@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu03610: (2016-06-06 )
MKKALLALFMVVSIAALAACGAGNDNQSKDNAKDGDLWASIKKKGVLTVGTEGTYEPFTYHDKDTDKLTGYDVEVITEVAKRLGLKVDFKETQWDSMFAGLNSKRFDVVANQVGKTDREDKYDFSDKYTTSRAVVVTKKDNNDIKSEADVKGKTSAQSLTSNYNKLATNAGAKVEGVEGMAQALQMIQQGRVDMTYNDKLAVLNYLKTSGNKNVKIAFETGEPQSTYFTFRKGSGEVVDQVNKALKEMKEDGTLSKISKKWFGEDVSK
Atome Classification :
(20 SA)
.........10........20........30........40........50........60..-......70........80..---.-.....90..-......100...-....-110...-.--.-..120........130........140.......150-.--------.-------..-...160---........--------170.--.-.-....-..-180----.........190.......200-.......210-.-.-...-..-.-.220.--........230..-.....240.......250.......260......---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
K
K
A
L
L
A
L
F
M
V
V
S
I
A
A
L
A
ACGAGNDNQSKDNAKD
G
D
L
W
A
S
I
KKK
G
V
L
T
VGTEGTYEPFTYHDK-DTDKLTG
Y
D
V
E
V
I
T
E
V
A
K
RL---G-
L
K
V
DFKET
Q
-
W
D
S
M
F
AGLNS
K
R
-
F
D
V
V
-
A
N
QVGK-T--D-REDK-YDFSDKYTTS-
R
A
V
V
V
TKKDNNDIKSEADVKG-K--------
T
-------
S
A
-
Q
S
L
T
S
----
N
Y
N
K
LATN--------A--G--A-K-VE
G
V
-
E
G
-
M
------
A
Q
A
L
Q
M
I
QQGR
V
D
M
TYND
K
L
A
V
-
L
N
Y
L
KTSG---N-K-
N
V
K
-
I
A
-
F
-ET--G--EPQ
S
T
Y
F
T
F
RKGS-
G
E
V
V
D
Q
V
N
K
A
L
K
E
M
KEDG
T
L
S
K
I
S
K
K
W
FGEDVSK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
81.96
53%
-50
- C2 -
2YLN
10
?
A:
[44-281]
-------------------------------
A
I
S
G
S
L
I
E
R
I
N
N
K
G
T
V
T
V
G
T
E
G
T
Y
A
P
F
T
Y
H
D
K
-
D
-
G
K
L
T
G
Y
D
V
E
V
T
R
A
V
A
E
K
L
---
G
-
V
K
V
E
F
K
E
T
Q
-
W
D
S
M
M
A
G
L
K
A
G
R
-
F
D
V
V
-
A
N
Q
V
G
L
-
T
S
P
E
-
R
Q
A
T
-
F
D
K
S
E
P
Y
S
W
S
-
G
A
V
L
V
A
H
N
D
S
N
-
I
K
S
I
A
D
I
K
G
-
V
--------
K
-------
T
A
-
Q
S
L
T
S
----
N
Y
G
E
K
A
K
A
--------
A
--
G
--
A
-
Q
-
L
V
P
V
-
D
G
-
L
------
A
Q
S
L
T
L
I
E
Q
K
R
A
D
A
T
L
N
D
E
L
A
V
-
L
D
Y
L
K
K
N
P
---
N
-
A
-
G
V
K
-
I
V
-
W
-
S
A
--
P
AD
E
K
V
G
S
G
L
I
V
N
K
G
N
-
D
E
A
V
A
K
F
S
T
A
I
N
E
L
K
A
D
G
T
L
K
K
L
G
E
Q
F
F
G
K
D
I
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
56
HHSearch
80.44
52%
-56
- C2 -
2YLN
10
?
