@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu10160: (2016-06-15 )
MNTIRSQWKDIVTSKKLLIPIIAILFVPLIYSGVFLKAYWDPYGTVDQLPVVVVNQDKGATYEGEKLQIGDDLVKELKDNNNFDWHFSNDLDQSLKDLLNQKYYLVVEIPEDFSKNASTVLDKNPKKLDLKYHTNAGSNYVGATIGEKAIDKLKASVSKEVTEQYTKVIFDNFKDIAKGLSDASSGAKKIDDGTKDAKNGSAQLKENLAKLKESTATISDKTAQLADGAAQVTSGIQSLDSSLGKFQDSSNQIYDKSSQLAAGSGELTSKMNELLAGLQNVQKGTPNLTNGLDQLNSKVQEGSEKAAKAEKIINALDLTKLETAVNNLEKSETAMKEFKKQLTDFENSLKNRDQAFKNVINSSDFLTAEQKSQLINSVEKKLPQVDAPDFDQILSQLPTADQLPDIATIKSSLEDVKAQVAQVKAMPEATSKLYNGAKTIQDAIDRLTEGADKIYNGSQKLTDGQTKLTAGIGEYNKQFAKAKAGSEQLVTGSSQVSGGLFKLLDGSKQVQSGSSKLADGSASLDTGLGKLLDGTGELSSKLKDAADQTGDIDADDQTYGMFADPVKTKDDAIHSVPNYGTGLTPYILSMGLYVGGIMLTVVFPLKEASGRPRNGFEWFFSKFNVMMLVGIIQSLIVATVLLLGIGLEVESTWRFYVFTIITSLAFLAIIQFLATTMGNPGRFIAVIILVLQLGASGGTFPLELLPNFYQVIHGALPMTYSINGFRAVISNGDFGYMWQMAGVLIGIALVMIALSITYFTMLSRKEETSEEQPAS
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80......-...90........100---........110.......120.......130..-.....140......------.150.......160.......170.........180.......190......-.200...-....210.....-....220.-----.------.....230.......240.......250---.......260----..-......270.......280.-----...-...290.......300.......310..--..----...320--.......330........340.......350-----.......360--.....-..370.......-380.....-..390-.......400...--.-...410.......420-.-..-....430.---......440.......450..------....----------.460..-.....470.......480.......490-.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MN
T
I
R
S
Q
W
K
D
I
VTSK
K
L
L
I
P
I
I
A
I
L
F
V
P
L
I
YS
G
V
F
L
K
A
YWDPYGTVDQ
L
P
V
V
V
V
NQDKGATYEGEKLQI
G
D
D
L
V
K
E
L
K
DN-NN
F
D
W
H-FS
N
D
L
D
Q
S
L
K
D
L
LNQ----
K
Y
Y
L
V
V
EIP
E
D
FSK
N
A
S
T
V
LDKNP
K
K
L
D
L
K
Y
HT-NAGSNYVG
A
T
I
G
E
K
------
A
I
D
K
L
K
A
S
V
S
K
E
V
T
E
Q
Y
T
K
V
I
F
--
D
N
F
K
D
I
A
K
G
L
S
D
A
SSGAKKIDDGTKDAK-N
G
S
A
Q
L
K
-
E
N
L
A
K
--
L
K
E
S
T-ATISD
K
T
A
-----
Q
------
L
AD
G
A
A
Q
V
T
S
G
I
Q
S
L
D
S
S
L
G
KFQDSSNQ---IYDKSSQLA-----AG-S
G
E
L
T
S
K
M
N
E
L
L
A
G
L
Q
N
V
QK-----GTP-NLT
N
G
L
D
Q
L
N
S
K
V
Q
EG
S
E
K
A
A
K
A
E
K
I
I
N
--
A
L
----
D
L
T
K
L
E
--
T
A
V
N
NL
E
K
S
-
E
T
A
M
K
E
F
K
K
Q
L
T
D
F
E
N
S
L
K
N
R
-----
D
Q
A
F
K
N
V
INS--SDFL
T
-
A
E
Q
K
S
Q
L
I
N
S
V
E
-
K
KLPQVDA-P
D
F
D
Q
-
I
L
S
QLP
T
A
DQLP
D
--
I
-
A
T
I
K
S
S
L
E
D
V
K
A
Q
V
A
Q
-
V
-KA-M
P
E
A
T
S
K
L
---YN
G
A
K
T
I
Q
D
A
I
D
R
L
T
E
G
A
D
K
I------YNGS----------QKLTDG-Q
T
K
L
T
A
G
I
G
E
Y
N
K
Q
F
A
KAKAGSE
Q
L
VTG-SSQVSG
G
L
