@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu15610: (2016-06-24 )
MGKVYIVGAGPGDPDLLTIKALKAIEKADVILYDRLVNKEILQYAKEQADLIYCGKLPDFHTMKQETINRFLVKYAQKGKMVVRLKGGDPFVFGRGGEEAECLSENGIPFEIIPGITSGIAAAAYAGIPVTHRDAGSNVAFVTGHYKKEEDFEEKWKALATGIDTLVIYMGIKNVQQIERKLLENGRDGSTPAAFIHWGTTDKQKSVFCTVDTLSETVIKENITNPSLIVIGNVVNYHYKLEWFESELKKQDLSEAL
Atome Classification :
(24 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.-----......150..-.....160.......170.......180.......190.......200.......210.......220.......230.......240.......250.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
G
K
V
Y
I
V
GAGPGDP
D
L
L
T
I
K
A
L
K
A
I
E
K
A
D
V
I
L
Y
D
R
LV
N
K
E
I
L
Q
Y
A
K
EQA
D
L
I
Y
CGKLP
D
F
H
T
M
K
Q
E
T
I
N
R
F
L
V
K
Y
A
QKG
K
M
V
V
R
LKGGD
P
F
V
FGRGG
E
E
A
E
C
L
SENGI
P
F
E
IIPGIT
S
G
I
A
A
A
A
YAGIPVTHRDAGS
N
V
A
F
V
T-----GHYK
K
E
E
D
F
E
E
-
K
W
K
A
L
A
T
G
I
D
T
L
V
I
Y
MGI
K
N
V
Q
Q
I
E
R
K
L
L
ENGRDGST
P
A
A
F
I
HWGTTDKQ
K
S
V
F
C
T
V
D
T
L
S
E
T
V
I
K
ENITNP
S
L
I
V
I
GNV
V
N
Y
H
Y
K
L
E
W
F
E
S
E
L
K
K
Q
D
L
S
EAL
22
PsiBlast_CBE
81.90
45%
-136
- C1 -
1PJQ
2
CYSG_SALTY
B:
[216-456]
-
G
E
V
V
L
V
G
A
G
P
G
D
A
G
L
L
T
L
K
G
L
Q
Q
I
Q
Q
A
D
I
V
V
Y
D
R
L
V
S
D
D
I
M
N
L
V
R
R
D
A
D
R
V
F
V
G
K
R
A
--
H
C
V
P
Q
E
E
I
N
Q
I
L
L
R
E
A
Q
K
G
K
R
V
V
R
L
K
G
G
D
P
F
I
F
G
R
G
G
E
E
L
E
T
L
C
H
A
G
I
P
F
S
V
V
P
G
I
T
A
A
S
G
C
S
A
Y
S
G
I
P
L
T
H
R
D
Y
A
Q
S
V
R
L
V
T
-----
G
H
L
K
T
G
G
E
L
D
---
W
E
N
L
A
A
E
K
Q
T
L
V
F
Y
M
G
L
N
Q
A
A
T
I
Q
E
K
L
I
A
F
G
M
Q
A
D
M
P
V
A
L
V
E
N
G
T
S
V
K
Q
R
V
V
H
G
V
L
T
Q
L
G
E
--
L
A
Q
Q
V
E
S
P
A
L
I
I
V
G
R
V
V
A
L
R
D
K
L
N
W
F
S
N
-----------
34
PsiBlast_CBE
81.56
43%
-141
- C1 -
1S4D
2
SUMT_PSEDE
B:
[15-258]
-
G
S
V
W
L
V
G
A
G
P
G
D
P
G
L
L
T
L
H
A
A
N
A
L
R
Q
A
D
V
I
V
H
D
A
L
V
N
E
D
C
L
K
L
A
R
