@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu03360: (2016-06-05 )
MKKIPVTVLSGYLGAGKTTLLNSILQNREGLKIAVIVNDMSEVNIDAGLVKQEGGLSRTDEKLVEMSNGCICCTLREDLLIEVEKLAKDGRFDYIVIESTGISEPIPVAQTFSYIDEEMGIDLTKFCQLDTMVTVVDANRFWHDYQSGESLLDRKEALGEKDEREIADLLIDQIEFCDVLILNKCDLVSEQELEQLENVLRKLQPRARFIRSVKGNVKPQEILHTGLFNFEEASGSAGWIQELTAGHAEHTPETEEYGISSFVYKRRLPFHSTRFYRWLDQMPKNVVRAKGIVWCASHNNLALLMSQAGPSVTIEPVSYWVAALPKLEQEQVKQQEPEILEEWDPEFGDRLTQLVFIGTDLDEETITKELDQCLLTEYEFDSDWSLFEDPFKWKLNQ
Atome Classification :
(20 SA)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20.....-----.-.-----.30........40........---50......-..60........70....------.---.----.----.----80---..---.....---.-----.-----90----.........100....---.-..110.......120......---.130.......140.......150.......160.......170.......180.......190.--........200.......210.......220.......230....---...240.......250.......260.......270.......280----..----.....290.......300.......310....--...320.......330.......340.......-350.........360.....-..370.......380.......390.....---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKKI
P
V
T
V
L
S
G
YLGA
G
K
T
T
L
L
N
S
I
L
Q-----N-R-----EG
L
K
I
A
V
I
VNDMSEVNIDA
G
L
---
V
KQEGGLS-
R
T
D
E
K
L
V
E
MSNG
C
I
C
C
T
L
------
R
---
E
----
D
----
L
----
L
----
I
E
---
V
E
K
L
A---K-----D-----G-----
R
F
D
Y
I
V
I
ESTGISEPI---
P
-
V
A
Q
T
F
S
Y
I
D
E
E
MGI
D
L
T
K
F
CQ---LD
T
M
V
T
V
V
D
A
N
R
F
W
H
D
YQS
G
E
S
L
L
D
R
K
E
ALGE
K
D
E
R
E
I
A
D
L
L
I
D
Q
I
E
F
C
D
V
L
I
LNKCDLV
S
E
--
Q
--
E
L
E
Q
L
E
N
V
L
R
K
L
Q
P
R
A
R
F
I
R
S
V
KGNV
K
P
Q
E
I
L
H
T
G
LFNFEEASGS---A
G
W
I
Q
E
L
TAGHAEHTP
E
T
E
EY
G
I
S
S
F
V
Y
K
RRLPFH
S
T
R
F
Y
R
W
L
D
QM----
P
K
----
N
V
V
RAK
G
I
V
W
C
ASHN
N
L
A
L
L
M
SQAGP
S
V
T
I
E
P
--
V
S
Y
W
V
A
ALPKL
E
Q
E
Q
V
K
QQE
P
E
I
L
E
EWD
P
E
F
G
D
-
R
--
L
T
Q
L
V
F
I
GTDL
D
E
E
T
I
T
-
K
E
L
D
Q
C
L
L
T
E
YEFDSDWSLFEDP
F
K
WKLNQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
90.90
31%
-136
- C4 -
1NIJ
-
YJIA_ECOLI
A:
[2-317]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
P
I
A
V
T
L
L
T
G
F
L
G
A
G
K
T
T
L
L
R
H
I
L
N
-----
E
-
Q
-----
H
G
Y
K
I
