@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu04490: (2016-06-07 )
MAEPILHIEGLDKKIGSKQILKQISMDVMEGEIIGLLGPNGSGKTTLIRIIVGLLKQNSGSVTISGFQHDTEFEKAMEAVGAIVENPEFYPYLTGWENLKHFANMHKKIADERLDEVVERVGLTSAIHDKVKTYSLGMRQRLGIAQAILHRPKLLILDEPTNGLDPAGMKDFRDHIKELAEMEGTAVLFATHLLREVEDLCDRVIIIQKGEIKAEVSLQGTDQTTEKAIIEVQPQEKALNWLTGNQYQAESQDGTIVVEVAKENIPELNRSLVGQDLNVFSITPYTQSLEDEFIKATTAHQEEGEELV
Atome Classification :
(25 SA)
.........10.....----...20........30........40........50........60.....---------------.----.---.--70--...-......80........90........100--......-----...110-.........120--....-...------..130...----.....140.......150.......160.......170.......180.......190.......200.......210.-----......220.....--..230.......240...-.----...250--..-.--...--.260...--....270.......280.......290.......300.......----------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MAE
P
I
L
H
I
EGL
D
K
KI
G
----
S
K
Q
I
L
K
Q
I
S
M
D
VME
G
E
I
I
G
L
LGPNGSG
K
T
T
L
I
R
I
I
V
G
L
L
KQNSG
S
V
T
I
SG---------------F----Q---H--
D
---
T
E
F
-
E
K
A
M
E
A
V
G
A
I
VENPEFYPYLT
G
W
E
N
L
K
----
H
F
A
N
M
H
-----
K
K
I
A
---
D
E
R
L
D
E
V
V
E
R----VG
L
T
-
S
A
I
------
H
D
K
-
V
K
T
Y
----
S
L
G
M
R
Q
RL
G
I
A
Q
A
I
LHRP
K
L
L
I
L
DEPTNGLD
P
A
G
M
K
D
F
R
D
H
I
K
E
L
A
E
MEG
T
A
V
L
F
A
T
H
L
L
R
E
V
E
D
LCD
R
V
I
I
I
QKG
E
I
K
-----
A
E
V
S
L
QGTDQTT
E
K
--
A
I
I
E
VQ
P
Q
E
K
ALNWLTGN-Q----YQAESQ--D
G
-
T
--
I
V
V
--
E
V
A
K
E
N
I
--
P
E
L
N
R
S
L
VGQDL
N
V
F
S
ITP
Y
T
Q
S
L
E
D
E
F
I
K
A
TTAH-QEEGEELV----------------
10
PsiBlast_PDB
83.69
31%
-95
- C1 -
4YER
4
?
A:
[3-313]
--
E
D
I
I
V
V
E
N
L
V
K
K
F
G
----
D
F
E
A
V
K
G
V
S
F
S
V
K
K
G
E
I
F
A
F
L
G
P
N
G
A
G
K
T
T
T
I
H
M
L
T
T
L
L
K
P
T
S
G
K
A
W
V
A
G
---------------
H
----
D
---
V
--
L
---
K
E
P
-
R
E
V
R
R
K
I
G
I
V
F
Q
D
Q
S
L
D
R
E
L
T
A
Y
E
N
--------
M
Y
I
H
-----
G
K
I
Y
---
G
Y
G
G
E
K
L
K
K
R
----
I
L
E
L
-
L
E
F
V
ELLEF
K
D
K
P
V
K
T
F
----
S
G
G
M
A
R
R
L
E
I
A
R
S
L
I
H
E
P
E
V
L
F
L
D
E
P
T
I
G
L
D
P
H
T
R
A
H
M
W
E
Y
I
S
K
M
K
K
E
H
N
M
T
I
F
L
T
T
H
Y
M
D
E
A
E
Q
L
A
D
R
V
A
I
I
D
H
G
K
I
I
-----
A
L
G
T
P
T
E
L
K
R
M
V
G
K
--
E
I
I
Y
V
R
-----------
D
-
F
----
I
E
S
C
R
K
L
P
D
G
-
R
L
E
L
N
V
--
E
D
--------------------
I
E
E
I
T
Y
H
K
P
T
L
N
D
V
F
L
H
L
T
G
R
E
L
R
E
E
G
P
E
------------------
1
PsiBlast_PDB
79.93
42%
-128
- C1 -
1VPL
2
?
