@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu02980: (2016-06-05 )
MSVDEKPIKIKVEKVSKIFGKQTKKAVQMLANGKTKKEILKATGSTVGVNQADFEVYDGEIFVIMGLSGSGKSTLVRMLNRLIEPTAGNIYIDGDMITNMSKDQLREVRRKKISMVFQKFALFPHRTILENTEYGLELQGVDKQERQQKALESLKLVGLEGFEHQYPDQLSGGMQQRVGLARALTNDPDILLMDEAFSALDPLIRKDMQDELLDLHDNVGKTIIFITHDLDEALRIGDRIVLMKDGNIVQIGTPEEILMNPSNEYVEKFVEDVDLSKVLTAGHIMKRAETVRIDKGPRVALTLMKNLGISSIYAVDKQKKLLGVIYASDAKKAAESDLSLQDILNTEFTTVPENTYLTEIFDVVSDANIPIAVVDEKQRMKGIVVRGALIGALAGNNEYINAEGTNEQTQDPSAQEVK
Atome Classification :
(26 SA)
.........10........20........30........40........50........60........70........80........90........100---------........110......--.120.......130.-....-...140.......150.-......-160.......170.......180.......190.......200.......210.......---220.......230.......240.......250.......260.......270......-.280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MSVDEK
P
I
K
I
K
V
E
K
V
S
K
I
F
G
K
Q
T
K
K
A
V
Q
M
L
ANGK
T
K
K
E
I
L
K
ATGSTVGVNQA
D
F
E
V
YD
G
E
I
F
V
I
M
GLSGS
G
K
S
T
L
V
R
M
L
N
R
LIEPTAG
N
I
Y
IDGDMITNM
S
----------
K
D
Q
L
R
E
V
R
R
K
K
I
S
M
V
F
Q
--
K
F
ALFPH
R
T
I
LEN-T-EYG
L
-
E
L
QGV
D
K
Q
E
R
Q
Q
K
A
L
E
S
-
L
K
L
VGL-EGFEHQY
P
D
Q
LSG
G
M
Q
Q
R
V
G
L
A
R
ALTNDP
D
I
L
L
M
D
E
A
F
S
A
L
D
P
L
I
R
K
D
M
Q
D
E
L
L
D
L
H
DNV---G
K
T
I
I
F
I
THD
L
D
E
A
L
RIG
D
R
I
V
L
M
KDG
N
I
V
Q
IG
T
P
E
E
ILMNP
S
N
E
Y
V
E
K
F
V
E
DV
D
L
S
K
V
-
L
T
A
G
H
I
M
KRA
E
T
V
RIDKGP
R
V
A
L
T
L
M
K
NLGIS
S
I
Y
AVDKQK
K
L
L
G
V
I
YAS
D
A
K
K
A
A
ESDL
S
L
Q
D
I
LNTEFTTVPEN
T
Y
L
T
E
I
F
D
V
VSDANI
P
I
A
VVD
E
K
Q
R
M
K
G
I
V
V
R
G
A
L
I
G
A
LAGNN
E
Y
I
NAEGTNEQTQDPSAQEVK
127
HHSearch
83.20
39%
-123
- C2 -
1V43
-
?
A:
[9-252]
-----
K
M
V
E
V
K
L
E
N
L
T
K
R
F
G
N
F
------------------------
T
A
V
N
K
L
N
L
T
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
E
E
P
T
E
G
R
I
Y
F
G
D
R
D
V
T
Y
L
P
----------
P
K
------
D
R
N
I
S
M
V
F
Q
--------
H
M
T
V
Y
E
N
-
I
-
A
F
P
L
---
K
K
F
P
K
D
E
I
D
K
R
V
R
W
A
-
A
E
L
L
Q
I
-
E
E
L
L
N
R
Y
P
A
Q
L
S
G
G
Q
R
Q
R
V
A
V
A
R
A
I
V
V
E
P
D
V
L
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
A
M
R
A
E
I
K
K
L
Q
Q
K
L
---
K
V
T
T
I
Y
V
T
H
D
Q
V
E
A
M
T
M
G
D
R
I
A
V
M
N
R
G
Q
L
L
Q
I
G
S
P
T
E
V
Y
L
R
P
N
S
V
F
V
A
T
F
I
G
A
P
--------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
81.49
42%
-118
- C2 -
4YMT
-
?