P
G
A
V
L
E
F
A
G
K
R
G
G
K
P
S
P
K
Q
R
D
I
S
L
R
L
V
E
L
A
R
A
G
N
R
V
L
R
L
K
G
G
D
P
F
V
F
G
R
G
G
E
E
A
L
T
L
V
E
H
Q
V
P
F
R
I
V
P
G
I
T
A
G
I
G
G
L
A
Y
A
G
I
P
V
T
H
R
E
V
N
H
A
V
T
F
L
T
-----
G
H
D
S
S
G
-
V
P
D
R
I
N
W
Q
G
I
A
S
G
S
P
V
I
V
M
Y
M
A
M
K
H
I
G
A
I
T
A
N
L
I
A
G
G
R
S
P
D
E
P
V
A
F
V
C
N
A
A
T
P
Q
Q
A
V
L
E
T
T
L
A
R
A
E
A
D
V
A
A
A
G
L
E
P
P
A
I
V
V
V
G
E
V
V
R
L
R
A
A
L
D
W
I
-------------
23
PsiBlast_CBE
81.24
45%
-132
- C1 -
1PJT
1
CYSG_SALTY
B:
[216-456]
-
G
E
V
V
L
V
G
A
G
P
G
D
A
G
L
L
T
L
K
G
L
Q
Q
I
Q
Q
A
D
I
V
V
Y
D
R
L
V
S
D
D
I
M
N
L
V
R
R
D
A
D
R
V
F
V
G
K
R
A
--
H
C
V
P
Q
E
E
I
N
Q
I
L
L
R
E
A
Q
K
G
K
R
V
V
R
L
K
G
G
D
P
F
I
F
G
R
G
G
E
E
L
E
T
L
C
H
A
G
I
P
F
S
V
V
P
G
I
T
A
A
S
G
C
S
A
Y
S
G
I
P
L
T
H
R
D
Y
A
Q
S
V
R
L
V
T
-----
G
H
L
K
T
G
G
E
L
D
---
W
E
N
L
A
A
E
K
Q
T
L
V
F
Y
M
G
L
N
Q
A
A
T
I
Q
E
K
L
I
A
F
G
M
Q
A
D
M
P
V
A
L
V
E
N
G
T
S
V
K
Q
R
V
V
H
G
V
L
T
Q
L
G
E
--
L
A
Q
Q
V
E
S
P
A
L
I
I
V
G
R
V
V
A
L
R
D
K
L
N
W
F
S
N
-----------
21
PsiBlast_CBE
80.83
45%
-135
- C1 -
1PJS
2
CYSG_SALTY
B:
[216-456]
-
G
E
V
V
L
V
G
A
G
P
G
D
A
G
L
L
T
L
K
G
L
Q
Q
I
Q
Q
A
D
I
V
V
Y
D
R
L
V
S
D
D
I
M
N
L
V
R
R
D
A
D
R
V
F
V
G
K
R
A
G
Y
H
C
V
P
Q
E
E
I
N
Q
I
L
L
R
E
A
Q
K
G
K
R
V
V
R
L
K
G
G
D
P
F
I
F
G
R
G
G
E
E
L
E
T
L
C
H
A
G
I
P
F
S
V
V
P
G
I
T
A
A
S
G
C
S
A
Y
S
G
I
P
L
T
H
R
D
Y
A
Q
S
V
R
L
V
T
-----
G
H
---
G
G
E
L
D
---
W
E
N
L
A
A
E
K
Q
T
L
V
F
Y
M
G
L
N
Q
A
A
T
I
Q
E
K
L
I
A
F
G
M
Q
A
D
M
P
V
A
L
V
E
N
G
T
S
V
K
Q
R
V
V
H
G
V
L
T
Q
L
G
E
--
L
A
Q
Q
V
E
S
P
A
L
I
I
V
G
R
V
V
A
L
R
D
K
L
N
W
F
S
N
-----------
31
PsiBlast_CBE
80.72
43%
-146
- C1 -
1S4D
1
SUMT_PSEDE
F:
[15-259]
-
G
S
V
W
L
V
G
A
G
P
G
D
P
G
L
L
T
L
H
A
A
N
A
L
R
Q
A
D
V
I
V
H
D
A
L
V
N
E
D
C
L
K
L
A
R
P
G
A
V
L
E
F
A
G
K
---
K
P
S
P
K
Q
R
