@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu02310: (2016-06-03 )
MKRMIVRMTLPLLIVCLAFSSFSASARAASEEKYWDHWIERHAQPLDASNASNKDLRFLKKVLKGKRIVQLGETTHGAGEINATKVRMIKYLHEELGYDVLAFESGFPDTNASYLNMDQLTPKSTMKNSIYAVWHTEDVVELFDYMKEQKEKGDPLILTGFDIQSMKNSFNVAATQWVKAVDPEKAELLSQSENDFSTLVTDSNTFDEFSQKKEKLVKNYQKLIKFTKTHASELKENLPKEPKAYEMFMHSLQLRIDVMETYMLEEMKEKLEEYPENIEDFSFFMRDRMMAEQFQWVADTLYPKKKIIVWGHNYHLRKQNTKMIKDWVQLNGPNMGDYLPERLKKQTYTIGIYAYSGASLDSSDNKTVKPVTSPPPSGSLEALLKAADRPAVFVDFLHTKNKKGTSWMYTPRTALYWGYMEEQMILKEQYDGVIWLEHITPSVIIK
Atome Classification :
(20 SA)
------------------------------------------------------.........10........20.......-.-------30.-----------------.......40......--..50-....---.....60-......---...----70........80........90-----------------------.--....-----...100......--.110.......120.----........130..-----...-..140......-----------------------.150---.......160--....----....170...------....180.....----..190......-----------------------.200-.......-..210.......220.......230--.......240.....---..250-----.......260.......270.--------------..---...----.280.......290.......300.......310--.......---------..320.......330-.....-....340.......350...---.....360.-..--....370.......380....-...390-------.........400.--......410----.......420-------........430--------.......440......-----------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------------------------------------MK
R
M
I
V
R
M
T
L
P
L
L
I
V
C
L
A
F
S
SFSASARA-A-------S
E
E
-----------------
K
Y
W
D
H
W
I
E
RHAQPLD--ASN--ASN
K
---
D
L
R
F
L
K
--
K
V
LKG
K
---
R
I
V
----
Q
LGETTHGAGEI
N
A
T
K
V
R
M
I
K
Y
-----------------------
L
--
H
E
E
L-----GY
D
V
L
A
FESGFP--DTNA
S
Y
L
NMDQL--T----
P
K
S
TMKN
S
I
Y
A
V
W-----H
T
E
-
D
V
V
E
L
F
D
Y
M
K
E
-----------------------
Q
KEK---GD
P
L
I
L
T
GF---
D
I
Q
S
----
M
K
NSF
N
V
A
A
T
------
Q
W
V
KAVDP
E
K
A
E
----
L
L
SQSENDF
S
T
-----------------------
L
V---TDSN
T
F
D
-
E
F
S
Q
K
K
E
K
L
V
K
N
Y
Q
K
L
I
K
F
T
K
T
H
A
S
--
E
L
K
E
NLPKE
P
K
A
Y
E
M
---
F
M
H
S
L
-----
Q
L
R
I
D
V
M
E
T
Y
M
L
E
E
M
K
E
K
L
E
E--------------YP---E
N
I
----
E
D
F
S
F
F
M
R
D
R
M
M
A
E
Q
F
Q
W
V
A
D
TLYPK
K
K
I
I
V
W----GH
N
Y
H
L
R---------KQ
N
T
K
M
I
K
D
W
V
QL---NGPN
M
-
G
D
Y
L
P
E
R
L
KKQ
T
Y
T
I
G
-
I
Y
A
---YSGASLDSS-DN--KTVKPVTSPPPS
G
S
L
E
A
L
L
K
A-ADR
P
---------
A
V
F
V
D
F
L
HTKNKK--GT
S
W
M
YTPR----T
A
L
Y
W
G
Y
M
E
--------
E
Q
M
I
L
K
E
QYD
G
--------
V
I
W
L
EHIT--PS
V
I
IK-----------
22
HHSearch
83.70
24%
-71
- C7 -
3B55
1
?
