@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu09530: (2016-06-15 )
MEYTSIADTGIEASRIGLGTWAIGGTMWGGTDEKTSIETIRAALDQGITLIDTAPAYGFGQSEEIVGKAIKEYGKRDQVILATKTALDWKNNQLFRHANRARIVEEVENSLKRLQTDYIDLYQVHWPDPLVPIEETAEVMKELYDAGKIRAIGVSNFSIEQMDTFRAVAPLHTIQPPYNLFEREMEESVLPYAKDNKITTLLYGSLCRGLLTGKMTEEYTFEGDDLRNHDPKFQKPRFKEYLSAVNQLDKLAKTRYGKSVIHLAVRWILDQPGADIALWGARKPGQLEALSEITGWTLNSEDQKDINTILENTISDPVGPEFMAPPTREEI
Atome Classification :
(30 SA)
-.........10..--......20.-...-....30.........40....----....50.......-.-------60........70.-----.--.-...-..80........-----90.-----.......100.....-..110.......120.....-----.-----------------.130---------------..---------.......140.......150.......160.....------..-----170---..------..---...------..180.-.-..-..-.190........200.......210...----.-----------....220.......-230..--------.....--.240........250.-...-..---.260.......270.......280.....-.----.290...-.--.--..300.......310.......320.......330
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-MEYTSIADTGIE
A
--
S
RI
G
L
G
T
W
A
-IGG-TMWGG-TDEK
T
S
I
E
T
I
R
A
A
L
D----QG
I
T
L
I
DTAPAYG-F-------G
Q
S
E
E
I
V
G
K
A
I
K
E
-----Y--G-KRD-
Q
V
I
L
A
T
K
T
ALDW-----KN
N
-----
Q
L
F
R
H
A
N
R
A
R
I
V
E
E
V
-
E
N
S
L
K
R
L
Q
T
D
Y
I
D
L
Y
Q
V
HWP-----D-----------------PL-----------------V
P
---------
I
E
E
T
A
E
V
M
K
E
L
Y
DAG
K
I
R
A
I
GVSN
F
S
I
E
Q
M
D
T
F
R
A------VA-----P-----LH------TI---QP
P
------
Y
N
L
F
E
R
-
E
-
M
E
-
E
S-VLP-YAKDNK
I
T
T
L
L
Y
G
S
L
C
R
G
L
-
L
TGK----M-----------TE
E
Y
TFEGDDLRNH-DP-KF--------QK
P
R
F
--
K
E
-
Y
L
S
A
V
N
Q
L
D
K
L
A
K
-
T
RY-G
K
---
S
V
I
H
L
A
V
R
W
I
LDQPGA
D
I
A
L
WGARKPG
Q
L
-
E
----
A
L
S
E
IT
G
-
W
--T--LNS
E
D
Q
K
D
I
N
T
I
L
E
N
TISDPVGPEFMAPPTREEI
1
PsiBlast_PDB
94.77
97%
-97
- C5 -
1PZ1
1
GS69_BACSU
A:
[2-331]
--
E
Y
T
S
I
A
D
T
G
I
E
A
--
S
R
I
G
L
G
T
W
A
-
I
G
G
-
T
M
W
G
G
-
T
D
E
K
T
S
I
E
T
I
R
A
A
L
D
----
Q
G
I
T
L
I
D
T
A
P
A
Y
G
-
F
-------
G
Q
S
E
E
I
V
G
K
A
I
K
E
-----
Y
--
M
-
K
R
D
-
Q
V
I
L
A
T
K
T
A
L
D
W
-----
K
N
N
-----
Q
L
F
R
H
A
N
R
A
R
I
V
E
E
V
-
E
N
S
L
K
R
L
Q
T
D
Y
I
D
L
Y
Q
V
H
W
P
-----
D
-----------------
P
L
-----------------
V
P
---------
I
E
E
T
A
E
V
M
K
E
L
Y
D
A
G
K
I
R
A
I
G
V
S
N
F
S
I
E
Q
M
D
T
F
R
A
------
V
A
-----
P
-----
L
H
------
T
I
---
Q
P
P
------
Y
N
L
F
E
R
-
E
-
M
E
-
E
S
-
V
L
P
-
Y
A
K
D
N
K
I
T
T
L
L
Y
G
S
L
C
R
G
L
-
L
T
G
K
----
M
-----------
T
E
E
Y
T
F
E
G
D
D
L
R
N
H
-
D
P
-
K
F
--------
Q
K
P
R
F
--
K
E
-
Y
L
S
A
V
N
Q
L
D
K
L
A
K
-
T
R
Y
-
G
K
---
S
V
I
H
L
A
V
R
W
I
L
D
Q
P
G
A
D
I
A
L
W
G
A
R
K
P
G
Q
L
-
E
----
A
L
S
E
I
T
G
-
W
--
T
--
L
N
S
E
D
Q
K
D
I
N
T
I
L
E
N
T
I
S
D
P
V
G
P
E
F
M
A
P
P
T
R
E
E
I
49
HHSearch
94.25
98%
-99
- C5 -
1PZ1
1
GS69_BACSU
A:
[1-331]
-
M
E
Y
T
S
I
A
D
T
G
I
E
A
--
S
R
I
G
L
G
T
W
A
-
I
G
G
-
T
M
W
-
G
G
T
D
E
K
T
S
I
E
T
I
R
A
A
L
D
----
Q
G
I
T
L
I
D
T
A
P
A
Y
G
-
F
-------
G
Q
S
E
E
I
V
G
K
A
I
K
E
-----
Y
--
M
-
K
R
D
-
Q
V
I
L
A
T
K
T
A
L
D
W
-----
K
N
N
-----
Q
L
F
R
H
A
N
R
A
R
I
V
E
E
V
-
E
N
S
L
K
R
L
Q
T
D
Y
I
D
L
Y
Q
V
H
W
P
-----
D
-----------------
P
L
-----------------
V
P
---------
I
E
E
T
A
E
V
M
K
E
L
Y
D
A
G
K
I
R
A
I
G
V
S
N
F
S
I
E
Q
M
D
T
F
R
A
------
V
A
-----
P
-----
L
H
------
T
I
---
Q
P
P
------
Y
N
L
F
E
R
-
E
-
M
E
-
E
S
-
V
L
P
-
Y
A
K
D
N
K
I
T
T
L
L
Y
G
S
L
C
R
G
L
-
L
T
G
K
----
M
-----------
T
E
E
Y
T
F
E
G
D
D
L
R
N
H
-
D
P
-
K
F
--------
Q
K
P
-
R
--
F
K
E
Y
L
S
A
V
N
Q
L
D
K
L
A
K
T
R
Y
--
G
K
---
S
V
I
H
L
A
V
R
W
I
L
D
Q
P
G
A
D
I
A
L
W
G
A
R
K
P
G
Q
L
-
E
----
A
L
S
E
I
T
G
-
W
--
T
--
L
N
S
E
D
Q
K
D
I
N
T
I
L
E
N
T
I
S
D
P
V
G
P
E
F
M
A
P
P
T
R
E
E
I
50
HHSearch
83.41
56%
-107
- C5 -
3N2T
-
?
