@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu02920: (2016-06-05 )
MDFLHHILSTYASFFDWKMWGEVLTDPVSWGLIGSLVVLEGLLSADNALVLAVMVKHLPEKQRKKALTYGLFGAYIFRFIFIGLGMLLIKFWWIKVLGALYLAWLVIKHFWIGEKEEEADGMKKNSWMVRTFGIFWATVISVELMDLAFSVDSILAAFAVSEKVWVLLIGGMLGILMMRTVAKVFLVLIDKIPELENTAFVLIGIIALKMAGSAFHYEMPHSVFFIIIIAAFAVTLIIHYINKQKQVREQTAASKEE
Atome Classification :
(15 SA)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10....-....20........30........40........50-----.........60........70......--------------..80...--------.....90.......--------.100.....------------.--.110....--------------...120.......130----------...---.--....140-------......----.150.-..--------....160...----------....170----------......--...180.......190----------.-------........200---------.-------.......210.......----220.......230.......240.......250.....--------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
F
L
H
H
I
L
S
T
Y
A
S
F
F
-
D
W
K
M
W
G
E
V
LTDPV
S
W
G
L
I
G
S
L
V
V
L
E
G
L
LSAD
N
A
L
V
------
L
A
V
M
V
K
HL
P
E
K
Q
R
K
K
A
L
T
Y
G
L
F
G
A
Y
I
F
--------------
R
F
I
F
I
G
L
--------
G
M
L
L
I
K
F
W
W
I
K
V
L
G
--------
A
L
Y
L
A
W
L
V
I
------------
K
--
H
F
WIGE
K
E
--------------
E
E
ADGMKKN
S
W
M
V
R
T
-----------
F
G
I
---
F
--
W
A
T
V
I
S
V
-------
E
L
M
D
L
A
----
F
S
V
D
S
-
I
L
--------
A
A
F
A
VSE
K
V
W
----------
V
L
L
I
G
------------
G
M
L
G
I
L
--
M
M
R
T
V
A
K
V
F
L
V
L
I
D
------------K-------IPELEN
T
A
F
V
----------
L
-------
I
G
I
I
A
L
K
MAGS
A
F
H
YEM----P
H
S
V
F
F
I
I
I
I
A
A
F
A
V
T
L
I
I
H
Y
I
N
K
Q
K
Q
V
R
E
Q
TAASKEE--------------------------------------------------------------------
15
Fugue
66.21
18%
-126
- C5 -
4R1D
-
?
B:
[1-301]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
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K
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C
F
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P
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A
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A
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Y
Y
L
W
G
--
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R
I
E
Y
L
D
-----
D
K
P
T
E
------
L
A
A
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V
D
R
L
E
Q
E
W
R
T
Q
--
R
H
K
S
K
G
N
M
F
L
--------------
R
K
I
D
F
G
N
--------
E
S
V
G
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E
V
A
S
--------
K
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Y
L
L
D
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P
T
W
H
V
Y
R
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K
G
--
K
V
S
V
D
R
E
Q
--------------
H
A
V
E
I
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R
A
L
A
R
N
L
R
S
R
A
PKEIPS
E
P
G
F
C
I
---
D
--
H
A
Y
I
A
G
D
-------
S
F
Q
V
E
R
----
F
G
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G
V
-
T
F
--------
P
E
H
P
G
A
R
F
E
F
----------
R
S
S
T
G
------------
A
E
L
N
S
L
--
L
E
R
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N
M
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F
AGMETL
R
K
G
K
H
P
-------
V
G
S
L
P
G
E
E
Y
L
----------
V
-------
A
G
S
D
K
-
G
Q
R
G
Y
T
F
M
W
E
V
QGK-
E
E
S
L
T
E
P
N
L
T
A
G
L
A
V
---
L
E
R
S
N
E
N
G
K
P
P
P
P
A
F
K
S
D
K
E
A
L
E
L
W
D
T
I
V
D
S
IRVRPTS--------------------------------------------------
11
Fugue
59.23
14%
-188
* C8 *
3H5N
5
?
