@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu03000: (2016-06-05 )
MLKKIIGIGVSAMLALSLAACGSENDENASAAEQVNKTIIGIDPGSGIMSLTDKAMKDYDLNDWTLISASSAAMTATLKKSYDRKKPIIITGWTPHWMFSRYKLKYLDDPKQSYGSAEEIHTITRKGFSKEQPNAAKLLSQFKWTQDEMGEIMIKVEEGEKPAKVAAEYVNKHKDQIAEWTKGVQKVKGDKINLAYVAWDSEIASTNVIGKVLEDLGYEVTLTQVEAGPMWTAIATGSADASLSAWLPNTHKAYAAKYKGKYDDIGTSMTGVKMGLVVPQYMKNVNSIEDLKK
Atome Classification :
(20 SA)
----------------------------------------------------------------------------------------.........10........20........30...---...------..40......----..50........60.-.-.-......70........80........90........100.----......110--------------.....---...-----------------.120.......130.......140.......150....-.-..160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------------M
L
K
K
I
I
G
I
G
V
S
A
M
L
A
L
S
L
A
ACGSENDEN
A
S
A
A
E
Q
---VN
K
------
T
I
I
G
IDPGS
G
----
I
M
S
L
T
D
K
A
M
KDYD-L-N-
D
-
W
T
L
I
SASS
A
A
M
T
A
T
L
K
KSYDRKK
P
I
I
I
TGWTP
H
W
M
F
S
R
Y
K
----
L
K
YLD
D
P
----------------
K
Q
SYG---
S
A
E
-----------------
E
I
H
T
I
T
R
KGFSKEQP
N
A
A
K
L
L
S
Q
FKW
T
Q
D
EM
G
E
I
M
I
K
V-E-EGE
K
P
A
K
V
A
A
E
Y
V
N
K
H
K
D
Q
I
A
E
W
T
K
G
V
Q
K
VKGDK
I
N
L
A
Y
V
A
WDSEIAS
T
N
V
I
G
K
V
L
E
DLGY
E
V
T
L
T
Q
VEAGP
M
W
T
A
I
ATGSADA
S
L
S
AWLPNT
H
K
A
Y
A
A
KYKGKYDDIGTSMT
G
V
K
M
G
L
V
V
P
Q
Y
M
K
N
V
N
S
I
E
D
LKK
2
PsiBlast_PDB
88.35
100%
-91
- C2 -
2B4M
1
OPUAC_BACSU
A:
[5-268]
---------------------------------------------------------------------------------------------------------------------
S
A
A
E
Q
---
V
N
K
------
T
I
I
G
I
D
P
G
S
G
----
I
M
S
L
T
D
K
A
M
K
D
Y
D
-
L
-
N
-
D
-
W
T
L
I
S
A
S
S
A
A
M
T
A
T
L
K
K
S
Y
D
R
K
K
P
I
I
I
T
G
W
T
P
H
W
M
F
S
R
Y
K
----
L
K
Y
L
D
D
P
----------------
K
Q
S
Y
G
---
S
A
E
-----------------
E
I
H
T
I
T
R
K
G
F
S
K
E
Q
P
N
A
A
K
L
L
S
Q
F
K
W
T
Q
D
E
M
G
E
I
M
I
K
V
-
E
-
E
G
E
K
P
A
K
V
A
A
E
Y
V
N
K
H
K
D
Q
I
A
E
W
T
K
G
V
Q
K
V
K
G
D
K
I
N
L
A
Y
V
A
W
D
S
E
I
A
S
T
N
V
I
G
K
V
L
E
D
L
G
Y
E
V
T
L
T
Q
V
E
A
G
P
M
W
T
A
I
A
T
G
S
A
D
A
S
L
S
A
W
L
P
N
T
H
K
A
Y
A
A
K
Y
K
G
K
Y
D
D
I
G
T
S
M
T
G
V
K
M
G
L
V
V
P
Q
Y
M
K
N
V
N
S
