@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu07130: (2016-06-11 )
MFHISTLDQIKIAYIGGGSQGWARSLMSDLSIDERMSGTVALYDLDFEAAQKNEVIGNHSGNGRWRYEAVSTLKKALSAADIVIISILPGSLDDMEVDVHLPERCGIYQSVGDTVGPGGIIRGLRAVPIFAEIARAIRDYAPESWVINYTNPMSVCTRVLYKVFPGIKAIGCCHEVFGTQKLLAEMVTERLGIEVPRREDIRVNVLGINHFTWITKASYRHIDLLPIFREFSAHYGESGYELEGECWRDSVFCSAHRVAFDLFETYGAIPAAGDRHLAEFLPGPYLKQPEVWKFHLTPISFRKQDRAEKRQETERLIVQQRGVAEKASGEEGVNIIAALLGLGELVTNVNMPNQGQVLNLPIQAIVETNAFITRNRVQPILSGALPKGVEMLAARHISNQEAVADAGLTKDTGLAFQAFLNDPLVQIDRSDAEQLFNDMLQCIMQS
Atome Classification :
(20 SA)
.........10........20.......---.--30-.-......--.-.40........--50...--....---.60--.--..-..----..----.70..--......80........--------90------.........100......-----.110..-.......120......---.130.......140.......150.......160.--.--.....170-..--.....180.......190....---...200.......---210.......220....-....230....---...240....--.--..250-------.......260---..-......270.......280.....--.----.290--------------..--...-----..---300--....---....-310----......-----.--------.-----320-.--.----.-..------------....330.......-----340......------.350.....--..360.......370----........380..-.....390.-...-....--400.......410.......420.......430.......440....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MFHIS
T
L
D
Q
I
K
I
A
Y
IGGGS
Q
G
W
A
R
S
L
M
S
---D--L--
S
-
I
D
E
RMS--G-
T
V
A
L
Y
DLDFEA--AQKN
E
--
V
IGN---HSG--N--
G
R
-
W
R
----
Y
E
----
A
V
S
T
L
--
K
K
A
LSAA
D
I
V
I
I
S
ILP--------G-------SLDD
M
E
V
D
V
HL
P
E
RC
G
I
Y
-----
Q
S
--VG-DTVG
P
G
G
I
I
R
GLRAV
P
---
I
F
A
E
I
A
R
A
I
R
DYAPE
S
W
V
I
NYT
N
P
M
S
V
C
T
R
V
L
Y
K
V--F--P
G
I
K
A
I
G
C
-
C
H
--
E
V
F
G
T
Q
K
L
L
A
E
M
V
T
E
R
LGIEVP---RRE
D
I
R
V
N
V
L
GIN---
H
F
T
W
I
TKASYRH-I
D
L
L
-
P
I
F
R
E
F
S
A
HYG---ESGYELE
G
E
C--W--RD
S
V
F
-------
C
S
A
H
R
V
A
F
D
----
L
F
-
E
T
YGAIPAAG
D
R
H
L
A
E
FLPGPYLK--Q----P
E
V
W
--------------
K
F
--HLT-----PI---
S
F
---
R
K
Q
D
---
R
A
E
K
-
R
Q
-----
E
T
E
R
L
I
-----
V
--------
Q
-----Q---R--G----V-AE------------KASGE
E
G
V
N
I
I
A
A
L
-----
L
G
L
G
E
L
V
T
N------VNMPNQG
Q
V
--
L
N
L
P
I
Q
A
IVETN
A
F
-----
I
TR
N
R
V
Q
P
I
L
SGA-L
P
K
G
V
E
M
-
L
-
A
A
R
-HIS
N
--
Q
E
A
V
ADAGLTKDT
G
L
A
F
Q
A
F
LNDP
L
V
QI
D
R
S
D
A
E
Q
L
F
N
D
M
L
Q
C
I
MQS
1
PsiBlast_PDB
82.22
97%
-110
* C2 *
3FEF
3
LPLD_BACSU
A:
[3-436]
------
L
D
Q
I
K
I
A
Y
I
G
G
G
S
Q
G
W
A
R
S
L
M
S
---
D
--
L
--
S
-
I
D
E
R
M
S
--
G
-
T
V
A
L
Y
D
L
D
F
E
A
--
A
Q
K
N
E
--
V
I
G
N
---
H
S
G
--
N
--
G
R
-
W
R
----
Y
E
----
A
V
S
T
L
--
K
K
A
L
S
A
A
D
I
V
I
I
S
I
L
P
--------
G
-------
S
L
D
D
M
E
V
D
V
H
L
P
E
R
C
G
I
Y
-----
Q
S
--
V
G
-
D
T
V
G
P
G
G
I
I
R
G
L
R
A
V
P
---
I
F
A
E
I
A
R
A
I
R
D
Y
A
P
E
S
W
V
I
N
Y
T
N
P
M
S
V
C
T
R
V
L
Y
K
V
--
F
--
P
G
I
K
A
I
G
C
-
C
H
--
E
V
F
G
T
Q
K
L
L
A
E
M
V
T
E
R
L
G
I
E
V
P
---
R
R
E
D
I
R
V
N
V
L
G
I
N
---
H
F
T
W
I
T
K
A
S
Y
R
H
-
I
D
L
L
-
P
I
F
R
E
F
S
A
H
Y
G
---
E
S
G
Y
E
L
E
G
E
C
--
W
--
R
D
S
V
F
-------
C
S
A
H
R
V
A
F