A:
[48-280]
-----------------------------------
S
L
I
E
R
I
N
N
K
G
T
V
T
V
G
T
E
G
T
Y
A
P
F
T
Y
H
D
K
-
D
-
G
K
L
T
G
Y
D
V
E
V
T
R
A
V
A
E
K
L
---
G
-
V
K
V
E
F
K
E
T
Q
-
W
D
S
M
M
A
G
L
K
A
G
R
-
F
D
V
V
-
A
N
Q
V
G
L
T
S
--
P
E
R
Q
A
T
-
F
D
K
S
E
P
Y
S
W
S
G
A
V
L
V
A
H
N
-
D
-
S
N
I
K
S
I
A
D
I
K
G
-
V
--------
K
-------
T
A
-
Q
S
L
T
S
----
N
Y
G
E
K
A
K
A
--------
A
--
G
--
A
-
Q
-
L
V
P
V
-
D
G
-
L
------
A
Q
S
L
T
L
I
E
Q
K
R
A
D
A
T
L
N
D
E
L
A
V
-
L
D
Y
L
K
K
N
P
---
N
A
G
-
V
K
I
-
V
W
-
S
A
P
A
--
D
--
E
K
V
G
S
G
L
I
V
N
K
G
N
-
D
E
A
V
A
K
F
S
T
A
I
N
E
L
K
A
D
G
T
L
K
K
L
G
E
Q
F
F
G
K
D
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
78.81
53%
-55
- C2 -
3ZSF
-
?
A:
[39-273]
----------------------------------
G
S
L
I
E
R
I
N
N
K
G
T
V
T
V
G
T
E
G
T
Y
A
P
F
T
Y
H
D
K
-
D
-
G
K
L
T
G
Y
D
V
E
V
T
R
A
V
A
E
K
L
---
G
-
V
K
V
E
F
K
E
T
Q
-
W
D
S
M
M
A
G
L
K
A
G
R
-
F
D
V
V
-
A
N
Q
V
G
L
-
T
S
P
E
-
R
Q
A
T
-
F
D
K
S
E
P
Y
S
W
S
-
G
A
V
L
V
A
H
N
D
S
N
-
I
K
S
I
A
D
I
K
G
-
V
--------
K
-------
T
A
-
Q
S
L
T
S
----
N
Y
G
E
K
A
K
A
--------
A
--
G
--
A
-
Q
-
L
V
P
V
-
D
G
-
L
------
A
Q
S
L
T
L
I
E
Q
K
R
A
D
A
T
L
N
D
E
L
A
V
-
L
D
Y
L
K
K
N
P
---
N
-
A
-
G
V
K
-
I
V
-
W
-
S
A
--
P
AD
E
K
V
G
S
G
L
I
V
N
K
G
N
-
D
E
A
V
A
K
F
S
T
A
I
N
E
L
K
A
D
G
T
L
K
K
L
G
E
Q
F
F
G
K
D
I
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
72.66
41%
-68
- C2 -
4ZV2
1
?
A:
[9-233]
-------------------------------------------
R
G
T
L
R
V
G
T
E
A
T
F
P
P
F
G
F
K
D
--
E
N
G
K
L
V
G
F
D
I
D
L
A
K
A
I
A
K
K
L
---
G
-
V
K
V
E
F
K
P
M
D
-
F
D
G
I
I
P
A
L
Q
S
G
K
-
I
D
V
V
I
A
G
M
T
I
T
-
E
--
E
-
R
K
K
Q
-
V
D
F
S
D
P
Y
F
E
A
-
G
Q
A
I
V
V
K
K
G
N
D
S
I
K
S
L
E
D
L
K
G
-
K
--------
K
-------
V
G
-
V
Q
L
G
S
T
S
E
Q
H
V
K
K
V
A
----------
A
--
G
--
V
-
K
-
V
K
K
F
-
D
N
-
F
------
S
E
A
F
Q
E
L
K
S
G
R
V
D
A
V
V
T
D
N
A
V
A
-
L
A
Y
V
K
Q
N
P
---
N
-
A
-
G
V
K
-
I
V
-
G
-
E
T
FS
G
--
E
P
Y
G
--
I
A
V
R
K
G
N
-
S
E
L
L
E
K
I
N
K
A
L
E
E
M
K
K
D
G
T
Y
D
K
I
Y
E
K
W
F
G
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
72.10
41%
-69
- C2 -
4ZV1
1
?
