@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu03170: (2016-06-05 )
MDIKVMEYAAEIARRQSFTKAAEHLHIAQPSLSQQIKKLEAELGLTLFHRSHGSVTLTPHGRRFIEKAEDIIRSRDDLLREMQERSQGIGHKLSIGIPAVTGRYLFPPLLKQFLARYPHVEVQLVEKDPVSLEKMTAKGEVDLSVLSLPIEDERLSITPLLTEPVVLAVPKEKQRWMPPELVALIEKALEEDEGRQPCVPIDMVRNVPFILLKEGFGFRRTVLDLCAESGFKPNAAFKTSHIETAQSLVANGLGVTMAPNMVRRDKDPGVIYLSIQSAPSRTLVFVFLKNRYVSLTAQAFMELSRESLKQTFDEGCLGNKDENI
Atome Classification :
(20 SA)
-.........10........20........30........40........50........60........70..-......80.---.......90....--....100.......110.......120.......-130.......140.......150-.-.......160....-....----170.......180...-....190.......200......-.210....---.--..220.....---..---230.-........240.-.....-.250..-.....--260.---...--.-.-..-270-.-...-.--.-.280...--..-----..290.......300.......310.......320..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-MD
I
K
V
M
E
Y
A
A
E
I
A
R
R
Q
S
F
T
K
A
A
E
H
LHIAQ
P
S
L
S
Q
Q
I
K
K
L
E
A
E
L
G
L
T
L
F
HRSHG
S
V
T
LTPH
G
R
R
F
I
E
K
A
E
D
I
I
R
-
S
R
D
D
L
L
R
E
M
---
Q
E
R
S
QGIG
H
K
L
S
I--GIPAVTGRYL
F
P
P
L
L
K
Q
F
L
A
RYP
H
V
E
V
Q
L
VEKDP-V
S
L
E
K
MTAKG
E
V
D
L
S
V
L
SLPIE--D-ER
L
S
ITPL-LTE
P
V
-
V
L
AV----PKEKQRWM
P
P
E
L
V
A
L
I
-
E
K
A
L
E
EDEGRQPCV
P
I
D
M
VRNV
P
-
F
I
L
LKEGF---G--
F
R
R
T
V
L
D
L
C
A
---ES---G--F-KPNA
A
F
KT
S
H
I
E
-
T
A
Q
S
L
-
V
ANGLG-VTMA
P
--
N
-
M
V---RRD--K-D-P
G
-
V
I
Y
-
L
-
S
IQ-S--A-PS
R
T
L
V
F
--
V
F
-----LKN
R
Y
V
S
L
T
A
Q
A
F
M
E
L
S
R
E
S
L
K
Q
T
F
D
EGCLGNKDENI
39
HHSearch
80.28
26%
-154
* C1 *
4X6G
4
?
A:
[7-303]
-
M
T
L
T
E
L
R
Y
I
V
T
L
A
Q
E
Q
H
F
G
R
A
A
E
R
C
H
V
S
Q
P
T
L
S
V
G
V
K
K
L
E
D
E
L
G
V
L
I
F
E
R
S
K
S
A
V
R
L
T
P
V
G
E
G
I
V
A
Q
A
Q
K
V
L
E
-
Q
A
Q
G
I
R
E
L
A
---
Q
A
G
K
N
Q
L
A
A
P
L
K
V
--
G
A
I
Y
T
I
G
P
Y
L
F
P
H
L
I
P
Q
L
H
R
V
A
P
Q
M
P
L
Y
I
E
E
N
F
T
-
H
I
L
R
D
K
L
R
T
G
E
L
D
A
I
I
I
A
L
P
F
Q
--
E
-
A
D
V
L
T
K
P
L
-
F
D
E
P
F
-
Y
V
L
M
----
P
A
D
H
------
P
W
---------
T
A
----
K
A
S
I
D
S
E
L
L
N
D
K
S
-
L
L
L
L
G
E
G
H
---
D
--
F
R
D
Q
V
L
E
A
C
P
---
T
V
R
K
G
D
--
E
-
N
K
H
T
T
V
E
S
S
S
L
E
-
T
I
R
H
M
-
V
A
S
G
L
G
-
V
S
V
L
P
--
F
-
S
A
---
V
D
S
H
-
H
Y
A
P
G
V
-
I
E
V
-
R
-
P
F
S
-
A
--
P
V
P
F
R
T
V
A
I
--
A
W
-----
R
A
S
F
P
R
P
R
A
I
E
V
L
A
D
S
I
R
L
C
S
----------------
55
Fugue
74.38
22%
-139
- C1 -
1IZ1
-
?
