@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu02830: (2016-06-04 )
MYKDLTGKTAIVTGSSKGIGKAIAERFGKEKMNVVVNYHSDPSGADETLEIIKQNGGKAVSVEADVSKEEGIQALLDTALEHFGTLDVMVNNSGFNGVEAMPHEMSLEDWQRVIDVNVTGTFLGAKAALNHMMKNNIKGNVLNISSVHQQIPRPVNVQYSTSKGGIKMMTETLALNYADKGIRVNAIAPGTIATESNVDTKKEESRQKQLKKIPMKAFGKPEEVAAAAAWLVSEEASYVTGATLFVDGGMTLYPSQLE
Atome Classification :
(36 SA)
.........10........20........30........40........50....-----....60........70........80........90....-..-..100........110.......120.......130.......140.......150.......160.......170.......180.......190..---------.-....200.-.-.....210.-.......220.......230..-.....240.......250......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MYKDLTG
K
T
A
I
V
TGSSK
G
I
G
K
A
I
A
E
R
FGKE
K
M
N
V
V
V
N
YHSDPSG
A
D
E
T
L
E
I
I
K
QN-----GG
K
A
V
S
V
E
ADV
S
K
E
E
G
I
Q
A
L
L
D
T
A
L
E
HFG
T
L
D
V
M
V
NNSGF-N
G
-
V
EA-MPHEM
S
L
E
D
W
Q
R
V
I
D
VNVT
G
T
F
L
G
A
K
A
A
L
N
H
M
M
K
NNIKG
N
V
L
N
I
S
S
V
H
Q
QIPR
P
V
N
V
Q
Y
STSKG
G
I
K
M
M
T
E
T
L
A
L
NYADKG
I
R
V
N
A
IAPGTIAT---------E-SNVD
T
K
K
E
-
E
-
S
R
Q
K
Q
L
-
K
K-I
P
M
K
AFG
K
P
E
E
V
A
A
A
A
A
W
L
VSE-EASYVT
G
A
T
L
F
VDGG
M
T
LYPSQLE
2
PsiBlast_PDB
81.42
55%
-57
- C1 -
1RWB
1
DHG_BACME
A:
[1-255]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
-----
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
-
V
S
S
---
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
K
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
---------
P
-
I
N
A
E
K
F
A
D
P
E
-
Q
R
A
D
V
E
-
S
M
-
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
-
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
---
24
PsiBlast_CBE
80.74
55%
-56
- C1 -
1RWB
1
DHG_BACME
F:
[1-255]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
-----
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
-
V
S
S
---
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
K
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
---------
P
-
I
N
A
E
K
F
A
D
P
E
-
Q
R
A
D
V
E
-
S
M
-
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
-
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
---
26
PsiBlast_CBE
79.39
55%
-53
- C1 -
1RWB
1
DHG_BACME
B:
[1-255]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
-----
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
-
V
S
S
---
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
K
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
---------
P
-
I
N
A
E
K
F
A
D
P
E
-
Q
R
A
D
V
E
-
S
M
-
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
-
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
---
25
PsiBlast_CBE
78.97
55%
-57
- C1 -
1RWB
1
DHG_BACME
E:
[1-255]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
-----
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
-
V
S
S
---
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
K
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
---------
P
-
I
N
A
E
K
F
A
D
P
E
-
Q
R
A
D
V
E
-
S
M
-
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
-
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
---
27
PsiBlast_CBE
78.05
55%
-56
- C1 -
1GCO
1
DHG_BACME
F:
[1-255]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
-----
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
-
V
S
S
---
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
---------
P
-
I
N
A
E
K
F
A
D
P
E
-
Q
R
A
D
V
E
-
S
M
-
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
-
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
Q
Y
P
S
---
22
PsiBlast_CBE
77.71
55%
-57
- C1 -
1GEE
1
DHG_BACME
E:
[1-255]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
-----
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
-
V
S
S
---
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
---------
P
-
I
N
A
E
K
F
A
D
P
E
-
Q
R
A
D
V
E
-
S
M
-
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
-
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
---
23
PsiBlast_CBE
77.48
55%
-55
- C1 -
1GEE
1
DHG_BACME
B:
[1-255]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
-----
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
-
V
S
S
---
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
---------
P
-
I
N
A
E
K
F
A
D
P
E
-
Q
R
A
D
V
E
-
S
M
-
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
-
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
---
21
PsiBlast_CBE
77.41
55%
-56
- C1 -
1GEE
1
DHG_BACME
F:
[1-255]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
-----
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
-
V
S
S
---
