@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu02010: (2016-06-03 )
MLLFTAVISVPMLLLAVSVLMSVIYDSMFKPMNHGMPFHRSFAYPAMIVVFLISLLLLAFLFSKSIHSLLHKINLLNQTIRHLASDQRVPDKIEVKRADEIGELIKSVNLLIERTTYRELELRQQEEIKKELLQKLRHDINTPLTALRLQLFYLEDQCHGQAVFESLYQQIEYISELTNEFNLYSAETLESSYIVNEEVRLNELLETAVKKWDYLYSMSGIELHYKPADQDVIWMSNTLWMERLFDNIFQNTLRHSKAKKMEVTIEHGDVFIRDDGIGFDRNESSEGLGLKIIEDTCRLLAITYELHTNDNGTGFLFSKE
Atome Classification :
(20 SA)
----------------------.........10........20........30........40...--.....50-----.........60---........70........80........90...-.....100.......110....----------...120.----------------------------------------------------------------------------------------------------------------......---.130.......140......--.150....--...------160----.-........170.......180..-------......190.......200-------.......210.......--220---...--..---.---...230....-...240-------.......250....-..----.---------260--......-----.----..----270-.......------------.-------------------280-------.-------------.----------------....--------------...290......-.-300.......-310-........320-----
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------
M
L
L
F
T
A
V
I
S
V
P
M
L
L
L
A
V
S
V
L
M
S
V
I
Y
D
S
M
F
K
PMNHGMP
F
H
RSFA
Y
--
P
A
M
I
V
V
------
F
L
I
S
L
L
L
L
A
F
L
---
F
S
K
S
I
H
S
L
L
H
K
I
N
L
L
N
Q
T
I
R
H
L
ASDQRVP
D
K
I
E
-VK
R
A
D
E
I
G
E
L
I
K
S
V
N
L
L
I
ERT
T
----------
Y
R
E
L
E
-
L
----------------------------------------------------------------------------------------------------------------
R
Q
Q
E
E
I
---
K
K
E
L
L
Q
K
L
R
H
DINT
P
L
T
A
L
R
--
L
Q
L
F
Y
LED--QCH------
G
------
Q
-
A
V
F
E
S
L
Y
Q
Q
I
E
Y
I
S
E
L
T
N
E-FNL-------Y
S
A
E
TLESSYIVN
E
E
V
R
L
N
-------
E
L
L
E
T
A
V
K
K
W
D
Y
L
Y
SMS--G-----
I
E
L
--
H
Y---K---PADQ
D
V
I
W
MS-
N
T
L
W
M
E
-------
R
L
F
D
N
I
F
Q
N
T
L
R
HS-KA----
K
---------
K
----
M
E
V
T
I
E-----H----G
D
----
V
F
--
I
RDDGIG------------F-------------------D---------R-------------N----------------ESSE--------------GL
G
L
K
I
I
E
DT
C
R
-
L
-
L
A
I
T
Y
E
L
HTN-D-N-G
T
G
F
L
F
SKE-------
31
HHSearch
88.32
19%
-73
- C2 -
4I5S
-
?