A:
[36-442]
-----------------------------------------------------------------------------------
P
-------
Y
N
T
-----------------
N
Q
I
A
K
W
L
E
A
H
A
K
P
L
K
TT
N
P
T
--
A
S
L
N
---
D
L
K
P
L
K
--
N
M
V
G
S
A
---
S
I
V
----
G
L
G
E
A
T
H
G
A
H
E
V
F
T
M
K
H
R
I
V
K
Y
-----------------------
L
--
V
S
E
K
-----
G
F
T
N
L
V
L
E
E
G
W
D
--
R
A
L
E
L
D
R
Y
V
L
T
G
KG
N
----
P
S
Q
H
L
----
T
P
V
F
-----
K
T
K
-
E
M
L
D
L
L
D
W
I
R
Q
-----------------------
Y
N
A
N
PKH
K
S
K
V
R
V
I
G
M
---
D
I
Q
S
----
V
N
E
N
V
Y
N
N
I
I
------
E
Y
I
K
A
N
N
S
K
L
L
P
----
R
V
E
E
K
I
K
G
L
I
P
-----------------------
V
T
---
K
D
M
N
T
F
E
S
L
T
K
E
E
K
E
K
Y
V
L
D
A
K
T
I
S
A
L
L
E
---
E
--
N
-
K
S
Y
L
N
G
K
S
K
E
F
A
W
---
I
K
Q
N
A
-----
R
I
I
E
-
Q
F
T
T
M
L
--------
A
T
--------------
P
P
---
D
K
P
-----
A
D
F
Y
L
K
H
D
I
A
M
Y
E
N
A
K
W
T
E
E
H
L
---
G
K
T
I
V
W
----
G
H
N
G
H
V
S
---------
K
T
N
M
L
S
F
-----
I
---
Y
P
K
V
A
-
G
Q
H
L
A
E
Y
Y
G
K
R
Y
V
S
I
G
-
T
S
V
---
Y
E
G
Q
Y
N
V
K
N
S
D
G
EF
G
P
Y
G
T
L
K
S
D
D
P
N
-
S
Y
N
Y
I
F
G
Q
-
V
K
K
D
---------
Q
F
F
I
D
L
R
K
A
N
G
-
V
--
T
K
T
W
L
N
E
Q
H
----
P
-
I
F
A
G
I
T
T
EGPDIPK
T
V
D
I
S
L
G
K
A
F
D
I
--------
L
V
Q
I
Q
K
V
S
--
P
S
Q
V
H
------------
1
PsiBlast_PDB
78.21
30%
-73
- C7 -
2RAD
-
?
A:
[45-346]
--------------------------------------------------------------------------------------------------------------------
W
L
E
A
H
A
K
P
L
K
--
T
T
N
PT
A
S
L
N
---
D
L
K
P
L
K
--
N
M
V
G
S
A
---
S
I
V
----
G
L
G
E
A
T
H
G
A
H
E
V
F
T
M
K
H
R
I
V
K
Y
-----------------------
L
--
V
S
E
K
-----
G
F
T
N
L
V
L
E
E
G
W
----
D
R
A
L
E
L
D
R
Y
V
L
--
T
----
G
K
G
N
P
S
Q
H
L
T
P
V
F
-----
K
T
K
-
E
M
L
D
L
L
D
W
I
R
Q
Y
N
A
N-------------------
P
K
H
K
---
S
K
V
R
V
I
-
G
M
---
D
I
Q
S
----
V
N
E
N
V
Y
N
N
I
I
------
E
Y
I
K
A
---
N
N
S
K
----
L
L
P
R
V
E
E
K
I
K
G
-----------------------
L
I
PVT
K
D
M
N
T
F
E
-
S
L
T
-
K
E
E
K
-----
E
K
Y
V
L
D
A
K
T
I
S
A
--
L
L
E
E
N
-----
K
S
Y
-
L
---
N
G
K
S
K
-----
E
F
A
W
I
K
Q
N
A
R
I
I
E
Q
F
T
T
M
L
A
T
--------------
P
P
---
D
K
P
----
A
D
F
-
Y
L
K
H
D
I
A
M
Y
E
N
A
K
W
T
E
E
H
L
---
G
K
T
I
V
W
----
G
H
N
G
H
V
S
---------
K
T
N
M
------
L
S
F
---
I
Y
P
K
V
A
G
Q
H
L
A
E
Y
Y
G
K
R
Y
V
S
I
G
-
T
S
V
---
Y
E
G
-----------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
77.96
30%
-74
- C7 -
3B55
1
?
