@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu09400: (2016-06-14 )
MNAEEKKGLQRAIEEITEIAKGFGLDFYPMRYEICPAEIIYTFGAYGMPTRFSHWSFGKQFHKMKLHYDLGLSKIYELVINSDPCYAFLLDSNSLIQNKLIVAHVLAHCDFFKNNCRFQNTKRDMVESMAATAERIKHYEQVHGIKEVESFLDAILSIQEHIDPSLVRPKLQWSVDDEEEEIEEAATPYDDLWSLDEKKPKKQVKKSKKPFPPRPEKDILLFIEEHSRELEPWQRDILTMMREEMLYFWPQLETKIMNEGWASYWHQRIIRELDLTSDEAIEFAKLNAGVVQPSKTGINPYYLGLKIFEDIEKRYNNPTEEMKKMGVQPDSGREKMFEVREIESDISFIRNYLTKELVMREDLYLFQKQGRDYKIIDKQWKSVRDQLVSMRVNGGFPYLTVNDGDYMKNNELYIKHWYEGIELDLKYLEKVLPYLFQLWGRSVHIESVLEDKEVMFSYDGKGVHRRYL
Atome Classification :
(20 SA)
---------------------------------.........10........20........30---------.-...-....40.......-----------.50....-....60----------........70.......--..80.....-----------------...90...------.-....100-------.....-----------..110..----------.----....120---.......130--....------...140...--------...----.150...---.------...160..-.....170.---......180....-..----------.190.---......200.--......--210...-.----------...220.......-------230..--.....240.---......250...------------------------------------..------------.-.----------------------------------260.......270--------------------------.......-..-------280.....---..290-----------------.--......300--------....--------...310-........-.320.....-------..330.......340..---------.----....350--...-.....360-----.........370.......380....-------...390.......400...-----....410...----....420-----------........-430-.----..---......440-.------.......450.......460......------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------M
N
A
E
E
K
K
G
L
Q
R
A
I
E
E
I
T
E
I
A
K
GFGLDFY
P
M
R
---------
Y
-EIC-
P
A
E
I
I
YTFGAYGM-----------PTRFS
H
W
-
S
F
G
K
Q
F
----------
H
K
M
K
L
H
Y
DL-
G
L
S
K
I
Y
E
--
L
V
INSDP
C
Y
-----------------
A
F
L
LDSN
S
------
L
-
I
Q
N
K
L
I
V
-------
A
H
V
L
A
-----------
H
C
D
F
F
KN----------N----
C
R
FQ
N
T
K
---
R
D
M
V
E
S
M
A
A
T
--
A
E
R
I
------
K
H
Y
E
Q
VH
G
I
--------
K
E
V
----
E
S
F
L
D
A
I
---
L
------
S
I
Q
E
HI
D
P
-
S
LVRP
K
L
Q
W
---SVD
D
E
E
E
E
I
E
E
AA-T
P
----------
Y
D
D
L
W---SLDEK
K
P
K
K
Q
--
V
K
KSKK--PFPPRP-E----------K
D
I
L
L
F
I
E
E
HSRE-------L
E
P
W
Q
--
R
D
I
L
T
M
M
R
E
---
E
M
L
Y
F
WP
Q
L
E
T
K
------------------------------------
I
M
------------
N
-
E
----------------------------------
G
W
A
S
Y
W
H
Q
R
I
I
----------------------------
R
E
LDLTS-
D
E
-------
A
I
E
F
A
KLN---AGVVQ-----------------P--SKTGIN
P
Y
Y
--------
L
G
L
K
--------
I
F
E
D
---
I
E
K
RYNN
P
-
T
E
E
M
K
KMGV-------QPDS
G
R
E
K
M
F
E
V
R
E
I
E
S
---------
D
----
I
S
F
I
R
N
---
Y
L
T
-
K
E
L
V
M
R
-------
E
D
L
Y
L
F
Q
KQGR
D
Y
K
I
I
D
K
Q
W
K
S
V
R
D
Q
-------
L
V
S
M
R
VNGGF
P
Y
L
T
VNDGD-----YMKNN
E
L
Y
I
K
----
H
WYEGI------------
E
L
D
L
K
Y
L
E
-
K
---
V
----
L
P
---
Y
L
F
Q
L
WGR--
S
------
V
H
I
E
S
VLEDK
E
V
M
F
SYDGKGVHRRYL------------------------
36
Fugue
58.56
16%
-59
- C7 -
4PE2
2
MALE_ECOLI
A:
[3-498]
IEEG
K
L
V
I
W
I
N
GDKG
