@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu03930: (2016-06-06 )
MYPDLKGKVVAITGAASGLGKAMAIRFGKEQAKVVINYYSNKQDPNEVKEEVIKAGGEAVVVQGDVTKEEDVKNIVQTAIKEFGTLDIMINNAGLENPVPSHEMPLKDWDKVIGTNLTGAFLGSREAIKYFVENDIKGNVINMSSVHEVIPWPLFVHYAASKGGIKLMTETLALEYAPKGIRVNNIGPGAINTPINAEKFADPKQKADVESMIPMGYIGEPEEIAAVAAWLASKEASYVTGITLFADGGMTQYPSFQAGRG
Atome Classification :
(27 SA)
.........10........20........30........40..-......50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MYPDLKG
K
V
V
A
I
TGAASGLG
K
A
M
A
IRFGKE
Q
A
K
V
V
I
N
YYSNKQ-
D
P
N
E
V
K
E
E
V
I
KAGG
E
A
V
V
V
QGDVT
K
E
E
D
V
K
N
I
V
Q
T
A
I
K
EFG
T
L
D
I
M
I
NNAGLENPVPSHEM
P
L
K
D
W
D
K
V
IGTNL
T
G
A
FLG
S
R
E
A
I
K
Y
F
V
ENDIKG
N
V
I
N
M
S
S
V
H
EVIPW
P
L
F
V
H
Y
AASKG
G
I
K
L
M
T
E
T
L
A
L
EYAPKG
I
R
VNNIGPGAINTPI
N
A
E
KFAD
P
K
Q
KA
D
V
E
S
MIPMGYIG
E
P
E
E
I
A
A
V
A
A
W
L
A
SKEA
S
Y
V
T
G
I
T
L
F
ADGGMTQYPSFQAGRG
31
PsiBlast_CBE
82.82
83%
-65
- C1 -
1G6K
1
DHG_BACME
E:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
-
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
A
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
Q
Y
P
S
F
Q
A
G
R
G
30
PsiBlast_CBE
82.43
83%
-65
- C1 -
1G6K
1
DHG_BACME
F:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
-
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
A
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
Q
Y
P
S
F
Q
A
G
R
G
7
PsiBlast_PDB
82.33
83%
-62
- C1 -
1G6K
1
DHG_BACME
A:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
-
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
A
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
Q
Y
P
S
F
Q
A
G
R
G
32
PsiBlast_CBE
82.16
83%
-62
- C1 -
1G6K
1
DHG_BACME
B:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
-
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
A
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
Q
Y
P
S
F
Q
A
G
R
G
34
PsiBlast_CBE
81.92
83%
-62
- C1 -
1GEE
1
DHG_BACME
E:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
-
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
F
Q
A
G
R
G
35
PsiBlast_CBE
81.84
83%
-61
- C1 -
1GEE
1
DHG_BACME
B:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
-
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
F
Q
A
G
R
G
27
PsiBlast_CBE
81.80
83%
-61
- C1 -
1GCO
1
DHG_BACME
F:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
-
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
Q
Y
P
S
F
Q
A
G
R
G
8
PsiBlast_PDB
81.80
83%
-61
- C1 -
1GEE
1
DHG_BACME
A:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
-
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
F
Q
A
G
R
G
126
HHSearch
81.74
83%
-60
- C1 -
1GEE
1
DHG_BACME
A:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
-
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
F
Q
A
G
R
G
4
PsiBlast_PDB
81.23
82%
-62
- C1 -
3AY7
-
DHG4_BACME
A:
[9-267]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
-
E
A
L
D
A
K
K
E
V
E
E
A
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
V
P
S
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
P
I
N
A
E
K
F
A
D
P
V
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
F
Q
A
A
--
29
PsiBlast_CBE
81.22
83%
-59
- C1 -
1GCO
1
DHG_BACME
B:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
-
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
Q
Y
P
S
F
Q
A
G
R
G
6
PsiBlast_PDB
81.22
83%
-60
- C1 -
1GCO
1
DHG_BACME
A:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
-
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
Q
Y
P
S
F
Q
A
G
R
G
33
PsiBlast_CBE
81.20
83%
-62
- C1 -
1GEE
1
DHG_BACME
F:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
-
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
F
Q
A
G
R
G
9
PsiBlast_PDB
81.11
82%
-62
- C1 -
1RWB
1
DHG_BACME
A:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
-
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
K
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
F
Q
A
G
R
G
22
PsiBlast_CBE
80.98
82%
-63
- C1 -
3AUT
1
DHG4_BACME
B:
[9-269]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
-
E
A
L
D
A
K
K
E
V
E
E
A
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
V
P
S
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
P
I
N
A
E
K
F
A
D
P
V
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
F
Q
A
G
R
G
37
PsiBlast_CBE
80.97
82%
-63
- C1 -
1RWB
1
DHG_BACME
E:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
-
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
K
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
F
Q
A
G
R
G
2
PsiBlast_PDB
80.94
82%
-63
- C1 -
3AUT
-
DHG4_BACME
A:
[9-269]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
-
E
A
L
D
A
K
K
E
V
E
E
A
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
V
P
S
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
P
I
N
A
E
K
F
A
D
P
V
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
F
Q
A
G
R
G
28
PsiBlast_CBE
80.76
83%
-61
- C1 -
1GCO
1
DHG_BACME
E:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
-
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
Q
Y
P
S
F
Q
A
G
R
G
23
PsiBlast_CBE
80.53
82%
-62
- C1 -
3AY7
1
DHG4_BACME
B:
[9-266]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
-
E
A
L
D
A
K
K
E
V
E
E
A
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
V
P
S
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
P
I
N
A
E
K
F
A
D
P
V
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
F
Q
A
---
38
PsiBlast_CBE
80.23
82%
-59
- C1 -
1RWB
1
DHG_BACME
B:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
-
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
K
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
F
Q
A
G
R
G
36
PsiBlast_CBE
80.11
82%
-62
- C1 -
1RWB
1
DHG_BACME
F:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
-
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
K
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
F
Q
A
G
R
G
25
PsiBlast_CBE
80.09
82%
-64
- C1 -
3AY6
4
DHG4_BACME
C:
[9-269]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
-
E
A
L
D
A
K
K
E
V
E
E
A
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
V
P
S
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
P
I
N
A
E
K
F
A
D
P
V
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
F
Q
F
G
R
G
5
PsiBlast_PDB
79.94
82%
-64
- C1 -
3AY6
4
DHG4_BACME
A:
[9-269]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
-
E
A
L
D
A
K
K
E
V
E
E
A
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
V
P
S
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
P
I
N
A
E
K
F
A
D
P
V
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
F
Q
F
G
R
G
3
PsiBlast_PDB
79.40
82%
-61
- C1 -
3AUU
1
DHG4_BACME
A:
[9-269]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
-
E
A
L
D
A
K
K
E
V
E
E
A
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
V
P
S
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
P
I
N
A
E
K
F
A
D
P
V
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
F
Q
A
G
R
G
26
PsiBlast_CBE
78.97
82%
-60
- C1 -
3AY6
4
DHG4_BACME
B:
[9-269]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
-
E
A
L
D
A
K
K
E
V
E
E
A
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
V
P
S
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
P
I
N
A
E
K
F
A
D
P
V
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
F
Q
F
G
R
G
21
PsiBlast_CBE
78.91
82%
-61
- C1 -
3AUU
1
DHG4_BACME
B:
[9-269]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
-
E
A
L
D
A
K
K
E
V
E
E
A
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
V
P
S
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
P
I
N
A
E
K
F
A
D
P
V
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
F
Q
A
G
R
G
24
PsiBlast_CBE
77.68
82%
-58
- C1 -
3AY6
4
DHG4_BACME
D:
[9-269]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
-
E
A
L
D
A
K
K
E
V
E
E
A
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
V
P
S
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
P
I
N
A
E
K
F
A
D
P
V
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
F
Q
F
G
R
G