I
E
D
L
K
K
21
PsiBlast_CBE
87.97
100%
-91
- C2 -
2B4M
1
OPUAC_BACSU
B:
[5-268]
---------------------------------------------------------------------------------------------------------------------
S
A
A
E
Q
---
V
N
K
------
T
I
I
G
I
D
P
G
S
G
----
I
M
S
L
T
D
K
A
M
K
D
Y
D
-
L
-
N
-
D
-
W
T
L
I
S
A
S
S
A
A
M
T
A
T
L
K
K
S
Y
D
R
K
K
P
I
I
I
T
G
W
T
P
H
W
M
F
S
R
Y
K
----
L
K
Y
L
D
D
P
----------------
K
Q
S
Y
G
---
S
A
E
-----------------
E
I
H
T
I
T
R
K
G
F
S
K
E
Q
P
N
A
A
K
L
L
S
Q
F
K
W
T
Q
D
E
M
G
E
I
M
I
K
V
-
E
-
E
G
E
K
P
A
K
V
A
A
E
Y
V
N
K
H
K
D
Q
I
A
E
W
T
K
G
V
Q
K
V
K
G
D
K
I
N
L
A
Y
V
A
W
D
S
E
I
A
S
T
N
V
I
G
K
V
L
E
D
L
G
Y
E
V
T
L
T
Q
V
E
A
G
P
M
W
T
A
I
A
T
G
S
A
D
A
S
L
S
A
W
L
P
N
T
H
K
A
Y
A
A
K
Y
K
G
K
Y
D
D
I
G
T
S
M
T
G
V
K
M
G
L
V
V
P
Q
Y
M
K
N
V
N
S
I
E
D
L
K
K
45
Fugue
87.43
100%
-85
- C2 -
2B4L
10
OPUAC_BACSU
A:
[1-268]
-----------------------------------------------------------------------------------------------------------------
D
E
N
A
S
A
A
E
Q
---
V
N
K
------
T
I
I
G
I
D
P
G
S
G
----
I
M
S
L
T
D
K
A
M
K
D
Y
D
-
L
-
N
-
D
-
W
T
L
I
S
A
S
S
A
A
M
T
A
T
L
K
K
S
Y
D
R
K
K
P
I
I
I
T
G
W
T
P
H
W
M
F
S
R
Y
K
----
L
K
Y
L
D
D
P
----------------
K
Q
S
Y
G
---
S
A
E
-----------------
E
I
H
T
I
T
R
K
G
F
S
K
E
Q
P
N
A
A
K
L
L
S
Q
F
K
W
T
Q
D
E
M
G
E
I
M
I
K
V
-
E
-
E
G
E
K
P
A
K
V
A
A
E
Y
V
N
K
H
K
D
Q
I
A
E
W
T
K
G
V
Q
K
V
K
G
D
K
I
N
L
A
Y
V
A
W
D
S
E
I
A
S
T
N
V
I
G
K
V
L
E
D
L
G
Y
E
V
T
L
T
Q
V
E
A
G
P
M
W
T
A
I
A
T
G
S
A
D
A
S
L
S
A
W
L
P
N
T
H
K
A
Y
A
A
K
Y
K
G
K
Y
D
D
I
G
T
S
M
T
G
V
K
M
G
L
V
V
P
Q
Y
M
K
N
V
N
S
I
E
D
L
K
K
1
PsiBlast_PDB
87.43
100%
-85
- C2 -
2B4L
10
OPUAC_BACSU
A:
[1-268]
-----------------------------------------------------------------------------------------------------------------
D
E
N
A
S
A
A
E
Q
---
V
N
K
------
T
I
I
G
I
D
P
G
S
G
----
I
M
S
L
T
D
K
A
M
K
D
Y
D
-
L
-
N
-
D
-
W
T
L
I
S
A
S
S
A
A
M
T
A
T
L
K
K
S
Y
D
R
K
K
P
I
I
I
T
G
W
T
P
H
W
M
F
S
R
Y
K
----
L
K
Y
L
D
D
P
----------------
K
Q
S
Y
G
---
S
A
E
-----------------
E
I
H
T
I
T
R
K
G
F
S
K
E
Q
P
N
A
A
K
L
L
S
Q
F
K
W
T
Q
D
E
M
G
E
I
M
I
K
V
-
E
-
E
G
E
