@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu02750: (2016-06-04 )
MITLTDCSRRFQDKKKVVKAVRDVSLTIEKGEVVGILGENGAGKTTMLRMIASLLEPSQGVITVDGFDTVKQPAEVKQRIGVLFGGETGLYDRMTAKENLQYFGRLYGLNRHEIKARIEDLSKRFGMRDYMNRRVGGFSKGMRQKVAIARALIHDPDIILFDEPTTGLDITSSNIFREFIQQLKREQKTILFSSHIMEEVQALCDSVIMIHSGEVIYRGALESLYESERSEDLNYIFMSKLVRGIS
Atome Classification :
(24 SA)
---.........10........20........30........40........50........60.....---..----.70.-----..---.....--80.-.......-90........100-..-....-.110.......120....---...130.......140.......150.......160.......170......-.180..-.-..-.-.190.......200.......210.......220...---....230.......240....---------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---
M
I
T
L
T
D
C
S
R
R
F
Q
D
K
K
K
V
V
K
A
V
R
D
V
S
L
T
I
EKG
E
V
V
G
I
LGENGA
G
K
T
T
M
L
R
M
I
A
S
L
LEPSQ
G
V
I
T
VDG---FD----TVK
Q
-----
P
A
---
E
V
K
Q
R
--
I
G
V
-
L
FGGETG-LYDRM
T
A
K
E
N
L
Q
Y
-
F
G
-
R
L
YG-L
N
R
H
E
I
K
A
R
I
E
D
L
S
K
RFG---
M
R
D
Y
M
N
R
RVG
G
F
S
K
G
M
R
Q
K
V
A
I
A
R
A
LIHDP
D
I
I
L
FDEPTTGLDI
T
S
S
N
I
F
R
E
-
F
I
Q
Q
L
K
-
R
-
E
Q
-
K
-
T
I
L
F
S
S
H
I
M
E
E
V
Q
A
L
C
D
S
V
I
M
IHSG
E
V
I
Y
R
G
A
L
E
S
L
Y
---
E
S
E
RSED
L
N
Y
I
F
M
S
K
L
V
RGIS---------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
85.25
37%
-138
- C1 -
1VPL
2
?
A:
[16-246]
----
V
V
V
K
D
L
R
K
R
I
-
G
K
K
E
I
L
K
G
I
---
S
F
E
I
E
E
G
E
I
F
G
L
I
G
P
N
G
A
G
K
T
T
T
L
R
I
I
S
T
L
I
K
P
S
S
G
I
V
T
V
F
G
---
K
N
----
V
V
E
E
-----
P
H
---
E
V
R
K
L
--
I
S
Y
-
L
-
P
E
E
A
G
-
A
Y
R
N
M
Q
G
I
E
Y
L
R
F
-
V
A
-
G
F
Y
A
-
S
S
S
S
E
I
E
E
M
V
E
R
A
T
E
I
A
G
---
L
G
E
K
I
K
D
R
V
S
T
Y
S
K
G
M
V
R
K
L
L
I
A
R
A
L
M
V
N
P
R
L
A
I
L
D
E
P
T
S
G
L
D
V
L
N
A
R
E
V
R
K
-
I
L
K
Q
A
S
-
Q
-
E
G
-
L
-
T
I
L
V
S
S
H
N
M
L
E
V
E
F
L
C
D
R
I
A
L
I
H
N
G
T
I
V
E
T
G
T
V
E
E
L
K
---
E
R
Y
K
A
Q
N
I
E
E
V
F
------------------------------------------------------------------------------------------------------------------
52
HHSearch
77.83
36%
-133
- C1 -
4YER
4
?
A:
[5-257]
---
I
I
V
V
E
N
L
V
K
K
F
G
----
D
F
E
A
V
K
G
V
S
F
S
V
K
K
G
E
I
F
A
F
L
G
P
N
G
A
G
K
T
T
T
I
H
M
L
T
T
L
L
K
P
T
S
G
K
A
W
V
A
G
---
H
D
----
V
L
K
E
-----
P
R
---
E
V
R
R
K
--
I
G
I
-
V
F
Q
D
Q
-
S
-
L
D
R
E
L
T
A
Y
E
N
M
Y
I
-
H
G
-
K
I
Y
G
-
Y
G
G
E
K
L
K
K
R
I
L
E
L
L
E
F
V
E
---
L
L
E
F
K
D
K
P
V
K
T
F
S
G
G
M
A
R
R
L
E
I
A
R
S
L
I
H
E
P
E
V
L
F
L
D
E
P
T
I
G
L
D
P
H
T
R
A
H
M
W
E
-
Y
I
S
K
M
K
-
K
E
H
N
-
M
-
T
I
F
L
T
T
H
Y
M
D
E
A
E
Q
L
A
D
R
V
A
I
I
D
H
G
K
I
I
A
L
G
T
P
T
E
L
K
---
R
M
V
G
--------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
75.44
30%
-132
- C1 -
4YMU
2
?