A:
[3-327]
-
S
D
T
I
R
I
P
G
I
D
T
P
L
--
S
R
V
A
L
G
T
W
A
-
I
G
G
-
W
M
W
-
G
G
P
D
D
D
N
G
V
R
T
I
H
A
A
L
D
----
E
G
I
N
L
I
D
T
A
P
V
Y
G
-
F
-------
G
H
S
E
E
I
V
G
R
A
L
A
E
----------
K
P
N
-
K
A
H
V
A
T
K
L
G
L
H
W
-----
V
G
E
DEKN
M
K
V
F
R
D
S
R
P
A
R
I
R
K
E
V
-
E
D
S
L
R
R
L
R
V
E
T
I
D
L
E
Q
I
H
W
P
-----
D
-----------------
D
K
-----------------
T
P
---------
I
D
E
S
A
R
E
L
Q
K
L
H
Q
D
G
K
I
R
A
L
G
V
S
N
F
S
P
E
Q
M
D
I
F
R
E
------
V
A
-----
P
-----
L
A
------
T
I
---
Q
P
P
------
L
N
L
F
E
R
-
T
-
I
E
-
K
D
-
I
L
P
-
Y
A
E
K
H
N
A
V
V
L
A
Y
G
A
L
C
R
G
L
-
L
T
G
K
----
M
-----------
N
R
D
T
T
F
P
K
D
D
L
R
S
N
-
D
P
-
K
F
--------
Q
K
P
-
N
--
F
E
K
Y
L
A
A
M
D
E
F
E
K
L
A
E
-
K
R
--
G
K
---
S
V
M
A
F
A
V
R
W
V
L
D
Q
G
P
V
-
I
A
L
W
G
A
R
K
P
G
Q
V
-
S
----
G
V
K
D
V
F
G
-
W
--
S
--
L
T
D
E
E
K
K
A
V
D
D
I
L
A
R
H
V
P
N
P
I
D
P
T
F
M
A
-------
2
PsiBlast_PDB
83.08
55%
-105
- C5 -
3N2T
-
?
A:
[1-327]
-
M
A
S
D
T
I
R
I
P
G
I
D
T
P
L
S
R
V
A
L
G
T
W
A
-
I
G
G
-
W
M
W
G
G
-
P
D
D
D
N
G
V
R
T
I
H
A
A
L
D
----
E
G
I
N
L
I
D
T
A
P
V
Y
G
-
F
-------
G
H
S
E
E
I
V
G
R
A
L
A
E
----------
K
P
N
-
K
A
H
V
A
T
K
L
G
L
H
W
V
G
EDE
K
N
M
-----
K
V
F
R
D
S
R
P
A
R
I
R
K
E
V
-
E
D
S
L
R
R
L
R
V
E
T
I
D
L
E
Q
I
H
W
P
-----
D
-----------------
D
K
-----------------
T
P
---------
I
D
E
S
A
R
E
L
Q
K
L
H
Q
D
G
K
I
R
A
L
G
V
S
N
F
S
P
E
Q
M
D
I
F
R
E
------
V
A
-----
P
-----
L
A
------
T
I
---
Q
P
P
------
L
N
L
F
E
R
-
T
-
I
E
-
K
D
-
I
L
P
-
Y
A
E
K
H
N
A
V
V
L
A
Y
G
A
L
C
R
G
L
-
L
T
G
K
----
M
-----------
N
R
D
T
T
F
P
K
D
D
L
R
S
N
-
D
P
-
K
F
--------
Q
K
P
N
F
--
E
K
-
Y
L
A
A
M
D
E
F
E
K
L
A
E
-
K
R
--
G
K
---
S
V
M
A
F
A
V
R
W
V
L
D
Q
-
G
P
V
I
A
L
W
G
A
R
K
P
G
Q
V
-
S
----
G
V
K
D
V
F
G
-
W
--
S
--
L
T
D
E
E
K
K
A
V
D
D
I
L
A
R
H
V
P
N
P
I
D
P
T
F
M
A
-------
3
PsiBlast_PDB
74.18
37%
-105
- C5 -
1PYF
3
IOLS_BACSU
A:
[6-309]
------
L
G
K
S
D
L
Q
V
--
F
P
I
G
L
G
T
N
A
-
V
G
G
H
N
L
Y
P
N
-
L
N
E
E
T
G
K
E
L
V
R
E
A
I
R
----
N
G
V
T
M
L
D
T
A
Y
I
Y
G
-
I
-------
G
R
S
E
E
L
I
G
E
V
L
R
E
-----
F
--
N
-
R
E
D
--
V
V
I
A
T
K
A
A
H
R
K
-----
Q
G
N
-----
D
F
V
F
D
N
S
P
D
F
L
K
K
S
V
-
D
E
S
L
K
R
L
N
T
D
Y
I
D
L
F
Y
I
H
F
P
-----
D
-----------------
E
H
-----------------
T
P
---------
K
D
E
A
V
N
A
L
N
E
M
K
K
A
G
K
I
R
S
I
G
V
S
N
F
S
L
E
Q
L
K
E
A
N
K
------
D
G
-----
L
-----
V
D
------
V
L
---
Q
G
E
------
Y
N
L
L
N
R
-
E
-
A
E
-
K
T
-
F
F
P
-
Y
T
K
E
H
N
I
S
F
I
P
Y
F
P
L
V
S
G
L
-
L
A
G
K
----
Y
-----------
T
E
D
T
T
F
P
E
G
D
L
R
N
E
-
Q
E
-
H
F
--------
K
G
E
R
F
--
K
E
-
N
I
R
K
V
N
K
L
A
P
I
A
E
--
K
H
-
N
V
---
D
I
P
H
I
V
L
A
W
Y
L
A
R
P
E
I
D
I
L
I
P
G
A
K
R
A
D
Q
L
-
I
----
D
N
I
K
T
A
D
-
V
--
T
--
L
S
Q
E
D
I
S
F
I
D
K
L
F
---------------------
4
PsiBlast_PDB
73.86
37%
-105
- C5 -
1PZ0
2
IOLS_BACSU
A:
[6-309]
------
L
G
K
S
D
L
Q
V
--
F
P
I
G
L
G
T
N
A
-
V
G
G
H
N
L
Y
P
N
-
L
N
E
E
T
G
K
E
L
V
R
E
A
I
R
----
N
G
V
T
M
L
D
T
A
Y
I
Y
G
-
I
-------
G
R
S
E
E
L
I
G
E
V
L
R
E
-----
F
--
N
-
R
E
D
--
V
V
I
A
T
K
A
A
H
R
K
-----
Q
G
N
-----
D
F
V
F
D
N
S
P
D
F
L
K
K
S
V
-
D
E
S
L
K
R
L
N
T
D
Y
I
D
L
F
Y
I
H
F
P
-----
D
-----------------
E
H
-----------------
T
P
---------
K
D
E
A
V
N
A
L
N
E
M
K
K
A
G
K
I
R
S
I
G
V
S
N
F
S
L
E
Q
L
K
E
A
N
K
------
D
G
-----
L
-----
V
D
------
V
L
---
Q
G
E
------
Y
N
L
L
N
R
-
E
-
A
E
-
K
T
-
F
F
P
-
Y
T
K
E
H
N
I
S
F
I
P
