@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu06100: (2016-06-09 )
MEISKQTSDLLLSLEKKKGTLPKFSVLRSIPRNRIIYGAPGTGKSNYLEREVGKIFGDNPYVFTRVTFFPGYTYGQFIGAYKPVPIYKKLSGEEEIFSSNFRDKMENFEPMIDYQFVPGPFIDVLIKALKNRYTNFILIIEEINRANAASVFGDIFQLLDRNKNGESDYPVTFGPDIMNYLARNGIKDEMIKLPSNFFIWATMNNADQGVLPLDTAFKRRWSFEYLELEKYRKAVDSWKLSLRYKGHNKVIMWNDFRDIINKRLKGKVPEDKLLGPFFLKESELWNQNVFKNKLLYYLKEDVFKHNPTIDFLNASTFSELIEKYDGSDNIFTFDIDDSSFVSD
Atome Classification :
(20 SA)
--------.........10........20.......----.30......-.--.40........-50........---60........70........80..------..-....90.-.......100.......-----.110.-.---..-...120.....------...130..----....-.-140.......---150.......160.......170.--......180.....-----..190.......200.....-..210.......--220.-.-.....230.......240.......250.......260.......270.......280..---......290.......300.......310.......320.......330.......340.-------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------MEIS
K
Q
T
S
D
L
L
L
S
L
E
K
KKGTL
P
K
F
S
V
L
R
----SIPRN
R
I
I
Y-G--APGTGK
S
N
Y
L
E
-
R
E
V
G
K
IFGDN---
P
Y
V
F
T
R
V
T
FFPGY
T
Y
G
Q
F
IGAYKP------V
P
-
I
Y
KKLSG-
E
E
E
I
F
S
S
N
F
-
R
D
K
M
ENF-----EP
M
I
D
-
Y
---QF-VPG
P
-
F
I
D
V
L
I
------
K
A
L
K
NRYT----
N
F
I
L
-
I
-
I
EEINRA
N
A
A
---
S
V
F
G
D
I
F
Q
L
L
DRNKNGESDY
P
V
TF--
G
P
D
I
M
N
Y
L
A
RNGI
K
-----
D
E
M
I
KLPS
N
F
F
I
W
A
TMNNAD-QGVLP
L
D
T
A
F
K
R
--RWS
F
-
E
-
Y
L
E
L
E
K
Y
R
K
A
V
DS
W
K
L
S
L
R
YKGH
N
K
V
I
M
W
N
D
F
R
D
I
I
N
K
R
LKGKVPEDKLL
G
P
F
FL
K
E
-
S
E
---LWN
Q
N
V
F
K
N
K
L
L
Y
Y
L
K
E
D
V
FKHNPT
I
D
FL
N
A
S
T
F
S
E
L
I
E
KYDGSD
N
I
F
T
F
DIDDSSFVSD-------------------
21
HHSearch
84.80
21%
-142
- C2 -
2R44
5
?
A:
[37-193]
-----------------------------
N
R
L
L
I
G
I
----
C
T
G
G
H
I
L
L
E
-
G
--
V
P
G
L
A
K
T
L
S
V
N
-
T
L
A
K
T
M
-------
D
L
D
F
H
R
I
Q
F
T
P
D
L
L
P
S
D
L
I
G
T
M
I
Y
------
N
Q
-
H
-----------------------------
K
G
--
N
-
F
---
E
V
-
K
K
G
P
-------------------
V
F
----
S
N
F
I
-
L
-
A
D
E
V
N
R
S
P
A
K
----
V
Q
S
A
L
L
E
C
M
Q
E
K
Q
-------
V
T
---------------
I
G
-----
D
T
T
Y
P
L
D
N
P
F
L
V
L
A
T
Q
N
P
V
E
Q
E
G
T
Y
P
L
P
E
A
Q
V
D
--
R
F
M
M
K
I
-
H
L
T
Y
L
D
K
E
S
E
L
E
V
---------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
81.66
18%
-153
- C2 -
5C3C
1
?