J:
[1-240]
---
M
I
F
V
N
D
V
Y
K
N
F
G
S
----
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
---
V
K
----
I
N
N
G
-----
K
V
NIN
K
V
R
Q
K
--
V
G
M
-
V
F
Q
-
H
F
N
-
L
F
P
H
L
T
A
I
E
N
I
T
L
-
A
P
V
K
V
K
K
-
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
---
L
L
D
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
-
V
M
K
Q
L
A
-
N
-
E
G
-
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
YRA
K
N
E
R
T
R
E
----
F
L
S
K
I
L
-------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
75.44
35%
-135
- C1 -
4YER
4
?
A:
[5-252]
---
I
I
V
V
E
N
L
V
K
K
F
G
D
----
F
E
A
V
K
G
V
S
F
S
V
K
K
G
E
I
F
A
F
L
G
P
N
G
A
G
K
T
T
T
I
H
M
L
T
T
L
L
K
P
T
S
G
K
A
W
V
A
G
---
H
D
----
V
L
K
E
-----
P
R
---
E
V
R
R
K
--
I
G
I
-
V
F
Q
D
Q
S
--
L
D
R
E
L
T
A
Y
E
N
M
Y
I
-
H
G
-
K
I
Y
G
-
Y
G
G
E
K
L
K
K
R
I
L
E
L
L
E
F
V
E
---
L
L
E
F
K
D
K
P
V
K
T
F
S
G
G
M
A
R
R
L
E
I
A
R
S
L
I
H
E
P
E
V
L
F
L
D
E
P
T
I
G
L
D
P
H
T
R
A
H
M
W
E
-
Y
I
S
K
M
K
-
K
-
E
H
-
N
M
T
I
F
L
T
T
H
Y
M
D
E
A
E
Q
L
A
D
R
V
A
I
I
D
H
G
K
I
I
A
L
G
T
P
T
E
L
----------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
74.48
30%
-134
- C1 -
4YMT
-
?
J:
[1-240]
---
M
I
F
V
N
D
V
Y
K
N
F
G
S
----
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
---
V
K
----
I
N
N
G
-----
K
V
NIN
K
V
R
Q
K
--
V
G
M
-
V
F
Q
-
H
F
N
-
L
F
P
H
L
T
A
I
E
N
I
T
L
-
A
P
V
K
V
K
K
-
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
---
L
L
D
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
-
V
M
K
Q
L
A
-
N
-
E
G
-
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
YRA
K
N
E
R
T
R
E
----
F
L
S
K
I
L
-------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
74.33
30%
-131
- C1 -
4YMV
1
?
J:
[1-240]
---
M
I
F
V
N
D
V
Y
K
N
F
G
S
----
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
---
V
K
----
I
N
N
G
-----
K
V
NIN
K
V
R
Q
K
--
V
G
M
-
V
F
Q
-
H
F
N
-
L
F
P
H
L
T
A
I
E
N
I
T
L
-
A
P
V
K
V
K
K
-
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
---
L
L
D
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
-
V
M
K
Q
L
A
-
N
-
E
G
-
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
YRA
K
N
E
R
T
R
E
----
F
L
S
K
I
L
-------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
73.79
30%
-133
- C1 -
4YMS
-
?
J:
[1-240]
---
M
I
F
V
N
D
V
Y
K
N
F
G
S
----
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
---
V
K
----
I
N
N
G
-----
K
V
NIN
K
V
R
Q
K
--
V
G
M
-
V
F
Q
-
H
F
N
-
L
F
P
H
L
T
A
I
E
N
I
T
L
-
A
P
V
K
V
K
K
-
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
---
L
L
D
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
-
V
M
K
Q
L
A
-
N
-
E
G
-
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
YRA
K
N
E
R
T
R
E
----
F
L
S
K
I
L
-------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
72.34
30%
-131
- C1 -
4YMW
-
?