A:
[1-292]
-
M
E
F
R
Q
L
K
Y
F
I
A
V
A
E
A
G
N
M
A
A
A
A
K
R
L
H
V
S
Q
P
P
I
T
R
Q
M
Q
A
L
E
A
D
L
G
V
V
L
L
E
R
S
H
R
G
I
E
L
T
A
A
G
H
A
F
L
E
D
A
R
R
I
L
E
-
L
A
G
R
S
G
D
R
S
---
R
A
A
A
R
G
D
V
G
E
L
S
V
--
A
Y
F
G
T
P
I
Y
R
S
L
P
L
L
L
R
A
F
L
T
S
T
P
T
A
T
V
S
L
T
H
M
T
K
-
D
E
Q
V
E
G
L
L
A
G
T
I
H
V
G
F
S
R
F
F
P
R
--
H
-
P
G
I
E
I
V
N
I
-
A
Q
E
D
L
-
Y
L
A
V
----
H
R
S
Q
S
G
K
-------------------
F
G
K
T
C
K
L
A
D
L
R
A
V
E
-
L
T
L
F
P
R
G
G
---
R
PS
F
A
D
E
V
I
G
L
F
K
---
H
A
---
G
--
I
-
E
P
R
I
A
R
V
V
E
D
A
T
-
A
A
L
A
L
-
T
M
A
G
A
A
-
S
S
I
V
P
--
A
-
S
V
---
A
A
I
--
R
-
W
-
P
D
-
I
A
F
-
A
-
R
I
V
-
G
--
T
-
R
V
K
V
P
I
S
--
C
I
-----
F
R
K
E
K
Q
P
P
I
L
A
R
F
V
E
H
V
R
R
S
A
----------------
1
PsiBlast_PDB
72.63
28%
-135
- C1 -
4X6G
4
?
A:
[7-272]
-
M
T
L
T
E
L
R
Y
I
V
T
L
A
Q
E
Q
H
F
G
R
A
A
E
R
C
H
V
S
Q
P
T
L
S
V
G
V
K
K
L
E
D
E
L
G
V
L
I
F
E
R
S
K
S
A
V
R
L
T
P
V
G
E
G
I
V
A
Q
A
Q
K
V
L
E
-
Q
A
Q
G
I
R
E
L
A
---
Q
A
G
K
N
Q
L
A
A
P
L
K
V
--
G
A
I
Y
T
I
G
P
Y
L
F
P
H
L
I
P
Q
L
H
R
V
A
P
Q
M
P
L
Y
I
E
E
N
F
T
-
H
I
L
R
D
K
L
R
T
G
E
L
D
A
I
I
I
A
L
P
F
Q
--
E
-
A
D
V
L
T
K
P
L
-
F
D
E
P
F
-
Y
V
L
M
----
P
A
D
-
H
P
W
T
---------
A
K
A
S
I
D
S
E
---------
L
L
N
D
K
S
-
L
L
L
L
G
E
G
H
---
D
--
F
R
D
Q
V
L
E
A
C
P
T
V
R
K
G
---
D
--
E
-
N
K
H
T
T
V
E
S
S
S
L
E
-
T
I
R
H
M
-
V
A
S
G
L
G
-
V
S
V
L
P
FS
A
-
V
D
---
S
H
H
--
Y
-
A
-
P
G
-
V
I
E
-
V
-
R
P
F
-
S
--
A
-
P
----------------------------------------------------
2
PsiBlast_PDB
70.40
24%
-120
- C1 -
3K1M
3
BENM_ACIAD
A:
[1-291]
-
M
E
L
R
H
L
R
Y
F
V
A
V
V
E
E
Q
S
F
T
K
A
A
D
K
L
C
I
A
Q
P
P
L
S
R
Q
I
Q
N
L
E
E
E
L
G
I
Q
L
L
E
R
G
S
R
P
V
K
T
T
P
E
G
H
F
F
Y
Q
Y
A
I
K
L
L
S
-
N
V
D
Q
M
V
-
S
M
---
T
K
R
I
A
S
V
E
K
T
I
R
I
--
G
F
V
G
S
L
L
F
G
L
L
P
R
I
I
H
L
Y
R
Q
A
H
P
N
L
R
I
E
L
Y
E
M
G
T
-
K
A
Q
T
E
A
L
K
E
G
R
I
D
A
G
F
G
R
L
K
I
S
--
D
-
P
A
I
K
H
T
L
L
-
R
N
E
R
L
-
M
V
A
V
H
ASH
P
L
N
Q
M
K
D
K
G
V
H
L
N
D
L
I
D
E
K
I
L
L
Y
P
S
S
P
K
P
-----------------------
N
--
F
S
T
H
V
M
N
I
F
S
---
D
H
---
G
--
L
-
E
P
T
K
I
N
