@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu07990: (2016-06-12 )
MKIAVIGLGNMGQPIARNVLQAGYELTVYNRTKQKTEDLVTEGAQAADTPRLAAKSADIVITMLADDDSVSTVTFGEDGLLEGLAENGIHISMSTISVEFSEKLAAAHAEKGQFFLAAPVLGRPDAAAKAALRIITAGPAEAKQAAKPLLDSLSQQIFDVGEESKTANAAKISINFLLVSMLEALSESFLMMEKYGLEQKQFLEIASALFGSPVYQNYGTIMAEQKFEPAGFKMSLGLKDTNLALAAAKRVSANLPLAELAKSHFESGIEKGFGDLDWAALIKCIK
Atome Classification :
(21 SA)
----.........10........20........30........40........50........60........70...-.....80........90........100.......110.......120.......130.......140.......150.....-----..160.......170.......180........190.......200..-...-.-.210----.......220------.----.......230.......240.......250.......260.......270.......280....---
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----
M
K
I
A
V
I
GLGNMG
Q
P
I
A
R
N
V
L
QAG
Y
E
L
T
V
YNRTK
Q
K
T
E
D
L
V
TEGAQAADTPRLAAKSA
D
I
V
I
T
M
LADDDS
V
S
T
V
T
-FG
E
D
G
L
L
E
G
L
A
EN
G
I
H
I
S
M
S
T
I
S
V
E
F
S
E
K
L
A
A
A
HAEKG
Q
F
F
L
AAPVLGRP
D
A
A
A
K
A
A
L
R
I
I
TAG
P
A
E
A
K
Q
A
A
K
P
L
L
D
S
L
S
Q
Q
I
-----
F
DVGEESKTA
N
A
A
K
I
S
I
N
F
L
L
V
S
M
-
L
E
A
L
S
E
S
F
L
M
M
E
K
YGL
E
Q
K
Q
F
L
E
-
I
A
S
-
A
-
L
FG
S
----
P
V
Y
Q
N
Y
G
T
I
-------
M
----
A
EQKFEPAG
F
K
M
S
LGLKDT
N
L
A
L
A
A
A
K
R
VSANL
P
L
A
E
L
A
K
S
H
F
E
S
G
I
E
KGFGDL
D
W
A
A
L
I
K
CIK---
74
HHSearch
88.97
40%
-128
- C1 -
4GBJ
-
?
A:
[6-290]
----
E
K
I
A
F
L
G
L
G
N
L
G
T
P
I
A
E
I
L
L
E
A
G
Y
E
L
V
V
W
-------
E
P
L
T
K
L
G
A
T
V
V
E
N
A
I
D
A
I
T
P
G
G
I
V
F
S
V
L
A
D
D
A
A
V
E
E
L
F
S
M
E
---
L
V
E
K
L
G
K
D
G
V
H
V
S
M
S
T
I
S
P
E
T
S
R
Q
L
A
Q
V
H
E
W
Y
G
A
H
Y
V
G
A
P
I
F
A
R
P
E
A
V
R
A
K
V
G
N
I
C
L
S
G
N
A
G
A
K
E
R
I
K
P
I
V
E
N
F
V
K
G
V
-----
F
D
F
G
D
D
P
G
A
A
N
V
I
K
L
A
G
N
F
M
I
A
C
S
-
L
E
M
M
G
E
A
F
T
M
A
E
K
N
G
I
S
R
Q
S
I
Y
E
-
M
L
T
S
T
-
L
F
A
A
----
P
I
F
Q
N
Y
G
K
L
-------
V
----
A
S
N
T
Y
E
P
V
A
F
R
F
P
L
G
L
K
D
I
N
L
T
L
Q
T
A
S
D
V
N
A
P
M
P
F
A
D
I
I
R
N
R
F
I
S
G
L
A
K
G
R
E
N
L
D
W
G
A
L
A
L
G
A
S
---
1
PsiBlast_PDB
87.96
40%
-131
- C1 -
4GBJ
-
?