A:
[9-232]
-------------------------------------------
R
G
T
L
R
V
G
T
E
A
T
F
P
P
F
G
F
K
D
--
E
N
G
K
L
V
G
F
D
I
D
L
A
K
A
I
A
K
K
L
---
G
-
V
K
V
E
F
K
P
M
D
-
F
D
G
I
I
P
A
L
Q
S
G
K
-
I
D
V
V
I
A
G
M
T
I
T
-
E
--
E
-
R
K
K
Q
-
V
D
F
S
D
P
Y
F
E
A
-
G
Q
A
I
V
V
K
K
G
N
D
S
I
K
S
L
E
D
L
K
G
-
K
--------
K
-------
V
G
-
V
Q
L
G
S
T
S
E
Q
H
V
K
K
V
A
K
D
--------
A
--
G
--
V
-
K
-
V
K
K
F
-
D
N
-
F
------
S
E
A
F
Q
E
L
K
S
G
R
V
D
A
V
V
T
D
N
A
V
A
-
L
A
Y
V
K
Q
N
P
---
N
-
A
-
G
V
K
-
I
V
-
G
-
E
T
FS
G
--
E
P
Y
G
--
I
A
V
R
K
G
N
-
S
E
L
L
E
K
I
N
K
A
L
E
E
M
K
K
D
G
T
Y
D
K
I
Y
E
K
W
F
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
70.64
29%
-59
- C2 -
4OHN
3
?
A:
[8-249]
----------------------------------
G
D
N
W
S
K
Y
Q
S
N
K
S
I
T
I
G
F
D
S
T
F
V
P
M
G
F
A
Q
K
-
D
-
G
S
Y
A
G
F
D
I
D
L
A
T
A
V
F
E
K
Y
---
G
-
I
T
V
N
W
Q
P
I
D
-
W
D
L
K
E
A
E
L
T
K
G
T
-
I
D
L
I
-
W
N
G
Y
S
A
-
T
--
D
E
R
R
E
K
-
V
A
F
S
N
S
Y
M
K
N
-
E
Q
V
L
V
T
K
K
S
S
G
-
I
T
T
A
K
D
M
T
G
-
K
--------
T
L
------
G
A
-
Q
A
G
S
S
----
G
Y
A
D
F
E
A
N
PEILKNIV
A
--
N
--
K
-
E
-
A
N
Q
Y
-
Q
T
-
F
------
N
E
A
L
I
D
L
K
N
D
R
I
D
G
L
L
I
D
R
V
Y
A
-
N
Y
Y
L
E
A
E
G
---
V
-
L
-
N
D
Y
-
N
V
-
F
-
T
V
--
G
L-
E
T
E
A
F
A
V
G
S
R
K
E
D
-
T
T
L
V
K
K
I
N
E
A
F
S
S
L
Y
K
D
G
K
F
Q
E
I
S
Q
K
W
F
G
E
D
V
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
70.07
32%
-75
- C2 -
4C0R
28
?
A:
[5-229]
----------------------------------------------
V
T
L
A
T
V
G
T
T
N
P
F
S
Y
E
K
K
-
G
--
K
L
T
G
Y
D
I
E
V
A
K
E
V
F
K
A
S
---
D
K
Y
D
V
K
Y
Q
K
T
E
-
W
T
S
I
F
S
G
L
D
S
D
K
-
Y
Q
I
G
-
A
N
N
I
S
Y
-
T
K
-
E
-
R
A
N
K
-
Y
L
Y
S
N
P
T
A
S
N
-
P
L
V
L
V
V
P
K
D
-
S
D
I
K
S
Y
N
D
I
A
G
-
H
--------
S
T
Q
V
V
Q
GN
T
T
-
V
P
M
L
Q
----
K
F
N
K
N
H
E
N
--------
N
--
Q
--
V
-
K
-
L
N
F
T
S
E
D
-
L
------
A
H
Q
I
R
N
V
S
D
G
K
Y
D
F
K
I
F
E
K
I
S
A
-
E
T
I
I
K
E
Q
G
---
L
-
D
-
N
L
K
V
I
D
-
L
-
P
S
--
D
--
Q
K
P
Y
V
Y
F
I
F
A
Q
D
Q
-
K
D
L
Q
K
F
V
N
K
R
L
K
K
L
Y
E
N
G
T
L
E
K
L
S
K
K
Y
L
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
69.42
32%
-73
- C2 -
4C0R
11
?