Y
N
G
L
A
E
V
G
K
K
F
E
K
D
TG
I
K
V
T
V
E
H
P
D
K
L
E
E
K
F
P
Q
V
A
A
T
G
D
G
P
D
I
I
F
W
A
---------------------
H
D
R
F
G
G
Y
A
Q
-----------
S
G
L
L
A
E
I
-
T
P
D
K
A
F
----------
Q
D
-
K
L
-
Y
P
F
-
T
W
D
A
V
R
Y
----
N
G
K
L
I
A
Y
-----------------
P
I
A
V
E
A
L
S
------
L
-
I
Y
N
K
D
L
L
PNPPKTW
E
E
I
P
A
-----------
L
D
K
E
L
K
A
----------
K
GKSA
L
M
F
N
L
Q
E
---
P
Y
F
T
W
P
L
I
A
A
D
G
G
Y
A
F
------
K
Y
E
N
G
K
Y
D
I
--------
K
D
V
GVDN
A
G
A
K
A
G
L
---
T
------
F
L
V
D
L
I
K
N
-
K
H
M
N
A
D
T
D
Y
---
S
I
A
E
A
A
F
N
K
G
E
T
A
-
M
T
----------
I
N
G
P
W
---
A
W
S
N
I
D
T
S
K
V
--
N
Y
G
V
T
V
L
P
T
F
K
G
Q
P
-
S
----------
K
P
F
V
G
V
L
S
A
G
I
N
A
-------
A
S
P
-
N
--
K
E
L
A
K
E
F
L
E
---
N
Y
L
L
T
D
E
G
L
E
A
V
------------------------------------
N
K
------------
D
-
K
----------------------------------
P
L
G
A
V
A
L
K
S
Y
E
----------------------------
E
E
L
A
K
D
P
-
R
I
-------
A
A
T
M
E
N
A
Q
---
K
G
E
I
M
-----------------
P
--
N
I
P
Q
M
S
A
F
W
--------
Y
A
V
R
T
-------
A
V
I
N
---
A
A
S
G
R
Q
T
V
-
D
E
A
L
K
D
A
Q
T
-------
N
A
A
A
S
N
I
N
K
A
K
V
A
S
V
E
S
---------
D
----
Y
S
S
V
K
S
---
A
A
L
-
S
Y
Y
S
D
K
-------
N
T
M
P
----
P
S
G
E
L
D
A
L
E
T
Y
M
D
T
L
P
D
K
----------
A
D
I
G
G
G
Y
K
L
L
L
V
N
------------
N
K
L
A
L
K
I
G
DG
T
A
A
D
S
V
------------
T
L
T
K
A
Q
I
E
-
K
---
L
----
L
S
---
D
I
---
G
P
K
--
K
------
I
Y
T
E
N
T
L
K
T
E
L
Q
K
N
S
T
L
K
D
G
T
L
Y
I
V
L
IDN---------------------
33
Fugue
51.56
19%
-81
- C6 -
1YT3
11
RND_ECOLI
A:
[1-375]
---------------------------------
M
N
Y
Q
M
I
T
T
-
D
D
A
L
A
S
L
C
E
A
V
R
A
F
P
--------------------------
A
I
A
L
D
T
E
F
V
-----------
R
T
R
-----
T
Y
Y
P
Q
L
----------
G
L
I
Q
L
F
D
G
E
-
H
L
A
L
I
D
P
--
L
G
I
T
D
W
S
P
L
-----------------
K
A
I
L
R
D
P
S
------
I
----
T
K
F
L
-------
H
A
G
S
E
-----------
D
L
E
V
F
L
N
----------
V
----
F
G
E
L
P
Q
P
---
L
I
D
T
Q
I
L
A
A
F
--
C
G
R
P
------
M
S
W
G
---
F
A
--------
S
M
V
----
E
E
Y
S
G
V
T
---
L
------
D
K
S
E
S
R
T
D
-
W
L
A
R
P
L
----------
T
E
R
Q
C
E
Y
A
A
--------------
A
D
V
W
---
Y
L
L
P
I
T
A
K
L
M
--
V
E
T
E
A
S
--
G
W
L
P
A
A
-
L
----------
D
E
C
R
L
M
Q
M
R
R
Q
E
V
-------
V
A
P
E
D
AW
R
D
I
T
N
-----------
A
W
Q
L
R
T
R
Q
------------------------------------
L
A
------------
C
-
L
----------------------------------
Q
L
L
A
D
W
R
L
R
K
A
----------------------------
R
E
R
D
L
A
V
-
N
F
-------
V
V
R
----------------------------------------------------
E
E
--------
H
L
W
S
---
V
A
R
Y
M
P
G
S
-
L
G
E
L
D
S
L
G
L
----------
S
G
S
E
I
R
F
H
G
K
T
L
L
A
---------
L
----
V
E
K
A
Q
T
----
L
P
-
E
D
A
L
P
Q
-------
P
M
L
N
L
M
D
M
P
G
-----
Y
R
K
A
F
K
A
I
K
S
L
-------
I
T
D
V
S
E
T
H
K
I
S
A
E
L
L
--
A
S
-----
R
R
Q
I
N
Q
L
L
N
W
----
H
W
------------------
K
L
K
P
Q
N
-
N
--------
L
P
---
E
L
I
S
G
W
R
G
--
E
------
L
M
A
E
A
L
---
H
N
L
L
Q
E
Y
P
Q
--------------------------------
31
Fugue
46.69
14%
-120
* C8 *
5EZM
30
?