A:
[18-224]
-------
V
K
D
L
R
K
R
I
G
----
K
K
E
I
L
K
G
I
S
F
E
I
E
E
G
E
I
F
G
L
I
G
P
N
G
A
G
K
T
T
T
L
R
I
I
S
T
L
I
K
P
S
S
G
I
V
T
V
F
G
---------------
K
----
N
---
V
--
V
---
E
E
P
-
H
E
V
R
K
L
I
S
Y
L
P
E
E
A
G
A
Y
R
N
M
Q
G
I
E
Y
L
R
----
F
V
A
G
F
Y
-----
A
S
S
S
---
S
E
-
I
E
E
M
V
E
R
A
T
E
I
A
G
L
G
-
E
K
I
------
K
D
R
-
V
S
T
Y
----
S
K
G
M
V
R
K
L
L
I
A
R
A
L
M
V
N
P
R
L
A
I
L
D
E
P
T
S
G
L
D
V
L
N
A
R
E
V
R
K
I
L
K
Q
-
A
S
Q
E
G
L
T
I
L
V
S
S
H
N
M
L
E
V
E
F
L
C
D
R
I
A
L
I
H
N
G
T
I
--------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
74.92
32%
-135
- C1 -
4YMU
2
?
A:
[1-217]
----
M
I
F
V
N
D
V
Y
K
N
F
G
----
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
---------------
V
----
K
---
I
--
N
NGK
V
N
I
-
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
LAPV
K
V
K
K
M
N
-----
K
K
E
A
---
E
E
L
A
V
D
L
L
A
K
----
V
G
L
L
-
D
K
K
------
D
Q
Y
-
P
I
K
L
----
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
-----
E
E
------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
74.40
32%
-133
- C1 -
4YMT
-
?
J:
[1-217]
----
M
I
F
V
N
D
V
Y
K
N
F
G
----
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
---------------
V
----
K
---
I
--
N
NGK
V
N
I
-
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
LAPV
K
V
K
K
M
N
-----
K
K
E
A
---
E
E
L
A
V
D
L
L
A
K
----
V
G
L
L
-
D
K
K
------
D
Q
Y
-
P
I
K
L
----
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
-----
E
E
------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
74.40
32%
-133
- C1 -
4YMS
-
?
J:
[1-217]
----
M
I
F
V
N
D
V
Y
K
N
F
G
----
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
---------------
V
----
K
---
I
--
N
NGK
V
N
I
-
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
LAPV
K
V
K
K
M
N
-----
K
K
E
A
---
E
E
L
A
V
D
L
L
A
K
----
V
G
L
L
-
D
K
K
------
D
Q
Y
-
P
I
K
L
----
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
-----
E
E
------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
73.78
30%
-111
- C1 -
2IT1
-
?
A:
[4-263]
-----
I
K
L
E
N
I
V
K
K
F
G
----
N
F
T
A
L
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
T
S
G
K
I
Y
F
D
E
--------------------
K
---
D
--
V
---
T
E
L
-
P
P
K
D
R
N
V
G
L
V
F
Q
N
W
A
L
Y
P
H
M
T
V
Y
K
N
I
A
-----
F
P
L
E
L
-----
R
K
A
P
---
R
E
E
I
D
K
K
V
R
E
----
V
A
K
M
-
L
H
I
------
D
K
L
-
L
N
R
Y
PWQL
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
E
L
K
R
L
Q
K
E
L
G
I
T
T
V
Y
V
T
H
D
Q
A
E
A
L
A
M
A
D
R
I
A
V
I
R
E
G
E
I
--------
L
Q
V
G
T
P
D
E
V
Y
Y
K
--------
P
K
Y
K
F
V
G
G
F
L
G
N
-
P
P
M
N
F
V
E
A
K
V
E
--
D
G
-
K
--
L
V
I
T-
E
K
S
K
L
P
I
--
P
K
----------------------------------------------------------
21
PsiBlast_CBE
73.52
32%
-132
- C1 -
4YMV
1
?
