@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu09450: (2016-06-14 )
MNPMDRQTEGQEPQHQDRQPGIESKMNPLPLSEDEDYRGSGKLKGKVAIITGGDSGIGRAAAIAFAKEGADISILYLDEHSDAEETRKRIEKENVRCLLIPGDVGDENHCEQAVQQTVDHFGKLDILVNNAAEQHPQDSILNISTEQLEKTFRTNIFSMFHMTKKALPHLQEGCAIINTTSITAYEGDTALIDYSSTKGAIVSFTRSMAKSLADKGIRVNAVAPGPIWTPLIPATFPEEKVKQHGLDTPMGRPGQPVEHAGAYVLLASDESSYMTGQTIHVNGGRFIST
Atome Classification :
(22 SA)
.........10........20........30........40........50........60........70.......-.80........90........100.......110.......120-----........130--.......140.....-..150.......160.......170...--......180.......190.......200.......210.......220.......230---.-........240.-......250.......260.......270.......280.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MNPMDRQTEGQEPQHQDRQPGIESKMNPLPLSEDEDYRGSGKL
K
G
K
V
A
I
I
TGGDSGI
G
R
A
A
A
I
A
FAKEGA
D
I
S
I
L
Y
LD-EHS
D
A
E
E
T
R
K
R
I
E
KEN
V
R
C
L
L
I
PGDVG
D
E
N
H
C
E
Q
A
V
Q
Q
T
V
D
HF------GK
L
D
I
L
VNN
A
A
--EQHPQDSILNI
S
T
E
Q
-
L
E
K
T
F
R
T
N
I
F
S
M
F
H
M
T
K
K
A
L
P
H
L
--
Q
EG--
C
A
I
I
N
T
T
S
I
T
A
YEG
D
T
A
L
I
DYSSTK
G
A
I
V
S
F
T
R
S
M
A
K
S
L
A
DKG
I
R
V
N
A
VAPGPIWTP-----L-IPATF
P
E
E
K
V
K
Q-HGLDTPMGRPGQPVEHA
G
A
Y
V
L
L
ASDESSYMTG
Q
T
I
H
VNG
G
R
F
IST
1
PsiBlast_PDB
78.05
65%
-58
- C1 -
3I3O
5
?
A:
[16-290]
-------------
Q
H
Q
N
K
Q
P
G
I
E
S
L
M
N
P
L
P
Q
F
E
D
P
N
Y
K
G
S
E
K
L
K
G
K
N
V
L
I
T
G
G
D
S
G
I
G
R
A
V
S
I
A
F
A
K
E
G
A
N
I
A
I
A
Y
L
D
-
E
E
G
D
A
N
E
T
K
Q
Y
V
E
K
E
G
V
K
C
V
L
L
P
G
D
L
S
D
E
Q
H
C
K
D
I
V
Q
E
T
V
R
Q
L
------
G
S
L
N
I
L
V
N
N
V
A
--
Q
Q
Y
P
Q
Q
G
L
E
Y
I
T
A
E
Q
-
L
E
K
T
F
R
I
N
I
F
S
Y
F
H
V
T
K
A
A
L
S
H
L
--
K
Q
G
--
D
V
I
I
N
T
A
S
I
V
A
Y
E
G
N
E
T
L
I
D
Y
S
A
T
K
G
A
I
V
A
F
T
R
S
L
S
Q
S
L
V
Q
K
G
I
R
V
N
G
V
A
P
G
P
I
W
T
P
-----
L
-
I
P
S
S
F
D
E
K
K
V
S
Q
-
F
G
S
N
V
P
M
Q
R
P
G
Q
P
Y
E
L
A
P
A
Y
V
Y
L
A
S
S
D
S
S
Y
V
T
G
Q
M
I
H
V
N
G
G
V
I
V
N
-
2
PsiBlast_PDB
76.91
65%
-57
- C1 -
3IJR
5
?