A:
[28-578]
-------SAA
T
G
W
V
V
L
F
V
A
V
A
L
V
V
W
F
V
S
L
D
MRH
L
V
G
P
D
E
G
R
Y
A
E
I
S
R
E
M
F
A
S
G
D
W
V
T
I
R
Y
N
A
L
K
---------
Y
F
E
K
P
-
P
F
H
M
W
V
T
V
V
G
Y
E
L
FGLG
E
W
Q
A
R
L
A
V
A
L
S
G
L
L
-
G
I
G
V
S
M
----------
M
A
A
R
R
W
F
G
A
-
R
A
A
A
F
T
G
--
L
A
L
L
A
A
P
M
W
-----------------
S
V
A
A
H
F
N
T
------
L
D
M
T
L
A
G
V
M
-------
S
C
V
L
A
-----------
F
M
L
M
G
Q
H
----------
P
----
D
A
S
V
A
A
R
---
R
G
W
M
V
A
C
W
A
A
--
M
G
V
A
------
I
L
T
K
G
L
V
G
I
--------
A
L
P
----
G
L
V
L
V
V
Y
---
T
------
L
V
T
R
--
D
W
-
G
L
W
R
R
---
L
---
H
L
A
L
G
V
V
V
M
L
V
I
T
-
V
P
----------
W
F
Y
L
V
---
S
V
R
N
---------------------
P
-
E
----------
F
P
N
F
F
F
I
H
E
H
W
Q
R
RSGSVFY
F
L
P
L
V
--
I
G
G
F
L
P
W
A
G
---
I
F
P
K
L
W
T
A
M
R
A
R
------------------------------------
F
R
------------
P
-
A
----------------------------------
L
M
A
G
I
W
A
I
A
I
F
----------------------------
V
F
F
S
I
S
R
-
S
K
LPGYIVP
V
I
P
A
L
G
I
L
---
A
G
V
A
L
-----------------
D
R
L
S
P
R
S
W
G
K
Q
L
--------
I
G
M
A
--------
I
V
A
A
---
C
G
L
L
A
S
P
V
-
V
A
T
L
N
A
N
H
I
-------
P
N
S
F
Y
R
A
Y
A
V
W
V
A
V
A
F
V
---------
V
M
L
L
G
I
A
V
A
R
L
---
L
L
R
-
R
G
V
L
P
S
-------
V
A
V
Y
A
M
G
M
Y
L
G
F
T
V
A
L
L
G
H
E
T
V
G
R
P
A
S
GADI
A
P
Q
I
A
Q
K
L
T
P
E
M
P
L
Y
G
V
Q
M
L
D
HT
L
P
F
Y
L
R
H
P
L
M
M
V
G
----
Q
A
D
E
L
T
------------
F
G
A
T
V
E
P
Q
-
R
---
V
----
V
P
D
V
D
S
F
T
K
L
W
K
N
--
G
Q
P
A
M
A
V
M
S
P
D
T
Y
L
A
L
A
P
T
L
S
M
Y
V
V
A
R
D
W
R
R
V
V
V
A
NVASLAGPQ-------------
34
Fugue
42.56
16%
-82
- C5 -
4XMM
-
NUP85_YEAST
D:
[47-744]
