@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu03190: (2016-06-05 )
MKQRIIDELKRIEQSYGVKIVYAVESGSRAWGFPSQDSDYDVRFIYVPKKEWYFSIEQERDVIEEPIHDLLDISGWELRKTLRLFKKSNPPLLEWLSSDIVYYEAFTTAEQLRKLRTEAFKPEASVYHYINMARRNVKDYLQGQEVKIKKYFYVLRPILACQWIEKHGTIPPMDFTVLMNELVAEPELKAEMETLLERKRRGEELDLEARIDVIHQFIETEIERIMEAAKELKAEKKDMTSELNRLLLNTVEEVWKDGGS
Atome Classification :
(20 SA)
--------------.........10.......-----.20........-.30......-------------.--.40------........------.-------50.....--...60.----......---------.70.........80........------90........100.......--.110......-.120..------...----..130.......140-----.......-----150....-----------...----160-----........170.......180----.......190......----.200...-------.-----------...210...----------------------------------..-..220...-....230....----------....240....-...250.......260---------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------M
K
Q
R
I
I
D
E
L
K
R
I
E
Q
SYG
V
-----
K
I
-
V
Y
A
VESGS-RAWGFPSQD-------------S--DY-------
D
V
R
F
I
Y
VP------
K
-------
K
E
W
Y
F
S
I
--
E
Q
E
R
D
V
----
I
E
E
P
I
H
---------
D
L
-LDIS
G
W
E
L
R
K
T
L
R
L
F
KKSN------
P
P
L
L
E
W
L
SSD
I
V
-
Y
Y
EAF
T
T
--
A
E
Q
L
R
K
L
R
T
E
-AFKPE
A
------
S
V
Y
----
H
Y
I
N
M
A
R
R
N
V
K
D
Y
LQ-----GQE
V
K
I
K
-----
K
Y
F
Y
V
L
R
-----------
P
I
L
----
A
C
------
Q
W
I
E
K
HGTIPP
M
D
F
T
V
L
M
N
E
L----VAE
P
E
L
K
A
E
M
E
T
L
L
E
R
----
K
RRGEEL-------
D
-----------
L
E
A
R
I
D
V
I
H
----------------------------------
Q
F
-
I
E
T
E
I
E
R
I
-
M
E
A
A
K
E
-
L
K
A
E
----------
K
K
D
M
T
S
E
L
N
R
L
-
L
L
N
T
V
E
E
V
W
KDGGS-----------------------------------
46
Fugue
57.11
9%
-89
- C6 -
3JZ0
6
?
A:
[22-287]
--------------
L
K
Q
K
E
L
I
A
N
V
K
N
L
T
E
S
D
E
-----
R
I
-
T
A
C
M
M
Y
G
S
-
F
T
K
G
E
G
D
Q
Y
-------------
S
--
D
I
-------
E
F
Y
I
F
L
K
H
------
S
ITSNFD
S
S
N
W
L
F
D
V
--
A
P
Y
L
M
L
----
Y
K
N
E
Y
G
TE
V
V
I
F
DNL
I
R
-
G
E
F
H
F
L
S
E
K
D
M
N
I
I
P
S
F
K
D
SGYIPD
T
K
A
M
L
I
Y
D
E
T
G
Q
-
L
E
N
Y
L
S
E
--
I
S
G
A
R
P
N
R
L
T
-
E
E
N
A
N
F
------
L
L
C
----
N
F
S
N
L
W
L
M
G
I
N
V
L
K
R
-----
G
E
Y
A
R
S
L
-----
E
L
L
S
Q
L
Q
-----------
K
N
T
----
L
Q
------
L
I
R
M
A
E
K
N
A
D
N
W
----------------
L
N
M
S
K
N
L
E
K
E
I
S
L
----
E
N
Y
K
K
F
A
-------
K
-----------
T
T
A
R
L
D
--
K
----------------------------------
V
E
-
L
F
E
A
Y
K
N
S
-
L
L
L
V
M
D
-
L
Q
S
H
L
---------
I
E
Q
Y
N
L
K
V
T
H
D
-
I
L
E
R
L
L
N
Y
I
S
E
--------------------------------------
40
Fugue
55.09
11%
-66
* C6 *
4EBJ
8
?
