@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu02460: (2016-06-04 )
MSRIRKAPAGILGFPVAPFNTQGKLEEEALFQNIEFLLNEGLEAIFIACGSGEFQSLSQKEYEQMVEVAVSAAGGKVPVYTGVGGNLSTALDWAQLSEKKGADGYLILPPYLVHGEQEGLYQYAKTIIESTDLNAILYQRDNAVLSVEQIKRLTECEQLVGVKDGVGNMDLNINLVYTIGDRLGWLNGMPMAEVTMPAYLPIGFHSYSSAISNYIPHISRMFYDALKNGNDELVKELYRHVILPINDIRKQRKGYAVSLIKAGMEIMGLNVRNTARPPVGPVEKDHYQQLEAILKQAADRFPKKAATV
Atome Classification :
(20 SA)
---.........10........-20........30........40........50.........60........70........80..-......90........100.....---..110.......120.......130.......---140.......150..-.-....160.......170.......--180-........190.......200.......210.......220.......230.......240.......-250--.-......260.......270.......280.......290.......300......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---MS
R
I
RKAPAGILGFPVAPF-NTQGK
L
E
E
E
A
L
F
Q
N
I
E
F
L
L
NEGL
E
A
I
F
I
ACG-SG
E
F
Q
S
L
S
Q
K
E
Y
E
Q
M
V
E
V
A
V
SAAGGKV
P
V
Y
TGV-GG
N
L
S
T
A
L
D
W
A
Q
L
S
EKKGADG
Y
L
I---L
P
P
Y
LVHGEQ
E
G
L
Y
Q
Y
A
K
T
I
I
ESTDL
N
A
I
L
Y
Q---RDN
A
V
L
S
V
E
Q
I
K
R
L
T
-
E
-
C
E
Q
L
V
GVKDGVG
N
M
D
L
N
I
N
L
V
Y
T
I--GD--RLGWLNGMPMAEVTM
P
A
Y
L
PI
G
F
H
S
Y
S
S
A
I
S
N
Y
I
P
H
I
S
R
M
F
Y
D
A
LKNG
N
D
E
L
V
K
E
L
Y
R
H
V
I
L
P
I
N
D
I
R
-
K
Q
R--K-G
Y
A
V
S
L
I
K
A
G
M
E
I
M
G
L
NVRNTARPPVGPV
E
K
D
H
Y
Q
Q
L
E
A
I
L
K
Q
A
A
D
RFPKKAATV
25
PsiBlast_CBE
90.08
37%
-137
- C7 -
5HWM
3
?
C:
[12-296]
-----------
S
G
L
L
S
F
P
V
T
H
F
-
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
-
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
G
-
E
T
A
I
V
S
G
C
-
G
Y
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
---
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
-
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
--
G
D
--
R
L
M
Y
L
G
G
M
P
T
A
E
L
F
A
E
A
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
V
D
F
F
Y
P
F
M
A
I
R
-
N
R
A
--
K
-
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
-
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
--------------
31
PsiBlast_CBE
89.82
37%
-139
- C7 -
4UR8
3
KDGD_AGRFC
C:
[12-296]
-----------
S
G
L
L
S
F
P
V
T
H
F
-
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
-
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
G
-
E
T
A
I
V
S
G
C
-
G
Y
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
---
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
-
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
--
G
D
--
R
L
M
Y
L
G
G
M
P
T
A
E
L
F
A
E
A
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
V
D
F
F
Y
P
F
M
A
I
R
-
N
R
A
--
K
-
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
-
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
--------------
4
PsiBlast_PDB
89.54
37%
-135
- C7 -
5HWN
8
?
A:
[12-296]
-----------
S
G
L
L
S
F
P
V
T
H
F
-
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
-
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
G
-
E
T
A
I
V
S
G
C
-
G
Y
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
---
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
-
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
--
G
D
--
R
L
M
Y
L
G
G
M
P
T
A
E
L
F
A
E
A
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
V
D
F
F
Y
P
F
M
A
I
R
-
N
R
A
--
K
-
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
-
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
--------------
29
PsiBlast_CBE
89.46
37%
-135
- C7 -
5HWJ
4
?