D
----
L
F
-
E
T
Y
G
A
I
P
A
A
G
D
R
H
L
A
E
F
L
P
G
P
Y
L
K
--
Q
----
P
E
V
W
--------------
K
F
--
H
L
T
-----
P
I
---
S
F
---
R
K
Q
D
---
R
A
E
K
-
R
Q
-----
E
T
E
R
L
I
-----
V
--------
Q
-----
Q
---
R
--
G
----
V
-
A
E
------------
K
A
S
G
E
E
G
V
N
I
I
A
A
L
-----
L
G
L
G
E
L
V
T
N
------
V
N
M
P
N
Q
G
Q
V
--
L
N
L
P
I
Q
A
I
V
E
T
N
A
F
-----
I
T
R
N
R
V
Q
P
I
L
S
G
A
-
L
P
K
G
V
E
M
-
L
-
A
A
R
-
H
I
S
N
--
Q
E
A
V
A
D
A
G
L
T
K
D
T
G
L
A
F
Q
A
F
L
N
D
P
L
V
Q
I
D
R
S
D
A
E
Q
L
F
N
D
M
L
------
61
HHSearch
78.59
94%
-109
- C2 -
3FEF
3
LPLD_BACSU
A:
[3-436]
------
L
D
Q
I
K
I
A
Y
I
G
G
G
S
Q
G
W
A
R
S
L
M
S
---
D
--
L
--
S
-
I
D
E
R
M
S
--
G
-
T
V
A
L
Y
D
L
D
F
E
A
--
A
Q
K
N
E
--
V
I
G
N
---
H
S
G
-----
N
G
R
W
R
----
Y
E
----
A
V
S
T
L
--
K
K
A
L
S
A
A
D
I
V
I
I
S
I
L
P
--------
G
-------
S
L
D
D
M
E
V
D
V
H
L
P
E
R
C
G
I
Y
-----
Q
S
--
V
G
-
D
T
V
G
P
G
G
I
I
R
G
L
R
A
V
P
---
I
F
A
E
I
A
R
A
I
R
D
Y
A
P
E
S
W
V
I
N
Y
T
N
P
M
S
V
C
T
R
V
L
Y
K
V
--
F
--
P
G
I
K
A
I
G
C
-
C
H
--
E
V
F
G
T
Q
K
L
L
A
E
M
V
T
E
R
L
--
G
I
E
VPR
R
-
E
D
I
R
V
N
V
L
G
I
N
---
H
F
T
W
I
T
K
A
S
Y
-
R
H
I
D
L
L
-
P
I
F
R
E
F
S
A
H
Y
G
---
E
S
G
Y
E
L
E
G
E
C
--
W
--
R
D
S
V
F
-------
C
S
A
H
R
V
A
F
D
----
L
F
-
E
T
Y
G
A
I
P
A
A
G
D
R
H
L
A
E
F
L
P
-
G
P
Y
L
--
K
Q---
P
E
V
W
--------------
K
F
--
H
L
T
P
I
S
F
R
K
----
Q
D
---
R
A
E
K
---
R
Q
E
T
-
E
R
L
----
I
V
Q
Q
----------------------
R
------
G
----
V
-
A
E
------------
K
A
S
G
E
E
G
V
N
I
I
A
A
L
-----
L
G
L
G
E
L
V
T
N
------
V
N
M
P
N
Q
G
Q
V
--
L
N
L
P
I
Q
A
I
V
E
T
N
A
F
-----
I
T
R
N
R
V
Q
P
I
L
S
G
A
-
L
P
K
G
V
E
M
-
L
-
A
A
R
-
H
I
S
N
--
Q
E
A
V
A
D
A
G
L
T
K
D
T
G
L
A
F
Q
A
F
L
N
D
P
L
V
Q
I
D
R
S
D
A
E
Q
L
F
N
D
M
L
------
65
HHSearch
51.75
23%
-112
- C2 -
1UP7
3
BGLT_THEMA
A:
[1-411]
-------
R
H
M
R
I
A
V
I
G
G
G
S
S
Y
T
P
--
E
L
V
K
G
-
L
--
L
--
D
-
I
S
E
D
V
R
--
I
D
E
V
I
F
Y
D
I
D
E
E
K
--
Q
K
I
V
V
--
D
F
V
K
---
R
L
V
-----
K
D
R
F
K
----
V
L
----
I
S
D
T
F
--
E
G
A
V
V
D
A
K
Y
V
I
F
Q
F
R
P
--------
G
-------
G
L
K
G
R
E
N
D
E
G
I
P
L
K
Y
G
L
I
---------
G
Q
-
E
T
T
G
V
G
G
F
S
A
A
L
R
A
F
P
---
I
V
E
E
Y
V
D
T
V
R
K
T
-
S
N
A
T
I
V
N
F
T
N
P
S
G
H
I
T
E
F
V
R
N
Y
--
L
--
E
Y
E
K
F
I
G
L
-
C
N
--
V
P
I
N
F
I
R
E
I
A
E
M
F
------
S
A
R
---
L
-
E
D
V
F
L
K
Y
Y
G
L
N
---
H
L
S
F
I
E
K
V
F
V
-
K
G
E
D
V
T
-
E
K
V
F
E
N
L
K
L
K
-------------------------------
I
P
D
E
D
F
P
T
W
----
F
Y
-
D
S
V
R
L
I
V
N
-------
P
Y
L
R
-
Y
Y
L
M
--
E
K
K
M
-
F
K
K
I
--------------
S
-----
T
-----
H
----
E
L
---
R
A
R
E
---
V
M
K
I
-
E
K
E
----
L
F
E
K
Y
R
-----
T
--------
A
-----
V
EIP
E
--
E
LTK-
R
-
G
G
------------
S
M
Y
S
T
A
A
A
H
L
I
R
D
L
-----
E
T
D
E
G
K
I
H
I
------
V
N
T
R
N
N
G
S
I
--
E
N
L
P
D
D
Y
V
L
E
I
P
C
Y
-----
V
R
S
G
R
V
H
T
L
S
Q
G
K
-
G
D
H
F
A
L
S
-
F
-
I
H
A
-
V
K
M
Y
--
E
R
L
T
I
E
A
Y
L
K
R
S
K
K
L
A
L
K
A
L
L
S
H
P
L
G
P
-
D
V
E
D
A
K
D
L
L
E
E
I
L
E
A
N
R
--
2
PsiBlast_PDB
51.55
25%
-107
- C2 -
1S6Y
-
?
