@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu02560: (2016-06-04 )
MTVLWVAAVIALACLNVIQFIMKKKRDGNLAYTADQLSYMLSRDSAGQILLPTDDHALKDLLVNINLIVENRQQISAQFAKTEQSMKRMLTNMSHDLKTPLTVILGYIEAIQSDPNMPDEERERLLGKLRQKTNELIQMINSFFDLAKLESEDKEIPITKVHMNDICKRNILHYYDAVQSKGFQAAIDIPDTPVYAQANEEALDRILQNLLSNAIQYGAAGKLIGLTLSYDERNIAITVWDRGKGISETDQQRVFERLYTLEESRNKAFQGSGLGLTITKRLTEKMGGIISVQSKPYERTAFTITLKRMTY
Atome Classification :
(20 SA)
------------------------------------------.........10........20........30.-------.......40........50------.........60........70...-------.....80----------------------.........90........100.......110.....----..-120.......130.......140.......150.......160.......--170......------.180--.-----.......-190........200.......210......---.220-------.---.--------......---230.......240.......250.......260.......270.......280..-.....290.......300.......310--
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------------------------MT
V
L
W
V
A
A
V
I
A
L
A
C
L
N
V
I
Q
F
I
M
KKKRDGN
L
A
Y
-------
T
A
D
Q
L
S
Y
M
LSRDSAG
Q
I
L
-------LPTD
D
H
A
L
K
D
L
L
V
N
I
N
L
I
VE
N
R
Q
Q
-------
I
S
A
Q
F
A
-----------------------
K
T
E
Q
S
M
K
R
M
L
T
N
MSHDL
K
T
P
L
T
V
I
L
G
Y
I
E
A
I
QSDPNM----
P
D
-
E
E
R
E
R
L
L
G
K
L
R
Q
K
T
N
E
L
I
Q
M
I
N
S
F
F
D
L
A
K
LESEDKEI
P
I
T
K
V
H
M
N
D
I
C
K
R
--
N
I
L
H
Y
Y
D
A
V
------
Q
SK---G-----
F
Q
A
A
IDI-P-DTP
V
Y
AQA
N
E
E
A
L
D
R
I
L
Q
N
L
L
S
N
A
I
QYG---AAG--------
K
---
L
--------
I
G
L
T
L
S
---YDE
R
N
I
A
I
T
V
WDRGKGIS
E
T
D
Q
Q
R
V
F
E
R
L
Y
T
L
E
E
SRNKAFQGSGLG
L
T
I
T
K
R
L
T
E
-KMG
G
I
I
S
VQSKPY
E
R
T
A
F
T
I
T
L
KRMTY---
38
HHSearch
81.43
26%
-132
- C1 -
2C2A
2
?
A:
[17-249]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
R
M
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
K
A
Y
A
E
T
I
Y
N
S
L
G
E
L---
D
L
-
S
T
L
K
E
F
L
E
V
I
I
D
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
--
A
V
N
A
I
K
E
F
A
------
S
S
H
---
N
-----
V
N
V
L
F
E
S
-
N
V
P
C
P
V
E
A
Y
I
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
---
K
K
D
--------
A
P
D
K
Y
--------
V
K
V
I
L
D
---
E
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
---------
T
G
L
G
L
A
I
T
K
E
I
V
E
-
L
H
G
G
R
I
W
V
E
S
E
V
G
K
G
S
R
F
F
V
W
I
P
K
D
R
----
3
PsiBlast_PDB
78.08
26%
-113
- C1 -
4U7O
1
?
A:
[30-263]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
D
N
D
R
K
Q
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
L
R
S
Y
I
E
A
L
S
D
G
A
W
K
----
D
P
-
E
V
A
P
G
F
L
K
V
T
Q
E
E
T
D
R
M
I
R
M
I
N
E
L
L
S
L
S
R
M
D
S
G
T
T
R
V
D
M
E
L
V
N
I
N
E
M
F
N
Y
---
V
L
D
R
F
D
M
I
L
KKDDN
P
A
K
---
Y
-----
Y
T
I
K
R
E
F
-
T
-
K
R
D
L
W
V
E
I
D
T
D
K
F
T
Q
V
L
D
N
I
M
N
N
A
I
K
Y
S
---
P
D
G
--------
G
---
V
--------
V
T
C
R
L
L
---
E
T
H
N
Q
V
I
I
S
I
S
D
Q
G
L
G
I
P
R
A
D
L
G
H
V
F
D
R
F
F
R
V
D
K
-----
Q
G
G
T
G
L
G
L
A
I
S
K
E
V
V
Q
-
M
L
G
G
R
I
W
V
D
S
V
E
G
K
G
S
T
F
Y
I
S
L
P
Y
E
-----
35
HHSearch
77.39
25%
-117
- C1 -
4U7O
1
?