A:
[7-285]
-----
K
I
A
F
L
G
L
G
N
L
G
T
P
I
A
E
I
L
L
E
A
G
Y
E
L
V
V
W
-------
E
P
L
T
K
L
G
A
T
V
V
E
N
A
I
D
A
I
T
P
G
G
I
V
F
S
V
L
A
D
D
A
A
V
E
E
L
F
-
S
M
E
--
L
V
E
K
L
G
K
D
G
V
H
V
S
M
S
T
I
S
P
E
T
S
R
Q
L
A
Q
V
H
E
W
Y
G
A
H
Y
V
G
A
P
I
F
A
R
P
E
A
V
R
A
K
V
G
N
I
C
L
S
G
N
A
G
A
K
E
R
I
K
P
I
V
E
N
F
V
K
G
V
-----
F
D
F
G
D
D
P
G
A
A
N
V
I
K
L
A
G
N
F
M
I
A
C
S
-
L
E
M
M
G
E
A
F
T
M
A
E
K
N
G
I
S
R
Q
S
I
Y
E
M
L
T
S
-
T
-
L
F
A
A
----
P
I
F
Q
N
Y
G
K
L
-------
V
----
A
S
N
T
Y
E
P
V
A
F
R
F
P
L
G
L
K
D
I
N
L
T
L
Q
T
A
S
D
V
N
A
P
M
P
F
A
D
I
I
R
N
R
F
I
S
G
L
A
K
G
R
E
N
L
D
W
G
A
L
--------
83
HHSearch
82.23
31%
-126
- C1 -
3WS7
3
?
A:
[21-302]
----
M
R
V
G
F
I
G
L
G
I
M
G
G
P
M
A
T
H
L
L
K
A
G
F
L
A
A
V
Y
N
R
T
R
E
K
T
K
P
F
A
E
A
G
V
Y
V
A
E
S
P
A
D
L
A
K
R
V
D
V
V
I
V
M
V
S
D
A
P
D
V
E
Q
V
L
-
F
G
P
S
G
V
V
E
G
A
R
P
G
L
I
V
V
D
M
S
T
N
S
P
D
W
A
R
K
F
A
E
R
L
A
Q
Y
G
I
E
F
L
D
A
P
V
T
G
G
Q
K
G
A
I
E
G
T
L
T
I
M
V
G
G
K
E
E
L
F
H
R
L
L
P
I
F
K
A
M
G
R
D
I
-----
V
Y
M
G
P
-
V
G
Y
G
Q
A
M
K
L
V
N
Q
V
V
V
A
L
N
-
T
V
A
M
V
E
G
L
K
L
A
K
A
L
G
L
D
M
D
K
V
A
E
-
V
L
T
----
A
R
S
----
G
A
I
E
L
Y
L
P
K
-------
L
----
L
K
G
D
L
S
P
-
G
F
K
A
E
H
L
K
K
D
L
G
Y
V
L
E
E
A
R
K
R
G
V
K
L
P
G
A
E
L
A
Y
E
L
Y
R
K
M
V
E
D
G
A
G
S
L
G
I
H
A
L
G
F
------
6
PsiBlast_PDB
82.14
31%
-130
- C1 -
3W6Z
1
?
A:
[21-300]
----
M
R
V
G
F
I
G
L
G
I
M
G
G
P
M
A
T
H
L
L
K
A
G
F
L
A
A
V
Y
N
R
T
R
E
K
T
K
P
F
A
E
A
G
V
Y
V
A
E
S
P
A
D
L
A
K
R
V
D
V
V
I
V
M
V
S
D
A
P
D
V
E
Q
V
L
-
F
G
P
S
G
V
V
E
G
A
R
P
G
L
I
V
V
D
M
S
T
N
S
P
D
W
A
R
K
F
A
E
R
L
A
Q
Y
G
I
E
F
L
D
A
P
V
T
G
G
Q
K
G
A
I
E
G
T
L
T
I
M
V
G
G
K
E
E
L
F
H
R
L
L
P
I
F
K
A
M
G
R
D
I
-----
V
Y
M
G
P
V
G
Y
--
G
Q
A
M
M
L
V
N
Q
V
V
V
A
L
N
T
V
A
M
V
E
G
L
K
L
A
K
A
L
G
L
D
M
D
K
V
A
E
-
V
L
T
R
G
-
A
A
R
S
----
G
A
I
E
L
Y
L
P
K
-------
L
----
L
K
G
D
L
S
P
-
G
F
K
A
E
H
L
K
K
D
L
G
Y
V
L
E
E
A
R
K
R
G
V
K
L
P
G
A
E
L
A
Y
E
L
Y
R
K
M
V
E
D
G
A
G
S
L
G
I
H
A
L
--------
70
HHSearch
81.15
33%
-125
- C1 -
3OBB
5
SERDH_PSEAE
A:
[4-295]
----
K
Q
I
A
F
I
G
L
G
H
M
G
A
P
M
A
T
N
L
L
K
A
G
Y
L
L
N
V
F
D
L
V
Q
S
A
V
D
G
L
V
A
A
G
A
S
A
A
R
S
A
R
D
A
V
Q
G
A
D
V
V
I
S
M
L
P
A
S
Q
H
V
E
G
L
Y
-
L
D
D
D
G
L
L
A
H
I
A
P
-
T
L
V
L
E
C
S
T
I
A
P
T
S
A
R
K
I
H
A
A
A
R
E
R
G
L
A
M
L
D
A
P
V
S
G
G
T
A
G
A
A
A
G
T
L
T
F
M
V
G
G
D
A
E
A
L
E
K
A
R
P
L
F
E
A
M
G
R
N
I
-----
F
H
A
G
P
-
D
G
A
G
Q
V
A
K
V
C
N
N
Q
L
L
A
V
L
-
M
I
G
T
A
E
A
M
A
L
G
V
A
N
G
L
E
A
K
V
L
A
E
-
I
M
R
R
S
-
S
G
G
N
----
W
A
L
E
V
Y
N
P
W
PGVMENA
P
----
A
S
R
D
Y
S
G
-
G
F
M
A
Q
L
M
A
K
D
L
G
L
A
Q
E
A
A
Q
A
S
A
S
S
T
P
M
G
S
L
A
L
S
L
Y
R
L
L
L
K
Q
G
Y
A
E
R
D
F
S
V
V
Q
K
L
F
D
---
66
HHSearch
81.06
31%
-108
- C1 -
3PDU
3
?