A:
[16-290]
-------------
Q
H
Q
N
K
Q
P
G
I
E
S
L
M
N
P
L
P
Q
F
E
D
P
N
Y
K
G
S
E
K
L
K
G
K
N
V
L
I
T
G
G
D
S
G
I
G
R
A
V
S
I
A
F
A
K
E
G
A
N
I
A
I
A
Y
L
D
-
E
E
G
D
A
N
E
T
K
Q
Y
V
E
K
E
G
V
K
C
V
L
L
P
G
D
L
S
D
E
Q
H
C
K
D
I
V
Q
E
T
V
R
Q
L
------
G
S
L
N
I
L
V
N
N
V
A
--
Q
Q
Y
P
Q
Q
G
L
E
Y
I
T
A
E
Q
-
L
E
K
T
F
R
I
N
I
F
S
Y
F
H
V
T
K
A
A
L
S
H
L
--
K
Q
G
--
D
V
I
I
N
T
A
S
I
V
A
Y
E
G
N
E
T
L
I
D
Y
S
A
T
K
G
A
I
V
A
F
T
R
S
L
S
Q
S
L
V
Q
K
G
I
R
V
N
G
V
A
P
G
P
I
W
T
P
-----
L
-
I
P
S
S
F
D
E
K
K
V
S
Q
-
F
G
S
N
V
P
M
Q
R
P
G
Q
P
Y
E
L
A
P
A
Y
V
Y
L
A
S
S
D
S
S
Y
V
T
G
Q
M
I
H
V
N
G
G
V
I
V
N
-
26
PsiBlast_CBE
76.77
65%
-56
- C1 -
3I3O
3
?
C:
[16-290]
-------------
Q
H
Q
N
K
Q
P
G
I
E
S
L
M
N
P
L
P
Q
F
E
D
P
N
Y
K
G
S
E
K
L
K
G
K
N
V
L
I
T
G
G
D
S
G
I
G
R
A
V
S
I
A
F
A
K
E
G
A
N
I
A
I
A
Y
L
D
-
E
E
G
D
A
N
E
T
K
Q
Y
V
E
K
E
G
V
K
C
V
L
L
P
G
D
L
S
D
E
Q
H
C
K
D
I
V
Q
E
T
V
R
Q
L
------
G
S
L
N
I
L
V
N
N
V
A
--
Q
Q
Y
P
Q
Q
G
L
E
Y
I
T
A
E
Q
-
L
E
K
T
F
R
I
N
I
F
S
Y
F
H
V
T
K
A
A
L
S
H
L
--
K
Q
G
--
D
V
I
I
N
T
A
S
I
V
A
Y
E
G
N
E
T
L
I
D
Y
S
A
T
K
G
A
I
V
A
F
T
R
S
L
S
Q
S
L
V
Q
K
G
I
R
V
N
G
V
A
P
G
P
I
W
T
P
-----
L
-
I
P
S
S
F
D
E
K
K
V
S
Q
-
F
G
S
N
V
P
M
Q
R
P
G
Q
P
Y
E
L
A
P
A
Y
V
Y
L
A
S
S
D
S
S
Y
V
T
G
Q
M
I
H
V
N
G
G
V
I
V
N
-
24
PsiBlast_CBE
76.41
65%
-56
- C1 -
3I3O
3
?
E:
[16-290]
-------------
Q
H
Q
N
K
Q
P
G
I
E
S
L
M
N
P
L
P
Q
F
E
D
P
N
Y
K
G
S
E
K
L
K
G
K
N
V
L
I
T
G
G
D
S
G
I
G
R
A
V
S
I
A
F
A
K
E
G
A
N
I
A
I
A
Y
L
D
-
E
E
G
D
A
N
E
T
K
Q
Y
V
E
K
E
G
V
K
C
V
L
L
P
G
D
L
S
D
E
Q
H
C
K
D
I
V
Q
E
T
V
R
Q
L
------
G
S
L
N
I
L
V
N
N
V
A
--
Q
Q
Y
P
Q
Q
G
L
E
Y
I
T
A
E
Q
-
L
E
K
T
F
R
I
N
I
F
S
Y
F
H
V
T
K
A
A
L
S
H
L
--
K
Q
G
--
D
V
I
I
N
T
A
S
I
V
A
Y
E
G
N
E
T
L
I
D
Y
S
A
T
K
G
A
I
V
A
F
T
R
S
L
S
Q
S
L
V
Q
K
G
I
R
V
N
G
V
A
P
G
P
I
W
T
P
-----
L
-
I
P
S
S
F
D
E
K
K
V
S
Q
-
F
G
S
N
V
P
M
Q
R
P
G
Q
P
Y
E
L
A
P
A
Y
V
Y
L
A
S
S
D
S
S
Y
V
T
G
Q
M
I
H
V
N
G
G
V
I
V
N
-
27
PsiBlast_CBE
75.78
65%
-58
- C1 -
3I3O
5
?