A:
[45-346]
--------------------------------------------------------------------------------------------------------------------
W
L
E
A
H
A
K
P
L
K
--
T
T
N
PT
A
S
L
N
---
D
L
K
P
L
K
--
N
M
V
G
S
A
---
S
I
V
----
G
L
G
E
A
T
H
G
A
H
E
V
F
T
M
K
H
R
I
V
K
Y
-----------------------
L
--
V
S
E
K
-----
G
F
T
N
L
V
L
E
E
G
W
----
D
R
A
L
E
L
D
R
Y
V
L
--
T
----
G
K
G
N
P
S
Q
H
L
T
P
V
F
-----
K
T
K
-
E
M
L
D
L
L
D
W
I
R
Q
Y
N
A
N-------------------
P
K
H
K
---
S
K
V
R
V
I
-
G
M
---
D
I
Q
S
----
V
N
E
N
V
Y
N
N
I
I
------
E
Y
I
K
A
---
N
N
S
K
----
L
L
P
R
V
E
E
K
I
K
G
-----------------------
L
I
P
V
T
K
D
M
N
T
F
E
-
S
L
T
-
K
E
E
K
-----
E
K
Y
V
L
D
A
K
T
I
S
A
--
L
L
E
E
N
-----
K
S
Y
-
L
---
N
G
K
S
K
-----
E
F
A
W
I
K
Q
N
A
R
I
I
E
Q
F
T
T
M
L
A
T
--------------
P
P
---
D
K
P
----
A
D
F
-
Y
L
K
H
D
I
A
M
Y
E
N
A
K
W
T
E
E
H
L
---
G
K
T
I
V
W
----
G
H
N
G
H
V
S
---------
K
T
N
M
------
L
S
F
---
I
Y
P
K
V
A
G
Q
H
L
A
E
Y
Y
G
K
R
Y
V
S
I
G
-
T
S
V
---
Y
E
G
-----------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
51.12
23%
-30
- C7 -
4C5W
4
BODG_HUMAN
A:
[95-279]
--------------------------------------------------------------------------
C
F
S
K
Q
A
R
A
-
K
L
Q
R
E
L
FF
P
E
C
-----------------
Q
Y
W
G
S
--
E
L
Q
L
P
T
L
D
--
F
E
D
--
V
L
R
Y
---
D
E
H
A
Y
K
W
L
S
T
L
K
K
V
---
G
I
V
----
R
L
T
G
A
S
D
K
P
G
E
V
S
K
L
G
K
R
M
-
G
F
-----------------------
L
--
Y
L
T
F
-----
Y
G
H
T
W
Q
V
Q
D
K
I
D
--
A
N
N
V
A
Y
--------
T
----
T
G
K
L
S
F
H
T
D
Y
P
A
L
-----
H
H
P
-
P
G
V
Q
L
L
H
C
I
K
Q
-----------------------
T
V
T
G
---
G
D
S
E
I
V
D
G
F
---
N
V
---------------
C
------
Q
K
L
K
K
N
N
P
Q
A
F
Q
----
I
L
S
S
T
F
V
D
F
T
D
-----------------------
I
G
---
V
D
Y
C
D
F
S
---
V
Q
S
K
H
K
I
I
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
51.09
23%
-36
- C7 -
4C8R
5
BODG_HUMAN
A:
[96-280]
--------------------------------------------------------------------------
C
F
S
K
Q
A
R
A
-
K
L
Q
R
E
L
FF
P
E
C
-----------------
Q
Y
W
G
S
--
E
L
Q
L
P
T
L
D
--
F
E
D
--
V
L
R
Y
---
D
E
H
A
Y
K
W
L
S
T
L
K
K
V
---
G
I
V
----
R
L
T
G
A
S
D
K
P
G
E
V
S
K
L
G
K
R
M
-
G
F
-----------------------
L
--
Y
L
T
F
-----
Y
G
H
T
W
Q
V
Q
D
K
I
D
--
A
N
N
V
A
Y
--------
T
----
T
G
K
L
S
F
H
T
D
Y
P
A
L
-----
H
H
P
-
P
G
V
Q
L
L
H
C
I
K
Q
-----------------------
T
V
T
G
---
G
D
S
E
I
V
D
G
F
---
N
V
---------------
C
------
Q
K
L
K
K
N
N
P
Q
A
F
Q
----
I
L
S
S
T
F
V
D
F
T
D
-----------------------
I
G
---
V
D
Y
C
D
F
S
---
V
Q
S
K
H
K
I
I
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
