@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu01935: (2016-06-03 )
MNSLSLVFWSILAVVGLLLFIKFKPPTIASLLLSKDEAKEISIQFIKEFVGIDVENWDFYSVYWYDHDTVNKLHHLGILKKNRKVLYDVGLVESWRVRFVHQNQSFVVGVNANREITFFYADVPKKTLSGKFEQVSPETLKQRLMASPDGLWSRANMTGTGKKEEDFREVSTYWYIAEAGDIRLKVTVELQGGRISYIGTEQEILTDQMSKVIRDEQVESTFGVSGMLGSALAMILAILILVFMDVQTSIIFSLVLGLLIIICQSLTLKEDIQLTIVNAYDARMSVKTVSLLGILSTLLTGLLTGFVVFICSLAGNALAGDFGWKTFEQPIVQIFYGIGAGLISLGVTSLLFNLLEKKQYLRISPELSNRTVFLSGFTFRQGLNMSIQSSIGEEVIYRLLMIPVIWWMSGNILISIIVSSFLWAVMHQVTGYDPRWIRWLHLFIFGCFLGVLFIKFGFICVLVAHFIHNLVLVCMPLWQFKLQKHMHHDQPKHTSL
Atome Classification :
(18 SA)
---.........10..------------......20...--.....30........40.....--...50.--.......60..-...-----...70........80.....-...90------.........100---.----..-..------..110-------.-----......-----..120.......130.....-..140.......-150......-.160.......170------......--.------..--180.......--.190.....---------------..200......--.210.......220---.......230...----....240..-------------.....250.......260.......270.......280-----.........290.......300....-----...310...-....320.......330..----.....340.......350---.......360.......370.......380........390.-......400......---.410......----------.420.......430.--------------..--....440-----------........450....-.-..460--.......470----------.........480.....-..490....---
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---MN
S
L
S
L
V
F
W
S
I
L
A
------------
V
V
G
L
L
L
F
I
KFK--P
P
T
I
A
S
L
L
LSKD
E
A
K
E
I
S
I
Q
F
I
--
K
E
F
VGI--DVEN
W
D
F
Y
S
V
Y
-
W
YD-----H
D
T
V
N
K
L
H
H
L
GILKKN
R
K
V
L
-
Y
D
VG-------LVE
S
W
R
V
R
F
V
HQ---N----Q
S
-
F
V
------
V
G
V---------N-----AN
R
E
I
T
-----
F
F
YADVP
K
K
T
LSGKFEQV
S
P
-
E
T
L
K
Q
R
LMASPD-GLWSRANMT-GTGK
K
E
E
D
F
R
E
V
--------
S
T
Y
W
Y
I
--
A
------EA--G-
D
I
R
L
K
V
T
V
--
E
L
QG
G
R
I
S
Y
---------------IG
T
E
Q
E
I
L
T
D
Q
--
M
S
K
V
I
R
D
E
Q
V
E
S
TF---GVS
G
M
L
G
S
A
L
A
M
I
----
L
A
I
L
I
L
V
F
M
-------------
D
V
Q
T
S
I
I
F
S
L
V
L
G
L
L
I
I
I
CQSLTLKE
D
I
Q
L
T
I
V
NAY-------DARMS
V
K
T
V
S
L
L
G
I
L
S
T
L
L
T
G
L