A
V
I
E
N
E
F
G
E
V
S
V
D
D
Q
L
---
I
G
D
-------
R
A
T
Q
I
K
T
L
T
N
G
C
I
C
C
S
R
------
S
---
N
----
E
----
L
----
E
----
D
A
---
L
L
D
L
L
---
D
-----
N
L
D
K
GN
I
-----
Q
F
D
R
L
V
I
E
C
T
G
M
A
D
P
G
---
P
-
I
I
Q
T
F
F
S
H
E
-----
V
L
C
Q
R
Y
L
---
L
D
G
V
I
A
L
V
D
A
V
H
A
D
E
Q
M
N
Q
-------------------
F
T
I
A
Q
S
Q
V
G
Y
A
D
R
I
L
L
T
K
T
D
V
A
G
E
------
A
E
K
L
H
E
R
L
A
R
I
N
A
R
A
P
V
Y
T
V
T
H
G
D
I
D
L
G
L
L
F
N
T
N
G
F
M
L
E
E
N
V
V
S
---------
T
K
P
-
R
-
F
H
F
I
A
D
K
Q
N
D
I
S
S
I
V
V
E
L
D
Y
P
V
D
I
S
E
V
S
R
V
M
E
N
L
L
L
E
S
A
D
----
K
L
L
R
Y
K
G
M
L
W
I
D
G
E
P
N
-
R
L
L
F
Q
G
V
Q
R
L
Y
S
A
D
W
--
D
R
P
W
---------
G
D
----------------
E
K
-
P
--
H
S
T
M
V
F
I
G
I
Q
L
P
E
E
E
I
R
-
A
A
F
A
G
L
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
Fugue
88.91
29%
-131
- C4 -
1NIJ
-
YJIA_ECOLI
A:
[2-318]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
P
I
A
V
T
L
L
T
G
F
L
G
A
G
K
T
T
L
L
R
H
I
L
N
-----
E
-
Q
-----
H
G
Y
K
I
A
V
I
E
N
E
F
G
E
V
S
V
D
D
Q
L
---
I
G
D
R
A
-------
T
Q
I
K
T
L
T
N
G
C
I
C
C
S
R
------
S
---
N
----
E
----
L
----
E
----
D
A
---
L
L
D
L
L
---
D
-----
N
-----
L
D
K
GNI
Q
F
D
R
L
V
I
E
C
T
G
M
A
D
P
G
---
P
-
I
I
Q
T
F
F
S
-----
H
E
V
L
C
Q
R
Y
L
---
L
D
G
V
I
A
L
V
D
A
V
H
A
D
E
Q
M
N
Q
F
-------------------
T
I
A
Q
S
Q
V
G
Y
A
D
R
I
L
L
T
K
T
D
V
A
G
E
--
A
----
E
K
L
H
E
R
L
A
R
I
N
A
R
A
P
V
Y
T
V
T
H
G
D
I
D
L
G
L
L
F
N
T
N
G
F
M
L
E
E
-----------
N
V
V
S
T
K
P
R
F
H
F
I
A
D
K
Q
N
D
I
S
S
I
V
V
E
L
D
Y
P
V
D
I
S
E
V
S
R
V
M
E
N
L
----
L
L
E
SAD
K
L
L
R
Y
K
G
M
L
W
I
D
G
E
P
N
R
L
L
F
Q
G
V
Q
--------------------------
R
L
Y
S
A
D
W
D
R
P
W
G
D
E
--
K
-
P
--
H
S
T
M
V
F
I
G
I
Q
L
P
E
E
E
I
R
-
A
A
F
A
G
L
----------------------
R
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
81.66
27%
-124
- C4 -
1NIJ
-
YJIA_ECOLI
A:
[2-309]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
P
I
A
V
T
L
L
T
G
F
L
G
A
G
K
T
T
L
L
R
H
I
L
N
-----
E
-
Q
-----
H
G
Y
K
I
A
V
I
E
N
E
F
G
E
V
S
V
D
D
Q
L
---
I
G
D
R
A
T
Q
I
-
K
T
------
L
T
N
G
C
I
C
C
S
R
------
S
---
N
----
E
----
L
----
E
----
D
A
---
L
L
D
L