A:
[39-207]
------------------------------
L
Y
R
A
G
Y
----
E
A
R
I
P
M
M
L
K
-
G
--
P
T
G
C
G
K
S
R
F
V
E
-
H
M
A
W
K
L
-------
N
R
P
L
I
T
I
A
C
N
E
D
M
T
A
S
D
L
V
G
R
--------------------------------------------------------
D
G
P
-
L
T
V
A
A
-------------
R
I
----
G
A
I
C
-
Y
-
L
D
E
I
V
E
A
R
Q
D
----
T
I
V
V
I
H
P
L
T
D
H
R
R
------
V
L
P
-------------
L
E
K
K
-----
G
E
L
V
E
A
H
P
D
F
Q
I
V
I
S
Y
N
P
-------
D
L
K
Q
S
T
K
Q
--
R
F
G
A
-
L
-
D
F
D
Y
P
K
P
D
I
E
A
E
I
---------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
74.83
14%
-139
- C2 -
3NBX
1
RAVA_ECOLI
X:
[24-190]
---------------------
L
Y
E
R
S
H
A
I
R
L
C
L
L
A
A
----
L
S
G
E
S
V
F
L
L
-
G
--
P
P
G
I
A
K
S
L
I
A
R
-
R
L
K
F
A
F
Q
N
-----
A
R
A
F
E
Y
L
-
M
T
R
F
S
T
P
E
E
V
F
G
P
L
S
----------------------------------------------
E
---
R
L
-
T
S
G
Y
-
L
-----------------
P
E
----
A
E
I
V
-
F
-
L
D
E
I
W
K
A
G
P
A
----
I
L
N
T
L
L
T
A
I
N
E
R
Q
-------
F
R
---------------
N
G
-----
A
H
V
E
K
I
P
M
R
L
-
L
V
A
A
S
N
E
L
P
-
E
A
D
-
S
S
L
E
A
L
Y
D
--
R
M
L
I
-
R
L
W
L
D
K
V
Q
D
K
A
-------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
71.04
18%
-150
- C2 -
3M6A
1
LON1_BACSU
A:
[107-263]
-----------------------------------------
K
G
P
I
L
C
L
A
-
G
--
P
P
G
V
G
K
T
S
L
A
K
-
S
I
A
K
S
L
-------
G
R
K
F
V
R
I
S
L
G
--------------------------------------------------------------------
G
R
-
I
I
Q
G
M
K
------
K
A
G
K
---
L
----
N
P
V
F
-
L
-
L
D
E
I
D
K
M
S
---------
A
M
L
E
V
L
D
P
E
Q
N
S
S
----
F
S
--------------
D
H
Y
-----
I
E
E
T
F
D
L
S
K
V
L
F
I
A
T
A
N
N
L
A
-----
T
I
P
G
P
L
R
D
--
R
M
E
I
-
I
-
N
I
A
G
Y
T
E
I
E
K
L
E
I
V
K
-------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
71.03
17%
-139
- C2 -
4YPN
-
?
A:
[347-492]
-----------------------------------------
K
A
P
I
L
V
L
V
-
G
--
P
P
G
V
G
K
T
S
L
G
R
-
S
I
A
R
S
M
N
-------
R
K
F
H
R
I
S
L
G
G
V
R
D
E
A
E
I
R
G
H
R
R
T
------
Y
I
-----------------------------------------
G
A
-
M
P
G
K
-
L
I
H
A
M
K
------
Q
V
G
---
V
I
----
N
P
V
I
-
L
-
L
D
E
I
D
K
M
S
S
D
WRG
D
P
A
S
A
M
L
E
V
L
D
P
E
Q
N
N
----
T
F
T
D
-------------
H
Y
L
-----
D
V
P
Y
-
D
L
S
K
V
F
F
I
T
T
A
N
T
L
Q
-----
T
I
P
R
P
L
L
D
--
R
M
E
V
-
I
-
E
I
P
G
------------------------------------------------------------------------------------------------------------------------------------------
11
Fugue
66.21
12%
-98
- C2 -
1FNN
2
?
