@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu07980: (2016-06-12 )
MKWMCSICCAAVLLAGGAAQAEAVPNEPINWGFKRSVNHQPPDAGKQLNSLIEKYDAFYLGNTKEKTIYLTFDNGYENGYTPKVLDVLKKHRVTGTFFVTGHFVKDQPQLIKRMSDEGHIIGNHSFHHPDLTTKTADQIQDELDSVNEEVYKITGKQDNLYLRPPRGVFSEYVLKETKRLGYQTVFWSVAFVDWKINNQKGKKYAYDHMIKQAHPGAIYLLHTVSRDNAEALDDAITDLKKQGYTFKSIDDLMFEKEMRLPSL
Atome Classification :
(20 SA)
---------------------------------------------------------------------------------------------------------.........10........20........30........40....-----------------....50........---60........70.......------------------------.80........90..-.-.....100.-----..--------.-.-..110.-......120.......130.---------------------------......140.......150.....---..160.......170--------------------------------------........180....----------------------...190-.------.......----------200--.........----210--------------------..--.-....---..220...---.----------.---.-.----230.......-.240-.......250-.......260.-----
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------------------------------MK
W
M
C
S
I
C
C
A
A
V
L
LAGGAAQAEAVPNEPINWGFKRSVNHQPPD
A
G
-----------------
K
Q
L
N
S
L
I
E
K
Y
D
A
FY---LGNTK
E
K
T
I
Y
L
T
FDNGYEN------------------------GY
T
P
K
V
L
D
V
L
K
KHRV-
T
-
G
T
F
F
V
T
GHF-----VK--------D-
Q
-
P
Q
L
I
K
R
-MSDEG
H
I
IGNHSFHHPDLTT---------------------------
K
T
A
D
Q
I
Q
D
E
L
D
S
V
N
E
E
V
Y
K
ITGKQ---D
N
L
Y
L
RP
P
R
G
V
F
S
E
---------------------------------------
Y
V
L
K
E
T
K
RLGY
Q
T
V
F
----------------------
W
S
V
A
F
--
V
------
D
W
K
INNQ----------K----GK
K
Y
A
Y
D
H
M
----
I
----------------------KQ--A-HP
G
A
---
I
Y
L
L
H
TVS---R----------D---
N
-
A
----
E
-
A
L
D
D
A
I
T
D
-
L
K
KQ-GYTF
K
S
I
D
D
L
-
M
F
E
K
EMRLPSL-----
1
PsiBlast_PDB
85.64
100%
-80
- C5 -
1W17
-
PDAA_BACSU
A:
[24-259]
--------------------------------------------------------------------------------------------------------------------------------
V
P
N
E
P
I
N
W
G
F
K
R
S
V
N
H
Q
P
P
D
A
G
-----------------
K
Q
L
N
S
L
I
E
K
Y
D
A
F
Y
---
L
G
N
T
K
E
K
T
I
Y
L
T
F
D
N
G
Y
E
N
------------------------
G
Y
T
P
K
V
L
D
V
L
K
K
H
R
V
-
T
-
G
T
F
F
V
T
G
H
F
-----
V
K
--------
D
-
Q
-
P
Q
L
I
K
R
-
M
S
D
E
G
H
I
I
G
N
H
S
F
H
H
P
D
L
T
T
---------------------------
K
T
A
D
Q
I
Q
D
E
L
D
S
V
N
E
E
V
Y
K
I
T
G
K
Q
---
D
N
L
Y
L
R
P
P
R
G
V
F
S
E
---------------------------------------
Y
V
L
K
E
T
K
R
L
G
Y
Q
T
V
F
----------------------
W
S
V
A
F
--
V
------
D
W
K
I
N
N
Q
----------
K
----
G
K
K
Y
A
Y
D
H
M
----
I
----------------------
K
Q
--
A
-
H
P
G
A
---
I
Y
L
L
H
T
V
S
---
R
----------
D
---
N
-
A
----
E
-
A
L
D
D
A
I
T
D
-
L
K
K
Q
-
G
Y
T
F
K
S
I
D
D
L
-
M
F
E
K
E
M
R
---------
2
PsiBlast_PDB