L
---
D
N
L
D
K
G
N
-----
I
-----
Q
F
D
R
L
V
I
E
C
T
G
M
A
D
P
G
---
P
-
I
I
Q
T
F
--
F
S
H
E
V
------
L
C
Q
R
Y
L
L
D
G
V
I
A
L
V
D
A
----------------
V
H
A
D
E
Q
M
N
Q
F
T
I
A
Q
---
S
Q
V
G
Y
A
D
R
I
L
L
T
K
T
D
V
A
G
E
--
A
----
E
K
L
H
E
R
L
A
R
I
N
A
R
A
P
V
Y
T
V
T
H
G
D
I
D
L
G
L
L
F
N
T
N
G
F
M
L
E
E
-----------
N
V
V
S
T
K
P
R
F
H
F
I
A
D
K
Q
N
D
I
S
S
I
V
V
E
L
D
Y
P
V
D
I
S
E
V
S
R
V
M
E
N
L
L
L
E
S
A
D
----
K
L
L
R
Y
K
G
M
L
W
I
D
G
E
P
N
R
L
L
F
----------
Q
G
--
V
Q
R
L
Y
S
A
------------------
D
W
D
R
P
W
G
D
-
E
K
P
H
S
T
M
V
F
I
G
I
Q
L
P
E
E
E
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
81.42
26%
-120
- C4 -
4IXN
4
YJIA_ECOLI
A:
[1-309]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
P
I
A
V
T
L
L
T
G
F
L
G
A
G
K
T
T
L
L
R
H
I
L
N
-----
E
-
Q
-----
H
G
Y
K
I
A
V
I
A
N
E
F
G
E
V
S
V
D
D
Q
L
---
I
G
D
R
A
T
Q
I
-
K
T
------
L
T
N
G
C
I
A
A
S
R
------
S
---
N
----
E
----
L
----
E
----
D
A
---
L
L
D
L
L
---
D
N
L
D
K
G
N
-----
I
-----
Q
F
D
R
L
V
I
E
C
T
G
M
A
D
P
G
---
P
-
I
I
Q
T
F
--
F
S
H
E
V
------
L
C
Q
R
Y
L
L
D
G
V
I
A
L
V
D
A
----------------
V
H
A
D
E
Q
M
N
Q
F
T
I
A
Q
---
S
Q
V
G
Y
A
D
R
I
L
L
T
K
T
D
V
A
G
E
--
A
----
E
K
L
H
E
R
L
A
R
I
N
A
R
A
P
V
Y
T
V
T
H
G
D
I
D
L
G
L
L
F
N
T
N
G
F
M
L
E
E
-----------
N
V
V
S
T
K
P
R
F
H
F
I
A
D
K
Q
N
D
I
S
S
I
V
V
E
L
D
Y
P
V
D
I
S
E
V
S
R
V
M
E
N
L
L
L
E
S
A
D
----
K
L
L
R
Y
K
G
M
L
W
I
D
G
E
P
N
R
L
L
F
----------
Q
G
--
V
Q
R
L
Y
S
A
------------------
D
W
D
R
P
W
G
D
-
E
K
P
H
S
T
M
V
F
I
G
I
Q
L
P
E
E
E
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
79.09
27%
-119
- C4 -
4IXM
5
YJIA_ECOLI
A:
[1-309]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
P
I
A
V
T
L
L
T
G
F
L
G
A
G
K
T
T
L
L
R
H
I
L
N
-----
E
-
Q
-----
H
G
Y
K
I
A
V
I
E
N
E
F
G
E
V
S
V
D
D
Q
L
---
I
G
D
R
A
T
Q
I
-
K
T
------
L
T
N
G
C
I
C
C
S
R
------
S
---
N
----
E
----
L
----
E
----
D
A
---
L
L
D
L
L
---
D
N
L
D
K
G
N
-----
I
-----
Q
F
D
R
L
V
I
E
C
T
G
M
A
D
P
G
---
P
-
I
I
Q
T
F
--
F
S
H
E
V
------
L
C
Q
R
Y
L
L
D
G
V
I
A
L
V
D
A
----------------
V
H
A
D
E
Q
M
N
Q
F
T
I
A
Q
---
S
Q
V
G
Y
A
D
R