A:
[37-432]
-----------------------------------------------------------------------------------------------------
N
N
N
Q
V
K
Q
L
N
A
K
V
R
S
L
-
I
T
G
H
Y
T
D
K
L
K
-
V
E
D
N
S
D
L
S
E
L
V
N
N
V
N
D
L
S
E
V
F
R
----------
L
T
H
E
N
-
L
A
Q
E
K
N
R
L
T
S
I
L
S
YMT
D
G
V
L
A
T
D
RSGKITVIN
D
M
A
Q
K
Q
L
NVTREQALECNILDILDDDSY
T
Y
N
D
L
I
TK
T
P
E
I
V
L
T
RRDEYD
E
F
I
T
L
R
I
R
F
A
L
NRRESGFIS
G
L
I
A
V
L
H
DA
T
E
Q
E
K
E
E
R
E
---
R
R
L
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
V
K
--
S
Y
L
E
A
L
D
D
--
G
A
L
------
T
ESV
A
--
P
-
S
F
I
K
V
S
L
D
E
T
N
R
M
M
R
M
I
T
D
-
L
L
S
-------
L
S
R
-----
S
H
L
D
V
E
L
T
N
F
T
-------
A
F
M
N
Y
I
L
D
R
F
D
Q
I
Q
S
Q
Q
ST-------
E
I
--
I
R
---
D
---
Y
P
D
K
S
V
W
I
E
I
-
D
T
D
K
M
T
-------
Q
V
I
D
N
I
L
N
N
A
I
K
Y
S
-
P
D
----
G
---------
G
K---
V
T
I
T
M
Q
-----
T
T
DT
Q
L
I
----
L
S
--
I
S
D
Q
G
L
G
------------
I
-------------------
P
---------
K
-------------
K
DLPLIFDRFYRVDKAR------------------
G
L
G
L
A
I
A
K
E
I
V
K
-
Q
-
H
K
G
F
I
W
A
N
S
E
-
E
-
G
E
G
S
T
F
T
I
V
L
P
-------
40
HHSearch
84.85
22%
-90
- C2 -
2C2A
2
?
A:
[18-246]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
M
---
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
K
--
A
Y
A
E
T
I
Y
N
--
S
L
G
------
E
LDLSTL
K
-
E
F
L
E
V
I
I
D
Q
S
N
H
L
E
N
L
L
N
E
-
L
L
D
-------
F
S
R
L
E
R
K
S
L
Q
I
N
R
E
K
V
D
L
C
-------
D
L
V
E
S
A
V
N
A
I
K
E
F
A
S
S
H
--
N
-----
V
N
V
--
L
F
---
E
S
--
N
V
P
C
P
V
E
A
Y
I
-
D
P
T
R
I
R
-------
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
-
K
K
----
D
---------
A
P
D
K
Y
V
K
V
I
L
D
E
K
DG-
G
----
V
L
----
I
I
--
V
E
D
N
G
I
G
------------
I
-------------------
P
---------
D
-------------
H
A
K
D
R
I
F
EQFYRVD------
T
--------------
G
L
G
L
A
I
T
K
E
I
V
E
-
L
-
H
G
G
R
I
W
V
E
S
E
-
V
G
K
-
G
S
R
F
F
V
W
I
P
-------
39
HHSearch
84.43
20%
-89
- C2 -
4U7O
1
?
A:
[32-261]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
N
D
---
R
K
Q
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
L
R
--
S
Y
I
E
A
L
S
D
--
G
A
W
------
K
DPEV
A
-
P
-
G
F
L
K
V
T
Q
E
E
T
D
R
M
I
R
M
I
N
E
-
L
L
S
-------
L
S
R
M
D
S
G
T
T
R
V
D
M
E
L
V
N
I
N
-------
E
M
F
N
Y
V
L
D
R
F
D
M
I
L
K
K
D
--
D
NPA
K
Y
Y
T
I
--
K
R
---
E
---
F
T
K
R
D
L
W
V
E
I
-
D
T
D
K
F
T
-------
Q
V
L
D
N
I
M
N
N
A
I
K
Y
S
-
P
D
----
G
---------
G
V
---
V
T
C
R
L
L
E
T
HN-
Q
----
V
I
----
I
S
--
I
S
D
Q
G
L
G
------------
I
-------------------
P
---------
R
-------------
A
DLGHVFDRFFRVDK--
Q
G
G
T
--------------
G
L
G
L
A
I
S
K
E
V
V
Q
-
M
-
L
G
G
R
I
W
V
D
S
V
-
E
-
G
K
G
S
T
F
Y
I
S
L
P
-------
35
HHSearch
79.31
23%
-81
- C2 -
4CTI
-
ENVZ_ECOLI
A:
[279-535]
----------------------------------------------------------------------------------------------------