A:
[32-263]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
N
D
R
K
Q
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
L
R
S
Y
I
E
A
L
S
D
G
A
W
K
----
D
P
-
E
V
A
P
G
F
L
K
V
T
Q
E
E
T
D
R
M
I
R
M
I
N
E
L
L
S
L
S
R
M
D
S
G
T
T
R
V
D
M
E
L
V
N
I
N
E
M
F
N
Y
--
V
L
D
R
F
D
M
I
L
------
K
K
D
---
D
NPA
K
Y
Y
T
I
K
R
E
F
-
T
-
K
R
D
L
W
V
E
I
D
T
D
K
F
T
Q
V
L
D
N
I
M
N
N
A
I
K
Y
S
---
P
D
G
--------
G
---
V
--------
V
T
C
R
L
L
---
E
T
H
N
Q
V
I
I
S
I
S
D
Q
G
L
G
I
P
R
A
D
L
G
H
V
F
D
R
F
F
R
V
D
K
-----
Q
G
G
T
G
L
G
L
A
I
S
K
E
V
V
Q
-
M
L
G
G
R
I
W
V
D
S
V
E
G
K
G
S
T
F
Y
I
S
L
P
Y
E
-----
9
PsiBlast_PDB
76.89
28%
-127
- C1 -
2C2A
2
?
A:
[23-247]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
K
A
Y
A
E
T
I
Y
N
S
L
G
E
----
L
D
L
S
T
L
K
E
F
L
E
V
I
I
D
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
A
V
N
A
I
K
E
F
A
S
S
------
H
N
V
---
N
-----
V
L
F
E
S
N
V
-
P
--
C
P
V
E
A
Y
I
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
KKD
A
P
D
--------
K
---
Y
--------
V
K
V
I
L
D
---
E
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
---------
T
G
L
G
L
A
I
T
K
E
I
V
E
-
L
H
G
G
R
I
W
V
E
S
E
V
G
K
G
S
R
F
F
V
W
I
P
K
------
2
PsiBlast_PDB
76.88
26%
-127
- C1 -
4U7N
-
?
A:
[386-610]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
S
N
V
S
H
E
L
R
T
P
L
T
S
L
R
S
Y
I
E
A
L
S
D
G
A
W
K
----
D
P
-
E
V
A
P
G
F
L
K
V
T
Q
E
E
T
D
R
M
I
R
M
I
N
E
L
L
S
L
S
R
M
D
S
G
T
T
R
V
D
M
E
L
V
N
I
N
E
M
F
N
Y
---
V
L
D
R
F
D
M
I
L
K
K
DDN------
Y
-----
Y
T
I
K
R
E
F
-
T
-
K
R
D
L
W
V
E
I
D
T
D
K
F
T
Q
V
L
D
N
I
M
N
N
A
I
K
Y
S
---
P
D
G
--------
G
---
V
--------
V
T
C
R
L
L
---
E
T
H
N
Q
V
I
I
S
I
S
D
Q
G
L
G
I
P
R
A
D
L
G
H
V
F
D
R
F
F
R
-----------
T
G
L
G
L
A
I
S
K
E
V
V
Q
-
M
L
G
G
R
I
W
V
D
S
V
E
G
K
G
S
T
F
Y
I
S
L
P
Y
E
-----
4
PsiBlast_PDB
76.21
29%
-113
- C1 -
4JAS
2
?
A:
[23-247]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
A
N
I
S
H
E
L
R
T
P
L
T
V
I
K
G
Y
A
E
M
I
Y
N
S
L
G
E
----
L
D
L
S
T
L
K
E
F
L
E
T
I
I
E
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
A
V
N
A
I
K
E
F
A
S
S
------
H
N
V
---
N
-----
V
L
F
E
S
N
V
-
P
--
C
P
V
E
A
Y
I
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
KKD
A
P
D
--------
K
---
Y
--------
V
K
V
I
L
D
---
E
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
S
S
L
T
Y
E
V
P
G
T
G
L
G
L
A
I
T
K
E
I
V
E
-
L
H
G
G
R
I
W
V
E
S
E
V
G
K
G
S
R
F
F
V
W
I
P
K
------
5
PsiBlast_PDB
75.34
29%
-128
- C1 -
4JAU
1
?