I
L
L
T
K
T
D
V
A
G
E
--
A
----
E
K
L
H
E
R
L
A
R
I
N
A
R
A
P
V
Y
T
V
T
H
G
D
I
D
L
G
L
L
F
N
T
N
G
F
M
L
E
E
-----------
N
V
V
S
T
K
P
R
F
H
F
I
A
D
K
Q
N
D
I
S
S
I
V
V
E
L
D
Y
P
V
D
I
S
E
V
S
R
V
M
E
N
L
L
L
E
S
A
D
----
K
L
L
R
Y
K
G
M
L
W
I
D
G
E
P
N
R
L
L
F
----------
Q
G
--
V
Q
R
L
Y
S
A
------------------
D
W
D
R
P
W
G
D
-
E
K
P
H
S
T
M
V
F
I
G
I
Q
L
P
E
E
E
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
Fugue
58.87
19%
-64
- C4 -
4XC8
4
ICMF_CUPMC
A:
[42-1113]
GPANK
V
R
F
V
T
A
A
S
L
FDGHDAS
I
N
I
M
R
R
I
L
Q
S
Q
GCEVIHLGHNRS
V
Q
E
V
V
T
A
A
L
Q
E
DVQ
G
I
A
I
S
S
YQGG
H
V
E
Y
F
K
Y
M
I
D
L
L
R
E
H
GGEH
I
Q
V
F
G
G
GGGVIV
P
D
E
I
R
E
L
Q
A
Y
GVA
R
I
Y
S
P
E
D
G
Q
R
MG
L
A
G
M
I
T
D
M
A
Q
R
C
DIDLTRYAPTTL
D
T
V
V
A
GD
R
R
A
L
A
Q
L
I
T
A
L
E
N
GKAD
P
E
L
V
S
A
L
H
A
Q
A
K
A
A
A
V
P
V
L
G
I
T
G
T
G
G
A
G
K
S
S
L
T
D
E
L
I
R
R
F
R
L
D
Q
-
D
-----
D
A
L
S
I
A
V
I
S
I
D
P
S
R
R
K
S
G
G
A
L
---
L
G
D
R
I
R
M
N
-
A
I
N
H
P
N
I
F
M
R
S
L
A
T
R
E
A
G
------
S
---
E
----
I
----
S
QA--
L
----
P
D
---
V
I
A
A
C
---
K
-----
A
-----
A
-----
R
F
D
L
V
I
V
E
T
S
G
I
G
Q
G
D
---
A
---------------
A
I
V
P
H
V
D
---
L
S
L
Y
V
M
T
P
E
F
G
A
--------
A
S
Q
L
E
K
----------------
I
D
M
L
D
F
A
D
F
V
A
I
N
K
F
D
--
R
K
--
G
--
A
Q
D
A
W
R
D
V
A
K
Q
V
Q
R
N
R
E
Q
W
H
S
---
R
A
E
D
M
P
V
Y
G
T
Q
A
S
R
F
N
D
D
G
V
T
M
L
Y
Q
G
L
V
G
A
L
G
A
R
G
M
S
L
K
P
G
T
L
P
N
L
E
G
R
I
S
T
G
Q
N
V
I
V
P
P
A
R
-
S
R
Y
L
A
E
L
----
A
D
----
T
V
R
A
Y
H
R
R
V
V
A
Q
S
K
L
A
R
E
R
Q
Q
L
R
A
A
H
D
M
L
Q
G
A
GH
E
S
A
A
L
E
T
L
A
S
E
R
D
V
S
L
G
A
V
E
R
K
L
L
A
M
W
P
Q
M
Q
Q
A
Y
S
--
G
D
E
Y
V
E
I
R
T
G
L
I
S
T
T
L
S
G
T
K
I
R
K
V
V
L
P
R
F
E
D
E
G
E
I
------
L
K
W
L
M
R
E
NVPGSFPYTAGVFAFKREGEDP
T
R
M
F
A
G
E
G
D
A
F
R
T
N
R
R
F
K
L
V
S
EGMEAK
R
L
S
T
A
F
D
S
V
T
L
Y
GEDPHERPDIYGKVGNS
G
V
S
I
A
T
L
E
D
M
K
V
L
Y
DGFDLTNPS
T
S
V
S
M
T
I
N
GP
A
P
T
I
L
A
M
F
M
N
T
A
I
D
Q
Q
I
D
R
F
R
A
D
N
GRDPT
A
D
E
E
A
K
I
R
A
W
V
L
Q
N
V
R
G
T
V
QAD
I
L
K
E
D
Q
GQNTCIFS
T
E
F
S
L
K
V
M
G
D
I
Q
E
Y
F
V
H
H
QVRNFYSVSISG
Y
H
I
A
E
A
GAN
P
I
S
Q
L
A
F
T
L
A
N
G
F
T
Y
V
E
A
Y
L
A
R
GMHIDDFAPN
L
S
F
F
F
S
N