T
I
T
R
P
I
I
E
L
S
N
T
F
D
K
I
-
A
E
G
N
L
E
A
E
V
P
H
Q
N
R
A
D
E
I
G
I
L
A
K
S
I
E
R
L
R
R
S
L
K
----------
Q
L
------------------------------------------------------------------------------------------------------------------------
A
D
D
---
R
T
L
L
M
A
G
V
S
H
D
L
R
T
P
L
T
R
I
R
--
L
A
T
E
M
M
S
E
--
Q
D
G
---------------
Y
L
A
E
S
I
N
K
D
I
E
E
C
N
A
I
I
E
Q
-
F
I
D
-------
Y
L
R
T
G
Q
---
E
------
D
L
N
-------
A
V
L
G
E
V
I
A
-----------
E
-----
I
E
T
--
A
L
---
Y
-----------
K
M
-
H
P
L
S
I
K
-------
R
A
V
A
N
M
V
V
N
A
A
R
Y
G
-
N
-----
G
---------
W
----
I
K
V
S
S
G
T
E
P-------
A
W
----
F
Q
--
V
E
D
D
G
P
---------------------------------------------------------------------------
S
G
T
--------------
G
L
G
L
A
I
V
Q
R
I
V
D
-
N
-
H
N
G
M
L
E
L
G
--------
L
S
I
R
A
W
L
--------
15
PsiBlast_PDB
76.63
23%
-77
- C2 -
4JAS
2
?
A:
[13-220]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
----------------------------------------------------------------------------------------------------------------
K
R
I
D
R
M
---
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
V
I
K
G
Y
A
E
M
I
Y
-----
N
S
L
------
G
------
E
-
L
D
L
S
T
L
K
E
F
L
E
T
I
I
E
Q
S
N
H
-
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
Q
I
N
R
E
K
V
D
L
C
-------
D
L
V
E
S
A
V
N
A
I
K
E
F
A
S
S
H
--
N
-----
V
N
V
--
L
F
---
E
S
NV
P
C
P
V
E
A
-
Y
I
D
-
P
T
R
I
R
Q
-------
V
L
L
-
N
L
L
N
N
G
V
K
Y
S
-
K
K
DAP
D
K
---------
Y
----
V
K
V
I
L
D
-----
E
----
K
D
G
G
V
L
I
I
--
V
E
D
N
G
I
G
------------
I
-------------------
P
---------
D
-------------
H
----------------
A
K
D
-------------------
R
I
F
E
Q
F
Y
R
-
V
D
S
S
L
T
Y
E
V
P
G
----
T
-
G
L
G
L
A
I
T
K
E
-------
17
PsiBlast_PDB
76.61
24%
-65
- C2 -
4JAV
6
?
A:
[5-220]
----------------------------------------------------------------------------------------------------------------------------------------------------
T
E
----------
S
K
E
L
E
R
L
----------------------------------------------------------------------------------------------------------------
K
R
I
D
R
M
---
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
K
--
A
---
Y
A
E
T
I
Y
N
S
L
------
G
------
E
-
L
D
L
S
T
L
K
E
F
L
E
V
I
I
D
Q
S
N
H
-
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
Q
I
N
R
E
K
V
D
L
C
-------
D
L
V
E
S
A
V
N
A
I
K
E
F
A
S
S
H
--
N
-----
V
N
V
--
L
F
---
E
S
NV
P
C
P
V
E
A
-
Y
I
D
-
P
T
R
I
R
Q
-------
V
L
L
-
N
L
L
N
N
G
V
K
Y
S
-
K
K
DAP
D
K
---------
Y
----
V
K
V
I
L
D
-----
E
----
K
D
G
G
V
L
I
I
--
V
E
D
N
G
I
G
------------
I
-------------------
P
---------
D
-------------
H
----------------
A
K
D
-------------------
R
I
F
E
Q
F
Y
R
-
V
D
S
S
L
T
Y
E
V
P
G
----
T
-
G
L
G
L
A
I
T
K
E
-------
16
PsiBlast_PDB
75.92
24%
-67
- C2 -
3DGE
3
?
