---
G
T
L
P
M
T
--
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
-------
L
I
---------
K
Q
R
F
P
G
M
T
P
A
Q
I
R
R
Y
A
-
E
R
-
W
K
P
W
R
S
Y
A
L
L
H
I
W
-----------
12
PsiBlast_PDB
88.82
25%
-93
- C3 -
3CWT
2
3MG2_ECOLI
A:
[10-272]
------------------------------
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
-
A
---
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
-
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
-
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-
L
G
A
A
R
P
----------
G
L
R
L
P
G
--
C
V
--
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
-
E
R
L
D
-
D
F
P
E
Y
I
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
---
G
T
L
P
M
T
--
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
-------
L
I
---------
K
Q
R
F
P
G
M
T
P
A
Q
I
R
R
Y
A
-
E
R
-
W
K
P
W
R
S
Y
A
L
L
H
I
W
-----------
6
PsiBlast_PDB
88.65
25%
-96
- C3 -
1PVS
1
3MG2_ECOLI
A:
[10-272]
------------------------------
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
-
A
---
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
-
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
-
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-
L
G
A
A
R
P
----------
G
L
R
L
P
G
--
C
V
--
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
-
E
R
L
D
-
D
F
P
E
Y
I
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
---
G
T
L
P
M
T
--
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
-------
L
I
---------
K
Q
R
F
P
G
M
T
P
A
Q
I
R
R
Y
A
-
E
R
-
W
K
P
W
R
S
Y
A
L
L
H
I
W
-----------
10
PsiBlast_PDB
88.36
25%
-96
- C3 -
3CWA
2
3MG2_ECOLI
A:
[10-272]
------------------------------
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
-
A
---
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
-
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
-
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-
L
G
A
A
R
P
----------
G
L
R
L
P
G
--
C
V
--
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
-
E
R
L
D
-
D
F
P
E
Y
I
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
---
G
T
L
P
M
T
--
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
-------
L
I
---------
K
Q
R
F
P
G
M
T
P
A
Q
I
R
R
Y
A
-
E
R
-
W
K
P
W
R
S
Y
A
L
L
H
I
W
-----------
23
HHSearch
87.92
22%
-115
- C3 -
3I0W
8
?
A:
[9-284]
-----------------
K
K
-
D
S
V
I
V
R
N
V
E
N
F
E
L
K
D
I
F
D
C
G
Q
----
C
--
F
R
W
-
H
R
Q
E
N
G
N
Y
-
I
G
I
-
A
F
--
E
K
V
V
E
V
Q
K
I
G
-
E
-
D
--
V
V
I
Y
N
-
I
------
N
E
E
E
F
K
N
V
W
S
E
Y
F
D
L
Y
R
D
Y
G
----
E
I
K
K
-
E
L
S
R
D
P
L
L
K
K
S
V
D
F
G
E
G
I
R
I
L
R
---
Q
--
D
P
F
E
I
L
L
S
F
I
I
S
A
N
N
R
I
P
M
I
K
K
C
I
N
N
I
S
E
K
A
G
-
K
K
L
E
Y
K
G
K
I
Y
Y
A
F
P
T
V
D
K
L
H
E
F
T
E
K
D
F
E
E
C
T
A
-
G
F
R
A
K
Y
L
K
D
T
V
D
R
I
Y
N
---
G
E
L
N
L
E
Y
I
K
S
L
N
D
N
E
C
H
E
E
L
K
K
F
M
G
V
G
P
Q
V
A
D
C
I
M
L
F
S
M
Q
K
Y
S
A
F
P
V
-
D
T
W
V
K
K
A
M
M
S
L
---------
Y
V
A
P
-
D
V
S
L
K
K
I
R
D
F
G
R
E
K
-
F
G
S
L
S
G
F
A
Q
Q
Y
L
F
Y
Y
---------
11
PsiBlast_PDB
87.91
25%
-95
- C3 -
3CWS
2
3MG2_ECOLI
A:
[10-272]
------------------------------
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
-
A
---
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
-
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
-
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-
L
G
A
A
R
P
----------
G
L
R
L
P
G
--
C
V
--
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
-
E
R
L
D
-
D
F
P
E
Y
I
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
---
G
T
L
P
M
T
--
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
-------
L
I
---------
K
Q
R
F
P
G