J:
[1-240]
---
M
I
F
V
N
D
V
Y
K
N
F
G
S
----
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
---
V
K
----
I
N
N
G
-----
K
V
NIN
K
V
R
Q
K
--
V
G
M
-
V
F
Q
-
H
F
N
-
L
F
P
H
L
T
A
I
E
N
I
T
L
-
A
P
V
K
V
K
K
-
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
---
L
L
D
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
-
V
M
K
Q
L
A
-
N
-
E
G
-
M
-
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
YRA
K
N
E
R
T
R
E
----
F
L
S
K
I
L
-------------------------------------------------------------------------------------------------------------
47
Fugue
72.17
32%
-120
- C1 -
1Z47
1
?
A:
[11-355]
GSM
T
I
E
F
V
G
V
E
K
I
Y
P
G
G
A
R
S
---
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
----
K
----
R
V
T
D
-----
L
P
---
P
Q
K
R
N
--
V
G
L
-
V
F
Q
N
-
Y
A
-
L
F
Q
H
M
T
V
Y
D
N
V
S
F
-
G
L
-
R
E
K
R
-
V
P
K
D
E
M
D
A
R
V
R
E
L
L
R
F
M
R
---
L
E
S
Y
A
N
R
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
-
F
V
R
Q
V
H
-
D
-
E
M
G
V
-
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
E
V
Y
---
E
K
P
G
T
-----
L
F
V
A
S
F
I
G
E
S
N
V
W
T
R
A
V
Q
NG
R
I
E
V
AG
A
A
L
P
V
DPAVSEG
S
E
V
A
V
V
V
R
PKD
V
E
L
Q
P
A
S
EREAHAQVV
R
S
A
F
KGS
Y
S
A
C
W
I
R
T
KD
G
E
V
W
E
V
H
V
P
SADRHRWSPG
A
W
V
H
M
N
V
T
R
W
F
I
F
P
R
6
PsiBlast_PDB
72.11
30%
-139
- C1 -
3TUI
1
METN_ECOLI
C:
[24-257]
---
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
QE-
L
T
----
T
L
S
E
-----
S
E
---
L
T
K
A
R
RQ
I
G
M
-
I
F
Q
H
F
N
L
-
L
S
S
R
-
T
V
F
G
N
V
A
L
-
P
L
-
E
L
D
N
-
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
---
L
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
-
L
L
K
D
I
N
-
R
-
R
L
-
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
---
S
H
P
K
T
-------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
69.53
30%
-147
- C1 -
3TUZ
1
METN_ECOLI
C:
[24-257]
---
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
QE-
L
T
----
T
L
S
E
-----
S
E
---
L
T
K
A
R
RQ
I
G
M
-
I
F
Q
H
F
N
L
-
L
S
S
R
-
T
V
F
G
N
V
A
L
-
P
L
-
E
L
D
N
-
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
---
L
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
-
L
L
K
D
I
N
-
R
-
R
L
-
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
---
S
H
P
K
T
-------------------------------------------------------------------------------------------------------------------------
60
HHSearch
68.83
29%
-134
- C1 -
3TUI
1
METN_ECOLI
C:
[24-256]
---
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
---
Q
E
----
L
T
T
L
SESE-
L
T
---
K
A
R
R
Q
--
I
G
M
-
I
F
Q
H
F
-
N
-
L
L
S
S
R
T
V
F
G
N
V
A
L
-
P
L
-
E
L
D
N
-
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
---
L
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
-
L
L
K
D
I
N
-
R
R
L
G
-
L
-
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
---
S
H
P
K
--------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
68.20
33%
-125
- C1 -
1OXV
7
?
A:
[4-234]
----
I
I
V
K
N
V
S
K
V
F
--
K
K
G
K
V
V
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
---
R
L
----
V
A
S
N
GKLIV
P
P
---
E
-
D
R
K
--
I
G
M
-
V
F
Q
-
T
W
A
-
L
Y
P
N
L
T
A
F
E
N
I
A
F
-
P
L
-
T
N
M
K
-
M
S
K
E
E
I
R
K
R
V
E
E
V
A
K
I
L
D
---
I
H
H
V
L
N
H
F
P
R
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
-
L
V
K
E
V
Q
S
R
-
L
G
-
V
-
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
D
L
Y
---
D
N
P
V
S
-------------------------------------------------------------------------------------------------------------------------
69
HHSearch
67.67
29%
-145
- C1 -
4RVC
-
?