K
P
A
K
V
A
A
E
Y
V
N
K
H
K
D
Q
I
A
E
W
T
K
G
V
Q
K
V
K
G
D
K
I
N
L
A
Y
V
A
W
D
S
E
I
A
S
T
N
V
I
G
K
V
L
E
D
L
G
Y
E
V
T
L
T
Q
V
E
A
G
P
M
W
T
A
I
A
T
G
S
A
D
A
S
L
S
A
W
L
P
N
T
H
K
A
Y
A
A
K
Y
K
G
K
Y
D
D
I
G
T
S
M
T
G
V
K
M
G
L
V
V
P
Q
Y
M
K
N
V
N
S
I
E
D
L
K
K
25
HHSearch
87.09
100%
-86
- C2 -
2B4L
10
OPUAC_BACSU
A:
[4-268]
--------------------------------------------------------------------------------------------------------------------
A
S
A
A
E
Q
---
V
N
K
------
T
I
I
G
I
D
P
G
S
G
----
I
M
S
L
T
D
K
A
M
K
D
Y
D
-
L
-
N
-
D
-
W
T
L
I
S
A
S
S
A
A
M
T
A
T
L
K
K
S
Y
D
R
K
K
P
I
I
I
T
G
W
T
P
H
W
M
F
S
R
Y
K
----
L
K
Y
L
D
D
P
----------------
K
Q
S
Y
G
---
S
A
E
-----------------
E
I
H
T
I
T
R
K
G
F
S
K
E
Q
P
N
A
A
K
L
L
S
Q
F
K
W
T
Q
D
E
M
G
E
I
M
I
K
V
-
E
-
E
G
E
K
P
A
K
V
A
A
E
Y
V
N
K
H
K
D
Q
I
A
E
W
T
K
G
V
Q
K
V
K
G
D
K
I
N
L
A
Y
V
A
W
D
S
E
I
A
S
T
N
V
I
G
K
V
L
E
D
L
G
Y
E
V
T
L
T
Q
V
E
A
G
P
M
W
T
A
I
A
T
G
S
A
D
A
S
L
S
A
W
L
P
N
T
H
K
A
Y
A
A
K
Y
K
G
K
Y
D
D
I
G
T
S
M
T
G
V
K
M
G
L
V
V
P
Q
Y
M
K
N
V
N
S
I
E
D
L
K
K
19
PsiBlast_CBE
85.20
100%
-87
- C2 -
3CHG
1
OPUAC_BACSU
B:
[11-268]
------------------------------------------------------------------------------------------------------------------------------
N
K
------
T
I
I
G
I
D
P
G
S
G
----
I
M
S
L
T
D
K
A
M
K
D
Y
D
-
L
-
N
-
D
-
W
T
L
I
S
A
S
S
A
A
M
T
A
T
L
K
K
S
Y
D
R
K
K
P
I
I
I
T
G
W
T
P
H
W
M
F
S
R
Y
K
----
L
K
Y
L
D
D
P
----------------
K
Q
S
Y
G
---
S
A
E
-----------------
E
I
H
T
I
T
R
K
G
F
S
K
E
Q
P
N
A
A
K
L
L
S
Q
F
K
W
T
Q
D
E
M
G
E
I
M
I
K
V
-
E
-
E
G
E
K
P
A
K
V
A
A
E
Y
V
N
K
H
K
D
Q
I
A
E
W
T
K
G
V
Q
K
V
K
G
D
K
I
N
L
A
Y
V
A
W
D
S
E
I
A
S
T
N
V
I
G
K
V
L
E
D
L
G
Y
E
V
T
L
T
Q
V
E
A
G
P
M
W
T
A
I
A
T
G
S
A
D
A
S
L
S
A
W
L
P
N
T
H
K
A
Y
A
A
K
Y
K
G
K
Y
D
D
I
G
T
S
M
T
G
V
K
M
G
L
V
V
P
Q
Y
M
K
N
V
N
S
I
E
D
L
K
K
20
PsiBlast_CBE
85.18
100%
-90
- C2 -
3CHG
1
OPUAC_BACSU
A:
[11-268]
------------------------------------------------------------------------------------------------------------------------------
N
K
------
T
I
I
G
I
D
P
G
S
G
----
I
M
S
L
T
D
K
A
M
K
D
Y
D
-
L
-
N
-
D
-
W
T
L