J:
[6-240]
-------------------------------------
D
V
Y
K
N
F
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
N
N
-
G
----------
K
V
N
I
N
K
V
R
Q
K
-
V
G
M
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
-
L
A
P
V
-
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
-
L
A
K
V
G
L
-
L
D
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
E
---
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
-----
L
S
K
I
-
L
-------------------------------------------------------------------------------------------------------------------------------------------
133
HHSearch
81.32
37%
-129
- C2 -
3TUI
1
METN_ECOLI
C:
[23-266]
-------
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
--------------------
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
----------
E
S
E
L
T
K
A
-
R
R
Q
I
G
M
I
F
Q
--
H
F
N
L
L
S
S
R
T
V
F
G
N
-
V
-
A
L
P
L
-
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
-
L
S
L
V
G
L
-
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
---
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
---------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
80.71
42%
-118
- C2 -
4YMU
2
?
A:
[6-240]
-------------------------------------
D
V
Y
K
N
F
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
N
N
-
G
----------
K
V
N
I
N
K
V
R
Q
K
-
V
G
M
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
-
L
A
P
V
-
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
-
L
A
K
V
G
L
-
L
D
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
E
---
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
-----
L
S
K
I
-
L
-------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
80.54
42%
-116
- C2 -
4YMV
1
?
J:
[6-240]
-------------------------------------
D
V
Y
K
N
F
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
N
N
-
G
----------
K
V
N
I
N
K
V
R
Q
K
-
V
G
M
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
-
L
A
P
V
-
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
-
L
A
K
V
G
L
-
L
D
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
E
---
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
-----
L
S
K
I
-
L
-------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
80.31
42%
-115
- C2 -
4YMV
1
?
A:
[6-240]
-------------------------------------
D
V
Y
K
N
F
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
N
N
-
G
----------
K
V
N
I
N
K
V
R
Q
K
-
V
G
M
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
-
L
A
P
V
-
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
-
L
A
K
V
G
L
-
L
D
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
E
---
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
-----
L
S
K
I
-
L
-------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
79.88
42%
-114
- C2 -
4YMU
2
?
J:
[6-240]
-------------------------------------
D
V
Y
K
N
F
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
N
N
-
G
----------
K
V
N
I
N
K
V
R
Q
K
-
V
G
M
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
-
L
A
P
V
-
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
-
L
A
K
V
G
L
-
L
D
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
E
---
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
-----
L
S
K
I
-
L
-------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
79.74
36%
-127
- C2 -
3TUZ
1
METN_ECOLI
C:
[23-265]
---------------------------
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
----------
E
S
E
L
T
K
A
R
R
Q
-
I
G
M
I
F
Q
--
H
F
N
L
L
S
S
R
T
V
F
G
N
-
V
-
A
L
P
L
-
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
-
L
S
L
V
G
L
-
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
---
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
----------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
79.68
42%
-116
- C2 -
4YMW
-
?
J:
[6-240]
-------------------------------------
D
V
Y
K
N
F
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
N
N
-
G
----------
K
V
N
I
N
K
V
R
Q
K
-
V
G
M
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
-
L
A
P
V
-
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
-
L
A
K
V
G
L
-
L
D
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
E
---
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
-----
L
S
K
I
-
L
-------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
79.64
42%
-115
- C2 -
4YMS
-
?
J:
[6-240]
-------------------------------------
D
V
Y
K
N
F
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
N
N
-
G
----------
K
V
N
I
N
K
V
R
Q
K
-
V
G
M
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
-
L
A
P
V
-
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
-
L
A
K
V
G
L
-
L
D
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
E
---
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
-----
L
S
K
I
-
L
-------------------------------------------------------------------------------------------------------------------------------------------
124
HHSearch
79.37
37%
-116
- C2 -
1Z47
1
?
A:
[12-250]
------
S
M
T
I
E
F
V
G
V
E
K
I
Y
P
G
G
-----------------------
A
R
S
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
K
R
V
T
D
L
P
----------
P
Q
------
K
R
N
V
G
L
V
F
Q
--
N
Y
A
L
F
Q
H
M
T
V
Y
D
N
-
V
-
S
F
G
L
-
R
E
K
R
V
P
K
D
E
M
D
A
R
V
R
E
L
-
L
R
F
M
R
L
-
E
S
Y
A
N
R
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
E
M
---
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
E
V
Y
E
K
P
G
T
L
F
V
A
S
F
I
G
E
S
N
-------------------------------------------------------------------------------------------------------------------------------------------------
115
Fugue
78.97
28%
-92
- C2 -
1Z47
1
?