B:
[16-290]
-------------
Q
H
Q
N
K
Q
P
G
I
E
S
L
M
N
P
L
P
Q
F
E
D
P
N
Y
K
G
S
E
K
L
K
G
K
N
V
L
I
T
G
G
D
S
G
I
G
R
A
V
S
I
A
F
A
K
E
G
A
N
I
A
I
A
Y
L
D
-
E
E
G
D
A
N
E
T
K
Q
Y
V
E
K
E
G
V
K
C
V
L
L
P
G
D
L
S
D
E
Q
H
C
K
D
I
V
Q
E
T
V
R
Q
L
------
G
S
L
N
I
L
V
N
N
V
A
--
Q
Q
Y
P
Q
Q
G
L
E
Y
I
T
A
E
Q
-
L
E
K
T
F
R
I
N
I
F
S
Y
F
H
V
T
K
A
A
L
S
H
L
--
K
Q
G
--
D
V
I
I
N
T
A
S
I
V
A
Y
E
G
N
E
T
L
I
D
Y
S
A
T
K
G
A
I
V
A
F
T
R
S
L
S
Q
S
L
V
Q
K
G
I
R
V
N
G
V
A
P
G
P
I
W
T
P
-----
L
-
I
P
S
S
F
D
E
K
K
V
S
Q
-
F
G
S
N
V
P
M
Q
R
P
G
Q
P
Y
E
L
A
P
A
Y
V
Y
L
A
S
S
D
S
S
Y
V
T
G
Q
M
I
H
V
N
G
G
V
I
V
N
-
25
PsiBlast_CBE
74.21
65%
-56
- C1 -
3I3O
5
?
D:
[16-290]
-------------
Q
H
Q
N
K
Q
P
G
I
E
S
L
M
N
P
L
P
Q
F
E
D
P
N
Y
K
G
S
E
K
L
K
G
K
N
V
L
I
T
G
G
D
S
G
I
G
R
A
V
S
I
A
F
A
K
E
G
A
N
I
A
I
A
Y
L
D
-
E
E
G
D
A
N
E
T
K
Q
Y
V
E
K
E
G
V
K
C
V
L
L
P
G
D
L
S
D
E
Q
H
C
K
D
I
V
Q
E
T
V
R
Q
L
------
G
S
L
N
I
L
V
N
N
V
A
--
Q
Q
Y
P
Q
Q
G
L
E
Y
I
T
A
E
Q
-
L
E
K
T
F
R
I
N
I
F
S
Y
F
H
V
T
K
A
A
L
S
H
L
--
K
Q
G
--
D
V
I
I
N
T
A
S
I
V
A
Y
E
G
N
E
T
L
I
D
Y
S
A
T
K
G
A
I
V
A
F
T
R
S
L
S
Q
S
L
V
Q
K
G
I
R
V
N
G
V
A
P
G
P
I
W
T
P
-----
L
-
I
P
S
S
F
D
E
K
K
V
S
Q
-
F
G
S
N
V
P
M
Q
R
P
G
Q
P
Y
E
L
A
P
A
Y
V
Y
L
A
S
S
D
S
S
Y
V
T
G
Q
M
I
H
V
N
G
G
V
I
V
N
-
23
PsiBlast_CBE
74.09
65%
-62
- C1 -
3I3O
1
?
F:
[22-290]
-------------------
P
G
I
E
S
L
M
N
P
L
P
Q
F
E
D
P
N
Y
K
G
S
E
K
L
K
G
K
N
V
L
I
T
G
G
D
S
G
I
G
R
A
V
S
I
A
F
A
K
E
G
A
N
I
A
I
A
Y
L
D
-
E
E
G
D
A
N
E
T
K
Q
Y
V
E
K
E
G
V
K
C
V
L
L
P
G
D
L
S
D
E
Q
H
C
K
D
I
V
Q
E
T
V
R
Q
L
------
G
S
L
N
I
L
V
N
N
V
A
--
Q
Q
Y
P
Q
Q
G
L
E
Y
I
T
A
E
Q
-
L
E
K
T
F
R
I
N
I
F
S
Y
F
H
V
T
K
A
A
L
S
H
L
--
K
Q
G
--
D
V
I
I
N
T
A
S
I
V
A
Y
E
G
N
E
T
L
I
D
Y
S
A
T
K
G
A
I
V
A
F
T
R
S
L
S
Q
S
L
V
Q
K
G
I
R
V
N
G
V
A
P
G
P
I
W
T
P
-----
L
-
I
P
S
S
F
D
E
K
K
V
S
Q
-
F
G
S
N
V
P
M
Q
R
P
G
Q
P
Y
E
L
A
P
A
Y
V
Y
L
A
S
S
D
S
S
Y
V
T
G
Q
M
I
H
V
N
G
G
V
I
V
N
-
21
PsiBlast_CBE
72.19
65%
-58
- C1 -
3I3O
6
?