I
S
A
S
S
A
A
M
T
A
T
L
K
K
S
Y
D
R
K
K
P
I
I
I
T
G
W
T
P
H
W
M
F
S
R
Y
K
----
L
K
Y
L
D
D
P
----------------
K
Q
S
Y
G
---
S
A
E
-----------------
E
I
H
T
I
T
R
K
G
F
S
K
E
Q
P
N
A
A
K
L
L
S
Q
F
K
W
T
Q
D
E
M
G
E
I
M
I
K
V
-
E
-
E
G
E
K
P
A
K
V
A
A
E
Y
V
N
K
H
K
D
Q
I
A
E
W
T
K
G
V
Q
K
V
K
G
D
K
I
N
L
A
Y
V
A
W
D
S
E
I
A
S
T
N
V
I
G
K
V
L
E
D
L
G
Y
E
V
T
L
T
Q
V
E
A
G
P
M
W
T
A
I
A
T
G
S
A
D
A
S
L
S
A
W
L
P
N
T
H
K
A
Y
A
A
K
Y
K
G
K
Y
D
D
I
G
T
S
M
T
G
V
K
M
G
L
V
V
P
Q
Y
M
K
N
V
N
S
I
E
D
L
K
K
3
PsiBlast_PDB
84.30
100%
-84
- C2 -
3CHG
1
OPUAC_BACSU
D:
[12-268]
-------------------------------------------------------------------------------------------------------------------------------
K
------
T
I
I
G
I
D
P
G
S
G
----
I
M
S
L
T
D
K
A
M
K
D
Y
D
-
L
-
N
-
D
-
W
T
L
I
S
A
S
S
A
A
M
T
A
T
L
K
K
S
Y
D
R
K
K
P
I
I
I
T
G
W
T
P
H
W
M
F
S
R
Y
K
----
L
K
Y
L
D
D
P
----------------
K
Q
S
Y
G
---
S
A
E
-----------------
E
I
H
T
I
T
R
K
G
F
S
K
E
Q
P
N
A
A
K
L
L
S
Q
F
K
W
T
Q
D
E
M
G
E
I
M
I
K
V
-
E
-
E
G
E
K
P
A
K
V
A
A
E
Y
V
N
K
H
K
D
Q
I
A
E
W
T
K
G
V
Q
K
V
K
G
D
K
I
N
L
A
Y
V
A
W
D
S
E
I
A
S
T
N
V
I
G
K
V
L
E
D
L
G
Y
E
V
T
L
T
Q
V
E
A
G
P
M
W
T
A
I
A
T
G
S
A
D
A
S
L
S
A
W
L
P
N
T
H
K
A
Y
A
A
K
Y
K
G
K
Y
D
D
I
G
T
S
M
T
G
V
K
M
G
L
V
V
P
Q
Y
M
K
N
V
N
S
I
E
D
L
K
K
18
PsiBlast_CBE
83.83
100%
-81
- C2 -
3CHG
1
OPUAC_BACSU
C:
[11-268]
------------------------------------------------------------------------------------------------------------------------------
N
K
------
T
I
I
G
I
D
P
G
S
G
----
I
M
S
L
T
D
K
A
M
K
D
Y
D
-
L
-
N
-
D
-
W
T
L
I
S
A
S
S
A
A
M
T
A
T
L
K
K
S
Y
D
R
K
K
P
I
I
I
T
G
W
T
P
H
W
M
F
S
R
Y
K
----
L
K
Y
L
D
D
P
----------------
K
Q
S
Y
G
---
S
A
E
-----------------
E
I
H
T
I
T
R
K
G
F
S
K
E
Q
P
N
A
A
K
L
L
S
Q
F
K
W
T
Q
D
E
M
G
E
I
M
I
K
V
-
E
-
E
G
E
K
P
A
K
V
A
A
E
Y
V
N
K
H
K
D
Q
I
A
E
W
T
K
G
V
Q
K
V
K
G
D
K
I
N
L
A
Y
V
A
W
D
S
E
I
A
S
T
N
V
I
G
K
V
L
E
D
L
G
Y
E
V
T
L
T
Q
V
E
A
G
P
M
W
T
A
I
A
T
G
S
A
D
A
S
L
S
A
W
L
P
N
T
H
K
A
Y
A
A
K
Y
K
G
K
Y
D
D
I
G
T
S
M
T
G
V
K
M
G
L
V
V
P
Q
Y
M
K
N
V
N
S
I
E
D
L
K
K
22
PsiBlast_CBE
56.70
33%
-121
- C2 -
3TMG
2
?