50.62
23%
-23
- C7 -
4BHF
4
BODG_HUMAN
A:
[95-279]
--------------------------------------------------------------------------
C
F
S
K
Q
A
R
A
-
K
L
Q
R
E
L
FF
P
E
C
-----------------
Q
Y
W
G
S
--
E
L
Q
L
P
T
L
D
--
F
E
D
--
V
L
R
Y
---
D
E
H
A
Y
K
W
L
S
T
L
K
K
V
---
G
I
V
----
R
L
T
G
A
S
D
K
P
G
E
V
S
K
L
G
K
R
M
-
G
F
-----------------------
L
--
Y
L
T
F
-----
Y
G
H
T
W
Q
V
Q
D
K
I
D
--
A
N
N
V
A
Y
--------
T
----
T
G
K
L
S
F
H
T
D
Y
P
A
L
-----
H
H
P
-
P
G
V
Q
L
L
H
C
I
K
Q
-----------------------
T
V
T
G
---
G
D
S
E
I
V
D
G
F
---
N
V
---------------
C
------
Q
K
L
K
K
N
N
P
Q
A
F
Q
----
I
L
S
S
T
F
V
D
F
T
D
-----------------------
I
G
---
V
D
Y
C
D
F
S
---
V
Q
S
K
H
K
I
I
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
50.57
23%
-29
- C7 -
3O2G
8
BODG_HUMAN
A:
[96-280]
--------------------------------------------------------------------------
C
F
S
K
Q
A
R
A
-
K
L
Q
R
E
L
FF
P
E
C
-----------------
Q
Y
W
G
S
--
E
L
Q
L
P
T
L
D
--
F
E
D
--
V
L
R
Y
---
D
E
H
A
Y
K
W
L
S
T
L
K
K
V
---
G
I
V
----
R
L
T
G
A
S
D
K
P
G
E
V
S
K
L
G
K
R
M
-
G
F
-----------------------
L
--
Y
L
T
F
-----
Y
G
H
T
W
Q
V
Q
D
K
I
D
--
A
N
N
V
A
Y
--------
T
----
T
G
K
L
S
F
H
T
D
Y
P
A
L
-----
H
H
P
-
P
G
V
Q
L
L
H
C
I
K
Q
-----------------------
T
V
T
G
---
G
D
S
E
I
V
D
G
F
---
N
V
---------------
C
------
Q
K
L
K
K
N
N
P
Q
A
F
Q
----
I
L
S
S
T
F
V
D
F
T
D
-----------------------
I
G
---
V
D
Y
C
D
F
S
---
V
Q
S
K
H
K
I
I
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
50.04
23%
-19
- C7 -
4BHI
3
BODG_HUMAN
A:
[95-279]
--------------------------------------------------------------------------
C
F
S
K
Q
A
R
A
-
K
L
Q
R
E
L
FF
P
E
C
-----------------
Q
Y
W
G
S
--
E
L
Q
L
P
T
L
D
--
F
E
D
--
V
L
R
Y
---
D
E
H
A
Y
K
W
L
S
T
L
K
K
V
---
G
I
V
----
R
L
T
G
A
S
D
K
P
G
E
V
S
K
L
G
K
R
M
-
G
F
-----------------------
L
--
Y
L
T
F
-----
Y
G
H
T
W
Q
V
Q
D
K
I
D
--
A
N
N
V
A
Y
--------
T
----
T
G
K
L
S
F
H
T
D
Y
P
A
L
-----
H
H
P
-
P
G
V
Q
L
L
H
C
I
K
Q
-----------------------
T
V
T
G
---
G
D
S
E
I
V
D
G
F
---
N
V
---------------
C
------
Q
K
L
K
K
N
N
P
Q
A
F
Q
----
I
L
S
S
T
F
V
D
F
T
D
-----------------------
I
G
---
V
D
Y
C
D
F
S
---
V
Q
S
K
H
K
I
I
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
49.80
23%
-25
- C7 -
4BG1
4
BODG_HUMAN
A:
[95-279]
--------------------------------------------------------------------------
C
F
S
K
Q
A
R
A
-
K
L
Q
R
E
L
F
F
P
E
C
-----------------
Q
Y
W
G
S
--
E
L
Q
L
P
T
L
D
--
F
E
D
--
V
L
R
Y
---
D
E
H
A
Y
K
W
L
S
T
L
K
K
V
---
G
I