B:
[5-229]
----------------------------------------------
V
T
L
A
T
V
G
T
T
N
P
F
S
Y
E
K
K
-
G
--
K
L
T
G
Y
D
I
E
V
A
K
E
V
F
K
A
S
---
D
K
Y
D
V
K
Y
Q
K
T
E
-
W
T
S
I
F
S
G
L
D
S
D
K
-
Y
Q
I
G
-
A
N
N
I
S
Y
-
T
K
-
E
-
R
A
N
K
-
Y
L
Y
S
N
P
T
A
S
N
-
P
L
V
L
V
V
P
K
D
-
S
D
I
K
S
Y
N
D
I
A
G
-
H
--------
S
T
Q
V
V
Q
GN
T
T
-
V
P
M
L
Q
----
K
F
N
K
N
H
E
N
--------
N
--
Q
--
V
-
K
-
L
N
F
T
S
E
D
-
L
------
A
H
Q
I
R
N
V
S
D
G
K
Y
D
F
K
I
F
E
K
I
S
A
-
E
T
I
I
K
E
Q
G
---
L
-
D
-
N
L
K
V
I
D
-
L
-
P
S
--
D
--
Q
K
P
Y
V
Y
F
I
F
A
Q
D
Q
-
K
D
L
Q
K
F
V
N
K
R
L
K
K
L
Y
E
N
G
T
L
E
K
L
S
K
K
Y
L
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
HHSearch
68.21
31%
-70
- C2 -
3VV5
1
?
A:
[26-257]
----------------------------------
V
R
S
F
E
E
I
K
R
S
G
E
I
R
I
G
T
E
G
A
F
P
P
F
N
Y
F
D
E
-
R
-
N
Q
L
T
G
F
E
V
D
L
G
N
A
I
A
E
R
L
---
G
-
L
K
P
R
W
I
A
Q
S
-
F
D
T
L
L
I
Q
L
N
Q
G
R
-
F
D
F
V
-
I
A
S
H
G
I
-
T
--
E
E
R
A
R
A
-
V
D
F
T
N
P
H
Y
C
T
G
G
V
I
V
S
R
K
-
G
G
--
P
R
T
A
K
D
L
Q
G
-
K
--------
V
-------
V
G
-
V
Q
V
G
T
----
T
Y
M
E
A
A
Q
K
--------
I
P-
G
--
I
K
E
-
V
R
T
Y
-
Q
R
-
D
------
P
D
A
L
Q
D
L
L
A
G
R
I
D
T
W
I
T
D
R
F
V
A
-
K
E
A
I
K
E
R
K
---
L
-
E
-
N
T
L
-
Q
V
-
G
-
E
L
--
V
--
F
Q
E
R
V
A
M
A
V
A
K
G
N
-
K
S
L
L
D
A
L
N
R
A
L
A
E
L
M
Q
D
G
T
Y
A
R
I
S
Q
K
W
F
G
E
D
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
65.87
31%
-66
- C2 -
4EQ9
1
?
A:
[7-236]
------------------------------------------
K
K
E
I
I
-
V
A
T
N
G
S
P
R
P
F
I
Y
--
E
-
E
N
G
E
L
T
G
Y
E
I
E
V
V
R
A
I
F
K
D
S
---
D
K
Y
D
V
K
F
E
K
T
E
-
W
S
G
V
F
A
G
L
D
A
D
R
-
Y
N
M
A
-
V
N
N
L
S
Y
-
T
K
-
E
-
R
A
E
K
-
Y
L
Y
A
A
P
I
A
Q
N
-
P
N
V
L
V
V
K
K
D
D
S
S
I
K
S
L
D
D
I
G
G
-
K
S
T
E
V
V
Q
AT
T
-------
S
A
-
K
Q
L
E
A
-----
Y
N
A
E
H
T
D
--------
N
--
P
--
T
-
I
-
L
N
Y
T
-
K
A
D
F
------
Q
Q
I
M
V
R
L
S
D
G
Q
F
D
Y
K
I
F
D
K
I
G
V
-
E
T
V
I
K
N
Q
G
---
L
-
D
-
N
L
K
V
I
E
-
L
-
P
S
--
D
--
Q
Q
P
Y
V
Y
P
L
L
A
Q
G
Q
-
D
E
L
K
S
F
V
D
K
R
I
K
E
L
Y
K
D
G
T
L
E
K
L
S
K
Q
F
F
G
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
65.66
30%
-65
- C2 -
3HV1
-
?