A:
[1-217]
----
M
I
F
V
N
D
V
Y
K
N
F
G
----
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
---------------
V
----
K
---
I
--
N
NGK
V
N
I
-
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
LAPV
K
V
K
K
M
N
-----
K
K
E
A
---
E
E
L
A
V
D
L
L
A
K
----
V
G
L
L
-
D
K
K
------
D
Q
Y
-
P
I
K
L
----
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
-----
E
E
------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
73.40
32%
-131
- C1 -
4YMW
-
?
J:
[1-217]
----
M
I
F
V
N
D
V
Y
K
N
F
G
----
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
---------------
V
----
K
---
I
--
N
NGK
V
N
I
-
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
LAPV
K
V
K
K
M
N
-----
K
K
E
A
---
E
E
L
A
V
D
L
L
A
K
----
V
G
L
L
-
D
K
K
------
D
Q
Y
-
P
I
K
L
----
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
-----
E
E
------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
73.30
32%
-119
- C1 -
4U02
1
?
A:
[2-219]
--
E
P
I
I
R
I
R
N
L
H
K
W
F
G
----
P
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
---------------
L
SV--
K
---
D
--
D
---
R
A
L
-
R
E
I
R
R
E
V
G
M
V
F
Q
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
T
-----
L
A
P
M
R
VRRWP
R
E
K
A
---
E
K
K
A
L
E
L
L
E
R
----
V
G
I
L
-
D
Q
A
------
R
K
Y
-
P
A
Q
L
----
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
Q
-
G
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
-----
E
E
------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
73.28
32%
-119
- C1 -
4U02
1
?
D:
[2-219]
--
E
P
I
I
R
I
R
N
L
H
K
W
F
G
----
P
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
---------------
L
SV--
K
---
D
--
D
---
R
A
L
-
R
E
I
R
R
E
V
G
M
V
F
Q
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
T
-----
L
A
P
M
R
VRRWP
R
E
K
A
---
E
K
K
A
L
E
L
L
E
R
----
V
G
I
L
-
D
Q
A
------
R
K
Y
-
P
A
Q
L
----
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
Q
-
G
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
-----
E
E
------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
72.95
32%
-133
- C1 -
4YMV
1
?
J:
[1-217]
----
M
I
F
V
N
D
V
Y
K
N
F
G
----
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
---------------
V
----
K
---
I
--
N
NGK
V
N
I
-
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
LAPV
K
V
K
K
M
N
-----
K
K
E
A
---
E
E
L
A
V
D
L
L
A
K
----
V
G
L
L
-
D
K
K
------
D
Q
Y
-
P
I
K
L
----
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
-----
E
E
------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
72.86
32%
-130
- C1 -
4YMU
2
?
J:
[1-217]
----
M
I
F
V
N
D
V
Y
K
N
F
G
----
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
---------------
V
----
K
---
I
--
N
NGK
V
N
I
-
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
LAPV
K
V
K
K
M
N
-----
K
K
E
A
---
E
E
L
A
V
D
L
L
A
K
----
V
G
L
L
-
D
K
K
------
D
Q
Y
-
P
I
K
L
----
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
-----
E
E
------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
72.77
32%
-128
- C1 -
4U02
1
?