A:
[4-432]
--------
R
L
K
I
A
T
I
G
G
G
S
S
-
Y
T
P
E
L
V
E
---
G
--
L
I
K
R
-
Y
H
E
L
P
V
--
G
-
E
L
W
L
V
D
I
P
-
E
G
--
K
E
K
L
E
--
I
V
G
A
---
L
A
K
--
R
--
M
V
-
E
K
A
G
V
P
I
E
----
I
H
L
T
L
D
R
R
R
A
L
D
G
A
D
F
V
T
T
Q
F
R
V
--------
G
-------
G
L
E
A
R
A
K
D
E
R
I
P
L
K
Y
G
V
I
-----
G
Q
-----
E
T
N
G
P
G
G
L
F
K
G
L
R
T
I
P
---
V
I
L
D
I
I
R
D
M
E
E
L
C
P
D
A
W
L
I
N
F
T
N
P
A
G
M
V
T
E
A
V
L
R
Y
--
T
--
K
Q
E
K
V
V
G
L
-
C
N
--
V
P
I
G
M
R
M
G
V
A
K
L
----
L
G
V
D
A
D
---
R
---
V
H
I
D
F
A
G
L
N
---
H
M
V
F
G
L
H
V
Y
L
D
G
-
V
E
V
T
-
E
K
V
I
D
L
V
A
H
P
--------------LG
W
--
E
P
D
F
L
K
G
L
K
V
L
P
C
P
Y
H
R
Y
Y
F
Q
T
D
K
M
L
A
-
E
E
L
E
A
A
K
T
K
G
T
R
--
A
E
V
-----
V
Q
--
Q
----
L
E
K
E
--------------
L
F
--
E
L
------------
Y
---
K
D
P
----------------------------------------------
R
--
G
----
G
-
A
Y
------------
Y
S
--
D
A
A
C
S
L
I
S
S
I
-----
Y
N
D
K
R
D
I
Q
P
------
V
N
T
R
N
N
G
A
I
--
A
S
I
S
A
E
S
A
V
E
V
N
C
V
-----
I
T
K
D
G
P
K
P
I
A
V
G
D
-
L
P
V
A
V
R
G
-
L
-
V
Q
Q
-
I
K
S
F
--
E
R
V
A
A
E
A
A
V
T
G
D
Y
Q
T
A
L
V
A
M
T
I
N
P
L
V
P
S
D
-
T
I
A
K
Q
I
L
D
E
M
L
E
A
----
64
HHSearch
51.45
18%
-104
- C2 -
3U95
1
?
A:
[1-460]
---------
M
K
I
S
I
V
G
A
G
S
V
R
F
A
--
L
Q
L
V
E
-
D
--
I
--
A
-
Q
T
D
E
L
S
RE
D
T
H
I
Y
L
M
D
V
H
E
R
R
--
L
N
A
S
Y
--
I
L
A
R
---
K
Y
V
E
E
L
--
N
S
P
V
K
----
V
V
----
K
T
E
S
L
--
D
E
A
I
E
G
A
D
F
I
I
N
T
A
Y
P
--------
Y
D
PRYHDS
G
S
Q
R
W
D
E
V
T
K
V
G
E
K
H
G
Y
Y
-----
R
G
ID
S
Q
-
E
L
N
M
V
S
T
Y
T
Y
V
L
S
S
Y
P
D
V
K
L
A
L
E
I
A
E
K
M
K
K
M
A
P
K
A
Y
L
M
Q
T
A
N
P
V
F
E
I
T
Q
A
V
R
R
W
-----
T
G
A
N
I
I
G
F
-
C
H
--
G
V
A
-
G
V
Y
E
V
F
E
R
L
------
G
L
D
---
P
-
E
E
V
D
W
Q
V
A
G
V
N
---
H
G
I
W
L
N
R
F
R
-
Y
R
G
K
D
A
Y
-
P
L
L
D
E
W
I
E
K
E
L
---
S
K
----
W
E
P
K
------
N
P
W
D
-------
T
Q
M
S
P
A
A
M
D
----
M
Y
-
R
F
Y
G
M
L
P
I
G
D
T
-
V
R
N
G
T
W
K
-
Y
H
Y
N
--
L
E
T
--
K
K
K
W
--------------
F
R
--
R
F
G
-----
G
I
DNE
V
E
---
R
P
K
F
H
E
H
L
R
R
A
-
R
E
R
----
L
I
K
L
A
E
-----
E
V
Q
E
N
PHLK
I
T----
E
KHP
E
--
I
----
F
P
K
G
------------
R
L
S
G
E
Q
H
I
P
F
I
N
A
I
-----
A
N
N
K
R
V
R
L
F
------
L
N
V
E
N
Q
G
A
L
--
K
D
F
P
D
D
L
V
M
E
L
P
V
W
-----
V
D
S
S
G
I
H
R
E
K
V
E
P
D
L
T
H
R
I
K
I
-
F
Y
L
W
P
-
R
I
L
R
--
T
E
W
N
L
E
A
F
I
S
R
D
R
K
V
L
E
E
I
L
I
R
D
P
R
T
K
-
S
Y
E
Q
V
V
K
V
L
D
E
I
L
S
L
P
F
N
-
8
PsiBlast_PDB
50.48
22%
-99
- C2 -
1VJT
1
?
A:
[14-451]
----------
K
I
S
I
I
G
A
G
S
V
R
F
A
L
Q
L
V
G
---
D
--
I
--
A
-
Q
T
E
E
L
S
R-
E
-
D
T
H
I
Y
M
M
D
V
H
E
--
R
R
L
N
A
S
Y
I
L
A
R
K
Y
V
E
E
L
--
N
--
S
P
-
V
K
----
I
V
----
K
T
S
S
L
--
D
E
A
I
D
G
A
D
F
I
I
N
T
A
Y
P
Y
D
PRYHDS
G
-------
S
Q
R
W
D
E
V
-
T
K
V
G
E
K
H
G
Y
Y
RGIDS
Q
E
--
L
N
-
M
V
S
T
Y
T
Y
V
L
S
S
Y
P
D
M
K
---
L
A
L
E
I
A
E
K
M
K
K
M
A
P
K
A
Y
L
M
Q
T
A
N
P
V
F
E
I
T
Q
A
V
-
R
R
--
W
--
T
G
A
N
I
V
G
F
-
C
H
--
G
V
A
G
V
Y
E
-----
V
F
E
K
L
D
L
D
P
------
E
E
V
D
W
Q
V
A
G
V
N
---
H
G
I
W
L
N
R
F
R
Y
R
G
-
E
D
A
Y
-
P
L
L
D
E
W
I
E
------
K
K
L
P
E
W
E
P
K
N
--
P
--
W
D
T
Q
M
-------
S
P
A
---
A
M
D
----
M
Y
-
K
F
Y
G
M
L
P
I
G
D
T
V
R
N
G
S
W
K
Y
H
Y
N
L
E
--
T
----
K
K
K
W
--------------
F
G
--
K
F
G
-----
G
I
---
D
N
EV
E
R
P
K
F
---
H
E
Q
L
-
R
R
-----
A
R
E
R
L
I
K
L
A
E
E
V
--------
Q
-----
Q
---
N
--
P
----
G
-
M
K
LTEEHPEIFPKG
K
L
S
G
E
Q
H
I
P
F
I
N
A
I
-----
A
N
N
K
R
V
R
L
F
------
L
N
V
E
N
Q
G
T
L
--
K
D
F
P
D
D
V
V
M
E
L
P
V
W
V
D
CC
G
I
H
R
E
K
V
E
P
D
L
T
H
R
-
I
--
K
I
F
Y
-
L
-
W
P
R
--
I
L
R
--
M
E
W
N
L
E
A
Y
I
S
R
D
R
K
V
L
E
E
I
L
I
R
D
P
-----------------------
66
HHSearch
50.23
21%
-110
- C2 -
1S6Y
-
?