A:
[35-275]
-----------------------------------
D
Q
W
Q
T
Y
T
K
E
K
K
I
K
I
G
F
D
A
T
F
V
P
M
G
Y
E
E
K
-
D
G
S
Y
I
-
G
F
D
I
D
L
A
N
A
V
F
K
L
Y
---
G
-
I
D
V
E
W
Q
A
I
D
-
W
D
M
K
E
T
E
L
K
N
G
T
-
I
D
L
I
-
W
N
G
Y
S
V
-
T
--
D
E
R
K
Q
S
-
A
D
F
T
E
P
Y
M
V
N
-
E
Q
V
L
V
T
K
K
S
S
G
-
I
D
S
V
A
G
M
A
G
-
K
--------
T
L
------
G
A
-
Q
A
G
S
S
----
G
Y
D
A
F
N
A
S
PKILKDVV
A
--
N
--
Q
-
K
-
V
V
Q
Y
-
S
T
-
F
------
T
Q
A
L
I
D
L
N
S
G
R
I
D
G
L
L
I
D
R
V
Y
A
-
N
Y
Y
L
E
K
S
G
VLD
Q
-
Y
-
N
V
M
-
P
A
-
G
-
Y
E
--
G
--
E
--
S
F
A
V
G
A
R
K
V
D
-
K
T
L
I
K
K
I
N
Q
G
F
E
T
L
Y
K
N
G
E
F
Q
K
I
S
N
K
W
F
G
E
D
V
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
65.25
30%
-74
- C2 -
3VV5
1
?
A:
[32-257]
----------------------------------------
I
K
R
S
G
E
I
R
I
G
T
E
G
A
F
P
P
F
N
Y
F
D
--
E
R
N
Q
L
T
G
F
E
V
D
L
G
N
A
I
A
E
R
L
---
G
-
L
K
P
R
W
I
A
Q
S
-
F
D
T
L
L
I
Q
L
N
Q
G
R
-
F
D
F
V
-
I
A
S
H
G
I
-
T
--
E
E
R
A
R
A
-
V
D
F
T
N
P
H
Y
C
T
-
G
G
V
I
V
S
R
K
G
G
P
--
R
T
A
K
D
L
Q
G
-
K
--------
V
-------
V
G
-
V
Q
V
G
T
----
T
Y
----
M
E
--------
A
--
A
--
Q
-
K
-
I
P
G
I
-
K
E
-
V
R
T
Y
QR
D
P
D
A
L
Q
D
L
L
A
G
R
I
D
T
W
I
T
D
R
F
V
A
-
K
E
A
I
K
E
R
K
---
L
-
E
-
N
T
L
-
Q
V
-
G
-
E
L
--
V
--
F
Q
E
R
V
A
M
A
V
A
K
G
N
-
K
S
L
L
D
A
L
N
R
A
L
A
E
L
M
Q
D
G
T
Y
A
R
I
S
Q
K
W
F
G
E
D
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
55
HHSearch
65.19
25%
-98
- C- -
4PRS
-
?