A:
[15-272]
--------E
N
L
Y
F
Q
G
V
Q
H
T
I
A
R
W
V
D
R
L
R
E
E
Y
A
-----
D
A
-
V
A
I
L
L
K
G
S
-
Y
A
R
G
D
A
A
T
W
-------------
S
--
D
I
-------
D
F
D
V
L
V
S
T
------
Q
-------
D
V
E
D
Y
R
T
--
W
I
E
P
V
-----
G
D
R
L
V
H
---------
I
S
-
A
A
V
E
W
V
T
G
W
E
R
D
T
V
D
P
S
S
W
------
S
Y
G
L
P
T
Q
E
T
T
R
L
M
W
A
I
N
D
E
T
--
R
R
R
L
D
R
P
Y
K
T
-
H
P
A
A
E
P
------
E
V
E
----
D
T
V
E
A
L
G
K
I
R
N
A
I
A
R
-----
G
D
D
L
G
V
Y
-----
Q
S
A
Q
T
V
A
-----------
K
L
V
----
P
T
------
L
L
I
P
I
N
P
P
V
T
V
S
H
A
R
Q
A
I
E
A
I
----
L
A
F
P
R
V
P
V
G
F
A
A
D
W
L
T
----
C
L
G
L
V
E
E
-------
R
-----------
S
A
R
S
T
A
A
A
A
----------------------------------
E
R
M
V
---------
R
G
V
L
E
M
L
P
T
D
----------
P
D
L
L
G
E
D
I
A
R
L
M
N
A
G
L
L
E
K
Y
V
Q
Q
--------------------------------------
41
Fugue
54.43
15%
-78
- C3 -
2O4U
9
DHDH_MACFA
X:
[2-332]
---ALRWGIVSVGL
I
S
S
D
F
T
A
V
L
Q
T
L
P
R
S
E
H
Q
-----
V
V
-
A
V
A
A
R
D
L
S
-
R
A
K
E
F
A
Q
K
H
DIPKAYGSYEELA
K
--
D
P
-------
N
V
E
V
A
Y
V
G
TQHPQH
K
-------
A
A
V
M
L
C
L
--
A
A
G
K
A
V
----
L
C
E
K
P
-------------
M
G
V
N
A
A
E
V
R
E
M
V
T
E
A
R
S
R
G
------
L
F
L
M
E
A
I
------
W
T
R
F
F
P
A
--
S
E
A
L
R
S
V
L
A
Q
G
T
L
G
D
L
R
------
V
A
R
----
A
E
F
G
K
N
L
T
H
V
P
R
A
V
D
WAQAG
G
A
L
L
D
L
G
-----
I
Y
C
V
Q
F
I
-----------
S
M
V
FGGQ
K
P
------
E
K
I
S
V
M
G
R
R
H
E
T
G
V
D
D
T
V
T
V
L
----
L
Q
Y
P
G
E
V
H
G
S
F
T
C
S
I
T
----
A
Q
L
S
N
T
A
-------
S
-----------
V
S
G
T
K
G
M
A
Q
LLNPCWCPTELVVKGEHKEFLLPPVPKNCNFDNG
A
G
-
M
S
Y
E
A
K
H
V
-
R
E
C
L
R
K
-
G
L
K
E
----------
S
P
V
I
P
L
V
E
S
E
L
-
L
A
D
I
L
E
E
V
R
R
A
I
G
V
TFPQD------------------------------
43
Fugue
53.04
16%
-61
- C4 -
3OPY
2
PFKA3_PICPA
I:
[5-351]
DSIIRDLERENVGP
E
F
G
E
F
L
N
T
L
Q
T
D
L
N
S
E
K
P
-----
P
I
-
E
Q
V
K
S
Q
L
E
-
T
H
F
N
L
A
H
E
T
-------------
Q
--
E
F
-------
S
R
K
N
D
N
A
P
------
V
-------
D
K
L
L
T
N
Y
YN
N
Y
E
V
N
V
----
L
E
F
V
L
Q
MGFSR----
D
L
S
I
P
L
N
V
W
F
V
L
D
M
I
S
Q
L
S
T
S
K
------
Q
D
L
P
--