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
---------
P
-
I
N
A
E
K
F
A
D
P
E
-
Q
R
A
D
V
E
-
S
M
-
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
-
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
---
3
PsiBlast_PDB
77.41
55%
-55
- C1 -
1GCO
1
DHG_BACME
A:
[1-255]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
-----
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
-
V
S
S
---
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
---------
P
-
I
N
A
E
K
F
A
D
P
E
-
Q
R
A
D
V
E
-
S
M
-
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
-
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
Q
Y
P
S
---
30
PsiBlast_CBE
77.21
55%
-58
- C1 -
1G6K
1
DHG_BACME
F:
[1-255]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
-----
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
A
N
P
-
V
S
S
---
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
---------
P
-
I
N
A
E
K
F
A
D
P
E
-
Q
R
A
D
V
E
-
S
M
-
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
-
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
Q
Y
P
S
---
1
PsiBlast_PDB
77.03
55%
-56
- C1 -
1GEE
1
DHG_BACME
A:
[1-255]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
-----
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
-
V
S
S
---
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
---------
P
-
I
N
A
E
K
F
A
D
P
E
-
Q
R
A
D
V
E
-
S
M
-
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
-
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
---
28
PsiBlast_CBE
76.97
55%
-56
- C1 -
1GCO
1
DHG_BACME
E:
[1-255]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
-----
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
-
V
S
S
---
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
---------
P
-
I
N
A
E
K
F
A
D
P
E
-
Q
R
A
D
V
E
-
S
M
-
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
-
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
Q
Y
P
S
---
29
PsiBlast_CBE
76.64
55%
-54
- C1 -
1GCO
1
DHG_BACME
B:
[1-255]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
-----
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
-
V
S
S
---
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
---------
P
-
I
N
A
E
K
F
A
D
P
E
-
Q
R
A
D
V
E
-
S
M
-
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
-
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
Q
Y
P
S
---
32
PsiBlast_CBE
76.63
55%
-56
- C1 -
1G6K
1
DHG_BACME
B:
[1-255]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
-----
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
A
N
P
-
V
S
S
---
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
---------
P
-
I
N
A
E
K
F
A
D
P
E
-
Q
R
A
D
V
E
-
S
M
-
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
-
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
Q
Y
P
S
---
31
PsiBlast_CBE
76.42
55%
-59
- C1 -
1G6K
1
DHG_BACME
E:
[1-255]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
-----
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
A
N
P
-
V
S
S
---
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
---------
P
-
I
N
A
E
K
F
A
D
P
E
-
Q
R
A
D
V
E
-
S
M
-
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
-
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
Q
Y
P
S
---
4
PsiBlast_PDB
75.33
55%
-56
- C1 -
1G6K
1
DHG_BACME
A:
[1-255]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
-----
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
A
N
P
-
V
S
S
---
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
---------
P
-
I
N
A
E
K
F
A
D
P
E
-
Q
R
A
D
V
E
-
S
M
-
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
-
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
Q
Y
P
S
---
111
HHSearch
75.13
55%
-52
- C1 -
1GEE
1
DHG_BACME
A:
[1-255]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
-----
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
-
E
N
-
P
V
--
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
---------
P
-
I
N
A
E
K
F
A
D
-
P
E
Q
R
A
D
V
E
-
S
M
-
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
-
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
---
9
PsiBlast_PDB
74.51
51%
-59
- C1 -
3AY6
3
DHG4_BACME
A:
[9-263]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
E
A
L
D
A
K
K
E
V
E
E
A
-----
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
-
V
P
S
---
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
---------
P
-
I
N
A
E
K
F
A
D
-
P
-
V
Q
R
A
D
V
-
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
-
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
---
13
PsiBlast_PDB
74.36
39%
-76
- C1 -
2UVD
-
?