A:
[2-226]
-------------------------------------
I
D
E
I
K
S
R
G
Y
L
L
V
G
L
S
A
D
F
P
P
F
E
F
V
D
E
-
N
-
G
N
I
V
G
F
D
V
D
L
A
K
E
I
A
R
R
L
---
G
-
V
E
L
K
I
V
D
M
T
-
F
D
G
L
I
P
S
L
L
T
K
K
-
I
D
V
I
-
I
S
G
M
T
I
-
T
--
E
E
R
K
K
V
-
V
A
F
S
D
P
Y
F
D
A
G
Q
V
I
V
V
R
K
D
S
D
F
R
P
K
T
Y
E
D
L
V
G
-
K
--------
T
-------
V
A
-
V
Q
I
G
T
----
T
G
D
I
E
V
S
K
--------
Y
D-
G
--
I
-
K
-
V
V
R
F
-
D
K
-
F
------
T
D
A
F
L
E
L
K
R
G
R
A
D
A
V
V
L
D
S
A
T
A
-
R
A
F
V
A
K
N
P
---
D
---
L
V
I
-
S
S
---
G
V
--
L
--
S
S
E
Q
Y
G
I
A
V
R
K
E
D
-
T
D
L
L
E
F
I
N
S
V
L
R
E
L
K
K
S
P
-
Y
D
V
L
I
E
K
W
F
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
HHSearch
64.53
26%
-70
- C2 -
5EYF
3
?
A:
[5-239]
----------------------------------
E
D
I
L
E
R
S
K
S
T
N
E
I
I
W
G
V
K
Y
D
T
R
L
F
G
M
M
D
I
E
S
-
R
T
V
Q
G
F
D
V
D
I
A
K
A
I
T
K
K
I
LGD
N
-
G
K
T
E
F
V
E
V
T
-
S
K
T
R
I
P
L
L
K
N
G
N
-
I
D
A
I
-
I
A
T
M
T
I
-
T
--
D
E
R
K
K
Q
-
V
D
F
S
D
V
Y
F
D
A
G
Q
A
L
L
V
K
K
-
G
-
S
Q
I
K
S
V
D
D
L
N
A
S
T
--------
T
-------
V
L
-
A
V
K
G
S
----
T
S
A
A
N
I
R
Q
--------
H
A
P
D
--
A
-
K
-
I
L
E
L
-
E
N
-
Y
------
A
E
A
F
T
A
L
Q
S
G
Q
G
D
A
M
T
T
D
N
A
I
L
-
L
G
I
A
D
E
N
P
---
E
---
Y
E
L
-
V
G
---
G
T
--
F
--
T
N
E
P
Y
G
I
A
I
N
K
G
Q
-
E
N
F
L
K
A
V
N
Q
A
L
E
E
M
H
A
D
G
T
Y
D
K
I
Y
Q
K
W
F
P
N
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
64.12
22%
-60
- C2 -
4P0G
9
MLTF_PSEAE
A:
[7-435]
---------------------------------
A
P
T
A
L
E
R
V
Q
K
E
G
V
L
R
V
I
T
R
N
S
--
P
A
T
Y
-
F
Q
-
D
R
N
G
E
T
G
F
E
Y
E
L
A
K
R
F
A
E
R
L
---
G
-
V
E
L
K
I
E
T
A
D
N
L
D
D
L
Y
A
Q
L
S
R
E
G
G
P
A
L
A
-
A
A
G
L
T
P
-
G
--
R
-
E
D
D
A
S
V
R
Y
S
H
T
Y
L
D
V
-
T
P
Q
I
I
Y
R
N
G
Q
Q
R
P
T
R
P
E
D
L
V
G
-
K
R
I
M
V
L
K
G-
S
-------
S
H
-
A
E
Q
L
A
----
E
L
K
K
Q
Y
P
E
--------
L
--
K
--
Y
-
E
-
E
S
D
A
-
V
E
-
V
------
V
D
L
L
R
M
V
D
V
G
D
I
D
L
T
L
V
D
S
N
E
L
A
M
N
Q
V
Y
F
P
--------
N
V
R
-
V
A
-
F
-
D
F
--
G
--
E
A
R
G
L
A
W
A
L
P
G
G
D
D
D
S
L
M
N
E
V
N
A
F
L
D
Q
A
K
K
E
G
L
L
Q
R
L
K
D
R
Y
Y
G
-
H
V
D
V
LG
Y
V
G
A
Y
T
F
A
Q
H
L
Q
Q
RLPRY
E
S
H
F
K
Q
S
G
K
Q
L
DTD
W
R
L
L
A
A
I
G
Y
Q
E
SLWQPGATSKTGVRGLMMLT
N
R
T
A
Q
A
M
GVSNRLD
P
K
Q
S
I
Q
G
G
S
K
Y
F
V
Q
I
R
S
E
LPESIKE
P
D
R
S
W
F
A
L
A
A
Y
N
IG
G
A
H
L
E
D
A
R
K
M
A
E
K
E
GLNPNK
W
L
D
V
K
K
M
LPRLAQKQWYAKTRYGYAR
G
G
E
T
V
H
F
V
Q
N
V
R
R
Y
Y
D
I
L
T
W
V
T
Q
P
Q
7
PsiBlast_PDB
63.84
30%
-74
- C2 -
3VVD
1
?