C:
[2-219]
--
E
P
I
I
R
I
R
N
L
H
K
W
F
G
----
P
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
---------------
L
SV--
K
---
D
--
D
---
R
A
L
-
R
E
I
R
R
E
V
G
M
V
F
Q
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
T
-----
L
A
P
M
R
VRRWP
R
E
K
A
---
E
K
K
A
L
E
L
L
E
R
----
V
G
I
L
-
D
Q
A
------
R
K
Y
-
P
A
Q
L
----
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
Q
-
G
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
-----
E
E
------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
72.66
32%
-120
- C1 -
4U02
1
?
B:
[2-219]
--
E
P
I
I
R
I
R
N
L
H
K
W
F
G
----
P
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
---------------
L
SV--
K
---
D
--
D
---
R
A
L
-
R
E
I
R
R
E
V
G
M
V
F
Q
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
T
-----
L
A
P
M
R
VRRWP
R
E
K
A
---
E
K
K
A
L
E
L
L
E
R
----
V
G
I
L
-
D
Q
A
------
R
K
Y
-
P
A
Q
L
----
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
Q
-
G
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
-----
E
E
------------------------------------------------------------------------------------------------------------------------------
51
Fugue
72.50
23%
-129
- C1 -
3TUZ
3
METN_ECOLI
H:
[23-362]
---
H
M
I
K
L
S
N
I
T
K
V
F
H
QGTR
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
---------------
Q
ELTT
L
---
S
--
E
---
S
E
L
-
T
K
A
R
R
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
A
----
L
P
L
E
L
D
NTP--
K
D
E
V
---
K
R
R
V
T
E
L
L
S
L
----
V
G
L
G
-
D
K
H
------
D
S
Y
-
P
S
N
L
----
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
EQDTV
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
--
F
I
Q
S
T
L
H
L
D
I
P
E
D
Y
Q
E
R
L
-
Q
----
A
E
P
F
T
D
--
C
V
P
M
--
L
R
L
--
E
F
T
G
Q
S
V
DA
P
L
L
S
E
T
A
R
R
F
N
V
N
N
N
I
I
S
A
Q
M
D
Y
A
G
G
V
K
F
G
I
M
L
T
E
-
M
H
G
T
Q
Q
D
T
QAAIAWLQEHHVKVEV
8
PsiBlast_PDB
72.22
32%
-128
- C1 -
4U00
3
?
A:
[3-219]
---
P
I
I
R
I
R
N
L
H
K
W
F
G
----
P
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
---------------
L
SV--
K
---
D
--
D
---
R
A
L
-
R
E
I
R
R
E
V
G
M
V
F
Q
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
T
-----
L
A
P
M
R
V
RRWP
R
E
K
A
---
E
K
K
A
L
E
L
L
E
R
----
V
G
I
L
-
D
Q
A
------
R
K
Y
-
P
A
Q
L
----
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
Q
-
G
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
-----
E
E
------------------------------------------------------------------------------------------------------------------------------
35
PsiBlast_CBE
71.64
31%
-145
- C1 -
2OUK
1
?
A:
[24-237]
----
M
I
D
V
H
Q
L
K
K
S
F
G
----
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
---------------
I
----
N
LKA
K
--
D
---
T
N
L
-
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
-----
L
A
P
M
K
V
RKWP
R
E
K
A
---
E
A
K
A
M
E
L
L
D
K
----
V
G
L
K
-
D
K
A
------
H
A
Y
-
P
D
S
L
----
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
--------------------------------------------------------------------------------------------------------------------------------------
32
PsiBlast_CBE
71.36
31%
-138
- C1 -
2OUK
1
?
D:
[24-237]
----
M
I
D
V
H
Q
L
K
K
S
F
G
----
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
---------------
I
----
N
LKA
K
--
D
---
T
N
L
-
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
-----
L
A
P
M
K
VRKWP
R
E
K
A
---
E
A
K
A
M
E
L
L
D
K
----
V
G
L
K
-
D
K
A
------
H
A
Y
-
P
D
S
L
----
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
--------------------------------------------------------------------------------------------------------------------------------------
39
PsiBlast_CBE
70.70
31%
-139
- C1 -
2OLK
1
?