A:
[14-220]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
R
I
D
R
M
---
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
K
--
A
---
Y
A
E
T
I
Y
N
S
L
------
G
------
E
-
L
D
L
S
T
L
K
E
F
L
E
V
I
I
D
Q
S
N
H
-
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
Q
I
N
R
E
K
V
D
L
C
-------
D
L
V
E
S
A
V
N
A
I
K
E
F
A
S
S
H
--
N
-----
V
N
V
--
L
F
---
E
S
NV
P
C
P
V
E
A
-
Y
I
D
-
P
T
R
I
R
Q
-------
V
L
L
-
N
L
L
N
N
G
V
K
Y
S
-
K
K
DAPD
K
---------
Y
----
V
K
V
I
L
D
-----
E
----
K
D
G
G
V
L
I
I
--
V
E
D
N
G
I
G
------------
I
-------------------
P
---------
D
-------------
H
----------------
A
K
D
-------------------
R
I
F
E
Q
F
Y
R
-
V
D
S
S
L
T
Y
E
V
P
G
----
T
-
G
L
G
L
A
I
T
K
E
-------
32
HHSearch
75.03
18%
-65
- C2 -
4BIX
3
CPXA_ECOLI
A:
[61-293]
----------------------------------------------------------------------------------------------------------------------------------------
A
A
G
A
S
F
N
Q
V
V
T
A
L
E
----------
R
M
M
------------------------------------------------------------------------------------------------------------------------
T
S
---
Q
Q
R
L
L
S
D
I
S
H
E
L
R
T
P
L
T
R
L
Q
--
L
G
T
A
L
L
R
R
--
R
S
G
------
E
------
S
-
K
E
L
E
R
I
E
T
E
A
Q
R
L
D
S
M
I
N
D
-
L
L
V
-------
M
S
R
N
Q
Q
K
N
-
A
L
V
S
E
T
I
K
A
N
-------
Q
L
W
S
E
V
L
D
N
A
A
F
E
A
E
Q
M
--
G
-----
K
S
L
--
T
V
---
N
---
F
P
P
G
P
W
P
L
Y
G
-
N
P
N
A
L
E
-------
S
A
L
E
N
I
V
R
N
A
L
R
Y
S
-
H
T
----
K
---------
I
E
---
V
G
F
A
V
D
-----
K
D
G
--
I
T
----
I
T
--
V
D
D
D
G
P
G
------------
V
-------------------
S
---------
P
-------------
E
DREQIFRPFYRTD-----
G
T
--------------
G
L
G
L
A
I
V
E
T
A
I
Q
-
Q
-
H
R
G
W
V
K
A
E
D
S
-
P
L
G
-
G
L
R
L
V
I
W
L
P
-------
23
Fugue
74.22
16%
-76
- C2 -
4I5S
-
?