85.29
98%
-77
- C5 -
1NY1
-
PDAA_BACSU
A:
[24-258]
--------------------------------------------------------------------------------------------------------------------------------
V
P
N
E
P
I
N
W
G
F
K
R
S
V
N
H
Q
P
P
D
A
G
-----------------
K
Q
L
N
S
L
I
E
K
Y
D
A
F
Y
---
L
G
N
T
K
E
K
T
I
Y
L
T
F
D
N
G
Y
E
N
------------------------
G
Y
T
P
K
V
L
D
V
L
K
K
H
R
V
-
T
-
G
T
F
F
V
T
G
H
F
-----
V
K
--------
D
-
Q
-
P
Q
L
I
K
R
-
M
S
D
E
G
H
I
I
G
N
H
S
F
H
H
P
D
L
T
T
---------------------------
K
T
A
D
Q
I
Q
D
E
L
D
S
V
N
E
E
V
Y
K
I
T
G
K
Q
---
D
N
L
Y
L
R
P
P
R
G
V
F
S
E
---------------------------------------
Y
V
L
K
E
T
K
R
L
G
Y
Q
T
V
F
----------------------
W
S
V
A
F
--
V
------
D
W
K
I
N
N
Q
----------
K
----
G
K
K
Y
A
Y
D
H
M
----
I
----------------------
K
Q
--
A
-
H
P
G
A
---
I
Y
L
L
H
T
V
S
---
R
----------
D
---
N
-
A
----
E
-
A
L
D
D
A
I
T
D
-
L
K
K
Q
-
G
Y
T
F
K
S
I
D
D
L
-
M
F
E
K
E
M
----------
68
Fugue
82.24
97%
-71
- C5 -
1NY1
-
PDAA_BACSU
A:
[24-257]
--------------------------------------------------------------------------------------------------------------------------------
V
P
N
E
P
I
N
W
G
F
K
R
S
V
N
H
Q
P
P
D
A
G
-----------------
K
Q
L
N
S
L
I
E
K
Y
D
A
F
Y
---
L
G
N
T
K
E
K
T
I
Y
L
T
F
D
N
G
Y
E
N
------------------------
G
Y
T
P
K
V
L
D
V
L
K
K
H
R
V
-
T
-
G
T
F
F
V
T
G
H
F
-----
V
K
--------
D
-
Q
-
P
Q
L
I
K
R
M
S
-
D
E
G
H
I
I
G
N
H
S
F
H
H
P
D
L
T
T
---------------------------
K
T
A
D
Q
I
Q
D
E
L
D
S
V
N
E
E
V
Y
K
I
T
G
K
Q
---
D
N
L
Y
L
R
P
P
R
G
V
F
S
E
---------------------------------------
Y
V
L
K
E
T
K
R
L
G
Y
Q
T
V
F
----------------------
W
S
V
A
F
--
V
------
D
W
K
I
N
N
Q
----------
K
----
G
K
K
Y
A
Y
D
-
H
M
---
I
----------------------
K
Q
--
A
-
H
P
G
A
---
I
Y
L
L
H
T
V
S
---
R
----------
D
---
N
-
A
----
E
-
A
L
D
D
A
I
T
D
-
L
K
K
Q
-
G
Y
T
F
K
S
I
D
D
L
M
F
E
K
E
------------
47
HHSearch
78.16
100%
-81
- C5 -
1NY1
-
PDAA_BACSU
A:
[55-258]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
D
A
F
Y
---
L
G
N
T
K
E
K
T
I
Y
L
T
F
D
N
G
Y
E
N
------------------------
G
Y
T
P
K
V
L
D
V
L
K
K
H
R
V
-
T
-
G
T
F
F
V
T
G
H
F
-----
V
K
--------
D
-
Q
-
P
Q
L
I
K
R
-
M
S
D
E
G
H
I
I
G
N
H
S
F
H
H
P
D
L
T
T
---------------------------
K
T
A
D
Q
I
Q
D
E
L
D
S
V
N
E
E
V
Y
K
I
T
G
K
Q
---
D
N
L
Y
L
R
P
P
R
G
V
F
S
E
---------------------------------------
Y
V
L
K
E
T
K
R
L
G
Y
Q
T
V
F
----------------------
W
S
V
A
F
--
V
------
D
W
K
I
N
N
Q
----------
K
----
G
K
K
Y
A
Y
D
H
M
----
I
----------------------
K
Q
--
A
-
H
P
G
A
---
I
Y
L
L
H
T
V
S
---
R
----------
D
---
N
-
A
----
E
-
A
L
D
D
A
I
T
D
-
L
K
K
Q
-
G
Y
T
F
K
S
I
D
D
L
-
M
F
E
K
E
M
----------
3
PsiBlast_PDB
70.68
56%
-118
- C5 -
2J13
7
?