A:
[2-286]
----
T
T
Y
G
F
L
G
L
G
I
M
G
G
P
M
A
A
N
L
V
R
A
G
F
D
V
T
V
W
N
R
N
P
A
K
C
A
P
L
V
A
L
G
A
R
Q
A
S
S
P
A
E
V
C
A
A
C
D
I
T
I
A
M
L
A
D
P
A
A
A
R
E
V
C
-
F
G
A
N
G
V
L
E
G
I
G
G
G
R
G
Y
I
D
M
S
T
V
D
D
E
T
S
T
A
I
G
A
A
V
T
A
R
G
G
R
F
L
E
A
P
V
S
G
T
K
K
P
A
E
D
G
T
L
I
I
L
A
A
G
D
Q
S
L
F
T
D
A
G
P
A
F
A
A
L
G
K
K
C
-----
L
H
L
G
E
-
V
G
Q
G
A
R
M
K
L
V
V
N
M
I
M
G
Q
M
-
M
T
A
L
G
E
G
M
A
L
G
R
N
C
G
L
D
G
G
Q
L
L
E
-
V
L
D
A
G
-
A
M
A
N
----
P
M
F
K
G
K
G
Q
M
-------
L
----
L
S
G
E
F
P
T
-
S
F
P
L
K
H
M
Q
K
D
L
R
L
A
V
E
L
G
D
R
L
G
Q
P
L
H
G
A
A
T
A
N
E
S
F
K
R
A
R
A
A
G
H
A
D
E
D
F
A
A
V
F
R
V
L
E
---
3
PsiBlast_PDB
80.48
32%
-106
- C1 -
3PEF
6
?
A:
[3-283]
-----
K
F
G
F
I
G
L
G
I
M
G
S
A
M
A
K
N
L
V
K
A
G
C
S
V
T
I
W
N
R
S
P
E
K
A
E
E
L
A
A
L
G
A
E
R
A
A
T
P
C
E
V
V
E
S
C
P
V
T
F
A
M
L
A
D
P
A
A
A
E
E
V
C
-
F
G
K
H
G
V
L
E
G
I
G
E
G
R
G
Y
V
D
M
S
T
V
D
P
A
T
S
Q
R
I
G
V
A
V
V
A
K
G
G
R
F
L
E
A
P
V
S
G
S
K
K
P
A
E
D
G
T
L
I
I
L
A
A
G
D
R
N
L
Y
D
E
A
M
P
G
F
E
K
M
G
K
K
I
-----
I
H
L
G
D
V
G
K
G
A
E
-
M
K
L
V
V
N
M
V
M
G
G
M
-
M
A
C
F
C
E
G
L
A
L
G
E
K
A
G
L
A
T
D
A
I
L
D
V
I
G
A
-
G
-
A
M
A
N
----
P
M
F
A
L
K
G
G
L
-------
I
----
R
D
R
N
F
A
P
A
-
F
P
L
K
H
M
Q
K
D
L
R
L
A
V
A
L
G
D
R
V
G
Q
P
L
V
A
S
A
A
A
N
E
L
F
K
G
A
R
A
A
G
F
G
D
E
D
F
S
A
I
F
K
------
5
PsiBlast_PDB
80.24
31%
-127
- C1 -
3WS7
3
?
