@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu09080: (2016-06-14 )
MKTVLELKNVTKNIRGRTIIDDLSFTIREGEVFGFLGPNGAGKTTTIRMMVGLMKLSKGDVLICGQSITKEYAKAIKHIGAIVENPELYKFLSGYKNLQQFARMVKGVTKEKIDEVVELVGLTDRIHDKVKTYSLGMRQRLGLAQCLLHDPKVLILDEPTNGLDPAGIREIRDHLKKLTRERGMAVIVSSHLLSEMELMCDRIAILQKGKLIDIQNVKDENIDENDTYFFQVEQPSEAATVLNQYDLLSKTNGVEIKLAKEEVPAVIELLVMQQIRIYEVKVITKSLEDRFLEMTGETKEEVQHA
Atome Classification :
(26 SA)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10....--.----...--20........30........40........50........60-.........----70----.....------...80...------.....90..-......---100...---....---110---...----.....120......---...-130.......140.......150.......160.......170.......180.......190.......200.......210.-------....-------..--220.....-.--.230.......240.......250....--...260.--......270.......280.......290---......-...300...----------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MK
T
V
L
E
L
K
N
V
T
K
N
IR--G----
R
T
I
--IDD
L
S
F
T
I
RE
G
E
V
F
G
F
LGPNGAGKT
T
T
I
R
M
M
V
G
L
M
KLSKG
D
--
V
L
I
C
G
Q
S
I
T
----
K
E
----
Y
A
K
A
I
------
K
H
I
G
A
IVE------
N
P
E
L
Y
K
F
L
S
-
G
Y
K
N
L
Q
---
Q
F
A
R
M
V
---
K
G
V
T
---
K
E
----
K
I
D
----
E
V
V
E
L
V--G
L
T
D
R
I
---
H
D
K
-
V
K
T
Y
S
L
G
M
R
Q
R
L
G
L
A
Q
C
L
LHDP
K
V
L
I
L
DEPTNGL
D
P
A
G
I
R
E
I
R
D
H
L
K
K
L
T
R
ER
G
M
A
V
I
V
S
S
H
L
L
S
E
M
E
L
M
C
D
R
I
A
I
LQKG
K
L
I
D
-------
I
QNV-------KD--ENIDEND
T
-
Y
--
F
F
Q
VEQPS
E
A
A
T
V
L
N
Q
Y
D
LLSKTN
G
V
E
I
--
K
L
A
K
E
E
V
--
P
A
V
I
E
L
L
V
M
Q
Q
I
R
I
Y
E
V
K
V
I
T
K
S
L
E
D
R
-----
F
L
E
MTG-E
T
K
E
E
VQHA----------------------------------------------
1
PsiBlast_PDB
87.05
37%
-136
- C1 -
1VPL
2
?
A:
[18-244]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
K
D
L
R
K
R
I
G
--
K
----
K
E
I
--
L
K
G
I
S
F
E
I
E
E
G
E
I
F
G
L
I
G
P
N
G
A
G
K
T
T
T
L
R
I
I
S
T
L
I
K
P
S
S
G
I
--
V
T
V
F
G
K
N
V
V
----
E
E
----
P
H
E
V
R
------
K
L
I
S
Y
L
P
E
------
E
A
G
A
Y
R
N
M
Q
-
G
I
E
Y
L
R
---
F
V
A
G
F
Y
---
A
S
S
S
S
E
I
E
E
----
M
V
E
----
R
A
T
E
I
A
--
G
L
G
E
K
I
---
K
D
R
-
V
S
T
Y
S
K
G
M
V
R
K
L
L
I
A
R
A
L
M
V
N
P
R
L
A
I
L
D
E
P
T
S
G
L
D
V
L
N
A
R
E
V
R
K
I
L
K
Q
A
S
Q
E
-
G
L
T
I
L
V
S
S
H
N
M
L
E
V
E
F
L
C
D
R
I
A
L
I
H
N
G
T
I
V
E
-------
T
G
T
V
E
E
L
K
E
R
Y
K
A
--
Q
N
I
E
E
--------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
81.50
28%
-116
- C1 -
4YER
4
?