Y
F
P
L
V
S
G
L
-
L
A
G
K
----
Y
-----------
T
E
D
T
T
F
P
E
G
D
L
R
N
E
-
Q
E
-
H
F
--------
K
G
E
R
F
--
K
E
-
N
I
R
K
V
N
K
L
A
P
I
A
E
--
K
H
-
N
V
---
D
I
P
H
I
V
L
A
W
Y
L
A
R
P
E
I
D
I
L
I
P
G
A
K
R
A
D
Q
L
-
I
----
D
N
I
K
T
A
D
-
V
--
T
--
L
S
Q
E
D
I
S
F
I
D
K
L
F
---------------------
52
HHSearch
72.41
36%
-98
- C5 -
1PYF
3
IOLS_BACSU
A:
[2-311]
--
K
K
A
K
L
G
K
S
D
L
Q
V
--
F
P
I
G
L
G
T
N
A
-
V
G
G
-
H
N
L
Y
P
N
L
N
E
E
T
G
K
E
L
V
R
E
A
I
R
----
N
G
V
T
M
L
D
T
A
Y
I
Y
G
-
I
-------
G
R
S
E
E
L
I
G
E
V
L
R
E
--------
F
-
N
R
E
-
D
V
V
I
A
T
K
A
A
H
R
K
-----
Q
G
N
-----
D
F
V
F
D
N
S
P
D
F
L
K
K
S
V
-
D
E
S
L
K
R
L
N
T
D
Y
I
D
L
F
Y
I
H
F
P
-----
D
-----------------
E
H
-----------------
T
P
---------
K
D
E
A
V
N
A
L
N
E
M
K
K
A
G
K
I
R
S
I
G
V
S
N
F
S
L
E
Q
L
K
E
A
N
K
------
D
G
-----
L
-----
V
D
------
V
L
---
Q
G
E
------
Y
N
L
L
N
R
-
E
-
A
E
-
K
T
-
F
F
P
-
Y
T
K
E
H
N
I
S
F
I
P
Y
F
P
L
V
S
G
L
-
L
A
G
K
----
Y
-----------
T
E
D
T
T
F
P
E
G
D
L
R
N
E
-
Q
E
-
H
F
--------
K
G
E
-
R
--
F
K
E
N
I
R
K
V
N
K
L
A
P
I
A
E
-
K
H
--
N
V
---
D
I
P
H
I
V
L
A
W
Y
L
A
R
P
E
I
D
I
L
I
P
G
A
K
R
A
D
Q
L
-
I
----
D
N
I
K
T
A
D
-
V
--
T
--
L
S
Q
E
D
I
S
F
I
D
K
L
F
A
P
-------------------
54
HHSearch
70.81
32%
-94
- C5 -
1LQA
1
TAS_ECOLI
A:
[1-342]
-
M
Q
Y
H
R
I
P
H
S
S
L
E
V
--
S
T
L
G
L
G
T
M
T
-
F
G
E
-
Q
-----
N
S
E
A
D
A
H
A
Q
L
D
Y
A
V
A
----
Q
G
I
N
L
I
D
V
A
E
M
Y
P
-
V
PPRPETQ
G
L
T
E
T
Y
V
G
N
W
L
A
K
-----
H
--
G
-
S
R
E
-
K
L
I
I
A
S
K
V
S
G
P
S
-----
R
N
N
DKGI-
R
P
D
Q
A
L
D
R
K
N
I
R
E
A
L
-
H
D
S
L
K
R
L
Q
T
D
Y
L
D
L
Y
Q
V
H
W
P
-----
Q
-----------------
R
P
TNCFGKL
G
Y
S
W
T
DSAPA
V
S
---------
L
L
D
T
L
D
A
L
A
E
Y
Q
R
A
G
K
I
R
Y
I
G
V
S
N
E
T
A
F
G
V
M
R
Y
L
H
L
A
D
K
H
D
L
P
-----
R
-----
I
V
------
T
I
---
Q
N
P
------
Y
S
L
L
N
R
-
S
-
F
E
-
V
G
-
L
A
E
-
V
S
Q
Y
E
G
V
E
L
L
A
Y
S
C
L
G
F
G
T
-
L
T
G
K
----
Y
-----------
L
N
G
A
K
-
P
A
G
-
A
R
N
T
-
L
F
S
R
F
--------
T
R
-
Y
S
--
G
E
Q
T
Q
K
A
V
A
A
Y
V
D
I
A
R
-
R
H
--
G
L
---
D
P
A
Q
M
A
L
A
F
V
R
R
Q
P
F
V
A
S
T
L
L
G
A
T
T
M
D
Q
L
-
K
----
T
N
I
E
S
L
H
-
L
--
E
--
L
S
E
D
V
L
A
E
I
E
A
V
H
Q
V
Y
T
-----------------
55
HHSearch
70.76
28%
-121
- C5 -
1YNP
13
?
A:
[21-311]
-
M
K
K
R
Q
L
G
T
S
D
L
H
V
--
S
E
L
G
F
G
C
M
S
-
L
G
T
--------
D
E
T
K
A
R
R
I
M
D
E
V
L
E
----
L
G
I
N
Y
L
D
T
A
D
L
Y
N
-
Q
-------
G
L
N
E
Q
F
V
G
K
A
L
K
G
----------
R
R
Q
-
D
I
I
L
A
T
K
V
-----------------------
S
K
A
Y
I
K
E
A
V
-
K
D
S
L
R
R
L
Q
T
D
Y
I
D
L
Y
Q
L
H
G
G
-----
T
-----------------
I
D
-----------------
D
P
---------
I
D
E
T
I
E
A
F
E
E
L
K
Q
E
G
V
I
R
Y
Y
G
I
S
S
I
R
P
N
V
I
K
E
Y
L
K
------
R
S
-----
N
-----
I
V
------
S
I
---
M
M
Q
------
Y
S
I
L
D
R
-
R
-
P
E
--
E
-
W
F
P
-
L
I
Q
E
H
G
V
S
V
V
V
R
G
P
V
A
R
G
L
-
L
S
R
R
----
P
-----------
L
P
E
G
E
-----
G
Y
--------------------------
L
N
Y
R
Y
D
E
L
K
L
L
R
E
-
S
L
P
T
D
R
---
P
L
H
E
L
A
L
Q
Y
C
L
A
H
D
V
V
A
T
V
A
A
G
A
S
S
I
D
Q
V
-
K
----
A
N
V
Q
A
V
E
A
T
--
P
--
L
T
A
E
E
R
Q
H
I
Q
K
L
A
K
A
A
V
-----------------
57
HHSearch
69.22
28%
-107
- C5 -
3N6Q
1
GPR_ECOLI
A:
[13-335]
-
M
Q
Y
R
Y
C
G
K
S
G
L
R
L
--
P
A
L
S
L
G
L
W
H
-
N
F
G
-
H
-
V
---
N
A
L
E
S
Q
R
A
I
L
R
K
A
F
D
----
L
G
I
T
H
F
D
L
A
N
N
Y
G
-
P
PP-----
G
S
A
E
E
N
F
G
R
L
L
R
E
-----
D
FA
A
-
Y
R
D
-
E
L
I
I
S
T
K
A
G
Y
D
M
-----
W
P
G
-----
P
Y
G
S
G
G
S
R
K
Y
L
L
A
S