A:
[23-247]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
A
N
I
S
H
E
L
R
T
P
L
T
V
I
K
G
Y
A
E
M
I
Y
N
S
L
G
E
----
L
D
L
S
T
L
K
E
F
L
E
T
I
I
E
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
A
V
N
A
I
K
E
F
A
S
S
------
H
N
V
---
N
-----
V
L
F
E
S
N
V
-
P
--
C
P
V
E
A
Y
I
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
KKD
A
P
D
--------
K
---
Y
--------
V
K
V
I
L
D
---
E
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
S
---------
G
L
G
L
A
I
T
K
E
I
V
E
-
L
H
G
G
R
I
W
V
E
S
E
V
G
K
G
S
R
F
F
V
W
I
P
K
------
8
PsiBlast_PDB
73.27
28%
-118
- C1 -
4JAV
6
?
A:
[23-247]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
K
A
Y
A
E
T
I
Y
N
S
L
G
E
----
L
D
L
S
T
L
K
E
F
L
E
V
I
I
D
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
A
V
N
A
I
K
E
F
A
S
S
------
H
N
V
---
N
-----
V
L
F
E
S
N
V
-
P
--
C
P
V
E
A
Y
I
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
KKD
A
P
D
--------
K
---
Y
--------
V
K
V
I
L
D
---
E
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
S
S
L
T
Y
E
V
P
G
T
G
L
G
L
A
I
T
K
E
I
V
E
-
L
H
G
G
R
I
W
V
E
S
E
V
G
K
G
S
R
F
F
V
W
I
P
K
------
7
PsiBlast_PDB
73.02
28%
-117
- C1 -
3DGE
3
?
A:
[23-247]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
K
A
Y
A
E
T
I
Y
N
S
L
G
E
----
L
D
L
S
T
L
K
E
F
L
E
V
I
I
D
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
A
V
N
A
I
K
E
F
A
S
S
------
H
N
V
---
N
-----
V
L
F
E
S
N
V
-
P
--
C
P
V
E
A
Y
I
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
K
Y
S
KKD
A
P
D
--------
K
---
Y
--------
V
K
V
I
L
D
---
E
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
S
S
L
T
Y
E
V
P
G
T
G
L
G
L
A
I
T
K
E
I
V
E
-
L
H
G
G
R
I
W
V
E
S
E
V
G
K
G
S
R
F
F
V
W
I
P
K
------
32
HHSearch
67.19
20%
-108
- C1 -
4BIX
3
CPXA_ECOLI
A:
[61-296]
-------------------------------------------------------------------------------------------------------------------
A
A
G
A
S
F
N
Q
V
V
T
A
L
E
R
-------------------------------------
M
M
T
S
Q
Q
R
L
L
S
D
I
S
H
E
L
R
T
P
L
T
R
L
Q
L
G
T
A
L
L
R
R
R
S
G
----------
E
S
K
E
L
E
R
I
E
T
E
A
Q
R
L
D
S
M
I
N
D
L
L
V
M
S
R
N
Q
Q
K
N
-
A
L
V
S
E
T
I
K
A
N
Q
L
W
S
E
--
V
L
D
N
A
A
F
E
A
------
E
Q
M
---
G
-----
K
S
L
T
V
N
F
-
P
-
P
G
P
W
P
L
Y
G
N
P
N
A
L
E
S
A
L
E
N
I
V
R
N
A
L
R
Y
S
---
H
T
K
---------------------
I
E
V
G
F
A
---
V
D
K
D
G
I
T
I
T
V
D
D
D
G
P
G
V
S
P
E
D
R
E
Q
I
F
R
P
F
Y
R
T
D
--------
G
T
G
L
G
L
A
I
V
E
T
A
I
Q
-
Q
H
R
G
W
V
K
A
E
D
S
P
L
G
G
L
R
L
V
I
W
L
P
L
Y
K
----
22
Fugue
60.39
19%
-126
- C1 -
1ID0
2
A:
[1-146]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
E
L
H
P
V
A
P
L
L
D
N
--
L
T
S
A
L
N
K
V
Y
------
Q
R
K
---
G
-----
V
N
I
S
L
D
I
-
S
-
P
-
E
I
S
F
V
G
E
Q
N
D
F
V
E
V
M
G
N
V
L
D
N
A
C
K
Y
-----
C
L
--------
E
---
F
--------
V
E
I
S
A
R
---
Q
T
D
E
H
L
Y
I
V
V
E
D
D
G
P
G
I
P
L
S
K
R
E
V
I
F
D
R
G
Q
R
V
D
T
L
R
P
----
G
Q
G
V
G
L
A
V
A
R
E
I
T
E
-
Q
Y
E
G
K
I
V
A
G
E
S
M
L
G
G
A
R
M
E
V
I
F
G
R
Q
H
----
21
Fugue
59.16
24%
-67
- C1 -
4I5S
-
?