E
V
R
E
V
Q
-
L
A
L
G
L
-
V
A
A
G
E
G
-
I
S
L
V
P
--
A
-
S
T
---
Q
S
I
--
Q
-
L
-
F
N
-
L
S
Y
-
V
-
P
L
L
-
D
--
P
-
D
A
I
T
P
I
Y
--
I
A
-----
V
R
N
M
E
E
S
T
Y
I
Y
S
L
Y
E
T
I
R
Q
------------------
3
PsiBlast_PDB
70.38
24%
-119
- C1 -
3K1N
2
BENM_ACIAD
A:
[1-291]
-
M
E
L
R
H
L
R
Y
F
V
A
V
V
E
E
Q
S
F
T
K
A
A
D
K
L
C
I
A
Q
P
P
L
S
R
Q
I
Q
N
L
E
E
E
L
G
I
Q
L
L
E
R
G
S
R
P
V
K
T
T
P
E
G
H
F
F
Y
Q
Y
A
I
K
L
L
S
-
N
V
D
Q
M
V
-
S
M
---
T
K
R
I
A
S
V
E
K
T
I
R
I
--
G
F
V
G
S
L
L
F
G
L
L
P
R
I
I
H
L
Y
R
Q
A
H
P
N
L
R
I
E
L
Y
E
M
G
T
-
K
A
Q
T
E
A
L
K
E
G
R
I
D
A
G
F
G
R
L
K
I
S
--
D
-
P
A
I
K
R
T
L
L
-
R
N
E
R
L
-
M
V
A
V
H
ASH
P
L
N
Q
M
K
D
K
G
V
H
L
N
D
L
I
D
E
K
I
L
L
Y
P
S
S
P
K
P
-----------------------
N
--
F
S
T
H
V
M
N
I
F
S
---
D
H
---
G
--
L
-
E
P
T
K
I
N
E
V
R
E
V
Q
-
L
A
L
G
L
-
V
A
A
G
E
G
-
I
S
L
V
P
--
A
-
S
T
---
Q
S
I
--
Q
-
L
-
F
N
-
L
S
Y
-
V
-
P
L
L
-
D
--
P
-
D
A
I
T
P
I
Y
--
I
A
-----
V
R
N
M
E
E
S
T
Y
I
Y
S
L
Y
E
T
I
R
Q
------------------
57
Fugue
65.28
22%
-136
- C1 -
3FZV
1
?
A:
[4-300]
-
Y
T
L
R
Q
L
K
Y
F
V
T
T
V
E
C
G
S
V
A
E
A
S
R
K
L
Y
I
-
A
Q
S
I
S
T
A
V
K
G
L
E
E
S
F
V
---------
Q
L
F
L
T
P
A
G
A
R
F
Y
R
K
A
Q
E
L
L
R
M
A
H
E
F
E
Q
N
L
A
---
D
N
D
V
I
A
--
G
Q
I
D
I
--
G
C
F
E
T
V
A
P
L
Y
L
P
G
L
I
A
G
F
R
Q
A
Y
P
G
V
E
I
R
I
R
D
G
E
Q
-
Q
E
L
V
Q
G
L
T
S
G
R
F
D
L
A
F
L
Y
E
H
D
L
--
D
-
S
T
I
E
T
E
P
L
M
P
P
Q
R
P
-
H
A
L
L
----
P
E
G
-------------------
H
R
F
A
G
Q
A
Q
V
S
L
R
D
L
C
L
E
P
M
I
L
L
D
V
Q
P
-------
S
R
T
Y
F
V
S
L
F
E
---
E
L
---
G
--
L
-
T
P
N
I
A
F
S
S
P
S
I
E
M
V
--
R
G
M
V
G
Q
G
F
G
-
F
S
L
L
V
--
T
-
R
P
---
H
S
E
CT
Y
-
D
-
G
K
-
K
V
V
M
V
-
D
L
A
E
P
--
V
-
S
T
S
G
L
A
A
--
A
W
-----
L
K
R
A
Q
L
T
K
P
A
R
L
F
V
D
Y
C
R
E
Q
L
G
K
--------------
4
PsiBlast_PDB
64.95
24%
-107
- C- -
3K1P
-
BENM_ACIAD
A:
[1-291]
-
M
E
L
R
H
L
R
Y
F
V
A
V
V
E
E
Q
S
F
T
K
A
A
D
K
L
C
I
A
Q
P
P
L
S
R
Q
I
Q
N
L
E
E
E
L
G
I
Q
L
L
E
R
G
S
R
P
V
K
T
T
P
E
G
H
F
F
Y
Q
Y
A
I
K
L
L
S
-
N
V
D
Q
M
V
-
S
M
---
T
K
R
I
A
S
V
E
K
T
I
R
I
--
G
F
V
G
S
L
L
F
G
L
L
P
R
I
I
H
L
Y
R
Q
A
H