L
-
D
Q
S
L
K
R
M
G
L
E
Y
V
D
I
F
Y
S
H
R
V
-----
D
-----------------
E
N
-----------------
T
P
---------
M
E
E
T
A
S
A
L
A
H
A
V
Q
S
G
K
A
L
Y
V
G
I
S
S
Y
S
P
E
R
T
Q
K
M
V
E
L
L
R
E
W
-
K
I
-----
P
-----
L
L
------
I
H
---
Q
P
S
------
Y
N
L
L
N
R
-
W
-
V
D
K
S
G
-
L
L
D
-
T
L
Q
N
N
G
V
G
C
I
A
F
T
P
L
A
Q
G
L
-
L
T
G
K
----
Y
-----------
L
-------------------------------
L
--
T
E
A
N
L
N
S
L
R
L
L
N
E
M
A
Q
-
Q
R
--
G
Q
---
S
M
A
Q
M
A
L
S
W
L
L
K
D
D
R
V
T
S
V
L
I
G
A
S
R
A
E
Q
L
-
E
----
E
N
V
Q
A
L
N
N
L
--
T
--
F
S
T
K
E
L
A
Q
I
D
Q
H
I
A
D
G
------------------
16
PsiBlast_PDB
68.07
28%
-104
- C5 -
1ZSX
4
KCAB2_HUMAN
A:
[26-344]
---
Y
R
N
L
G
K
S
G
L
R
V
--
S
C
L
G
L
G
T
W
V
-----
T
F
G
G
Q
-
I
T
D
E
M
A
E
Q
L
M
T
L
A
Y
D
----
N
G
I
N
L
F
D
T
A
E
V
Y
A
-
A
-------
G
K
A
E
V
V
L
G
N
I
I
K
K
-----
K
--
G
W
R
R
S
-
S
L
V
I
T
T
K
I
F
W
G
G
-----
K
A
------
E
T
E
R
G
L
S
R
K
H
I
I
E
G
L
-
K
A
S
L
E
R
L
Q
L
E
Y
V
D
V
V
F
A
N
R
P
-----
D
-----------------
P
N
-----------------
T
P
---------
M
E
E
T
V
R
A
M
T
H
V
I
N
Q
G
M
A
M
Y
W
G
T
S
R
W
S
S
M
E
I
M
E
A
Y
S
------
V
A
-----
R
-----
Q
F
------
N
L
---
T
P
P
ICEQ
A
E
Y
H
M
F
Q
R
-
E
-
K
V
-
E
V
-
Q
L
P
E
L
F
H
K
I
G
V
G
A
M
T
W
S
P
L
A
C
G
I
-
V
S
G
K
----
Y
DSGIPPYSRAS
L
K
G
Y
Q
W
L
K
D
K
I
L
S
E
-
E
G
-
R
R
--------
Q
Q
A
K
L
--
K
E
--
L
Q
A
I
A
E
--------
R
L
-
G
C
---
T
L
P
Q
L
A
I
A
W
C
L
R
N
E
G
V
S
S
V
L
L
G
A
S
N
A
D
Q
L
M
E
----
N
I
G
A
I
Q
V
-
L
P-
K
--
L
S
S
S
I
I
H
E
I
D
S
I
L
G
N
-------------------
7
PsiBlast_PDB
67.84
29%
-116
- C5 -
3UYI
-
PERR_RAUSE
A:
[1-306]
-
M
P
R
V
K
L
G
T
Q
G
L
E
V
--
S
K
L
G
F
G
C
M
G
-
L
S
G
-------
L
P
E
E
Q
G
I
A
V
I
K
E
A
F
N
----
C
G
I
T
F
F
D
T
S
D
I
Y
G
E
N
-------
G
S
N
E
E
L
L
G
K
A
L
K
Q
-----
L
----
P
R
E
-
K
I
Q
V
G
T
K
F
G
I
H
E
-----
I
G
F
-----
S
G
V
K
A
K
G
T
P
D
Y
V
R
S
C
C
E
A
S
L
K
R
L
D
V
D
Y
I
D
L
F
Y
I
H
R
I
-----
D
-----------------
T
T
-----------------
V
P
---------
I
E
I
T
M
G
E
L
-
K
L
V
E
E
G
K
I
K
Y
V
G
L
S
E
A
S
P
D
T
I
R
R
A
H
A
------
V
H
-----
P
-----
V
T
------
A
L
---
Q
I
E
------
Y
S
L
W
T
R
-
D
-
I
E
-
D
E
-
I
V
P
-
L
C
R
Q
L
G
I
G
I
V
P
Y
S
P
I
G
R
G
L
-
F
A
G
K
----
A
-----------
I
K
E
S
--------------------------------
K
-
N
K
Q
I
Y
Y
R
I
E
A
L
S
Q
--
K
H
-
G
C
---
T
P
V
Q
L
A
L
A
W
V
L
H
Q
G
E
D
V
V
P
I
P
G
T
T
K
I
K
N
L
-
H
----
N
N
V
G
A
L
K
-
V
--
K
--
L
T
K
E
D
L
K
E
I
S
------------------------
72
Fugue
67.65
26%
-95
- C5 -
1QRQ
1
KCAB2_RAT
A:
[1-325]
L
Q
F
Y
R
N
L
G
K
S
G
L
R
V
--
S
C
L
G
L
G
T
W
V
-
T
F
G
----
G
Q
-
I
T
D
E
M
A
E
H
L
M
T
L
A
Y
D
----
N
G
I
N
L
F
D
T
A
E
V
Y
A
-
A
-------
G
K
A
E
V
V
L
G
N
I
I
K
K
-----
K
G-
W
-
R
R
S
-
S
L
V
I
T
T
K
I
F
W
G
G
-----
K
A
E
-----
T
E
R
G
L
-
S
R
K
H
I
I
E
G
L
-
K
A
S
L
E
R
L
Q
L
E
Y
V
D
V
V
F
A
N
R
P
-----
D
-----------------
P
-N----------------
T
P
---------
M
E
E
T
V
R
A
M
T
H
V
I
N
Q
G
M
A
M
Y
W
G
T
S
R
W
S
S
M
E
I
M
E
A
Y
S
------
V
A
-----
R
-----
Q
F
NLIPPI
C
E
---
Q
A
E
------
Y
H
M
F
Q
R
E
K
-
V
E
-
V
Q
-
L
P
E
-
L
F
H
K
I
G
V
G
A
M
T
W
S
P
L
A
C
G
I
-
V
S
G
K
YDSG
I
-----------
P
P
Y
S
R
A
S
L
K
G
Y
Q
W
L
-
K
D
-
K
I
--------
L
S
E
E
G
--
R
R
-
Q
Q
A
K
L
K
E
L
Q
A
I
A
E
-
R
L
--
G
C
---
T
L
P
Q
L
A
I
A
W
C
L
R
N
E
G
V
S
S
V
L
L
G
A
S
N
A
E
Q
L
-
M
----
E
N
I
G
A
I
Q
-
V
LP
K
--
L
S
S
S
I
V
H
E
I
D
S
I
L
G
N
K
P
Y
----------------
59
HHSearch
66.93
28%
-106
- C5 -
3ERP
17
?