V
----
R
L
T
G
A
S
D
K
P
G
E
V
S
K
L
G
K
R
M
-
G
F
-----------------------
L
--
Y
L
T
F
-----
Y
G
H
T
W
Q
V
Q
D
K
I
D
--
A
N
N
V
A
Y
--------
T
----
T
G
K
L
S
F
H
T
D
Y
P
A
L
-----
H
H
P
-
P
G
V
Q
L
L
H
C
I
K
Q
-----------------------
T
V
T
G
---
G
D
S
E
I
V
D
G
F
---
N
V
---------------
C
------
Q
K
L
K
K
N
N
P
Q
A
F
Q
----
I
L
S
S
T
F
V
D
F
T
D
-----------------------
I
G
---
V
D
Y
C
D
F
S
---
V
Q
S
K
H
K
I
I
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
49.68
23%
-22
- C7 -
4BGK
3
BODG_HUMAN
A:
[95-279]
--------------------------------------------------------------------------
C
F
S
K
Q
A
R
A
-
K
L
Q
R
E
L
F
F
P
E
C
-----------------
Q
Y
W
G
S
--
E
L
Q
L
P
T
L
D
--
F
E
D
--
V
L
R
Y
---
D
E
H
A
Y
K
W
L
S
T
L
K
K
V
---
G
I
V
----
R
L
T
G
A
S
D
K
P
G
E
V
S
K
L
G
K
R
M
-
G
F
-----------------------
L
--
Y
L
T
F
-----
Y
G
H
T
W
Q
V
Q
D
K
I
D
--
A
N
N
V
A
Y
--------
T
----
T
G
K
L
S
F
H
T
D
Y
P
A
L
-----
H
H
P
-
P
G
V
Q
L
L
H
C
I
K
Q
-----------------------
T
V
T
G
---
G
D
S
E
I
V
D
G
F
---
N
V
---------------
C
------
Q
K
L
K
K
N
N
P
Q
A
F
Q
----
I
L
S
S
T
F
V
D
F
T
D
-----------------------
I
G
---
V
D
Y
C
D
F
S
---
V
Q
S
K
H
K
I
I
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
49.65
23%
-28
- C7 -
3MS5
12
BODG_HUMAN
A:
[96-280]
--------------------------------------------------------------------------
C
F
S
K
Q
A
R
A
-
K
L
Q
R
E
L
FF
P
E
C
-----------------
Q
Y
W
G
S
--
E
L
Q
L
P
T
L
D
--
F
E
D
--
V
L
R
Y
---
D
E
H
A
Y
K
W
L
S
T
L
K
K
V
---
G
I
V
----
R
L
T
G
A
S
D
K
P
G
E
V
S
K
L
G
K
R
M
-
G
F
-----------------------
L
--
Y
L
T
F
-----
Y
G
H
T
W
Q
V
Q
D
K
I
D
--
A
N
N
V
A
Y
--------
T
----
T
G
K
L
S
F
H
T
D
Y
P
A
L
-----
H
H
P
-
P
G
V
Q
L
L
H
C
I
K
Q
-----------------------
T
V
T
G
---
G
D
S
E
I
V
D
G
F
---
N
V
---------------
C
------
Q
K
L
K
K
N
N
P
Q
A
F
Q
----
I
L
S
S
T
F
V
D
F
T
D
-----------------------
I
G
---
V
D
Y
C
D
F
S
---
V
Q
S
K
H
K
I
I
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
49.35
23%
-21
- C7 -
4BHG
4
BODG_HUMAN
A:
[95-279]
--------------------------------------------------------------------------
C
F
S
K
Q
A
R
A
-
K
L
Q
R
E
L
FF
P
E
C
-----------------
Q
Y
W
G
S
--
E
L
Q
L
P
T
L
D
--
F
E
D
--
V
L
R
Y
---
D
E
H
A
Y
K
W
L
S
T
L
K
K
V
---
G
I
V
----
R
L
T
G
A
S
D
K
P
G
E
V
S
K
L
G
K
R
M
-
G
F
-----------------------
L
--
Y
L
T
F
-----
Y
G
H
T
W
Q
V
Q
D
K
I
D
--
A
N
N
V
A
Y
--------
T
----
T
G
K
L
S
F
H
T
D
Y
P
A
L
-----
H
H
P
-
P
G
V
Q
L
L
H
C
I
K
Q
-----------------------
T
V
T
G
---
G
D
S
E
I
V
D
G
F
---
N
V
---------------