A:
[2-246]
----
L
K
G
K
V
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
I
D
L
A
K
Q
G
A
N
V
V
V
N
Y
A
G
N
E
Q
K
A
N
E
V
V
D
E
I
K
K
L
-----
G
S
D
A
I
A
V
R
A
D
V
A
N
A
E
D
V
T
N
M
V
K
Q
T
V
D
V
F
G
Q
V
D
I
L
V
N
N
A
G
V
-
T
K
--
D
N
-
L
L
M
R
M
K
E
E
E
W
D
T
V
I
N
T
N
L
K
G
V
F
L
C
T
K
A
V
S
R
F
M
M
R
Q
R
-
H
G
R
I
V
N
I
A
S
V
V
G
V
T
G
N
P
G
Q
A
N
Y
V
A
A
K
A
G
V
I
G
L
T
K
T
S
A
K
E
L
A
S
R
N
I
T
V
N
A
I
A
P
G
F
I
A
T
---------
D
-
M
T
-
D
V
L
D
E
-
N
-
I
K
A
E
M
L
-
K
L
-
I
P
A
A
Q
F
G
E
A
Q
D
I
A
N
A
V
T
F
F
A
S
D
-
Q
S
K
Y
I
T
G
Q
T
L
N
V
D
G
G
M
V
M
------
37
PsiBlast_CBE
74.23
51%
-59
- C1 -
3AY6
3
DHG4_BACME
C:
[9-263]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
E
A
L
D
A
K
K
E
V
E
E
A
-----
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
-
V
P
S
---
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
---------
P
-
I
N
A
E
K
F
A
D
-
P
-
V
Q
R
A
D
V
-
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
-
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
---
38
PsiBlast_CBE
73.72
51%
-55
- C1 -
3AY6
3
DHG4_BACME
B:
[9-263]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
E
A
L
D
A
K
K
E
V
E
E
A
-----
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
-
V
P
S
---
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
---------
P
-
I
N
A
E
K
F
A
D
-
P
-
V
Q
R
A
D
V
-
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
-
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
---
35
PsiBlast_CBE
73.00
51%
-56
- C1 -
3AUT
1
DHG4_BACME
B:
[9-263]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
E
A
L
D
A
K
K
E
V
E
E
A
-----
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
-
V
P
S
---
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
---------
P
-
I
N
A
E
K
F
A
D
-
P
-
V
Q
R
A
D
V
-
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
-
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
---
34
PsiBlast_CBE
72.51
51%
-57
- C1 -
3AUU
1
DHG4_BACME
B:
[9-263]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
E
A
L
D
A
K
K
E
V
E
E
A
-----
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
-
V
P
S
---
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
---------
P
-
I
N
A
E
K
F
A
D
-
P
-
V
Q
R
A
D
V
-
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
-
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
---
8
PsiBlast_PDB
72.29
51%
-56
- C1 -
3AUU
1
DHG4_BACME
A:
[9-263]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
E
A
L
D
A
K
K
E
V
E
E
A
-----
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
-
V
P
S
---
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
---------
P
-
I
N
A
E
K
F
A
D
-
P
-
V
Q
R
A
D
V
-
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
-
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
---
36
PsiBlast_CBE
72.14
51%
-53
- C1 -
3AY6
3
DHG4_BACME
D:
[9-263]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
E
A
L
D
A
K
K
E
V
E
E
A
-----
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
-
V
P
S
---
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
---------
P
-
I
N
A
E
K
F
A
D
-
P
-
V
Q
R
A
D
V
-
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
-
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
---
63
PsiBlast_CBE
69.53
35%
-93
- C1 -
2DTE
1
?
B:
[3-248]
-
F
S
D
L
R
D
K
V
V
I
V
T
G
A
S
M
G
I
G
R
A
I
A
E
R
F
V
D
E
G
S
K
V
I
D
L
S
I
H
D
P
G
E
A
-----------------
K
Y
D
H
I
E
C
D
V
T
N
P
D
Q
V
K
A
S
I
D
H
I
F
K
E
Y
G
S
I
S
V
L
V
N
N
A
G
I
-
E
S
-
Y
G
K
-
I
-
E
S
M
S
M
G
E
W
R
R
I
I
D
V
N
L
F
G
Y
Y
Y
A
S
K
F
A
I
P
Y
M
I
R
S
R
-
D
P
S
I
V
N
I
S
S
V
Q
A
S
I
I
T
K
N
A
S
A
Y
V
T
S
K
H
A
V
I
G
L
T
K
S
I
A
L
D
Y
A
P
L
-
L
R
C
N
A
V
C
P
A
T
I
D
T
PLVRKAAEL
E
-
V
G
S
D
P
M
R
I
-
E
-
K
K
I
S
E
W
G
H
E
-
H
P
M
Q
R
I
G
K
P
Q
E
V
A
S
A
V
A
F
L
A
S
R
-
E
A
S
F
I
T
G
T
C
L
Y
V
D
G
G
L
S
I
------
64
PsiBlast_CBE
68.94
35%
-92
- C1 -
2DTE
1
?