A:
[3-227]
---
L
L
E
V
K
D
L
S
G
G
Y
T
----
A
Q
N
V
L
E
D
V
T
F
V
V
D
R
G
E
M
V
A
L
I
G
L
N
G
A
G
K
S
T
T
I
K
H
I
I
G
L
M
E
P
R
R
G
A
I
S
I
N
G
---
Y
R
----
L
A
D
G
-----
P
E
---
T
Y
R
R
Q
--
F
A
Y
-
I
P
E
T
P
-
V
-
L
Y
E
E
L
T
L
E
E
H
L
R
L
-
A
A
-
M
A
Y
G
-
L
S
E
A
E
Y
E
R
R
L
P
P
L
L
R
E
F
R
---
L
E
R
R
L
S
S
F
P
A
H
F
S
K
G
M
K
Q
K
V
M
I
V
C
A
F
L
L
E
P
P
L
Y
I
I
D
E
P
F
L
G
L
D
P
L
A
I
H
A
L
L
E
-
R
M
N
E
Q
K
-
A
-
K
G
-
A
-
G
I
L
L
S
T
H
I
L
A
T
A
E
R
Y
C
D
S
F
V
I
L
H
N
G
R
V
K
A
K
G
T
L
D
D
I
R
---
R
Q
F
G
L
-------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
67.62
33%
-126
- C1 -
1OXU
7
?
A:
[4-234]
----
I
I
V
K
N
V
S
K
V
F
--
K
K
G
K
V
V
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
---
R
L
----
V
A
S
N
GKLIV
P
P
---
E
-
D
R
K
--
I
G
M
-
V
F
Q
-
T
W
A
-
L
Y
P
N
L
T
A
F
E
N
I
A
F
-
P
L
-
T
N
M
K
-
M
S
K
E
E
I
R
K
R
V
E
E
V
A
K
I
L
D
---
I
H
H
V
L
N
H
F
P
R
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
-
L
V
K
E
V
Q
S
R
-
L
G
-
V
-
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
D
L
Y
---
D
N
P
V
S
-------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
67.24
32%
-151
- C1 -
4RVC
-
?
A:
[19-221]
-----------------------
L
E
D
V
T
F
V
V
D
R
G
E
M
V
A
L
I
G
L
N
G
A
G
K
S
T
T
I
K
H
I
I
G
L
M
E
P
R
R
G
A
I
S
I
N
G
---
Y
R
----
L
A
D
G
-----
P
E
---
T
Y
R
R
Q
--
F
A
Y
-
I
--
P
E
T
P
V
L
Y
E
E
L
T
L
E
E
H
L
R
L
-
A
A
-
M
A
Y
G
-
L
S
E
A
E
Y
E
R
R
L
P
P
L
L
R
E
F
R
---
L
E
R
R
L
S
S
F
P
A
H
F
S
K
G
M
K
Q
K
V
M
I
V
C
A
F
L
L
E
P
P
L
Y
I
I
D
E
P
F
L
G
L
D
P
L
A
I
H
A
L
L
E
-
R
M
N
E
Q
K
-
A
-
K
G
-
A
-
G
I
L
L
S
T
H
I
L
A
T
A
E
R
Y
C
D
S
F
V
I
L
H
N
G
R
V
K
A
K
G
T
L
D
D
I
----------------------------------------------------------------------------------------------------------------------------------
44
Fugue
67.18
28%
-144
- C1 -
3TUZ
3
METN_ECOLI
H:
[23-362]
--H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
---
Q
E
LTTL
S
E
S
E
-----
L
T
---
K
A
R
R
Q
--
I
G
M
-
I
F
Q
-
H
F
N
-
L
L
S
S
R
T
V
F
G
N
V
A
L
-
P
L
-
E
L
D
N
-
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
---
L
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
-
L
L
K
D
I
N
-
R
-
R
L
-
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
---
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
T
L
H
L
D
I
P
EDYQERLQAEPFTDCVPMLRLEFTGQSVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHHVKVEV----------------
20
PsiBlast_PDB
66.78
29%
-150
- C1 -
3TUJ
-
METN_ECOLI
C:
[2-234]
----
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
QE-
L
T
----
T
L
S
E
-----
S
E
---
L
T
K
A
R
RQ
I
G
M
-
I
F
Q
H
F
N
L
-
L
S
S
R
-
T
V
F
G
N
V
A
L
-
P
L
-
E
L
D
N
-
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
---
L
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
-
L
L
K
D
I
N
-
R
-
R
L
-
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
---
S
H
P
K
T
-------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
66.77
33%
-129
- C1 -
1OXV
15
?