P
N
L
R
I
E
L
Y
E
M
G
T
-
K
A
Q
T
E
A
L
K
E
G
R
I
D
A
G
F
G
R
L
K
I
S
--
D
-
P
A
I
K
R
T
L
L
-
R
N
E
R
L
-
M
V
A
V
H
ASH
P
L
N
Q
M
K
D
K
G
V
H
L
N
D
L
I
D
E
K
I
L
L
Y
P
S
S
P
K
P
-----------------------
N
--
F
S
T
H
V
M
N
I
F
S
---
D
H
---
G
--
L
-
E
P
T
K
I
N
E
V
R
K
V
Q
-
L
A
L
G
L
-
V
A
A
G
E
G
-
I
S
L
V
P
--
A
-
S
T
---
Q
S
I
--
Q
-
L
-
F
N
-
L
S
Y
-
V
-
P
L
L
-
D
--
P
-
D
A
I
T
P
I
Y
--
I
A
-----
V
R
N
M
E
E
S
T
Y
I
Y
S
L
Y
E
T
I
R
Q
------------------
17
PsiBlast_PDB
63.57
25%
-127
- C1 -
3HHG
-
?
A:
[13-294]
-----------
Q
V
V
E
S
G
S
F
S
R
A
A
E
Q
L
A
M
A
N
S
A
V
S
R
I
V
K
R
L
E
E
K
L
G
V
N
L
L
N
R
T
T
R
Q
L
S
L
T
E
E
G
A
Q
Y
F
R
R
A
Q
R
I
L
Q
-
E
M
A
A
A
E
T
E
M
L
A
V
H
E
I
P
Q
G
V
---
L
S
V
D
S
A
M
P
M
V
L
--
H
L
L
A
P
L
A
A
K
F
N
E
R
Y
P
H
I
R
L
S
L
V
S
S
E
G
Y
I
N
L
----
I
E
R
K
V
D
I
A
L
R
A
G
E
L
D
--
D
-
S
G
L
R
A
R
H
L
-
F
D
S
R
F
R
V
I
A
S
----
P
E
Y
L
A
K
H
G
T
P
Q
--------
S
T
E
E
L
A
G
H
Q
-
C
L
----------------
G
F
TEP
G
--
S
L
N
T
W
A
V
L
D
A
---
Q
G
---
N
P-
Y
-
K
I
S
P
H
F
T
A
S
S
G
E
-
I
L
R
S
L
-
C
L
S
G
C
G
I
V
C
L
S
D
--
F
-
L
V
---
D
N
D
--
I
-
A
-
E
G
K
L
I
P
-
L
-
L
A
E
-
Q
--
T
-
S
D
K
T
H
P
F
N
A
V
Y
-----
Y
S
D
K
A
V
N
L
R
L
R
V
F
L
D
F
L
V
E
E
L
G
---------------
36
HHSearch
62.24
19%
-147
- C1 -
3FXQ
7
TSAR_COMTE
A:
[2-296]
-
L
K
L
Q
T
L
Q
A
L
I
C
I
E
E
V
G
S
L
R
A
A
A
Q
L
L
H
L
S
Q
P
A
L
S
A
A
I
Q
Q
L
E
D
E
L
K
A
P
L
L
V
R
T
K
R
G
V
S
L
T
S
F
G
Q
A
F
M
K
H
A
R
L
I
V
T
-
E
S
R
R
A
Q
E
E
I
---
G
Q
L
R
G
R
W
E
G
H
I
T
F
--
A
A
S
P
A
I
A
L
A
A
L
P
L
A
L
A
S
F
A
R
E
F
P
D
V
T
V
N
V
R
D
G
M
Y
-
P
A
V
S
P
Q
L
R
D
G
T
L
D
F
A
L
T
A
A
H
K
H
DI
D
-
T
D
L
E
A
Q
P
L
-
Y
V
S
D
V
-
V
I
V
G
----
Q
R
Q
H
------
P
M
---------
A
N
------
A
T
R
L
A
E
L
Q
E
C
R
-
W
A
F
S
S
A
P
R
---
G
--
P
G
A
I
I
R
N
A
F
A
---
R
Y
---
G
--
L
P
E
P
K
L
G
L
V
C
E
S
F
L
-
A
L
P
G
V
-
V
A
H
S
D
L
-
L
T
T
M
P
--
R
-
T
L
---
Y
E
R
N-
A
-
F
K
D
Q
-
L
C
S
-
I
-
P
L
Q
-
D
--
A
L
P
N
P
T
I
Y
V
--
L
R
-----
R
H
D
L
P
V
T
P
A
A
A
G
L
I
R
W
I
Q
H
H
A
L
---------------
43
HHSearch
61.07
20%
-130
- C1 -
3HHG
-
?