F
K
LLDGS
K
Q
V
QSGSSKLADGSA
S
L
D
T
G
L
G
K
L
LDG
T
G
E
L
S
S
K
L
K
D
AADQTGDIDADDQTYGMFADPVKTKD
D
A
IHSVPNYGTG
L
T
P
Y
I
L
S
M
G
L
Y
V
G
G
I
M
L
T
V
V
F
P
LKEASGRPRN
G
F
E
W
F
F
S
K
F
N
V
M
M
L
V
G
I
I
Q
S
L
I
V
A
T
V
L
L
L
GIG
L
E
V
ES
T
W
R
F
Y
V
F
T
I
I
T
S
L
A
F
L
A
I
I
Q
F
L
A
T
TMGNP
G
R
F
I
A
V
I
I
L
V
L
Q
LGASGGT
F
P
L
E
L
L
P
N
F
Y
Q
V
I
HGAL
P
M
T
Y
SING
F
R
A
VISNGD
F
G
Y
M
W
Q
M
A
G
V
L
I
G
I
A
L
V
M
I
A
L
S
I
T
Y
F
T
M
LSRKEETSEEQPAS
18
PsiBlast_PDB
69.10
18%
-48
- C2 -
2CH7
2
MCP2_THEMA
A:
[4-289]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
D
V
Q
T
E
T
F
S
V
A
E
S
I
E
E
I
S
-
K
A
N
E
E
I
T
-
N
Q
L
L
G
--
I
S
K
E
M
-
D
N
I
S
T
R
I
E
-----
S
------
I
S
A
S
V
Q
E
T
T
A
G
S
E
E
I
S
S
A
T
K
N
I
A
D
S
A
Q
Q
A
A
S
F
A
D
Q
S
T
Q
L
A
-----
K
E
-
A
G
D
A
L
K
K
V
I
E
V
T
R
M
I
S
N
S
A
K
-------------
D
V
E
R
V
V
E
S
F
Q
K
G
A
E
E
I
T
S
F
V
E
T
I
N
--
A
I
A
E
Q
T
N
L
L
A
L
N
--
A
A
I
E
A
A
R
A
G
-
E
-
A
G
R
G
F
A
V
V
A
D
E
I
R
K
L
A
E
E
S
-----
Q
Q
A
S
E
N
V
------------
R
R
V
V
N
E
I
R
S
I
A
-
E
D
A
G
K
V
S
S
-----
E
-
I
T
A
R
V
E
E
G
T
K
L
A
D
--
E
-
A
D
E
K
--
L
N
S
I
V
G
A
V
E
R
-
I
-
N
E
-
M
-------------
L
Q
N
I
A
A
A
I
E
E
Q
T
A
A
V
D
E
I
------
T
T
A
M
----------
T
E
N
A
K
N
-
A
E
E
I
T
N
S
V
K
E
V
N
A
R
L
Q
E
I
S
A
S
T
E
E
V
T
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
67.21
18%
-51
- C2 -
3JA6
-
MCP2_THEMA
G:
[224-509]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
D
V
Q
T
E
T
F
S
V
A
E
S
I
E
E
I
S
-
K
A
N
E
E
I
T
-
N
Q
L
L
G
--
I
S
K
E
M
-
D
N
I
S
T
R
I
E
-----
S
------
I
S
A
S
V
Q
E
T
T
A
G
S
E
E
I
S
S
A
T
K
N
I
A
D
S
A
Q
Q
AAS
F
A
D
Q
S
T
Q
L
A
-----
K
E
-
A
G
D
A
L
K
K
V
I
E
V
T
R
M
I
S
N
S
A
K
-------------
D
V
E
R
V
V
E
S
F
Q
K
G
A
E
E
I
T
S
F
V
E
T
I
N
--
A
I
AEQT
N
L
L
A
L
N
--
A
A
I
E
A
A
R
A
G
-
E
-
A
G
R
G
F
A
V
V
A
D
E
I
R
K
L
A
E
E
S
-----
Q
Q
A
S
E
N
V
------------
R
R
V
V
N
E
I
R
S
I
A
-
E
D
A
G
K
V
S
S
-----
E
-
I
T
A
R
V
E
E
G
T
K
L
A
D
--
E
-
A
D
E
K
--
L
N
S
I
V
G
A
V
E
R
-
I
-
N
E
-
M
-------------
L
Q
N
I
A
A
A
I
E
E
Q
T
A
A
V
D
E
I
------
T
T
A
M
----------
T
E
N
A
K
N
-
A
E
E
I
T
N
S
V
K
E
V
N
A
R
L
Q
E
I
S
A
S
T
E
E
V
T
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
57.69
14%
-13
- C1 -
1QOY
-
HLYE_ECOLI
A:
[-4-298]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
M
A
E
I
V
A
-
D
K
T
V
E
--
V
V
K
N
A
-
I
E
T
A
D
G
A
L
-----
D
------
L
Y
N
K
Y
L
D
Q
V
I
P
W
Q
T
F
D
E
T
I
K
E
L
S
R
F
K
Q
E
---
Y
S
Q
A
A
S
V
L
V