A:
[3-248]
-
F
S
D
L
R
D
K
V
V
I
V
T
G
A
S
M
G
I
G
R
A
I
A
E
R
F
V
D
E
G
S
K
V
I
D
L
S
I
H
D
P
G
E
A
-----------------
K
Y
D
H
I
E
C
D
V
T
N
P
D
Q
V
K
A
S
I
D
H
I
F
K
E
Y
G
S
I
S
V
L
V
N
N
A
G
I
-
E
S
-
Y
G
K
-
I
-
E
S
M
S
M
G
E
W
R
R
I
I
D
V
N
L
F
G
Y
Y
Y
A
S
K
F
A
I
P
Y
M
I
R
S
R
-
D
P
S
I
V
N
I
S
S
V
Q
A
S
I
I
T
K
N
A
S
A
Y
V
T
S
K
H
A
V
I
G
L
T
K
S
I
A
L
D
Y
A
P
L
-
L
R
C
N
A
V
C
P
A
T
I
D
T
P
L
V
R
K
A
A
E
L
E
-
V
G
S
D
P
M
R
I
-
E
-
K
K
I
S
E
W
G
H
E
-
H
P
M
Q
R
I
G
K
P
Q
E
V
A
S
A
V
A
F
L
A
S
R
-
E
A
S
F
I
T
G
T
C
L
Y
V
D
G
G
L
S
I
------
72
PsiBlast_CBE
68.85
38%
-82
- C1 -
2CFC
2
HCDR_XANP2
C:
[3-248]
-------
R
V
A
I
V
T
G
A
S
S
G
N
G
L
A
I
A
T
R
F
L
A
R
G
D
R
V
A
A
---
L
D
L
S
A
--
E
T
L
E
E
T
A
R
T
HWHAY
A
D
K
V
L
R
V
R
A
D
V
A
D
E
G
D
V
N
A
A
I
A
A
T
M
E
Q
F
G
A
I
D
V
L
V
N
N
A
G
I
-
T
G
N
S
E
A
G
V
L
H
T
T
P
V
E
Q
F
D
K
V
M
A
V
N
V
R
G
I
F
L
G
C
R
A
V
L
P
H
M
L
L
Q
G
-
A
G
V
I
V
N
I
A
S
V
A
S
L
V
A
F
P
G
R
S
A
Y
T
T
S
K
G
A
V
L
Q
L
T
K
S
V
A
V
D
Y
A
G
S
G
I
R
C
N
A
V
C
P
G
M
I
E
T
---------
P
M
T
Q
W
R
L
D
Q
P
-
E
-
L
R
D
Q
V
L
-
A
R
-
I
P
Q
K
E
I
G
T
A
A
Q
V
A
D
A
V
M
F
L
A
G
E
-
D
A
T
Y
V
N
G
A
A
L
V
M
D
G
A
Y
T
-------
51
PsiBlast_CBE
68.01
39%
-88
- C1 -
4DMM
1
?
C:
[26-268]
----
L
T
D
R
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
L
E
L
A
A
A
G
A
K
V
A
V
N
Y
A
S
S
A
G
A
A
D
E
V
V
A
A
I
A
A
A
-----
G
G
E
A
F
A
V
K
A
D
V
S
Q
E
S
E
V
E
A
L
F
A
A
V
I
E
R
W
G
R
L
D
V
L
V
N
N
A
G
I
-
T
--
R
D
T
-
L
L
L
R
M
K
R
D
D
W
Q
S
V
L
D
L
N
L
G
G
V
F
L
C
S
R
A
A
A
K
I
M
L
K
Q
R
-
S
G
R
I
I
N
I
A
S
V
V
G
E
M
G
N
P
G
Q
A
N
Y
S
A
A
K
A
G
V
I
G
L
T
K
T
V
A
K
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
F
I
A
T
--------------
D
M
--------
E
K
L
L
-
E
V
-
I
P
L
G
R
Y
G
E
A
A
E
V
A
G
V
V
R
F
L
A
A
D
P
A
A
A
Y
I
T
G
Q
V
I
N
I
D
G
G
L
V
M
------
50
PsiBlast_CBE
67.45
39%
-87
- C1 -
4DMM
1
?