----------------ILVPMTVNDQPIEKNGD
K
M
P
L
K
F
K
L
G
P
L
S
Y
Q
N
M
A
F
I
T
A
K
D
K
Y
K
L
Y
P
V
R
IPRLDTS
K
E
F
-
S
A
Y
-
V
S
G
L
F
E
I
Y
R
D
L
G
D
-----------
D
R
V
F
N
V
V
N
S
N
F
A
K
E
----------
H
N
A
T
V
N
L
A
M
E
A
I
L
N
E
L
E
--
V
F
I
G
R
V
K
D
Q
-----------------
D
G
R
V
N
R
F
Y
------
E
-
L
E
E
S
L
T
V
-------
L
N
C
L
R
-----------
T
M
Y
F
I
L
D
----------
G
----
Q
D
V
E
E
N
R
---
S
E
F
I
E
S
L
L
N
W
--
I
N
R
S
DGEPD
E
E
Y
I
E
Q
V
F
S
V
AGKKVFET
Q
Y
F
----
W
K
L
L
N
Q
L
---
V
L
R
GL
L
S
Q
A
I
G
C
I
E
R
-
S
D
L
L
P
Y
L
S
D
---
T
C
A
V
S
F
D
A
V
S
D
S
I
-
E
L
----------
L
K
Q
Y
P
KDS
S
S
T
F
R
E
W
K
N
L
--
V
L
K
L
S
Q
--
A
F
G
S
S
A
-
T
DIS
G
E
L
R
D
Y
I
E
D
F
L
L
V
I
G
G
N
Q
R
K
-------
I
L
Q
Y
S
--
R
T
W
Y
E
S
F
C
G
---
F
L
L
Y
Y
I
P
S
L
E
L
S
A
E
Y
L
Q
M
S
L
E
A
NVVDITNDW
E
Q
P
C
V
D
I
I
S
GKIHSI
L
P
V
M
------------
E
-
S
L
D
S
C
T
A
A
F
T
A
M
I
C
E
A
K
GLIENIFEGLEDLFSYRN
G
M
A
S
Y
M
L
N
S
F
A
----------------------------
F
E
L
C
S
L
G
-
D
K
---------
E
L
W
P
V
A
---
I
G
L
I
A
-----------------
L
--
S
A
T
G
--
T
R
S
--------
A
K
K
M
--------
V
I
A
E
---
L
L
P
H
Y
P
F
V
-
T
N
D
D
I
E
W
M
L
-------
S
I
C
V
E
W
R
L
P
E
I
A
K
E
I
Y
T
---------
T
----
L
G
N
I
E
S
---
I
A
N
-
F
S
L
V
K
S
-------
Y
S
W
L
L
F
E
A
S
C
M
E
G
Q
K
V
L
N
A
I
V
S
K
D
D
V
-------
I
I
P
Q
D
I
L
V
T
N
S
M
R
Q
T
L
A
P
Y
-----
A
V
L
S
Q
F
Y
D
R
E
----
D
W
G
Q
A
L
------------
R
L
L
L
L
L
I
E
F
H
---
Y
----
L
V
---
L
L
V
A
K
F
L
Y
--
P
------
I
F
E
D
S
V
A
T
V
I
E
V
I
E
T
K
W
S
N
L
Y
E
T
I
I
E
A
D
K
SA
T
L
L
K
N
L
R
K
K
L
N
F
K
L
C
Q
A
F
M
32
Fugue
40.60
13%
-75
* C9 *
2QMI
-
?