L
T
G
F
-----
V
V
F
I
C
S
LAG-NALAGDFG
W
K
T
F
E
Q
P
I
V
Q
I
----
F
Y
G
I
G
A
G
L
I
S
L
G
V
T
S
L
L
F
---
N
L
L
E
K
K
Q
Y
L
R
ISPELSN
R
T
V
F
LSGFTFR-QGLN
M
S
I
Q
S
S
I
G
E
-
E
V
I
Y
R
L
L
M
I
P
V
I
W
WM---SG
N
I
L
I
S
I
I
V
----------
S
S
F
L
W
A
V
M
H
Q
VTGY
D
--------------
P
R
--
W
I
R
W
L
H
------------
L
F
I
F
G
C
F
L
G
V
L
F
I
K
F
-
G
-
F
I
C
V
L
--
V
A
H
F
I
H
N
L
------------
V
L
V
C
M
P
L
W
Q
F
K
L
Q
K
H
MH-HDQPKHTSL---
20
Fugue
89.99
17%
-111
- C1 -
4ZLA
5
AMPA_HELPY
A:
[7-502]
--------------------------------
M
L
K
I
K
L
E
--
K
T
T
F
------
E
N
A
K
A
E
C
S
L
V
F
I
I
N
K
D
F
S
H
A
--
W
V
K
N
K
E
L
L
E
T
F
-
K
Y
E
GEGVF
L
D
Q
E
N
K
I
L
Y
A
G
V
K
E
D
D
V
H
L
L
-
R
E
S
A
-------
C
L
A
V
R
T
L
K
K
L
-
A
---
F
----
K
S
-
V
K
------
V
G
V
Y
T
C
GAHN
A
L
L
-----
E
N
L
K
A
L
-----
F
L
G
L
K
L
G
L
Y
E
Y
D
T
F
K
S
N
K
K
E
-
S
V
L
K
E
A
I
V
A
L
E
L
-
H
-----------
K
S
L
E
K
S
A
K
E
A
--------
L
K
Y
A
E
I
--
M
------
T
E
--
S
-
L
N
I
V
K
D
L
V
N
T
P
P
M
I
G
T
P
V
Y
---------------
M
A
E
V
A
Q
K
V
A
K
E
N
H
L
E
I
H
V
H
D
E
K
F
L
E
E
K
---
K
M
N
A
F
L
A
V
N
K
A
S
L
SV
N
P
P
R
L
I
H
L
V
Y
K
-------------
P
K
K
A
K
K
K
I
A
L
V
G
K
G
L
T
Y
D
C
G
G
L
S
L
K
P
A
D
Y
M
V
T
M
K
A
D
-------
K
G
G
G
S
A
V
I
G
L
L
N
A
L
A
K
L
G
V
E
A
E
V
H
G
I
-----
I
G
A
T
E
N
M
I
G
P
A
A
Y
K
P
D
D
I
L
I
S
K
E
G
K
S
I
E
V
----
R
N
T
D
A
E
G
R
L
V
L
A
D
C
L
S
Y
A
---
Q
D
L
N
P
D
V
I
V
D
F
A
T
L
T
G
A
C
V
V
G
L
G
E
F
T
S
A
I
M
G
H
N
E
E
L
K
N
L
F
E
T
-
S
G
L
E
S
G
E
L
L
A
K
L
P
F
------
N
R
H
L
K
K
L
I
----------
E
S
K
I
A
D
V
C
N
-
I
S
S
S
R
--------------
Y
G
--
G
A
I
T
A
G
------------
L
F
L
N
E
F
I
R
D
E
F
K
D
K
W
-
L
-
H
I
D
I
A
--
G
P
A
Y
V
E
K
E
WDVNSFGASGAG
V
R
A
C
T
A
F
V
E
E
L
L
K
K
A
---------------
15
Fugue
75.62
16%
-93
* C5 *
4WVM
-
STXA_SYNHO
A:
[4-703]
D
L
V
M
P
A
L
G
R
P
F
T
L
G
M
L
Y
D
ARREKLIS
S
N
A
Q
R
S
S
E
F
K
I
V
A
--
S
D
S
T
E
S
K
S
S
A
M
D
I
E
A
S
L
G
V
S
F
L
--
G
G
L
V
E
V
GG
S
A
K
Y
L
N
N
T
K
K
Y
-
Q
N
Q
-----
S
R
V
T
L
K
Y
K
A
T
T
V
Y
K
Q
F
T
H
V
V
-
T
S
I
L
Y
G
A
N
A
F
F
V
S
D
S
D
K
V
D
I
Q
G
K
---
M
----
