@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu03560: (2016-06-06 )
MEKYMSLLTRIEEMMQSTSYQEGDRLPSIRQLSARYQVSKSTVIRALQELEKRHLIYSVPKSGYYIVKKSGKSKSGQPGPIDFATSAPDPDVFPYLDFQHCINKAIDTYKNDLFIYGTPKGLPSLIRVLRKLLATQQVFADERHIFITSGVQQALSLLCAMPFPNGKEKIAIEQPGYHLMVEQLETLGIPAIGVKRTEEGLDIAKVERLFQTESIKFFYTMPRFHNPLGCSLSERDKQELVRLAEAYDVYLVEDDYLGDLEENKKADPLYAYDLSSHVIYLKSFSKMMFPGLRVGAAVLPEALTDTFYAYKKLNDIDCSMISQAALEIYLKSGMYGRHKEKIRDSYKERSLRLHQAIRTHRQLGSGRFTFSSGQAPCMHTHLVLPQDLPASRVIHRLEKQGVLLEAIDRHYLSDYPKENLLKINISNVKTEDIERGVKLLMSHL
Atome Classification :
(20 SA)
------------.........10........20........30........40........50........60.....----------------...70....-----------...----------------.80........90........100..--...---..110.......120.......130..-.----.-.-..-140---........150.......160.......170........180.......190.......200.......210---.-----.-----------.......220.......230.-......240.....-.-.250.......260....-..-.-.270.---....-----..280.......290.......-300.......310..-...-..320.-......330---....-.-..340.......350.......360...--.-..-.370.......380.......390..-...-..400...--....410.......---420.......430.......440..-
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------
M
E
K
Y
M
S
L
L
T
R
I
E
E
M
M
Q
STSYQEGDRL
P
S
I
R
Q
L
S
A
R
YQV
S
K
S
T
V
I
R
A
L
Q
E
L
E
KR
H
L
I
Y
SVPKS
G
Y
Y
I
----------------
V
KKSGKSKS-----------GQP----------------GPIDFATSAPDPDV
F
P
Y
L
D
F
Q
H
C
I
N
K
--
A
I
D
---TYKN
D
L
F
I
Y
GTPK
G
L
P
S
L
I
R
V
L
R
K
L
L
A
-
T
----
Q
-
Q
-
V
F-AD----E
R
H
I
F
I
T
S
G
V
Q
Q
A
L
S
L
L
CAMPFPNGK
E
K
I
-
A
IEQPG
Y
H
L
M
V
E
Q
L
E
T
LGIPAIGVKRTEEGL
D
I
A
K
V
E
R
L
F
-----Q-----T-----------E
S
I
K
F
F
Y
TMPRFHNPLGCSL
S
-
E
R
D
K
Q
E
L
V
R
L
A
E
A
Y
-
D
-
V
Y
L
VEDDYLG
D
L
E
-ENKK-AD-
P
-
L
Y
A
Y
D---LSSH-----
V
I
Y
L
K
S
F
S
K
M
MFPG
L
R
V
G
A
A
V
L
-
P
E
A
L
T
D
T
F
Y
A
Y
K
KLN-DI
D
-
C
S
M
I
S
Q
-
A
A
L
E
I
Y
L
KS---GMYG-
R
-
H
K
E
K
I
R
D
S
Y
K
E
R
S
L
R
L
H
Q
A
I
R
T
H
R
QLGS--
G
-
R
F
-
T
FSSGQAP
C
M
H
T
H
L
VLPQDL
P
A
S
R
V
I
-
H
R
L
-
E
KQ
G
V
L
L
E
--
A
I
D
R
H
Y
L
S
DYPKE
N
---
L
L
K
I
NISNV
K
T
E
D
I
E
R
G
V
K
L
L
M
SHL-
24
Fugue
70.92
24%
-114
- C2 -
4MGR
3
GABR_BACSU
A:
[2-469]
D
I
T
I
T
L
DRSEQA
D
Y
I
Y
Q
Q
I
Y
Q
K
L
K
K
E
I
L
S
R
N
L
L
P
H
S
K
V
P
S
K
R
E
L
A
E
N
L
K
V
S
V
N
S
V
N
S
A
Y
Q
Q
L
L
A
E
G
Y
L
Y
A
I
E
R
K
G
F
F
V
E
ELDMFSA
E
E
H
P
P
F
AL
P
D
D
L
K
E
I
H
I
-----------
D
Q
S
----------------
D
W
I
S
F
S
H
M
S
S
D
T
D
H
F
P
I
K
S
W
F
R
C
E
Q
K
--
A
A
S
---
R
S
Y
R
T
L
G
D
M
S
H
P
Q
G
I
Y
E
V
R
A
A
I
T
R
L
I
S
-
L
----
T
-
R
G
V
K
-
C
R
----
P
E
Q
M
I
I
G
A
G
T
Q
V
L
M
Q
L
L
T
E
L
L
P
K
E
A
--
V
Y
-
A
M
E
E
P
G
Y
R
R
M
Y
Q
L
L
K
N
A
G
K
Q
V
K
T
I
M
L
D
E
K
G
M
S
I
A
E
I
T
R
Q
-------------------------
Q
P
D
V
L
V
T
T
P
S
H
Q
F
P
S
G
T
I
M
P
-
V
S
R
R
I
Q
L
L
N
W
A
A
E
E
-
P
R
R
Y
I
I
E
D
D
Y
D
S
E
F
T
-
Y
D
V
D
-
S
I
-
P
A
L
Q
S
L
D
---
R
F
Q
N
-----
V
I
Y
M
G
T
F
S
K
S
L
L
P
G
L
R
I
S
Y
M
V
L
-
P
P
E
L
L
R
A
-
Y
K
Q
R
G
Y
D
-
L
Q
T
-
C
S
S
L
T
Q
-
L
T
L
Q
E
F
I
E
S
---
G
E
Y
Q
-
K
-
H
I
K
K
M
K
Q
H
Y
K
E
K
R
E
R
L
I
T
A
L
E
A
E
F
---
S
--
G
-
E
V
-
T
V
K
G
A
N
A
G
-
L
H
F
V
T
E
F
D
T
R
R
T
E
Q
D
I
L
-
S
H
A
-
A
G
L
Q
L
E
I
F
--
G
M
S
R
F
N
L
K
E
N
K
R
Q
T
GR
P
A
L
I
I
G
F
A
R
L
K
E
E
D
I
Q
E
G
V
Q
R
L
F
K
A
V
Y
33
HHSearch
68.44
24%
-116
- C2 -
4TV7
-
GABR_BACSU
A:
[15-463]
-------------
Y
I
Y
Q
Q
I
Y
Q
K
L
K
K
E
I
L
S
R
N
L
L
P
H
S
K
V
P
S
K
R
E
L
A
E
N
L
K
V
S
V
N
S
V
N
S
A
Y
Q
Q
L
L
A
E
G
Y
L
Y
A
I
E
R
K
G
F
F
V
----------------
E
E
L
D
M
F
S
A
-ALPDDLKEIHI--------------------
W
I
S
F
S
H
M
--
D
T
D
H
F
P
I
K
S
W
F
R
C
E
Q
K
--
A
A
S
---
R
S
Y
-----
M
S
H
P
Q
G
I
Y
E
V
R
A
A
I
T
R
L
I
S
-
L
T---
R
-
G
-
V
K
-
C
R
----
P
E
Q
M
I
I
G
A
G
T
Q
V
L
M
Q
L
L
T
E
-
L
L
-
P
K
E
A
V
Y
-
A
M
E
E
P
G
Y
R
R
M
Y
Q
L
L
K
N
A
G
K
Q
V
K
T
I
M
L
D
E
K
G
M
S
I
A
E
I
T
R
-------------------------
Q
Q
P
D
V
L
V
T
T
P
S
H
Q
F
P
S
G
T
I
M
P
-
V
S
R
R
I
Q
L
L
N
W
A
A
E
E
P
R
-
R
Y
I
I
E
D
D
Y
D
S
E
F
T
-
Y
D
V
D
S
I
P
-
A
-
L
Q
S
L
D
---
R
F
Q
N
-----
V
I
Y
M
G
T
F
S
K
S
L
L
P
G
L
R
I
S
Y
M
V
L
-
P
P
E
L
L
R
A
Y
K
Q
R
-
G
Y
D
-
L
Q
T
-
C
S
S
L
T
Q
-
L
T
L
Q
E
F
I
E
S
---
G
E
Y
Q
-
K
-
H
I
K
K
M
K
Q
H
Y
K
E
K
R
E
R
L
I
T
A
L
E
A
--
E
F
S
G
--
E
--
V
-
T
V
K
G
-
A
N
A
G
L
H
F
V
T
E
-
D
T
R
R
T
E
Q
D
I
L
-
S
H
A
-
A
G
L
Q
L
E
I
F
--
G
M
S
R
F
-------
R
P
---
A
L
I
I
G
F
A
R
L
K
E
E
D
I
Q
E
G
V
Q
R
------
7
PsiBlast_PDB
68.27
27%
-101
- C2 -
4MGR
3
GABR_BACSU
A:
[38-465]
------------------------------------
K
V
P
S
K
R
E
L
A
E
N
L
K
V
S
V
N
S
V
N
S
A
Y
Q
Q
L
L
A
E
G
Y
L
Y
A
I
E
R
K
G
F
F
V
----------------
E
E
L
D
M
F
S
A
E
-----------
E
H
P
P
F
ALPDDLKE
I
H
I
D
Q
S
D
W
I
S
F
S
H
M
S
S
D
T
D
H
F
P
I
K
S
W
F
R
C
E
Q
K
--
A
A
S
---
R
S
Y
R
T
L
G
D
M
S
H
P
Q
G
I
Y
E
V
R
A
A
I
T
R
L
I
S
L
T
----
R
-
G
-
V
K
-
C
R
----
P
E
Q
M
I
I
G
A
G
T
Q
V
L
M
Q
L
L
T
E
L
-
L
P
--
K
E
A
V
Y
A
M
E
E
P
G
Y
R
R
M
Y
Q
L
L
K
N
A
G
K
Q
V
K
T
I
M
L
D
E
K
G
M
S
I
A
E
I
T
R
-------------------------
Q
Q
P
D
V
L
V
T
T
P
S
H
Q
F
P
S
G
T
I
M
P
V
S
R
R
I
Q
L
L
N
W
A
A
E
E
P
-
R
-
R
Y
I
I
E
D
D
Y
D
S
E
F
T
-
Y
D
V
D
-
S
I
-
P
A
L
Q
S
L
D
---
R
F
Q
N
-----
V
I
Y
M
G
T
F
S
K
S
L
L
P
G
L
R
I
S
Y
M
V
L
-
P
P
E
L
---
L
R
A
Y
K
Q
R
G
Y
D
L
Q
T
C
S
S
L
T
Q
-
L
T
L
Q
E
F
I
E
S
---
G
E
Y
Q
-
K
-
H
I
K
K
M
K
Q
H
Y
K
E
K
R
E
R
L
I
T
A
L
E
A
E
---
F
S
--
G
-
E
V
-
T
V
K
G
A
N
A
G
L
---
H
F
V
T
E
F
D
T
R
R
T
E
Q
D
-
I
L
S
-
H
A
A
G
L
Q
L
E
I
F
G
M
S
R
F
N
L
K
E
N
K
R
Q
T
GR
P
A
L
I
I
G
F
A
R
L
K
E
E
D
I
Q
E
G
V
Q
R
L
F
----
8
PsiBlast_PDB
65.97
27%
-101
- C2 -
4N0B
2
GABR_BACSU
A:
[38-465]
------------------------------------
K
V
P
S
K
R
E
L
A
E
N
L
K
V
S
V
N
S
V
N
S
A
Y
Q
Q
L
L
A
E
G
Y
L
Y
A
I
E
R
K
G
F
F
V
----------------
E
E
L
D
M
F
S
A
E
-----------
E
H
P
P
F
ALPDDLKEIHIDQS
D
W
I
S
F
S
H
M
S
S
D
T
D
H
F
P
I
K
S
W
F
R
C
E
Q
K
--
A
A
S
---
R
S
Y
R
T
L
G
D
M
S
H
P
Q
G
I
Y
E
V
R
A
A
I
T
R
L
I
S
L
T
----
R
-
G
-
V
K
-
C
R
----
P
E
Q
M
I
I
G
A
G
T
Q
V
L
M
Q
L
L
T
E
L
-
L
P
--
K
E
A
V
Y
A
M
E
E
P
G
Y
R
R
M
Y
Q
L
L
K
N
A
G
K
Q
V
K
T
I
M
L
D
E
K
G
M
S
I
A
E
I
T
R
-------------------------
Q
Q
P
D
V
L
V
T
T
P
S
H
Q
F
P
S
G
T
I
M
P
V
S
R
R
I
Q
L
L
N
W
A
A
E
E
P
-
R
-
R
Y
I
I
E
D
D
Y
D
S
E
F
T
-
Y
D
V
D
-
S
I
-
P
A
L
Q
S
L
D
---
R
F
Q
N
-----
V
I
Y
M
G
T
F
S
K
S
L
L
P
G
L
R
I
S
Y
M
V
L
-
P
P
E
L
---
L
R
A
Y
K
Q
R
G
Y
D
L
Q
T
C
S
S
L
T
Q
-
L
T
L
Q
E
F
I
E
S
---
G
E
Y
Q
-
K
-
H
I
K
K
M
K
Q
H
Y
K
E
K
R
E
R
L
I
T
A
L
E
A
E
---
F
S
--
G
-
E
V
-
T
V
K
G
A
N
A
G
L
---
H
F
V
T
E
F
D
T
R
R
T
E
Q
D
-
I
L
S
-
H
A
A
G
L
Q
L
E
I
F
G
M
S
R
F
N
L
K
E
----
T
GR
P
A
L
I
I
G
F
A
R
L
K
E
E
D
I
Q
E
G
V
Q
R
L
F
----
38
HHSearch
65.44
27%
-113
- C2 -
3AOW
4
?