A:
[2-389]
AIVVDDSV
F
S
P
S
Y
V
P
K
R
L
P
H
R
E
Q
Q
L
Q
Q
L
D
I
L
L
G
N
W
L
R
NPG
H
H
Y
P
R
A
T
L
L
-
G
--
R
P
G
T
G
K
T
V
T
L
R
-
K
L
W
E
L
Y
K
D
K
T
---
T
A
R
F
V
Y
I
N
G
F
I
Y
R
N
F
T
A
I
I
G
E
I
A
R
S
L
N
I
P
F
P
R
-
R
G
L
S
R
D
E
-
F
L
A
L
L
V
E
H
L
-
R
E
R
D
L
Y
M
-----
F
L
V
L
D
D
A
---
F
N
-
L
A
P
D
-
I
L
S
T
F
I
------
R
L
G
Q
E
A
D
K
LGAF
R
I
A
L
-
V
-
I
V
G
H
N
D
A
V
L
N
---
N
L
D
P
S
T
R
G
I
M
G
K
Y
V
I
R
F
S
P
Y
T
K
D
Q
--
I
F
D
I
L
L
D
R
A
K
A
G
L
A
EGSYS
E
D
I
L
Q
M
I
A
D
I
T
G
A
Q
T
P
L
D
T
N
-
R
G
D
A
R
L
A
I
D
I
L
Y
--
R
S
A
Y
-
A
-
A
Q
Q
N
G
R
K
H
I
A
P
E
D
V
R
K
S
S
K
E
V
L
----------
F
G
I
S
E
E
V
L
I
G
L
P
L
H
E
K
L
F
L
L
A
I
V
R
S
-
L
K
---
I
S
H
T
P
Y
I
T
F
G
D
A
E
E
S
Y
K
I
V
C
E
E
Y
G
-
E
R
P
R
V
H
S
Q
L
W
S
Y
L
N
D
L
R
E
K
G
I
V
E
T
R
Q
N
T
T
L
I
S
I
G
T
EP
L
D
T
L
E
A
V
I
T
K
L
I
K
E
E
L
R
13
Fugue
63.44
12%
-97
- C2 -
4MUB
2
?
A:
[1-259]
------------------------------
G
A
M
I
E
S
----
S
T
T
I
Q
V
I
S
A
-
G
--
L
P
R
T
G
-
T
K
S
L
K
-
N
A
L
E
I
I
Y
H
K
P
---
C
Y
H
M
F
E
I
I
F
N
K
Q
S
D
I
I
K
W
Q
N
L
I
H
D
------
S
H
-
M
I
T
T
L
T
T
-
K
T
I
A
I
Y
D
K
L
-
K
E
L
L
D
G
Y
-----
I
A
T
T
D
-
L
-----------
P
T
C
G
F
Y
------
K
D
L
M
N
I
Y
P
----
N
A
K
V
-
L
-
L
T
I
R
D
K
Y
D
W
L
---
H
S
L
R
K
V
V
L
P
K
S
N
D
P
-------------------------------------------------
W
K
-
L
K
I
E
E
G
D
K
V
L
G
L
--
N
S
D
F
-
Y
-
K
L
T
E
D
S
L
K
F
A
F
Q
K
D
D
L
N
F
D
D
D
Q
V
L
L
E
C
Y
D
E
Y
N
R
L
V
Q
E
T
-----
V
P
S
D
R
-
L
L
V
L
R
L
G
D
-
G
-----------
W
E
P
L
C
K
F
L
N
V
E
I
P
N
G
I
D
Y
P
C
V
N
S
H
H
Q
M
T
Q
L
T
E
Q
L
I
K
Y
K
S
L
D
A
I
I
H
M
F
P
D
L
I
---------------------
15
Fugue
59.39
14%
-64
- C2 -
1H65
2
TOC34_PEA
A:
[8-264]
--------
V
R
E
W
S
G
I
N
T
F
A
P
A
T
Q
T
K
L
L
E
L
L
G
N
L
K
Q
E
----
D
V
N
S
L
T
I
L
V
M
G
--
K
G
G
V
G
K
S
S
T
V
N
-
S
I
I
G
E
------------------
R
V
V
S
I
S
P
F
Q
S
E
G
P
R
------
P
V
M
V
S
R
S
R
A
G
-
F
T
L
N
I
I
D
T
---------------
P
G
L
I
-
E
---
G
G
-
Y
I
N
D
M
A
L
N
I
I
K
------
S
F
L
L
D
K
T
I
----
D
V
L
L
-
Y
-
V
D
R
L
D
A
Y
R
V
D