A:
[5-310]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
I
V
V
E
N
L
V
K
K
F
G
--
D
----
F
E
A
--
V
K
G
V
S
F
S
V
K
K
G
E
I
F
A
F
L
G
P
N
G
A
G
K
T
T
T
I
H
M
L
T
T
L
L
K
P
T
S
G
K
--
A
W
V
A
G
H
D
V
L
----
K
E
----
P
R
E
V
R
------
R
K
I
G
I
V
F
Q
------
D
Q
S
L
D
R
E
L
T
-
A
Y
E
N
M
Y
---
I
H
G
K
I
Y
----
G
Y
G
---
G
E
----
K
L
K
----
K
R
I
L
E
L
--
L
E
F
V
E
L
LEF
K
D
K
P
V
K
T
F
S
G
G
M
A
R
R
L
E
I
A
R
S
L
I
H
E
P
E
V
L
F
L
D
E
P
T
I
G
L
D
P
H
T
R
A
H
M
W
E
Y
I
S
K
M
K
K
E
H
N
M
T
I
F
L
T
T
H
Y
M
D
E
A
E
Q
L
A
D
R
V
A
I
I
D
H
G
K
I
I
A
-------
L
G
T
P
-------
T
E
L
K
R
M
V
G
K
E
I
I
-
Y
V
R----------
D
F
I
E
S
C
R
K
L
P
D
G
R
L
E
L
N
V
--
E
D
--------------------
I
E
E
I
T
Y
H
K
P
T
L
N
D
V
-----
F
L
H
L
T
G
R
E
L
R
E
E
--------------------------------------------------
25
PsiBlast_CBE
76.89
31%
-143
- C1 -
3TUZ
1
METN_ECOLI
D:
[24-250]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
K
L
S
N
I
T
K
V
F
H
QG
T
----
R
T
I
QA
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
--
V
L
V
D
G
Q
E
L
T
TLSE
S
E
----
L
T
K
A
R
------
R
Q
I
G
M
I
F
Q
------
H
F
N
L
L
S
S
R
T
-
V
F
G
N
V
A
LPL
E
L
D
N
T
P
---
K
D
E
V
---
K
R
----
R
V
T
----
E
L
L
S
L
V
--
G
L
G
D
K
H
---
D
S
Y
-
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
-------
Q
D
T
V
-------
S
E
---------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
76.72
31%
-143
- C1 -
3TUI
1
METN_ECOLI
C:
[23-250]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
M
I
K
L
S
N
I
T
K
V
F
H
QG
T
----
R
T
I
QA
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
--
V
L
V
D
G
Q
E
L
T
TLSE
S
E
----
L
T
K
A
R
------
R
Q
I
G
M
I
F
Q
------
H
F
N
L
L
S
S
R
T
-
V
F
G
N
V
A
LPL
E
L
D
N
T
P
---
K
D
E
V
---
K
R
----
R
V
T
----
E
L
L
S
L
V
--
G
L
G
D
K
H
---
D
S
Y
-
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
-------
Q
D
T
V
-------
S
E
---------------------------------------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
76.14
31%
-143
- C1 -
3TUI
1
METN_ECOLI
D:
[24-250]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
K
L
S
N
I
T
K
V
F
H
QG
T
----
R
T
I
QA
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
--
V
L
V
D
G
Q
E
L
T
TLSE
S
E
----
L
T
K
A
R
------
R
Q
I
G
M
I
F
Q
------
H
F
N
L
L
S
S
R
T
-
V
F
G
N
V
A
LPL
E
L
D
N
T
P
---
K
D
E
V
---
K
R
----
R
V
T
----
E
L
L
S
L
V
--
G
L
G
D
K
H
---
D
S
Y
-
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
-------
Q
D
T
V
-------
S
E
---------------------------------------------------------------------------------------------------------------------------------------------------
58
Fugue
75.13
26%
-110
- C1 -
1OXS
23
?