A:
[4-434]
--------
R
L
K
I
A
T
I
G
G
G
S
S
Y
T
P
E
L
V
E
G
---
L
--
I
--
K
-
R
Y
H
E
L
P
--
V
G
E
L
W
L
V
D
I
P
E
G
K
E
K
L
E
I
V
G
--
A
L
A
K
---
R
M
V
E
K
A
--
G
V
P
I
E
----
I
H
----
L
T
L
D
R
--
R
R
A
L
D
G
A
D
F
V
T
T
Q
F
R
V
--------
G
-------
G
L
E
A
R
A
K
D
E
R
I
P
L
K
Y
G
V
I
---------
G
Q
-
E
T
N
G
P
G
G
L
F
K
G
L
R
T
I
P
---
V
I
L
D
I
I
R
D
M
E
E
L
C
P
D
A
W
L
I
N
F
T
N
P
A
G
M
V
T
E
A
V
L
R
Y
--
T
--
K
Q
E
K
V
V
G
L
-
C
N
--
V
P
I
G
M
R
M
G
V
A
K
L
L
------
G
V
D
---
A
-
D
R
V
H
I
D
F
A
G
L
N
---
H
M
V
F
G
L
H
V
Y
L
-
D
G
V
E
V
T
-
E
K
V
I
D
L
V
A
H
P
----------------------------------
L
G
W
E
P
D
----
F
L
-
K
G
L
K
V
L
P
C
-------
P
Y
H
R
-
Y
Y
F
Q
--
T
D
K
M
-
L
A
E
E
--------------
L
E
--
A
A
K
-----
T
K
---
G
T
---
R
A
E
V
---
V
Q
Q
L
-
E
K
E
----
L
F
E
L
Y
K
-----
D
--------
P
------------------R
G
G
------------
A
Y
Y
S
D
A
A
C
S
L
I
S
S
I
-----
Y
N
D
K
R
D
I
Q
P
------
V
N
T
R
N
N
G
A
I
--
A
S
I
S
A
E
S
A
V
E
V
N
C
V
-----
I
T
K
D
G
P
K
P
I
A
V
G
D
-
L
P
V
A
V
R
G
-
L
-
V
Q
Q
-
I
K
S
F
--
E
R
V
A
A
E
A
A
V
T
G
D
Y
Q
T
A
L
V
A
M
T
I
N
P
L
V
P
-
S
D
T
I
A
K
Q
I
L
D
E
M
L
E
A
H
K
--
7
PsiBlast_PDB
49.91
22%
-108
- C2 -
3U95
1
?
A:
[1-439]
---------
M
K
I
S
I
V
G
A
G
S
V
R
F
A
L
Q
L
V
E
---
D
--
I
--
A
Q
T
D
E
L
S
R
--
E
-
D
T
H
I
Y
L
M
D
V
H
E
--
R
R
L
N
A
S
Y
I
L
A
R
K
Y
V
E
E
L
--
N
--
S
P
-
V
K
----
V
V
----
K
T
E
S
L
--
D
E
A
I
E
G
A
D
F
I
I
N
T
A
Y
P
Y
D
PRYHDS
G
-------
S
Q
R
W
D
E
V
-
T
K
V
G
E
K
H
G
Y
Y
RGIDS
Q
E
--
L
N
-
M
V
S
T
Y
T
Y
V
L
S
S
Y
P
D
V
K
---
L
A
L
E
I
A
E
K
M
K
K
M
A
P
K
A
Y
L
M
Q
T
A
N
P
V
F
E
I
T
Q
A
V
R
R
---
W
--
T
G
A
N
I
I
G
F
-
C
H
--
G
V
A
G
V
Y
E
-----
V
F
E
R
L
G
L
D
P
------
E
E
V
D
W
Q
V
A
G
V
N
---
H
G
I
W
L
N
R
F
R
Y
R
G
-
K
D
A
Y
-
P
L
L
D
E
W
-----------
I
E
K
E
L
S
K
--
W
EP
K
N
P
W
D
-------
T
Q
M
S
P
A
A
M
D
----
M
Y
-
R
F
Y
G
M
L
P
I
G
D
T
V
R
N
G
T
W
K
Y
H
Y
N
L
E
--
T
----
K
K
K
W
FRRFGGIDNEV
E
R
P
K
F
H
E
H
L
R
-----
R
A
---
R
E
---
R
L
I
K
---
L
A
E
E
-
V
Q
-----
E
N
P
H
L
K
-----
I
--------
T
-----
E
---
K
--
H
PEIF
P
-
K
G
------------
R
L
S
G
E
Q
H
I
P
F
I
N
A
I
-----
A
N
N
K
R
V
R
L
F
------
L
N
V
E
N
Q
G
A
L
--
K
D
F
P
D
D
L
V
M
E
L
P
V
W
V
D
SS
G
I
H
R
E
K
V
E
P
D
L
T
H
R
-
I
--
K
I
F
Y
-
L
-
W
P
R
--
I
L
R
--
T
E
W
N
L
E
A
F
I
S
R
D
R
K
V
L
E
E
I
L
I
R
D
P
-----------------------
63
HHSearch
49.36
21%
-93
- C2 -
1U8X
3
GLVA_BACSU
X:
[26-458]
------
K
K
S
F
S
I
V
I
A
G
G
G
S
T
F
T
P
--
G
I
V
---
L
ML
L
--
D
-
H
L
E
E
F
P
--
I
R
K
L
K
L
Y
D
N
D
K
E
R
--
Q
D
R
I
A
--
G
A
C
D
---
V
F
I
--
R
EK
A
P
D
I
E
----
F
A
----
A
T
T
D
P
--
E
E
A
F
T
D
V
D
F
V
M
A
H
I
R
V
--------
G
-------
K
Y
A
M
R
A
L
D
E
Q
I
P
L
K
Y
G
V
V
---------
G
Q
-
E
T
C
G
P
G
G
I
A
Y
G
M
R
S
I
G
---
G
V
L
E
I
L
D
Y
M
E
K
Y
S
P
D
A
W
M
L
N
Y
S
N
P
A
A
I
V
A
E
A
T
R
R
L
--
R
--
P
N
S
K
I
L
N
I
-
C
D
--
M
P
V
G
I
E
D
R
M
A
Q
I
L
------
G
L
S
S--
R
-
K
E
M
K
V
R
Y
Y
G
L
N
---
H
F
G
W
W
T
S
I
Q
D
Q
E
G
N
D
L
M
-
P
K
L
K
E
H
V
S
Q
Y
G
---
Y
I
P
K
T
----
S
--
W
--------------
N
D
T
F
A
K
A
R
D
----
V
Q
A
A
D
P
D
T
L
P
N
-------
T
Y
L
Q
-
Y
Y
L
F
--
P
DDM-
V
K
K
S
--------------
N