A:
[1-447]
------------------------------------
M
D
V
G
K
L
E
S
F
I
V
E
K
M
A
E
R
K
V
P
G
I
S
I
S
I
I
K
---------
D
-
G
D
V
-
V
Y
A
K
G
F
G
Y
R
N
V
E
A
-----------
R
L
P
S
T
P
E
-
T
I
Y
G
I
G
----------
S
I
T
K
S
F
T
A
L
-
A
I
M
K
L
V
E
E
G
G
L
S
L
D
D
P
V
E
-----------------
K
F
V
N
I
K
L
R
------
P
-
F
G
E
P
V
T
V
-------
H
H
L
L
T
-----------
H
S
S
G
I
P
S
----------
L
---------------
G
Y
A
E
A
F
I
D
G
--
M
V
G
G
------
D
N
W
L
P
V
S
T
P
--------
E
E
T
----
I
A
F
A
R
D
M
---
E
------
K
W
A
V
A
-
K
P
-
G
E
R
F
F
Y
L
N
T
---
G
Y
V
L
L
G
K
I
I
E
K
V
S
G
V
S
----------
Y
E
E
Y
I
---
K
K
K
I
L
E
P
L
G
M
--
N
R
S
Y
F
F
--
K
E
E
V
E
K
-
D
----------
K
D
V
A
M
G
Y
I
L
D
K
E
G
-------
R
L
V
P
Q
--
P
F
P
Y
G
I
T
A
D
---
G
G
L
L
S
--------------------------------------------
S
------------
V
-
L
----------------------------------
D
L
A
K
Y
L
K
M
Y
I
E
----------------------------
R
D
E
S
I
V
S
-
K
E
-------
Y
I
E
K
M
E
T
S
---
Y
I
K
V
P
-----------------
W
--
E
I
F
G
G
E
G
Y
G
--------
Y
G
L
I
--------
I
Y
P
N
---
F
L
G
-------
E
K
L
V
G
H
S
G
-------
S
V
G
M
Y
T
G
Y
I
G
Y
I
P
E
K
K
I
---------
G
----
V
A
V
L
E
N
SSG
Y
P
P
-
S
Y
I
A
M
Y
-------
A
L
A
L
L
L
G
K
N
P
E
K
E
L
P
F
I
Y
R
E
R
I
L
K
K
V
-------
E
G
R
Y
M
G
Y
K
G
T
I
K
F
E
V
K
V
D
G
-------
D
V
V
Y
L
R
A
L
----
G
R
A
F
T
Y
------------
T
I
P
L
F
P
E
V
-
L
EED
F
----
I
K
---
C
Y
T
L
S
N
G
R
--
K
------
M
Y
A
E
F
Y
I
K
D
N
K
V
D
L
I
F
E
R
Y
R
L
I
K
S
--------------------------
35
Fugue
38.77
18%
-65
- C3 -
4S3Q
7
MALQ_ECOLI
A:
[2-691]
------ES
K
R
L
D
N
A
A
L
A
A
GISP
N
Y
I
N
AHG
K
P
Q
S
I
S
A
E
T
K
R
R
L
L
D
A
M
H
Q
T
P
V
P
N
V
M
V
Y
T
S
G
K
K
M
P
---------
M
-
V
V
E
G
S
G
E
Y
S
W
L
L
T
T
E
E
G
-----------
T
Q
Y
K
G
H
V
-
T
G
G
K
A
F
N
L
P
TKLPE
G
Y
H
T
L
T
L
T
Q
D
--
D
Q
R
A
H
C
R
--
V
I
V
A
P
K
R
C
Y
EP
Q
A
L
L
N
K
Q
K
L
W
G
A
C
V
Q
L
Y
T
L
R
S
E
K
NWGIGD
F
-
G
D
L
K
A
M
L
-------
V
D
V
A
K
R
GGS
F
I
G
L
N
PI
H
A
L
Y
P
A
N
PESASPYSPS
S
----
R
R
W
L
N
V
I
YID
V
N
A
V
E
D
F
H
L
S
--
E
E
A
Q
------
A
W
W
Q
L
P
T
T
Q
--------
Q
T
L
----
Q
Q
A
R
D
A
D
WVD
Y
------
S
T
V
T
A
L
K
M
-
T
A
L
R
M
A
W
K
G
F
A
Q
R
D
D
E
Q
M
A
A
F
R
Q
F
V
-
A
E
Q
G
D
S
L
F
W
Q
A
A
F
D
A
L
H
---
A
Q
Q
V
K
E
D
E
M
R
WG
W
P
A
W
P
E
--
M
Y
Q
N
V
D
-
S
----------
P
E
V
R
Q
F
C
E
E
H
R
D
D
-------
V
D
-
F
Y
--
L
W
L
Q
W
L
A
Y
S
---
Q
F
A
A
C
W
E
I
S
Q
G
Y
------------------------------------
E
M
PIG
L
Y
R
D
L
A
VGV
A
-
E
----------------------------------
G
G
A
E
T
W
C
D
R
E
L
YCLK
A
S
V
G
A
P
PDILGPLGQNWG
L
P
P
M
D
P
H
I
I
T
A
R
A
Y
E
P
-------
F
I
E
L
L
R
A
N
M
QN
C
G
A
L
R
I
D
HVMSMLRLWWIPYGE
T
--
A
D
Q
G
A
Y
V
H
Y
P
V
D
D
L
L
S
I
L
A
L
E
S
K
R
H
R
C
M
V
I
G
E
D
---
L
G
T
V
P
V
E
I
-
V
G
K
L
R
S
S
G
V
Y
S
Y
K
V
LY
F
E
N
D
H
E
K
T
F
R
A
P
K
A
Y
P
E
Q
S
M
A
V
AATH
D
----
L
P
T
L
R
G
---
Y
W
E
C
G
D
L
T
L
G
-------
K
T
L
G
L
Y
P
D
E
V
V
L
R
G
L
Y
Q
D
R
E
L
A
K
Q
G
L
-------
L
D
A
L
H
K
Y
G
C
L
P
K
R
A
G
H
K
A
S
-----
L
M
S
M
T
P
T
L
N
R
----
G
L
Q
R
Y
I
A
D
SNSA
L
L
G
L
Q
P
E
D
W
L
D
M
A
E
-
P
---
V
NIPG
T
S
---
Y
Q
Y
K
N
W
R
R
KL
S
------
A
T
L
E
S
M
F
A
D
D
G
V
N
K
L
L
K
D
L
D
R
R
R
R
S
A
H-----------------------
28
HHSearch
35.11
40%
-213
- C2 -
1N0X
1
?