D:
[26-268]
----
L
T
D
R
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
L
E
L
A
A
A
G
A
K
V
A
V
N
Y
A
S
S
A
G
A
A
D
E
V
V
A
A
I
A
A
A
-----
G
G
E
A
F
A
V
K
A
D
V
S
Q
E
S
E
V
E
A
L
F
A
A
V
I
E
R
W
G
R
L
D
V
L
V
N
N
A
G
I
-
T
--
R
D
T
-
L
L
L
R
M
K
R
D
D
W
Q
S
V
L
D
L
N
L
G
G
V
F
L
C
S
R
A
A
A
K
I
M
L
K
Q
R
-
S
G
R
I
I
N
I
A
S
V
V
G
E
M
G
N
P
G
Q
A
N
Y
S
A
A
K
A
G
V
I
G
L
T
K
T
V
A
K
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
F
I
A
T
-------------------------
K
L
L
-
E
V
-
I
P
L
G
R
Y
G
E
A
A
E
V
A
G
V
V
R
F
L
A
A
D
P
A
A
A
Y
I
T
G
Q
V
I
N
I
D
G
G
L
V
M
------
73
PsiBlast_CBE
67.10
38%
-82
- C1 -
2CFC
2
HCDR_XANP2
B:
[3-248]
-------
R
V
A
I
V
T
G
A
S
S
G
N
G
L
A
I
A
T
R
F
L
A
R
G
D
R
V
A
A
---
L
D
L
S
A
--
E
T
L
E
E
T
A
R
T
HWHAY
A
D
K
V
L
R
V
R
A
D
V
A
D
E
G
D
V
N
A
A
I
A
A
T
M
E
Q
F
G
A
I
D
V
L
V
N
N
A
G
I
-
T
G
N
S
E
A
G
V
L
H
T
T
P
V
E
Q
F
D
K
V
M
A
V
N
V
R
G
I
F
L
G
C
R
A
V
L
P
H
M
L
L
Q
G
-
A
G
V
I
V
N
I
A
S
V
A
S
L
V
A
F
P
G
R
S
A
Y
T
T
S
K
G
A
V
L
Q
L
T
K
S
V
A
V
D
Y
A
G
S
G
I
R
C
N
A
V
C
P
G
M
I
E
T
---------
P
M
T
Q
W
R
L
D
Q
P
-
E
-
L
R
D
Q
V
L
-
A
R
-
I
P
Q
K
E
I
G
T
A
A
Q
V
A
D
A
V
M
F
L
A
G
E
-
D
A
T
Y
V
N
G
A
A
L
V
M
D
G
A
Y
T
-------
74
PsiBlast_CBE
66.59
38%
-81
- C1 -
2CFC
2
HCDR_XANP2
A:
[3-248]
-------
R
V
A
I
V
T
G
A
S
S
G
N
G
L
A
I
A
T
R
F
L
A
R
G
D
R
V
A
A
---
L
D
L
S
A
--
E
T
L
E
E
T
A
R
T
HWHAY
A
D
K
V
L
R
V
R
A
D
V
A
D
E
G
D
V
N
A
A
I
A
A
T
M
E
Q
F
G
A
I
D
V
L
V
N
N
A
G
I
-
T
G
N
S
E
A
G
V
L
H
T
T
P
V
E
Q
F
D
K
V
M
A
V
N
V
R
G
I
F
L
G
C
R
A
V
L
P
H
M
L
L
Q
G
-
A
G
V
I
V
N
I
A
S
V
A
S
L
V
A
F
P
G
R
S
A
Y
T
T
S
K
G
A
V
L
Q
L
T
K
S
V
A
V
D
Y
A
G
S
G
I
R
C
N
A
V
C
P
G
M
I
E
T
---------
P
M
T
Q
W
R
L
D
Q
P
-
E
-
L
R
D
Q
V
L
-
A
R
-
I
P
Q
K
E
I
G
T
A
A
Q
V
A
D
A
V
M
F
L
A
G
E
-
D
A
T
Y
V
N
G
A
A
L
V
M
D
G
A
Y
T
-------
52
PsiBlast_CBE
64.96
39%
-81
- C1 -
4DMM
1
?