-----
P
-----
N
----
H
T
---
R
A
N
E
---
V
M
E
G
R
E
A
F----
I
F
S
Q
C
D
-----
M
--------
I
TREQS
S
---
E
NS
E
----
I
-
K
I
------------
D
D
H
A
S
Y
I
V
D
L
A
R
A
I
-----
A
Y
N
T
G
E
R
M
L
------
L
I
V
E
N
N
G
A
I
--
A
N
F
D
P
T
A
M
V
E
V
P
C
I
-----
V
G
S
N
G
P
E
P
I
T
V
G
T
-
I
P
Q
F
Q
K
G
-
L
-
M
E
Q
-
Q
V
S
V
--
E
K
L
T
V
E
A
W
A
E
K
S
F
Q
K
L
W
Q
A
L
I
L
S
K
T
V
P
-
N
A
R
V
A
R
L
I
L
E
D
L
V
E
A
N
K
--
4
PsiBlast_PDB
48.83
24%
-102
- C2 -
1UP7
3
BGLT_THEMA
A:
[2-409]
--------
H
M
R
I
A
V
I
G
G
G
S
-
S
Y
T
P
E
L
V
K
G
L
L
D
--
I
--
S
-
E
D
V
R
I
D
----
E
V
I
F
Y
D
I
D
E
E
K
--
Q
K
I
V
V
--
D
F
V
K
---
R
L
V
--
K
--
D
R
-
F
K
----
V
L
----
I
S
D
T
F
--
E
G
A
V
V
D
A
K
Y
V
I
F
Q
F
R
P
--------
G
-------
G
L
K
G
R
E
N
D
E
G
I
P
L
K
Y
G
L
----------
I
G
Q
E
T
T
G
V
G
G
F
S
A
A
L
R
A
F
P
---
I
V
E
E
Y
V
D
T
V
R
K
-
T
S
N
A
T
I
V
N
F
T
N
P
S
G
H
I
T
E
F
V
R
N
Y
--
L
--
E
Y
E
K
F
I
G
L
-
C
N
--
V
P
I
N
F
I
R
E
I
A
E
M
F
S
A
R
L
----------
E
D
V
F
L
K
Y
Y
G
L
N
---
H
L
S
F
I
E
K
V
F
V
K
G
-
E
D
V
T
E
K
V
F
E
N
L
K
L
K
------
I
P
D
E
D
F
P
T
W
--
F
--
Y
D
S
V
---------------------------------------
R
L
I
V
N
P
Y
L
R
--
Y
----
Y
L
M
E
--------------
K
K
--
M
F
K
-----
K
I
---
S
T
---
H
E
L
R
---
A
R
E
V
-
M
K
-----
I
E
K
E
L
F
-----
E
--------
K
-----
Y
---
R
--
T
----
A
-
V
E
IPEEL-------
T
K
R
G
G
S
M
Y
S
T
A
A
A
H
-----
L
-
I
R
D
L
E
T
D
E
G
K
I
H
I
V
N
T
R
N
N
G
S
I
--
E
N
L
P
D
D
Y
V
L
E
I
P
C
Y
-----
V
R
S
G
R
V
H
T
L
S
Q
G
----
K
G
D
H
F
A
L
-
S
F
I
-
H
A
V
K
M
Y
E
R
L
T
I
E
A
Y
L
K
R
S
K
K
L
A
L
K
A
L
L
S
H
P
L
G
P
-
D
V
E
D
A
K
D
L
L
E
E
I
L
E
A
----
5
PsiBlast_PDB
47.39
24%
-98
- C2 -
1UP4
-
BGLT_THEMA
A:
[2-407]
----------
R
I
A
V
I
G
G
G
S
S
-
Y
T
P
E
L
V
K
G
L
L
D
--
I
--
S
-
E
D
V
R
I
D
----
E
V
I
F
Y
D
I
D
E
E
K
--
Q
K
I
V
V
--
D
F
V
K
---
R
L
V
--
K
--
D
R
-
F
K
----
V
L
----
I
S
D
T
F
--
E
G
A
V
V
D
A
K
Y
V
I
F
Q
F
R
P
--------
G
-------
G
L
K
G
R
E
N
D
E
G
I
P
L
K
Y
G
L
I
-----
G
Q
-----
E
T
T
G
V
G
G
F
S
A
A
L
R
A
F
P
---
I
V
E
E
Y
V
D
T
V
R
K
-
T
S
N
A
T
I
V
N
F
T
N
P
S
G
H
I
T
E
F
V
R
N
Y
--
L
--
E
Y
E
K
F
I
G
L
-
C
N
--
V
P
I
N
F
I
R
E
I
A
E
M
F
S
A
R
L
----------
E
D
V
F
L
K
Y
Y
G
L
N
---
H
L
S
F
I
E
K
V
F
V
K
G
-
E
D
V
T
E
K
V
F
E
N
L
K
L
K
--------
D
E
D
F
P
T
W
--
F
--
Y
D
S
V
---------------------------------------
R
L
I
V
N
P
Y
L
R
--
Y
----
Y
L
M
E
--------------
K
K
--
M
F
K
-----
K
I
---
S
T
---
H
E
L
R
---
A
R
E
V
-
M
K
-----
I
E
K
E
L
F
-----
E
--------
K
-----
Y
---
R
--
T
----
A
-
V
E
IP
E
E
L
-------
T
K
R
G
G
S
M
Y
S
T
A
A
A
H
-----
L
-
I
R
D
L
E
T
D
E
G
K
I
H
I
V
N
T
R
N
N
G
S
I
--
E
N
L
P
D
D
Y
V
L
E
I
P
C
Y
-----
V
R
S
G
R
V
H
T
L
S
Q
G
----
K
G
D
H
F
A
L
-
S
F
I
-
H
A
V
K
M
Y
E
R
L
T
I
E
A
Y
L
K
R
S
K
K
L
A
L
K
A
L
L
S
H
P
L
G
P
-
D
V
E
D
A
K
D
L
L
E
E
I
L
E
A
----
6
PsiBlast_PDB
47.38
24%
-104
- C2 -
1UP6
6
BGLT_THEMA
A:
[3-408]
----------
R
I
A
V
I
G
G
G
S
S
-
Y
T
P
E
L
V
K
G
L
L
D
--
I
--
S
-
E
D
V
R
I
D
----
E
V
I
F
Y
D
I
D
E
E
K
--
Q
K
I
V
V
--
D
F
V
K
---
R
L
V
--
K
--
D
R
-
F
K
----
V
L
----
I
S
D
T
F
--
E
G
A
V
V
D
A
K
Y
V
I
F
Q
F
R
P
--------
G
-------
G
L
K
G
R