B:
[12-296]
-----------
S
G
L
L
S
F
P
V
T
H
F
-
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
-
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
G
-
E
T
A
I
V
S
G
C
-
G
Y
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
---
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
-
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
--
G
D
--
R
L
M
Y
L
G
G
M
P
T
A
E
L
F
A
E
A
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
V
D
F
F
Y
P
F
M
A
I
R
-
N
R
A
--
K
-
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
-
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
--------------
2
PsiBlast_PDB
89.36
37%
-135
- C7 -
5HWJ
4
?
A:
[12-296]
-----------
S
G
L
L
S
F
P
V
T
H
F
-
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
-
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
G
-
E
T
A
I
V
S
G
C
-
G
Y
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
---
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
-
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
--
G
D
--
R
L
M
Y
L
G
G
M
P
T
A
E
L
F
A
E
A
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
V
D
F
F
Y
P
F
M
A
I
R
-
N
R
A
--
K
-
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
-
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
--------------
26
PsiBlast_CBE
89.21
37%
-133
- C7 -
5HWM
1
?
B:
[12-296]
-----------
S
G
L
L
S
F
P
V
T
H
F
-
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
-
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
G
-
E
T
A
I
V
S
G
C
-
G
Y
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
---
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
-
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
--
G
D
--
R
L
M
Y
L
G
G
M
P
T
A
E
L
F
A
E
A
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
V
D
F
F
Y
P
F
M
A
I
R
-
N
R
A
--
K
-
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
-
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
--------------
28
PsiBlast_CBE
89.17
37%
-134
- C7 -
5HWJ
3
?
C:
[12-296]
-----------
S
G
L
L
S
F
P
V
T
H
F
-
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
-
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
G
-
E
T
A
I
V
S
G
C
-
G
Y
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
---
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
-
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
--
G
D
--
R
L
M
Y
L
G
G
M
P
T
A
E
L
F
A
E
A
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
V
D
F
F
Y
P
F
M
A
I
R
-
N
R
A
--
K
-
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
-
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
--------------
3
PsiBlast_PDB
89.17
37%
-135
- C7 -
5HWM
1
?
A:
[12-296]
-----------
S
G
L
L
S
F
P
V
T
H
F
-
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
-
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
G
-
E
T
A
I
V
S
G
C
-
G
Y
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
---
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
-
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
--
G
D
--
R
L
M
Y
L
G
G
M
P
T
A
E
L
F
A
E
A
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
V
D
F
F
Y
P
F
M
A
I
R
-
N
R
A
--
K
-
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
-
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
--------------
32
PsiBlast_CBE
88.77
37%
-133
- C7 -
4UR8
1
KDGD_AGRFC
B:
[12-296]
-----------
S
G
L
L
S
F
P
V
T
H
F
-
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
-
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
G
-
E
T
A
I
V
S
G
C
-
G
Y
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
---
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
-
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
--
G
D
--
R
L
M
Y
L
G
G
M
P
T
A
E
L
F
A
E
A
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
V
D
F
F
Y
P
F
M
A
I
R
-
N
R
A
--
K
-
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
-
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
--------------
22
PsiBlast_CBE
88.60
37%
-134
- C7 -
5HWN
5
?
C:
[12-296]
-----------
S
G
L
L
S
F
P
V
T
H
F
-
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
-
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
G
-
E
T
A
I
V
S
G
C
-
G
Y
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
---
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
-
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
--
G
D
--
R
L
M
Y
L
G
G
M
P
T
A
E
L
F
A
E
A
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
V
D
F
F
Y
P
F
M
A
I
R
-
N
R
A
--
K
-
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
-
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
--------------
21
PsiBlast_CBE
88.48
37%
-132
- C7 -
5HWN
7
?