A:
[75-442]
-------------------------------------------------------------------------------------------------------------------
T
S
----------------
D
I
I
S
L
A
G
G
L
P
N
P
K
T
F
P
K
E
I
I
R
D
I
L
V
E
--
I
M
E
---
K
Y
A
D
K
A
L
Q
Y
G
T
T
K
G
F
T
P
L
R
E
T
L
M
K
W
L
G
-
K
R
---
Y
-
G
-
I
S
-
Q
-----
D
N
D
I
M
I
T
S
G
S
Q
Q
A
L
D
L
I
G
R
V
F
L
-
N
P
G
D
I
V
-
V
V
E
A
P
T
Y
L
A
A
L
Q
A
F
N
F
Y
E
P
Q
Y
I
Q
I
P
L
D
D
E
G
M
K
V
E
I
L
E
E
K
L
-----
K
-----
E
L
K
S
Q
G------
K
K
V
K
V
V
Y
T
V
P
T
F
Q
N
P
A
G
V
T
M
N
-
E
D
R
R
K
Y
L
L
E
L
A
S
E
Y
-
D
-
F
I
V
V
E
D
D
P
Y
G
E
L
R
-
Y
S
G
N
P
E
K
-
K
-
I
K
A
L
D
---
N
E
G
R
-----
V
I
Y
L
G
T
F
S
K
I
L
A
P
G
F
R
I
G
W
M
V
G
-
D
P
G
I
I
R
K
M
E
I
A
K
Q
S
T
-
D
L
C
-
T
N
V
F
G
Q
-
V
V
A
W
R
Y
V
D
G
---
G
Y
L
E
-
K
-
H
I
P
E
I
R
K
F
Y
K
P
R
R
D
A
M
L
E
A
L
E
E
--
F
M
P
E
--
G
--
V
-
K
W
T
K
-
P
E
G
G
M
F
I
W
V
T
L
P
D
G
I
D
S
K
K
M
L
-
E
R
A
-
I
K
K
G
V
A
Y
V
--
P
G
E
A
F
Y
A
H
R
D
-
V
K
N
---
T
M
R
L
N
F
T
Y
V
D
E
D
K
I
M
E
G
I
K
R
L
A
E
T
I
-
9
PsiBlast_PDB
65.41
25%
-116
- C2 -
1WST
1
?
A:
[44-404]
---------------------------------------------------------------------------------------------------------------------------------------
I
S
L
A
G
G
L
P
A
P
E
T
F
P
V
E
T
I
K
K
I
A
V
E
--
V
L
E
---
E
H
A
D
K
A
L
Q
Y
G
T
T
K
G
F
T
P
L
R
L
A
L
A
R
W
M
E
-
K
----
R
Y
D
-
I
P
-
M
S
----
K
V
E
I
M
T
V
A
G
S
Q
Q
A
L
D
L
I
G
R
V
-
F
L
N
P
G
D
P
I
-
V
V
E
A
P
T
Y
L
A
A
I
Q
A
F
K
Y
Y
D
P
E
F
I
S
I
P
L
D
D
K
G
M
R
V
D
L
L
E
E
K
L
E
E
L
R
K
Q
-----
G
-----------
K
R
V
K
I
V
Y
T
V
S
T
F
Q
N
P
A
G
V
T
M
S
-
V
D
R
R
K
K
L
L
E
L
A
N
E
Y
-
D
-
F
L
I
V
E
D
G
P
Y
S
E
L
R
Y
S
G
E
P
-
T
P
-
P
-
I
K
H
F
D
---
D
Y
G
R
-----
V
I
Y
L
G
T
F
S
K
I
L
A
P
G
F
R
I
G
W
V
A
A
-
H
P
H
L
I
R
K
M
E
I
A
K
Q
S
I
-
D
L
C
-
T
N
T
F
G
Q
-
A
I
A
W
K
Y
V
E
N
---
G
Y
L
D
-
E
-
H
I
P
K
I
I
E
F
Y
K
P
R
R
D
A
M
L
E
A
L
E
E
Y
M
P
E
G
V
----
E
W
-
T
K
P
E
G
---
G
M
F
V
R
V
T
L
P
E
G
I
D
T
K
L
M
M
-
E
R
A
-
V
A
K
G
V
A
Y
---
V
P
G
E
A
F
F
V
H
R
D
K
K
N
---
T
M
R
L
N
F
T
Y
V
P
E
E
T
I
R
E
G
V
R
R
L
-----
2
PsiBlast_PDB
64.16
27%
-110
- C2 -
3AOV
2
?
