@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : bsu04260: (2016-06-07 )
MSKTVVLAEKPSVGRDLARVLKCHKKGNGYLEGDQYIVTWALGHLVTLADPEGYGKEFQSWRLEDLPIIPEPLKLVVIKKTGKQFNAVKSQLTRKDVNQIVIATDAGREGELVARWIIEKANVRKPIKRLWISSVTDKAIKEGFQKLRSGKEYENLYHSAVARAEADWIVGINATRALTTKFNAQLSCGRVQTPTLAMIAKREADIQAFTPVPYYGIRAAVDGMTLTWQDKKSKQTRTFNQDVTSRLLKNLQGKQAVVAELKKTAKKSFAPALYDLTELQRDAHKRFGFSAKETLSVLQKLYEQHKLVTYPRTDSRFLSSDIVPTLKDRLEGMEVKPYAQYVSQIKKRGIKSHKGYVNDAKVSDHHAIIPTEEPLVLSSLSDKERKLYDLIAKRFLAVLMPAFEYEETKVIAEIGGETFTAKGKTVQSQGWKAVYDMAEEDDEQEDDRDQTLPALQKGDTLAVRTLTETSGQTKPPARFNEGTLLSAMENPSAFMQGEEKGLVKTLGETGGLGTVATRADIIEKLFNSFLIEKKGQDIFITSKGKQLLQLVPEDLKSPALTAEWEQKLSAIAAGKLKSAVFIKDMKAYAHQTVKEIKNSSQTFRHDNITGTACPECGKMMLKVNGKRGTMLVCQDRECGSRKTIARKTNARCPNCHKRMELRGQGEGQTFACVCGHREKLSVFEKRKNKDKARATKRDVSSYMKKQNKDEPINNALAEQLKKLGLDK

Atome Classification :

(20 SA) ------------.........10........20----...--...----..------30.------.--.-.....40........50----.........------60----..-.......70-..--......80........90.----.......100.......110.......120.----...---...130.......140.......150..-.....160.......170.......-----180.---------..---------....190.......200.......210.......220----..-----------......230-----.------------------.------......240.......250..-......260.......270-.......280.......290.......300.-------.-------.....310.......320.......330.....-..-340.......-350.......360..-.....370..---.---.-----.----..----380.......390.......400.......410..----.....420....--...430.......440..--.....450.......460.......470.......480.......490.......500.......510.......520.......530..-.....540........550.---......560.......570.......580.......----590.....-.-.-600----..--.----.-----.....610.......620.......630..-..-----...640.....------------------..650.......660-.......670.----......680.......690.......700.......710.......720.-....
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) ------------MSKTVVLAEKPSVGRDLARVL----KCH--KKG----NG------YLE------G--D-QYIVTWALGHLVTLAD-----PEGYGKEFQ------S-----WR-LEDLPIIPE-PL--KLVVIKKTGKQFNAVKSQL----TRKDVNQIVIATDAGREGELVARWIIEKANV----RKP---IKRLWISSVTDKAIKEGFQKLRSGKEYE-NLYHSAVARAEADWIVGINATRALT-----TKFN---------AQ---------LSCGRVQTPTLAMIAKREADIQAFTPVPYYGIRAAV-----DG-----------MTLTWQDK------K------------------S------KQTRTFNQDVTSRLLKNL-QG-KQAVVAELKKTAKKSFAPA-LYDLTELQRDAHKRFGFSAKETLSVLQKLYE-------Q-------HKLVTYPRTDSRFLSSDIVPTLKDRLEGMEVKP-YA-QYVSQIKKRG-IKSHKGYVNDAKVSD-HHAIIPTEEP---L---V-----L----SS----LSDKERKLYDLIAKRFLAVLMPAFEYEETKVIAEI----GGETFTAKGKTV--QSQGWKAVYDMAEEDDEQ--EDDRDQTLPALQKGDTLAVRTLTETSGQTKPPARFNEGTLLSAMENPSAFMQGEEKGLVKTLGETGGLGTVATRADIIEKLFNSFLIEKK-GQDIFI-TSKGKQLLQLVPE---DLKSPALTAEWEQKLSAIAAGKLKSAVFIKDMKAYA----HQTVKEIK-N-S-S------QT--F----R-----HDNITGTACPECGKMMLKVNGKRGTMLVCQ-DR-----ECGSRKTIARK------------------TNARCPNCHKRMELR-GQGEGQTFACV----CGHREKLSVFEKRKNKDKARATKRDVSSYMKKQNKDEPINNALAEQLKKL-GLDK