E
N
D
E
G
I
P
L
K
Y
G
L
I
-----
G
Q
-----
E
T
T
G
V
G
G
F
S
A
A
L
R
A
F
P
---
I
V
E
E
Y
V
D
T
V
R
K
-
T
S
N
A
T
I
V
N
F
T
N
P
S
G
H
I
T
E
F
V
R
N
Y
--
L
--
E
Y
E
K
F
I
G
L
-
C
N
--
V
P
I
N
F
I
R
E
I
A
E
M
F
S
A
R
L
----------
E
D
V
F
L
K
Y
Y
G
L
N
---
H
L
S
F
I
E
K
V
F
V
K
G
-
E
D
V
T
E
K
V
F
E
N
L
K
L
K
L
------
P
D
E
D
F
P
T
W
--
F
--
Y
D
S
V
---------------------------------------
R
L
I
V
N
P
Y
L
R
--
Y
----
Y
L
M
E
--------------
K
K
--
M
F
K
-----
K
I
---
S
T
---
H
E
L
R
---
A
R
E
V
-
M
K
-----
I
E
K
E
L
F
-----
E
--------
K
-----
Y
---
R
--
T
----
A
-
V
E
IP
E
E
L
-------
T
K
R
G
G
S
M
Y
S
T
A
A
A
H
-----
L
-
I
R
D
L
E
T
D
E
G
K
I
H
I
V
N
T
R
N
N
G
S
I
--
E
N
L
P
D
D
Y
V
L
E
I
P
C
Y
-----
V
R
S
G
R
V
H
T
L
S
Q
G
----
K
G
D
H
F
A
L
-
S
F
I
-
H
A
V
K
M
Y
E
R
L
T
I
E
A
Y
L
K
R
S
K
K
L
A
L
K
A
L
L
S
H
P
L
G
P
-
D
V
E
D
A
K
D
L
L
E
E
I
L
E
A
----
3
PsiBlast_PDB
42.82
23%
-79
- C2 -
1U8X
3
GLVA_BACSU
X:
[90-435]
---------------------------------------------------------------------------------------------
F
A
----
A
T
T
D
P
--
E
E
A
F
T
D
V
D
F
V
M
A
H
I
R
V
--------
G
-------
K
Y
A
M
R
A
L
D
E
Q
I
P
L
K
Y
G
V
----------
V
G
Q
E
T
C
G
P
G
G
I
A
Y
G
M
R
S
I
G
---
G
V
L
E
I
L
D
Y
M
E
K
Y
S
P
D
A
W
M
L
N
Y
S
N
P
A
A
I
V
A
E
A
T
R
R
L
--
R
--
P
N
S
K
I
L
N
I
-
C
D
--
M
P
V
G
I
E
D
R
M
A
Q
I
----
L
G
L
S
-----
S
R
K
E
M
K
V
R
Y
Y
G
L
N
---
H
F
G
W
W
T
S
I
Q
D
Q
E
G
N
D
L
M
-
P
K
L
K
E
H
V
S
Q
Y
G
YIP
K
T
-------
S
--
W
--
N
D
T
-
F
-------
A
K
A
R
D
V
-----------------
Q
A
A
D
---
P
D
T
L
P
N
T
Y
L
Q
--
Y
YLF-
P
D
D
M
--------------
V
K
--
K
S
N
-----
P
N
---
H
T
---
R
A
N
E
---
V
M
E
G
-
R
E
AFIFS
Q
C
D
M
I
T
-----
R
--------
E
-----
Q
---
S
--
S
----
E
-
N
S
------------
E
I
K
I
D
D
H
A
S
Y
I
V
D
L
ARAIA
Y
N
T
G
E
R
M
L
L
------
I
-
V
E
N
N
G
A
I
--
A
N
F
D
P
T
A
M
V
E
V
P
C
I
-----
V
G
S
N
G
P
E
P
I
T
V
G
T
-
I
P
Q
F
Q
K
G
-
L
-
M
E
Q
-
Q
V
S
V
--
E
K
L
T
V
E
A
W
A
E
K
S
F
Q
K
L
W
Q
A
L
I
--------------------------
83
HHSearch
41.57
18%
-142
- C2 -
1A5Z
7
LDH_THEMA
A:
[1-311]
---------
M
K
I
G
I
V
G
L
G
R
V
G
S
S
--
T
A
F
---
A
--
L
--
L
-
M
-
K
G
F
A
--
R
-
E
M
V
L
I
D
V
D
K
K
R
--
A
E
G
D
A
--
L
D
L
I
---
H
G
---
T
--
P
F
T
R
R
----
A
N
----
I
Y
A
G
D
--
Y
A
D
L
K
G
S
D
V
V
I
V
A
A
G
V
--------
P
-------
Q
K
P
G
E
T
R
L
-------
Q
L
-----------------------
L
G
R
N
A
R
---
V
M
K
E
I
A
R
N
V
S
K
Y
A
P
D
S
I
V
I
V
V
T
N
P
V
D
V
L
T
Y
F
F
L
K
E
S
G
M
--
D
P
R
K
V
F
G
S
-
G
T
V
L
D
T
A
R
L
R
T
L
I
A
Q
H
C
------
G
F
S
---
P
-
R
S
V
H
V
Y
V
I
G
E
H
---
G
D
------------
S
E
V
-
P
V
W
S
G
A
M
----------------------------------------------------
I
G
G
I
P
L
------
Q
N
M
C
Q
-
V
C
Q
K
--
C
D
S
K
I
L
E
N
F
-------------------
A
E
-----
K
T
---
K
R
---
A
A
Y
E
---
I
I
E
R
-------------------
K
--------
G
-----
A
-------------
T
H
------------
Y
A
I
A
L
A
V
A
D
I
V
E
S
I
-----
F
F
D
E
K
R
V
L
T
------
L
S
V
Y
L
E
D
Y
L
---
G
-
V
K
D
L
C
I
S
V
P
V
T
-----
L
G
K
H
G
V
E
R
I
L
E
L
N
-
L
N
E
E
E
L
E
-
A
-
F
R
K
-
S
A
S
I
--
L
K
N
A
I
N
E
I
T
A
E
E
-----------------------------------
70
HHSearch
40.99
18%
-134
- C2 -
3P7M
-
?