A:
[12-242]
-------------------------------------------------------------------------------------------------------------------------------
A
Y
T
N
T
P
H
N
W
G
I
----------
A
G
-----------------
K
L
Y
T
D
L
L
Q
K
N
G
G
F
Y
---
L
G
D
T
K
K
K
D
I
Y
L
T
F
D
N
G
Y
E
N
------------------------
G
Y
T
G
K
I
L
D
V
L
K
E
K
K
V
-
P
-
A
T
F
F
V
T
G
H
Y
-----
I
K
--------
T
-
Q
-
K
D
L
L
L
R
-
M
K
D
E
G
H
I
I
G
N
H
S
W
S
H
P
D
F
T
A
---------------------------
V
N
D
E
K
L
R
E
E
L
T
S
V
T
E
E
I
K
K
V
T
G
Q
K
---
E
V
K
Y
V
R
P
P
R
G
V
F
S
E
---------------------------------------
R
T
L
A
L
T
K
E
M
G
Y
Y
N
V
F
----------------------
W
S
L
A
F
--
L
------
D
W
------------------------------------------------------------
I
-
H
P
G
S
---
I
L
L
L
H
A
I
S
---
K
----------
D
---
N
-
A
----
E
-
A
L
A
K
I
I
D
D
-
L
R
E
K
-
G
Y
H
F
K
S
L
D
D
L
-
V
---------------
46
HHSearch
69.47
56%
-114
- C5 -
2J13
7
?
A:
[15-245]
----------------------------------------------------------------------------------------------------------------------------------
N
T
P
H
N
W
G
I
----------
A
G
-----------------
K
L
Y
T
D
L
L
Q
K
N
G
G
F
Y
---
L
G
D
T
K
K
K
D
I
Y
L
T
F
D
N
G
Y
E
N
------------------------
G
Y
T
G
K
I
L
D
V
L
K
E
K
K
V
-
P
-
A
T
F
F
V
T
G
H
Y
-----
I
K
--------
T
-
Q
-
K
D
L
L
L
R
-
M
K
D
E
G
H
I
I
G
N
H
S
W
S
H
P
D
F
T
A
---------------------------
V
N
D
E
K
L
R
E
E
L
T
S
V
T
E
E
I
K
K
V
T
G
Q
K
---
E
V
K
Y
V
R
P
P
R
G
V
F
S
E
---------------------------------------
R
T
L
A
L
T
K
E
M
G
Y
Y
N
V
F
----------------------
W
S
L
A
F
--
L
------
D
W
------------------------------------------------------------
I
-
H
P
G
S
---
I
L
L
L
H
A
I
S
---
K
----------
D
---
N
-
A
----
E
-
A
L
A
K
I
I
D
D
-
L
R
E
K
-
G
Y
H
F
K
S
L
D
D
L
-
V
K
S
N
------------
9
PsiBlast_PDB
59.31
29%
-99
- C5 -
4M1B
-
?