A:
[11-355]
-----
G
S
M
T
I
E
F
V
G
V
E
K
I
Y
P
-----------------------
G
G
A
R
S
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
K
R
V
T
D
L
P
----------
P
Q
K
------
R
N
V
G
L
V
F
Q
--
N
Y
A
L
F
Q
H
M
T
V
Y
D
N
-
V
-
S
F
G
L
-
R
E
K
R
V
P
K
D
E
M
D
A
R
V
R
E
L
-
L
R
F
M
R
L
-
E
S
Y
A
N
R
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
E
M
---
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
E
V
Y
E
K
P
G
T
L
F
V
A
S
F
I
G
E
S
N
V
W
T
R
A
V
Q
N
G
R
I
E
V
A
G
A
A
L
P
V
D
P
A
V
S
E
G
S
E
V
A
V
V
V
R
P
K
D
V
E
L
Q
P
A
S
E
R
E
A
----------------------
H
A
Q
V
V
R
S
A
F
K
G
S
Y
S
A
C
W
I
R
T
K
D
G
E
V
W
E
V
H
V
P
S
A
D
R
H
R
------------
W
S
P
G
A
W
V
H
M
N
V
T
R
W
F
I
F
P
R
------
14
PsiBlast_PDB
78.19
37%
-115
- C2 -
2D62
7
?
A:
[12-243]
--------------------------------------
I
W
K
R
F
G
D
V
T
A
V
K
D
L
S
L
E
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
E
E
P
T
R
G
Q
I
Y
I
E
D
N
L
V
A
D
P
E
----------
K
G
V
F
V
P
P
K
E
R
D
V
A
M
V
F
Q
--
S
Y
A
L
Y
P
H
M
T
V
Y
D
N
-
I
-
A
F
P
L
-
K
L
R
K
V
P
K
Q
E
I
D
K
R
V
R
E
V
-
A
E
M
L
G
L
-
T
E
L
L
N
R
K
P
R
E
L
S
G
G
Q
R
Q
R
V
A
L
G
R
A
I
I
R
R
P
K
V
F
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
K
M
R
A
E
L
K
K
L
Q
R
Q
L
---
G
V
T
T
I
Y
V
T
H
D
Q
V
E
A
M
T
M
G
D
R
I
A
V
M
N
K
G
E
L
Q
Q
V
G
T
P
D
E
V
Y
Y
K
P
V
N
T
F
V
A
G
F
I
-----------------------------------------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
77.57
36%
-135
- C2 -
3TUI
1
METN_ECOLI
H:
[23-265]
---------------------------
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
----------
E
S
E
L
T
K
A
R
R
Q
-
I
G
M
I
F
Q
--
H
F
N
L
L
S
S
R
T
V
F
G
N
-
V
-
A
L
P
L
-
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
-
L
S
L
V
G
L
-
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
---
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
----------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
76.88
36%
-125
- C2 -
3TUZ
1
METN_ECOLI
G:
[24-265]
----------------------------
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
----------
E
S
E
L
T
K
A
R
R
Q
-
I
G
M
I
F
Q
--
H
F
N
L
L
S
S
R
T
V
F
G
N
-
V
-
A
L
P
L
-
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
-
L
S
L
V
G
L
-
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
---
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
----------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
76.79
36%
-131
- C2 -
3TUZ
1
METN_ECOLI
H:
[23-265]
---------------------------
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
----------
E
S
E
L
T
K
A
R
R
Q
-
I
G
M
I
F
Q
--
H
F
N
L
L
S
S
R
T
V
F
G
N
-
V
-
A
L
P
L
-
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
-
L
S
L
V
G
L
-
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
---
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
----------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
76.79
33%
-123
- C2 -
4XIG
-
?
S:
[8-265]
------------------------------------
Q
N
V
V
K
R
Y
D
K
T
T
V
V
H
G
V
S
L
D
I
E
P
G
E
F
V
V
L
V
G
P
S
G
C
G
K
S
T
T
L
R
M
V
A
G
L
E
E
I
S
G
G
T
I
R
I
D
G
R
V
I
N
D
L
A
----------
P
------
K
D
R
D
V
A
M
V
F
Q
--
N
Y
A
L
Y
P
H
L
N
V
R
D
N
-
I
-
S
F
G
L
-
R
L
K
R
T
K
K
S
V
I
D
A
A
V
K
T
A
-
A
D
I
L
G
L
-
Q
P
L
L
E
R
K
P
S
D
L
S
G
G
Q
R
Q
R
V
A
M
G
R
A
I
V
R
D
P
K
V
F
L
F
D
Q
P
L
S
N
L
D
A
K
L
R
T
Q
M
R
A
E
I
K
R
L
H
Q
R
L
---
G
T
T
V
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
R
I
V
V
M
R
D
G
L
I
E
Q
I
G
K
P
M
D
L
F
L
H
P
A
N
T
F
V
A
S
F
I
G
S
P
P
M
N
-
L
-
M
P
A
R
I
A
V
D
S
T
Q
H
V
E
L
N
G
G
N
R
I
S
L
---------------------------------------------------------------------------------------------------------------------
123
HHSearch
76.76
36%
-128
* C2 *
4TQU
-
?