C:
[1-352]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
R
I
I
V
K
N
V
S
K
V
F
K
--
K
GK--
V
V
A
--
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
--
L
Y
F
D
D
R
L
V
A
----
S
N
GKLI
V
P
P
E
D
------
R
K
I
G
M
V
F
Q
------
T
W
A
L
Y
P
N
L
T
-
A
F
E
N
I
A
---
F
P
L
T
N
M
KMS
K
E
E
I
---
R
K
----
R
V
E
----
E
V
A
K
I
L
--
D
I
H
H
V
L
---
N
H
F
-
P
R
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
-------
V
G
K
---------
P
--
E
D
L
Y
D
N
P
V
-
S
--
I
Q
V
A
S
L
I
G
E
----
I
N
E
L
E
G
K
V
T
N
E
G
V
V
I
--
G
S
L
R
F
P
V
--
S
V
S
S
D
-
R
A
I
I
G
I
R
P
E
D
V
K
L
S
K
D
V
I
K
D
D
-----
S
W
I
L
V
G
-
K
G
K
V
K
V
I
G
Y
QGGLFRITITPLDSEEEIFTYSDHPIHSGEEVLVYVRKDKIKVFEK
26
PsiBlast_CBE
74.63
31%
-152
- C1 -
3TUI
1
METN_ECOLI
H:
[23-250]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
M
I
K
L
S
N
I
T
K
V
F
H
QG
T
----
R
T
I
QA
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
--
V
L
V
D
G
Q
E
L
T
TLSE
S
E
----
L
T
K
A
R
------
R
Q
I
G
M
I
F
Q
------
H
F
N
L
L
S
S
R
T
-
V
F
G
N
V
A
LPL
E
L
D
N
T
P
---
K
D
E
V
---
K
R
----
R
V
T
----
E
L
L
S
L
V
--
G
L
G
D
K
H
---
D
S
Y
-
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
-------
Q
D
T
V
-------
S
E
---------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
74.44
31%
-148
- C1 -
3TUZ
1
METN_ECOLI
G:
[24-250]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
K
L
S
N
I
T
K
V
F
H
QG
T
----
R
T
I
QA
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
--
V
L
V
D
G
Q
E
L
T
TLSE
S
E
----
L
T
K
A
R
------
R
Q
I
G
M
I
F
Q
------
H
F
N
L
L
S
S
R
T
-
V
F
G
N
V
A
LPL
E
L
D
N
T
P
---
K
D
E
V
---
K
R
----
R
V
T
----
E
L
L
S
L
V
--
G
L
G
D
K
H
---
D
S
Y
-
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
-------
Q
D
T
V
-------
S
E
---------------------------------------------------------------------------------------------------------------------------------------------------
46
HHSearch
74.32
30%
-138
* C1 *
3TUI
1
METN_ECOLI
C:
[23-254]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
M
I
K
L
S
N
I
T
K
V
F
H
--
Q
GTRT
I
Q
A
--
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
--
V
L
V
D
G
Q
E
L
T
----
T
L
SESE
L
T
K
A
R
------
R
Q
I
G
M
I
F
Q
------
H
F
N
L
L
S
S
R
T
-
V
F
G
N
V
A
---
L
P
L
E
L
D
---
N
T
P
K
DEV
K
R
----
R
V
T
----
E
L
L
S
L
V
--
G
L
G
D
K
H
---
D
S
Y
-
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
-------
Q
D
T
V
-------
S
E
--
V
F
S
H
---------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
74.18
31%
-150
- C1 -
3TUZ
1
METN_ECOLI
H:
[23-250]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
M
I
K
L
S
N
I
T
K
V
F
H
QG
T
----
R
T
I
QA
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
--
V
L
V
D
G
Q
E
L
T
TLSE
S
E
----
L
T
K
A