D:
[120-271]
-----------------------------------------------------------------------------------------------------------------------
G
D
K
---
F
K
N
------
K
M
I
G
I
D
A
G
A
G
----
T
Q
I
V
T
E
Q
A
L
N
Y
Y
G
-
L
-
S
K
E
-
Y
E
L
V
P
S
S
E
S
V
M
L
A
S
L
D
S
S
I
K
R
N
E
W
I
L
V
P
L
W
K
P
H
W
A
F
S
R
Y
D
----
I
K
F
L
D
D
P
----------------
D
L
I
M
G
---
G
I
E
-----------------
S
V
H
T
L
V
R
L
G
L
E
N
D
D
F
D
A
Y
Y
V
F
D
H
F
Y
W
S
D
D
L
I
L
P
L
M
D
K
N
-
D
K
E
P
G
K
E
Y
R
N
A
V
E
F
V
E
K
N
K
E
I
V
K
T
W
V
----------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
54.85
33%
-113
- C2 -
3TMG
1
?
C:
[120-271]
-----------------------------------------------------------------------------------------------------------------------
G
D
K
---
F
K
N
------
K
M
I
G
I
D
A
G
A
G
----
T
Q
I
V
T
E
Q
A
L
N
Y
Y
G
-
L
-
S
K
E
-
Y
E
L
V
P
S
S
E
S
V
M
L
A
S
L
D
S
S
I
K
R
N
E
W
I
L
V
P
L
W
K
P
H
W
A
F
S
R
Y
D
----
I
K
F
L
D
D
P
----------------
D
L
I
M
G
---
G
I
E
-----------------
S
V
H
T
L
V
R
L
G
L
E
N
D
D
F
D
A
Y
Y
V
F
D
H
F
Y
W
S
D
D
L
I
L
P
L
M
D
K
N
-
D
K
E
P
G
K
E
Y
R
N
A
V
E
F
V
E
K
N
K
E
I
V
K
T
W
V
----------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
54.05
33%
-107
- C2 -
3TMG
1
?
B:
[120-271]
-----------------------------------------------------------------------------------------------------------------------
G
D
K
---
F
K
N
------
K
M
I
G
I
D
A
G
A
G
----
T
Q
I
V
T
E
Q
A
L
N
Y
Y
G
-
L
-
S
K
E
-
Y
E
L
V
P
S
S
E
S
V
M
L
A
S
L
D
S
S
I
K
R
N
E
W
I
L
V
P
L
W
K
P
H
W
A
F
S
R
Y
D
----
I
K
F
L
D
D
P
----------------
D
L
I
M
G
---
G
I
E
-----------------
S
V
H
T
L
V
R
L
G
L
E
N
D
D
F
D
A
Y
Y
V
F
D
H
F
Y
W
S
D
D
L
I
L
P
L
M
D
K
N
-
D
K
E
P
G
K
E
Y
R
N
A
V
E
F
V
E
K
N
K
E
I
V
K
T
W
V
----------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
52.92
33%
-103
- C2 -
3TMG
2
?
A:
[120-271]
-----------------------------------------------------------------------------------------------------------------------
G
D
K
---
F
K
N
------
K
M
I
G
I
D
A
G
A
G
----
T
Q
I
V
T
E
Q
A
L
N
Y
Y
G
-
L
-
S
K
E
-
Y
E
L
V
P
S
S
E
S
V
M
L
A
S
L
D
S
S
I
K
R
N
E
W
I
L
V
P
L
W
K
P
H
W
A
F
S
R
Y
D
----
I
K
F
L
D
D
P
----------------
D
L
I
M
G
---
G
I
E
-----------------
S
V
H
T
L
V
R
L
G
L
E
N
D
D
F
D
A
Y
Y
V
F
D
H
F
Y
W
S
D
D
L
I
L
P
L
M
D
K
N
-
D
K
E
P
G
K
E
Y
R
N
A
V
E
F
V
E
K
N
K
E
I
V
K
T
W
V
----------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
50.24
45%
-92
- C2 -
3L6H
3
?