A:
[79-438]
---------------------------------------------------------------------------------------------------------------------------------------
I
S
L
A
G
G
L
P
N
P
K
T
F
P
K
E
I
I
R
D
I
L
V
E
--
I
M
E
---
K
Y
A
D
K
A
L
Q
Y
G
T
T
K
G
F
T
P
L
R
E
T
L
M
K
W
L
G
-
K
----
R
-
Y
-
G
I
-
S
Q
----
D
N
D
I
M
I
T
S
G
S
Q
Q
A
L
D
L
I
G
R
V
-
F
L
N
P
G
D
I
V
-
V
V
E
A
P
T
Y
L
A
A
L
Q
A
F
N
F
Y
E
P
Q
Y
I
Q
I
P
L
D
D
E
G
M
K
V
E
I
L
E
E
K
L
K
E
L
K
S
Q
-----
G
-----------
K
K
V
K
V
V
Y
T
V
P
T
F
Q
N
P
A
G
V
T
M
N
-
E
D
R
R
K
Y
L
L
E
L
A
S
E
Y
-
D
-
F
I
V
V
E
D
D
P
Y
G
E
L
R
-
Y
S
G
N
-
P
E
K
K
-
I
K
A
L
D
---
N
E
G
R
-----
V
I
Y
L
G
T
F
S
K
I
L
A
P
G
F
R
I
G
W
M
V
G
-
D
P
G
I
I
R
K
M
E
I
A
K
Q
S
T
-
D
L
C
-
T
N
V
F
G
Q
-
V
V
A
W
R
Y
V
D
G
---
G
Y
L
E
-
K
-
H
I
P
E
I
R
K
F
Y
K
P
R
R
D
A
M
L
E
A
L
E
E
F
M
P
E
G
V
----
K
W
-
T
K
P
E
G
---
G
M
F
I
W
V
T
L
P
D
G
I
D
S
K
K
M
L
-
E
R
A
-
I
K
K
G
V
A
Y
V
--
P
G
E
A
F
Y
A
H
R
D
V
K
-
N
---
T
M
R
L
N
F
T
Y
V
D
E
D
K
I
M
E
G
I
K
R
L
-----
5
PsiBlast_PDB
64.13
27%
-113
- C2 -
3AV7
5
?
A:
[79-438]
---------------------------------------------------------------------------------------------------------------------------------------
I
S
L
A
G
G
L
P
N
P
K
T
F
P
K
E
I
I
R
D
I
L
V
E
--
I
M
E
---
K
Y
A
D
K
A
L
Q
Y
G
T
T
K
G
F
T
P
L
R
E
T
L
M
K
W
L
G
-
K
----
R
-
Y
-
G
I
-
S
Q
----
D
N
D
I
M
I
T
S
G
S
Q
Q
A
L
D
L
I
G
R
V
-
F
L
N
P
G
D
I
V
-
V
V
E
A
P
T
Y
L
A
A
L
Q
A
F
N
F
Y
E
P
Q
Y
I
Q
I
P
L
D
D
E
G
M
K
V
E
I
L
E
E
K
L
K
E
L
K
S
Q
-----
G
-----------
K
K
V
K
V
V
Y
T
V
P
T
F
Q
N
P
A
G
V
T
M
N
-
E
D
R
R
K
Y
L
L
E
L
A
S
E
Y
-
D
-
F
I
V
V
E
D
D
P
Y
G
E
L
R
-
Y
S
G
N
-
P
E
K
K
-
I
K
A
L
D
---
N
E
G
R
-----
V
I
Y
L
G
T
F
S
K
I
L
A
P
G
F
R
I
G
W
M
V
G
-
D
P
G
I
I
R
K
M
E
I
A
K
Q
S
T
-
D
L
C
-
T
N
V
F
G
Q
-
V
V
A
W
R
Y
V
D
G
---
G
Y
L
E
-
K
-
H
I
P
E
I
R
K
F
Y
K
P
R
R
D
A
M
L
E
A
L
E
E
F
M
P
E
G
V
----
K
W
-
T
K
P
E
G
---
G
M
F
I
W
V
T
L
P
D
G
I
D
S
K
K
M
L
-
E
R
A
-
I
K
K
G
V
A
Y
V
--
P
G
E
A
F
Y
A
H
R
D
V
K
-
N
---
T
M
R
L
N
F
T
Y
V
D
E
D
K
I
M
E
G
I
K
R
L
-----
3
PsiBlast_PDB
64.07
27%
-110
- C2 -
3AOW
4
?