A:
[24-237]
----
M
I
D
V
H
Q
L
K
K
S
F
G
----
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
---------------
I
----
N
LKA
K
--
D
---
T
N
L
-
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
-----
L
A
P
M
K
VRKWP
R
E
K
A
---
E
A
K
A
M
E
L
L
D
K
----
V
G
L
K
-
D
K
A
------
H
A
Y
-
P
D
S
L
----
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
--------------------------------------------------------------------------------------------------------------------------------------
75
HHSearch
70.32
29%
-141
- C1 -
4RVC
-
?
A:
[2-225]
---
T
L
L
E
V
K
D
L
S
G
G
Y
T
----
A
Q
N
V
L
E
D
V
T
F
V
V
D
R
G
E
M
V
A
L
I
G
L
N
G
A
G
K
S
T
T
I
K
H
I
I
G
L
M
E
P
R
R
G
A
I
S
I
N
G
---------------
Y
----
R
---
L
--
A
---
D
G
P
-
E
T
Y
R
R
Q
F
A
Y
I
P
E
T
P
V
L
Y
E
E
L
T
L
E
E
H
L
R
----
L
A
A
M
A
Y
-----
G
L
S
E
A
E
Y
E
R
R
L
P
P
L
L
R
E
----
F
R
L
E
-
R
R
L
------
S
S
F
-
P
A
H
F
----
S
K
G
M
K
Q
K
V
M
I
V
C
A
F
L
L
E
P
P
L
Y
I
I
D
E
P
F
L
G
L
D
P
L
A
I
H
A
L
L
E
R
M
N
E
Q
K
A
-
K
G
A
G
I
L
L
S
T
H
I
L
A
T
A
E
R
Y
C
D
S
F
V
I
L
H
N
G
R
V
K
-----
A
K
G
T
L
D
D
I
R
R
Q
F
--------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
67.17
31%
-132
- C1 -
3C41
3
?
J:
[3-216]
----
M
I
D
V
H
Q
L
K
K
S
F
G
----
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
---------------
I
----
N
LKA
K
--
D
---
T
N
L
-
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
-----
L
A
P
M
K
VRKWP
R
E
K
A
---
E
A
K
A
M
E
L
L
D
K
----
V
G
L
K
-
D
K
A
------
H
A
Y
-
P
D
S
L
----
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
--------------------------------------------------------------------------------------------------------------------------------------
46
PsiBlast_CBE
49.17
31%
-130
- C1 -
4HLU
2
ECFA2_THEMA
A:
[22-217]
---------------------
K
K
A
L
E
N
V
S
L
V
I
N
E
G
E
C
L
L
V
A
G
N
T
G
S
G
K
S
T
L
L
Q
I
V
A
G
L
I
E
P
T
S
G
D
V
L
Y
D
G
E
R
K
K
G
Y
E
I
R
R
N
I
G
I
A
F
----
Q
---
Y
PE
D
---
Q
F
F
A
E
R
V
F
D
E
V
A
F
A
V
K
N
--
F
Y
P
D
R
D
P
V
P
L
V
K
---------------------------
K
A
M
E
F
----
V
G
L
D
F
D
S
F
------
K
D
R
-
V
P
F
F
L---
S
G
G
E
K
R
R
V
A
I
A
S
V
I
V
H
E
P
D
I
L
I
L
D
E
P
L
V
G
L
D
R
E
G
K
T
D
L
L
-
R
I
V
E
K
W
K
T
L
G
K
T
V
I
L
I
S
H
D
I
E
T
V
I
N
H
V
D
R
V
V
V
L
E
K
G
K
---------------------------------------------------------------------------------------------------------------------------------------
45
PsiBlast_CBE
48.92
31%
-131
- C1 -
4HLU
3
ECFA2_THEMA
B:
[22-217]
---------------------
K
K
A
L
E
N
V
S
L
V
I
N
E
G
E
C
L
L
V
A
G
N
T
G
S
G
K
S
T
L
L
Q
I
V
A
G
L
I
E
P
T
S
G
D
V
L
Y
D
G
ERKKGYEIRRNIGIA
F
----
Q
---
Y
PE
D
---
Q
F
F
A
E
R
V
F
D
E
V
A
F
A
V
K
N
--
F
Y
P
D
R
D
P
V
P
L
V
K
---------------------------
K
A
M
E
F
----
V
G
L
D
F
D
S
F
------
K
D
R
-
V
P
F
F
L---
S
G
G
E
K
R
R
V
A
I
A
S
V
I
V
H
E
P
D
I
L
I
L
D
E
P
L
V
G
L
D
R
E
G
K
T
D
L
L
-
R
I
V
E
K
W
K
T
L
G
K
T
V
I
L
I
S
H
D
I
E
T
V
I
N
H
V
D
R
V
V
V
L
E
K
G
K
---------------------------------------------------------------------------------------------------------------------------------------
57
HHSearch
48.02
30%
16
- C1 -
4YER
4
?