A:
[32-257]
----------------------------------------
I
K
R
S
G
E
I
R
I
G
T
E
G
A
F
P
P
F
N
Y
F
D
--
E
R
N
Q
L
T
G
F
E
V
D
L
G
N
A
I
A
E
R
L
---
G
-
L
K
P
R
W
I
A
Q
S
-
F
D
T
L
L
I
Q
L
N
Q
G
R
-
F
D
F
V
-
I
A
S
H
G
I
-
T
--
E
E
R
A
R
A
-
V
D
F
T
N
P
H
Y
C
T
-
G
G
V
I
V
S
R
K
G
G
P
--
R
T
A
K
D
L
Q
G
-
K
--------
V
-------
V
G
-
V
Q
V
G
T
----
T
Y
----
M
E
--------
A
--
A
--
Q
-
K
-
I
P
G
I
-
K
E
-
V
R
T
Y
QR
D
P
D
A
L
Q
D
L
L
A
G
R
I
D
T
W
I
T
D
R
F
V
A
-
K
E
A
I
K
E
R
K
---
L
-
E
-
N
T
L
-
Q
V
-
G
-
E
L
--
V
--
F
Q
E
R
V
A
M
A
V
A
K
G
N
-
K
S
L
L
D
A
L
N
R
A
L
A
E
L
M
Q
D
G
T
Y
A
R
I
S
Q
K
W
F
G
E
D
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
HHSearch
63.80
28%
-68
- C2 -
3HV1
-
?
A:
[33-273]
---------------------------------
Q
K
D
Q
W
Q
T
Y
T
K
E
K
K
I
K
I
G
F
D
A
T
F
V
P
M
G
Y
E
E
K
-
D
-
G
S
Y
I
G
F
D
I
D
L
A
N
A
V
F
K
L
Y
---
G
-
I
D
V
E
W
Q
A
I
D
-
W
D
M
K
E
T
E
L
K
N
G
T
-
I
D
L
I
-
W
N
G
Y
S
V
-
T
--
D
E
R
K
Q
S
-
A
D
F
T
E
P
Y
M
V
N
E
Q
V
L
V
T
K
K
-
S
-
S
G
I
D
S
V
A
G
M
A
G
-
K
--------
T
-------
L
G
-
A
Q
A
G
S
----
S
G
Y
D
A
F
N
A
S
PKILKD-
V
VA
N
--
Q
-
K
-
V
V
Q
Y
-
S
T
-
F
------
T
Q
A
L
I
D
L
N
S
G
R
I
D
G
L
L
I
D
R
V
Y
A
-
N
Y
Y
L
E
K
S
G
---
V
-
L
-
D
Q
Y
-
N
V
M
P
-
A
G
--
Y
--
E
G
E
S
F
A
V
G
A
R
K
V
D
-
K
T
L
I
K
K
I
N
Q
G
F
E
T
L
Y
K
N
G
E
F
Q
K
I
S
N
K
W
F
G
E
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
58
HHSearch
63.56
29%
-70
* C2 *
2PVU
3
?