A:
[34-351]
-
M
E
Y
R
R
C
G
R
S
G
V
K
L
--
P
A
I
S
L
G
L
W
H
-
N
F
G
-
D
---
T
-
T
R
V
E
N
S
R
A
L
L
Q
R
A
F
D
----
L
G
I
T
H
F
D
L
A
N
N
Y
G
-
P
PP-----
G
S
A
E
C
N
F
G
R
I
L
Q
E
-----
D
FL
P
-
W
R
D
-
E
L
I
I
S
T
K
A
G
Y
T
M
-----
W
D
G
-----
P
Y
G
D
W
G
S
R
K
Y
L
I
A
S
L
-
D
Q
S
L
K
R
M
G
L
E
Y
V
D
I
F
Y
H
H
R
P
-----
D
-----------------
P
E
-----------------
T
P
---------
L
K
E
T
M
K
A
L
D
H
L
V
R
H
G
K
A
L
Y
V
G
I
S
N
Y
P
A
D
L
A
R
Q
A
I
D
I
L
E
D
L
-
G
T
-----
P
-----
C
L
------
I
H
---
Q
P
K
------
Y
S
L
F
E
R
-
W
-
V
E
-
D
G
-
L
L
A
-
L
L
Q
E
K
G
V
G
S
I
A
F
S
P
L
A
G
G
Q
-
L
T
D
R
----
Y
-----------
L
N
------------------------------
I
--
T
A
D
K
L
E
K
V
R
R
L
N
E
L
A
A
-
R
R
--
G
Q
---
K
L
S
Q
M
A
L
A
W
V
L
R
N
D
N
V
T
S
V
L
I
G
A
S
K
P
S
Q
I
-
E
----
D
A
V
G
M
L
A
N
R
--
R
--
F
S
A
A
E
C
A
E
I
D
A
I
L
E
G
-------------------
71
Fugue
66.85
27%
-98
- C5 -
1QRQ
1
KCAB2_RAT
A:
[1-325]
L
Q
F
Y
R
N
L
G
K
S
G
L
R
V
--
S
C
L
G
L
G
T
W
----
V
-
T
F
G
G
Q
-
I
T
D
E
M
A
E
H
L
M
T
L
A
Y
D
----
N
G
I
N
L
F
D
T
A
E
V
Y
A
-
A
-------
G
K
A
E
V
V
L
G
N
I
I
K
K
-----
K
--
G
W
R
R
S
-
S
L
V
I
T
T
K
I
F
W
G
G
-----
K
A
E
-----
T
E
-
R
G
L
S
R
K
H
I
I
E
G
L
-
K
A
S
L
E
R
L
Q
L
E
Y
V
D
V
V
F
A
N
R
P
-----
D
-----------------
P
N
-----------------
T
P
---------
M
E
E
T
V
R
A
M
T
H
V
I
N
Q
G
M
A
M
Y
W
G
T
S
R
W
S
S
M
E
I
M
E
A
Y
S
------
V
A
-----
R
-----
Q
F
NLIPPI
C
E
---
Q
A
E
------
Y
H
M
F
Q
R
-
E
K
V
E
-
V
Q
-
L
P
E
-
L
F
H
K
I
G
V
G
A
M
T
W
S
P
L
A
C
G
I
-
V
S
G
K
YDSG
I
-----------
P
P
Y
S
R
A
S
L
K
G
Y
Q
W
L
-
K
D
-
K
I
--------
L
S
E
E
G
--
R
R
-
Q
Q
A
K
L
K
E
L
Q
A
I
A
E
-
R
L
--
G
C
---
T
L
P
Q
L
A
I
A
W
C
L
R
N
E
G
V
S
S
V
L
L
G
A
S
N
A
E
Q
L
-
M
----
E
N
I
G
A
I
Q
-
V
--
L
PK
L
S
S
S
I
V
H
E
I
D
S
I
L
G
N
K
P
Y
----------------
14
PsiBlast_PDB
66.85
28%
-108
- C5 -
3N6Q
1
GPR_ECOLI
A:
[13-319]
-
M
Q
Y
R
Y
C
G
K
S
G
L
R
L
--
P
A
L
S
L
G
L
W
H
-
N
F
G
-
H
V
-
N
A
-
L
E
S
Q
R
A
I
--
L
R
K
A
F
D
----
L
G
I
T
H
F
D
L
A
N
N
Y
G
-
P
PP-----
G
S
A
E
E
N
F
G
R
L
L
R
E
DF---
A
--
A
-
Y
R
D
-
E
L
I
I
S
T
K
A
G
Y
D
M
-----
W
P
G
-----
P
Y
G
S
G
G
S
R
K
Y
L
L
A
S
L
-
D
Q
S
L
K
R
M
G
L
E
Y
V
D
I
F
Y
S
H
R
V
-----
D
-----------------
E
N
-----------------
T
P
---------
M
E
E
T
A
S
A
L
A
H
A
V
Q
S
G
K
A
L
Y
V
G
I
S
S
Y
S
P
E
R
T
Q
K
M
V
E
------
L
L
R
E
W
KI
P
-----
L
L
------
I
H
---
Q
P
S
------
Y
N
L
L
N
R
-
W
-
V
D
-
K
S
G
L
L
D
-
T
L
Q
N
N
G
V
G
C
I
A
F
T
P
L
A
Q
G
L
-
L
T
G
K
----
Y
-----------
L
---------------------------
L
T
-----
E
A
-
N
L
N
S
L
R
L
L
N
E
M
A
Q
-
Q
R
--
G
Q
---
S
M
A
Q
M
A
L
S
W
L
L
K
D
D
R
V
T
S
V
L
I
G
A
S
R
A
E
Q
L
-
E
E
N
V
Q
A
L
N
N
L
T
------------------------------------------
20
PsiBlast_PDB
66.76
29%
-101
- C5 -
1QRQ
1
KCAB2_RAT
A:
[4-322]
---
Y
R
N
L
G
K
S
G
L
R
V
--
S
C
L
G
L
G
T
W
V
T
F
G
G
-
Q
I
----
T
D
E
M
A
E
-
H
L
M
T
L
A
Y
D
----
N
G
I
N
L
F
D
T
A
E
V
Y
A
-
A
-------
G
K
A
E
V
V
L
G
N
I
I
K
K
-----
K
--
G
W
R
R
S
-
S
L
V
I
T
T
K
I
F
W
G
G
-----
K
A
------
E
T
E
R
G
L
S
R
K
H
I
I
E
G
L
-
K
A
S
L
E
R
L
Q
L
E
Y
V
D
V
V
F
A
N
R
P
-----
D
-----------------
P
N
-----------------
T
P
---------
M
E
E
T
V
R
A
M
T
H
V
I
N
Q
G
M
A
M
Y
W
G
T
S
R
W
S
S
M
E
I
M
E
A
Y
S
------
V
A
-----
R
-----
Q
F
------
N
L
---
I
P
P
I
C
E
Q
A
E
Y
H
M
F
Q
R
-
E
-
K
V
-
E
V
-
Q
L
P
E
L
F
H
K
I
G
V
G
A
M
T
W
S
P
L
A
C
G
I
-
V
S
G
K
----
Y
DSG
I
P
P
Y
S
RAS
L
K
G
Y
Q
W
L
K
D
K
I
L
S
E
-
E
G
-
R
R
--------
Q
Q
A
K
L
--
K
E
--
L
Q
A
I
A
E
--------
R
L
-
G
C
---
T
L
P
Q
L
A
I
A
W
C
L
R
N
E
G
V
S
S
V
L
L
G
A
S
N
A
E
Q
L
M
E
----
N
I
G
A
I
Q
V
-
L
P-
K
--
L
S
S
S
I
V
H
E
I
D
S
I
L
G
N
-------------------
64
HHSearch
66.57
31%
-117
- C5 -
4WGH
2
?