A:
[21-300]
----
M
R
V
G
F
I
G
L
G
I
M
G
G
P
M
A
T
H
L
L
K
A
G
F
L
A
A
V
Y
N
R
T
R
E
K
T
K
P
F
A
E
A
G
V
Y
V
A
E
S
P
A
D
L
A
K
R
V
D
V
V
I
V
M
V
S
D
A
P
D
V
E
Q
V
L
-
F
G
P
S
G
V
V
E
G
A
R
P
G
L
I
V
V
D
M
S
T
N
S
P
D
W
A
R
K
F
A
E
R
L
A
Q
Y
G
I
E
F
L
D
A
P
V
T
G
G
Q
K
G
A
I
E
G
T
L
T
I
M
V
G
G
K
E
E
L
F
H
R
L
L
P
I
F
K
A
M
G
R
D
I
V
Y
M
G
P
V
G
Y
G
Q
A
M
K
L
V
N
Q
V
V
V
A
L
N
--
T
V
A
M
-
V
E
G
L
K
----
L
A
K
A
L
G
L
D
M
D
K
V
A
E
-
V
L
T
----
A
R
S
----
G
A
I
E
L
Y
L
P
K
-------
L
----
L
K
G
D
L
S
P
-
G
F
K
A
E
H
L
K
K
D
L
G
Y
V
L
E
E
A
R
K
R
G
V
K
L
P
G
A
E
L
A
Y
E
L
Y
R
K
M
V
E
D
G
A
G
S
L
G
I
H
A
L
--------
71
HHSearch
79.84
29%
-109
- C1 -
1VPD
2
?
A:
[6-289]
----
M
K
V
G
F
I
G
L
G
I
M
G
K
P
M
S
K
N
L
L
K
A
G
Y
S
L
V
V
S
D
R
N
P
E
A
I
A
D
V
I
A
A
G
A
E
T
A
S
T
A
K
A
I
A
E
Q
C
D
V
I
I
T
M
L
P
N
S
P
H
V
K
E
V
A
-
L
G
E
N
G
I
I
E
G
A
K
P
G
T
V
L
I
D
M
S
S
I
A
P
L
A
S
R
E
I
S
D
A
L
K
A
K
G
V
E
M
L
D
A
P
V
S
G
G
E
P
K
A
I
D
G
T
L
S
V
M
V
G
G
D
K
A
I
F
D
K
Y
Y
D
L
M
K
A
M
A
G
S
V
-----
V
H
T
G
D
-
I
G
A
G
N
V
T
K
L
A
N
Q
V
I
V
A
L
N
-
I
A
A
M
S
E
A
L
T
L
A
T
K
A
G
V
N
P
D
L
V
Y
Q
-
A
I
R
G
G
-
L
A
G
S
----
T
V
L
D
A
K
A
P
M
-------
V
----
M
D
R
N
F
K
P
-
G
F
R
I
D
L
H
I
K
D
L
A
N
A
L
D
T
S
H
G
V
G
A
Q
L
P
L
T
A
A
V
M
E
M
M
Q
A
L
R
A
D
G
H
G
N
D
D
H
S
A
L
A
C
Y
Y
----
2
PsiBlast_PDB
79.69
32%
-98
- C1 -
3DOJ
1
GLYR1_ARATH
A:
[22-306]
----
M
E
V
G
F
L
G
L
G
I
M
G
K
A
M
S
M
N
L
L
K
N
G
F
K
V
T
V
W
N
R
T
L
S
K
C
D
E
L
V
E
H
G
A
S
V
C
E
S
P
A
E
V
I
K
K
C
K
Y
T
I
A
M
L
S
D
P
C
A
A
L
S
V
V
-
F
D
K
G
G
V
L
E
Q
I
C
E
G
K
G
Y
I
D
M
S
T
V
D
A
E
T
S
L
K
I
N
E
A
I
T
G
K
G
G
R
F
V
E
G
P
V
S
G
S
K
K
P
A
E
D
G
Q
L
I
I
L
A
A
G
D
K
A
L
F
E
E
S
I
P
A
F
D
V
L
G
K
R
S
-----
F
Y
L
G
Q
V
G
N
G
A
K
-
M
K
L
I
V
N
M
I
M
G
S
M
-
M
N
A
F
S
E
G
L
V
L
A
D
K
S
G
L
S
S
D
T
L
L
D
-
I
L
D
L
G
-
A
M
T
N
----
P
M
F
K
G
K
G
P
S
-------
M
----
N
K
S
S
Y
P
P
A
-
F
P
L
K
H
Q
Q
K
D
M
R
L
A
L
A
L
G
D
E
N
A
V
S
M
P
V
A
A
A
A
N
E
A
F
K
K
A
R
S
L
G
L
G
D
L
D
F
S
A
V
I
E
A
V
K
---
67
HHSearch
79.65
31%
-105
- C1 -
3PEF
6
?