C
------
Q
K
L
K
K
N
N
P
Q
A
F
Q
----
I
L
S
S
T
F
V
D
F
T
D
-----------------------
I
G
---
V
D
Y
C
D
F
S
---
V
Q
S
K
H
K
I
I
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
49.21
23%
-30
- C7 -
4CWD
3
BODG_HUMAN
A:
[96-280]
--------------------------------------------------------------------------
C
F
S
K
Q
A
R
A
-
K
L
Q
R
E
L
FF
P
E
C
-----------------
Q
Y
W
G
S
--
E
L
Q
L
P
T
L
D
--
F
E
D
--
V
L
R
Y
---
D
E
H
A
Y
K
W
L
S
T
L
K
K
V
---
G
I
V
----
R
L
T
G
A
S
D
K
P
G
E
V
S
K
L
G
K
R
M
-
G
F
-----------------------
L
--
Y
L
T
F
-----
Y
G
H
T
W
Q
V
Q
D
K
I
D
--
A
N
N
V
A
Y
--------
T
----
T
G
K
L
S
F
H
T
D
Y
P
A
L
-----
H
H
P
-
P
G
V
Q
L
L
H
C
I
K
Q
-----------------------
T
V
T
G
---
G
D
S
E
I
V
D
G
F
---
N
V
---------------
C
------
Q
K
L
K
K
N
N
P
Q
A
F
Q
----
I
L
S
S
T
F
V
D
F
T
D
-----------------------
I
G
---
V
D
Y
C
D
F
S
---
V
Q
S
K
H
K
I
I
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
48.22
23%
-26
- C7 -
4BGM
3
BODG_HUMAN
A:
[95-279]
--------------------------------------------------------------------------
C
F
S
K
Q
A
R
A
-
K
L
Q
R
E
L
FF
P
E
C
-----------------
Q
Y
W
G
S
--
E
L
Q
L
P
T
L
D
--
F
E
D
--
V
L
R
Y
---
D
E
H
A
Y
K
W
L
S
T
L
K
K
V
---
G
I
V
----
R
L
T
G
A
S
D
K
P
G
E
V
S
K
L
G
K
R
M
-
G
F
-----------------------
L
--
Y
L
T
F
-----
Y
G
H
T
W
Q
V
Q
D
K
I
D
--
A
N
N
V
A
Y
--------
T
----
T
G
K
L
S
F
H
T
D
Y
P
A
L
-----
H
H
P
-
P
G
V
Q
L
L
H
C
I
K
Q
-----------------------
T
V
T
G
---
G
D
S
E
I
V
D
G
F
---
N
V
---------------
C
------
Q
K
L
K
K
N
N
P
Q
A
F
Q
----
I
L
S
S
T
F
V
D
F
T
D
-----------------------
I
G
---
V
D
Y
C
D
F
S
---
V
Q
S
K
H
K
I
I
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
44.65
18%
-55
- C5 -
4M1K
2
?
A:
[6-688]
EYDLKR
L
R
N
I
G
I
A
A
H
IDAG
K
T
T
T
T
E
R
I
L
Y
Y
T
G
RIAA
V
T
T
C
F
W
KD
H
R
I
N
I
I
DTPG
H
V
D
F
T
I
E
V
E
R
S
M
R
V
L
D
G
A
I
V
V
F
D
S
S
Q
G
V
E
P
-------
Q
S
E
-----------------
T
V
W
R
Q
A
E
K
Y
K
V
P
R
I
A
--
F
A
N
--
K
M
D
K
TGA
D
L
W
L
V
I
--
R
T
M
Q
E
R
LGA
R
P
V
VM
Q
L
P
I
G
R
E
D
T
F
S
G
I
I
D
V
L
R
M
K
A
Y
T
Y
GNDLGTDIREIPIPEEY
L
D
Q
A
R
E
Y
--
H
E
K
L
V
E
V
A
A
D
F
D
E
N
I
M
L
K
Y
L
E
--
G
E
E
P
T
E
E
E
L
V
A
A
--
I
----
R
K
G
T
I
D
L
K
I
T
P
V
F
L
G
S
AL
K
N
K
-
G
V
Q
L
L
L
D
A
V
V
D
YLPSPLD
I
P
P
I
K
G
T
T
PEG
E
V
V
E
I
H
P
D
P
---
N
G
P
L
A
A
L
A
F
---
K
I
M
A
DPYV
G
R
L
T
F
I
R
V
Y
S
G
T
L
T
S
G
S
Y
V
Y
N
T
T
K
G
R
K
E
R
V
A
R
L
L
R
M
H
A
N
H
R
E
E
V
EELKAG
D
L
G
A
V
V
GLKETITG
D
T
L
V
---
G
E
D
A
P
R
V
-
I
L
E
S
I
E
V
P
E
P
V
I
D
V
A
I
E
P
K
T
K
A
D
Q
E
--
K
L
S
Q
A
L