D:
[4-234]
----
I
I
V
K
N
V
S
K
V
F
--
K
K
G
K
V
V
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
---
R
L
----
V
A
S
N
GKLIV
P
P
---
E
-
D
R
K
--
I
G
M
-
V
F
Q
-
T
W
A
-
L
Y
P
N
L
T
A
F
E
N
I
A
F
-
P
L
-
T
N
M
K
-
M
S
K
E
E
I
R
K
R
V
E
E
V
A
K
I
L
D
---
I
H
H
V
L
N
H
F
P
R
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
-
L
V
K
E
V
Q
S
R
-
L
G
-
V
-
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
D
L
Y
---
D
N
P
V
S
-------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
66.42
33%
-128
- C1 -
1OXU
7
?
B:
[4-234]
----
I
I
V
K
N
V
S
K
V
F
--
K
K
G
K
V
V
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
---
R
L
----
V
A
S
N
GKLIV
P
P
---
E
-
D
R
K
--
I
G
M
-
V
F
Q
-
T
W
A
-
L
Y
P
N
L
T
A
F
E
N
I
A
F
-
P
L
-
T
N
M
K
-
M
S
K
E
E
I
R
K
R
V
E
E
V
A
K
I
L
D
---
I
H
H
V
L
N
H
F
P
R
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
-
L
V
K
E
V
Q
S
R
-
L
G
-
V
-
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
D
L
Y
---
D
N
P
V
S
-------------------------------------------------------------------------------------------------------------------------
31
PsiBlast_CBE
59.69
31%
-128
- C1 -
4P32
2
LPTB_ECOLI
A:
[16-227]
---------------------
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
---
D
D
----
I
S
L
L
-----
P
L
---
H
A
R
A
R
--
R
G
I
G
Y
L
P
Q
E
A
S
-
I
F
R
R
L
S
V
Y
D
N
L
M
A
-
V
L
-
Q
I
R
D
D
L
S
A
E
Q
R
E
D
R
A
N
E
L
M
E
E
F
H
IEH
L
R
D
S
M
G
Q
S
L
S
G
---
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
-
I
I
E
H
L
R
-
D
-
S
G
-
L
-
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
I
L
---
Q
D
E
---------------------------------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
58.80
31%
-129
- C1 -
4P32
2
LPTB_ECOLI
B:
[16-227]
---------------------
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
---
D
D
----
I
S
L
L
-----
P
L
---
H
A
R
A
R
--
R
G
I
G
Y
L
P
Q
E
A
S
-
I
F
R
R
L
S
V
Y
D
N
L
M
A
-
V
L
-
Q
I
R
D
D
L
S
A
E
Q
R
E
D
R
A
N
E
L
M
E
E
F
H
IEH
L
R
D
S
M
G
Q
S
L
S
G
---
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
-
I
I
E
H
L
R
-
D
-
S
G
-
L
-
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
I
L
---
Q
D
E
---------------------------------------------------------------------------------------------------------------------------
37
PsiBlast_CBE
48.54
31%
-117
- C1 -
3FVQ
3
FBPC_NEIG1
A:
[11-232]
----------
S
K
S
F
Q
N
----
T
P
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
KTI
F
S
----
K
N
T
N
-----
L
P
---
V
R
E
R
R
--
L
G
Y
-
L
V
-
Q
E
G
V
-
L
F
P
H
L
T
V
Y
R
N
I
A
Y
G
L
G
-
N
G
K
G
-
R
T
A
Q
E
-
R
Q
R
I
E
A
M
L
E
L
T
G
---
I
S
E
L
A
G
R
Y
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
-
A
-
N
G
-
K
-
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
G
R
I
L
Q
T
A
S
P
H
E
L
Y
---------------------------------------------------------------------------------------------------------------------------------
36
PsiBlast_CBE
45.69
31%
-117
- C1 -
3FVQ
3
FBPC_NEIG1
B:
[11-227]
----------
S
K
S
F
Q
N
----
T
P
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
KTI
F
S
----
K
N
T
N
-----
L
P
---
V
R
E
R
R
--
L
G
Y
-
L
V
-
Q
E
G
V
-
L
F
P
H
L
T
V
Y
R
N
I
A
Y
G
L
G
-
N
G
K
G
-
R
T
A
Q
E
-
R
Q
R
I
E
A
M
L
E
L
T
G
---
I
S
E
L
A
G
R
Y
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
-
A
-
N
G
-
K
-
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
G
R
I
L
Q
T
A
S
P
H
E
L
Y
---------------------------------------------------------------------------------------------------------------------------------