A:
[2-286]
----
Q
K
F
G
F
I
G
L
G
I
M
G
S
A
M
A
K
N
L
V
K
A
G
C
S
V
T
I
W
N
R
S
P
E
K
A
E
E
L
A
A
L
G
A
E
R
A
A
T
P
C
E
V
V
E
S
C
P
V
T
F
A
M
L
A
D
P
A
A
A
E
E
V
C
-
F
G
K
H
G
V
L
E
G
I
G
E
G
R
G
Y
V
D
M
S
T
V
D
P
A
T
S
Q
R
I
G
V
A
V
V
A
K
G
G
R
F
L
E
A
P
V
S
G
S
K
K
P
A
E
D
G
T
L
I
I
L
A
A
G
D
R
N
L
Y
D
E
A
M
P
G
F
E
K
M
G
K
K
I
-----
I
H
L
G
D
-
V
G
K
G
A
E
M
K
L
V
V
N
M
V
M
G
G
M
-
M
A
C
F
C
E
G
L
A
L
G
E
K
A
G
L
A
T
D
A
I
L
D
-
V
I
G
A
G
-
A
M
A
N
----
P
M
F
A
L
K
G
G
L
-------
I
----
R
D
R
N
F
A
P
-
A
F
P
L
K
H
M
Q
K
D
L
R
L
A
V
A
L
G
D
R
V
G
Q
P
L
V
A
S
A
A
A
N
E
L
F
K
G
A
R
A
A
G
F
G
D
E
D
F
S
A
I
F
K
T
Y
E
---
21
PsiBlast_CBE
79.35
32%
-100
- C1 -
3PDU
3
?
H:
[7-286]
---------
L
G
L
G
I
M
G
G
P
M
A
A
N
L
V
R
A
G
F
D
V
T
V
W
N
R
N
P
A
K
C
A
P
L
V
A
L
G
A
R
Q
A
S
S
P
A
E
V
C
A
A
C
D
I
T
I
A
M
L
A
D
P
A
A
A
R
E
V
C
-
F
G
A
N
G
V
L
E
G
I
G
G
G
R
G
Y
I
D
M
S
T
V
D
D
E
T
S
T
A
I
G
A
A
V
T
A
R
G
G
R
F
L
E
A
P
V
S
G
T
K
K
P
A
E
D
G
T
L
I
I
L
A
A
G
D
Q
S
L
F
T
D
A
G
P
A
F
A
A
L
G
K
K
C
-----
L
H
L
G
E
V
G
Q
G
A
R
-
M
K
L
V
V
N
M
I
M
G
Q
M
-
M
T
A
L
G
E
G
M
A
L
G
R
N
C
G
L
D
G
G
Q
L
L
E
-
V
L
D
-
A
G
A
M
A
N
----
P
M
F
K
G
K
G
Q
M
-------
L
----
L
S
G
E
F
-
P
T
S
F
P
L
K
H
M
Q
K
D
L
R
L
A
V
E
L
G
D
R
L
G
Q
P
L
H
G
A
A
T
A
N
E
S
F
K
R
A
R
A
A
G
H
A
D
E
D
F
A
A
V
F
R
V
L
E
---
23
PsiBlast_CBE
79.12
32%
-101
- C1 -
3PDU
4
?