R
------
R
Q
I
G
M
I
F
Q
------
H
F
N
L
L
S
S
R
T
-
V
F
G
N
V
A
LPL
E
L
D
N
T
P
---
K
D
E
V
---
K
R
----
R
V
T
----
E
L
L
S
L
V
--
G
L
G
D
K
H
---
D
S
Y
-
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
-------
Q
D
T
V
-------
S
E
---------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
74.14
31%
-150
- C1 -
3TUZ
1
METN_ECOLI
C:
[23-250]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
M
I
K
L
S
N
I
T
K
V
F
H
QG
T
----
R
T
I
QA
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
--
V
L
V
D
G
Q
E
L
T
TLSE
S
E
----
L
T
K
A
R
------
R
Q
I
G
M
I
F
Q
------
H
F
N
L
L
S
S
R
T
-
V
F
G
N
V
A
LPL
E
L
D
N
T
P
---
K
D
E
V
---
K
R
----
R
V
T
----
E
L
L
S
L
V
--
G
L
G
D
K
H
---
D
S
Y
-
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
-------
Q
D
T
V
-------
S
E
---------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
73.89
31%
-152
- C1 -
3DHW
-
METN_ECOLI
C:
[1-227]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
K
L
S
N
I
T
K
V
F
H
QG
T
----
R
T
I
QA
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
--
V
L
V
D
G
Q
E
L
T
TLSE
S
E
----
L
T
K
A
R
------
R
Q
I
G
M
I
F
Q
------
H
F
N
L
L
S
S
R
T
-
V
F
G
N
V
A
LPL
E
L
D
N
T
P
---
K
D
E
V
---
K
R
----
R
V
T
----
E
L
L
S
L
V
--
G
L
G
D
K
H
---
D
S
Y
-
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
E
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
-------
Q
D
T
V
-------
S
E
---------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
73.59
31%
-152
- C1 -
3TUJ
-
METN_ECOLI
C:
[0-227]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
M
I
K
L
S
N
I
T
K
V
F
H
QG
T
----
R
T
I
QA
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
--
V
L
V
D
G
Q
E
L
T
TLSE
S
E
----
L
T
K
A
R
------
R
Q
I
G
M
I
F
Q
------
H
F
N
L
L
S
S
R
T
-
V
F
G
N
V
A
LPL
E
L
D
N
T
P
---
K
D
E
V
---
K
R
----
R
V
T
----
E
L
L
S
L
V
--
G
L
G
D
K
H
---
D
S
Y
-
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
-------
Q
D
T
V
-------
S
E
---------------------------------------------------------------------------------------------------------------------------------------------------
59
Fugue
73.48
25%
-129
- C1 -
3TUZ
3
METN_ECOLI
H:
[23-362]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
M
I
K
L
S
N
I
T
K
V
F
H
--
Q
GTRT
I
Q
A
--
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
--
V
L
V
D
G
Q
E
L
T
TLSE
S
E
----
L
T
K
A
R
------
R
Q
I
G
M
I
F
Q
------
H
F
N
L
L
S
S
R
T
-
V
F
G
N
V
A
---
L
P
L
E
L
D
NTP
K
D
E
V
---
K
R
----
R
V
T
----
E
L
L
S
L
V
--
G
L
G
D
K
H
---
D
S
Y
-
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
QDTVSEV
F
S
H
P
-------
K
T
--
P
L
A
Q
K
F
I
Q
-
S
--
T
L
H
L
D
I
P
E
D
Y
Q
E
R
L
Q
A
E
P
F
T
D
C
V
P
M
L
R
L
--
E
F
T
G
Q
S
V
DA
P
L
L
S
E
T
A
R
R