A
R
L
A
E
E
D
P
T
---
F
R
V
S
T
HPET
G
Q
T
I
I
S
G
M
G
E
L
H
L
E
I
I
V
D
R
L
K
R
EFKVDANVGKPQVA
Y
R
---
E
T
I
T
K
P
V
D
V
E
G
K
F
I
R
L
T
G
G
R
G
Q
Y
G
H
V
K
I
K
V
E
P
L
P
R
--------
G
S
G
F
E
F
V
N
AIVGGVIP
K
E
Y
I
P
A
V
Q
K
G
I
E
E
A
M
Q
S
G
P
L
I
-
G
--
F
P
V
V
D
I
K
V
T
L
Y
D
G
-
S
Y
H
EVD
S
S
E
M
A
F
K
I
A
-
G
S
--
M
A
I
K
E
A
V
Q
K
G
D
P
V
I
L
E
P
I
M
R
V
E
V
T
T
P
---------
E
E
Y
M
G
D
V
I
G
D
L
N
A
R
R
G
Q
I
L
G
M
E
P
R
GN
A
Q
V
I
R
A
F
V
P
L
A
--------
E
M
F
G
Y
A
T
D
L
R
S
K
T
Q
GR
G
S
F
V
M
F
F
D
H
Y
Q
E
V
P
K
Q
V
Q
E
K
LI--------
5
PsiBlast_PDB
43.87
23%
-31
- C7 -
3N6W
3
BODG_HUMAN
A:
[111-304]
--------------------------------------------------------------------------
C
F
S
K
Q
A
R
A
-
K
L
Q
R
E
L
FF
P
E
C
-----------------
Q
Y
W
G
S
--
E
L
Q
L
P
T
L
D
--
F
E
D
--
V
L
R
Y
---
D
E
H
A
Y
K
W
L
S
T
L
K
K
V
---
G
I
V
----
R
L
T
G
A
S
D
K
P
G
E
V
S
K
L
G
K
R
M
-
G
F
-----------------------
L
--
Y
L
T
F
-----
Y
G
H
T
W
Q
V
Q
D
--------------------------
K
L
S
F
H
T
D
Y
P
A
L
-----
H
H
P
-
P
G
V
Q
L
L
H
C
I
K
Q
-------------------------------
D
S
E
I
V
D
G
F
---
N
V
---------------
C
------
Q
K
L
K
K
N
N
P
Q
A
F
Q
----
I
L
S
S
T
F
V
D
F
T
D
-----------------------
I
G
---
V
D
Y
C
D
F
S
---
V
Q
S
K
H
K
I
I
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
43.46
16%
-62
- C7 -
4B46
1
CETZ1_HALVD
A:
[1-367]
---------------------------------------------------------------
M
K
L
A
M
I
G
F
G
Q
A
G
G
K
V
V
D
K
F
-
V
-------
E
Y
D
-----------------
R
E
R
N
A
G
I
V
R
A
A
V
A
V
N
--
S
A
-----
K
A
---
D
L
L
G
L
K
--
N
I
P
K
D
Q
---
R
V
L
-----
I
G
Q
S
R
V
K
G
H
G
V
G
A
D
N
E
L
G
A
E
I
-----------------------
A
--
E
E
D
I
-----
D
E
V
Q
G
A
I
D
S
I
P
V
--
H
E
V
D
A
F
L
V
V
S
G
L
--
G
----
G
G
T
G
S
G
G
A
P
V
L
A
K
-----
H
L
K
-
R
I
-----------------------------------
Y
---
T
E
P
V
Y
G
L
G
I
L
P
G
S
D
E
G
----
G
I
Y
T
L
N
A
A
R
S
F
Q
----
T
F
V
R
E
V
D
------------------
N
L
-----------------------
L
V
---
F
D
---
N
D
-
A
W
R
K
T
G
E
S
V
Q
G
G
Y
D
E
I
N
E
E
I
V
N
R
F
G
--
V
L
F
G
S
V
V
D
S
S
E
I
I
N
T
---
L
A
G
G
----------
G
V
S
T
V
G
Y
A
S
E
G
V
T
-------------------
A
---
H
T
T
----
N
R
I
T
S
L
V
R
K
A
A
L
G
R
L
T
L
P
C
E
I
E
G
A
E
R
A
L
L
V
L
A
----
G
P
P
E
H
L
N
---------
R
K
G
I
E
R
G
R
K
W
I
E
E
---
Q
T
G
S
M
---------------------------------------
E
V
R
G
G
D
Y
P
I
P
G
-------------------------------------------------------------------------
A
E
K
V
A
G
--------
V
I
L
L
S
G
V
T
--
N
V
P
R
I
K
E
L
Q
Q
V
A
I
E
A
Q
D
17
PsiBlast_PDB
40.99
24%
-80
- C7 -
3DZD
1
?