E
A
-
A
I
------
K
K
I
PTISILT--
D
-----
E
E
K
S
L
A
S
N
L
S
C
K
F
H
G
D
F
L
L
E
S
L
P
T
T
F
E
D
A
V
K
-
T
Y
Q
T
L
P
T
N
S
V
P
M
-
K
V
W
L
A
P
N
V
S
-
K
V
R
R
I
H
T
T
L
E
E
L
--------
H
K
L
K
R
R
--
A
------
N
E
--
A
M
D
V
K
L
V
Q
R
I
--
P
L
I
H
D
K
I
S
N
F
Q
Q
I
F
Q
D
Y
M
L
T
V
Q
K
K
I
A
E
K
L
P
L
V
R
E
Q
--
S
L
Q
K
I
I
D
D
R
A
Q
S
P
F
S
N
E
K
V
S
K
W
L
D
A
V
E
R
E
I
----
A
V
L
K
S
C
A
G
M
V
EGTQ
A
K
F
V
SN
Q
T
E
L
D
R
E
V
L
V
G
K
V
K
H
A
V
C
F
I
F
T
S
V
E
-
R
N
D
P
Y
L
K
V
L
S
D
Y
W
E
SSTED
K
W
C
F
S
T
E
V
V
L
K
M
Q
Q
R
A
Q
T
F
C
D
H
V
N
D
F
E
KSRN
V
G
F
F
I
T
A
L
E
-
N
G
K
F
Q
G
A
S
I
Y
Y
Y
K
E
G
S
L
A
T
QDFT
F
P
R
M
P
F
V
Q
G
Y
K
K
R
S
D
L
L
W
Y
A
C
D
L
T
F
D
R
N
T
I
N
N
W
I
S
L
S
N
D
T
F
A
A
S
E
H
G
K
R
-
Q
N
Y
P
K
H
P
E
R
F
V
S
F
N
Q
V
L
C
N
E
G
L
M
G
K
H
Y
W
E
V
EW
N
G
Y
I
D
V
G
I
A
Y
ISIPRKIDFA
S
A
F
G
Y
N
T
Y
S
W
V
L
S
Y
N
--------------
P
K
I
G
Y
I
E
R
H
K
K
R
E
Y
N
V
R
A
PNPG
F
K
R
L
G
L
F
L
D
W
R
Y
G
S
I
-
S
-
F
Y
A
V
S
SD
E
V
H
H
L
H
T
F
------------
K
----
T
K
F
T
E
P
V
Y
P
A
F
S
I
G
P
A
G
N
H
G
T
L
R
L
L
5
HHSearch
47.04
12%
-21
- C4 -
5BOI
2
?
A:
[80-181]
----------------------------------------------
K
Q
N
I
S
L
N
D
A
M
N
K
A
T
K
F
L
--
K
D
H
R
-
F
--
E
--
S
L
V
--
M
A
--
E
S
---------------------------
A
Q
---------
Y
D
N
M
G
V
F
T
F
V
E
Q
T
ES
G
VRIY
P
D
S
V
K
------
M
K
M
---------
S
L----
E
D
G
S
V
I
-----
G
F
S
A
K
D
F
L
L
K
H
R
T
-----
R
--
D
I
P
K
P
K
I
S
K
E
Q
A
-
K
T
K
L
N
S
N
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
37.38
7%
1
- C4 -
5BOI
2
?
A:
[42-153]
------------------------------------------------------------------------------------------------------------------------------
Y
E
V
Y
S
L
T
I
T
D
P
---
K
T---
N
Q
E
T
Y
------
M
D
I
---------
T
Q----
K
G
G
Y
P
L
-----
W
V
L
E
D
R
D
I
K
--
K
-------------
Q
N
I
S
L
N
D
A
-
M
N
K
A
T
K
F
L
K
-
D
H
R
F
E
--
S
L
V
M
A
E
S
A
Q
Y
DN
M
G
V
F
T
F
V
--
E
Q
T
ESGV
R
I
--
Y
-
P
D
S
V
K
M
K
M
--
S
L
E
D
G
S
V
I
G
---------------
F
S
A
K
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
Fugue
37.07
18%
22
* C4 *
2LN3
-
?