A:
[37-432]
N
N
N
Q
V
K
Q
L
N
A
K
V
R
S
L
I
T
G
H
Y
T
D
K
L
K
V
E
D
N
S
D
L
S
E
L
V
N
N
V
N
D
L
S
E
V
F
R
L
T
H
E
N
L
A
Q
E
K
N
R
L
T
S
I
L
S
Y
MT
D
G
V
L
A
T
D
RSGKI
T
V
I
N
D
M
A
Q
K
Q
L
NVT
R
E
Q
A
L
E
C
N
I
L
D
I
L
D
D
D
S
Y
T
Y
N
D
L
I
T
K
T
P
E
I
V
L
T
-
R
R
D
E
Y
D
E
F
I
T
L
R
I
R
F
A
L
N
R
R
E
S
GFIS
G
L
I
A
V
L
H
D
A
T
E
-
Q
----------------------------------------------------------------------------------------------------------------
E
K
E
E
R
E
---
R
R
L
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
V
K
--
S
Y
L
E
A
L
D
D
--
G
A
L
------
T
------
E
-
S
V
A
P
S
F
I
K
V
S
L
D
E
T
N
R
M
M
R
-
M
-
I
-------
T
D
L
L
S
L
S
R
S
H
L
D
V
E
L
T
N
F
T
-------
A
F
M
N
Y
I
L
D
R
F
D
Q
I
Q
S
Q
Q
--
S
-----
T
E
I
--
I
R
---
D
---
Y
P
D
K
S
V
W
I
E
I
-
D
T
D
K
M
T
-------
Q
V
I
D
N
I
L
N
N
A
I
K
Y
S
-
P
D
----
G
G--------
K
----
V
T
I
T
M
Q
-----
T
----
T
D
T
Q
L
I
L
S
--
I
S
D
Q
G
L
G
IPKKDLPLIFDR
F
-------------------
Y
---------
R
-------------
V
----------------
D
K
A
R
--------------
G
L
G
L
A
I
A
K
E
I
V
K
-
Q
-
H
K
G
F
I
W
A
N
S
E
-
E
-
G
E
G
S
T
F
T
I
V
L
P
-------
36
HHSearch
71.93
15%
-71
- C2 -
4Q20
-
DIVL_CAUCR
A:
[535-755]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
E
A
E
R
L
---
K
R
D
F
V
G
N
V
S
Y
E
L
R
T
P
L
T
T
I
I
--
G
Y
S
E
L
L
E
R
--
A
D
--------S
E
R
G
--
R
-
N
H
V
A
A
V
R
A
A
A
T
Q
L
A
R
S
I
D
D
-
V
L
D
-------
M
A
Q
I
D
A
G
E
M
A
L
E
I
E
D
I
R
V
S
-------
D
L
L
L
N
A
Q
E
R
A
L
K
D
A
Q
L
G
--
G
-----
V
T
L
--
A
V
---
E
---
C
E
E
D
V
G
L
I
R
G
-
D
G
K
R
L
A
-------
Q
T
L
D
H
L
V
E
N
A
L
R
Q
T
-
P
P
----
G
---------
G
R
---
V
T
L
S
A
R
-----
R
A
LG
E
V
R
----
L
D
--
V
S
D
T
G
R
G
------------
V
-------------------
P
---------
F
HVQAHIFDRFVGR
D
----------------
R
G
G
P
--------------
G
L
G
L
A
L
V
K
A
L
V
E
-
L
-
H
G
G
W
V
A
L
E
S
E
-
P
-
G
N
G
S
T
F
T
C
H
L
P
-------
13
PsiBlast_PDB
68.49
20%
-60
- C2 -
4U7O
1
?
A:
[25-241]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
----------------------------------------------------------------------------------------------------------------
T
E
Q
Q
K
I
D
N
D
R
K
Q
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
L
R
--
S
Y
I
E
A
L
S
D
--
G
A
W
KDPEV-
A
------
P
-
G
F
L
K
V
T
Q
E
E
T
D
R
M
I
R
M
I
N
E
-
L
L
S
-------
L
S
R
M
D
S
G
T
T
R
V
D
M
E
L
V
N
I
N
-------
E
M
F
N
Y
V
L
D
R
F
D
M
I
L
K
K
D
--
D
-----
N
P
A
--
K
Y
---
Y
---
T
I
K
R
E
--
F
T
K
-
R
D
L
W
V
E
I
D
T
D
K
F
T
Q
V
L
D
N
I
M
N
N
A
I
K
Y
S
-
P
D
----
G
---------
G
----
V
-
V
T
C
R
L
L
E
T
-
H
----
N
Q
----
V
I
I
S
I
S
D
Q
G
L
G
IPRADLGHV---
F
-------------------
D
RFFRVDK---------------------------------
Q
G
G
T
--------------
G
L
G
L
A
I
S
K
E
V
V
Q
-
M
-
L
G
-----------------------------
49
HHSearch
67.88
16%
-67
- C2 -
4R39
2
LVHK2_ERYLH
A:
[18-217]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
---
L
D
R
Q
L
A
E
V
Q
H
R
V
K
N
H
L
A
M
I
V
--
S
M
I
R
I
Q
S
S
--
Q
A
G
------
G
------
V
G
S
Q
F
D
S
L
S
R
R
V
E
A
L
Q
L
L
Y
Q
E
-
M
D
I
-------
A
G
A
-----
A
K
A
T
D
K
I
I
P
L
G
-------
A
Y
L
G
R
I
A
S
A
I
N
H
I
D
G
R
G
--
A
-----
I
K
V
--
N
V
---
Q
---
A
D
-
T
V
D
V
P
V
E
-
T
A
G
R
I
G
-------
L
L
V
S
E
V
L
T
N
A
L
Q
H
A
-
F
S
----
D
RA
S
G
-----
V
----
V
Q
L
R
S
S
V
M
S
GE
Q
----
L
R
----
V
T
--
V
E
D
D
G
R
G
------------
I
-------------------
P
---------
E
-------------
D
CDW-------------
P
N
E
G
--------------
N
L
G
S
R
I
V
R
Q
L
V
Q
-
G
-
L
G
A
E
L
N
V
T
R
G
-
G
-
T
-
G
T
I
V
N
I
D
I
P
-------
14
PsiBlast_PDB
67.77
22%
-85
- C2 -
3JZ3
-
QSEC_ECOLI
A:
[40-208]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
L
Q
-
L
H
-
G
I
D
R
A
T
R
L
V
D
Q
L
L
T
L
-------
S
R
L
D
S
L
D
N
L
Q
D
V
-
A
E
I
P
L
E
-------
D
L
L
Q
S
S
V
M
D
I
Y
H
T
A
Q
Q
A
--
K
-----
I
D
V
--
R
L
---
T
---
L
N
A
H
S
I
K
R
T
G
-
Q
P
L
L
L
S
-------
L
L
V
R
N
L
L
D
N
A
V
R
Y
S
P
Q
G
----
S
---------
V
----
V
D
V
T
L
N
-----
A
----
D
N
----
F
I
--
V
R
D
N
G
P
---------------------------------------------------------------------------------------------
L
G
L
S
I
V
Q
R
I
A
K
-
L
-
H
G
M
N
V
E
F
G
N
A
-
E
-
Q
-
G
-
G
F
------------
47
HHSearch
67.39
18%
-72
- C2 -
4GCZ
5
FIXL_BRADU (first)
A:
[152-370]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
E
M
A
S
A
L
A
H
E
L
N
Q
P
L
A
A
I
S
--
N
Y
M
K
G
S
R
R
--
L
L
A
GSSDPN
T
P
K
V
---
E
-
S
A
L
D
R
A
A
E
Q
A
L
R
A
G
Q
I
I
R
R
-
L
R
D
-------
F
V
A
R
G
E
----
S
E
K
R
V
E
S
L
S
-------
K
L
I
E
E
A
G
A
L
G
L
A
G
A
R
E
Q
--
N
-----
V
Q
L
--
R
F
---
S
---
L
D
P
G
A
D
L
V
L
A
-
D
R
V
Q
I
Q
-------
Q
V
L
V
N
L
F
R
N
A
L
E
A
M
-
A
Q
----
S
---------
Q
R
R
E
-
L
V
V
T
N
T
P
A
A
DD
M
----
I
E
----
V
E
--
V
S
D
T
G
S
G
------------
F
-------------------
Q
---------
D
-------------
D
VIPNLFQTFFTTK---
D
T
G
M
--------------
G
V
G
L
S
I
S
R
S
I
I
E
-
A
-
H
G
G
R
M
W
A
E
S
N
-
A
-
S
G
G
A
T
F
R
F
T
L
P
-------
2
PsiBlast_PDB
67.11
22%
-67
- C2 -
4BIV
2
CPXA_ECOLI
A:
[80-266]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
Q
R
L
L
S
D
I
S
H
E
L
R
T
P
L
T
R
L
Q
--
L
G
T
A
L
L
R
R
--
R
S
G
------
E
------
S
-
K
E
L
E
R
I
E
T
E
A
Q
R
L
D
S
M
I
N
D
-
L
-
L
-------
V
M
S
R
N
Q
Q
K
N
A
L
V
S
E
T
I
K
A
N
-------
Q
L
W
S
E
V
L
D
N
A
A
F
E
A
E
Q
M
--
G
-----
K
S
L
T
V
N
F
---
P
---
P
G
P
W
P
L
Y
G
N
P
-
N
A
L
--
E
-------
S
A
L
E
N
I
V
R
N
A
L
R
Y
S
-
H
T
----
K
I
E
V
------
G
----
F
A
V
D
K
D
-----
G
----
I
T
----
I
T
--
V
D
D
D
G
P
G
------------
V
SPED
R
E
Q
I
F
RPFYRTDEAR
D
---------
R
-------------
E
----------------
S
G
G
T
--------------
G
L
G
L
A
I
V
E
--------------------------------------
37
HHSearch
66.87
17%
-81
- C2 -
3A0R
1
?