F:
[7-286]
---------
L
G
L
G
I
M
G
G
P
M
A
A
N
L
V
R
A
G
F
D
V
T
V
W
N
R
N
P
A
K
C
A
P
L
V
A
L
G
A
R
Q
A
S
S
P
A
E
V
C
A
A
C
D
I
T
I
A
M
L
A
D
P
A
A
A
R
E
V
C
-
F
G
A
N
G
V
L
E
G
I
G
G
G
R
G
Y
I
D
M
S
T
V
D
D
E
T
S
T
A
I
G
A
A
V
T
A
R
G
G
R
F
L
E
A
P
V
S
G
T
K
K
P
A
E
D
G
T
L
I
I
L
A
A
G
D
Q
S
L
F
T
D
A
G
P
A
F
A
A
L
G
K
K
C
-----
L
H
L
G
E
V
G
Q
G
A
R
-
M
K
L
V
V
N
M
I
M
G
Q
M
-
M
T
A
L
G
E
G
M
A
L
G
R
N
C
G
L
D
G
G
Q
L
L
E
-
V
L
D
-
A
G
A
M
A
N
----
P
M
F
K
G
K
G
Q
M
-------
L
----
L
S
G
E
F
-
P
T
S
F
P
L
K
H
M
Q
K
D
L
R
L
A
V
E
L
G
D
R
L
G
Q
P
L
H
G
A
A
T
A
N
E
S
F
K
R
A
R
A
A
G
H
A
D
E
D
F
A
A
V
F
R
V
L
E
---
86
Fugue
78.93
31%
-98
* C1 *
3DOJ
1
GLYR1_ARATH
A:
[18-309]
GSHM
M
E
V
G
F
L
G
L
G
I
M
G
K
A
M
S
M
N
L
L
K
N
G
F
K
V
T
V
W
N
R
T
L
S
K
C
D
E
L
V
E
H
G
A
S
V
C
E
S
P
A
E
V
I
K
K
C
K
Y
T
I
A
M
L
S
D
P
C
A
A
L
S
V
V
-
F
D
K
G
G
V
L
E
Q
I
C
E
G
K
G
Y
I
D
M
S
T
V
D
A
E
T
S
L
K
I
N
E
A
I
T
G
K
G
G
R
F
V
E
G
P
V
S
G
S
K
K
P
A
E
D
G
Q
L
I
I
L
A
A
G
D
K
A
L
F
E
E
S
I
P
A
F
D
V
L
G
K
R
S
-----
F
Y
L
G
Q
V
G
-
N
G
A
K
M
K
L
I
V
N
M
I
M
G
S
M
-
M
N
A
F
S
E
G
L
V
L
A
D
K
S
G
L
S
S
D
T
L
L
D
-
I
L
D
-
L
G
A
M
T
N
----
P
M
F
K
G
K
G
P
S
-------
M
----
N
K
S
S
Y
P
P
-
A
F
P
L
K
H
Q
Q
K
D
M
R
L
A
L
A
L
G
D
E
N
A
V
S
M
P
V
A
A
A
A
N
E
A
F
K
K
A
R
S
L
G
L
G
D
L
D
F
S
A
V
I
E
A
V
K
FSR
26
PsiBlast_CBE
78.93
32%
-101
- C1 -
3PDU
3
?
C:
[7-286]
---------
L
G
L
G
I
M
G
G
P
M
A
A
N
L
V
R
A
G
F
D
V
T
V
W
N
R
N
P
A
K
C
A
P
L
V
A
L
G
A
R
Q
A
S
S
P
A
E
V
C
A
A
C
D
I
T
I
A
M
L
A
D
P
A
A
A
R
E
V
C
-
F
G
A
N
G
V
L
E
G
I
G
G
G
R
G
Y
I
D
M
S
T
V
D
D
E
T
S
T
A
I
G
A
A
V
T
A
R
G
G
R
F
L
E
A
P
V
S
G
T
K
K
P
A
E
D
G
T
L
I
I
L
A
A
G
D
Q
S
L
F
T
D
A
G
P
A
F
A
A
L
G
K
K
C
-----
L
H
L
G
E
V
G
Q
G
A
R
-
M
K
L
V
V
N
M
I
M
G
Q
M
-
M
T
A
L
G
E
G
M
A
L
G
R
N
C
G
L
D
G
G
Q
L
L
E
-
V
L
D
-
A
G
A
M
A
N
----
P
M
F
K
G
K
G
Q
M
-------
L
----
L
S
G
E
F
-
P
T
S
F
P
L
K
H
M
Q
K
D
L
R
L
A
V
E
L
G
D
R
L
G
Q
P
L
H
G
A
A
T
A
N
E
S
F
K
R
A
R
A
A
G
H
A
D
E
D
F
A
A
V
F
R
V
L
E
---
22
PsiBlast_CBE
78.89
32%
-100
- C1 -
3PDU
2
?