A:
[4-350]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
---
Y
I
L
G
R
Y
V
K
I
A
-
R
Y
G
S
G
G
L
V
G
G
G
G
K
E
-
Q
Y
V
E
N
L
V
L
W
E
N
I
I
K
T
A
Y
C
F
I
TPSS
Y
T
A
A
L
E
T
A
N
I
P
E
K
D
F
S
N
C
F
R
F
L
K
E
N
F
F
I
I
PGEYNNSTENNRY
S
R
N
F
L
H
Y
Q
S
Y
GAN
P
V
L
V
Q
D
K
L
K
N
A
K
V
V
I
L
G
CG
G
I
G
N
H
V
S
V
I
L
A
T
S
G
I
------------
G
--
E
I
I
L
I
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N
D
Q
I
E
NTNLTRQVLFS
E
D
D
V
G
K
N
K
T
E
V
I
K
R
E
-----------
L
L
K
---
R
NS
E
I
S
V
S
E
I
ALNINDY
T
D
L
H
K
V
----
P
E
A
D
I
-
W
V
VSADHPFN
L
I
N
W
V
N
K
Y
C
V
R
A
N
Q
P
Y
I
N
A
G
Y
V
N
D
I
------------
A
V
F
G
P
L
--
Y
V
P
G
K
T
G
C
Y
E
C
Q
K
K
------------
E
-------
N
I
D
H
K
I
K
L
I
N
S
R
FKPATF
A
P
V
-------
N
N
V
A
A
A
L
C
A
A
D
V
I
K
F
I
G
KYSE
P
L
S
L
N
K
R
I
G
I
W
S
D
E
I
K
I
H
S
Q
N
M
G
R
S
P
V
C
S
V
C
G
--------------------------------------------------------------------------
8
Fugue
56.98
21%
-172
* C6 *
4IWS
-
FDC_PSEAE
A:
[23-515]
M
N
R
S
A
L
D
F
R
H
F
V
D
H
L
R
R
Q
GD
L
V
D
V
HTEVDANL
E
I
G
A
I
T
R
R
V
Y
E
R
RA
P
A
P
L
F
HNIRDSLPG
A
R
V
L
G
APAGLRADRARAH
S
R
L
A
L
H
F
GLPEHSG
P
R
D
I
V
A
M
L
R
A
A
M
R
A
E
P
I
APRRLERGPVQE
N
V
W
L
GEQVDLTRFPVPLLHEQDGGRYFGTY
G
F
H
V
V
Q
T
PDGS
W
D
S
W
S
V
G
R
L
M
L
V
D
RN
T
L
A
G
P
T
I
PTQ
H
I
G
I
I
R
E
Q
W
R
R
L
GK
P
T
P
W
A
M
A
L
GAP
P
A
A
L
A
A
A
G
MPLPEGVSE
A
G
Y
V
G
A
L
V
G
E
P
V
E
V
V
-
R
T
Q
T
N
G
-------
L
W
V
P
A
N
T
E
I
V
L
E
G
E
I
S
L
D
E
T
A
L
------
E
------------------
G
P
M
G
E
Y
H
G
--------------
Y
S
F
P
I
G
K
--------
P
Q
P
L
F
H
V
H
A
L
S
F
R
D
--------
Q
P
I
L
P
I
C
V
A
-------------------
G
T
P
P
--------------
E
E
N
H
T
I
-----------------------------
W
G
T
M
I
S
A
-------
Q
L
L
D
V
A
Q
N
A
G
L
P
V
D
M
-
V
W
--------
C
S
Y
E
A
A
T
C
W
A
----------
V
L
S
I
D
--------------------------------
V
Q
------------
R
-------
L
A
A
L
G
T
D
A
A
A
----------
F
-------
A
A
R
V
A
E
T
V
F
G
S
----
H
A
----
G
H
L
V
P
K
L
I
L
V
G
N
D
I
D
V
T
E
I
D
Q
V
V
W
A
L
A
T
R
A
H
P
L
H
D
H
F
A
FPQIRDFPMVPYLD
A
E
D
K
A
R
GSGG
R
L
V
I
N
CLY
P
E
Q
F
A
GQMRAATASFRHAYP
T
A
L
R
R
R
V
E
E
R
W
SDYGF
12
Fugue
55.31
17%
-176
- C8 -
1W24
-
VPS29_HUMAN
A:
[1-182]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
L
V
L
V
L
G
D
L
H
I
P
H
R
C
N
S
------
L
P
A
K
F
K
K
L
L
V
P
G
K
------------
I
Q
--------------
H
I
L
C
T
G
N
-----------
L
C
T
K
E
S
Y
D
Y
L
K
--------
T
L
A
G
D
V
H
I
V
------------
R
------
G
D
F
D
--------------
E
N
L
N
Y
P
E
Q
K
V
V
T
V
G
Q
-----------
F
K
I
---
G
--
L
I
H
-------------
G
H
Q
V
----
I
P
D
M
A
-
S
L
--------
A
L
L
Q
R
Q
F
D
V
D
----------
I
L
I
S
G
------------
H
-----------------
T
H
K
F
------------
E
-------
A
F
E
H
E
N
K
F
Y
I
----------
N
-------
P
G
S
A
T
G
A
Y
N
A
L
E
---
T
N
----
I
I
P
S
F
V
L
M
D
I
Q
A
S
T
V
V
T
Y
V
Y
Q
L
I
G
D
D
V
K
V
E
R
I
E
Y
K
K
P
---------------------------------------------------------------------
14
Fugue
54.24
11%
-152
- C4 -
2YYE
8
SELD_AQUAE
A:
[3-345]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGIMVELLKLVRSSGCAAKVGP
G
D
L
Q
E
I
L
K
G
FNIYTDESTLVSIG
D
D
A
G
V
Y
E
H
N
G
I
I
W
V
Y
-
T
V
D
I
I
T
P
V
V
N
D
P
Y
L
W
G
A
I
S
T
A
N
A
L
S
D
V
Y
A
M
G
G
I
P
V
------
N
A
L
A
I
S
C
F
N
N
C
E
L
D
I
E
I
F
R
E
V
I
R
G
A
L
D
--------------
K
L
R
E
A
K
T
------------
V
L
L
G
G
H
T
I
D
D
--------
K
E
P
K
F
G
L
S
V
------------
A
--
G
I
C
P
E
G
K
Y
--------------
I
T
Q
S
G
A
Q
V
G
Q
L
L
I
L
T
-----------
K
P
I
G
T
G
I
--
L
I
K
G
L
K
E
-------
G
I
L
K
E