A:
[131-343]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
---
L
G
E
M
T
A
R
V
A
H
E
I
R
N
P
I
T
I
I
G
--
G
F
I
M
R
M
K
K
--
H
L
D
------
D
PETL--
K
-
K
Y
I
N
I
I
T
N
E
L
S
R
L
E
T
I
V
K
E
-
I
L
E
-------
Y
S
K
E
R
----
V
L
E
F
T
E
F
N
L
N
-------
E
L
I
R
E
V
Y
V
L
F
E
E
K
I
R
K
M
--
N
-----
I
D
F
--
C
F
---
E
---
T
D
N
E
D
L
R
V
E
A
-
D
R
T
R
I
K
-------
Q
V
L
I
N
L
V
Q
N
A
I
E
A
T
-
G
E
----
N
---------
G
K
---
I
K
I
T
S
E
-----
D
M
YT
K
V
R
----
V
S
--
V
W
N
S
G
P
P
------------
I
-------------------
P
---------
E
ELKEKIFSPFFTT------------------------------------
L
G
L
S
I
C
R
K
I
I
E
D
E
-
H
G
G
K
I
W
T
E
N
R
-
E
-
N
-
G
V
V
F
I
F
E
I
P
-------
18
PsiBlast_PDB
66.20
21%
-77
- C2 -
4I5S
-
?
A:
[211-409]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
V
K
--
S
Y
L
E
A
L
D
D
--
G
A
L
------
T
------
E
-
S
V
A
P
S
F
---
I
K
V
S
L
D
E
T
N
R
-
M
M
R
-------
M
I
T
D
L
L
S
L
S
R
-----
S
H
L
D
V
E
L
T
N
F
T
A
F
M
N
Y
I
L
D
R
F
D
Q
I
Q
S
Q
Q
--
S
-----
T
------E
I
I
R
---
D
Y
P
D
K
S
V
W
I
E
I
D
T
D
K
M
T
-------
Q
V
I
D
N
I
L
N
N
A
I
K
Y
S
P
D
G
----
G
---------
K
----
V
T
I
T
M
Q
-----
T
----
T
D
T
Q
L
I
L
S
--
I
S
D
Q
G
L
G
IPKKDLPLI---
F
-------------------
D
RFYRVDKAR-------------------------------------------------
G
L
G
L
A
I
A
K
E
I
V
K
----------------------------------
3
PsiBlast_PDB
65.79
22%
-62
- C2 -
4CB0
5
CPXA_ECOLI
A:
[80-266]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
Q
R
L
L
S
D
I
S
H
E
L
R
T
P
L
T
R
L
Q
--
L
G
T
A
L
L
R
R
--
R
S
G
------
E
------
S
-
K
E
L
E
R
I
E
T
E
A
Q
R
L
D
S
M
I
N
D
-
L
-
L
-------
V
M
S
R
N
Q
Q
K
N
A
L
V
S
E
T
I
K
A
N
-------
Q
L
W
S
E
V
L
D
N
A
A
F
E
A
E
Q
M
--
G
-----
K
S
L
T
V
N
F
---
P
---
P
G
P
W
P
L
Y
G
N
P
-
N
A
L
--
E
-------
S
A
L
E
N
I
V
R
N
A
L
R
Y
S
-
H
T
----
K
I
E
V
------
G
----
F
A
V
D
K
D
-----
G
----
I
T
----
I
T
--
V
D
D
D
G
P
G
------------
V
SPEDREQIFRPFYRT