-------------
N
L
D
K
L
V
A
K
A
I
T
D
S
F
--
G
K
G
I
W
N
K
--------------------
A
I
V
A
L
T
H
A
Q
F
S
P
-
P
D
----
G
L
P
Y
D
E
--
F
F
S
K
-
R
-
S
E
A
L
L
Q
V
V
R
S
G
A
S
L
K
K
D
A
Q
A
S
D
I
P
V
V
L
I
E
N
S
G
R
C
N
K
N
D
S
----------------
D
E
-
K
V
---
L
P
N
G
I
A
W
I
P
H
L
V
Q
T
I
T
E
V
A
L
N
K
S
E
S
I
F
V
-----
D
K
N
L
I
D
K
L
A
A
A
D
----------------------------------
7
Fugue
53.38
17%
-59
- C2 -
4F3V
6
ECCA1_MYCTU
A:
[1-275]
-----------
G
H
M
T
D
R
L
A
S
L
F
E
S
A
V
S
M
L
P
M
-
S
E
A
R
----
S
L
D
L
F
T
E
I
T
-
N
--
Y
D
E
S
A
----
C
D
-
A
W
I
G
R
I
R
C
G
D
---
T
---
D
R
V
T
L
F
R
A
W
Y
S
R
R
N
F
G
----------------
Q
L
S
G
-
S
V
Q
I
S
M
S
T
L
-
N
A
R
I
A
--------------------
I
G
G
L
-
Y
G
D
I
T
Y
------
P
V
T
S
P
L
A
I
----
T
M
G
F
-
A
-
A
C
E
A
A
Q
G
N
-------
Y
A
D
A
M
E
A
L
E
A
A
P
V
A
G
S
E
H
L
V
A
W
--
M
K
A
V
V
Y
G
A
A
--
E
R
W
-----
T
D
V
I
D
Q
V
K
S
A
G
K
W
P
D
K
F
L
A
G
-
A
A
G
V
A
H
G
V
A
A
A
N
--
L
A
L
F
-
T
-
E
A
E
-
R
R
L
T
E
A
N
D
S
-------
P
A
G
E
A
C
A
R
A
I
A
W
Y
L
A
M
A
R
R
S
Q
G
N
E
S
A
A
V
A
L
L
E
W
L
Q
T
T
-
H
P
----------
E
P
K
V
A
A
A
L
K
D
P
S
Y
R
L
K
T
T
----
T
A
E
Q
I
A
S
R
A
D
P
W
D
P
G
S
V
V
--------------------------------
8
Fugue
51.74
16%
-97
- C2 -
1Y63
15
?
A:
[6-179]
----------------------------------
E
Q
----
P
K
G
I
N
I
L
I
T
-
G
--
T
P
G
T
G
K
T
S
M
A
E
-
M
I
A
A
E
-----------------
L
D
G
F
Q
H
L
E
V
G
K
L
V
K
E
------
N
H
-
F
Y
T
E
T
H
I
-
I
E
E
K
D
E
D
R
L
-
L
D
F
M
E
P
I
MVS
R
G
N
H
V
V
D
-
Y
HSS
E
L
-
F
P
E
R
-
W
F
H
M
V
V
V
L
H
T
S
T
E
V
L
F
E
R
L
T
----
K
R
Q
Y
-
S
-
E
A
K
R
A
E
N
M
E
A
---
E
I
Q
C
I
C
E
E
E
A
R
D
A
Y
E
D
D
I
V
L
V
R
E
N
--
D
T
L
E
Q
M
A
A
T
V
E
E
I
R
-----
E
R
V
E
V
L
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
51.03
28%
-104
- C1 -
2O1B
1
?
A:
[165-229]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
H
Y
L
P
D
W
S
K
---
V
D
S
Q
I
I
D
K
T
K
L
I
Y
L
----
T
Y
P
N
N
P
T
G
S
T
A
T
K
E
V
F
D
E
A
I
A
K
F
K
G
T
D
T
K
I
V
H
D
F
A
Y
G
A
F
G
F
D
-------------------
6
Fugue
42.13
17%
-66
- C2 -
3B85
5
?