H:
[17-290]
--------------
H
Q
N
K
Q
P
G
I
E
S
L
M
N
P
L
P
Q
F
E
D
P
N
Y
K
G
S
E
K
L
K
G
K
N
V
L
I
T
G
G
D
S
G
I
G
R
A
V
S
I
A
F
A
K
E
G
A
N
I
A
I
A
Y
L
D
-
E
E
G
D
A
N
E
T
K
Q
Y
V
E
K
E
G
V
K
C
V
L
L
P
G
D
L
S
D
E
Q
H
C
K
D
I
V
Q
E
T
V
R
Q
L
------
G
S
L
N
I
L
V
N
N
V
A
--
Q
Q
Y
P
Q
Q
G
L
E
Y
I
T
A
E
Q
-
L
E
K
T
F
R
I
N
I
F
S
Y
F
H
V
T
K
A
A
L
S
H
L
--
K
Q
G
--
D
V
I
I
N
T
A
S
I
V
A
Y
E
G
N
E
T
L
I
D
Y
S
A
T
K
G
A
I
V
A
F
T
R
S
L
S
Q
S
L
V
Q
K
G
I
R
V
N
G
V
A
P
G
P
I
W
T
P
-----
L
-
I
P
S
S
F
-----
S
Q
-
F
G
S
N
V
P
M
Q
R
P
G
Q
P
Y
E
L
A
P
A
Y
V
Y
L
A
S
S
D
S
S
Y
V
T
G
Q
M
I
H
V
N
G
G
V
I
V
N
-
30
PsiBlast_CBE
68.01
44%
-56
- C1 -
3R3S
4
?
B:
[6-293]
-
D
P
T
T
Q
Y
Y
T
G
E
Y
P
K
Q
K
Q
P
A
P
G
V
Q
A
K
M
T
P
V
P
D
C
G
E
K
S
Y
V
G
S
G
R
L
K
D
R
K
A
L
V
T
G
G
D
S
G
I
G
R
A
A
A
I
A
Y
A
R
E
G
A
D
V
A
I
N
Y
L
P
A
E
E
E
D
A
Q
Q
V
K
A
L
I
E
E
C
G
R
K
A
V
L
L
P
G
D
L
S
D
E
S
F
A
R
S
L
V
H
K
A
R
E
A
L
------
G
G
L
D
I
L
A
L
V
A
G
--
K
Q
T
A
I
P
E
I
K
D
L
T
S
E
Q
-
F
Q
Q
T
F
A
V
N
V
F
A
L
F
W
I
T
Q
E
A
I
P
L
L
--
P
K
G
--
A
S
I
I
T
T
S
S
I
Q
A
Y
Q
P
S
P
H
L
L
D
Y
A
A
T
K
A
A
I
L
N
Y
S
R
G
L
A
K
Q
V
A
E
K
G
I
R
V
N
I
V
A
P
G
P
I
W
T
A
-----
L
Q
I
S
G
G
Q
T
Q
D
K
I
P
Q
-
F
G
Q
Q
T
P
M
K
R
A
G
Q
P
A
E
L
A
P
V
Y
V
Y
L
A
S
Q
E
S
S
Y
V
T
A
E
V
H
G
V
C
G
G
E
H
L
--
29
PsiBlast_CBE
67.80
44%
-55
- C1 -
3R3S
3
?