E
----
D
I
N
E
A
-
I
E
--------
N
M
L
A
L
N
D
K
A
R
----------
N
L
M
L
S
L
DAT
A
C
T
D
V
T
GF
G
L
L
G
H
A
W
N
I
C
K
N
S
N
I
G
A
R
I
F
F
E
------------
K
-------
V
P
Y
Y
Q
L
S
E
N
L
----------
V
K
K
K
I
Y
P
K
G
A
I
E
N
L
N
F
V
K
N
Y
L
K
S
N
L
----
D
N
W
K
L
I
L
L
S
D
P
V
T
S
G
G
L
L
F
T
I
N
K
E
K
L
E
K
I
D
E
T
A
K
E
L
E
V
N
Y
W
II
G
E
T
I
AEN
V
L
E
V
L---------------------------------------------------
13
Fugue
49.55
12%
-140
- C3 -
4CLC
-
YBY7_YEAST
A:
[2-170]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
V
L
D
K
K
L
------
L
E
R
L
T
S
R
K
V
P
L
E
E
L
E
D
M
E
K
R
C
F
L
S
T
F
T
--------------
Y
Q
D
A
F
D
L
--------
G
T
Y
I
R
N
A
V
K
E
N
F
P
E
--------
K
P
V
A
I
D
I
S
L
------------
P
NG
H
C
L
F
R
T
V
T
--------------
Y
G
G
S
A
L
D
N
D
F
W
I
Q
R
K
-----------
K
K
T
---
A
--
L
R
F
G
H
S
S
-------
F
Y
M
G
C
K
----
K
G
D
K
T
-
P
E
--------
E
K
F
F
V
D
S
K
E
Y
----------
A
F
H
-
G
------------
G
A
V
L
I
Q
--
S
E
R
S
D
Y
P
Y
A
C
L
T
I
S
------------
G
-------
L
K
Q
E
E
D
H
L
M
A
----------
L
-------
S
S
L
I
A
F
A
N
E
----------------------------------------------------------------------------------------------------------------------
3
HHSearch
33.87
15%
-200
- C7 -
5AJI
1
MSCS_ECOLI
A:
[35-93]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
I
------------
I
I
V
G
L
I
--
I
A
R
M
I
S
N
A
V
N
R
L
M
I
------------
S
R
KIDATV
A
-
F
L
S
A
L
V
R
Y
----------
G
-------
I
I
A
F
T
L
I
A
A
L
G
R
V
G
V
Q
T
--------------------------------------------------------------------------------------------------------------
7
Fugue
30.67
19%
-122
- C7 -
2GV5
-
SFI1_YEAST
C:
[638-710]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
--------
P
L
G
S
K
L
N
D
I
------------
L
--
H
V
Y
E
K
S
K
E
--------------
R
E
L
Q
S
Q
L
F
N
A
W
R
N
R
------------
F
C
F
---
Y
--
T
E
E
C
N
I
Q
-------
A
I
S
K
R
N
----
Y
Q
L
E
K
M
V
L
--------
K
K
F
R
E
R
L
L
E
I
----------
V
K
S
E
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
30.51
50%
141
- C2 -
2KE4
-
A:
[337-346]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
L
P
P
E
Q
Q
R
K
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
28.88
31%
-263
- C7 -
2L9U
-
ERBB3_HUMAN
A:
[656-671]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
M
M
L
G
--------
G
T
F
L
Y
W
R
G
R
------------
R
--
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
Fugue
24.95
21%
58
* C7 *
1ETF
-
REV_HV1W2
B:
[1-23]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
T
R
Q
A
------
R
R
N
R
R
R
R
W
R
E
R
Q
R
A
A
A
A
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
HHSearch
24.87
18%
-119
- C7 -
2K21
-
KCNE1_HUMAN
A:
[55-76]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
F
F
T
L
G
I
M
L
S
Y
I
R
S
K
K
L
E
H
S
N
D
--------------------------------------------------------------------------
1
HHSearch
24.47
5%
-160
- C7 -
2M0Q
-
KCNE2_HUMAN
A:
[61-82]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
F
I
I
V
A
I
L
V
S
T
V
K
S
K
R
R
E
H
S
N
D
--------------------------------------------------------------------------
9
Fugue
17.59
25%
56
- C6 -
4PVZ
-
HEH2_YEAST
C:
[97-131]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
S
T
N
K
R
K
R
E
Q
I
S
T
D
N
E
A
K
------
M
Q
I
Q
E
E
K
S
P
K
K
K
R
K
K
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
16.38
25%
305
- C1 -
1PJN
-
A:
[3-14]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
R
K
T
E
E
E
S
P
L
K
D
---------------------------------------------------------------------