A:
[3-294]
-
T
N
S
E
E
L
T
V
F
V
Q
V
V
E
S
G
S
F
S
R
A
A
E
Q
L
A
M
A
N
S
A
V
S
R
I
V
K
R
L
E
E
K
L
G
V
N
L
L
N
R
T
T
R
Q
L
S
L
T
E
E
G
A
Q
Y
F
R
R
A
Q
R
I
L
Q
-
E
M
A
A
A
E
T
E
M
---
L
A
V
H
E
I
P
Q
G
V
L
S
V
--
D
S
A
M
P
M
V
L
H
L
L
A
P
L
A
A
K
F
N
E
R
Y
P
H
I
R
L
S
L
V
S
S
E
----
G
Y
I
N
L
I
E
R
K
V
D
I
A
L
R
A
G
E
L
D
--
D
-
S
G
L
R
A
R
H
L
-
F
D
S
R
F
-
R
V
I
A
----
S
P
E
Y
------
L
A
---------
K
H
----
G
T
P
Q
S
T
E
E
L
A
G
H
Q
-
C
L
G
F
T
E
P
G
---
S
--
L
N
T
W
--
A
V
L
D
---
A
Q
---
G
NP
Y
-
K
I
S
P
H
F
T
A
S
S
G
E
-
I
L
R
S
L
-
C
L
S
G
C
G
-
I
V
C
L
S
--
D
-
F
L
---
V
D
N
D
-
I
-
A
E
G
K
-
L
I
P
-
L
-
L
A
E
-
Q
TS
D
-
K
T
H
P
F
N
A
--
V
Y
-----
Y
S
D
K
A
V
N
L
R
L
R
V
F
L
D
F
L
V
E
E
L
G
---------------
44
HHSearch
60.54
15%
-131
- C1 -
3SZP
-
?
A:
[1-289]
-
M
K
L
D
D
L
N
L
F
R
L
V
V
E
N
G
S
Y
T
S
T
S
K
K
T
M
I
P
V
A
T
I
T
R
R
I
Q
A
L
E
D
S
L
N
L
R
L
L
N
R
H
A
R
K
L
T
L
T
E
A
G
E
R
F
Y
K
D
C
S
P
L
L
E
-
R
L
A
S
M
T
E
E
I
---
T
D
E
C
R
G
A
S
G
R
I
R
I
--
S
A
P
S
N
L
T
K
R
M
M
M
P
M
F
N
A
F
M
E
K
Y
P
D
I
H
I
E
L
M
M
S
N
Q
----
A
D
D
L
D
P
T
E
W
D
V
I
F
R
V
G
P
Q
R
--
D
-
S
S
L
I
A
R
K
I
-
G
E
V
K
D
-
I
L
V
A
----
S
P
Q
Y
------
L
S
---------
S
H
----
P
Q
P
T
H
A
E
E
L
H
Q
H
Q
-
L
L
K
G
Y
P
L
L
---
K
--
W
-
Q
L
T
N
S
Q
G
E
---
T
V
---
V
--
N
-
S
D
R
G
R
F
Q
A
S
A
L
N
-
V
V
R
S
A
-
C
S
E
G
L
G
-
I
T
L
M
P
--
D
-
V
M
---
L
R
E
F
-
L
-
E
D
G
S
-
L
V
Q
-
V
-
L
S
D
-
W
--
S
S
N
P
R
D
I
Y
M
--
L
Y
-----
N
H
K
D
H
Q
P
E
K
V
R
L
F
I
D
F
V
I
G
Y
H
----------------
48
HHSearch
59.38
25%
-153
- C1 -
1I6A
-
OXYR_ECOLI
A:
[89-298]
---------------------------------------------------------------------------------------------
M
S
G
P
L
H
I
--
G
L
I
P
T
V
G
P
Y
L
L
P
H
I
I
P
M
L
H
Q
T
F
P
K
L
E
M
Y
L
H
E
A
Q
T
-
H
Q
L
L
A
Q
L
D
S
G
K
L
D
A
V
I
L
A
L
V
K
E
--
S
-
E
A
F
I
E
V
P
L
-
F
D
E
P
M
-
L
L
A
I
----
Y
E
D
H
------
P
W
---------
A
N
----
R
E
A
V
P
M
A
D
L
A
G
E
K
-
L
L
M
L
E
D
G
H
---
C
--
L
R
D
Q
A
M
G
F
C
F
---