A:
[1-83]
---------------------------------------------------------------------------------------------------------
M
G
L
T
R
T
I
T
S
Q
N
K
E
-------
E
L
L
E
I
A
L
K
F
I
S
Q
---
G
----
L
D
-
L
E
------
V
E
F
---------
D
STD
D
K
E
I
E
E
F
E
-----
R
D
M
E
D
L
A
K
K
T
G
V
Q
I
Q
K
Q
W
Q
G
-
N
K
L
R
I
R
L
K
G
S
L
E
-
H
H
H
H
H
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
HHSearch
36.54
16%
-122
- C4 -
4CAD
1
RCE1_METMP
C:
[128-238]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
V
L
F
L
L
L
L
A
A
T
F
E
-
E
L
G
W
R
G
Y
A
F
D
S
L
Q
S
R
----
Y
S
L
F
K
A
S
I
L
----------
F
G
I
F
W
S
L
W
H
F
P
L
I
F
V
NNS
Y
Q
Y
E
I
F
N
Q
S
I
W
Y
G
--
L
N
F
F
L
S
------------
I
L
P
M
G
I
I
I
T
W
M
C
L
K
N
R
K
S
I
I
L
A
I
--
I
F
H
F
L
I
N
L
------------
N
Q
E
L
L
A
------------------------
4
HHSearch
36.47
8%
20
- C4 -
4EXR
2
?
A:
[62-171]
-------------------------------------------------------------------------------------------------------------------------------
F
V
Y
T
V
E
G
V
D
D
---
N
----
N
E
-
Y
K
------
M
K
I
---------
D
A----
N
T
K
D
V
L
-----
E
D
K
T
E
K
L
D
S
E
D
L
N
G
V
A
R
K
E
K
-
L
D
L
N
D
I
M
T
P
Q
Q
A
-
M
E
I
A
L
K
E
Q
N
-
G
---
I
V
K
E
W
S
L
D
K
D
L-----
D
V
T
F
Y
K
I
R
I
------
D
K
--
D
-
K
N
E
Y
D
I
K
V
--
D
S
K
K
G
T
V
L
K
---------------
V
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
Fugue
34.82
18%
63
- C4 -
1HYW
-
W_LAMBD
A:
[1-58]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
R
Q
E
E
L
A
A
A
--------
R
A
A
L
H
D
--
L
------
M
T
--
G
---
K
R
V
A
T
V
--
Q
K
D
G
R
R
V
E
F
---------------
T
A
T
S
----
V
S
D
--
L
K
K
Y
I
A
E
L
E
V
Q
--
T
---
G
M
T
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
33.08
7%
-14
- C3 -
4IU3
3
?
B:
[5-240]
-------------------------------------------------------
N
T
V
T
S
A
V
K
--
T
Q
Y
V
E
I
--
E
S
V
D
G
F
Y
F
N
T
E
D
K
F
D
-----
T
A
Q
I
K
K
A
V
L
H
T
V
Y
N
E
G
Y
T
G
D
-
D
G
V
A
-------
V
V
L
R
E
Y
E
S
E
P
V
D
---
I
----
T
A
-
E
L
TFGDAT
P
A
N
---------
T
-----
Y
K
A
V
E
N
-----
K
F
D
Y
E
I
P
V
Y
Y
N
N
A
T
L
K
D
A
E
G
-
N
D
A
T
V
T
V
Y
I
G
L
K
-
G
---
D
T
D
L
N
-
N
I
V
D
G
R
D
A
T
A
T
L
--------
T
Y
Y
A
A
T
--
S
------
T
D
--
G
-
K
D
A
T
T
V
A
L
--
S
P
S
T
L
V
G
G
N
---------------
P
E
S
V
Y
D
D
F
S
A
F
--
L
S
D
V
K
V
D
A
G
K
E
L
T
R
---
F
A
K
K
A
E
R
L
I
D
G
R
D
----
A
S
S
I
L
T
F
Y
T
-------------
K
S
S
V
D
Q
Y
K
D
M
A
A
N
E
P
N
K
L
W
D
I
V
T
G
D
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
31.00
32%
94
- C2 -
4QKS
2
?