P:
[6-14]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
F
S
D
---
L
E
N
R
C
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
34.96
11%
-70
- C8 -
4K1P
1
?
A:
[16-360]
------------------------------------
I
A
P
N
T
L
S
N
S
I
R
M
L
G
--
S
Q
S
P
L
I
Q
A
Y
G
L
V
---------
I
-
L
Q
Q
-
P
------------------------------------------------------
D
I
-
K
V
N
A
M
------------------------------------------------------------
S
S
L
T
N
-----------
H
Q
K
F
A
K
A
----------
N
----
V
R
E
W
I
D
-----
E
Y
N
P
K
L
I
D
L
--
N
Q
E
M
------
M
R
Y
-----
S
--------
I
R
F
----
N
S
Y
Y
S
K
L
---
Y
------
E
L
A
G
N
I
N
E
D
E
Q
S
K
A
D
F
T
N
---
A
Y
G
K
L
Q
L
Q
V
Q
S
I
Q
-
E
N
----------
M
E
Q
D
L
---
L
-
E
L
N
R
F
K
T
V
--
L
D
K
D
S
N
--
N
L
S
I
K
A
-
D
----------
E
A
I
K
T
L
--
Q
G
S
G
D
-------
I
V
K
L
R
--
E
D
I
K
R
I
Q
G
E
---
I
Q
A
E
L
T
T
I
L
N
R
P
------------------------------------
Q
E
------------
I
I
K
----------------------------------
G
S
I
N
I
G
K
Q
V
F
T
----------------------------
I
T
T
--
K
T
-
I
D
-------
F
V
S
I
G
T
L
S
---
N
E
I
V
N
-----------------
A
--
A
D
------------------
S
--------
Q
T
R
E
---
A
A
L
R
I
Q
Q
K
-
Q
K
E
L
L
P
L
I
Q
-------
K
L
S
Q
T
E
A
E
A
T
Q
I
T
F
V
E
D
---------
Q
----
V
S
S
F
T
E
---
L
I
D
-
R
Q
I
T
T
L
-------
E
T
L
------
L
T
D
W
K
V
L
N
N
N
M
I
Q
I
Q
K
N
-------
V
E
E
---------
G
T
Y
T
D
S
S
-----
L
L
Q
K
H
F
N
Q
I
K
----
K
V
S
D
E
M
------------
N
---
K
Q
T
N
-
Q
---
F
----
E
D
---
Y
V
T
N
V
E
V
H
-----------------------------------------------------------
39
Fugue
34.00
14%
-64
- C9 -
4K36
5
ANSME_CLOP1
A:
[2-392]
-----------------------------------------------------
P
P
L
S
L
L
I
K
P
A
S
---------
S
-
G
-
C
-
N
L
K
C
T
Y
C
F
------------------
Y
H
S
L
S
-
D
N
V
K
S
Y
----------
G
I
M
R
--
D
E
V
-
L
E
S
M
V
K
R
--
V
L
N
E
A
N
G
H
C
-----------------
S
F
A
F
Q
G
G
-----------------------
E
P
T
L
A
-----------
G
L
E
F
F
E
K
----------
L
----
M
E
L
Q
R
K
H
---
N
Y
-------
K
--
N
L
K
I
------
Y
N
S
L
Q
T
N
G
T
--------
L
I
D
----
E
S
W
A
K
F
L
---
S
------
E
N
----------
K
F
L
V
G
L
---
S
M
D
G
P
K
E
I
H
N
L
N
R
-
K
-------------------
D
C
C
G
L
D
T
F
S
K
--
V
E
R
A
A
E
--
L
F
K
K
Y
K
V
E
----------
F
N
I
L
C
V
V
T
S
N
T
A
R
----------
H
V
--
N
K
V
Y
K
Y
F
K
E
K
DF
K
F
L
Q
F
I
N
C
L
D
P
L
------------------------------------
Y
E
------------
E
-
K
----------------------------------
G
---------
K
----------------------------
Y
N
Y
S
L
K
P
-
K
D
-------
Y
T
K
F
L
K
N
L
---
F
D
F
W
Y
-----------------
E
--
D
F
L
N
G
N
R
V
S
--------
I
--
R
--------
Y
F
D
G
---
L
L
E
T
I
L
L
---
G
K
S
S
S
C
G
M
-------
N
G
T
C
T
C
Q
F
V
V
E
---
S
D
G
---------
S
----
V
Y
P
C
D
F
---
Y
V
L
-
D
K
W
R