-----
G
D
I
K
T
L
L
M
D
S
Q
D
K
Y
F
E
A
T
Q
T
V
Y
E
-----
W
C
G
-
V
A
T
Q
L
L
A
A
Y
I
L
L
F
D
E
Y
N
E
K
K
A
S
A
Q
K
-----
D
I
----
L
I
K
V
L
D
--
D
G
I
T
K
L
N
E
A
-
Q
K
S
L
L
V
S
S
Q
S
F
N
N
A
S
G
K
L
L
A
L
-----
D
S
Q
L
T
N
D
F
S
E
K-
S
S
Y
F
Q
-
S
Q
V
D
K
I
R
K
E
A
Y
A
-
G
A
A
A
G
V
V
V
-
G
P
F
G
L
-
I
I
S
Y
S
I
A
A
G
V
V
E
G
K
L
I
-
P
E
L
K
N
K
L
K
S
V
Q
N
F
F
T
T
-
L
-
S
N
T
V
K
Q
A
N
K
D
I
---
D
A
A
K
L
K
L
T
T
E
I
A
A
I
G
E
I
K
T
E
T
------
E
T
T
R
FYVDYD
D
L
M
L
S
L
L
K
E
A
-
A
K
K
M
I
N
T
C
N
E
Y
Q
K
R
H
G
K
K
T
L
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
55.04
19%
-108
* C3 *
3CNI
2
?
A:
[11-107]
------------------------------------------------
Q
K
V
A
I
V
R
E
D
T
G
T
I
--------
A
E
L
A
E
K
A
L
G
N
---
M
V
D
I
V
Y
A
G
S
D
L
K
E
A
E
E
A
V
K
K
E
----
K
A
P
A
I
I
V
I
P
K
G
F
S
Q
S
L
E
S
G
-----
E
K
A
R
L
E
I
V
W
-
Y
L
R
G
T
G
L
S
E
A
V
S
T
G
------
T
I
S
S
L
I
E
S
L
K
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
53.00
17%
-62
- C3 -
3CNI
2
?
A:
[11-155]
------------------------------------------------
Q
K
V
A
I
V
R
E
D
T
G
--------
T
I
A
E
L
A
E
K
A
L
G
-
N
M
V
D
I
V
Y
A
-
G
S
-
D
L
K
E
A
E
E
A
V
K
K
E
----
K
A
P
A
I
I
V
I
P
K
G
F
S
Q
S
L
E
-----
S
G
E
K
A
R
L
E
I
V
W
-
Y
L
R
G
T
G
L
S
E
A
V
S
T
G
------
T
I
S
S
L
I
E
S
L
K
V
Q
L
A
S
F
L
L
N
D
P
K
KA
Q
L
L
F
D
P
L
E
I
V
Q
H
T
Y
L
R
G
S
L
F
K
N
H
S
P
E
A
I
M
N
V
F
Y
S
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
50.98
21%
28
- C2 -
4UXV
-
EZRA_BACSU
A:
[252-529]
--------------------------------------------------------------------------------------------
L
D
K
E
L
E
N
L
S
N
Q
L
K
R
A
E
H
V
L
M
T
E
L
D
I
D
E
A
S
A
I
L
Q
L
I
D
E
N
I
Q
S
V
---
Y
Q
Q
-
L
E
G
E
V
E
A
G
Q
S
V
L
S
K
M
P
E
L
I
I
A
Y
D
K
L
K
E
E
--
K
E
H
T
K
A
E
T
E
L
V
K
--
E
S
Y
R
L
T
A
G
E
L
G
K
Q
Q
A
F
E
K
R
L
D
E
I
G
K
L
L
S
-
S
V
K
D
K
L
D
A
E
H
V
A
Y
S
L
L
V
E
E
V
-
A
S
I
E
K
Q
I
E
-----
E
------
V
K
K
E
H
A
E
Y
R
E
N
L
Q
A
L
R
K
E
E
L
Q
A
R
E
T
L
S
N
---
L
K
K
T
I
S
E
T
A
R
L
LKT
S
N
-
I
P
G
I
P
S
H
I
Q
E
M
L
---
E
N
A
H
H
-----
H
I
Q
-
E
T
V
N
Q
L
N
E
L
P
L
N
M
E
E
A
G
A
H
L
K
Q
A
E
D
I
V
N
R
A
S
R
----
E
S
E
E
L
V
--
E
Q
V
I
L
I
E
K
I
-
I
Q
F
G
N
R
F
R
S
Q
N
H
I
L
S
E
Q
L
K
E
A
-----
E
R
R
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
50.11
12%
-55
- C1 -
2X0C
-
TLN1_MOUSE
A:
[1352-1659]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
D
P
F
T
K
H
G
Q
K
E
C
D
-
N
A
L
R
Q
L
E
-
T
V
R
E
L
--
L
E
N
P
V
-
Q
P
I
N
D
M
S