A:
[48-243]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
I
Y
---
K
G
D
T
S
K
K
Q
V
A
F
T
F
D
I
S
W
G
D
------------------------
K
K
A
I
P
I
L
D
T
L
K
E
R
D
I
K
N
-
A
T
F
F
L
S
A
A
W
-----
A
E
--------
R
-
H
-
P
D
V
V
E
R
-
I
I
K
D
G
H
E
I
G
S
M
G
Y
N
Y
T
S
Y
T
S
---------------------------
L
E
T
N
E
I
R
R
D
L
L
R
A
Q
D
V
F
T
K
L
G
V
K
Q
---
I
K
L
-
L
R
P
P
S
G
D
F
N
K
---------------------------------------
A
T
L
K
I
A
E
S
L
G
Y
T
V
V
H
----------------------
W
S
N
N
S
--
N
------
D
W
K
---
N
----------
P
----
G
V
N
K
I
V
S
T
V
----
S
----------------------
N
N
--
L
-
K
G
G
D
---
I
V
L
L
H
--
A
---
S
----------
D
---
S
-
A
LQTN
K
-
A
L
P
L
L
L
Q
K
-
L
K
S
D
-
G
Y
E
Q
I
S
V
S
Q
L
-
I
---------------
56
HHSearch
59.23
32%
-104
- C5 -
2C71
1
?
A:
[5-196]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
V
A
L
T
F
D
D
G
P
D
N
------------------------
V
L
T
A
R
V
L
D
K
L
D
K
Y
N
V
-
K
-
A
T
F
M
V
V
G
Q
R
-----
V
N
--------
D
S
T
-
A
A
I
I
R
R
-
M
V
N
S
G
H
E
I
G
N
H
S
W
S
Y
S
G
M
A
N
---------------------------
M
S
P
D
Q
I
R
K
S
I
A
D
T
N
A
V
I
Q
K
Y
A
G
T
----
T
P
K
F
F
R
P
P
N
L
E
T
S
P
---------------------------------------
T
L
F
N
N
---
V
D
L
V
-
F
V
----------------------
G
G
L
T
A
--
N
------
D
W
I
P
S
T
----------------
T
A
E
Q
R
A
A
A
V
----
I
----------------------
N
G
--
V
-
R
D
G
T
---
I
I
L
L
H
D
V
Q
---
P
EPH-------
P
---
T
-
P
----
E
-
A
L
D
I
I
I
P
T
-
L
K
S
R
-
G
Y
E
F
V
T
L
T
E
L
-
F
T
L
K
G
V
P
I
--------
48
HHSearch
57.19
28%
-83
* C5 *
4M1B
-
?
A:
[50-246]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
---
K
G
D
T
S
K
K
Q
V
A
F
T
F
D
I
S
W
G
D
------------------------
K
K
A
I
P
I
L
D
T
L
K
E
R
D
I
-
K
N
A
T
F
F
L
S
A
A
W
-----
A
E
--------
R
-
H
-
P
D
V
V
E
R
-
I
I
K
D
G
H
E
I
G
S
M
G
Y
N
Y
T
S
Y
T
S
---------------------------
L
E
T
N
E
I
R
R
D
L
L
R
A
Q
D
V
F
T
K
L
G
V
K
----
Q
I
K
L
L
R
P
P
S
G
D
F
N
K
---------------------------------------
A
T
L
K
I
A
E
S
L
G
Y
T
V
V
H
----------------------
W
S
N
N
S
--
N
------
D
W
K
N
P
-----------------
G
V
N
K
I
V
S
T
V
----
S
----------------------
N
N
--
L
-
K
G
G
D
---
I
V
L
L
H
A
S
D
---
S
AL--------
Q
---
T
-
N
----
K
-
A
L
P
L
L
L
Q
K
-
L
K
S
D
-
G
Y
E
Q
I
S
V
S
Q
L
-
I
S
N
T
------------
54
HHSearch
57.11
31%
-90
- C5 -
2C1I
3
PGDA_STRR6
A:
[231-422]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