D:
[12-296]
-----------
S
G
L
L
S
F
P
V
T
H
F
-
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
-
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
G
-
E
T
A
I
V
S
G
C
-
G
Y
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
---
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
-
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
--
G
D
--
R
L
M
Y
L
G
G
M
P
T
A
E
L
F
A
E
A
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
V
D
F
F
Y
P
F
M
A
I
R
-
N
R
A
--
K
-
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
-
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
--------------
1
PsiBlast_PDB
88.47
37%
-134
- C7 -
4UR8
1
KDGD_AGRFC
A:
[12-296]
-----------
S
G
L
L
S
F
P
V
T
H
F
-
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
-
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
G
-
E
T
A
I
V
S
G
C
-
G
Y
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
---
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
-
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
--
G
D
--
R
L
M
Y
L
G
G
M
P
T
A
E
L
F
A
E
A
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
V
D
F
F
Y
P
F
M
A
I
R
-
N
R
A
--
K
-
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
-
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
--------------
23
PsiBlast_CBE
87.84
37%
-133
- C7 -
5HWN
5
?
B:
[12-296]
-----------
S
G
L
L
S
F
P
V
T
H
F
-
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
-
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
G
-
E
T
A
I
V
S
G
C
-
G
Y
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
---
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
-
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
--
G
D
--
R
L
M
Y
L
G
G
M
P
T
A
E
L
F
A
E
A
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
V
D
F
F
Y
P
F
M
A
I
R
-
N
R
A
--
K
-
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
-
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
--------------
27
PsiBlast_CBE
87.83
37%
-132
- C7 -
5HWJ
3
?
D:
[12-296]
-----------
S
G
L
L
S
F
P
V
T
H
F
-
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
-
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
G
-
E
T
A
I
V
S
G
C
-
G
Y
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
---
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
-
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
--
G
D
--
R
L
M
Y
L
G
G
M
P
T
A
E
L
F
A
E
A
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
V
D
F
F
Y
P
F
M
A
I
R
-
N
R
A
--
K
-
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
-
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
--------------
24
PsiBlast_CBE
87.48
37%
-132
- C7 -
5HWM
3
?
D:
[12-296]
-----------
S
G
L
L
S
F
P
V
T
H
F
-
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
-
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
G
-
E
T
A
I
V
S
G
C
-
G
Y
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
---
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
-
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
--
G
D
--
R
L
M
Y
L
G
G
M
P
T
A
E
L
F
A
E
A
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
V
D
F
F
Y
P
F
M
A
I
R
-
N
R
A
--
K
-
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
-
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
--------------
30
PsiBlast_CBE
86.81
37%
-132
- C7 -
4UR8
3
KDGD_AGRFC
D:
[12-296]
-----------
S
G
L
L
S
F
P
V
T
H
F
-
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
-
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
G
-
E
T
A
I
V
S
G
C
-
G
Y
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
---
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
-
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
--
G
D
--
R
L
M
Y
L
G
G
M
P
T
A
E
L
F
A
E
A
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
V
D
F
F
Y
P
F
M
A
I
R
-
N
R
A
--
K
-
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
-
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
--------------
53
Fugue
86.52
36%
-126
- C7 -
5HWN
8
?
A:
[1-303]
MD
P
E
Q
I
K
T
A
L
G
S
G
L
L
S
F
P
V
T
H
F
-
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
-
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
G
-
E
T
A
I
V
S
G
C
-
G
Y
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
---
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
-
D
E
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
--
G
D
--
R
L
M
Y
L
G
G
M
P
T
A
E
L
F
A
E
A
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
V
D
F
F
Y
P
F
M
A
I
R
-
N
R
A
--
K
-
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
G
P
V
-
R
A
P
L
----
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
G
T
H
K
R
K
A
---
81
HHSearch
74.76
25%
-113
- C7 -
2EHH
1
DAPA_AQUAE
A:
[1-292]
---------
M
F
Q
G
S
I
V
A
L
I
T
P
F
-
K
E
-
G
E
V
D
Y
E
A
L
G
N
L
I
E
F
H
V
D
N
G
T
D
A
I
L
V
C
G
T
-
T
G
E
S
P
T
L
T
F
E
E
H
E
K
V
I
E
F
A
V
K
R
A
A
G
R
I
K
V
I
A
G
T
G
G
N
A
T
H
E
A
V
H
L
T
A
H
A
K
E
V
G
A
D
G
A
L
V
---
V
V
P
Y
Y
N
K
P
T
Q
R
G
L
Y
E
H
F
K
T
V
A
Q
E
V
D
I
P
I
I
I
Y
N
I
PS
R
T
C
V
E
I
S
V
D
T
M
F
K
L
A
S
E
-
C
E
N
I
V
A
S
K
E
S
T
P
N
M
D
R
I
S
E
I
V
K
R
L
--
G
E
--
S
F
S
V
L
S
G
D
---
D
S
L
T
L
P
M
M
A
L
G
A
K
G
V
I
S
V
A
N
N
V
M
P
R
E
V
K
E
L
I
R
A
A
L
E
G
D
F
R
R
A
R
E
I
H
Y
Y
L
-
H
D
L
F
K
V
L
-
F
I
-----
E
T
N
P
I
P
V
K
T
A
C
W
M
L
G
M
C
E
K
E
-
F
R
L
P
L
T
E
M
S
P
E
N
E
N
K
L
R
E
V
L
K
K
Y
N
L
P
L
-------
9
PsiBlast_PDB
74.74
27%
-118
- C7 -
3E96
-
?