L
D
Y
Y
L
V
-
L
N
N
S
Q
T
G
KY
S
D
F
V
R
Y
L
I
Y
E
-
A
V
G
A
E
I
HLANRG
P
I
R
----
G
N
V
G
A
G
D
R
K
I
T
F
H
L
L
-----
C
K
K
T
A
R
M
-----
I
L
V
G
D
D
R
ETDFEMSDRSF
V
T
L
----
L
L
------
D
Y
Y
Q
R
V
G
T
T
K
K
I
D
L
L
L
L
T
N
N
F
----
D
T
N
M
N
N
K
L
Q
Q
L
K
I
L
E
S
LNML
K
S
N
C
Y
V
L
-------
D
YQITVDQVTAN
F
N
S
Y
V
E
G
I
P
----------------------------------
A
F
-
R
R
H
E
I
A
N
F
-
L
K
K
R
K
T
-
P
K
N
A
----------
D
E
L
I
F
K
Y
V
G
R
W
-
N
I
C
Y
Q
K
K
F
H
Q
G
N
I
S
IHQISGYLD--------------------------
15
PsiBlast_PDB
52.64
25%
-76
- C5 -
2ZZG
-
SYA_PYRHO
A:
[325-436]
-------------------
V
E
E
L
E
K
A
I
R
P
Y
-------
E
L
-
I
Y
A
I
A
D
H
T
-
K
A
L
T
F
M
L
A
D
-------------
G
V
V
P
S
-------
N
V
K
A
G
Y
L
A
------
R
-------
L
L
I
R
K
S
I
--
R
H
L
R
E
L
G---
L
E
V
P
L
S
---------
E
I
-
V
A
L
H
I
K
E
L
H
K
T
F
P
E
F
K
E
M
E
------
D
I
I
L
E
-----
M
I
-
E
L
E
E
K
K
Y
--
A
E
T
L
R
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
51.60
25%
-89
- C5 -
2ZZF
-
SYA_PYRHO
A:
[325-436]
-------------------
V
E
E
L
E
K
A
I
R
P
Y
-------
E
L
-
I
Y
A
I
A
D
H
T
-
K
A
L
T
F
M
L
A
D
-------------
G
VV
P
S
-------
N
V
K
A
G
Y
L
A
------
R
-------
L
L
I
R
K
S
I
--
R
H
L
R
E
L
G---
L
E
V
P
L
S
---------
E
I
-
V
A
L
H
I
K
E
L
H
K
T
F
P
E
F
K
E
M
E
------
D
I
I
L
E
-----
M
I
-
E
L
E
E
K
K
Y
--
A
E
T
L
R
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
51.01
27%
-114
- C5 -
4IUL
-
IF4G2_HUMAN
A:
[166-248]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
----
I
H
E
S
I
L
H
K
C
I
K
T
L
L
E
K
----
K
K
R
V
Q
L
K
-------
D
-----------
M
G
E
D
L
E
C
L
C
----------------------------------
Q
I
-
M
R
T
V
G
P
R
L
D
H
E
R
A
K
S
-
L
M
D
Q
Y
F
A
R
M
C
S
L
M
L
S
K
E
L
P
A
R
I
R
F
L
-
L
Q
D
T
V
E
-------------------------------------------
1
PsiBlast_PDB
49.32
42%
-281
- C5 -
4EQI
2
?
A:
[6-38]
----------------
Q
V
T
V
D
K
L
K
R
L
E
N
D
F
G
G
-----
R
I
G
V
Y
A
I
D
T
G
S
N
K
T
F
G
Y
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
48.06
23%
54
- C5 -
3JAX
-
?