A:
[38-265]
----------------------------------------
G
A
T
K
K
K
V
V
V
G
T
D
A
A
F
A
P
F
E
Y
M
Q
--
K
-
G
K
I
V
G
F
D
V
D
L
L
D
A
V
M
K
A
A
---
G
-
L
D
Y
E
L
K
N
I
G
-
W
D
P
L
F
A
S
L
Q
S
K
E
-
V
D
M
G
-
I
S
G
I
T
I
-
T
--
D
E
R
K
Q
S
-
Y
D
F
S
D
P
Y
F
E
A
T
Q
V
I
L
V
K
Q
-
G
-
S
P
V
K
N
A
L
D
L
K
G
-
K
--------
T
-------
I
G
-
V
Q
N
A
T
----
T
G
Q
E
A
A
E
K
--------
L
F-
G
KG
P
-
H
-
I
K
K
F
-
E
T
-
T
------
V
V
A
I
M
E
L
L
N
G
G
V
D
A
V
I
T
D
N
A
V
A
-
N
E
Y
V
K
N
N
P
---
N
-
K
K
L
Q
V
-
I
E
---
D
P
KN
F
--
A
S
E
Y
Y
G
M
I
F
P
K
-
N
-
S
E
L
K
A
K
V
D
E
A
L
K
N
V
I
N
S
G
K
Y
T
E
I
Y
K
K
W
F
G
K
E
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
63.46
30%
-75
- C2 -
3VVF
3
?
A:
[32-257]
----------------------------------------
I
K
R
S
G
E
I
R
I
G
T
E
G
A
F
P
P
F
N
Y
F
D
--
E
R
N
Q
L
T
G
F
E
V
D
L
G
N
A
I
A
E
R
L
---
G
-
L
K
P
R
W
I
A
Q
S
-
F
D
T
L
L
I
Q
L
N
Q
G
R
-
F
D
F
V
-
I
A
S
H
G
I
-
T
--
E
E
R
A
R
A
-
V
D
F
T
N
P
H
Y
C
T
-
G
G
V
I
V
S
R
K
G
G
P
--
R
T
A
K
D
L
Q
G
-
K
--------
V
-------
V
G
-
V
Q
V
G
T
----
T
Y
----
M
E
--------
A
--
A
--
Q
-
K
-
I
P
G
I
-
K
E
-
V
R
T
Y
QR
D
P
D
A
L
Q
D
L
L
A
G
R
I
D
T
W
I
T
D
R
F
V
A
-
K
E
A
I
K
E
R
K
---
L
-
E
-
N
T
L
-
Q
V
-
G
-
E
L
--
V
--
F
Q
E
R
V
A
M
A
V
A
K
G
N
-
K
S
L
L
D
A
L
N
R
A
L
A
E
L
M
Q
D
G
T
Y
A
R
I
S
Q
K
W
F
G
E
D
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
63.40
33%
-68
- C2 -
1GGG
-
GLNH_ECOLI
A:
[5-222]
----------------------------------------------
L
V
V
A
T
D
T
A
F
V
P
F
E
F
--
K
-
Q
G
D
L
Y
V
G
F
D
V
D
L
W
A
A
I
A
K
E
L
---
K
-
L
D
Y
E
L
K
P
M
D
-
F
S
G
I
I
P
A
L
Q
T
K
N
-
V
D
L
A
-
L
A
G
I
T
I
-
T
--
D
E
R
K
K
A
-
I
D
F
S
D
G
Y
Y
K
S
-
G
L
L
V
M
V
K
A
N
N
N
D
V
K
S
V
K
D
L
D
G
-
K
--------
V
-------
V
A
V
K
S
G
T
G
----
S
V
D
Y
A
K
A
N
--------
I
--
K
--
T
-
K
D
L
R
Q
F
-
P
N
-
I
------
D
N
A
Y
M
E
L
G
T
N
R
A
D
A
V
L
H
D
T
P
N
I
-
L
Y
F
I
K
T
A
G
---
N
-
G
-
Q
F
K
-
A
V
-
G
-
D
S
--
L
--
E
A
Q
Q
Y
G
I
A
F
P
K
G
S
-
D
E
L
R
D
K
V
N
G
A
L
K
T
L
R
E
N
G
T
Y
N
E
I
Y
K
K
W
F
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------