25 PsiBlast_CBE 97.4633% 0 - C- -2O19 TOP3_ECOLI B:[3-636] ----------------LFIAEKPSLARAIADVLP---KPH--RKG----DG------FIEC-----G--N-GQVVTWCIGHLLEQAQ-----PDAYDSRYA------R-----WN-LADLPIVPE-KW--QLQPRPSVTKQLNVIKRFL------HEASEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQ---VQRCLINDLNPQAVERAIDRLRSNSEFV-PLCVSALARARADWLYGINMTRAYTILGRNAGYQ---------GV---------LSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADER-----------FTAIWQPS------E------------------ACEPYQDEEGRLLHRPLAEHVVNRI-SG-QPAIVTSYNDKRESESAPL-PFSLSALQIEAAKRFGLSAQNVLDICQKLYE-------T-------HKLITYPRSDCRYLPEEHFAGRHAVMNAISVHA-PD-LLPQPVVDPD-IRNR--CWDDKKVDA-HHAIIPTARS---S---A-----I-----N----LTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDI----AKGKFVAKARFL--AEAGWRTLLGSKERDEEN--D---GTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQ--DKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKK-GRYIHS-TDAGKALFHSLPE---MATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTL----YQLIDQAK-R-T--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24 PsiBlast_CBE 97.4633% 0 - C- -2O54 TOP3_ECOLI B:[3-636] ----------------LFIAEKPSLARAIADVLP---KPH--RKG----DG------FIEC-----G--N-GQVVTWCIGHLLEQAQ-----PDAYDSRYA------R-----WN-LADLPIVPE-KW--QLQPRPSVTKQLNVIKRFL------HEASEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQ---VQRCLINDLNPQAVERAIDRLRSNSEFV-PLCVSALARARADWLYGINMTRAYTILGRNAGYQ---------GV---------LSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADER-----------FTAIWQPS------E------------------ACEPYQDEEGRLLHRPLAEHVVNRI-SG-QPAIVTSYNDKRESESAPL-PFSLSALQIEAAKRFGLSAQNVLDICQKLYE-------T-------HKLITYPRSDCRYLPEEHFAGRHAVMNAISVHA-PD-LLPQPVVDPD-IRNR--CWDDKKVDA-HHAIIPTARS---S---A-----I-----N----LTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDI----AKGKFVAKARFL--AEAGWRTLLGSKERDEEN--D---GTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQ--DKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKK-GRYIHS-TDAGKALFHSLPE---MATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTL----YQLIDQAK-R-T--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23 PsiBlast_CBE 97.4633% 0 - C- -2O59 TOP3_ECOLI B:[3-639] ----------------LFIAEKPSLARAIADVLP---KPH--RKG----DG------FIEC-----G--N-GQVVTWCIGHLLEQAQ-----PDAYDSRYA------R-----WN-LADLPIVPE-KW--QLQPRPSVTKQLNVIKRFL------HEASEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQ---VQRCLINDLNPQAVERAIDRLRSNSEFV-PLCVSALARARADWLYGINMTRAYTILGRNAGYQ---------GV---------LSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADER-----------FTAIWQPS------E------------------ACEPYQDEEGRLLHRPLAEHVVNRI-SG-QPAIVTSYNDKRESESAPL-PFSLSALQIEAAKRFGLSAQNVLDICQKLYE-------T-------HKLITYPRSDCRYLPEEHFAGRHAVMNAISVHA-PD-LLPQPVVDPD-IRNR--CWDDKKVDA-HHAIIPTARS---S---A-----I-----N----LTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDI----AKGKFVAKARFL--AEAGWRTLLGSKERDEEN--D---GTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQ--DKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKK-GRYIHS-TDAGKALFHSLPE---MATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTL----YQLIDQAK-R-T--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22 