A:
[25-301]
-
K
K
T
V
R
F
G
E
-
Q
A
A
V
--
P
A
I
G
L
G
T
W
Y
-
M
G
E
-
H
-
A
---
A
Q
R
Q
Q
E
V
A
A
L
R
A
G
I
D
----
H
G
L
T
V
I
D
T
A
E
M
Y
A
-
D
-------
G
G
A
E
E
V
V
G
Q
A
I
R
G
----------
L
R
D
-
R
V
V
L
V
S
K
V
Y
P
W
H
------------------
A
G
K
A
A
M
H
R
A
C
-
E
N
S
L
R
R
L
Q
T
D
Y
L
D
M
Y
L
L
H
W
R
-----
G
-----------------
D
I
------------------
P
---------
L
Q
E
T
V
E
A
M
E
K
L
V
A
E
G
K
I
R
R
W
G
V
S
N
L
D
T
E
D
M
Q
A
L
W
R
TAD---
G
E
-----
H
-----
C
A
------
T
N
---
Q
V
L
------
Y
H
L
A
S
R
-
G
-
I
E
-
Y
D
-
L
L
P
-
W
C
Q
Q
H
S
L
P
V
M
A
Y
C
P
L
A
Q
A
G
R
L
R
D
G
----
L
-----------
F
----------------------------------------
Q
H
S
D
I
I
N
M
A
N
-
A
R
--
G
I
---
T
V
A
Q
L
L
L
A
W
V
I
R
H
P
G
V
L
-
A
I
P
K
A
A
S
I
E
H
V
-
V
----
Q
N
A
A
A
L
D
-
I
--
V
--
L
S
G
E
E
L
A
Q
L
D
R
L
Y
P
P
P
Q
R
K
N
--------------
18
PsiBlast_PDB
66.22
28%
-105
- C5 -
3EAU
3
KCAB2_RAT
A:
[5-323]
---
Y
R
N
L
G
K
S
G
L
R
V
--
S
C
L
G
L
G
T
W
V
-
T
F
G
----
G
Q
-
I
T
D
E
M
A
E
H
L
M
T
L
A
Y
D
----
N
G
I
N
L
F
D
T
A
E
V
Y
A
-
A
-------
G
K
A
E
V
V
L
G
N
I
I
K
K
-----
K
--
G
W
R
R
S
-
S
L
V
I
T
T
K
I
F
W
G
G
-----
K
A
------
E
T
E
R
G
L
S
R
K
H
I
I
E
G
L
-
K
A
S
L
E
R
L
Q
L
E
Y
V
D
V
V
F
A
N
R
P
-----
D
-----------------
P
N
-----------------
T
P
---------
M
E
E
T
V
R
A
M
T
H
V
I
N
Q
G
M
A
M
Y
W
G
T
S
R
W
S
S
M
E
I
M
E
A
Y
S
------
V
A
-----
R
-----
Q
F
------
N
L
---
I
P
P
ICEQ
A
E
Y
H
M
F
Q
R
-
E
-
K
V
-
E
V
-
Q
L
P
E
L
F
H
K
I
G
V
G
A
M
T
W
S
P
L
A
C
G
I
-
V
S
G
K
----
Y
DSGIPPYSRAS
L
K
G
Y
Q
W
L
K
D
K
I
L
S
E
-
E
G
-
R
R
--------
Q
Q
A
K
L
--
K
E
--
L
Q
A
I
A
E
--------
R
L
-
G
C
---
T
L
P
Q
L
A
I
A
W
C
L
R
N
E
G
V
S
S
V
L
L
G
A
S
N
A
E
Q
L
M
E
----
N
I
G
A
I
Q
V
-
L
P-
K
--
L
S
S
S
I
V
H
E
I
D
S
I
L
G
N
-------------------
19
PsiBlast_PDB
66.03
28%
-103
- C5 -
3EB4
2
KCAB2_RAT
A:
[5-323]
---
Y
R
N
L
G
K
S
G
L
R
V
--
S
C
L
G
L
G
T
W
V
-
T
F
G
----
G
Q
-
I
T
D
E
M
A
E
H
L
M
T
L
A
Y
D
----
N
G
I
N
L
F
D
T
A
E
V
Y
A
-
A
-------
G
K
A
E
V
V
L
G
N
I
I
K
K
-----
K
--
G
W
R
R
S
-
S
L
V
I
T
T
K
I
F
W
G
G
-----
K
A
------
E
T
E
R
G
L
S
R
K
H
I
I
E
G
L
-
K
A
S
L
E
R
L
Q
L
E
Y
V
D
V
V
F
A
N
R
P
-----
D
-----------------
P
N
-----------------
T
P
---------
M
E
E
T
V
R
A
M
T
H
V
I
N
Q
G
M
A
M
Y
W
G
T
S
R
W
S
S
M
E
I
M
E
A
Y
S
------
V
A
-----
R
-----
Q
F
------
N
L
---
I
P
P
R
C
EQ
A
E
Y
H
M
F
Q
R
-
E
-
K
V
-
E
V
-
Q
L
P
E
L
F
H
K
I
G
V
G
A
M
T
W
S
P
L
A
C
G
I
-
V
S
G
K
----
Y
DSGIPPYSRAS
L
K
G
Y
Q
W
L
K
D
K
I
L
S
E
-
E
G
-
R
R
--------
Q
Q
A
K
L
--
K
E
--
L
Q
A
I
A
E
--------
R
L
-
G
C
---
T
L
P
Q
L
A
I
A
W
C
L
R
N
E
G
V
S
S
V
L
L
G
A
S
N
A
E
Q
L
M
E
----
N
I
G
A
I
Q
V
-
L
P-
K
--
L
S
S
S
I
V
H
E
I
D
S
I
L
G
N
-------------------
21
PsiBlast_CBE
61.90
31%
-84
- C5 -
1LQA
1
TAS_ECOLI
B:
[1-316]
-
M
Q
Y
H
R
I
P
H
S
S
L
E
V
--
S
T
L
G
L
G
T
M
T
-
F
G
----------
E
Q
N
S
E
A
D
A
H
A
Q
L
D
YAVA
Q
G
I
N
L
I
D
V
A
E
M
Y
P
-
V
PPRPETQ
G
L
T
E
T
Y
V
G
N
W
L
A
K
-----
H
--
G
-
S
R
E
-
K
L
I
I
A
S
K
V
S
G
P
S
-----
R
N
N
DKGI-
R
P
D
Q
A
L
D
R
K
N
I
R
E
A
L
-
H
D
S
L
K
R
L
Q
T
D
Y
L
D
L
Y
Q
V
H
W
P
-----
Q
RPTNCFGKLGYSWTDSA
P
A
-----------------
V
S
---------
L
L
D
T
L
D
A
L
A
E
Y
Q
R
A
G
K
I
R
Y
I
G
V
S
N
E
T
A
F
G
V
M
R
Y
L
H
------
L
A
-----
D
-----
K
H
DLPRIV
T
I
---
Q
N
P
------
Y
S
L
L
N
R
-
S
-
F
E
-
V
G
-
L
A
E
-
V
S
Q
Y
E
G
V
E
L
L
A
Y
S
C
L
G
F
G
T
-
L
T
G
K
----
Y
-----------
L
N
G
A
K
P
A
G
--
A
R
N
T
L
F
S
-
R
F
--------
T
R
Y
S
G
--
E
Q
-
T
Q
K
A
V
A
A
Y
V
D
I
A
R
--
R
H
-
G
L
---
D
P
A
Q
M
A
L
A
F
V
R
R
Q
P
F
V
A
S
T
L
L
G
A
T
T
M
D
Q
L
-
K
----------------------------------------------------
8
PsiBlast_PDB
60.99
32%
-124
- C5 -
4WGH
2
?