A:
[105-254]
-------------------------------------------------------------------------------------------------------------------------
Q
---
A
N
K
------
T
I
T
G
I
E
P
G
A
G
----
V
M
A
A
S
E
K
T
L
N
S
Y
D
N
L
-
K
-
D
-
W
K
L
V
P
S
S
S
G
A
M
T
V
A
L
G
E
A
I
K
Q
H
K
D
I
V
I
T
G
W
S
P
H
W
M
F
N
K
Y
D
----
L
K
Y
L
A
D
P
----------------
K
G
T
M
G
---
T
S
E
-----------------
N
I
N
T
I
V
R
K
G
L
K
K
E
N
P
E
A
Y
K
V
L
D
K
F
N
W
T
T
K
D
M
E
A
V
M
L
D
I
-
Q
-
N
G
K
T
P
E
E
A
A
K
N
W
I
K
D
H
Q
K
E
V
D
K
W
F
K
---------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
49.59
45%
-76
- C2 -
3L6G
1
?
A:
[105-255]
-------------------------------------------------------------------------------------------------------------------------
Q
---
A
N
K
------
T
I
T
G
I
E
P
G
A
G
----
V
M
A
A
S
E
K
T
L
N
S
Y
D
N
L
-
K
-
D
-
W
K
L
V
P
S
S
S
G
A
M
T
V
A
L
G
E
A
I
K
Q
H
K
D
I
V
I
T
G
W
S
P
H
W
M
F
N
K
Y
D
----
L
K
Y
L
A
D
P
----------------
K
G
T
M
G
---
T
S
E
-----------------
N
I
N
T
I
V
R
K
G
L
K
K
E
N
P
E
A
Y
K
V
L
D
K
F
N
W
T
T
K
D
M
E
A
V
M
L
D
I
-
Q
-
N
G
K
T
P
E
E
A
A
K
N
W
I
K
D
H
Q
K
E
V
D
K
W
F
K
G
--------------------------------------------------------------------------------------------------------------
27
HHSearch
49.53
32%
-89
- C2 -
3TMG
2
?
A:
[111-274]
-----------------------------------------------------------------------------------------------------------------
S
S
I
S
E
L
K
G
K
GDK
F
K
N
------
K
M
I
G
I
D
A
G
A
G
----
T
Q
I
V
T
E
Q
A
L
N
Y
Y
G
-
L
-
S
K
E
-
Y
E
L
V
P
S
S
E
S
V
M
L
A
S
L
D
S
S
I
K
R
N
E
W
I
L
V
P
L
W
K
P
H
W
A
F
S
R
Y
D
----
I
K
F
L
D
D
P
----------------
D
L
I
M
G
---
G
I
E
-----------------
S
V
H
T
L
V
R
L
G
L
E
N
D
D
F
D
A
Y
Y
V
F
D
H
F
Y
W
S
D
D
L
I
L
P
L
M
D
K
N
-
D
K
E
P
G
K
E
Y
R
N
A
V
E
F
V
E
K
N
K
E
I
V
K
T
W
V
P
E
K
-------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
49.10
29%
-92
- C2 -
2RIN
1
?