PsiBlast_CBE 97.4633% 0 - C- -2O5C TOP3_ECOLI B:[3-636] ----------------LFIAEKPSLARAIADVLP---KPH--RKG----DG------FIEC-----G--N-GQVVTWCIGHLLEQAQ-----PDAYDSRYA------R-----WN-LADLPIVPE-KW--QLQPRPSVTKQLNVIKRFL------HEASEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQ---VQRCLINDLNPQAVERAIDRLRSNSEFV-PLCVSALARARADWLYGINMTRAYTILGRNAGYQ---------GV---------LSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADER-----------FTAIWQPS------E------------------ACEPYQDEEGRLLHRPLAEHVVNRI-SG-QPAIVTSYNDKRESESAPL-PFSLSALQIEAAKRFGLSAQNVLDICQKLYE-------T-------HKLITYPRSDCRYLPEEHFAGRHAVMNAISVHA-PD-LLPQPVVDPD-IRNR--CWDDKKVDA-HHAIIPTARS---S---A-----I-----N----LTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDI----AKGKFVAKARFL--AEAGWRTLLGSKERDEEN--D---GTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQ--DKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKK-GRYIHS-TDAGKALFHSLPE---MATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTL----YQLIDQAK-R-T--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21 PsiBlast_CBE 97.4633% 0 - C- -2O5E TOP3_ECOLI B:[3-636] ----------------LFIAEKPSLARAIADVLP---KPH--RKG----DG------FIEC-----G--N-GQVVTWCIGHLLEQAQ-----PDAYDSRYA------R-----WN-LADLPIVPE-KW--QLQPRPSVTKQLNVIKRFL------HEASEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQ---VQRCLINDLNPQAVERAIDRLRSNSEFV-PLCVSALARARADWLYGINMTRAYTILGRNAGYQ---------GV---------LSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADER-----------FTAIWQPS------E------------------ACEPYQDEEGRLLHRPLAEHVVNRI-SG-QPAIVTSYNDKRESESAPL-PFSLSALQIEAAKRFGLSAQNVLDICQKLYE-------T-------HKLITYPRSDCRYLPEEHFAGRHAVMNAISVHA-PD-LLPQPVVDPD-IRNR--CWDDKKVDA-HHAIIPTARS---S---A-----I-----N----LTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDI----AKGKFVAKARFL--AEAGWRTLLGSKERDEEN--D---GTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQ--DKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKK-GRYIHS-TDAGKALFHSLPE---MATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTL----YQLIDQAK-R-T--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6 PsiBlast_PDB 97.4633% 0 - C- -2O5E TOP3_ECOLI A:[3-634] ----------------LFIAEKPSLARAIADVLP---KPH--RKG----DG------FIEC-----G--N-GQVVTWCIGHLLEQAQ-----PDAYDSRYA------R-----WN-LADLPIVPE-KW--QLQPRPSVTKQLNVIKRFL------HEASEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQ---VQRCLINDLNPQAVERAIDRLRSNSEFV-PLCVSALARARADWLYGINMTRAYTILGRNAGYQ---------GV---------LSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADER-----------FTAIWQPS------E------------------ACEPYQDEEGRLLHRPLAEHVVNRI-SG-QPAIVTSYNDKRESESAPL-PFSLSALQIEAAKRFGLSAQNVLDICQKLYE-------T-------HKLITYPRSDCRYLPEEHFAGRHAVMNAISVHA-PD-LLPQPVVDPD-IRNR--CWDDKKVDA-HHAIIPTARS---S---A-----I-----N----LTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDI----AKGKFVAKARFL--AEAGWRTLLGSKERDEEN--D---GTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQ--DKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKK-GRYIHS-TDAGKALFHSLPE---MATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTL----YQLIDQAK-R-T--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5 