F
N
V
N
N
N
I
I
S
A
Q
M
D
Y
A
G
G
V
KFGIM
L
T
E
M
H
G
-
T
Q
Q
D
T
Q
A
A
I
AWLQEHHVKVEV----------------------------------
27
PsiBlast_CBE
73.31
31%
-143
- C1 -
3TUI
1
METN_ECOLI
G:
[24-250]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
K
L
S
N
I
T
K
V
F
H
QG
T
----
R
T
I
QA
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
--
V
L
V
D
G
Q
E
L
T
TLSE
S
E
----
L
T
K
A
R
------
R
Q
I
G
M
I
F
Q
------
H
F
N
L
L
S
S
R
T
-
V
F
G
N
V
A
LPL
E
L
D
N
T
P
---
K
D
E
V
---
K
R
----
R
V
T
----
E
L
L
S
L
V
--
G
L
G
D
K
H
---
D
S
Y
-
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
-------
Q
D
T
V
-------
S
E
---------------------------------------------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
70.84
31%
-110
- C1 -
4P33
6
LPTB_ECOLI
B:
[1-215]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
T
L
T
A
K
N
L
A
K
A
Y
K
--
G
----
R
R
V
--
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
II
I
D
D
D
D
I
S
L
L
----
P
L
----
H
A
R
A
R
------
R
G
I
G
Y
L
P
Q
------
E
A
S
I
F
R
R
L
S
-
V
Y
D
N
L
M
---
A
V
L
Q
I
R
---
D
D
L
S
---
A
E
QRED
R
A
N
----
E
L
M
E
E
F
--
H
I
E
H
L
R
---
D
S
M
-
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
Q
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
-
R
D
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
HHSearch
70.69
28%
-124
- C1 -
3RLF
3
MALK_ECOLI
A:
[2-225]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
V
Q
L
Q
N
V
T
K
A
W
G
--
E
----
V
V
V
--
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
--
L
F
I
G
E
K
R
M
N
----
D
T
-----
P
P
A
E
------
R
G
V
G
M
V
F
Q
------
S
Y
A
L
Y
P
H
L
S
-
V
A
E
N
M
S
---
F
G
L
K
L
A
---
G
A
K
K
E
V
I
N
Q
----
R
V
N
----
Q
V
A
E
V
L
--
Q
L
A
H
L
L
---
D
R
K
-
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
-------
V
G
K
P
-------
L
E
--
L
Y
H
Y
P
--------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
70.24
31%
-112
- C1 -
4P33
7
LPTB_ECOLI
A:
[1-215]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
T
L
T
A
K
N
L
A
K
A
Y
K
--
G
----
R
R
V
--
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
D
D
I
S
L
L
----
P
L
----
H
A
R
A
R
------
R
G
I
G
Y
L
P
Q
------
E
A
S
I
F
R
R
L
S
-
V
Y
D
N
L
M
---
A
V
L
Q
I
R
---
D
D
L
S
---
A
E
Q
R
E
D
R
A
N
----
E
L
M
E
E
F
--
H
I
E
H
L
R
---
D
S
M
-
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
Q
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
-
R
D
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
69.64
31%
-118
- C1 -
4P32
2
LPTB_ECOLI
B:
[1-215]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
T
L
T
A
K
N
L
A
K
A
Y
K
--
G
----
R
R
V
--
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
II
I
D
D
D
D
I
S
L
L
----
P
L
----
H
A
R
A
R
------
R
G
I
G
Y
L
P
Q