L
G
NIQDMT
M
K
E
L
F
E
T
N
K
N
H
E
F
I
K
L
S
F
K
V
H
E
E
C
K
K
C
-------
K
W
F
R
L
C
K
G
G
C
R
R
C
R
D
S
K
---------
E
D
S
A
L
E
L
N
----
Y
Y
C
Q
S
Y
------------
K
E
F
F
E
Y
A
F
-
P
---
R
----
L
I
---
N
V
A
N
N
--------------
I
V
D
K
L
A
A
A
L
E
H
H
H
H
H
H
--------------------------------
13
PsiBlast_PDB
32.09
28%
-72
- C10 -
4JPS
-
B:
[177-274]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Q
-----------------
M
--
K
R
T
A
I
E
A
F
N
--------
E
T
I
K
--------
I
F
E
E
Q
C
Q
T
Q
E
R
Y
S
K
E
Y
I
E
K
F
K
R
E
G
N
-------
E
K
E
I
Q
R
-
I
M
H
N
Y
D
K
L
K
S
---------
R
----
I
S
E
I
------
I
D
-
S
R
R
R
L
E
-------
E
D
L
---
K
K
Q
A
A
E
Y
R
E
I
D
K
R
M
N
S
I
K
P
D
-------
L
I
Q
L
R
---------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
32.07
28%
-80
- C10 -
4L1B
-
B:
[186-283]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Q
-----------------
M
--
K
R
T
A
I
E
A
F
N
--------
E
T
I
K
--------
I
F
E
E
Q
C
Q
T
Q
E
R
Y
S
K
E
Y
I
E
K
F
K
R
E
G
N
-------
E
K
E
I
Q
R
-
I
M
H
N
Y
D
K
L
K
S
---------
R
----
I
S
E
I
------
I
D
-
S
R
R
R
L
E
-------
E
D
L
---
K
K
Q
A
A
E
Y
R
E
I
D
K
R
M
N
S
I
K
P
D
-------
L
I
Q
L
R
---------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
31.91
28%
-100
- C10 -
5DXU
-
B:
[47-144]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Q
-----------------
M
--
K
R
T
A
I
E
A
F
N
--------
E
T
I
K
--------
I
F
E
E
Q
C
Q
T
Q
E
R
Y
S
K
E
Y
I
E
K
F
K
R
E
G
N
-------
E
T
E
I
Q
R
-
I
M
H
N
Y
E
K
L
K
S
---------
R
----
I
S
E
I
------
V
D
-
S
R
R
R
L
E
-------
E
D
L
---
K
K
Q
A
A
E
Y
R
E
I
D
K
R
M
N
S
I
K
P
D
-------
L
I
Q
L
R
---------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
31.40
28%
-67
- C10 -
3HIZ
-
P85A_HUMAN
B:
[477-574]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Q
-----------------
M
--
K
R
T
A
I
E
A
F
N
--------
E
T
I
K
--------
I
F
E
E
Q
C
Q
T
Q
E
R
Y
S
K
E
Y
I
E
K
F
K
R
E
G
N
-------
E
K
E
I
Q
R
-
I
M
H
N
Y
D
K
L
K
S
---------
R
----
I
S
E
I
------
I
D
-
S
R
R
R
L
E
-------
E
D
L
---
K
K
Q
A
A
E
Y
R
E
I
D
K
R
M
N
S
I
K
P
D
-------
L
I
Q
L
R
---------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
31.27
28%
-82
- C10 -
4YKN
-
P85A_HUMAN (first)
A:
[167-360]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Q
-----------------
M
--
K
R
T
A
I
E
A
F
N
--------
E
T
I
K
--------
I
F
E
E
Q
C
Q
T
Q
E
R
Y
S
K
E
Y
I
E
K
F
K
R
E
G
N
-------
E
K
E
I
Q
R
-
I
M
H
N
Y
D
K
L
K
S
---------
R
----
I
S
E
I
------
I
D
-
S
R
R
R
L
E
-------
E
D
L
---
K
K
Q
A
A
E
Y
R
E
I
D
K
R
M
N
S
I
K
P
D
-------
L
I
Q
L
R
---------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
31.00
28%
-79
- C10 -
4WAF
-
B:
[183-280]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Q