PsiBlast_PDB 97.4633% 0 - C- -2O5C TOP3_ECOLI A:[3-634] ----------------LFIAEKPSLARAIADVLP---KPH--RKG----DG------FIEC-----G--N-GQVVTWCIGHLLEQAQ-----PDAYDSRYA------R-----WN-LADLPIVPE-KW--QLQPRPSVTKQLNVIKRFL------HEASEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQ---VQRCLINDLNPQAVERAIDRLRSNSEFV-PLCVSALARARADWLYGINMTRAYTILGRNAGYQ---------GV---------LSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADER-----------FTAIWQPS------E------------------ACEPYQDEEGRLLHRPLAEHVVNRI-SG-QPAIVTSYNDKRESESAPL-PFSLSALQIEAAKRFGLSAQNVLDICQKLYE-------T-------HKLITYPRSDCRYLPEEHFAGRHAVMNAISVHA-PD-LLPQPVVDPD-IRNR--CWDDKKVDA-HHAIIPTARS---S---A-----I-----N----LTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDI----AKGKFVAKARFL--AEAGWRTLLGSKERDEEN--D---GTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQ--DKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKK-GRYIHS-TDAGKALFHSLPE---MATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTL----YQLIDQAK-R-T--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3 PsiBlast_PDB 97.4633% 0 - C- -2O54 TOP3_ECOLI A:[3-637] ----------------LFIAEKPSLARAIADVLP---KPH--RKG----DG------FIEC-----G--N-GQVVTWCIGHLLEQAQ-----PDAYDSRYA------R-----WN-LADLPIVPE-KW--QLQPRPSVTKQLNVIKRFL------HEASEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQ---VQRCLINDLNPQAVERAIDRLRSNSEFV-PLCVSALARARADWLYGINMTRAYTILGRNAGYQ---------GV---------LSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADER-----------FTAIWQPS------E------------------ACEPYQDEEGRLLHRPLAEHVVNRI-SG-QPAIVTSYNDKRESESAPL-PFSLSALQIEAAKRFGLSAQNVLDICQKLYE-------T-------HKLITYPRSDCRYLPEEHFAGRHAVMNAISVHA-PD-LLPQPVVDPD-IRNR--CWDDKKVDA-HHAIIPTARS---S---A-----I-----N----LTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDI----AKGKFVAKARFL--AEAGWRTLLGSKERDEEN--D---GTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQ--DKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKK-GRYIHS-TDAGKALFHSLPE---MATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTL----YQLIDQAK-R-T--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2 PsiBlast_PDB 97.4633% 0 - C- -2O19 TOP3_ECOLI A:[3-637] ----------------LFIAEKPSLARAIADVLP---KPH--RKG----DG------FIEC-----G--N-GQVVTWCIGHLLEQAQ-----PDAYDSRYA------R-----WN-LADLPIVPE-KW--QLQPRPSVTKQLNVIKRFL------HEASEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQ---VQRCLINDLNPQAVERAIDRLRSNSEFV-PLCVSALARARADWLYGINMTRAYTILGRNAGYQ---------GV---------LSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADER-----------FTAIWQPS------E------------------ACEPYQDEEGRLLHRPLAEHVVNRI-SG-QPAIVTSYNDKRESESAPL-PFSLSALQIEAAKRFGLSAQNVLDICQKLYE-------T-------HKLITYPRSDCRYLPEEHFAGRHAVMNAISVHA-PD-LLPQPVVDPD-IRNR--CWDDKKVDA-HHAIIPTARS---S---A-----I-----N----LTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDI----AKGKFVAKARFL--AEAGWRTLLGSKERDEEN--D---GTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQ--DKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKK-GRYIHS-TDAGKALFHSLPE---MATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTL----YQLIDQAK-R-T--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4 PsiBlast_PDB 96.3333% 0 - C- -2O59 TOP3_ECOLI A:[3-641] ----------------LFIAEKPSLARAIADVLP---KPH--RKG----DG------FIEC-----G--N-GQVVTWCIGHLLEQAQ-----PDAYDSRYA------R-----WN-LADLPIVPE-KW--QLQPRPSVTKQLNVIKRFL------HEASEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQ---VQRCLINDLNPQAVERAIDRLRSNSEFV-PLCVSALARARADWLYGINMTRAYTILGRNAGYQ---------GV---------LSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADER-----------FTAIWQPS--------------------------CEPYQDEEGRLLHRPLAEHVVNRI-SG-QPAIVTSYNDKRESESAPL-PFSLSALQIEAAKRFGLSAQNVLDICQKLYE-------T-------HKLITYPRSDCRYLPEEHFAGRHAVMNAISVHA-PD-LLPQPVVDPD-IRNR--CWDDKKVDA-HHAIIPTARS---S---A-----I-----N----LTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDI----AKGKFVAKARFL--AEAGWRTLLGSK-----N--D---GTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQ--DKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKK-GRYIHS-TDAGKALFHSLPE---MATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTL----YQLIDQAK-R-T--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26 HHSearch 76.3934% -89 - C1 -1I7D TOP3_ECOLI A:[1-620] --------------MRLFIAEKPSLARAIADVL----PKPH-RKG----DG------FIE------C--GNGQVVTWCIGHLLEQAQ-----PDAYDSRYA------R-----WN-LADLPIVPE-KW--QLQPRPSVTKQLNVIKRFL----HEA--SEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQ---VQRCLINDLNPQAVERAIDRLRSNSEFV-PLCVSALARARADWLYGINMTRAYT-----ILGRNAGYQ----GV---------LSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHI-----VTPADER------FTAIWQPSEACEPYQ------------------D------EEGRLLHRPLAEHVVNRI-SG-QPAIVTSYNDKRESESAPL-PFSLSALQIEAAKRFGLSAQNVLDICQKLYE-------T-------HKLITFPRSDCRYLPEEHFAGRHAVMNAISVH--AP-DLLPQ-PVVD-PDIRNRCWDDKKVDA-HHAIIPTARS---S---A----------IN----LTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDI----AKGKFVAKARFL--AEAGWRTLLGSKERDE-----ENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKD--LKKILRATDGLGTEATRAGIIELLFKRGFLTKK-GRYIHS-TDAGKALFHSLPE---MATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTL----YQLIDQAK-R-T-----------------P-----VRQFRGIVAP-----------------------------------------------------------------------------------------------------------------------------------------------