C:
[6-293]
-
D
P
T
T
Q
Y
Y
T
G
E
Y
P
K
Q
K
Q
P
A
P
G
V
Q
A
K
M
T
P
V
P
D
C
G
E
K
S
Y
V
G
S
G
R
L
K
D
R
K
A
L
V
T
G
G
D
S
G
I
G
R
A
A
A
I
A
Y
A
R
E
G
A
D
V
A
I
N
Y
L
P
A
E
E
E
D
A
Q
Q
V
K
A
L
I
E
E
C
G
R
K
A
V
L
L
P
G
D
L
S
D
E
S
F
A
R
S
L
V
H
K
A
R
E
A
L
------
G
G
L
D
I
L
A
L
V
A
G
--
K
Q
T
A
I
P
E
I
K
D
L
T
S
E
Q
-
F
Q
Q
T
F
A
V
N
V
F
A
L
F
W
I
T
Q
E
A
I
P
L
L
--
P
K
G
--
A
S
I
I
T
T
S
S
I
Q
A
Y
Q
P
S
P
H
L
L
D
Y
A
A
T
K
A
A
I
L
N
Y
S
R
G
L
A
K
Q
V
A
E
K
G
I
R
V
N
I
V
A
P
G
P
I
W
T
A
-----
L
Q
I
S
G
G
Q
T
Q
D
K
I
P
Q
-
F
G
Q
Q
T
P
M
K
R
A
G
Q
P
A
E
L
A
P
V
Y
V
Y
L
A
S
Q
E
S
S
Y
V
T
A
E
V
H
G
V
C
G
G
E
H
L
--
28
PsiBlast_CBE
67.05
44%
-53
- C1 -
3R3S
3
?
D:
[6-293]
-
D
P
T
T
Q
Y
Y
T
G
E
Y
P
K
Q
K
Q
P
A
P
G
V
Q
A
K
M
T
P
V
P
D
C
G
E
K
S
Y
V
G
S
G
R
L
K
D
R
K
A
L
V
T
G
G
D
S
G
I
G
R
A
A
A
I
A
Y
A
R
E
G
A
D
V
A
I
N
Y
L
P
A
E
E
E
D
A
Q
Q
V
K
A
L
I
E
E
C
G
R
K
A
V
L
L
P
G
D
L
S
D
E
S
F
A
R
S
L
V
H
K
A
R
E
A
L
------
G
G
L
D
I
L
A
L
V
A
G
--
K
Q
T
A
I
P
E
I
K
D
L
T
S
E
Q
-
F
Q
Q
T
F
A
V
N
V
F
A
L
F
W
I
T
Q
E
A
I
P
L
L
--
P
K
G
--
A
S
I
I
T
T
S
S
I
Q
A
Y
Q
P
S
P
H
L
L
D
Y
A
A
T
K
A
A
I
L
N
Y
S
R
G
L
A
K
Q
V
A
E
K
G
I
R
V
N
I
V
A
P
G
P
I
W
T
A
-----
L
Q
I
S
G
G
Q
T
Q
D
K
I
P
Q
-
F
G
Q
Q
T
P
M
K
R
A
G
Q
P
A
E
L
A
P
V
Y
V
Y
L
A
S
Q
E
S
S
Y
V
T
A
E
V
H
G
V
C
G
G
E
H
L
--
3
PsiBlast_PDB
66.92
44%
-54
- C1 -
3R3S
3
?
A:
[6-293]
-
D
P
T
T
Q
Y
Y
T
G
E
Y
P
K
Q
K
Q
P
A
P
G
V
Q
A
K
M
T
P
V
P
D
C
G
E
K
S
Y
V
G
S
G
R
L
K
D
R
K
A
L
V
T
G
G
D
S
G
I
G
R
A
A
A
I
A
Y
A
R
E
G
A
D
V
A
I
N
Y
L
P
A
E
E
E
D
A
Q
Q
V
K
A
L
I
E
E
C
G
R
K
A
V
L
L
P
G
D
L
S
D
E
S
F
A
R
S
L
V
H
K
A
R
E
A
L
------
G
G
L
D
I
L
A
L
V
A
G
--
K
Q
T
A
I
P
E
I
K
D
L
T
S
E
Q
-
F
Q
Q
T
F
A
V
N
V
F
A
L
F
W
I
T
Q
E
A
I
P
L
L
--
P
K
G
--
A
S
I
I
T
T
S
S
I
Q
A
Y
Q
P
S
P
H
L
L
D
Y
A
A
T
K
A
A
I
L
N
Y
S
R
G
L
A
K
Q
V
A
E
K
G
I
R
V
N
I
V
A
P
G
P
I
W
T
A
-----
L
Q
I
S
G
G
Q
T
Q
D
K
I
P
Q
-
F
G
Q
Q
T
P
M
K
R
A
G
Q
P
A
E
L
A
P
V
Y
V
Y
L
A
S
Q
E
S
S
Y
V
T
A
E
V
H
G
V
C
G
G
E
H
L
--
77
PsiBlast_CBE
64.97
34%
-101
- C1 -
3TZK
8
?