E
A
---
G
--
A
-
D
E
D
T
H
F
R
A
T
S
L
E
-
T
L
R
N
M
-
V
A
A
G
S
G
-
I
T
L
L
P
--
A
-
L
A
---
V
P
P
E-
R
-
K
R
D
G
-
V
V
Y
-
L
-
P
A
I
-
K
--
P
E
P
R
R
T
I
G
L
--
V
Y
-----
R
P
G
S
P
L
R
S
R
Y
E
Q
L
A
E
A
I
R
A
R
M
D
G
H
F
D
-----------
56
Fugue
59.24
25%
-147
- C1 -
1I6A
-
OXYR_ECOLI
A:
[87-298]
-------------------------------------------------------------------------------------------
E
T
M
S
G
P
L
H
I
--
G
L
I
P
T
V
G
P
Y
L
L
P
H
I
I
P
M
L
H
Q
T
F
P
K
L
E
M
Y
L
H
E
A
Q
T
-
H
Q
L
L
A
Q
L
D
S
G
K
L
D
A
V
I
L
A
L
V
K
E
--
S
-
E
A
F
I
E
V
P
L
-
F
D
E
P
M
-
L
L
A
I
----
Y
E
D
-------------------
H
P
W
A
N
R
E
A
V
P
M
A
D
L
A
G
E
K
-
L
L
M
L
E
D
G
H
---
C
--
L
R
D
Q
A
M
G
F
C
F
---
E
A
---
G
--
A
-
D
E
D
T
H
F
R
A
T
S
L
E
-
T
L
R
N
M
-
V
A
A
G
S
G
-
I
T
L
L
P
--
A
-
L
A
---
V
P
P
ER
K
-
R
-
D
G
-
V
V
Y
-
L
-
P
A
I
K
P
--
E
-
P
R
R
T
I
G
L
--
V
Y
-----
R
P
G
S
P
L
R
S
R
Y
E
Q
L
A
E
A
I
R
A
R
M
D
G
H
F
D
-----------
58
Fugue
59.06
24%
-150
- C1 -
1I6A
-
OXYR_ECOLI
A:
[87-298]
------------------------------------------------------------------------------------------
E
-
T
M
S
G
P
L
H
I
--
G
L
I
P
T
V
G
P
Y
L
L
P
H
I
I
P
M
L
H
Q
T
F
P
K
L
E
M
Y
L
H
E
A
Q
T
-
H
Q
L
L
A
Q
L
D
S
G
K
L
D
A
V
I
L
A
L
V
-
K
--
E
S
E
A
F
I
E
V
P
L
-
F
D
E
P
M
-
L
L
A
I
----
Y
E
D
-------------------
H
P
W
A
N
R
E
A
V
P
M
A
D
L
A
G
E
K
-
L
L
M
L
E
D
G
H
---
C
--
L
R
D
Q
A
M
G
F
C
F
---
E
A
---
G
--
A
-
D
E
D
T
H
F
R
A
T
S
L
E
-
T
L
R
N
M
-
V
A
A
G
S
G
-
I
T
L
L
P
--
A
-
L
A
VP-
P
E
R
--
K
-
R
-
D
G
-
V
V
Y
-
L
-
P
A
I
K
P
--
E
-
P
R
R
T
I
G
L
--
V
Y
-----
R
P
G
S
P
L
R
S
R
Y
E
Q
L
A
E
A
I
R
A
R
M
D
-
G
H
F
D
----------
11
PsiBlast_PDB
56.88
27%
-146
- C1 -
1I6A
-
OXYR_ECOLI
A:
[93-298]
-------------------------------------------------------------------------------------------------
L
H
I
--
G
L
I
P
T
V
G
P
Y
L
L
P
H
I
I
P
M
L
H
Q
T
F
P
K
L
E
M
Y
L
H
E
A
Q
T
-
H
Q
L
L
A
Q
L
D
S
G
K
L
D
A
V
I
L
A
L
V
K
E
--
S
-
E
A
F
I
E
V
P
L
-
F
D
E