1 PsiBlast_PDB 75.2133% -93 - C1 -1D6M - TOP3_ECOLI A:[3-609] ----------------LFIAEKPSLARAIADVLP---KPH--RKG----DG------FIEC-----G--N-GQVVTWCIGHLLEQAQ-----PDAYDSRYA------R-----WN-LADLPIVPE-KW--QLQPRPSVTKQLNVIKRFL------HEASEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQ---VQRCLINDLNPQAVERAIDRLRSNSEFV-PLCVSALARARADWLYGINMTRAYTILG---------------GV---------LSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADER-----------FTAIWQPS------E------------------ACEPYQDEEGRLLHRPLAEHVVNRI-SG-QPAIVTSYNDKRESESAPL-PFSLSALQIEAAKRFGLSAQNVLDICQKLYE-------T-------HKLITYPRSDCRYLPEEHFAGRHAVMNAISVHA-PD-LLPQPVVDPD-IRNR--CWDDKKVDA-HHAIIPTARS---S---A-----I-----N----LTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDI----AKGKFVAKARFL--AEAGWRTLLGSKERDEEN--D---GTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQ--DKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKK-GRYIHS-TDAGKALFHSLPE---MATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTL----YQLIDQAK-R-T--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7 PsiBlast_PDB 75.1233% -93 - C1 -1I7D TOP3_ECOLI A:[3-609] ----------------LFIAEKPSLARAIADVLP---KPH--RKG----DG------FIEC-----G--N-GQVVTWCIGHLLEQAQ-----PDAYDSRYA------R-----WN-LADLPIVPE-KW--QLQPRPSVTKQLNVIKRFL------HEASEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQ---VQRCLINDLNPQAVERAIDRLRSNSEFV-PLCVSALARARADWLYGINMTRAYTILGRNAGYQ---------GV---------LSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADER-----------FTAIWQPS------E------------------ACEPYQDEEGRLLHRPLAEHVVNRI-SG-QPAIVTSYNDKRESESAPL-PFSLSALQIEAAKRFGLSAQNVLDICQKLYE-------T-------HKLITFPRSDCRYLPEEHFAGRHAVMNAISVHA-PD-LLPQPVVDPD-IRNR--CWDDKKVDA-HHAIIPTARS---S---A-----I-----N----LTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDI----AKGKFVAKARFL--AEAGWRTLLGSKERDEEN--D---GTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQ--DKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKK-GRYIHS-TDAGKALFHSLPE---MATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTL----YQLIDQAK-R-T--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28 HHSearch 63.0026% -75 - C1 -4CGY TOP3A_HUMAN A:[34-640] ------------VRKVLCVAEKNDAAKGIADLL----SNGRMRRR----EGLSKFNKIYEFDYHLYGQNV-TMVMTSVSGHLLAHDF-----QMQF----R------K-----WQ--SCNPLVLF-EA--EIEK--YCPENFVDIKKTLERETRQC--QALVIWTDCDREGENIGFEIIHVCKAVKP-NLQ---VLRARFSEITPHAVRTACENLTEPDQ---RVSDAVDVRQELDLRIGAAFTRFQT-----LRLQRIFPEVLAEQL---------ISYGSCQFPTLGFVVERFKAIQAFVPEIFHRIKVTH-----DHKDGI-------VEFNWK-----------------------------------RHRLFNHTACLVLYQLC-VEDPMATVVEVRSKPKSKWRPQ-ALDTVELEKLASRKLRINAKETMRIAEKLYT-------Q--------GYISYPRTETNIFPRDLN--LTVLVEQQTPDPRWG-AFAQS--ILE-RGGPTPRNGNKSDQA-HPPIHPTKYT---N---------------N----LQGDEQRLYEFIVRHFLACCSQDAQGQETTVEIDI----AQERFVAHGLMI--LARNYLDVYPYDHW---------SDKILPVYEQGSHFQPSTVEMVDGETSPPKLLTEADLIALME-------------------KHGIGTDATHAEHIETIKARMYVGLTPDKRFLP-GHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICDGKKDKFVVLRQQVQKYKQVFIEAVAKAK-KLDEA------LAQYFGNGT---------------------------------------------------------------------------------------------------------------------------------------------------------------