A:
[79-438]
---------------------------------------------------------------------------------------------------------------------------------------
I
S
L
A
G
G
L
P
N
P
K
T
F
P
K
E
I
I
R
D
I
L
V
E
--
I
M
E
---
K
Y
A
D
K
A
L
Q
Y
G
T
T
K
G
F
T
P
L
R
E
T
L
M
K
W
L
G
-
K
----
R
-
Y
-
G
I
-
S
Q
----
D
N
D
I
M
I
T
S
G
S
Q
Q
A
L
D
L
I
G
R
V
-
F
L
N
P
G
D
I
V
-
V
V
E
A
P
T
Y
L
A
A
L
Q
A
F
N
F
Y
E
P
Q
Y
I
Q
I
P
L
D
D
E
G
M
K
V
E
I
L
E
E
K
L
K
E
L
K
S
Q
-----
G
-----------
K
K
V
K
V
V
Y
T
V
P
T
F
Q
N
P
A
G
V
T
M
N
-
E
D
R
R
K
Y
L
L
E
L
A
S
E
Y
-
D
-
F
I
V
V
E
D
D
P
Y
G
E
L
R
-
Y
S
G
N
-
P
E
K
K
-
I
K
A
L
D
---
N
E
G
R
-----
V
I
Y
L
G
T
F
S
K
I
L
A
P
G
F
R
I
G
W
M
V
G
-
D
P
G
I
I
R
K
M
E
I
A
K
Q
S
T
-
D
L
C
-
T
N
V
F
G
Q
-
V
V
A
W
R
Y
V
D
G
---
G
Y
L
E
-
K
-
H
I
P
E
I
R
K
F
Y
K
P
R
R
D
A
M
L
E
A
L
E
E
F
M
P
E
G
V
----
K
W
-
T
K
P
E
G
---
G
M
F
I
W
V
T
L
P
D
G
I
D
S
K
K
M
L
-
E
R
A
-
I
K
K
G
V
A
Y
V
--
P
G
E
A
F
Y
A
H
R
D
V
K
-
N
---
T
M
R
L
N
F
T
Y
V
D
E
D
K
I
M
E
G
I
K
R
L
-----
35
HHSearch
63.96
24%
-118
- C2 -
5EFS
-
AADAT_HUMAN
A:
[30-421]
-------------------------------------------------------------------------------------------------------------------
P
K
----------------
S
M
I
S
L
A
G
G
L
P
N
P
N
M
F
P
F
K
T
A
V
I
T
V
E
N
G
K
T
I
Q
F
G
E
E
M
M
K
R
A
L
Q
Y
S
P
S
A
G
I
P
E
L
L
S
W
L
K
Q
L
Q
I
-
K
L
HNP
P
-
T
-
I
H
-
Y
P
PSQG
Q
M
D
L
C
V
T
S
G
S
Q
Q
G
L
C
K
V
F
E
M
I
I
-
N
P
G
D
N
V
-
L
L
D
E
P
A
Y
S
G
T
L
Q
S
L
H
P
L
G
C
N
I
I
N
V
A
S
D
E
S
G
I
V
P
D
S
L
R
D
I
L
-----
S
-----
R
WKPEDAKNPQK
N
T
P
K
F
L
Y
T
V
P
N
G
N
N
P
T
G
N
S
L
T
-
S
E
R
K
K
E
I
Y
E
L
A
R
K
Y
-
D
-
F
L
I
I
E
D
D
P
Y
Y
F
L
Q
-
F
N
K
F
R
V
P
-
T
-
F
L
S
M
D
---
V
D
G
R
-----
V
I
R
A
D
S
F
S
K
I
I
S
S
G
L
R
I
G
F
L
T
G
-
P
K
P
L
I
E
R
V
I
L
H
I
Q
V
S
-
T
L
H
-
P
S
T
F
N
Q
-
L
M
I
S
Q
L
L
H
E
W
G
E
E
G
F
M
-
A
-
H
V
D
R
V
I
D
F
Y
S
N
Q
K
D
A
I
L
A
A
A
D
K
--
W
L
T
---
G
--
L
A
E
W
H
V
-
P
A
A
G
M
F
L
W
I
K
V
K
G
I
N
D
V
K
E
L
I
E
E
K
A
-
V
K
M
G
V
L
M
L
--
P
G
N
A
F
Y
V
D
S
S
A
P
S
P
---
Y
L
R
A
S
F
S
S
A
S
P
E
Q
M
D
V
A
F
Q
V
L
A
Q
L
I
-
6
PsiBlast_PDB
63.95
27%
-112
- C2 -
3WX9
7
?
A:
[79-438]
---------------------------------------------------------------------------------------------------------------------------------------
I
S
L
A
G
G
L
P
N
P
K
T
F
P
K
E
I
I
R
D
I
L
V
E
--
I
M
E
---
K
Y
A
D
K
A
L
Q
Y
G
T
T
K
G
F
T
P
L
R
E
T
L
M
K
W
L
G
-
K
----
R
-
Y
-
G
I
-
S
Q
----
D
N
D
I
M
I
T
S
G
S
Q
Q
A
L
D
L
I
G
R
V
-
F
L
N
P
G
D
I
V
-
V
V
E
A
P
T
Y
L
A
A
L
Q
A
F
N
F
Y
E
P
Q
Y
I
Q
I
P
L
D
D
E
G
M
K
V
E
I
L
E
E
K
L
K
E
L
K
S
Q
-----
G
-----------
K
K
V
K
V
V
Y
T
V
P
T
F
Q
N
P
A
G
V
T
M
N
-
E
D
R
R
K
Y
L
L
E
L
A
S
E
Y
-
D
-
F
I
V
V
E
D
D
P
Y
G
E
L
R
-
Y
S
G
N
-
P
E
K
K
-
I
K
A
L
D
---
N
E
G
R
-----
V
I
Y
L
G
T
F
S
K
I
L
A
P
G
F
R
I
G
W
M
V
G
-
D
P
G
I
I
R
K
M
E
I
A
K
Q
S
T
-
D
L
C
-
T
N
V
F
G
Q
-
V
V
A
W
R
Y
V
D
G
---
G
Y
L
E
-
K
-
H
I
P
E
I
R
K
F
Y
K
P
R
R
D
A
M
L
E
A
L
E
E
F
M
P
E
G
V
----
K
W
-
T
K
P
E
G
---
G
M
F
I
W
V
T
L
P
D
G
I
D
S
K
K
M
L
-
E
R
A
-
I
K
K
G
V
A
Y
V
--
P
G
E
A
F
Y
A
H
R
D
V
K
-
N
---
T
M
R
L
N
F
T
Y
V
D
E
D
K
I
M
E
G
I
K
R
L
-----
1
PsiBlast_PDB
63.68
27%
-114
- C2 -
1X0M
-
?
A:
[59-418]
---------------------------------------------------------------------------------------------------------------------------------------
I
S
L
A
G
G
L
P
N
P
K
T
F
P
K
E
I
I
R
D
I
L
V
E
--
I
M
E
---
K
Y
A
D
K
A
L
Q
Y
G
T
T
K
G
F
T
P
L
R
E
T
L
M
K
W
L
G
-
K
----
R
-
Y
-
G
I
-
S
Q
----
D
N
D
I
M
I
T
S
G
S
Q
Q
A
L
D
L
I
G
R
V
-
F
L
N
P
G
D
I
V
-
V
V
E
A
P
T
Y
L
A
A
L
Q
A
F
N
F
Y
E
P
Q
Y
I
Q
I
P
L
D
D
E
G
M
K
V
E
I
L
E
E
K
L
K
E
L
K
S
Q
-----
G
-----------
K
K
V
K
V
V
Y
T
V
P
T
F
Q
N
P
A
G
V
T
M
N
-
E
D
R
R
K
Y
L
L
E
L
A
S
E
Y
-
D
-
F
I
V
V
E
D
D
P
Y
G
E
L
R
-
Y
S
G
N
-
P
E
K
K
-
I
K
A
L
D
---
N
E
G
R
-----
V
I
Y
L
G
T
F
S
K
I
L
A
P
G
F
R
I
G
W
M
V
G
-
D
P
G
I
I
R
K
M
E
I
A
K
Q
S
T
-
D
L
C
-
T
N
V
F
G
Q
-
V
V
A
W
R
Y
V
D
G
---
G
Y
L
E
-
K
-
H
I
P
E
I
R
K
F
Y
K
P
R
R
D
A
M
L
E
A
L
E
E
F
M
P
E
G
V
----
K
W
-
T
K
P
E
G
---
G
M
F
I
W
V
T
L
P
D
G
I
D
S
K
K
M
L
-
E
R
A
-
I
K
K
G
V
A
Y
V
--
P
G
E
A
F
Y
A
H
R
D
V
K
-
N
---
T
M
R
L
N
F
T
Y
V
D
E
D
K
I
M
E
G
I
K
R
L
-----
4
PsiBlast_PDB
63.21
27%
-109
- C2 -
3ATH
5
?