A:
[2-309]
-
M
E
D
I
I
V
V
E
N
L
V
K
K
F
G
----
D
F
E
A
V
K
G
V
S
F
S
V
K
K
G
E
I
F
A
F
L
G
P
N
G
A
G
K
T
T
T
I
H
M
L
T
T
L
L
K
P
T
S
G
K
A
W
V
A
G
---------------
H
----
D
---
V
--
L
---
K
E
P
-
R
E
V
R
R
K
I
G
I
V
F
Q
D
Q
S
L
D
R
E
L
T
A
Y
E
N
M
Y
----
I
H
G
K
I
Y
-----
G
Y
G
G
E
K
L
K
K
R
I
L
E
L
L
E
F
----
V
E
L
L
-
E
F
K
------
D
K
P
-
V
K
T
F
----
S
G
G
M
A
R
R
L
E
I
A
R
S
L
I
H
E
P
E
V
L
F
L
D
E
P
T
I
G
L
D
P
H
T
R
A
H
M
W
E
Y
I
S
K
M
K
K
E
H
N
M
T
I
F
L
T
T
H
Y
M
D
E
A
E
Q
L
A
D
R
V
A
I
I
D
H
G
K
I
I
-----
A
L
G
T
P
T
E
L
K
R
M
V
G
K
E
I
I
Y
V
R
------------
D
F
I
E
----
S
C
R
K
L
P
--
D
G
-
R
--
L
E
L
N
V
E
D
--------------------
I
E
E
I
T
Y
H
K
P
T
L
N
D
V
F
L
H
L
T
G
R
E
-
L
R
E
---------------------
44
PsiBlast_CBE
45.74
31%
-126
- C1 -
4ZIR
5
ECFA2_THEMA
A:
[21-216]
---------------------
K
K
A
L
E
N
V
S
L
V
I
N
E
G
E
C
L
L
V
A
G
N
T
G
S
G
K
S
T
L
L
Q
I
V
A
G
L
I
E
P
T
S
G
D
V
L
Y
D
G
EKGYEIRRN
I
G
I
A
--
F
----
Q
---
Y
PE
D
---
Q
F
F
A
E
R
V
F
D
E
V
A
F
A
V
K
N
--
F
Y
P
D
R
D
P
V
P
L
V
K
---------------------------
K
A
M
E
F
----
V
G
L
D
F
D
S
F
------
K
D
R
-
V
P
F
F
L---
S
G
G
E
K
R
R
V
A
I
A
S
V
I
V
H
E
P
D
I
L
I
L
D
E
P
L
V
G
L
D
R
E
G
K
T
D
L
L
-
R
I
V
E
K
W
K
T
L
G
K
T
V
I
L
I
S
H
D
I
E
T
V
I
N
H
V
D
R
V
V
V
L
E
K
G
K
---------------------------------------------------------------------------------------------------------------------------------------