D
E
A
R
D
---------
R
-------------
E
----------------
S
G
G
T
--------------
G
L
G
L
A
I
V
E
--------------------------------------
24
Fugue
65.06
13%
-73
- C2 -
1GKZ
8
BCKD_RAT
A:
[38-378]
---------------VRLTPT
M
M
L
Y
S
G
R
S
Q
D
G
S
H
L
L
K
S
G
R
Y
L
Q
Q
E
L
P
V
R
I
A
H
R
I
K
G
F
R
S
L
P
F
I
I
G
--------------------------------
C
N
P
T
I
L
H
V
H
E
L
Y
I
R
A
F
Q
K
L
T
D
F
P
P
I
K
D
Q
A
D
-
E
A
Q
Y
C
Q
L
V
R
Q
L
L
D
D
H
K
D
V
V
T
L
L
----------
A
E
G
L
R
-
E
----------------------------------------------------------------------------------------------------------------
S
R
K
H
I
E
---
D
E
K
L
V
R
Y
F
L
D
K
T
L
T
S
R
L
G
I
R
--
M
L
A
T
H
H
L
A
--
L
H
E
------
D
------
K
-
P
D
F
V
G
I
I
C
T
R
L
S
P
K
K
I
I
E
K
-
W
V
D
-------
F
A
R
R
L
C
E
H
K
Y
G
N
A
P
R
V
R
I
N
-------
G
H
V
A
A
R
F
P
F
I
P
-----------------------------------------
M
P
L
D
-------
Y
I
L
P
E
L
L
K
N
A
M
R
A
T
-
M
E
----
S
H
LDTPY
N
V
P
D
----
V
V
I
T
I
A
-----
N
----
N
D
V
D
L
I
I
R
--
I
S
D
R
G
G
G
------------
I
-------------------
A
---------
H
-------------
K
----------------
D
L
D
R
VMDYHFTTAPMHGF
G
F
G
L
P
T
S
R
A
Y
A
E
-
Y
-
L
G
G
S
L
Q
L
Q
S
L
Q
G
-
I
-
G
T
D
V
Y
L
R
L
R
H
IDGREE
1
PsiBlast_PDB
64.93
22%
-56
- C2 -
4BIW
4
CPXA_ECOLI
A:
[80-266]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
Q
R
L
L
S
D
I
S
H
E
L
R
T
P
L
T
R
L
Q
--
L
G
T
A
L
L
R
R
--
R
S
G
------
E
------
S
-
K
E
L
E
R
I
E
T
E
A
Q
R
L
D
S
M
I
N
D
-
L
-
L
-------
V
M
S
R
N
Q
Q
K
N
A
L
V
S
E
T
I
K
A
N
-------
Q
L
W
S
E
V
L
D
N
A
A
F
E
A
E
Q
M
--
G
-----
K
S
L
T
V
N
F
---
P
---
P
G
P
W
P
L
Y
G
N
P
-
N
A
L
--
E
-------
S
A
L
E
N
I
V
R
N
A
L
R
Y
S
-
H
T
----
K
I
E
V
------
G
----
F
A
V
D
K
D
-----
G
----
I
T
----
I
T
--
V
D
D
D
G
P
G
------------
V
SPEDREQIFRPFYRT
D
E
A
R
D
---------
R
-------------
E
----------------
S
G
G
T
--------------
G
L
G
L
A
I
V
E
--------------------------------------