K
H
Q
K
V
V
A
L
T
F
N
D
G
P
N
P
------------------------
A
T
T
P
Q
V
L
E
T
L
A
K
Y
D
I
-
K
-
A
T
F
F
V
L
G
K
N
-----
V
S
--------
G
-
N
-
E
D
L
V
K
R
-
I
K
S
E
G
H
V
V
G
N
H
S
W
S
H
P
I
L
S
Q
---------------------------
L
S
L
D
E
A
K
K
Q
I
T
D
T
E
D
V
L
T
K
V
L
G
S
----
S
S
K
L
M
R
P
P
Y
G
A
I
T
D
---------------------------------------
D
I
R
N
---
S
L
D
L
S
F
I
M
----------------------
W
D
V
D
S
--
L
------
D
W
K
S
K
-----------------
N
E
A
S
I
L
T
E
I
----
Q
----------------------
H
Q
--
V
-
A
N
G
S
---
I
V
L
M
H
D
I
H
---
S
----------
P
---
T
-
V
----
N
-
A
L
P
R
V
I
E
Y
-
L
K
N
Q
-
G
Y
T
F
V
T
I
P
E
M
-
L
N
T
R
L
K
A
---------
4
PsiBlast_PDB
56.61
32%
-94
- C5 -
2C1G
4
PGDA_STRR6
A:
[214-416]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
S
S
Y
L
L
E
K
D
A
A
L
Y
Q
S
Y
F
D
K
K
H
Q
K
V
V
A
L
T
F
D
D
G
P
N
P
------------------------
A
T
T
P
Q
V
L
E
T
L
A
K
Y
D
I
-
K
-
A
T
F
F
V
L
G
K
N
-----
V
S
--------
G
-
N
-
E
D
L
V
K
R
-
I
K
S
E
G
H
V
V
G
N
H
S
W
S
H
P
I
L
S
Q
---------------------------
L
S
L
D
E
A
K
K
Q
I
T
D
T
E
D
V
L
T
K
V
L
G
S
S
---
S
K
L
-
M
R
P
P
Y
G
A
I
T
D
---------------------------------------
D
I
---
R
N
S
L
D
L
S
F
I
M
----------------------
W
D
V
D
S
--
L
------
D
W
K
S
K
N
E
----------
A
----
S
I
L
T
E
I
Q
H
-----------------------------
Q
--
V
-
A
N
G
S
---
I
V
L
M
H
D
I
H
---
S
----------
P
---
T
-
V
----
N
-
A
L
P
R
V
I
E
Y
-
L
K
N
Q
-
G
Y
T
F
V
T
I
P
E
M
-
L
---------------
53
HHSearch
56.33
28%
-100
- C5 -
2Y8U
6
?
A:
[27-226]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
Q
C
T
T
P
N
T
I
A
L
T
F
D
D
G
P
S
E
-------------------------
Y
T
P
Q
L
L
D
L
L
S
R
Y
S
A
-
R
-
A
T
F
F
V
L
G
D
A
-----
A
A
--------
Q
-
N
-
P
G
L
L
Q
R
-
M
R
D
E
G
H
Q
V
G
A
H
T
Y
D
H
V
S
L
P
S
---------------------------
L
G
Y
D
G
I
A
S
Q
M
T
R
L
E
E
V
I
R
P
A
L
G
V
----
A
P
A
Y
M
R
P
P
Y
L
E
T
N
E
---------------------------------------
L
V
L
Q
V
M
R
D
L
D
Y
R
V
I
S
----------------------
A
S
V
D
T
--
K
------
D
Y
E
N
Q
D
-----------------
A
D
A
I
I
N
T
S
F
Q
L
F
L
----------------------
D
Q
--
L
D
A
G
G
N
---
I
V
L
A
H
D
I
H
---
Y
----------
W
---
T
-
V
----
A
S
L
A
E
R
M
L
Q
E
-
V
N
A
R
-
G
L
I
A
T
T
V
G
D
C
-
L
G
D
G
E
I
----------
5
PsiBlast_PDB
56.10
32%
-92
- C5 -
2C1I
3
PGDA_STRR6
A:
[214-416]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