27 HHSearch 62.2425% -71 - C1 -4RUL TOP1_ECOLI A:[4-709] -------------GKALVIVESPAKAKTINKYL----GS--------------------------------DYVVKSSVGHIRDLPT--------------KDERGAL-----VNRMGVDPWHNW-EA--HYEVLPGKEKVVSELKQLA----EKA--DHIYLATDLDREGEAIAWHLREVIGGD---DAR---YSRVVFNEITKNAIRQAFNKPGELNI---DRVNAQQARRFMDRVVGYMVSPLLW-----KKIA---------RG---------LSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDAST-----TTPSGEA------LALQVTHQ------N------------------D------KPFRPVNKEQTQAAVSLL-EK-ARYSVLEREDKPTTSKPGA-PFITSTLQQAASTRLGFGVKKTMMMAQRLYE-------A--------GYITYMRTDSTNLSQDAVNMVRGYISDNFGK-----KY------LP-ESPNQYASK---QEA-HEAIRPSDVN---VMAES-----L----KD----MEADAQKLYQLIWRQFVACQMTPAKYDSTTLTVGA----GDFRLKARGRIL--RFDGWTKVMPALRKG-------DEDRILPAVNKGDALTLVELTPAQHFTKPPARFSEASLVKELE-------------------KRGIGRPSTYASIISTIQDRGYVRVE-NRRFYA-EKMGEIVTDRLEENFRELMNYDFTAQMENSLDQVANHEAEWKAVLDHFFSDF----TQQLDKAE-KDPEE------GG--MRP--N-----QMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHVCGNNPTCDGYE--------------------------------------------------
50 Fugue 60.4526% -64 * C1 *4CGY TOP3A_HUMAN A:[22-640] FSRAAMEMALRGVRKVLCVAEKNDAAKGIADLLSNGRMRR--REGLSKFNK------IYE------F--D-YHLYGQNVTMVMTSVSGHLL-AHDFQMQFR------K-----WQ-SCNPLVLFE-AE--IEKYCPENFVDIKKTLERE----TRQ-CQALVIWTDCDREGENIGFEIIHVCKA----VKPNLQVLRARFSEITPHAVRTACENLTEPD--Q-RVSDAVDVRQELDLRIGAAFTRFQT-----LRLQ---------RIFPEVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPEIFHRIKVTH-----DHKDGI-------VEFNWKRH-----------------------------------RLFNHTACLVLYQLCVED-PMATVVEVRSKPKSKWRPQ-ALDTVELEKLASRKLRINAKETMRIAEKLYT-------Q-------GY-ISYPRTETNIFPRDL--NLTVLVEQQTPDPRWG-AFAQSILERGGPTPRNGNKSDQA----HPPIHPTKYT------------------NN----LQGDEQRLYEFIVRHFLACCSQDAQGQETTVEIDI----AQERFVAHGLMI--LARNYLDVYPY---------DHWSDKILPVYEQGSHFQPSTVEMVDGETSPPKLLTEADLIALMEKH-------------------GIGTDATHAEHIETIKARMYVGLT-PDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICDGK----------------------------------------------------------------------------------------------------------------------------------------------------------------------KDKFVVLRQQVQKYKQVFIEAVAKAKKLDEALAQYFGNGT
31 HHSearch 60.2826% -77 - C1 -1MW9 TOP1_ECOLI X:[2-580] -------------GKALVIVESPAKAKTINKYL----GS--------------------------------DYVVKSSVGHIRDLPT---------------------ERGALVNRMGVDPWHNW-EA--HYEVLPGKEKVVSELKQLA----EKA--DHIYLATDLDREGEAIAWHLREVIGGD---DAR---YSRVVFNEITKNAIRQAFNKPG--ELNI-DRVNAQQARRFMDRVVGYMVSPLLW-----KKIA---------RG---------LSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDAST-----TTPSGEA------LALQVTHQ------N------------------D------KPFRPVNKEQTQAAVSLL-EK-ARYSVLEREDKPTTSKPGA-PFITSTLQQAASTRLGFGVKKTMMMAQRLYE-------A--------GYITYMRTDSTNLSQDAVNMVRGYISDNFGK-----KY------LP-ESPNQYA---------REAIRPSDVN---VMAES-----L----KD----MEADAQKLYQLIWRQFVACQMTPAKYDSTTLTVGA----GDFRLKARGRIL--RFDGWTKVMPAL-----------EDRILPAVNKGDALTLVELTPAQHFTKPPARFSEASLVKELE-------------------KRGIGRPSTYASIISTIQDRGYVRVE-NRRFYA-EKMGEIVTDRLEENFRELMNYDFTAQMENNLDQVANHEA