A:
[37-432]
N
N
N
Q
V
K
Q
L
N
A
K
V
R
S
L
I
T
G
H
Y
T
D
K
LKVEDNS
D
L
S
E
L
V
N
N
V
N
D
L
S
E
V
F
R
L
T
H
E
N
L
A
Q
E
K
N
R
L
T
S
I
L
S
Y
M
T
D
G
V
L
A
T
D
RSGKIT
V
I
N
D
M
A
Q
K
Q
L
N
V
T
R
E
Q
A
L
ECNILDI
L
D
D
D
S
Y
T
Y
N
D
L
I
T
K
T
P
E
I
V
L
T
R
R
D
EYD
E
F
I
T
L
R
I
R
F
A
L
NRRESGFIS
G
L
I
A
V
L
H
DA
T
E
Q
E
K
E
E
R
E
R
R
L
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
V
K
S
Y
L
E
A
L
-
D
D
G
A
L
----
T
E
-
S
V
A
P
S
F
I
K
V
S
L
D
E
T
N
R
M
M
R
M
I
T
D
L
L
S
L
S
R
S
H
-----
L
D
V
E
L
T
N
F
T
A
F
M
N
Y
--
I
L
D
R
F
D
Q
I
Q
------
S
Q
Q
---
S
-----
T
E
I
I
R
D
Y
-
P
-
D
K
S
V
W
I
E
I
D
T
D
K
M
T
Q
V
I
D
N
I
L
N
N
A
I
K
Y
S
---
P
D
G
--------
G
---
K
--------
V
T
I
T
M
Q
---
T
T
D
T
Q
L
I
L
S
I
S
D
Q
G
L
G
I
P
K
K
D
L
P
L
I
F
D
R
F
Y
R
V
D
K
A
R
-------
G
L
G
L
A
I
A
K
E
I
V
K
-
Q
H
K
G
F
I
W
A
N
S
E
E
G
E
G
S
T
F
T
I
V
L
P
-------
34
HHSearch
58.93
24%
-84
- C1 -
4Q20
-
DIVL_CAUCR
A:
[534-758]
---------------------------------------------------------------------------------------------------------------------------------------------
L
A
-----------------------
E
A
E
R
L
K
R
D
F
V
G
N
V
S
Y
E
L
R
T
P
L
T
T
I
I
G
Y
S
E
L
L
E
R
A
D
-------
S
-
E
R
G
R
N
H
V
A
A
V
R
A
A
A
T
Q
L
A
R
S
I
D
D
V
L
D
M
A
Q
I
D
A
G
E
M
A
L
E
I
E
D
I
R
V
S
D
L
L
L
N
--
A
Q
E
R
A
L
K
D
A
------
Q
L
G
---
G
-----
V
T
L
A
V
E
C
-
E
-
E
D
V
G
L
I
R
G
D
G
K
R
L
A
Q
T
L
D
H
L
V
E
N
A
L
R
Q
T
---
P
P
G
--------
G
---
R
--------
V
T
L
S
A
R
---
R
A
L
G
E
V
R
L
D
V
S
D
T
G
R
G
V
P
F
H
V
Q
A
H
I
F
D
R
F
V
G
R
D
------
R
G
G
P
G
L
G
L
A
L
V
K
A
L
V
E
-
L
H
G
G
W
V
A
L
E
S
E
P
G
N
G
S
T
F
T
C
H
L
P
E
T
Q
----
45
HHSearch
58.37
19%
-102
- C1 -
4GCZ
5
FIXL_BRADU (first)
A:
[151-373]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
M
G
E
M
A
S
A
L
A
H
E
L
N
Q
P
L
A
A
I
S
N
Y
M
K
G
S
R
R