-------------
Y
F
G
C
L
D
S
V
M
E
N
S
K
V
L
G
E
A
M
T
G
I
S
Q
N
A
K
N
-----
G
N
L
P
E
F
G
-----
D
A
-
I
A
T
A
S
K
A
L
C
G
F
T
E
A
A
A
Q
A
A
Y
-----
L
V
G
-
V
S
D
P
N
S
Q
A
G
Q
Q
G
L
V
E
-
P
T
Q
F
A
R
A
N
Q
A
I
Q
--
M
A
-----
C
Q
S
L
G
--
E
P
G
C
T
Q
A
Q
V
-
L
S
A
A
T
I
V
A
K
H
T
S
A
L
C
N
S
C
R
L
A
S
A
R
TA
N
P
T
A
K
R
Q
F
V
Q
--
S
A
K
E
V
-
A
N
S
T
A
N
L
V
K
T
I
K
-
A
L
D
G
D
F
T
E
-
E
N
R
A
Q
-
C
R
A
A
T
A
P
L
L
E
A
V
D
--
N
-
L
S
A
F
A
S
N
P
E
F
S
S
V
P
A
Q
-
I
S
P
E
-
G
R
A
A
M
E
P
I
---
V
I
S
A
K
T
M
L
E
S
A
G
G
L
I
Q
T
A
R
A
L
A
V
NPRD
P
P
R
W
----------
S
V
L
A
G
H
-
S
R
T
V
S
D
S
I
K
K
L
I
T
S
M
R
D
K
A
P
G
Q
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
49.27
12%
-6
- C- -
4E40
-
?
A:
[3-247]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
E
I
K
V
E
L
E
-----
D
-------
S
D
D
V
A
A
A
C
E
L
R
A
Q
L
A
G
V
S
I
A
S
G
I
L
L
R
P
---
A
V
I
R
N
A
T
T
E
-----
F
S
-
R
K
K
S
E
D
I
L
A
K
G
G
A
A
V
E
R
A
S
A
-----
A
V
D
-
R
V
S
-
G
L
D
K
T
N
E
T
A
Q
K
V
R
K
A
A
A
V
A
H
H
A
L
E
--
H
V
-----
K
E
E
V
E
--
I
V
A
K
K
V
N
E
I
-
I
E
L
T
A
G
A
T
E
H
A
K
G
A
K
A
N
G
D
A
S
-----
A
V
K
V
S
N
L
L
A
R
--
A
K
E
S
E
N
Q
Y
V
K
E
A
A
E
E
C
S
E
-
S
T
N
Y
D
V
T
A
-
K
S
L
A
A
-
A
L
D
K
L
P
G
V
K
E
D
N
A
V-
K
-
T
T
F
Q
S
I
L
T
S
L
D
N
L
D
K
D
-
V
-
K
S
-
V
E
Q
R
A
E
E
L
---
E
T
A
L
E
K
A
E
R
Q
L
E
K
A
E
K
A
A
E
E
A
------
E
T
E
S
----------
S
K
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
47.31
9%
-39
- C1 -
3DYJ
-
A:
[1975-2290]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
Q
A
C
I
-
T
A
A
S
A
V
S
-
G
I
I
A
D
--
L
D
T
T
I
M
F
A
T
A
G
T
L
N
R
E
GAE
T
------
F
A
D
H
R
E
G
I
L
K
T
A
K
V
L
V
E
D
T
K
V
L
V
Q
N
A
A
------
G
S
Q
E
K
L
A
-----
Q
A
-
A
Q
S
S
V
A
T
I
T
R
L
A
D
V
V
K
L
G
A
A
S
L
GAE
D
P
E
-
T
Q
V
V
L
I
N
A
V
K
D
V
A
K
A
L
G
D
L
I
S
A
T
K
A
A
A
G
--
K
V
----
G
D
D
P
A
V
--
W
Q
L
K
N
S
A
K
V
M
V
T
N
V
T
S
L
L
K
T
V
K
A
V
E
D
E
A
T
K
G
-----
T
R
A
L
E
A
T
T
E
H
--
I
R
Q
E
L
-
A
V
F
C
S
P
E
P
P
A
K
T
-
S
T
P
E
D
F
I
R
M
T
K
G
I
T
M
A
T
A
K
A
V
A
A
G
N
S
C
R
--
Q
-
E
D
V
I
A
T
A
N
L
S
R
R
A
I
A
D
M
L
-
R
A
-
C
K
E
A
A
F
H
P
EVA
P
D
V
R
L
R
A
L
H
Y
G
R
E
C
A
N
G
Y
L
E
L
------
L
D
H
V
----------
L
L
T
L
Q
K
P
N
P
D
L
K
Q
Q
L
T
G
H
S
K
R
V
A
G
S
V
T
E
L
I
Q
A
A
E
A
M
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
47.27
13%
10
- C2 -
3THF
-
SHRM_DROME
A:
[1396-1570]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
N
L
I
K
-----
Q
K
-
M
D
E
L
I
K
H
L
N
Q
K
I
V
S
L
K
R
E
Q
Q
-----