G:
[7-286]
---------
L
G
L
G
I
M
G
G
P
M
A
A
N
L
V
R
A
G
F
D
V
T
V
W
N
R
N
P
A
K
C
A
P
L
V
A
L
G
A
R
Q
A
S
S
P
A
E
V
C
A
A
C
D
I
T
I
A
M
L
A
D
P
A
A
A
R
E
V
C
-
F
G
A
N
G
V
L
E
G
I
G
G
G
R
G
Y
I
D
M
S
T
V
D
D
E
T
S
T
A
I
G
A
A
V
T
A
R
G
G
R
F
L
E
A
P
V
S
G
T
K
K
P
A
E
D
G
T
L
I
I
L
A
A
G
D
Q
S
L
F
T
D
A
G
P
A
F
A
A
L
G
K
K
C
-----
L
H
L
G
E
V
G
Q
G
A
R
-
M
K
L
V
V
N
M
I
M
G
Q
M
-
M
T
A
L
G
E
G
M
A
L
G
R
N
C
G
L
D
G
G
Q
L
L
E
-
V
L
D
-
A
G
A
M
A
N
----
P
M
F
K
G
K
G
Q
M
-------
L
----
L
S
G
E
F
-
P
T
S
F
P
L
K
H
M
Q
K
D
L
R
L
A
V
E
L
G
D
R
L
G
Q
P
L
H
G
A
A
T
A
N
E
S
F
K
R
A
R
A
A
G
H
A
D
E
D
F
A
A
V
F
R
V
L
E
---
85
HHSearch
78.86
30%
-101
- C1 -
4DLL
1
?
A:
[32-313]
----
R
K
I
T
F
L
G
T
G
S
M
G
L
P
M
A
R
R
L
C
E
A
G
Y
A
L
Q
V
W
N
R
T
P
A
R
A
A
S
L
A
A
L
G
A
T
I
H
E
Q
A
R
A
A
A
R
D
A
D
I
V
V
S
M
L
E
N
G
A
V
V
Q
D
V
L
-
F
A
-
Q
G
V
A
A
A
M
K
P
G
S
L
F
L
D
M
A
S
I
T
P
R
E
A
R
D
H
A
A
R
L
G
A
L
G
I
A
H
L
D
T
P
V
S
G
G
T
V
G
A
E
Q
G
T
L
V
I
M
A
G
G
K
P
A
D
F
E
R
S
L
P
L
L
K
V
F
G
R
-
A
-----
T
H
V
G
P
-
H
G
S
G
Q
L
T
K
L
A
N
Q
M
I
V
G
I
T
-
I
G
A
V
A
E
A
L
L
F
A
T
K
G
G
A
D
M
A
K
V
K
E
-
A
I
T
G
G
-
F
A
D
S
----
R
V
L
Q
L
H
G
Q
R
-------
M
----
V
E
R
D
F
A
P
-
R
A
R
L
S
I
Q
L
K
D
M
R
N
A
L
A
T
A
Q
E
I
G
F
D
A
P
I
T
G
L
F
E
Q
L
Y
A
E
G
V
E
H
G
L
T
D
L
D
Q
S
G
L
F
V
E
L
----
25
PsiBlast_CBE
78.86
32%
-99
- C1 -
3PDU
4
?
D:
[7-286]
---------
L
G
L
G
I
M
G
G
P
M
A
A
N
L
V
R
A
G
F
D
V
T
V
W
N
R
N
P
A
K
C
A
P
L
V
A
L
G
A
R
Q
A
S
S
P
A
E
V
C
A
A
C
D
I
T
I
A
M
L
A
D
P
A
A
A
R
E
V
C
-
F
G
A
N
G
V
L
E
G
I
G
G
G
R
G
Y
I
D
M
S
T
V
D
D
E
T
S
T
A
I
G
A
A
V
T
A
R
G
G
R
F
L
E
A
P
V
S
G
T
K
K
P
A
E
D
G
T
L
I
I
L
A
A
G
D
Q
S
L
F
T
D
A
G
P
A
F
A
A
L
G
K
K
C
-----
L
H
L
G
E
V
G
Q
G
A
R
-
M
K
L
V
V
N
M
I
M
G
Q
M
-
M
T
A
L
G
E
G
M
A
L
G
R
N
C
G
L
D
G
G
Q
L
L
E
-
V
L
D
-
A
G
A
M
A
N
----
P
M
F
K
G
K
G
Q
M
-------
L
----
L
S
G
E
F
-
P
T
S
F
P
L
K
H
M
Q
K
D
L
R
L
A
V
E
L
G
D
R
L
G
Q
P
L
H
G
A
A
T
A
N
E
S
F
K
R
A
R
A
A
G
H
A
D
E
D
F
A
A
V
F
R
V
L
E
---
27
PsiBlast_CBE
78.78
32%
-100
- C1 -
3PDU
5
?