M
T
P
A
Q
I
R
R
Y
A
-
E
R
-
W
K
P
W
R
S
Y
A
L
L
H
I
W
-----------
2
PsiBlast_PDB
87.57
25%
-96
- C3 -
3OH9
2
3MG2_ECOLI
A:
[17-279]
------------------------------
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
-
A
---
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
-
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
-
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-
L
G
A
A
R
P
----------
G
L
R
L
P
G
--
C
V
--
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
-
E
R
L
D
-
D
F
P
E
Y
I
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
---
G
T
L
P
--
M
T
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
C
-------
L
I
---------
K
Q
R
F
P
G
M
T
P
A
Q
I
R
R
Y
A
-
E
R
-
W
K
P
W
R
S
Y
A
L
L
H
I
W
-----------
1
PsiBlast_PDB
87.39
25%
-98
- C3 -
3OH6
2
3MG2_ECOLI
A:
[17-279]
------------------------------
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
-
A
---
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
-
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
-
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-
L
G
A
A
R
P
----------
G
L
R
L
P
G
--
C
V
--
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
-
E
R
L
D
-
D
F
P
E
Y
I
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
---
G
T
L
P
--
M
T
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
C
-------
L
I
---------
K
Q
R
F
P
G
M
T
P
A
Q
I
R
R
Y
A
-
E
R
-
W
K
P
W
R
S
Y
A
L
L
H
I
W
-----------
3
PsiBlast_PDB
87.20
25%
-95
- C3 -
3OGD
2
3MG2_ECOLI
A:
[17-279]
------------------------------
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
-
A
---
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
-
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
-
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-
L
G
A
A
R
P
----------
G
L
R
L
P
G
--
C
V
--
D
A
F
E
Q
G
V
R
A
I
L
G
Q
C
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
-
E
R
L
D
-
D
F
P
E
Y
I
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
---
G
T
L
P
--
M
T
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
-------
L
I
---------
K
Q
R
F
P
G
M
T
P
A
Q
I
R
R
Y
A
-
E
R
-
W
K
P
W
R
S
Y
A
L
L
H
I
W
-----------
5
PsiBlast_PDB
87.15
25%
-94
- C3 -
1DIZ
3
3MG2_ECOLI
A:
[10-272]
------------------------------
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
-
A
---
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
-
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
-
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-
L
G
A
A
R
P
----------
G
L
R
L
P
G
--
C
V
--
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
-
E
R
L
D
-
D
F
P
E
Y
I
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
---
G
T
L
P
M
T
--
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
-------
L
I
---------
K
Q
R
F
P
G
M
T
P
A
Q
I
R
R
Y
A
-
E
R
-
W
K
P
W
R
S
Y
A
L
L
H
I
W
-----------
43
Fugue
83.02
16%
-101
- C3 -
1EBM
2
OGG1_HUMAN
A:
[1-317]
GSEGHRTLASTP
A
L
W
A
S
I
P
C
P
R
S
E
L
R
L
D
L
V
L
P
S
G
Q
S
F
R
W
R
E
Q
S
P
A
H
W
S
G
V
L
-
A
---
D
----
Q
V
W
T
L
T
Q
T
E
E
Q
L
H
C
T
V
Y
R
-
S
Q
-------------
A
S
R
P
T
P
D
E
L
E
A
V
R
K
Y
F
Q
L
D
V
T
L
A
----
Q
L
Y
H
H
W
G
S
V
D
S
H
F
Q
E
V
A
Q
K
F
Q
G
V
R
L
L
R
---
Q
--
D
P
I
E
C
L
F
S
F
I
C
S
S
N
N
N
I
A
R
I
T
G
M
V
E
R
L
C
Q
A
F
G
P
R
L
I
Q
L
D
D
V
T
Y
H
G
F
P
S
L
Q
A
L
A
G
P
E
V
E
A
H
L
R
K
L
G
L
G
Y
R
A
R
Y
V
S
A
S
A
R
A
I
L
E
EQG
G
L
A
W
L
Q
Q
L
R
E
S
S
Y
E
E
A
H
K
A
L
C
I
L
P
G
V
G
T
Q
V
A
D
C
I
C
L
M
A
L
D
K
P
Q
A
V
P
V
D
V
H
M
W
H
I
A
Q
R
D
Y
S
W
H
P
T
TSQA
K
G
P
S
P
Q
T
N
K
E
L
G
N
F
F
R
-
S
L
-
W
G
P
Y
A
G
W
A
Q
A
V
L
F
S
A
D
L
R
Q-----