A:
[79-438]
---------------------------------------------------------------------------------------------------------------------------------------
I
S
L
A
G
G
L
P
N
P
K
T
F
P
K
E
I
I
R
D
I
L
V
E
--
I
M
E
---
K
Y
A
D
K
A
L
Q
Y
G
T
T
K
G
F
T
P
L
R
E
T
L
M
K
W
L
G
-
K
----
R
-
Y
-
G
I
-
S
Q
----
D
N
D
I
M
I
T
S
G
S
Q
Q
A
L
D
L
I
G
R
V
-
F
L
N
P
G
D
I
V
-
V
V
E
A
P
T
Y
L
A
A
L
Q
A
F
N
F
Y
E
P
Q
Y
I
Q
I
P
L
D
D
E
G
M
K
V
E
I
L
E
E
K
L
K
E
L
K
S
Q
-----
G
-----------
K
K
V
K
V
V
Y
T
V
P
T
F
Q
N
P
A
G
V
T
M
N
-
E
D
R
R
K
Y
L
L
E
L
A
S
E
Y
-
D
-
F
I
V
V
E
D
D
P
Y
G
E
L
R
-
Y
S
G
N
-
P
E
K
K
-
I
K
A
L
D
---
N
E
G
R
-----
V
I
Y
L
G
T
F
S
K
I
L
A
P
G
F
R
I
G
W
M
V
G
-
D
P
G
I
I
R
K
M
E
I
A
K
Q
S
T
-
D
L
C
-
T
N
V
F
G
Q
-
V
V
A
W
R
Y
V
D
G
---
G
Y
L
E
-
K
-
H
I
P
E
I
R
K
F
Y
K
P
R
R
D
A
M
L
E
A
L
E
E
F
M
P
E
G
V
----
K
W
-
T
K
P
E
G
---
G
M
F
I
W
V
T
L
P
D
G
I
D
S
K
K
M
L
-
E
R
A
-
I
K
K
G
V
A
Y
V
--
P
G
E
A
F
Y
A
H
R
D
V
K
-
N
---
T
M
R
L
N
F
T
Y
V
D
E
D
K
I
M
E
G
I
K
R
L
-----
43
HHSearch
62.29
24%
-113
- C2 -
2ZC0
4
?
A:
[33-401]
-------------------------------------------------------------------------------------------------------------------
G
V
----------------
K
L
I
S
L
A
A
G
D
P
D
P
E
L
I
P
R
A
V
L
G
E
I
A
K
E
--
V
L
E
---
K
E
-
P
K
S
V
M
Y
T
P
A
N
G
I
P
E
L
R
E
E
L
A
A
F
L
K
-
K
Y---
D
-
H
-
L
E
-
V
S
----
P
E
N
I
V
I
T
I
G
G
T
G
A
L
D
L
L
G
R
V
L
I
-
D
P
G
D
V
V
-
I
T
E
N
P
S
Y
I
N
T
L
L
A
F
E
Q
L
G
A
K
I
E
G
V
P
V
D
N
D
G
M
R
V
D
L
L
E
E
K
I
-----
K
-----
E
L
K
A
K
G------
Q
K
V
K
L
I
Y
T
I
P
T
G
Q
N
P
M
G
V
T
M
S
-
M
E
R
R
K
A
L
L
E
I
A
S
K
Y
-
D
-
L
L
I
I
E
D
T
A
Y
N
F
M
R
-
Y
E
G
G
D
I
V
-
P
-
L
K
A
L
D
---
N
E
G
R
-----
V
I
V
A
G
T
L
S
K
V
L
G
T
G
F
R
I
G
W
I
I
A
-
E
G
E
I
L
K
K
V
L
M
Q
K
Q
P
I
-
D
F
C
-
A
P
A
I
S
Q
-
Y
I
A
L
E
Y
L
K
R
---
G
Y
F
E
K
Y
-
H
L
E
G
A
L
L
G
Y
K
E
K
R
D
I
M
L
K
A
L
E
N
--
H
L
P
---
N
--
A
-
E
F
T
K
-
P
I
A
G
M
F
V
M
F
F
L
P
E
G
A
D
G
I
S
F
A
-
N
E
L
M
E
R
E
G
V
V
V
V
--
P
G
K
P
F
Y
T
D
E
S
-
G
K
N
---
A
I
R
L
N
F
S
R
P
S
K
E
E
I
P
I
G
I
K
K
L
A
K
L
Y
-
15
PsiBlast_PDB
61.99
25%
-107
- C2 -
2ZC0
4
?