S
S
Y
L
L
E
K
D
A
A
L
Y
Q
S
Y
F
D
K
K
H
Q
K
V
V
A
L
T
F
N
D
G
P
N
P
------------------------
A
T
T
P
Q
V
L
E
T
L
A
K
Y
D
I
-
K
-
A
T
F
F
V
L
G
K
N
-----
V
S
--------
G
-
N
-
E
D
L
V
K
R
-
I
K
S
E
G
H
V
V
G
N
H
S
W
S
H
P
I
L
S
Q
---------------------------
L
S
L
D
E
A
K
K
Q
I
T
D
T
E
D
V
L
T
K
V
L
G
S
S
---
S
K
L
-
M
R
P
P
Y
G
A
I
T
D
---------------------------------------
D
I
---
R
N
S
L
D
L
S
F
I
M
----------------------
W
D
V
D
S
--
L
------
D
W
K
S
K
N
E
----------
A
----
S
I
L
T
E
I
Q
H
-----------------------------
Q
--
V
-
A
N
G
S
---
I
V
L
M
H
D
I
H
---
S
----------
P
---
T
-
V
----
N
-
A
L
P
R
V
I
E
Y
-
L
K
N
Q
-
G
Y
T
F
V
T
I
P
E
M
-
L
---------------
57
HHSearch
55.19
27%
-100
- C5 -
3WX7
5
?
A:
[2-310]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
G
T
I
Y
L
T
F
D
D
G
P
I
N
-------------------------
A
S
I
D
V
I
N
V
L
N
Q
E
E
V
-
K
-
A
T
F
Y
F
N
A
W
H
-----
L
D
GIGDENED
R
-
A
-
L
E
A
L
K
L
-
A
L
D
S
G
H
I
V
A
N
H
S
Y
D
H
M
V
H
N
C
VEEFGPN
S
A
A
E
C
N
A
T
GDHQINSYQD
P
A
Y
D
A
S
M
F
A
E
N
L
S
V
L
E
K
Y
L
P
N
I
T
S
Y
P
NYK
A
N
E
F
A
R
L
P
Y
T
N
G
W
R
VTKD
F
K
A
D
GLCATSDDLKPWEPG
Y
A
C
D
TANPS
N
S
V
K
A
A
I
A
V
Q
N
I
L
A
N
N
G
Y
Q
T
H
G
----------------------
W
D
V
D
W
AP
E
------
N
W
G
I
A
M
P
----------
A
NSLT
E
A
E
P
F
L
G
Y
V
D
S
A
-
L
NTCAPTTINPINSKAQEFPCGT
P
L
--
H
-
A
D
K
V
---
I
V
L
T
H
E
F
L
---
F
EDGKRGMGAT
Q
---
N
-
L
----
P
-
K
L
T
K
F
I
Q
L
-
A
K
Q
A
-
G
Y
V
F
D
T
M
D
N
Y
-
T
P
N
W
------------
59
HHSearch
54.88
21%
-96
- C5 -
3RXZ
2
?
A:
[18-283]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
---
W
P
D
G
K
T
C
A
V
A
F
T
F
D
V
D
A
E
S
P
L
L
T
T
DPAFADR
M
G
T
M
S
H
Q
A
Y
G
P
L
V
G
V
P
R
L
L
G
I
L
D
E
F
N
V
-
P
-
G
T
F
F
V
P
G
Y
T
-----
A
H
--------
R
-
H
-
P
E
P
I
R
S
-
I
A
R
A
G
H
E
I
A
H
H
G
Y
L
H
E
S
L
V
G
---------------------------
A
D
E
D
T
E
R
K
I
L
T
R
G
I
E
A
L
E
E
V
A
G
V
----
H
P
V
G
Y
R
A
P
M
W
E
M
N
W
---------------------------------------
H
T
P
K
L
L
A
E
F
G
F
L
Y
D
S
TLMDSD
H
P
Y
E
L
AVGD
G
S
L
V
E
LP
V
S
W
A
L
--
D
------
D
W
Q
Q
Y
C
F
V
P
DFSGTG
L
I
E
----
T
P
A
K
A
I
E
L
W
R
A
E
-
L
----------------------
N
A
M
-
R
-
D
I
G
G
A
W
-
V
L
T
N
H
P
F
L
SGR
P
----------
G
---
R
-
A
----
A
-
A
L
R
E
F
I
A
E
-
V
C
A
M
D
D
V
W
V
A
G
M
S
Q
I
-
A
E
H
V
R
A
Q
---------
6
PsiBlast_PDB
54.57
32%
-91
- C5 -
2C71
1
?