B:
[26-268]
----
L
T
D
R
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
L
E
L
A
A
A
G
A
K
V
A
V
N
Y
A
S
S
A
G
A
A
D
E
V
V
A
A
I
A
A
A
-----
G
G
E
A
F
A
V
K
A
D
V
S
Q
E
S
E
V
E
A
L
F
A
A
V
I
E
R
W
G
R
L
D
V
L
V
N
N
A
G
I
-
T
--
R
D
T
-
L
L
L
R
M
K
R
D
D
W
Q
S
V
L
D
L
N
L
G
G
V
F
L
C
S
R
A
A
A
K
I
M
L
K
Q
R
-
S
G
R
I
I
N
I
A
S
V
V
G
E
M
G
N
P
G
Q
A
N
Y
S
A
A
K
A
G
V
I
G
L
T
K
T
V
A
K
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
F
I
A
T
--------------
D
M
T
S
--------
L
L
-
E
V
-
I
P
L
G
R
Y
G
E
A
A
E
V
A
G
V
V
R
F
L
A
A
D
P
A
A
A
Y
I
T
G
Q
V
I
N
I
D
G
G
L
V
M
------
47
PsiBlast_CBE
64.04
40%
-65
- C1 -
4URE
5
?
B:
[3-244]
----
L
E
G
K
T
A
L
V
T
G
A
G
N
G
I
G
R
T
I
A
L
T
Y
A
A
E
G
A
N
V
V
V
S
D
I
S
D
E
W
G
-
R
E
T
L
A
L
I
E
G
K
-----
G
G
K
A
V
F
Q
H
A
D
T
A
H
P
E
D
H
D
E
L
I
A
A
A
K
R
A
F
G
R
L
D
I
A
C
N
N
A
G
I
-
S
G
-
E
F
T
-
P
T
A
E
T
T
D
A
Q
W
Q
R
V
I
G
I
N
L
S
G
V
F
Y
G
V
R
A
Q
I
R
A
M
L
E
T
G
-
G
G
A
I
V
N
I
S
S
I
A
G
Q
I
G
I
E
G
I
T
P
Y
T
A
A
K
H
G
V
V
G
L
T
K
T
V
A
W
E
Y
G
S
K
G
I
R
I
N
S
V
G
P
A
F
I
N
T
-----------
T
L
V
Q
N
V
P
L
-
E
-
T
R
R
Q
L
E
-
Q
M
-
H
A
L
R
R
L
G
E
T
E
E
V
A
N
L
V
A
W
L
S
S
D
-
K
A
S
F
V
T
G
S
Y
Y
A
V
D
G
G
---------
93
PsiBlast_CBE
59.56
35%
-71
- C1 -
3RRO
11
FABG_VIBCH
A:
[7-250]
-
F
M
N
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
-
E
R
G
A
K
V
I
G
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
G
D
N
-----
G
-
K
G
M
A
L
--
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
G
G
V
D
I
L
V
N
N
A
G
I
-
T
--
R
D
N
-
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
-
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
---------
D
-
M
-
T
K
A
L
N
D
-
E
-
Q
R
T
A
T
L
-
A
Q
-
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
S
P
-
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
------
92
PsiBlast_CBE
58.97
35%
-73
- C1 -
3RRO
13
FABG_VIBCH
B:
[7-250]
-
F
M
N
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
-
E
R
G
A
K
V
I
G
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
G
D
N
-----
G
-
K
G
M
A
L
--
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
G
G
V
D
I
L
V
N
N
A
G
I
-
T
--
R
D
N
-
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
-
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
---------
D
-
M
-
T
K
A
L
N
D
-
E
-
Q
R
T
A
T
L
-
A
Q
-
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
S
P
-
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
------