G
MD
P
E
Y
S
V
L
G
R
V
A
R
R
I
W
A
V
T
M
R
DKYGANDRSQ
K
L
K
Y
H
I
Q
T
S
GRSLHAQEIDF
N
D
I
R
T
T
L
Q
A
L
I
A
I
Y
D
NCN
S
L
H
T
N
A
YDEAITTPT
A
E
S
V
R
R
A
L
A
I
Q
L
I
I
N
REWGVAKCENPNQGS
F
L
I
E
E
L
T
D
L
V
E
E
A
V
L
Q
E
F
E
R
I
A
E
R
GG
V
L
G
A
M
E
T
G
Y
Q
R
G
K
I
Q
E
E
S
L
Y
Y
E
Q
L
K
H
D
GTLPIIGVNTFRNPNGDPRSS
E
D
E
K
Q
S
Q
L
H
R
L
T
E
F
H
G
A
H
QAD
A
E
A
M
L
A
R
L
R
Q
A
V
I
D
NRN
V
F
A
V
L
M
D
A
V
R
V
CS
L
G
Q
I
T
H
A
L
F
E
V
GGQYRRNM
22
HHSearch
53.49
21%
-131
- C4 -
2HF9
4
HYPB_METJA
A:
[37-204]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
V
V
A
F
D
F
M
G
A
I
G
S
G
K
T
L
L
I
E
K
L
I
D
-----
N
-
L
K----
D
K
Y
K
I
A
C
I
A
G
D
V
I
A
-
K
F
D
A
E
R
---
M
E
K
-------
H
G
A
K
V
V
P
L
N
T
G
K
E
C
H
L
D
------
A
---
H
----
L
----
V
----
G
----
H
A
---
L
E
D
L
N
---------
L
-----
D
-----
E
I
D
L
L
F
I
E
N
V
G
N
L
I
C
P
---
A
----
D
F
-------------
D
L
G
---
T
H
K
R
I
V
V
I
S
T
T
E
G
D
D
T
I
----------------------
E
K
H
P
G
I
M
K
T
A
D
L
I
V
I
N
K
I
D
L
A
D
A
VG
A
--
D
I
K
K
M
E
N
D
A
K
R
I
N
P
D
A
E
V
V
L
L
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
52.97
20%
-148
* C4 *
3P32
2
Y1496_MYCTU
A:
[78-233]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
A
H
R
V
G
I
T
G
V
P
G
V
G
K
S
T
A
I
E
A
L
G
M
-----
H
-
L
I
E
---
R
G
H
R
V
A
V
L
A
V
D
------------------------
M
A
R
L
A
V
H
P
N
A
Y
I
R
P
S
P
-----------GT
L
G
G
----
V
----
T
R
A
T
-
R
E
---
T
V
V
L
L
---
E
-----
A
-----
A
-----
G
F
D
V
I
L
I
E
T
V
G
V
G
Q
S
E
---
V
---
A
--------------
V
A
N
M
---
V
D
T
F
V
L
L
T
L
A
R
T
G
D
Q
-
L
---------------------
Q
G
I
K
K
G
V
L
E
L
A
D
I
V
V
V
N
K
A
D
G
E
H
H
--
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
52.71
19%
-137
- C4 -
4LPS
12
HYPB_HELPY
A:
[44-214]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
G
L
Y
V
L
N
F
M
S
S
P
G
S
G
K
T
T
M
L
E
N
L
A
D
-----
F
-
K
------
D
F
K
F
C
V
V
E
G
D
L
Q
-
T
N
R
D
A
D
R
---
L
R
K
-------
K
G
V
S
A
H
Q
I
T
T
G
E
A
C
H
L
E
------
A
--------
S
----
M
----
I
----
E
G
---
A
F
D
L
L
---
K
D
E
GA-
L
-----
E
-----
K
S
D
F
L
I
I
E
N
V
G
N
L
V
C
P
---
S
----
S
Y
-------------
N
L
G
---
A
A
M
N
I
V
L
L
S
V