A:
[10-297]
--------
K
A
L
E
T
I
S
G
I
P
I
T
P
F
R
K
S
D
G
S
I
D
W
H
H
Y
K
E
T
V
D
R
I
V
D
N
G
I
D
V
I
-
V
P
C
G
N
T
S
E
F
Y
A
L
S
L
E
E
A
K
E
E
V
R
R
T
V
E
Y
V
H
G
R
A
L
V
V
A
G
I
-
G
Y
A
T
S
T
A
I
E
L
G
N
A
A
K
A
A
G
A
D
A
V
M
I
H
MP
I
H
P
Y
V
T
A
G
---
G
V
Y
A
Y
F
R
D
I
I
E
A
L
D
F
P
S
L
V
Y
F
---
K
D
P
E
I
-
S
D
R
V
L
V
D
L
A
-
P
-
L
Q
N
L
V
G
V
K
Y
A
I
N
D
L
P
R
F
A
K
V
V
R
S
I
--
P
E
EH
Q
I
A
W
I
C
G
--
T
A
E
K
W
A
P
F
F
W
H
A
G
A
K
G
F
T
S
G
L
V
N
L
L
P
Q
K
A
V
E
M
L
E
A
L
R
N
N
D
N
D
A
V
W
R
I
W
E
D
I
V
-
P
F
E
D
L
R
G
K
Y
N
--
Q
-
G
N
N
V
V
V
I
K
E
A
M
E
M
L
R
Q
N
A
G
V
T
-
R
A
P
V
N
E
L
S
N
E
D
K
Q
L
V
T
E
L
L
--------------
64
HHSearch
73.94
24%
-122
- C7 -
4XKY
1
?
A:
[3-299]
--------
I
P
L
S
G
I
I
P
P
L
V
T
P
L
-
L
D
D
D
V
L
D
V
E
G
L
Q
R
L
I
E
H
L
I
A
G
G
V
H
A
L
F
V
L
G
T
-
T
G
E
S
Q
S
L
S
Y
K
L
R
M
E
M
I
K
N
T
C
R
I
A
K
G
R
L
P
V
L
V
C
I
S
D
T
S
I
V
E
S
V
N
L
A
C
L
A
A
D
H
G
A
D
A
V
V
S
---
A
P
P
Y
Y
F
A
T
G
Q
P
E
L
I
E
F
Y
E
H
L
L
P
Q
L
P
L
P
L
F
L
Y
N
MPT
H
T
K
V
N
F
A
P
A
T
I
Q
R
I
A
-
E
-
N
P
G
V
I
G
F
K
D
S
S
A
N
T
V
Y
F
Q
S
V
M
Y
A
M
KD
N
P
--
D
F
S
M
L
V
G
P
---
E
E
I
M
A
E
S
V
L
L
G
A
H
G
G
V
N
G
G
A
N
M
F
P
E
L
Y
V
S
L
Y
N
A
A
K
N
A
D
M
E
E
V
R
R
L
Q
E
K
V
-
M
Q
I
S
A
T
I
-
Y
T
V
GQ
H
G
S
S
Y
L
K
G
L
K
C
A
L
S
L
L
G
I
C
S
D
Y
-
V
A
A
P
F
H
K
F
E
Q
R
E
R
G
K
I
W
K
A
L
Q
N
L
G
----------