A:
[19-151]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
E
E
E
G
Y
H
P
--
D
T
A
K
T
L
R
E
A
E
K
K
--
I
----
K
E
L
F
F
P
V
I
V
L
D
V
W
-----
M
P
D
G
D
G
V
N
F
I
D
F
I
K
E
-----------------------
N
S
P
D
---
S
V
V
I
V
I
T
G
-------------
H
G
S
V
D
T
A
----------
V
K
A
I
K
K
G
A
Y
E
----
F
L
E
K
P
F
S
V
E
R
F
-----------------------
L
L
---
T
I
K
H
A
F
E
-
E
Y
S
K
K
A
P
P
-----
Q
E
E
I
E
F
V
G
E
H
P
K
I
L
E
I
K
R
L
I
P
K
I
A
K
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
40.24
9%
-113
- C7 -
2EBF
-
X:
[361-466]
----------------------------------------------------------------------------------------------------------------------------------------------
E
R
I
E
--
K
C
M
N
T
Y
---
R
G
V
----
A
F
Q
N
-
S
S
K
S
------
I
D
F
F
L
N
N
-----------------------
L
TT
F
I
D
N
-----
G
L
T
E
I
A
I
S
D
L
P
Y
DI
V
Q
Q
E
I
S
Q
F
L
Q
G
S
--
N
EWKT
L
D
A
M
L
F
N
L
D
K
G
-
D
-----
I
N
G
-
A
F
R
K
L
L
Q
S
A
K
D
-------------------------------
N
N
I
K
F
R
A
I
---
G
H
S
D
----
N
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
38.70
8%
-73
- C1 -
2OCA
-
UVSW_BPT4
A:
[1-503]
--------------------------------------MD
I
K
V
H
F
HDFS
H
V
R
I
D
C
E
E
S
T
F
H
E
L
R
D
F
F
S
F
E
A
D
G
Y
R
F
N
P
R
F
R
Y
-
G
-------
N
W
D
GRIRLLDYNRLLPFGLV
G
Q
I
K
K
F
C
D
N
F
G
Y
K
A
W
--
I
D
P
--
Q
I
N
E
---
K
E
E
L
S
R
--
K
D
F
D
E
W
---
L
S
K
----
L
E
I
Y
S
G
N
K
R
I
E
P
H
W
Y
Q
K
D
A
V
F
E
-----------------------
G
--
L
V
N
------
R
R
R
I
L
N
L
P
T
S
A
G
--
R
S
L
I
Q
A
L
L
A
R
Y
Y
--
L
----
E
N
Y
--
E
G
K
I
L
I
I
V
-----
P
T
T
-
A
L
T
T
Q
M
A
D
D
F
V
-----------------------
D
Y
R
L
---
F
S
H
A
M
I
K
K
I
---
G
G
G
A
----
S
K
D
D
K
Y
K
N
D
A
------
P
V
V
V
G
T
W
Q
T
V
V
K
----
Q
P
K
E
W
F
S
Q
F
G
M
-----------------------
M
M
---
N
D
E
--
C
H
-
L
A
T
G
K
S
I
S
S
I
I
S
G
L
N
N
C
M
F
K
F
G
L
S
G
--
S
L
R
D
G
K
A
N
I
M
Q
Y
V
G
M
F
G
E
I
F
K
P
V
-----
T
T
S
E
L
K
I
N
S
I
F
L
R
Y
P
D
E
F
T
T
K
--------------
L
K
GKT
Y
Q
E
----
E
I
K
I
I
T
G
L
S
K
R
N
K
W
I
A
K
L
A
I
K
L
A
Q
K
D
E
N
A
F
V
M
F
K
H
V
S
H
G
K
A
I
F
---------
D
L
I
K
N
E
Y
D
K
V
Y
Y
V
---
S
G
E
V
D
-
T
E
T
R
N
I
M
K
T
L
A
E
N
G
K
G
I
I
I
V
---
A
S
Y
G
V
F
S
T
G
-
I
S
V-
K
N
L
H
H
V
V
L
A
H
G
V
K
S
K
I
I
V
L
Q
T
-
I
G
R
V
L
R
K
HGSKTI
A
T
V
W
D
L
I
D
D
A
G
V
K
--
P
K
S
A
N
T
K
K
K
----
Y
V
H
L
N
Y
L
L
K
--------
H
G
I
D
R
I
Q
R
Y
A
D
--------
E
K
F
N
Y
V
M
K
--
T
V
N
L
L
------------