P
E
G
D
D
K
V
L
----------------------
K
Y
P
T
M
F
M
C
A
D
A
V
I
I
S
K
A
D
M
V
E
V
FN
F
--
R
V
S
Q
V
K
E
D
M
Q
K
L
K
P
E
A
P
I
F
L
M
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
51.47
24%
-129
- C4 -
4XC8
3
ICMF_CUPMC
A:
[228-399]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
P
V
L
G
I
T
G
T
G
G
A
G
K
S
S
L
T
D
E
L
I
R
-----
R
-
F
R
L
D
Q
D
D
A
L
S
I
A
V
I
S
I
D
P
S
R
R
K
S
G
G
A
L
---
L
G
D
--------
R
I
R
M
N
A
I
N
H
P
N
I
F
M
R
S
L
A
TREA
G
---
S
----
E
----
I
----
S
----
Q
A
---
L
P
D
V
I
A
A
C
K
-----
A
-----
A
-----
R
F
D
L
V
I
V
E
T
S
G
I
G
Q
G
D
---
A
-
A
I
----------------
V
P
H
---
V
D
L
S
L
Y
V
M
T
P
E
F
G
A
A
S
Q
----------------------
L
E
K
I
D
M
L
D
F
A
D
F
V
A
I
N
K
F
D
R
K
G
A
--
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
50.85
23%
-93
- C4 -
4HI0
2
UREG_HELPY
E:
[1-178]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
K
I
G
V
C
G
P
V
G
S
G
K
T
A
L
I
E
A
L
T
R
-----
H
-
M
S----
K
D
Y
D
M
A
V
I
T
N
D
I
Y
T
K
E
-
D
A
E
F
---
M
C
K
-
N
S
V
M
-
P
R
E
R
I
I
G
V
E
T
G
G
C
P
H
T
A
I
------
R
---
E
----
D
----
A
----
S
----
M
N
LEA
V
E
E
M
H
---
G
R----
F
-----
P
-----
N
L
E
L
L
L
I
E
S
G
G
D
N
L
--------
S
A
------------
T
F
N
P
E
L
---
A
D
F
T
I
F
V
I
D
V
A
E
G
D
K
I
P
----------------------
R
K
G
G
P
G
I
T
R
S
D
L
L
V
I
N
K
I
D
L
A
P
Y
VG
A
--
D
L
K
V
M
E
R
D
S
K
K
M
R
G
E
K
P
F
I
F
T
N
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
49.64
21%
-152
- C4 -
2WWW
2
MMAA_HUMAN
A:
[73-232]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
F
R
V
G
L
S
G
P
P
G
A
G
K
S
T
F
I
E
Y
F
G
K
-----
M
-
L
T
E
---
R
G
H
K
L
S
V
L
A
V
D
P
------------------------
T
E
L
S
R
D
M
N
A
Y
I
R
P
S
----------------------TRT
T
N
----
E
A
---
I
L
L
-
C
---
E
-----
G
-----
A
-----
G
Y
D
I
I
L
I
E
T
V
G
V
--
S
E
---
F
----
A
V
-------------
A
D
M
---
V
D
M
F
V
L
L
L
P
P
A
----------------------------------
I
E
M
A
D
L
V
A
V
T
K
S
D
G
D
L
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
48.44
20%
-119
- C4 -
2P67
-
ARGK_ECOLI
A:
[56-210]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
R
L
G
V
T
G
T
P
G
A
G
K
S
T
F
L
E
A
F
G
M