A:
[807-937]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
R
K
-
A
F
A
K
R
Q
------
Q
Q
L
----
T
A
M
K
V
I
Q
R
N
C
A
A
Y
L
K
-----
L
R
N
W
Q
W
W
-----
R
L
F
T
K
V
K
-----------
P
L
L
----
Q
S
------
A
E
R
E
K
E
M
A
S
M
K
E
E
F
T
R
L
K
E
A
L
E
K
S
E
A
R
R
K
E
L
E
E
K
M
V
S
L
L
Q
E
----
K
-
N
D
L
Q
L
-------
Q
-----------
V
Q
A
E
Q
D
N
L
A
----------------------------------
D
--
A
E
E
R
C
D
Q
L
-
I
K
N
K
I
Q
-
L
E
A
K
----------
V
K
E
M
N
E
R
L
-----------------------------------------------------
45
Fugue
47.74
11%
-77
- C2 -
1WY5
-
TILS_AQUAE
A:
[1-311]
------------MN
P
E
S
R
V
I
R
K
V
L
A
L
Q
N
D
E
K
I
FSGER
R
V
-
L
I
A
F
S
G
G
V
-
D
S
V
V
L
T
D
V
L
-------------
L
--
K
L
K
NYFSLK
E
V
A
L
A
H
F
N
------
H
-------
M
-----
L
--
R
E
S
A
E
R
----
D
E
E
F
C
K
---------
E
F
-
A
K
E
R
N
M
K
-------
I
F
V
G
K
------
E
D
V
R
A
F
A
K
E
N
R
M
-
S
L
E
E
A
G
R
--
F
L
R
Y
K
F
L
K
E
I
-
L
E
S
E
G
F
------
D
C
I
A
T
AH
H
L
N
D
L
L
E
T
S
L
L
F
F
T
R
-----
G
T
G
L
D
G
L
I
GFLP
K
E
E
V
I
R
R
-----------
P
L
Y
----
Y
V
K
R
S
E
I
E
E
Y
A
K
F
K
G
L
R
W
V
E
D
E
T
N
Y
-
E
V
S
----
I
P
R
N
R
I
R
H
R
V
I
P
E
L
K
R
----
I
N
E
N
L
E
D
-------
T
-----------
F
L
K
M
V
K
V
L
R
----------------------------------
A
E
-
R
E
F
L
E
E
E
A
-
Q
K
L
Y
K
E
-
V
K
K
G
----------
N
C
L
D
V
K
K
L
K
E
K
-
P
L
A
L
Q
R
R
V
I
R
K
F
I
G
EKD
Y
E
K
V
E
L
V
R
S
L
L
E
K
G
G
E
V
N
LG
K
G
K
V
L
KRKERWL
11
PsiBlast_PDB
47.43
23%
54
- C5 -
3DTP
-
MYH11_CHICK (first)
A:
[807-937]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
R
K
-
A
F
A
K
R
Q
------
Q
Q
L
----
T
A
M
K
V
I
Q
R
N
C
A
A
Y
L
K
-----
L
R
N
W
Q
W
W
-----
R
L
F
T
K
V
K
-----------
P
L
L
----
Q
S
------
A
E
R
E
K
E
M
A
S
M
K
E
E
F
T
R
L
K
E
A
L
E
K
S
E
A
R
R
K
E
L
E
E
K
M
V
S
L
L
Q
E
----
K
-
N
D
L
Q
L
-------
Q
-----------
V
Q
A
E
Q
D
N
L
A
----------------------------------
D
--
A
E
E
R
C
D
Q
L
-
I
K
N
K
I
Q
-
L
E
A
K
----------
V
K
E
M
N
E
R
L
-----------------------------------------------------
3
PsiBlast_PDB
47.04
42%
-276
- C5 -
4EV4
1
?
A:
[6-36]
----------------
Q
V
T
V
D
K
L
K
R
L
E
N
D
F
G
G
-----
R
I
G
V
Y
A
I
D
T
G
S
N
K
T
F
G
Y
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_CBE
46.82
42%
-251
- C5 -
4EQI
1
?