B:
[7-286]
---------
L
G
L
G
I
M
G
G
P
M
A
A
N
L
V
R
A
G
F
D
V
T
V
W
N
R
N
P
A
K
C
A
P
L
V
A
L
G
A
R
Q
A
S
S
P
A
E
V
C
A
A
C
D
I
T
I
A
M
L
A
D
P
A
A
A
R
E
V
C
-
F
G
A
N
G
V
L
E
G
I
G
G
G
R
G
Y
I
D
M
S
T
V
D
D
E
T
S
T
A
I
G
A
A
V
T
A
R
G
G
R
F
L
E
A
P
V
S
G
T
K
K
P
A
E
D
G
T
L
I
I
L
A
A
G
D
Q
S
L
F
T
D
A
G
P
A
F
A
A
L
G
K
K
C
-----
L
H
L
G
E
V
G
Q
G
A
R
-
M
K
L
V
V
N
M
I
M
G
Q
M
-
M
T
A
L
G
E
G
M
A
L
G
R
N
C
G
L
D
G
G
Q
L
L
E
-
V
L
D
-
A
G
A
M
A
N
----
P
M
F
K
G
K
G
Q
M
-------
L
----
L
S
G
E
F
-
P
T
S
F
P
L
K
H
M
Q
K
D
L
R
L
A
V
E
L
G
D
R
L
G
Q
P
L
H
G
A
A
T
A
N
E
S
F
K
R
A
R
A
A
G
H
A
D
E
D
F
A
A
V
F
R
V
L
E
---
4
PsiBlast_PDB
78.66
32%
-100
- C1 -
3PDU
3
?
A:
[7-286]
---------
L
G
L
G
I
M
G
G
P
M
A
A
N
L
V
R
A
G
F
D
V
T
V
W
N
R
N
P
A
K
C
A
P
L
V
A
L
G
A
R
Q
A
S
S
P
A
E
V
C
A
A
C
D
I
T
I
A
M
L
A
D
P
A
A
A
R
E
V
C
-
F
G
A
N
G
V
L
E
G
I
G
G
G
R
G
Y
I
D
M
S
T
V
D
D
E
T
S
T
A
I
G
A
A
V
T
A
R
G
G
R
F
L
E
A
P
V
S
G
T
K
K
P
A
E
D
G
T
L
I
I
L
A
A
G
D
Q
S
L
F
T
D
A
G
P
A
F
A
A
L
G
K
K
C
-----
L
H
L
G
E
V
G
Q
G
A
R
-
M
K
L
V
V
N
M
I
M
G
Q
M
-
M
T
A
L
G
E
G
M
A
L
G
R
N
C
G
L
D
G
G
Q
L
L
E
-
V
L
D
-
A
G
A
M
A
N
----
P
M
F
K
G
K
G
Q
M
-------
L
----
L
S
G
E
F
-
P
T
S
F
P
L
K
H
M
Q
K
D
L
R
L
A
V
E
L
G
D
R
L
G
Q
P
L
H
G
A
A
T
A
N
E
S
F
K
R
A
R
A
A
G
H
A
D
E
D
F
A
A
V
F
R
V
L
E
---
13
PsiBlast_PDB
77.39
32%
-116
- C1 -
3OBB
5
SERDH_PSEAE
A:
[5-292]
-----
Q
I
A
F
I
G
L
G
H
M
G
A
P
M
A
T
N
L
L
K
A
G
Y
L
L
N
V
F
D
L
V
Q
S
A
V
D
G
L
V
A
A
G
A
S
A
A
R
S
A
R
D
A
V
Q
G
A
D
V
V
I
S
M
L
P
A
S
Q
H
V
E
G
L
Y
-
L
D
D
D
G
L
L
A
H
I
A
P
-
T
L
V
L
E
C
S
T
I
A
P
T
S
A
R
K
I
H
A
A
A
R
E
R
G
L
A
M
L
D
A
P
V
S
G
G
T
A
G
A
A
A
G
T
L
T
F
M
V
G
G
D
A
E
A
L
E
K
A
R
P
L
F
E
A
M
G
R
N
I
-----
F
H
A
G
P
D
G
-
A
G
Q
V
A
K
V
C
N
N
Q
L
L
A
V
L
-
M
I
G
T
A
E
A
M
A
L
G
V
A
N
G
L
E
A
K
V
L
A
E
-
I
M
R
-
R
-
S
S
G
G
NWAL
E
V
Y
N
P
W
P
G
V
-------
M
ENAP
A
S
R
D
Y
S
-
G
G
F
M
A
Q
L
M
A
K
D
L
G
L
A
Q
E
A
A
Q
A
S
A
S
S
T
P
M
G
S
L
A
L
S
L
Y
R
L
L
L
K
Q
G
Y
A
E
R
D
F
S
V
V
Q
K
------