------
E
A
S
I
F
R
R
L
S
-
V
Y
D
N
L
M
---
A
V
L
Q
I
R
---
D
D
L
S
---
A
E
QRED
R
A
N
----
E
L
M
E
E
F
--
H
I
E
H
L
R
---
D
S
M
-
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
-
R
D
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
63
Fugue
69.35
23%
-111
- C1 -
3B60
2
MSBA_SALTY
A:
[10-581]
W
Q
T
F
R
R
L
W
P
T
I
A
PFK
A
G
L
I
V
A
G
I
A
L
I
L
N
A
A
S
D
T
F
M
L
S
L
LKPLLDDGFGKTDRSVLLW
M
P
L
V
V
I
G
L
M
I
L
R
G
I
T
S
Y
I
S
S
Y
C
I
S
W
V
S
G
K
V
V
M
T
M
R
R
R
L
F
G
H
M
M
G
MPVAFFDKQS
T
G
T
L
L
S
R
I
T
Y
D
S
E
Q
V
A
S
S
S
S
G
A
L
I
T
V
V
R
E
G
A
S
I
I
G
L
F
I
M
M
FYYS
W
Q
L
S
I
I
L
V
V
L
A
P
I
V
S
I
A
I
R
V
V
S
K
R
F
R
S
I
S
K
N
M
Q
N
T
M
G
Q
V
T
T
S
A
E
Q
M
L
K
G
H
KEVLIFGG
Q
E
V
E
T
K
R
F
D
K
V
S
N
K
M
R
L
Q
G
M
K
M
V
S
A
S
S
I
S
D
P
I
I
Q
L
I
A
S
L
A
L
A
F
V
L
Y
A
A
S
FPSVMDSLT
A
G
T
I
T
V
V
F
S
S
M
I
A
L
M
R
P
L
K
S
L
T
N
V
N
A
Q
F
Q
R
G
M
A
A
C
Q
T
L
F
A
I
L
D
SEQEK
D
E
G
K
RVIDR
A
T
G
D
L
E
F
R
N
V
T
F
T
Y
P
--
G
RE--
V
P
A
--
L
R
N
I
N
L
K
I
P
A
G
K
T
V
A
L
V
G
R
S
G
S
G
K
S
T
I
A
S
L
I
T
R
F
Y
D
I
D
E
G
H
--
I
L
M
D
G
H
D
L
R
----
E
Y
----
T
L
A
S
L
------
R
N
Q
V
A
L
V
S
Q
N
V
H
L
F
N
D
T
V
A
N
N
I
A
Y
A
R
T
E
E
Y
---
S
R
E
Q
I
E
---
E
A
A
R
---
M
A
----
Y
A
M
----
D
F
I
N
K
M
DN
G
L
D
T
I
I
---
G
E
N
-
G
V
L
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
L
R
D
S
P
I
L
I
L
D
E
A
T
S
A
L
D
T
E
S
E
R
A
I
Q
A
A
L
D
E
L
Q
K
N
R
T
S
L
V
I
--
A
H
R
L
S
T
I
E
-
Q
A
D
E
I
V
V
V
E
D
G
I
I
V
E
-------
R
G
T
---------------------------------------------------------------------------------------
H
S
E
-----
L
L
A
Q
H
G
-
V
Y
A
Q
L
H
K
M
Q
FG--------------------------------------------
5
PsiBlast_PDB
68.37
31%
-115
- C1 -
4P32
2
LPTB_ECOLI
A:
[1-215]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
T
L
T
A
K
N
L
A
K
A
Y
K
--
G
----
R
R
V
--
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
D
D
I
S
L
L
----
P
L
----
H
A
R
A
R
------
R
G
I
G
Y
L
P
Q
------
E
A
S
I
F
R
R
L
S
-
V
Y
D
N
L
M
---
A
V
L
Q
I
R
---
D
D
L
S
---
A
E
Q
R
E
D
R
A
N
----
E
L
M
E
E
F
--
H
I
E
H
L
R
---
D
S
M
-
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
-
R
D
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
68.21
31%
-112
- C1 -
4P31
2
LPTB_ECOLI
A:
[1-215]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
T
L
T
A
K
N
L
A
K
A
Y
K
--
G
----
R
R
V
--
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
D
D
I
S
L
L
----
P
L
----
H
A
R
A
R
------
R
G
I
G
Y
L
P
Q
------
E
A
S
I
F
R
R
L
S
-
V
Y
D
N
L
M
---
A
V
L
Q
I
R
---
D
D
L
S
---
A
E
Q
R
E
D
R
A
N
----
E
L
M
E
E
F
--
H
I
E
H
L
R
---
D
S
M
-
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
-
R
D
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
67.72
31%
-109
- C1 -
4QC2
2
?