B:
[6-38]
----------------
Q
V
T
V
D
K
L
K
R
L
E
N
D
F
G
G
-----
R
I
G
V
Y
A
I
D
T
G
S
N
K
T
F
G
Y
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
46.76
28%
-462
* C5 *
1ZW2
-
B:
[1-21]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
-
L
E
A
A
K
S
-
I
A
A
A
----------
T
S
A
L
V
K
A
A
S
A
---------------------------------------------------
2
PsiBlast_PDB
45.32
42%
-268
- C5 -
4EUZ
3
?
A:
[6-36]
----------------
Q
V
T
V
D
K
L
K
R
L
E
N
D
F
G
G
-----
R
I
G
V
Y
A
I
D
T
G
S
N
K
T
F
G
Y
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
43.11
14%
-86
- C5 -
1YKH
-
MED21_YEAST
B:
[2-130]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
R
M
T
Q
-----
L
Q
I
C
L
D
Q
-----
M
T
E
Q
F
C
A
-----------
T
L
N
----
Y
I
------
D
K
N
H
G
F
E
V
V
P
P
E
E
F
S
N
T
I
D
E
L
----
S
T
D
I
I
L
K
T
R
Q
I
N
K
L
I
D
----
S
L
P
G
V
D
V
-------
S
-----------
A
E
E
Q
L
R
K
I
D
----------------------------------
M
--
L
Q
K
K
L
V
E
V
-
E
D
E
K
I
E
-
A
I
K
K
----------
K
E
K
L
M
R
H
V
D
S
M
-
I
E
D
F
V
--------------------------------------------
16
PsiBlast_PDB
40.23
22%
-91
- C5 -
3H8I
4
SQRD_ACIAM
A:
[200-283]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
V
-
H
V
T
V
F
S
P
--
G
E
Y
L
S
D
L
S
P
N
-
S
R
K
A
V
A
------
S
I
Y
----
N
Q
L
G
-------------------
I
K
L
V
-----
H
N
F
K
I
-
K
-----------
E
I
R
----
E
H
------
E
I
V
D
E
K
G
N
T
I
P
A
D
I
T
I
L
L
P
P
Y
----
T
G
N
P
A
L
K
N
S
T
P
D
L
V
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
39.87
22%
-88
- C5 -
3H8L
4
SQRD_ACIAM
A:
[200-283]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
V
-
H
V
T
V
F
S
P
--
G
E
Y
L
S
D
L
S
P
N
-
S
R
K
A
V
A
------
S
I
Y
----
N
Q
L
G
-------------------
I
K
L
V
-----
H
N
F
K
I
-
K
-----------
E
I
R
----
E
H
------
E
I
V
D
E
K
G
N
T
I
P
A
D
I
T
I
L
L
P
P
Y
----
T
G
N
P
A
L
K
N
S
T
P
D
L
V
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
38.57
24%
-41
- C5 -
5A5T
-
?
A:
[510-606]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
L
Q
S
M
P
S
E
Q
I
R
N
Q
L
T
-----
A
M
S
S
V
L
A
-----
K
A
L
E
V
I
K
-----------
P
A
H
----
I
L
------
Q
E
K
E
E
Q
H
Q
L
A
V
T
A
Y
--
L
K
N
S
R
----
K
E
H
Q
R
I
L
A
R
R
Q
T
I
E
E
R
----
K
E
R
L
E
S
L
N
I
Q
R
E
K
E
E
-----------
L
E
Q
R
E
A
E
L
Q
----------------------------------
K
V
-
R
K
-----------------------------------------------------------------------------------------
9
PsiBlast_PDB
36.91
28%
-76
- C5 -
3NNN
2
?
A:
[27-88]
---------------------------------------------------------------------------
F
-------
T
V
D
V
C
Y
D
G
------
E
-------
E
G
M
Y
M
A
L
--
N
E
P
F
D
V
V
I
L
D
I
M
L
P
V
H
---------
D
------
G
W
E
I
L
K
S
M
R
E
S
G
V
N
T
------
P
V
L
M
L
T
A
L
S
D
V
E
-
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------