A:
[37-397]
---------------------------------------------------------------------------------------------------------------------------------------
I
S
L
A
A
G
D
P
D
P
E
L
I
P
R
A
V
L
G
E
I
A
K
E
--
V
L
E
---
K
E
P
K
S
V
-
M
Y
T
P
A
N
G
I
P
E
L
R
E
E
L
A
A
F
L
K
-
K
Y---
D
-
H
-
L
E
-
V
S
----
P
E
N
I
V
I
T
I
G
G
T
G
A
L
D
L
L
G
R
V
L
I
D
P
G
-
D
V
V
-
I
T
E
N
P
S
Y
I
N
T
L
L
A
F
E
Q
L
G
A
K
I
E
G
V
P
V
D
N
D
G
M
R
V
D
L
L
E
E
K
I
-----
K
E
L
K
A
K
G
-----------
Q
K
V
K
L
I
Y
T
I
P
T
G
Q
N
P
M
G
V
T
M
S
-
M
E
R
R
K
A
L
L
E
I
A
S
K
Y
-
D
-
L
L
I
I
E
D
T
A
Y
N
F
M
R
Y
E
G
G
D
-
I
V
-
P
-
L
K
A
L
D
---
N
E
G
R
-----
V
I
V
A
G
T
L
S
K
V
L
G
T
G
F
R
I
G
W
I
I
A
-
E
G
E
I
L
K
K
V
L
M
Q
K
Q
P
I
-
D
F
C
-
A
P
A
I
S
Q
Y
I
A
L
E
-
Y
L
K
R
---
G
Y
F
E
-
K
Y
H
L
E
G
A
L
L
G
Y
K
E
K
R
D
I
M
L
K
A
L
E
N
H
--
L
P
N
--
A
-
E
F
-
T
---
K
P
I
A
G
M
F
V
M
F
F
L
P
E
G
A
D
G
I
S
F
A
-
N
E
L
M
E
R
E
G
V
V
V
---
V
P
G
K
P
F
Y
T
D
E
S
G
K
N
---
A
I
R
L
N
F
S
R
P
S
K
E
E
I
P
I
G
I
K
K
L
-----
44
HHSearch
60.25
24%
-116
- C2 -
2ZYJ
2
LYSN_THET2
A:
[31-390]
-------------------------------------------------------------------------------------------------------------------
R
P
----------------
G
I
L
S
F
A
G
G
L
P
A
P
E
L
F
P
K
E
E
A
A
E
A
A
A
R
--
I
L
R
---
E
K
G
E
V
A
L
Q
Y
S
P
T
E
G
Y
A
P
L
R
A
F
V
A
E
W
I
---------
G
----
V
R
----
P
E
E
V
L
I
T
T
G
S
Q
Q
A
L
D
L
V
G
K
V
F
L
-
D
E
G
S
P
V
-
L
L
E
A
P
S
Y
M
G
A
I
Q
A
F
R
L
Q
G
P
R
F
L
T
V
P
A
G
E
E
G
P
D
L
D
A
L
E
E
V
L
-----
K
-----
R
-----------
E
R
P
R
F
L
Y
L
I
P
S
F
Q
N
P
T
G
G
L
T
P
-
L
P
A
R
K
R
L
L
Q
M
V
M
E
R
-
G
-
L
V
V
V
E
D
D
A
Y
R
E
L
Y
-
F
G
E
A
R
L
P
-
S
-
L
F
E
L
A
R
E
A
G
Y
P
G
-----
V
I
Y
L
G
S
F
S
K
V
L
S
P
G
L
R
V
A
F
A
V
A
-
H
P
E
A
L
Q
K
L
V
Q
A
K
Q
G
A
-
D
L
H
-
T
P
M
L
N
Q
-
M
L
V
H
E
L
L
K
E
---
G
-
F
S
-
E
-
R
L
E
R
V
R
R
V
Y
R
E
K
A
Q
A
M
L
H
A
L
D
R
--
E
V
P
K
--
E
--
V
-
R
Y
T
R
-
P
K
G
G
M
F
V
W
M
E
L
P
K
G
L
S
A
E
G
L
F
-
R
R
A
-
L
E
E
N
V
A
F
V
--
P
G
G
P
F
F
A
N
G
G
-
G
E
N
---
T
L
R
L
S
Y
A
T
L
D
R
E
G
I
A
E
G
V
R
R
L
G
R
A
L
-
37
HHSearch
59.97
23%
-123
* C2 *
1VP4
16
?
A:
[42-415]
-------------------------------------------------------------------------------------------------------------------
D
K
----------------
D
A
I
S
F
G
G
G
V
P
D
P
E
T
F
P
R
K
E
L
A
E
I
A
K
E
--
I
I
E
---
K
E
Y
H
Y
T
L
Q
Y
S
T
T
E
G
D
P
V
L
K
Q
Q
I
L
K
L
L
E
-
R
M
---
Y
-
G
-
I
T
G
L
D
----
E
D
N
L
I
F
T
V
G
S
Q
Q
A
L
D
L
I
G
K
L
F
L
-
D
D
E
S
Y
C
-
V
L
D
D
P
A
Y
L
G
A
I
N
A
F
R
Q
Y
L
A
N
F
V
V
V
P
L
E
D
D
G
M
D
L
N
V
L
E
R
K
L
-----
S
-----
E
F
D
K
N
GKI----
K
Q
V
K
F
I
Y
V
V
S
N
F
H
N
P
A
G
V
T
T
S
-
L
E
K
R
K
A
L
V
E
I
A
E
K
Y
-
D
-
L
F
I
V
E
D
D
P
Y
G
A
L
R
-
Y
E
G
E
T
V
D
-
P
-
I
F
K
I
G
---
G
P
E
R
-----
V
V
L
L
N
T
F
S
K
V
L
A
P
G
L
R
I
G
M
V
A
G
-
S
K
E
F
I
R
K
I
V
Q
A
K
Q
S
A
-
D
L
C
-
S
P
A
I
T
H
-
R
L
A
A
R
Y
L
E
R
---
Y
D
L
L
-
E
-
Q
L
K
P
T
I
E
L
Y
R
R
K
R
T
V
M
L
N
A
L
E
E
--
Y
F
S
D
IP
G
--
V
-
K
W
V
K
-
S
E
G
G
L
F
I
W
L
T
L
P
E
G
F
D
T
W
E
M
F
-
E
Y
A
-
K
R
K
K
V
F
Y
V
--
P
G
R
V
F
K
V
Y
D
E
-
P
S
P
---
S
M
R
L
S
F
C
L
P
P
D
E
K
I
V
E
G
I
K
R
L
R
E
V
V
-
12
PsiBlast_PDB
59.93
26%
-109