A:
[3-303]
------
M
A
R
K
K
I
T
L
V
G
A
G
N
I
G
G
T
--
L
A
H
---
L
--
A
--
L
-
I
-
K
Q
L
---
G
-
D
V
V
L
F
D
I
A
Q
G
M
--
P
N
G
K
A
L
-
D
L
L
Q
---
T
C
P
I-
E
--
G
V
D
F
K
----
V
R
----
G
T
N
D
Y
---
K
D
L
E
N
S
D
V
V
I
V
T
A
G
V
--------
P
-------
R
K
P
G
M
S
R
D
D
L
-------
L
-----------------------
G
I
N
I
K
---
V
M
Q
T
V
G
E
G
I
K
H
N
C
P
N
A
F
V
I
C
I
T
N
P
L
D
I
M
V
N
M
L
Q
K
F
--
S
GV
P
D
N
K
I
V
G
M
-
A
G
V
L
D
S
A
R
F
R
T
F
L
A
D
E
L
------
N
V
S
---
V
-
Q
Q
V
Q
A
Y
V
M
G
G
H
---
G
------------
D
T
M
V
-
P
L
T
K
M
S
N
V
A
G
----------------------------------
V
S
L
E
------
Q
L
-
V
K
E
G
K
L
K
Q
-------
E
R
L
D
-
A
I
V
S
--
R
-----------------------------------
T
---
R
S
---
G
G
G
E
---
I
V
A
L
------------
L
K
-----
T
--------
G
-----
S
-------------
A
Y
------------
Y
A
P
A
A
A
G
I
Q
M
A
E
S
F
-----
L
K
D
K
K
M
I
L
P
------
C
A
A
K
V
K
A
G
M
--
Y
G
L
D
E
D
L
F
V
G
V
P
T
E
-----
I
S
A
N
G
V
R
P
I
E
-
V
E
-
I
S
D
K
E
R
E
-
Q
-
L
Q
V
------------------------------------------------------
76
HHSearch
40.33
19%
-138
- C2 -
4BGV
4
MDH_PICTO
A:
[1-303]
-------
A
R
S
K
I
S
V
I
G
A
G
A
V
G
A
T
--
V
A
Q
---
T
--
L
--
A
-
I
-
R
Q
-
T
--
G
-
D
I
Y
I
F
D
I
V
D
G
L
--
A
E
G
K
A
--
L
D
I
L
---
E
G
A
PH
W
--
G
Y
D
L
D
----
I
K
G
F
C
T
A
D
E
S
K
--
Y
A
E
M
K
G
S
D
V
I
V
V
T
A
G
L
--------
A
-------
R
K
P
G
M
S
R
D
D
-------
L
L
-----------------------
L
K
N
I
G
---
I
M
K
S
V
G
E
A
I
K
K
Y
S
P
E
S
K
I
V
V
V
T
N
P
A
D
I
M
A
Y
A
I
Y
K
A
SG
I
--
S
P
E
R
I
I
G
L
-
G
G
S
L
D
S
T
R
F
R
T
F
L
A
Q
E
L
------
N
V
S
---
F
-
E
D
V
N
A
F
V
I
G
G
H
---
G
------------
D
D
M
V
-
P
F
I
R
Y
S
N
V
S
G
----------------------------------
I
P
I
E
------------
D
L
L
P
R
-------
E
K
I
D
-
E
I
V
---------
K
R
----------------------------
T
---
R
F
---
G
G
G
E
---
I
V
N
L
-
Y
K
----------------
T
--------
G
-----
S
-------------
A
F
------------
Y
A
P
G
I
S
I
A
V
M
V
E
S
I
-----
V
N
D
R
K
R
V
I
P
------
C
A
A
Y
I
T
G
E
H
S
K
T
Y
L
V
N
N
L
F
I
G
V
P
I
K
-----
I
G
K
N
G
V
E
K
I
Y
D
L
K
-
F
N
E
D
E
L
E
-
A
-
W
K
K
------------------------------------------------------
77
HHSearch
39.89
20%
-140
- C2 -
4ND2
4
?