P
M
-
L
L
A
I
-----
Y
E
D
H
P
W
A
N
R
E
A
V
P
M
A
-
D
L
A
G
E
K
------------------
L
L
M
L
E
D
G
H
---
C
--
L
R
D
Q
A
M
G
F
C
F
---
E
A
---
G
--
A
-
D
E
D
T
H
F
R
A
T
S
L
E
-
T
L
R
N
M
-
V
A
A
G
S
G
-
I
T
L
L
P
--
A
-
L
A
VPP
E
R
K
--
R
-
D
--
G
-
V
V
Y
-
L
P
A
I
K
-
P
--
E
-
P
R
R
T
I
G
L
--
V
Y
R
P
GSP
L
R
S
R
Y
E
Q
L
A
-----
E
A
I
R
A
R
M
D
G
H
F
D
-----------
47
HHSearch
56.80
22%
-156
- C1 -
2HXR
-
CYNR_ECOLI
A:
[92-291]
------------------------------------------------------------------------------------------------
S
L
R
I
--
A
V
T
P
T
F
T
S
Y
F
I
G
P
L
M
A
D
F
Y
A
R
Y
P
S
I
T
L
Q
L
Q
E
M
S
Q
-
E
K
I
E
D
M
L
C
R
D
E
L
D
V
G
I
A
F
A
P
V
H
--
S
-
P
E
L
E
A
I
P
L
-
L
T
E
S
L
-
A
L
V
V
----
A
Q
H
H
------
P
L
---------
A
V
----
H
E
Q
V
A
L
S
R
L
H
D
E
K
-
L
V
L
L
S
A
E
F
---
A
--
T
R
E
Q
I
D
H
Y
C
E
---
K
A
---
G
--
L
-
H
P
Q
V
V
I
E
A
N
S
I
S
-
A
V
L
E
L
-
I
R
R
T
S
L
-
S
T
L
L
P
--
A
-
A
I
---
A
T
Q
--
H
---
D
G
-
L
K
A
-
I
-
S
L
A
-
P
--
P
L
L
E
R
T
A
V
L
--
L
R
-----
R
K
N
S
W
Q
T
A
A
A
K
A
F
L
H
M
A
L
D
K
C
A
---------------
60
Fugue
56.13
17%
-110
- C1 -
3ISP
-
Y1985_MYCTU
A:
[5-296]
Q
L
D
G
P
Q
L
A
A
L
A
A
V
V
E
L
G
S
F
D
A
A
A
E
R
L
H
V
T
P
S
A
V
S
Q
R
I
K
S
L
E
Q
Q
V
G
Q
V
L
V
V
R
E
-
K
P
C
R
A
T
T
A
G
I
P
L
L
R
L
A
A
Q
T
A
L
-
L
E
S
E
A
L
A
E
M
---
G
A
S
L
K
R
--
T
R
I
T
I
--
A
V
N
A
D
S
M
A
T
W
F
S
A
V
F
D
G
L
----
G
D
V
L
L
D
V
R
I
E
D
Q
-
D
H
S
A
R
L
L
R
E
G
V
A
M
G
A
V
T
T
E
R
N
P
--
V
-
P
G
C
R
V
H
P
L
G
E
M
R
Y
L
-
P
V
A
S
----
R
P
F
V
Q
R
H
L
S
D
G
-------------------
F
T
A
A
A
A
A
K
A
P
-
S
L
A
W
N
R
D
D
---
G
--
L
Q
D
M
L
V
R
K
A
F
---
R
R
---
A
--
I
-
T
R
P
T
H
F
V
P
T
-
T
E
-
G
F
T
A
A
-
A
R
A
G
L
G
-
W
G
M
F
P
--
E
K
L
A
---
A
S
P
--
L
-
A
-
D
G
-
S
F
V
-
R
-
V
C
D
-
I
--
H
-
L
D
V
P
L
Y
W
--
Q
C
-----
W
K
L
D
--
S
P
I
I
A
R
I
T
D
T
V
R
A
A
A
S
G
L
Y
R
G
Q
---------
40
HHSearch
55.97
22%
-149
- C1 -
1AL3
1
CYSB_KLEPN
A:
[88-298]
------------------------------------------------------------------------------------------