L
L
A
G
SSDP
N
T
-
P
K
V
E
S
A
L
D
R
A
A
E
Q
A
L
R
A
G
Q
I
I
R
R
L
R
D
F
V
A
R
G
E
S
----
E
K
R
V
E
S
L
S
K
L
I
E
E
--
A
G
A
L
G
L
A
G
A
------
R
E
Q
---
N
-----
V
Q
L
R
F
S
L
-
D
-
P
G
A
D
L
V
L
A
D
R
V
Q
I
Q
Q
V
L
V
N
L
F
R
N
A
L
E
A
M
---
A
Q
S
--------
Q
---
R
--------
R
E
L
V
V
T
N
T
P
A
A
D
D
M
I
E
V
E
V
S
D
T
G
S
G
F
Q
D
D
V
I
P
N
L
F
Q
T
F
F
T
T
K
------
D
T
G
M
G
V
G
L
S
I
S
R
S
I
I
E
-
A
H
G
G
R
M
W
A
E
S
N
A
S
G
G
A
T
F
R
F
T
L
P
A
A
D
----
25
Fugue
58.36
15%
-101
- C1 -
1GKZ
8
BCKD_RAT
A:
[38-378]
-------------------------------------------
V
R
L
T
P
T
M
M
L
Y
S
G
R
S
Q
D
-
G
S
H
L
L
K
S
G
R
Y
L
Q
Q
E
-------
L
P
V
R
I
A
H
R
I
K
G
F
R
S
L
P
F
I
-------
I
G
C
N
P
T
I
L
H
V
H
E
L
Y
I
R
A
F
Q
K
L
T
D
F
-------
P
P
I
K
D
Q
-----------------------
A
D
E
A
Q
Y
C
Q
L
V
R
Q
L
L
D
D
H
K
D
V
V
T
L
L
A
E
G
L
R
E
S
R
-
K
H
I
E
----
D
E
-
K
L
V
R
Y
F
L
D
K
T
L
T
S
R
L
G
I
R
M
L
A
T
H
H
L
A
L
H
E
D
K
P
D
F
V
G
I
I
C
T
R
L
S
P
K
K
I
I
E
K
--
W
V
D
F
A
R
R
L
C
------
E
H
K
Y--
G
-----
N
A
P
R
V
R
I
N
G
-
H
V
A
A
R
F
P
F
I
P
M
P
L
D
Y
I
L
P
E
L
L
K
N
A
M
R
A
T
---
M
E
S
--------
H
---
L
DTPY
N
V
P
D
V
V
I
T
I
A
---
N
N
D
V
D
L
I
I
R
I
S
D
R
G
G
G
I
A
H
K
D
L
D
R
V
M
D
Y
H
F
T
-----
T
A
P
M
H
G
F
G
F
G
L
P
T
S
R
A
Y
A
E
-
Y
L
G
G
S
L
Q
L
Q
S
L
Q
G
I
G
T
D
V
Y
L
R
L
R
H
I
D
G
REE
54
HHSearch
58.28
19%
-131
- C1 -
1ID0
2
A:
[5-145]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
V
A
P
L
L
D
N
--
L
T
S
A
L
N
K
V
Y
------
Q
R
K
---
G
-----
V
N
I
S
L
D
I
-
S
-
P
-
E
I
S
F
V
G
E
Q
N
D
F
V
E
V
M
G
N
V
L
D
N
A
C
K
Y
C
---
L
E
F
---------------------
V
E
I
S
A
R
---
Q
T
D
E
H
L
Y
I
V
V
E
D
D
G
P
G
I
P
L
S
K
R
E
V
I
F
D
R
G
Q
R
V
D
T
----
L
R
P
G
Q
G
V
G
L
A
V
A
R
E
I
T
E
-
Q
Y
E
G
K
I
V
A
G
E
S
M
L
G
G
A
R
M
E
V
I
F
G
R
Q
-----
39
HHSearch
58.12
19%
-115
- C1 -
3A0R
1
?