A:
[39-258]
------------------
I
G
L
G
T
W
Y
-
M
G
E
-
H
---
A
-
A
Q
R
Q
Q
E
V
A
A
L
R
A
G
I
D
----
H
G
L
T
V
I
D
T
A
E
M
Y
A
-
D
-------
G
G
A
E
E
V
V
G
Q
A
I
R
---------
G
-
L
R
D
-
R
V
V
L
V
S
K
V
-
Y
P
W
-----------------
H
A
G
K
A
A
M
H
R
A
C
-
E
N
S
L
R
R
L
Q
T
D
Y
L
D
M
Y
L
L
H
W
R
-----
G
-----------------
D
------------------
I
P
---------
L
Q
E
T
V
E
A
M
E
K
L
V
A
E
G
K
I
R
R
W
G
V
S
N
L
D
T
E
D
M
Q
A
L
W
R
------
T
A
DGE--
H
-----
C
A
------
T
N
---
Q
V
L
------
Y
H
L
A
S
R
-
G
-
I
E
-
Y
D
-
L
L
P
-
W
C
Q
Q
H
S
L
P
V
M
A
Y
---
C
----------------------------------------
P
-
L
A
--------
Q
A
G
R
L
--
R
D
-
G
L
F
Q
H
S
D
I
I
N
M
A
N
-
A
R
--
G
I
---
T
V
A
Q
L
L
L
A
W
V
I
R
H
P
G
--------------------------------------------------------------------
25
PsiBlast_CBE
59.62
32%
-117
- C5 -
1YNP
8
?
A:
[21-225]
-
M
K
K
R
Q
L
G
T
S
D
L
H
V
--
S
E
L
G
F
G
C
M
S
-
L
G
--------
T
D
E
T
K
A
R
R
I
M
D
E
V
L
E
----
L
G
I
N
Y
L
D
T
A
D
L
Y
N
-
Q
-------
G
L
N
E
Q
F
V
G
K
A
L
K
---------
G
-
R
R
Q
-
D
I
I
L
A
T
K
V
-----------------------
S
K
A
Y
I
K
E
A
V
-
K
D
S
L
R
R
L
Q
T
D
Y
I
D
L
Y
Q
L
H
G
G
-----
T
-----------------
I
D
-----------------
D
P
---------
I
D
E
T
I
E
A
F
E
E
L
K
Q
E
G
V
I
R
Y
Y
G
I
S
S
I
R
P
N
V
I
K
E
Y
L
K
------
R
S
-----
N
-----
I
V
------
S
I
---
M
M
Q
------
Y
S
I
L
D
R
-
R
-
P
E
-
E
W
--
F
P
-
L
I
Q
E
H
G
V
S
V
V
V
R
G
P
V
A
R
G
L
-
L
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
56.86
31%
-99
- C5 -
2BP1
2
ARK72_HUMAN
C:
[43-300]
--------------------
L
G
T
M
E
-
M
G
R
-
R
M
-----
D
A
P
A
S
A
A
A
V
R
A
F
L
E
----
R
G
H
T
E
L
D
T
A
F
M
Y
S
-
D
-------
G
Q
S
E
T
I
L
G
G
L
G
L
G
-----
L
--
G
----C
R
V
K
I
A
T
K
-
A
N
P
W
-----
D
G
K
-----
S
L
K
P
D
S
V
R
S
Q
L
-----
E
T
S
L
K
R
L
Q
C
P
Q
V
D
L
F
Y
L
H
A
P
-----
D
-----------------
H
G
-----------------
T
P
---------
V
E
E
T
L
H
A
C
Q
R
L
H
Q
E
G
K
F
V
E
L
G
L
S
N
Y
A
S
W
E
V
A
E
I
C
T
------
L
C
-----
K
SNGWI
L
P
------
T
V
Y--
Q
G
M
------
Y
N
A
T
T
R
-
Q
-
V
E
-
T
E
-
L
F
P
-
C
L
R
H
F
G
L
R
F
Y
A
Y
N
P
L
A
G
G
L
-
L
T
G
K
-------------------
Y
K
Y
E
D
K
D
G
K
Q
P
-
V
G
-
R
F
FGNSWAET
Y
R
N
R
F
WK
E
H
-
H
F
E
A
I
A
L
V
E
K
A
L
Q
-
A
A
Y
-
G
A
SAP
S
V
T
S
A
A
L
R
W
M
-------------------------------------------------------------------------
32
PsiBlast_CBE
56.30
31%
-96
- C5 -
2BP1
2
ARK72_HUMAN
A:
[43-300]
--------------------
L
G
T
M
E
-
M
G
R
-
R
M
-----
D
A
P
A
S
A
A
A
V
R
A
F
L
E
----
R
G
H
T
E
L
D
T
A
F
M
Y
S
-
D
-------
G
Q
S
E
T
I
L
G
G
L
G
L
G
-----
L
--
G
-
G
G
D
C
R
V
K
I
A
T
K
-
A
N
P
W
-----
D
G
K
-----
S
L
K
P
D
S
V
R
S
Q
L
-----
E
T
S
L
K
R
L
Q
C
P
Q
V
D
L
F
Y
L
H
A
P
-----
D
-----------------
H
G
-----------------
T
P
---------
V
E
E
T
L
H
A
C
Q
R
L
H
Q
E
G
K
F
V
E
L
G
L
S
N
Y
A
S
W
E
V
A
E
I
C
T
------
L
C
-----
K
S
N
GWI
L
P
------
T
V
Y
--
Q
G
M
------
Y
N
A
T
T
R
-
Q
-
V
E
-
T
E
-
L
F
P
-
C
L
R
H
F
G
L
R
F
Y
A
Y
N
P
L
A
G
G
L
-
L
T
G
K
-------------------
Y
K
Y
E
D
K
D
G
K
Q
P
-
V
G
-
R
F
FGNSW
A
E
T
Y
R
N
R
F
WK
E
H
-
H
F
E
A
I
A
L
V
E
K
A
L
Q
-
A
A
Y
-
G
A
SAP
S
V
T
S
A
A
L
R
W
M
-------------------------------------------------------------------------
29
PsiBlast_CBE
56.10
31%
-96
- C5 -
2BP1
2
ARK72_HUMAN
D:
[43-300]
--------------------
L
G
T
M
E
-
M
G
R
-
R
M
-----
D
A
P
A
S
A
A
A
V
R
A
F
L
E
----
R
G
H
T
E
L
D
T
A
F
M