A:
[4-208]
----------------------
V
I
R
P
K
T
L
G
Q
K
H
Y
V
D
----
A
I
D
T
N
T
I
V
F
-
G
L
G
P
A
G
S
G
K
T
-
Y
L
A
M
A
K
A
V
Q
A
L
Q
S
K
QVS
R
I
I
L
T
R
P
A
V
E
A
G
E
K
L
G
F
L
P
G
D
P
Y
L
------
R
P
-
L
H
D
A
L
R
D
M
V
E
P
E
V
I
P
K
L
M
E
A
G
I
V
E
V
-----
A
P
L
-------
A
Y
M
R
G
R
T
-
L
N
D
A
F
V
------
I
L
D
E
A
Q
N
T
----
T
P
A
Q
M
K
M
F
L
T
R
L
G
F
G
S
K
M
--
V
V
T
G
D
G
L
R
L
V
R
H
I
L
R
G
V
D
D
V
H
F
S
E
L
T
S
S
D
V
V
R
H
Q
L
V
G
H
I
V
-----
D
A
Y
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
38.39
33%
-82
- C2 -
5FTJ
2
TERA_HUMAN
A:
[615-683]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
V
F
I
I
G
A
T
N
R
P
D
-----
I
I
D
P
A
I
L
R
PG
R
L
D
Q
-
L
I
Y
I
P
L
P
D
E
K
S
R
V
A
I
L
K
A
N
L
R
K
--------------------------------------------------------------------------------------------------------------------------
27
HHSearch
38.31
26%
-120
- C2 -
3WHK
1
PAN_PYRFU (first)
A:
[49-89]
----------------------------------------
D
P
P
K
G
V
L
L
Y
-
G
--
P
P
G
C
G
K
T
L
M
A
K
-
A
I
A
H
E
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
37.17
31%
-143
- C1 -
2I00
-
?
A:
[244-294]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
Y
L
N
Q
-
E
A
R
N
G
L
W
N
F
I
T
A
H
F
S
M
V
Y
W
V
K
G
D
I
Y
K
N
E
P
L
A
F
L
L
E
D
S
Q
I
K
E
S
I
E
P
Y
--------------------------------------
18
HHSearch
32.40
32%
-91
- C2 -
4CR2
-
PRS6B_YEAST
K:
[203-230]
-----------------------------------
I
----
D
P
P
R
G
V
L
L
Y
-
G
--
P
P
G
T
G
K
T
M
L
V
K
-
A
V
A
N
S
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
27.25
16%
-72
- C2 -
5FTJ
2
TERA_HUMAN
A:
[339-405]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
V
I
V
M
A
A
T
N
R
P
N
-----
S
I
D
P
A
L
R
R
FG
R
F
D
R
-
E
V
D
I
G
I
P
D
A
T
G
R
L
E
I
L
Q
I
H
T
----------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
26.98
28%
-40
- C1 -
1ODF
2
TDA10_YEAST
A:
[97-156]
--------------------------------------------------
G
--
L
P
G
T
H
D
M
K
L
L
Q
-
E
V
L
N
T
I
F
N
---------
Q
D
T
V
V
L
P
K
Y
D
K
S
Q
F
K
G
E
G
D
R
------
C
P
-
T
G
Q
K
I
K
L
-
P
V
D
I
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
26.87
33%
-35
* C1 *
2M8G
-
?
X:
[429-477]
-----------
S
S
E
L
P
E
L
L
R
K
R
E
R
K
T
G
D
L
P
K
F
--
I
E
----
E
T
E
K
K
R
I
I
E
-
A
--
L
E
K
T
G
---
Y
V
K
-
S
R
A
A
K
L
L
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
24.68
16%
-72
- C2 -
4CR2
-
PRS4_YEAST
I:
[320-365]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
V
K
V
I
M
A
T
N
K
I
E
-----
T
L
D
P
A
L
I
R
PG
R
I
D
R
-
K
I
L
F
E
N
P
D
L
S
T
K
K
K
I
L
G
I
H
-----------------------------------------------------------------------------------------------------------------------------