A:
[131-346]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
G
E
M
T
A
R
V
A
H
E
I
R
N
P
I
T
I
I
G
G
F
I
M
R
M
K
K
H
L
D
D
-----
P
-
E
T
L
K
K
Y
I
N
I
I
T
N
E
L
S
R
L
E
T
I
V
K
E
I
L
E
Y
S
K
E
R
----
V
L
E
F
T
E
F
N
L
N
E
L
I
R
E
--
V
Y
V
L
F
E
E
K
I
------
R
K
M
---
N
-----
I
D
F
C
F
E
T
-
D
-
N
E
D
L
R
V
E
A
D
R
T
R
I
K
Q
V
L
I
N
L
V
Q
N
A
I
E
A
T
---
G
E
N
--------
G
---
K
--------
I
K
I
T
S
E
---
D
M
Y
T
K
V
R
V
S
V
W
N
S
G
P
P
I
P
E
E
L
K
E
K
I
F
S
P
F
F
T
T
------------
L
G
L
S
I
C
R
K
I
I
E
D
E
H
G
G
K
I
W
T
E
N
R
-
E
N
G
V
V
F
I
F
E
I
P
K
T
P
----
6
PsiBlast_PDB
58.08
23%
-83
- C1 -
4Q20
-
DIVL_CAUCR
A:
[526-754]
--------------------------------------------------------------------------------------------------------------------
A
L
A
D
R
-----------------
S
A
A
L
A
-----------------------
E
A
E
R
L
K
R
D
F
V
G
N
V
S
Y
E
L
R
T
P
L
T
T
I
I
G
Y
S
E
L
L
E
R
A
D
------
S
E
-
R
G
R
N
H
-
V
A
A
V
R
A
A
A
T
Q
L
A
R
S
I
D
D
V
L
D
M
A
Q
I
D
A
G
E
M
A
L
E
I
E
D
I
R
V
S
D
L
L
L
N
--
A
Q
E
R
A
L
K
D
A
------
Q
L
G
---
G
-----
V
T
L
A
V
E
C
-
E
-
E
D
V
G
L
I
R
G
D
G
K
R
L
A
Q
T
L
D
H
L
V
E
N
A
L
R
Q
T
---
P
P
G
--------
G
---
R
--------
V
T
L
S
A
R
---
R
A
L
G
E
V
R
L
D
V
S
D
T
G
R
G
V
P
F
H
V
Q
A
H
I
F
D
R
F
V
----
G
R
D
R
G
--
G
P
G
L
G
L
A
L
V
K
A
L
V
E
-
L
H
G
G
W
V
A
L
E
S
E
P
G
N
G
S
T
F
T
C
H
L
--------
51
HHSearch
57.10
20%
-127
- C- -
3A0Y
-
?
A:
[608-751]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
N
L
N
E
L
I
R
E
--
V
Y
V
L
F
E
E
K
I
------
R
K
M
---
N
-----
I
D
F
C
F
E
T
-
D
-
N
E
D
L
R
V
E
A
D
R
T
R
I
K
Q
V
L
I
N
L
V
Q
N
A
I
E
A
T
---
G
E
N
--------
G
---
K
--------
I
K
I
T
S
E
---
D
M
Y
T
K
V
R
V
S
V
W
N
S
G
P
P
I
P
E
E
L
K
E
K
I
F
S
P
F
F
T
T
K
--------
G
T
G
L
G
L
S
I
C
R
K
I
I
E
D
E
H
G
G
K
I
W
T
E
N
R
-
E
N
G
V
V
F
I
F
E
I
P
K
T
-----
36
HHSearch
56.71
19%
-119
- C1 -
4E01
4
BCKD_RAT
A:
[148-403]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
Q
Y
C
Q
L
V
R
Q
L
L
D
D
H
K
D
V
V
T
L
L
A
E
G
L
R
E
S
R
K
H
I
E
-----
D
E
-
K
L
V
R
Y
F
L
D
K
T
L
T
S
R
L
G
I
R
M
L
A
T
H
H
L
A
L
H
E
D
K
P
D
F
V
G
I
I
C
T
R
L
S
P
K
K
I
I
E
K
--
W
V
D
F
A
R
R
L
C
------
E
H
K
YG
N
A
-----
P
R
V
R
I
N
G
-
H
--
V
A
A
R
F
P
F
I
P
M
P
L
D
Y
I
L
P
E
L
L
K
N
A
M
R
A
T
---
M
E
S
H
LDTPY
N
V
P
---
D
--------
V
V
I
T
I
A
---
N
N
D
V
D
L
I
I
R
I
S
D
R
G
G
G
I
A
H
K
D
L
D
R
V
M
D
Y
H
F
T
T
A
--------
G
F
G
F
G
L
P
T
S
R
A
Y
A
E
-
Y
L
G
G
S
L
Q
L
Q
S
L
Q
G
I
G
T
D
V
Y
L
R
L
R
H
I
-----