Y
S
-
D
-------
G
Q
S
E
T
I
L
G
G
L
G
L
G
-----
L
--
G
-
G
G
D
C
R
V
K
I
A
T
K
-
A
N
P
W
-----
D
G
K
-----
S
L
K
P
D
S
V
R
S
Q
L
-----
E
T
S
L
K
R
L
Q
C
P
Q
V
D
L
F
Y
L
H
A
P
-----
D
-----------------
H
G
-----------------
T
P
---------
V
E
E
T
L
H
A
C
Q
R
L
H
Q
E
G
K
F
V
E
L
G
L
S
N
Y
A
S
W
E
V
A
E
I
C
T
------
L
C
-----
K
SNGWI
L
P
------
T
V
Y--
Q
G
M
------
Y
N
A
T
T
R
-
Q
-
V
E
-
T
E
-
L
F
P
-
C
L
R
H
F
G
L
R
F
Y
A
Y
N
P
L
A
G
G
L
-
L
T
G
K
-------------------
Y
K
Y
E
D
K
D
G
K
Q
P
-
V
G
-
R
F
FGNSWAET
Y
R
N
R
F
WK
E
H
-
H
F
E
A
I
A
L
V
E
K
A
L
Q
-
A
A
Y
-
G
A
SAP
S
V
T
S
A
A
L
R
W
M
-------------------------------------------------------------------------
31
PsiBlast_CBE
55.74
31%
-94
- C5 -
2BP1
2
ARK72_HUMAN
B:
[43-300]
--------------------
L
G
T
M
E
-
M
G
R
-
R
M
-----
D
A
P
A
S
A
A
A
V
R
A
F
L
E
----
R
G
H
T
E
L
D
T
A
F
M
Y
S
-
D
-------
G
Q
S
E
T
I
L
G
G
L
G
L
G
-----
L
--
G
----C
R
V
K
I
A
T
K
-
A
N
P
W
-----
D
G
K
-----
S
L
K
P
D
S
V
R
S
Q
L
-----
E
T
S
L
K
R
L
Q
C
P
Q
V
D
L
F
Y
L
H
A
P
-----
D
-----------------
H
G
-----------------
T
P
---------
V
E
E
T
L
H
A
C
Q
R
L
H
Q
E
G
K
F
V
E
L
G
L
S
N
Y
A
S
W
E
V
A
E
I
C
T
------
L
C
-----
K
S
N
GWI
L
P
------
T
V
Y
--
Q
G
M
------
Y
N
A
T
T
R
-
Q
-
V
E
-
T
E
-
L
F
P
-
C
L
R
H
F
G
L
R
F
Y
A
Y
N
P
L
A
G
G
L
-
L
T
G
K
-------------------
Y
K
Y
E
D
K
D
G
K
Q
P
-
V
G
-
R
F
FGNSW
A
E
T
Y
R
N
R
F
WK
E
H
-
H
F
E
A
I
A
L
V
E
K
A
L
Q
-
A
A
Y
-
G
A
SAP
S
V
T
S
A
A
L
R
W
M
-------------------------------------------------------------------------
38
PsiBlast_CBE
49.70
31%
-112
- C5 -
3H7R
10
AKRC8_ARATH
A:
[31-198]
--------
N
T
G
A
K
L
--
P
C
V
G
L
G
T
Y
A
-
M
V
A
-
T
-------------
A
I
E
Q
A
I
K
----
I
G
Y
R
H
I
D
C
A
S
I
Y
G
-----------
N
E
K
E
I
G
G
V
L
K
K
L
I
G
D
G
F
--
V
-
K
R
E
-
E
L
F
I
T
S
K
L
---
W
-----
S
N
D
-----
H
L
P
E
D
V
P
K
A
-----
L
-
E
K
T
L
Q
D
L
Q
I
D
Y
V
D
L
Y
L
I
H
W
P
ASLKK
E
-----------------
S
L
-----------------
M
P
TPEMLTKPD
I
T
S
T
W
K
A
M
E
A
L
Y
D
S
G
K
A
R
A
I
G
V
S
N
F
S
S
K
K
L
T
D
L
L
N
------
V
A
-------------------
R
V
---
T
P
A
------
V
N
Q
V
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
48.31
38%
-88
- C5 -
5C7H
1
?
A:
[13-203]
----------
G
R
K
V
--
P
A
L
G
Q
G
T
W
R
-
M
G
E
-
N
R
A
K
T
-
A
D
E
V
R
S
L
Q
T
---
G
L
D
----
L
G
M
T
L
I
D
T
A
E
M
Y
G
-
D
-------
G
A
A
E
R
I
V
G
E
A
I
K
---------
G
-
R
R
D
-
E
A
F
V
V
S
K
V
------------------
L
P
S
N
A
S
R
A
G
T
V
A
A
C
-
E
R
S
L
R
N
L
G
I
D
C
V
D
L
Y
L
L
H
W
R
-----
G
-----------------
G
Y
------------------
P
---------
L
A
E
T
V
A
A
F
E
E
L
K
K
A
G
K
I
R
A
W
G
V
S
N
F
D
V
D
D
M
E
E
L
S
A
------
V
P
-----
D
-----
G
G
------
N
V
A
A
N
Q
V
L
------
Y
N
L
A
R
R
-
G
-
I
E
-
F
D
-
L
L
P
-
R
C
R
A
Q
G
V
P
V
M
A
Y
S
P
L
D
E
G
R
-
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
PsiBlast_CBE
46.57
38%
-104
- C5 -
1MZR
2
DKGA_ECOLI
A:
[39-166]
--------------------------
L
G
L
-
G
V
W
Q
A
-
S
N
E
E
V
-
I
T
A
I
Q
K
A
L
E
----
V
G
Y
R
S
I
D
T
A
A
A
Y
-----------
K
N
E
E
G
V
G
K
A
L
K
N
-----
A
--
S
V
N
R
E
-
E
L
F
I
T
T
K
L
---
W
-----
N
D
D
-----
H
-----
K
R
P
R
--
E
A
L
-
L
D
S
L
K
K
L
Q
L
D
Y
I
D
L
Y
L
M
H
W
P
-----
V
-----------------
P
A
-----------------
I
D
H--------
Y
V
E
A
W
K
G
M
I
E
L
Q
K
E
G
L
I
K
S
I
G
V
C
N
F
Q
I
H
H
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------