A:
[2-216]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
T
L
T
A
K
N
L
A
K
A
Y
K
--
G
----
R
R
V
--
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
D
D
I
S
L
L
----
P
L
----
H
A
R
A
R
------
R
G
I
G
Y
L
P
Q
------
E
A
S
I
F
R
R
L
S
-
V
Y
D
N
L
M
---
A
V
L
Q
I
R
---
D
D
L
S
---
A
E
Q
R
E
D
R
A
N
----
E
L
M
E
E
F
--
H
I
E
H
L
R
---
D
S
M
-
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
-
R
D
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
65.97
31%
-111
- C1 -
4QC2
2
?
B:
[2-216]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
T
L
T
A
K
N
L
A
K
A
Y
K
--
G
----
R
R
V
--
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
II
I
D
D
D
D
I
S
L
L
----
P
L
----
H
A
R
A
R
------
R
G
I
G
Y
L
P
Q
------
E
A
S
I
F
R
R
L
S
-
V
Y
D
N
L
M
---
A
V
L
Q
I
R
---
D
D
L
S
---
A
E
QRED
R
A
N
----
E
L
M
E
E
F
--
H
I
E
H
L
R
---
D
S
M
-
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
-
R
D
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
65.41
33%
-120
- C1 -
2D62
7
?
A:
[7-221]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
K
L
I
N
I
W
K
R
F
G
--
D
----
V
T
A
--
V
K
D
L
S
L
E
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
E
E
P
T
R
G
Q
--
I
Y
I
E
-
D
N
L
V
----
A
D
----
P
E
K
G
V
F
V
P
PKE
R
D
V
A
M
V
F
Q
------
S
Y
A
L
Y
P
H
M
T
-
V
Y
D
N
I
A
----
F
P
L
K
L
---
R
K
V
P
---
K
Q
----
E
I
D
K
R
V
R
E
V
A
E
M
L
--
G
L
T
E
L
L
---
N
R
K
-
P
R
E
L
S
G
G
Q
R
Q
R
V
A
L
G
R
A
I
I
R
R
P
K
V
F
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
K
M
R
A
E
L
K
K
L
Q
R
Q
L
G
V
T
T
I
Y
V
T
H
D
Q
V
E
A
M
T
M
G
D
R
I
A
V
M
N
K
G
E
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
50.00
30%
18
- C1 -
4YER
4
?
A:
[2-311]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
E
D
I
I
V
V
E
N
L
V
K
K
F
G
--
D
----
F
E
A
--
V
K
G
V
S
F
S
V
K
K
G
E
I
F
A
F
L
G
P
N
G
A
G
K
T
T
T
I
H
M
L
T
T
L
L
K
P
T
S
G
K
--
A
W
V
A
G
H
D
V
L
----
K
E
----
P
R
E
V
R
------
R
K
I
G
I
V
F
Q
------
D
Q
S
L
D
R
E
L
T
-
A
Y
E
N
M
Y
---
I
H
G
K
I
Y
---
G
Y
G
G
E
K
L
K
K
----
R
I
L
----
E
L
L
E
F
V
--
E
L
L
E
F
K
---
D
K
P
-
V
K
T
F
S
G
G
M
A
R
R
L
E
I
A
R
S
L
I
H
E
P
E
V
L
F
L
D
E
P
T
I
G
L
D
P
H
T
R
A
H
M
W
E
Y
I
S
K
M
K
K
E
H
N
M
T
I
F
L
T
T
H
Y
M
D
E
A
E
Q
L
A
D
R
V
A
I
I
D
H
G
K
I
I
A
-------
L
G
T
P
-------
T
E
--
L
K
R
M
V
G
K
E
I
I
--
Y
V
R
--------
D
F
I
E
-
S
C
R
K
L
P
D
G
R
L
E
L
N
V
E
D
--------------------
I
E
E
I
T
Y
H
K
P
T
L
N
D
V
-----
F
L
H
L
T
G
-
R
E
L
R
E
E
G
------------------------------------------------