- C2 -
3CBF
2
LYSN_THET2
A:
[31-390]
-------------------------------------------------------------------------------------------------------------------
R
P
----------------
G
I
L
S
F
A
G
G
L
P
A
P
E
L
F
P
K
E
E
A
A
E
A
A
A
R
--
I
L
R
---
E
K
G
E
V
A
L
Q
Y
S
P
T
E
G
Y
A
P
L
-----
R
A
F
V
-
A
----
E
-
W
-
I
G
-
V
R
----
P
E
E
V
L
I
T
T
G
S
Q
Q
A
L
D
L
V
G
K
V
-
F
L
D
E
G
S
P
V
-
L
L
E
A
P
S
Y
M
G
A
I
Q
A
F
R
L
Q
G
P
R
F
L
T
V
P
A
G
E
E
G
P
D
L
D
A
L
E
E
V
L
-----
K
-----
R
-----------
E
R
P
R
F
L
Y
L
I
P
S
F
Q
N
P
T
G
G
L
T
P
-
L
P
A
R
K
R
L
L
Q
M
V
M
E
R
-
G
-
L
V
V
V
E
D
D
A
Y
R
E
L
Y
-
F
G
E
A
-
R
L
-
P
--
S
L
F
E
---
L
A
R
E
A
GYPG
V
I
Y
L
G
S
F
S
K
V
L
S
P
G
L
R
V
A
F
A
V
A
H
P
E
A
L
Q
K
L
V
Q
A
-
K
Q
G
A
-
D
L
H
-
T
P
M
L
N
Q
-
M
L
V
H
E
L
L
K
E
---
G
-
F
S
-
E
-
R
L
E
R
V
R
R
V
Y
R
E
K
A
Q
A
M
L
H
A
L
--
D
R
E
V
P
K
--
E
V
R
Y
-
T
R
P
K
G
---
G
M
F
V
W
M
E
L
P
K
G
L
S
A
E
G
L
F
-
R
R
A
-
L
E
E
N
V
A
F
---
V
P
G
G
P
F
F
A
N
G
G
G
E
N
---
T
L
R
L
S
Y
A
T
L
D
R
E
G
I
A
E
G
V
R
R
L
G
R
A
L
-
11
PsiBlast_PDB
59.56
26%
-111
- C2 -
2ZP7
3
LYSN_THET2
C:
[31-390]
-------------------------------------------------------------------------------------------------------------------
R
P
----------------
G
I
L
S
F
A
G
G
L
P
A
P
E
L
F
P
K
E
E
A
A
E
A
A
A
R
--
I
L
R
---
E
K
G
E
V
A
L
Q
Y
S
P
T
E
G
Y
A
P
L
-----
R
A
F
V
-
A
----
E
-
W
-
I
G
-
V
R
----
P
E
E
V
L
I
T
T
G
S
Q
Q
A
L
D
L
V
G
K
V
-
F
L
D
E
G
S
P
V
-
L
L
E
A
P
S
Y
M
G
A
I
Q
A
F
R
L
Q
G
P
R
F
L
T
V
P
A
G
E
E
G
P
D
L
D
A
L
E
E
V
L
-----
K
-----
R
-----------
E
R
P
R
F
L
Y
L
I
P
S
F
Q
N
P
T
G
G
L
T
P
-
L
P
A
R
K
R
L
L
Q
M
V
M
E
R
-
G
-
L
V
V
V
E
D
D
A
Y
R
E
L
Y
-
F
G
E
A
-
R
L
-
P
--
S
L
F
E
---
L
A
R
E
AGYPG
V
I
Y
L
G
S
F
S
K
V
L
S
P
G
L
R
V
A
F
A
V
A
H
P
E
A
L
Q
K
L
V
Q
A
-
K
Q
G
A
-
D
L
H
-
T
P
M
L
N
Q
-
M
L
V
H
E
L
L
K
E
---
G
-
F
S
-
E
-
R
L
E
R
V
R
R
V
Y
R
E
K
A
Q
A
M
L
H
A
L
--
D
R
E
V
P
K
--
E
V
R
Y
-
T
R
P
K
G
---
G
M
F
V
W
M
E
L
P
K
G
L
S
A
E
G
L
F
-
R
R
A
-
L
E
E
N
V
A
F
---
V
P
G
G
P
F
F
A
N
G
G
G
E
N
---
T
L
R
L
S
Y
A
T
L
D
R
E
G
I
A
E
G
V
R
R
L
G
R
A
L
-
13
PsiBlast_PDB
59.41
26%
-107
- C2 -
2ZYJ
2
LYSN_THET2
A:
[31-390]
-------------------------------------------------------------------------------------------------------------------
R
P
----------------
G
I
L
S
F
A
G
G
L
P
A
P
E
L
F
P
K
E
E
A
A
E
A
A
A
R
--
I
L
R
---
E
K
G
E
V
A
L
Q
Y
S
P
T
E
G
Y
A
P
L
-----
R
A
F
V
-
A
----
E
-
W
-
I
G
-
V
R
----
P
E
E
V
L
I
T
T
G
S
Q
Q
A
L
D
L
V
G
K
V
-
F
L
D
E
G
S
P
V
-
L
L
E
A
P
S
Y
M
G
A
I
Q
A
F
R
L
Q
G
P
R
F
L
T
V
P
A
G
E
E
G
P
D
L
D
A
L
E
E
V
L
-----
K
-----
R
-----------
E
R
P
R
F
L
Y
L
I
P
S
F
Q
N
P
T
G
G
L
T
P
-
L
P
A
R
K
R
L
L
Q
M
V
M
E
R
-
G
-
L
V
V
V
E
D
D
A
Y
R
E
L
Y
-
F
G
E
A
-
R
L
-
P
--
S
L
F
E
---
L
A
R
E
A
GYPG
V
I
Y
L
G
S
F
S
K
V
L
S
P
G
L
R
V
A
F
A
V
A
H
P
E
A
L
Q
K
L
V
Q
A
-
K
Q
G
A
-
D
L
H
-
T
P
M
L
N
Q
-
M
L
V
H
E
L
L
K
E
---
G
-
F
S
-
E
-
R
L
E
R
V
R
R
V
Y
R
E
K
A
Q
A
M
L
H
A
L
--
D
R
E
V
P
K
--
E
V
R
Y
-
T
R
P
K
G
---
G
M
F
V
W
M
E
L
P
K
G
L
S
A
E
G
L
F
-
R
R
A
-
L
E
E
N
V
A
F
---
V
P
G
G
P
F
F
A
N
G
G
G
E
N
---
T
L
R
L
S
Y
A
T
L
D
R
E
G
I
A
E
G
V
R
R
L
G
R
A
L
-