A:
[10-250]
------------------------------------------
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
-
I
G
T
A
T
-
S
E
S
G
A
Q
A
I
S
D
Y
L
-
G
D
N
G
K
G
M
A
L
--
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
------
G
G
V
D
I
L
V
N
N
A
A
--
I
T
R
-
D
N
L
L
M
R
M
K
E
E
E
-
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
--
M
K
K
R
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
-----
M
-
T
K
A
L
N
D
E
Q
R
T
A
T
-
L
A
-
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
S
P
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
--
94
PsiBlast_CBE
61.70
33%
-92
- C1 -
3RSH
11
FABG_VIBCH
A:
[10-250]
------------------------------------------
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
-
I
G
T
A
T
-
S
E
S
G
A
Q
A
I
S
D
Y
L
-
G
D
N
G
K
G
M
A
L
--
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
------
G
G
V
D
I
L
V
N
N
A
G
--
I
T
R
-
D
N
L
L
M
R
M
K
E
E
E
-
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
--
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
-----
M
-
T
K
---
D
E
Q
R
T
A
T
-
L
A
-
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
S
P
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
--
125
HHSearch
61.66
32%
-91
- C1 -
3ICC
5
?
A:
[3-254]
----------------------------------------
S
M
L
K
G
K
V
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
K
R
L
A
N
D
G
A
L
V
A
I
H
Y
G
N
-
R
K
E
E
A
E
E
T
V
Y
E
I
Q
S
N
G
G
S
A
F
S
I
G
A
N
L
E
S
L
H
G
V
E
A
L
Y
S
S
L
D
N
E
L
Q
N
R
TGS
T
K
F
D
I
L
I
N
N
A
G
--
I
G
P
G
A
-
F
I
E
E
T
T
E
Q
F
-
F
D
R
M
V
S
V
N
A
K
A
P
F
F
I
I
Q
Q
A
L
S
R
L
--
R
D
N
--
S
R
I
I
N
I
S
S
A
A
T
R
I
S
L
P
D
F
I
A
Y
S
M
T
K
G
A
I
N
T
M
T
F
T
L
A
K
Q
L
G
A
R
G
I
T
V
N
A
I
L
P
G
F
V
K
T
D
-----
M
-
N
A
E
L
L
S
D
P
M
M
K
Q
Y
A
T
T
I
S
A
F
N
R
L
G
E
V
E
D
I
A
D
T
A
A
F
L
A
S
P
D
S
R
W
V
T
G
Q
L
I
D
V
S
G
G
S
C
---
38
PsiBlast_CBE
61.47
36%
-94
- C1 -
4MOW
1
?
B:
[11-254]
-----------------------------------------
K
L
A
G
K
V
A
I
V
T
G
A
S
K
G
I
G
A
A
I
A
K
A
L
A
D
E
G
A
A
V
V
V
N
Y
A
S
-
S
K
A
G
A
D
A
V
V
S
A
I
T
E
A
G
G
R
A
V
A
V
G
G
D
V
S
K
A
A
D
A
Q
R
I
V
D
T
A
I
E
T
Y
------
G
R
L
D
V
L
V
N
N
S
G
V
Y
E
F
A
P
I
E
A
---
I
T
E
E
H
-
Y
R
R
Q
F
D
T
N
V
F
G
V
L
L
T
T
Q
A
A
V
K
H
L
--
G
E
G
--
A
S
I
I
N
I
S
S
V
V
T
S
I
T
P
P
A
S
A
V
Y
S
G
T
K
G
A
V
D
A
I
T
G
V
L
A
L
E
L
G
P
R
K
I
R
V
N
A
I
N
P
G
M
I
V
T
E
GTHSA---
G
S
D
L
E
A
Q
V
L
G
Q
-----
T
P
L
G
R
L
G
E
P
N
D
I
A
S
V
A
V
F
L
A
S
D
D
A
R
W
M
T
G
E
H
L
V
V
S
G
G
-----
76
PsiBlast_CBE
61.30
34%
-96
- C1 -
3TZK
7
?