-----
L
-
L
I
R
---
E
G
L
K
V
A
V
I
A
V
D
P
S
---------------
N
D
L
A
R
A
E
A
A
F
I
R
P
V
P
S
-----
G
-------
A
---
S
----
Q
----
R
----
A
----
R
E
---
L
M
L
L
C
---
E
-----
A
-----
A
-----
G
Y
D
V
V
I
V
E
T
V
G
V
G
Q
S
E
---
T
----
E
V
-------------
A
R
M
---
V
D
C
F
I
S
L
Q
I
A
-------
Q
---------------------
G
I
K
K
G
L
M
E
V
A
D
L
I
V
I
N
K
D
D
G
D
N
H
--
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
48.43
21%
-114
- C4 -
1YRB
3
GPN_PYRAB
A:
[13-197]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
M
I
V
V
F
V
G
T
A
G
S
G
K
T
T
L
T
G
E
F
G
R
-----
Y
-
L
E----
D
N
Y
K
V
A
Y
V
N
L
D
T
G
V
K
E
L
P
Y
E
P
SID
V
R
E
-
F
V
T
V
-
E
E
I
M
R
E
G
Y
G
P
N
G
A
I
V
E
S
Y
------
D
R
L
M
E
----
K
----
F
----
N
----
E
Y
---
L
N
K
I
L
---
R
L
----
E
-----
K
-----
E
N
D
Y
V
L
I
D
T
P
G
Q
M
E
T
F
---
L
-
F
H
E
F
G
V
R
--------
L
M
E
N
L
P
---
Y
P
L
V
V
Y
I
S
D
P
E
I
L
K
K
P
N
D
Y
C
-------------
F
V
R
F
F
A
L
L
I
D
L
R
L
G
A
T
T
I
P
A
L
N
K
V
D
L
L
S
E
--
E
--
E
K
E
R
H
R
K
Y
F
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
47.85
19%
-175
- C4 -
4NKR
3
?
A:
[1-114]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
P
I
V
Q
V
V
G
F
Q
N
S
G
K
T
T
F
I
E
R
I
L
E
-----
K
-
A
S
E
---
Q
G
L
N
L
G
C
L
K
H
H
--------
D
R
---
Y
Q
A
-------
A
G
A
D
V
T
A
V
E
G
A
G
V
L
Q
L
T
------
A
--------
R
----
R
----
L
----
W
D
---
L
T
R
L
I
---
E
L
Y
Q
--
F
-----
L
-----
E
T
D
C
L
L
I
E
G
F
K
K
A
-
P
Y
---
P
-
K
V
V
I
L
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
46.38
19%
-129
- C4 -
1J8M
-
SRP54_ACIAM
F:
[97-254]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
P
Y
V
I
M
L
V
G
V
Q
G
T
G
K
T
T
T
A
G
K
L
A
Y
-----
F
-
Y
KK---
K
G
F
K
V
G
L
V
G
A
D
V
Y
R
P
A
A
L
E
Q
L
----
Q
Q
----------
L
G
Q
Q
I
G
V
P
V
Y
G
E
P
G
------
E
---
K
----
D
----
V
----
V
GIAK
R
G
---
V
E
K
F
L
---------
S
-----
E
-----
K
M
E
I
I
I
V
D
T
A
G
R
H
G
Y
G
EEA
A
-
L
L
E
E
M
K
N
--------
I
Y
E
A
I
K
---
P
D
E
V
T
L
V
I
D
A
S
I
G
Q
K
A
Y
D
-------------------
L
A
S
K
F
N
Q
-
A
S
K
I
G
T
I
I
I
T
K
M
D
G
T
A
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
45.77
18%
-90
- C4 -
2WSM
1
?