A:
[5-188]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
V
A
L
T
F
D
D
G
P
D
N
------------------------
V
L
T
A
R
V
L
D
K
L
D
K
Y
N
V
-
K
-
A
T
F
M
V
V
G
Q
R
-----
V
N
--------
D
-
S
T
A
A
I
I
R
R
-
M
V
N
S
G
H
E
I
G
N
H
S
W
S
Y
S
G
M
A
N
---------------------------
M
S
P
D
Q
I
R
K
S
I
A
D
T
N
A
V
I
Q
K
Y
A
G
T
T
---
P
K
-
F
F
R
P
P
N
-----------------------------------------------
L
E
T
S
P
T
L
F
N
N
V
------------------------
D
L
V
F
--
V
G
G
LTAN
D
W
I
P
S
T
T
----------
A
----
E
Q
R
A
A
--
A
V
----
I
----------------------
N
G
--
V
-
R
D
G
T
---
I
I
L
L
H
D
V
Q
---
P
----------
E
PHP
T
-
P
----
E
-
A
L
D
I
I
I
P
T
-
L
K
S
R
-
G
Y
E
F
V
T
L
T
E
L
-----------------
7
PsiBlast_PDB
54.09
32%
-90
- C5 -
2C79
1
?
A:
[5-188]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
V
A
L
T
F
D
D
G
P
D
N
------------------------
V
L
T
A
R
V
L
D
K
L
D
K
Y
N
V
-
K
-
A
T
F
M
V
V
G
Q
R
-----
V
N
--------
D
-
S
T
A
A
I
I
R
R
-
M
V
N
S
G
H
E
I
G
N
H
S
W
S
Y
S
G
M
A
N
---------------------------
M
S
P
D
Q
I
R
K
S
I
A
D
T
N
A
V
I
Q
K
Y
A
G
T
T
---
P
K
-
F
F
R
P
P
N
-----------------------------------------------
L
E
T
S
P
T
L
F
N
N
V
------------------------
D
L
V
F
--
V
G
G
LTAN
D
W
I
P
S
T
T
----------
A
----
E
Q
R
A
A
--
A
V
----
I
----------------------
N
G
--
V
-
R
D
G
T
---
I
I
L
L
H
D
V
Q
---
P
----------
E
PHP
T
-
P
----
E
-
A
L
D
I
I
I
P
T
-
L
K
S
R
-
G
Y
E
F
V
T
L
T
E
L
-----------------
69
Fugue
52.99
25%
-97
- C5 -
2C1I
4
PGDA_STRR6
A:
[14-431]
F
E
Q
K
I
E
S
L
K
K
E
K
D
D
Q
LSEG
N
Q
K
E
H
F
R
Q
GQ
A
E
V
I
A
Y
Y
P
L
QGEKVI
S
S
V
R
E
L
I
N
Q
D
V
K
DKLESKD
N
L
V
F
Y
Y
T
E
Q
E
E
SGLKG
V
V
N
R
N
V
T
K
Q
I
Y
DI
E
E
T
E
K
T
SL
G
K
V
H
L
T
E
D
G
Q
P
F
T
L
D
Q
L
F
S
D
A
S
K
A
K
E
Q
L
I
K
E
L
T
S
F
D
L
S
A
W
N
F
D
Y
K
D
S
Q
I
I
L
YE
I
A
L
P
VSAFFDVIQS
S
Y
L
L
E
K
D
A
A
L
Y
Q
S
Y
---
F
D
K
K
H
Q
K
V
V
A
L
T
F
N
D
G
P
N
P
------------------------
A
T
T
P
Q
V
L
E
T
L
A
K
Y
D
I
-
K
-
A
T
F
F
V
L
G
K
N
-----
V
S
--------
G
-
N
-
E
D
L
V
K
R
-
I
K
S
E
G
H
V
V