B:
[10-250]
------------------------------------------
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
-
I
G
T
A
T
-
S
E
S
G
A
Q
A
I
S
D
Y
L
-
G
D
N
G
K
G
M
A
L
--
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
------
G
G
V
D
I
L
V
N
N
A
A
--
I
T
R
-
D
N
L
L
M
R
M
K
E
E
E
-
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
--
M
K
K
RQ
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
-----
M
-
T
K
A
L
N
D
E
Q
R
T
A
T
-
L
A
-
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
S
P
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
--
83
PsiBlast_CBE
61.09
33%
-95
- C1 -
3TZH
9
?
A:
[10-250]
------------------------------------------
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
-
I
G
T
A
T
-
S
E
S
G
A
Q
A
I
S
D
Y
L
-
G
D
N
G
K
G
M
A
L
--
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
------
G
G
V
D
I
L
V
N
N
A
G
--
I
T
R
-
D
N
L
L
M
R
M
K
E
E
E
-
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
--
M
K
K
R
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
A
I
E
T
D
-----
M
-
T
K
A
L
N
D
E
Q
R
T
A
T
-
L
A
-
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
S
P
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
--
96
PsiBlast_CBE
60.58
33%
-89
- C1 -
3RRO
11
FABG_VIBCH
A:
[10-250]
------------------------------------------
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
-
I
G
T
A
T
-
S
E
S
G
A
Q
A
I
S
D
Y
L
-
G
D
N
G
K
G
M
A
L
--
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
------
G
G
V
D
I
L
V
N
N
A
G
--
I
T
R
-
D
N
L
L
M
R
M
K
E
E
E
-
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
R
Q
--
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
-----
M
-
T
K
A
L
N
D
E
Q
R
T
A
T
-
L
A
-
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
S
P
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
--
78
PsiBlast_CBE
60.54
33%
-94
- C1 -
3TZH
14
?
F:
[10-250]
------------------------------------------
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
-
I
G
T
A
T
-
S
E
S
G
A
Q
A
I
S
D
Y
L
-
G
D
N
G
K
G
M
A
L
--
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
------
G
G
V
D
I
L
V
N
N
A
G
--
I
T
R
-
D
N
L
L
M
R
M
K
E
E
E
-
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
--
M
K
K
RQ
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
A
I
E
T
D
-----
M
-
T
K
A
L
N
D
E
Q
R
T
A
T
-
L
A
-
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
S
P
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
--
95
PsiBlast_CBE
58.74
33%
-92
- C1 -
3RRO
13
FABG_VIBCH
B:
[10-250]
------------------------------------------
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
-
I
G
T
A
T
-
S
E
S
G
A
Q
A
I
S
D
Y
L
-
G
D
N
G
K
G
M
A
L
--
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
------
G
G
V
D
I
L
V
N
N
A
G
--
I
T
R
-
D
N
L
L
M
R
M
K
E
E
E
-
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
MK
K
R
Q
--
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
-----
M
-
T
K
A
L
N
D
E
Q
R
T
A
T
-
L
A
-
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
S
P
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
--
6
PsiBlast_PDB
51.76
36%
-78
- C1 -
3OSU
15
FABG_STAAM
A:
[5-245]
---------------------------------------------
K
S
A
L
V
T
G
A
S
R
G
I
G
R
S
I
A
L
Q
L
A
E
E
G
Y
N
V
A
V
N
Y
A
G
-
S
K
E
K
A
E
A
V
V
E
E
I
K
A
K
G
V
D
S
F
A
I
Q
A
N
V
A
D
A
D
E
V
K
A
M
I
K
E
V
V
S
Q
F
------
G
S
L
D
V
L
V
N
N
A
G
----
I
T
R
D
N
L
L
M
R
M
K
E
Q
E
W
D
D
V
I
D
T
N
L
K
G
V
F
N
C
I
Q
K
A
T
P
Q
M
L
R
Q
R
S
--
G
A
I
I
N
L
S
S
V
V
G
A
V
G
N
P
G
Q
A
N
Y
V
A
T
K
A
G
V
I
G
L
T
K
S
A
A
R
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
F
I
V
S
D
-----
M
-
T
D
A
L
S
D
E
L
K
-
E
Q
-
M
L
T
Q
I
P
L
A
R
F
G
Q
D
T
D
I
A
N
T
V
A
F
L
A
S
D
K
A
K
Y
I
T
G
Q
T
I
H
V
N
G
G
M
Y
---