-----------------
M
--
K
R
T
A
I
E
A
F
N
--------
E
T
I
K
--------
I
F
E
E
Q
C
Q
T
Q
E
R
Y
S
K
E
Y
I
E
K
F
K
R
E
G
N
-------
E
K
E
I
Q
R
-
I
M
H
N
Y
D
K
L
K
S
---------
R
----
I
S
E
I
------
I
D
-
S
R
R
R
L
E
-------
E
D
L
---
K
K
Q
A
A
E
Y
R
E
I
D
K
R
M
N
S
I
K
P
D
-------
L
I
Q
L
R
---------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
30.83
28%
-73
- C10 -
3HHM
-
B:
[156-253]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Q
-----------------
M
--
K
R
T
A
I
E
A
F
N
--------
E
T
I
K
--------
I
F
E
E
Q
C
Q
T
Q
E
R
Y
S
K
E
Y
I
E
K
F
K
R
E
G
N
-------
E
K
E
I
Q
R
-
I
M
H
N
Y
D
K
L
K
S
---------
R
----
I
S
E
I
------
I
D
-
S
R
R
R
L
E
-------
E
D
L
---
K
K
Q
A
A
E
Y
R
E
I
D
K
R
M
N
S
I
K
P
D
-------
L
I
Q
L
R
---------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
30.59
28%
-68
- C10 -
4L2Y
1
B:
[186-283]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Q
-----------------
M
--
K
R
T
A
I
E
A
F
N
--------
E
T
I
K
--------
I
F
E
E
Q
C
Q
T
Q
E
R
Y
S
K
E
Y
I
E
K
F
K
R
E
G
N
-------
E
K
E
I
Q
R
-
I
M
H
N
Y
D
K
L
K
S
---------
R
----
I
S
E
I
------
I
D
-
S
R
R
R
L
E
-------
E
D
L
---
K
K
Q
A
A
E
Y
R
E
I
D
K
R
M
N
S
I
K
P
D
-------
L
I
Q
L
R
---------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
30.11
28%
-74
- C10 -
5FI4
1
B:
[183-280]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Q
-----------------
M
--
K
R
T
A
I
E
A
F
N
--------
E
T
I
K
--------
I
F
E
E
Q
C
Q
T
Q
E
R
Y
S
K
E
Y
I
E
K
F
K
R
E
G
N
-------
E
K
E
I
Q
R
-
I
M
H
N
Y
D
K
L
K
S
---------
R
----
I
S
E
I
------
I
D
-
S
R
R
R
L
E
-------
E
D
L
---
K
K
Q
A
A
E
Y
R
E
I
D
K
R
M
N
S
I
K
P
D
-------
L
I
Q
L
R
---------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
29.96
28%
-65
- C10 -
5DXH
-
P85A_BOVIN
B:
[47-144]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Q
-----------------
M
--
K
R
T
A
I
E
A
F
N
--------
E
T
I
K
--------
I
F
E
E
Q
C
Q
T
Q
E
R
Y
S
K
E
Y
I
E
K
F
K
R
E
G
N
-------
E
T
E
I
Q
R
-
I
M
H
N
Y
E
K
L
K
S
---------
R
----
I
S
E
I
------
V
D
-
S
R
R
R
L
E
-------
E
D
L
---
K
K
Q
A
A
E
Y
R
E
I
D
K
R
M
N
S
I
K
P
D
-------
L
I
Q
L
R
---------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
29.94
28%
-82
- C10 -
2RD0
-
P85A_HUMAN
B:
[477-583]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Q
-----------------
M
--
K
R
T
A
I
E
A
F
N
--------
E
T
I
K
--------
I
F
E
E
Q
C
Q
T
Q
E
R
Y
S
K
E
Y
I
------------------
I
Q
R
-
I
M
H
N
Y
D
K
L
K
S
---------
R
----
I
S
E
I
------
I
D
-
S
R
R
R
L
E
-------
E
D
L
---
K
K
Q
A
A
E
Y
R
E
I
D
K
R
M
N
S
I
K
P
D
-------
L
I
Q
L
R
---------------------------------------------------------------------------------------------------------------------------------------------