T
W
P
D
K
G
S
L
Y
V
--
A
T
T
H
T
Q
A
R
Y
A
L
P
G
V
I
K
G
F
I
E
R
Y
P
R
V
S
L
H
M
H
Q
G
S
P
-
T
Q
I
A
E
A
V
S
K
G
N
A
D
F
A
I
A
T
E
A
L
H
L-
Y
-
D
D
L
V
M
L
P
C
-
Y
H
W
N
R
-
S
I
V
V
----
T
P
E
H
------
P
L
---------
A
T
----
K
G
S
V
S
I
E
E
L
A
Q
Y
P
-
L
V
T
Y
T
F
G
F
---
T
--
G
R
S
E
L
D
T
A
F
N
---
R
A
---
G
--
L
-
T
P
R
I
V
F
T
A
T
D
A
D
-
V
I
K
T
Y
-
V
R
L
G
L
G
-
V
G
V
I
A
--
S
-
M
A
---
V
D
P
--
V
-
S
D
P
D
-
L
V
K
-
L
-
D
A
N
-
G
--
I
F
S
H
S
T
T
K
I
--
G
F
-----
R
R
S
T
F
L
R
S
Y
M
Y
D
F
I
Q
R
F
A
P
H
L
T
R
D
-------------
9
PsiBlast_PDB
55.97
27%
-158
- C1 -
1I69
1
OXYR_ECOLI
A:
[7-212]
-------------------------------------------------------------------------------------------------
L
H
I
--
G
L
I
P
T
V
G
P
Y
L
L
P
H
I
I
P
M
L
H
Q
T
F
P
K
L
E
M
Y
L
H
E
A
Q
T
-
H
Q
L
L
A
Q
L
D
S
G
K
L
D
A
V
I
L
A
L
V
K
E
--
S
-
E
A
F
I
E
V
P
L
-
F
D
E
P
M
-
L
L
A
I
-----
Y
E
D
H
P
W
A
N
R
E
A
V
P
M
A
-
D
L
A
G
E
K
------------------
L
L
M
L
E
D
G
H
---
S
--
L
R
D
Q
A
M
G
F
C
F
---------------
D
T
H
F
R
A
T
S
L
E
-
T
L
R
N
M
-
V
A
A
G
S
G
-
I
T
L
L
P
--
A
-
L
A
VPP
E
R
K
--
R
-
D
--
G
-
V
V
Y
-
L
P
A
I
K
-
P
--
E
-
P
R
R
T
I
G
L
--
V
Y
R
PGSP
L
R
S
R
Y
E
Q
L
A
-----
E
A
I
R
A
R
M
D
G
H
F
D
-----------
42
HHSearch
55.83
25%
-149
- C1 -
2H98
2
CATM_ACIAD
A:
[89-296]
----------------------------------------------------------------------------------------------
S
Q
T
L
R
I
--
G
Y
V
S
S
L
L
Y
G
L
L
P
E
I
I
Y
L
F
R
Q
Q
N
P
E
I
H
I
E
L
I
E
C
G
T
-
K
D
Q
I
N
A
L
K
Q
G
K
I
D
L
G
F
G
R
L
K
I
T
--
D
-
P
A
I
R
R
I
M
L
-
H
K
E
Q
L
-
K
L
A
I
----
H
K
H
H
------
H
L
---------
N
Q
F
--
A
A
T
G
V
H
L
S
Q
I
I
D
E
P
-
M
L
L
Y
P
V
S
Q
KP-
N
--
F
A
T
F
I
Q
S
L
F
T
---
E
L
---
G
--
L
-
V
P
S
K
L
T
E
I
R
E
I
Q
-
L
A
L
G
L
-
V
A
A
G
E
G
-
V
C
I
V
P
--
A
-
S
A
---
M
D
I
--
G
-
V
-
K
N
-
L
L
Y
-
I
-
P
I
L
-
D
--
D
D
A
Y
S
P
I
S
L
--
A
V
-----
R
N
M
D
-
H
S
N
Y
I
P
K
I
L
A
C
V
Q
E
V
F
A
T
H
-------------