G
N
H
S
W
S
H
P
I
L
S
Q
---------------------------
L
S
L
D
E
A
K
K
Q
I
T
D
T
E
D
V
L
T
K
V
L
G
S
S
---
S
K
L
M
-
R
P
P
Y
G
A
I
T
D
---------------------------------------
D
I
R
N
---
S
L
D
L
S
F
I
M
----------------------
W
D
V
D
S
--
L
------
D
W
K
S
K
N
-----------------
E
A
S
I
L
T
E
I
----
Q
----------------------
H
Q
--
V
-
A
N
G
S
---
I
V
L
M
H
D
I
H
---
S
----------
P
---
T
-
V
----
N
-
A
L
P
R
V
I
E
Y
-
L
K
N
Q
-
G
Y
T
F
V
T
I
P
E
M
-
L
N
T
R
L
K
A
H
E
L
Y
YSRDE
10
PsiBlast_PDB
50.64
28%
-67
- C5 -
2IW0
6
?
A:
[39-238]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
Q
P
G
L
V
A
L
T
Y
D
D
G
-
P
F
------------------------
T
F
T
P
Q
L
L
D
I
L
K
Q
N
D
V
-
R
-
A
T
F
F
V
N
G
N
N
WANIE
A
G
--------
S
-
N
-
P
D
T
I
R
R
-
M
R
A
D
G
H
L
V
G
S
H
T
Y
A
H
P
D
L
N
T
L--------------------------
S
S
A
D
R
I
S
-
Q
M
R
Q
L
E
E
A
T
R
R
I
D
G
F
A
---
P
K
-
Y
M
R
A
P
Y
L
S
C
D
A
---------------------------------------
G
C
Q
G
D
L
G
G
L
G
Y
H
I
I
D
----------------------
T
N
L
D
T
--
K
------
D
Y
E
N
N
K
P
----------
E
----
T
T
H
L
S
A
E
K
F
----
N
----------------------
N
E
LS
A
-
D
V
G
A
N
S
Y
I
V
L
S
H
D
V
H
---
E
----------
Q
---
T
-
V
----
V
-
S
L
T
Q
K
L
I
D
T
L
K
S
K
-
G
Y
R
A
V
T
V
G
E
C
-
L
---------------
51
HHSearch
50.56
26%
-72
- C5 -
2IW0
6
?
A:
[38-244]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
T
Q
P
G
L
V
A
L
T
Y
D
D
G
P
F
T
-------------------------
F
T
P
Q
L
L
D
I
L
K
Q
N
D
V
-
R
-
A
T
F
F
V
N
G
N
N
-----
W
A
NIEAG---
S
-
N
-
P
D
T
I
R
R
-
M
R
A
D
G
H
L
V
G
S
H
T
Y
A
H
P
D
L
N
T
---------------------------
L
S
S
A
D
R
I
S
Q
M
R
Q
L
E
E
A
T
R
R
I
D
G
F
----
A
P
K
Y
M
R
A
P
Y
L
S
C
D
A
---------------------------------------
G
C
Q
G
D
L
G
G
L
G
Y
H
I
I
D
----------------------
T
N
L
D
T
--
K
------
D
Y
E
N
N
K
P
----------
E
T
T
H
L
S
A
E
K
F
N
N
E
L
----
S
----------------------
A
D
--
V
G
A
N
S
Y
---
I
V
L
S
H
D
V
H
---
E
----------
Q
---
T
V
V
----
S
-
L
T
Q
K
L
I
D
T
-
L
K
S
K
-
G
Y
R
A
V
T
V
G
E
C
-
L
G
D
A
P
E
N
---------