S:
[2-238]
------
V
A
S
V
S
I
Q
N
V
V
K
R
Y
D
K
T
------------------------
T
V
V
H
G
V
S
L
D
I
E
P
G
E
F
V
V
L
V
G
P
S
G
C
G
K
S
T
T
L
R
M
V
A
G
L
E
E
I
S
G
G
T
I
R
I
D
G
R
V
I
N
D
L
A
----------
P
K
------
D
R
D
V
A
M
V
F
Q
--
N
Y
A
L
Y
P
H
L
N
V
R
D
N
-
I
-
S
F
G
L
-
R
L
K
R
T
K
K
S
V
I
D
A
A
V
K
T
A
-
A
D
I
L
G
L
-
Q
P
L
L
E
R
K
P
S
D
L
S
G
G
Q
R
Q
R
V
A
M
G
R
A
I
V
R
D
P
K
V
F
L
F
D
Q
P
L
S
N
L
D
A
K
L
R
T
Q
M
R
A
E
I
K
R
L
H
Q
R
L
---
G
T
T
V
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
R
I
V
V
M
R
D
G
L
I
E
Q
I
G
K
P
M
D
L
F
L
H
P
A
N
T
F
V
A
S
F
I
G
S
P
--------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
76.64
36%
-123
- C2 -
3TUI
1
METN_ECOLI
C:
[23-265]
---------------------------
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
----------
E
S
E
L
T
K
A
R
R
Q
-
I
G
M
I
F
Q
--
H
F
N
L
L
S
S
R
T
V
F
G
N
-
V
-
A
L
P
L
-
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
-
L
S
L
V
G
L
-
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
---
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
----------------------------------------------------------------------------------------------------------------------------------------------------
129
HHSearch
76.54
33%
-130
- C2 -
3RLF
3
MALK_ECOLI
A:
[2-237]
-------
A
S
V
Q
L
Q
N
V
T
K
A
W
G
E
V
------------------------
V
V
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
K
R
M
N
D
T
P
----------
P
------
A
E
R
G
V
G
M
V
F
Q
--
S
Y
A
L
Y
P
H
L
S
V
A
E
N
-
M
-
S
F
G
L
-
K
L
A
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
-
A
E
V
L
Q
L
-
A
H
L
L
D
R
K
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
---
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
P
--------------------------------------------------------------------------------------------------------------------------------------------------
89
PsiBlast_CBE
74.81
38%
-131
- C2 -
3FVQ
3
FBPC_NEIG1
B:
[20-239]
------------------------------------------------
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
K
T
I
--
F
S
----------
K
N
T
N
L
P
V
R
E
R
R
L
G
Y
L
V
Q
--
E
G
V
L
F
P
H
L
T
V
Y
R
N
-
I
-
A
Y
G
L
G
N
G
K
G
R
T
A
Q
E
R
Q
R
--
I
E
A
M
L
E
L
T
G
I
-
S
E
L
A
G
R
Y
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
---
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
P
A
D
L
D
A
A
L
F
I
-----------------------------------------------------------------------------------------------------------------------------------------------------
90
PsiBlast_CBE
72.37
38%
-131
- C2 -
3FVQ
3
FBPC_NEIG1
A:
[20-244]
------------------------------------------------
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
K
T
I
--
F
S
----------
K
N
T
N
L
P
V
R
E
R
R
L
G
Y
L
V
Q
--
E
G
V
L
F
P
H
L
T
V
Y
R
N
-
I
-
A
Y
G
L
G
N
G
K
G
R
T
A
Q
E
R
Q
R
--
I
E
A
M
L
E
L
T
G
I
-
S
E
L
A
G
R
Y
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
---