A:
[11-213]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------L
A
E
N
K
R
L
A
E
K
N
R
E
A
L
R
E
S
G
T
V
A
V
N
I
M
G
A
I
G
S
G
K
T
L
L
I
E
R
T
I
E
-----
R
I
G
-----
N
E
V
K
I
G
A
M
L
G
D
V
V
S
-
K
A
D
Y
E
R
---
V
R
R
F
G
-------
I
K
A
E
A
I
S
T
G
K
E
C
H
L
D
------
A
---
H
----
M
----
I
----
Y
----
H
R
---
L
K
K
F
S
---
D
------------------
C
D
L
L
L
I
E
N
V
G
---------------------------------------
N
L
I
C
P
V
D
F
D
L
G
E
N
Y
R
V
V
M
V
S
V
T
E
--
G
D
D
V
V
E
K
H
P
E
I
F
R
V
----
A
D
L
I
V
I
N
K
V
A
L
A
E
A
--
V
GA
D
V
E
K
M
K
A
D
A
K
L
I
N
P
R
A
K
I
I
E
M
---
D
L
K
T
G
K
G
F
E
E
W
I
D
F
L
R
G
I
L
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
45.77
19%
-115
- C4 -
2WSM
1
?
A:
[29-195]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
T
V
A
V
N
I
M
G
A
I
G
S
G
K
T
L
L
I
E
R
T
I
E
-----
R
-
I
G----
N
E
V
K
I
G
A
M
L
G
D
V
V
S
K
-
A
D
Y
E
R
---
V
R
R
-------
F
G
I
K
A
E
A
I
S
T
G
K
E
C
H
L
D
------
A
---
H
----
M
----
I
----
Y
----
H
R
---
L
K
K
-----------
F
-----
S
-----
D
C
D
L
L
L
I
E
N
V
G
N
L
I
---------
C
P
V
D
-----------
F
D
L
G
---
E
N
Y
R
V
V
M
V
S
V
T
E
G
D
D
V
V
----------------------
E
K
H
P
E
I
F
R
V
A
D
L
I
V
I
N
K
V
A
L
A
E
A
VG
A
--
D
V
E
K
M
K
A
D
A
K
L
I
N
P
R
A
K
I
I
E
M
D
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
45.17
20%
-112
- C4 -
2V3C
-
SRP54_METJA
C:
[100-276]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
N
V
I
L
L
V
G
I
Q
G
S
G
K
T
T
T
A
A
K
L
A
R
-----
Y
-
I
QK---
R
G
L
K
P
A
L
I
A
A
D
T
Y
R
P
A
A
Y
E
Q
L
----
K
Q
-----------
L
-
A
E
K
I
H
V
P
I
Y
G
D
------
E
TRT
K
----
S
----
P
----
V
----
D
I
---
V
K
E
G
M
E--
K
-----
F
-----
K
-----
K
A
D
V
L
I
I
D
T
A
G
R
H
K
E
E
K--
G
-
L
L
E
E
M
K
Q
--------
I
K
E
I
T
N
---
P
D
E
I
I
L
V
I
D
G
T
I
G
Q
Q
A
G
I
-------------------
Q
A
K
A
F
K
E
A
V
G
E
I
G
S
I
I
V
T
K
L
D
G
S
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
44.63
19%
-127
- C4 -
3E70
3
?
C:
[128-283]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
P
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
-----
W
-
L
KN---
H
G
F
S
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
---
E
E
H
---------
A
K
--
R
I
G
V
K
V
I
K
H
S
Y
------
G
---
A
----
D
PAAV
A
----
Y
----
D
A
---
I
Q
H
A
----
K
-----
A
-----
R
-----
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
---
R
N
L
M
D
E
M
K
--------
K
I
A
R
V
T
K
---
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
-------------------
Q
A
R
Q
F
N
-
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------