A:
[1-301]
-----
M
I
E
R
R
K
I
A
V
I
G
S
G
Q
I
G
G
N
--
I
A
Y
---
I
--
V
--
G
-
K
-
D
N
L
---
A
-
D
V
V
L
F
D
I
A
E
G
I
--
P
Q
G
K
A
--
L
D
I
T
---
H
S
M
VM
F
--
G
S
T
S
K
----
V
I
----
G
T
N
D
Y
---
A
D
I
S
G
S
D
V
V
I
I
T
A
S
I
--------
P
-------
G
R
P
K
D
D
R
S
E
-------
L
L
-----------------------
F
G
N
A
R
---
I
L
D
S
V
A
E
G
V
K
K
Y
C
P
N
A
F
V
I
C
I
T
N
P
L
D
V
M
V
S
H
F
Q
K
V
S
G
L
--
P
H
N
K
V
C
G
M
-
A
G
V
L
D
S
S
R
F
R
T
F
I
A
Q
H
F
------
G
V
N
---
A
-
S
D
V
S
A
N
V
I
G
G
H
---
G
D
G
------------
M
V
-
P
A
T
S
S
V
S
V
G
G
V
----------------------------------
P
L
S
S
-----
F
I
-
K
Q
-
G
L
I
T
Q
-------
E
Q
I
D
-
E
I
V
---------
C
H
----------------------------
T
---
R
I
---
A
W
K
E
---
V
A
D
N
------------
L
K
-----
T
--------
G
-----
T
-------------
A
Y
------------
F
A
P
A
A
A
A
V
K
M
A
E
A
Y
-----
L
K
D
K
K
A
V
V
P
------
C
S
A
F
C
S
N
-
H
--
Y
G
V
K
-
G
I
Y
M
G
V
P
T
I
-----
I
G
K
N
G
V
E
D
I
L
E
L
D
-
L
T
P
L
E
Q
K
-
L
-
L
G
E
------------------------------------------------------
82
HHSearch
39.50
16%
-161
- C2 -
4PLZ
2
LDH_PLAFD
A:
[4-304]
--------
K
A
K
I
V
L
V
G
S
G
M
I
G
G
V
--
M
A
T
---
L
--
I
--
V
-
Q
-
K
N
L
---
G
-
D
V
V
L
F
D
I
V
K
N
M
--
P
H
G
K
A
L
-
D
T
S
H
---
T
N
V
M-
A
--
Y
S
N
C
K
----
V
-----
S
G
S
N
T
--
Y
D
D
L
A
G
A
D
V
V
I
V
T
A
G
F
-----------------------------
R
D
D
L
L
-----------------------
P
L
N
N
K
---
I
M
I
E
I
G
G
H
I
K
K
N
C
P
N
A
F
I
I
V
V
T
N
P
V
D
V
M
V
Q
L
L
H
Q
H
S
G
V
--
P
K
N
K
I
I
G
L
G
G
V
L
-
D
T
S
R
L
K
Y
Y
I
S
Q
K
L
------
N
V
C
---
P
-
R
D
V
N
A
H
I
V
G
A
H
GNK
M
V
L
L
K
R
Y
I
T
V
-
G
G
I
P
L
Q
-
E
F
I
N
N
K
L
-------------------------------------------------------
I
S
D
-------
A
E
L
E
-
A
I
---------
F
D
R
----------------------------
T
---
V
N
---
T
A
L
E
---
I
V
N
L
-------------------
H
--------
A
-----
S
-------------
P
Y
------------
V
A
P
A
A
A
I
I
E
M
A
E
S
Y
-----
L
K
D
L
K
K
V
L
I
------
C
S
T
L
L
E
G
Q
Y
---
G
-
H
S
D
I
F
G
G
T
P
V
V
-----
L
G
A
N
G
V
E
Q
V
I
E
L
Q
-
L
N
S
E
E
K
A
-
K
-
F
D
E
------------------------------------------------------
71
HHSearch
39.37
21%
-137
- C2 -
4ROR
2
MDH_METEP
A:
[2-320]
-------
A
R
S
K
I
A
L
I
G
A
G
Q
I
G
G
T
--
L
A
H
---
L
--
A
--
G
-
L
-
K
E
L
---
G
-
D
V
V
L
F
D
I
V
D
G
V
--
P
Q
G
K
A
--
L
D
I
A
---
E
S
A
PV
D
--
G
F
D
A
K
----
Y
S
----
G
A
S
D
Y
---
S
A
I
A
G
A
D
V
V
I
V
T
A
G
V
--------
P
-------
R
K
P
G
M
S
R
D
D
-------
L
I
-----------------------
G
I
N
L
K
---
V
M
E
A
V
G
A
G
I
K
E
H
A
P
D
A
F
V
I
C
I
T
N
P
L
D
A
M
V
W
A
L
Q
K
F
S
G
L
--
P
T
N
K
V
V
G
M
-
A
G
V
L
D
S
A
R
F
R
H
F
L
A
E
E
F
------
G
V
S
---
V
-
E
D
V
T
A
F
V
L
G
G
H
---
G
D
------------
D
M
V
-
P
L
T
R
Y
S
T
V
A
G
----------------------------------
V
P
L
------------------------
T
D
L
V
K
-
L
G
W
T
T
Q
E
K
---
L
D
A
M
-------------------
V
E
-----
R
T
---
R
K
---
G
G
G
E
---
I
V
N
L
------------
L
K
-----
T
--------
G
-----
S
-------------
A
F
------------
Y
A
P
A
A
S
A
I
A
M
A
E
S
Y
-----
L
R
D
K
K
R
V
L
P
------
C
A
A
Y
L
D
G
Q
Y
---
G
-
I
D
G
L
Y
V
G
V
P
V
V
-----
I
G
E
N
G
V
E
R
V
L
E
V
T
-
F
N
D
D
E
K
A
-
M
-
F
E
K
-
S
V
N
S
--
V
K
G
L
I
E
A
C
K
S
V
N
D
K
L
A
-------------------------------
80
HHSearch
39.05
17%
-135
- C2 -
3VKU
2
LDH_LACCA
A:
[7-312]
------
K
D
H
Q
K
V
I
L
V
G
D
G
A
V
G
S
S
--
Y
A
Y
---
A
--
M
--
V
-
L
-
Q
G
I
A
--
Q
-
E
I
G
I
V
D
I
F
K
D
K
--
T
K
G
D
A
--
I
D
L
E
---
D
A
L
P-
F
--
T
S
P
K
K
----
I
Y
------
S
A
E
--
Y
S
D
A
K
D
A
D
L
V
V
I
T
A
G
A
--------
P
--------------------------------------------------------
I
L
K
S
I
V
D
P
I
V
D
S
G
F
N
G
I
F
L
V
A
A
N
P
V
D
I
L
T
Y
A
T
W
K
L
S
G
F
--
P
K
N
R
V
V
G
S
G
T
S
L
-
D
T
A
R
F
R
Q
S
I
A
K
M
V
------
N
V
D
---
A
-
R
S
V
H
A
Y
I
M
G
-
E
---
H
G
-----------
D
T
E
F
-
P
V
W
S
H
A
N
I
G
G
----------------------------------
V
T
I
-
A
E
----
W
V
-
K
A
H
P
E
I
K
E
-------
D
K
L
V
-
K
M
F
E
---------
D
----------------------------
V
---
R
N
---
K
A
Y
E
---
I
I
K
L
-
K
--------------------------
G
-----
A
-------------
T
F
------------
Y
G
I
A
T
A
L
A
R
I
S
K
A
I
-----
L
N
D
E
N
A
V
L
P
------
L
S
V
Y
M
D
G
Q
Y
---
G
L
N
-
D
I
Y
I
G
T
P
A
V
-----
I
N
R
N
G
I
Q
N
I
L
E
I
P
-
L
T
D
H
E
E
E
-
S
-
M
Q
K
S
A
S
Q
L
--
K
K
V
--------------------------------------------