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
P
A
D
L
D
A
A
L
F
I
-----------------------------------------------------------------------------------------------------------------------------------------------------
128
HHSearch
71.76
35%
-122
- C2 -
3FVQ
3
FBPC_NEIG1
A:
[2-248]
------
T
A
A
L
H
I
G
H
L
S
K
S
F
Q
N
T
------------------------
P
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
K
T
I
F
S
K
N
----------
T
N
-
L
-
P
V
R
E
R
R
L
G
Y
L
V
Q
--
E
G
V
L
F
P
H
L
T
V
Y
R
N
-
I
-
A
Y
G
L
-
G
N
G
K
G
R
T
A
Q
E
R
Q
R
I
E
A
M
-
L
E
L
T
G
I
-
S
E
L
A
G
R
Y
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
---
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
P
A
D
L
D
A
A
L
F
I
G
E
G
I
-------------------------------------------------------------------------------------------------------------------------------------------------
91
PsiBlast_CBE
67.55
32%
-113
- C2 -
4MKI
4
ECFA2_CALS4
B:
[5-236]
-------
M
P
I
K
V
E
N
V
S
F
I
Y
N
E
G
T
P
Y
A
-------------------
T
V
A
L
K
D
I
N
F
S
I
D
D
E
E
F
V
G
I
I
G
H
T
G
S
G
K
S
T
L
I
Q
Q
L
N
G
L
L
K
P
S
K
G
K
I
Y
I
N
G
I
D
I
T
D
-
K
----------
K
V
S
L
K
D
I
R
-
K
Q
V
G
L
V
F
Q
YP
E
Y
Q
L
F
-
E
E
T
V
F
K
D
-
I
-
A
F
G
P
-
S
N
L
G
L
S
E
E
E
V
K
E
R
V
Y
E
A
-
M
E
I
V
G
I
S
K
E
L
A
D
K
S
P
F
E
L
S
G
G
Q
K
R
R
V
A
I
A
G
I
L
A
M
R
P
K
I
L
I
L
D
E
P
T
A
G
L
D
P
K
G
K
Q
E
I
L
N
K
I
K
E
I
H
D
K
Y
---
K
M
I
T
I
L
V
S
H
N
M
E
D
I
A
R
I
A
D
K
I
I
V
M
N
R
G
K
I
E
L
I
G
T
P
R
E
V
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
92
PsiBlast_CBE
67.17
32%
-114
- C2 -
4MKI
4
ECFA2_CALS4
A:
[3-236]
-----
R
P
M
P
I
K
V
E
N
V
S
F
I
Y
N
E
G
T
P
Y
A
-------------------
T
V
A
L
K
D
I
N
F
S
I
D
D
E
E
F
V
G
I
I
G
H
T
G
S
G
K
S
T
L
I
Q
Q
L
N
G
L
L
K
P
S
K
G
K
I
Y
I
N
G
I
D
I
T
D
-
K
----------
K
V
S
L
K
D
I
R
-
K
Q
V
G
L
V
F
Q
YP
E
Y
Q
L
F
-
E
E
T
V
F
K
D
-
I
-
A
F
G
P
-
S
N
L
G
L
S
E
E
E
V
K
E
R
V
Y
E
A
-
M
E
I
V
G
I
S
K
E
L
A
D
K
S
P
F
E
L
S
G
G
Q
K
R
R
V
A
I
A
G
I
L
A
M
R
P
K
I
L
I
L
D
E
P
T
A
G
L
D
P
K
G
K
Q
E
I
L
N
K
I
K
E
I
H
D
K
Y
---
K
M
I
T
I
L
V
S
H
N
M
E
D
I
A
R
I
A
D
K
I
I
V
M
N
R
G
K
I
E
L
I
G
T
P
R
E
V
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
93
PsiBlast_CBE
61.00
35%
-106
- C2 -
1B0U
4
HISP_SALTY
A:
[45-254]
-----------------------------------------------------------------------
K
S
T
F
L
R
C
I
N
F
L
E
K
P
S
E
G
A
I
I
V
N
G
Q
N
I
N
L
V
R
D
KDGQLKVAD
K
N
Q
L
R
-
L
L
R
T
R
L
T
M
V
F
Q
--
H
F
N
L
W
S
H
M
T
V
L
E
N
-
V
M
E
A
P
I
-
Q
V
L
G
L
S
K
H
D
A
R
E
R
A
L
K
Y
-
L
A
K
V
G
I
D
E
R
A
Q
G
K
Y
P
V
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
----
E
L
V
G
E
V
L
R
I
M
Q
Q
L
A
E
E
G
K
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
H
Q
G
K
I
E
E
E
G
D
P
E
Q
V
F
G
N
P
Q
S
P
R
L
Q
Q
F
L
K
----------------------------------------------------------------------------------------------------------------------------------------------------