A:
[41-110]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
I
S
P
-
E
G
N
G
E
V
L
L
R
S
T
E
T
G
Q
W
L
R
I
N
P
D
-
G
T
V
D
G
T
R
D
R
S
D
P
--------
G
I
Q
W
Q
I
--
S
------
P
E
GN
G
-
E
V
L
L
R
S
T
E
--
T
G
Q
W
L
R
I
N
P
---------------
D
G
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
30.85
13%
74
- C4 -
2N2U
-
?
A:
[1-77]
----------------------------------------------------------------------------------------------------------------------------------
M
V
D
L
K
I
D
---
V
----
S
D
-
D
E
------
E
A
E
---------
K
-----
I
I
R
E
I
R
-----
E
Q
W
P
K
A
T
V
T
R
T
N
G
D
I
K
L
D
A
Q
T
E
K
E
A
E
K
M
E
K
A
V
K
-
K
V
K
P
N
A
T
I
R
-
K
T
G
G
S
L
E
H
H
H
H
H
--------
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
30.46
10%
143
- C4 -
4EXR
-
?
A:
[142-173]
------------------------------------------------------------------------------------------------------------------------------
V
T
F
Y
K
I
R
I
D
K
D
---
K
----
N
E
-
Y
D
------
I
K
V
---------
D
S----
K
K
G
T
V
L
-----
K
V
E
K
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
27.37
18%
98
- C5 -
4UZZ
-
?
B:
[538-602]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
-
S
D
E
F
A
S
E
K
V
-
R
L
A
Q
L
T
N
K
C
N
N
N
--------
D
L
D
Y
Y
I
--
K
------
E
S
--
G
-
D
I
-
L
G
V
T
D
--
K
V
K
N
K
H
--------------------
D
A
K
A
I
L
R
Y
V
--
L
E
E
L
I
N
F
K
K
L
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
18.89
6%
148
- C4 -
2KGY
-
?
A:
[67-99]
-------------------------------------------------------------------------------------------------------------------------------
A
A
Y
G
V
L
V
T
R
P
---
D
----
G
T
R
V
E
------
V
H
L
---------
D
-----
R
D
F
R
V
L
-----
D
T
E
P
A
D
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
18.19
16%
271
- C4 -
2GU3
-
YPMB_BACSU
A:
[105-131]
-------------------------------------------------------------------------------------------------------------------------------
L
L
W
E
V
T
Y
L
D
K
---
E
----
G
Q
Y
S
L
------
S
Y
V
---------
D
F----
T
T
G
K
I
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
6.16
10%
0
- C- -
1AZP
-
A:
[1--24]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
K
V
K
F
K
Y
K
G
E
E
K
E
V
D
T
S
K
I
--------
K
K
V
W
R
V
--
G
------
K
-------
M
V
S
F
T
Y
--
D
D
N
G
-
K
T
G
R
---------------
G
A
V
S
E
K
D
A
P
K
E
--
L
L
D
M
L
A
R
A
E
R
E
K
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
3.77
26%
0
- C- -
3WU2
-
PSBT_THEVL
T:
[10-8]
-----------
F
I
F
A
C
------------
I
I
A
L
F
F
F
A
I
F
F
RE
P
P
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
0.99
15%
305
- C4 -
5A63
-
APH1A_HUMAN
C:
[71-97]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
I
F
G
A
A
V
S
V
L
L
Q
-
E
V
-
F
R
F
A
Y
Y
K
L
L
K
K
A
-----------------------------------------------------------------------------------------------------------------------------------------------------