T
I
S
-
E
E
C
S
A
N
D
R
L
G
Q
D
L
F
A
K
L
A
E
K
V
R
--------
P
S
----
E
A
S
K
F
R
--
T
H
V
D
A
V
G
N
I
-
T
S
L
L
L
S
L
S
E
R
L
A
Q
T
E
S
S
L
E
T
R
-----
Q
Q
E
R
G
A
L
E
S
K
--
R
D
L
L
Y
-
E
Q
M
E
E
A
Q
R
L
K
S
D
-
I
E
R
R
G
V
S
I
-
A
G
L
L
A
-
K
N
L
S
A
D
M
C
A
D
Y
D
Y
--
F
-
I
N
M
K
A
K
L
I
A
D
A
R
D
L
A
V
-
R
-
I
K
-
G
S
E
E
Q
L
S
S
---
L
S
D
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
45.68
11%
-15
- C1 -
3PLT
-
LSP1_YEAST
A:
[51-264]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
P
E
L
A
R
K
L
S
Q
L
V
K
T
E
K
G
V
L
R
A
M
E
-
V
V
A
S
E
R
R
-
E
A
A
K
Q
--
L
S
L
W
G
-
A
D
N
D
D
D
V
S
-----
D
------
V
T
D
K
L
G
V
L
I
Y
E
L
G
E
L
Q
D
Q
F
I
D
K
Y
D
Q
Y
R
V
---
T
L
K
S
I
R
N
I
E
-----
A
S
-
V
Q
P
S
R
D
R
K
E
K
I
T
D
E
I
A
H
L
K
Y
-----
K
D
P
-
Q
-
S
T
K
I
P
V
L
E
Q
E
L
V
R
A
E
A
E
S
L
V
A
E
A
Q
L
S
--
N
I
----
T
R
E
K
L
K
--
A
A
Y
S
Y
M
F
D
S
-
L
R
E
L
S
E
K
F
A
L
I
A
G
Y
G
K
A
L
L
E
L
-----
L
D
D
S
P
V
T
P
G
E
A
R
P
A
Y
D
G
-
Y
E
A
S
R
Q
I
I
M
D
A
E
-
S
A
L
E
S
W
T
L
-
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
43.70
27%
104
- C2 -
2D3E
-
GCN4_YEAST (first)
A:
[200-275]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
N
N
L
K
S
L
E
A
Q
A
E
K
Y
S
Q
K
E
D
K
Y
E
E
E
I
K
--
V
L
----
S
-
D
K
L
K
--
E
A
E
T
R
A
E
F
A
-
E
R
S
V
T
K
L
E
K
S
I
D
D
L
E
D
E
L
Y
A
Q
-----
K
L
K
Y
K
A
I
S
E
E
--
L
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
43.06
9%
-26
- C1 -
2OJQ
-
PDC6I_HUMAN
A:
[360-702]
-------------------------------------------------------------------------------------------------------------------
P
V
S
V
Q
Q
S
L
A
A
Y
N
Q
R
K
A
D
L
V
N
R
S
I
A
Q
M
R
E
A
T
T
L
A
N
G
V
L
A
S
L
------
N
L
P
A
A
I
E
D
V
S
G
D
T
V
P
Q
S
I
L
T
K
S
--
R
S
V
I
E
Q
-
G
G
I
Q
T
V
D
Q
L
I
K
E
L
P
E
L
L
Q
R
N
R
-
E
I
L
D
E
S
L
-
R
L
L
D
E
--
E
E
A
T
D
-
N
D
L
R
A
K
F
K
-----
E
RWQRTP
S
N
E
L
Y
K
P
L
R
A
E
G
T
N
F
R
T
V
L
D
K
A
V
Q
A
D
G
Q
---
V
K
E
C
Y
Q
S
H
R
-----
D
T
-
I
V
L
L
C
K
P
E
P
E
L
N
A
A
I
P
S
A
N
P
-----
A
K
T
M
Q
G
S
E
V
V
S
V
L
K
S
L
L
S
N
L
D
E
V
K
K
E
R
E
G
L
E
N
--
D
L
----
K
S
V
N
F
D
M
T
S
K
F
L
T
A
L
A
Q
-
D
G
V
I
N
E
E
A
L
S
V
T
E
L
D
R
V
Y
G
G
L
-----
T
T
K
V
Q
E
S
L
K
K
--
Q
E
G
L
L
-
K
N
I
Q
V
S
H
Q
E
F
S
K
M
K
Q
S
N
N
E
A
N
-
L
R
E
E
V
-
L
K
N
L
A
T
A
Y
D
N
F
V
E
--
L
V
A
N
L
K
E
G
T
K
F
Y
N
E
L
T
E
I
-
L
-
V
R
-
F
Q
N
K
C
S
D
I
---
V
F
A
R
K
T
E
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
39.95
27%
25
- C2 -
3ZX6
1
MCP1_ECOLI
A:
[48-124]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
S
L
M
R
T
V
G
D
V
R
N
G
A
N
A
---
I
Y
S
G
A
S
E
I
A
-----
T
G
-
N
N
D
L
S
S
R
T
E
Q
Q
A
A
S
L
E
E
T
A
A
-----
S
--------
M
E
Q
L
T
A
T
V
K
Q
N
A
E
N
A
R
Q
A
S
H
------
L
----
A
L
S
A
S
E
--
T
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
39.69
47%
2
- C2 -
2JK2
-
TPIS_HUMAN
A:
[123-159]
---------------------------------------------------------------------------------------------------------------------------------------------------
V
I
A
C
I
G
E
K
-------
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
V
I
A
--
D
N
V
K
D
W
S
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
39.53
47%
-7
- C2 -
4POC
-
TPIS_HUMAN
A:
[129-165]
---------------------------------------------------------------------------------------------------------------------------------------------------
V
I
A
C
I
G
E
K
-------
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
V
I
A
--
D
N
V
K
D
W
S
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
39.15
47%
-9
- C2 -
1R2R
4
TPIS_RABIT
C:
[123-159]
---------------------------------------------------------------------------------------------------------------------------------------------------
V
I
A
C
I
G
E
K
-------
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
V
I
A
--
D
N
V
K
D
W
S
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
38.98
47%
-26
- C2 -
1R2R
4
TPIS_RABIT
D:
[123-159]
---------------------------------------------------------------------------------------------------------------------------------------------------
V
I
A
C
I
G
E
K
-------
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
V
I
A
--
D
N
V
K
D
W
S
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
38.67
47%
-3
- C2 -
1WYI
-
TPIS_HUMAN
A:
[123-159]
---------------------------------------------------------------------------------------------------------------------------------------------------
V
I
A
C
I
G
E
K
-------
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
V
I
A
--
D
N
V
K
D
W
S
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
38.57
47%
-17
- C2 -
1R2T
-
TPIS_RABIT
A:
[123-159]
---------------------------------------------------------------------------------------------------------------------------------------------------
V
I
A
C
I
G
E
K
-------
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
V
I
A
--
D
N
V
K
D
W
S
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------