A:
[112-278]
--------------------------------------------------------------------------------------------------------------------
A
A
H
K
D
E
---
L
D
G
------
K
I
Y
G
I
E
P
G
N
D
G
N
R
L
I
I
D
M
V
E
K
G
T
--
F
D
-
L
-
K
-
G
-
F
E
V
V
E
S
S
E
Q
G
M
L
A
Q
V
A
R
A
E
K
S
G
D
P
I
V
F
L
G
W
E
P
H
P
M
N
A
N
F
K
----
L
T
Y
L
S
G
G
----------------
D
D
V
F
G
PNY
G
G
A
-----------------
T
V
H
T
N
V
R
A
G
Y
T
T
E
C
P
N
V
D
K
L
L
Q
N
L
S
F
S
L
Q
M
E
N
E
I
M
G
K
I
L
N
-
D
G
E
D
P
E
K
A
A
A
A
W
L
K
D
N
P
Q
S
I
E
P
W
L
S
G
V
A
T
K
D
G
--------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
48.05
29%
-93
- C2 -
2REG
1
?
A:
[112-278]
--------------------------------------------------------------------------------------------------------------------
A
A
H
K
D
E
---
L
D
G
------
K
I
Y
G
I
E
P
G
N
D
G
N
R
L
I
I
D
M
V
E
K
G
T
--
F
D
-
L
-
K
-
G
-
F
E
V
V
E
S
S
E
Q
G
M
L
A
Q
V
A
R
A
E
K
S
G
D
P
I
V
F
L
G
W
E
P
H
P
M
N
A
N
F
K
----
L
T
Y
L
S
G
G
----------------
D
D
V
F
G
PNY
G
G
A
-----------------
T
V
H
T
N
V
R
A
G
Y
T
T
E
C
P
N
V
D
K
L
L
Q
N
L
S
F
S
L
Q
M
E
N
E
I
M
G
K
I
L
N
-
D
G
E
D
P
E
K
A
A
A
A
W
L
K
D
N
P
Q
S
I
E
P
W
L
S
G
V
A
T
K
D
G
--------------------------------------------------------------------------------------------------------
46
Fugue
47.93
18%
-89
- C2 -
1R9L
2
PROX_ECOLI
A:
[1-309]
ADLPGKG
I
T
V
N
P
V
Q
S
TITEE
T
F
Q
T
L
L
V
S
R
A
L
E
K
L
GYTVNK
P
S
E
V
D
Y
N
V
G
Y
T
S
L
A
S
GDATFTAVNWTPLH
D
N
M
Y
E
A
A
GGDKK
F
Y
R
E
G
VF
V
N
G
A
A
Q
G
Y
L
I
D
K
K
T
A
D
Q
Y
K
I
T
N
I
A
Q
L
K
D
P
K
I
A
K
L
---
F
D
T
NGDG
K
A
D
L
T
G
C
N
P
G
W
G
----
C
E
G
A
I
N
H
Q
L
A
A
Y
E
-
L
-
T
-
N
T
V
T
H
N
Q
G
N
Y
A
A
M
M
A
D
T
I
S
R
Y
K
E
G
K
P
V
F
Y
Y
T
W
T
P
Y
W
V
S
N
E
L
K
PGKD
V
V
W
L
Q
V
P
----------------
F
S
A
L
P
---
G
D
K
NADTKLPNGANYGFPV
S
T
M
H
I
V
A
N
K
A
W
A
E
K
N
P
A
A
A
K
L
F
A
I
M
Q
L
P
V
A
D
I
N
A
Q
N
A
I
M
-
H
-
D
G
K
A
S
E
G
D
I
Q
G
H
V
D
G
W
I
K
A
--------------------------------------------------------------
H
Q
Q
Q
F
D
G
W
V
N
E
A
L
A
A
--------------------------------------
Q
K
12
PsiBlast_PDB
47.13
25%
-142
- C2 -
1R9L
1
PROX_ECOLI
A:
[133-256]
---------------------------------------------------------------------------------------------------------------------------------------
L
T
G
C
N
P
G
W
G
----
C
E
G
A
I
N
H
Q
L
A
A
Y
E
-
L
T
N
-
T
-
V
T
H
N
Q
G
N
Y
A
A
M
M
A
D
T
I
S
R
Y
K
E
G
K
P
V
F
Y
Y
T
W
T
P
Y
W
V
S
N
E
L
K
PGKD
V
V
W
L
Q
V
P
F
S
A
L
P
GDKNADTKLPN
G
A
N
Y
G
F--
P
V
S
-----------------
T
M
H
I
V
A
N
K
A
W
A
E
K
N
P
A
A
A
K
L
F
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------