D
I
S
L
R
L
V
E
L
A
R
A
G
N
R
V
L
R
L
K
G
G
D
P
F
V
F
G
R
G
G
E
E
A
L
T
L
V
E
H
Q
V
P
F
R
I
V
P
G
I
T
A
G
I
G
G
L
A
Y
A
G
I
P
V
T
H
R
E
V
N
H
A
V
T
F
L
T
-----
G
H
-----
V
P
D
R
I
N
W
Q
G
I
A
S
G
S
P
V
I
V
M
Y
M
A
M
K
H
I
G
A
I
T
A
N
L
I
A
G
G
R
S
P
D
E
P
V
A
F
V
C
N
A
A
T
P
Q
Q
A
V
L
E
T
T
L
A
R
A
E
A
D
V
A
A
A
G
L
E
P
P
A
I
V
V
V
G
E
V
V
R
L
R
A
A
L
D
W
I
-------------
51
HHSearch
80.17
47%
-135
- C1 -
1PJQ
1
CYSG_SALTY
A:
[215-457]
R
G
E
V
V
L
V
G
A
G
P
G
D
A
G
L
L
T
L
K
G
L
Q
Q
I
Q
Q
A
D
I
V
V
Y
D
R
L
V
S
D
D
I
M
N
L
V
R
R
D
A
D
R
V
F
V
G
K
R
---
H
C
V
P
Q
E
E
I
N
Q
I
L
L
R
E
A
Q
K
G
K
R
V
V
R
L
K
G
G
D
P
F
I
F
G
R
G
G
E
E
L
E
T
L
C
H
A
G
I
P
F
S
V
V
P
G
I
T
A
A
S
G
C
S
A
Y
S
G
I
P
L
T
H
R
D
Y
A
Q
S
V
R
L
V
T
-----------
G
--
E
L
-
D
W
E
N
L
A
A
E
K
Q
T
L
V
F
Y
M
G
L
N
Q
A
A
T
I
Q
E
K
L
I
A
F
G
M
Q
A
D
M
P
V
A
L
V
E
N
G
T
S
V
K
Q
R
V
V
H
G
V
L
T
Q
L
G
E
L
A
--
Q
Q
V
E
S
P
A
L
I
I
V
G
R
V
V
A
L
R
D
K
L
N
W
F
S
N
H
----------
1
PsiBlast_PDB
79.72
45%
-139
- C1 -
1PJQ
1
CYSG_SALTY
A:
[216-456]
-
G
E
V
V
L
V
G
A
G
P
G
D
A
G
L
L
T
L
K
G
L
Q
Q
I
Q
Q
A
D
I
V
V
Y
D
R
L
V
S
D
D
I
M
N
L
V
R
R
D
A
D
R
V
F
V
G
K
R
---
H
C
V
P
Q
E
E
I
N
Q
I
L
L
R
E
A
Q
K
G
K
R
V
V
R
L
K
G
G
D
P
F
I
F
G
R
G
G
E
E
L
E
T
L
C
H
A
G
I
P
F
S
V
V
P
G
I
T
A
A
S
G
C
S
A
Y
S
G
I
P
L
T
H
R
D
Y
A
Q
S
V
R
L
V
T
-----------
G
E
L
D
---
W
E
N
L
A
A
E
K
Q
T
L
V
F
Y
M
G
L
N
Q
A
A
T
I
Q
E
K
L
I
A
F
G
M
Q
A
D
M
P
V
A
L
V
E
N
G
T
S
V
K
Q
R
V
V
H
G
V
L
T
Q
L
G
E
--
L
A
Q
Q
V
E
S
P
A
L
I
I
V
G
R
V
V
A
L
R
D
K
L
N
W
F
S
N
-----------
49
HHSearch
79.60
43%
-142
- C1 -
2YBO
1
?
A:
[24-263]
A
G
S
V
A
L
V
G
A
G
P
G
D
P
G
L
L
T
L
R
A
W
A
L
L
Q
Q
A
E
V
V
V
Y
D
R
L
V
A
R
E
L
I
A
L
L
P
E
S
C
Q
R
I
Y
V
G
--------
P
Q
E
E
I
N
E
L
L
V
R
L
A
R
Q
Q
R
R
V
V
R
L
K
G
G
D
P
F
I
F
G
R
G
A
E
E
L
E
R
L
L
E
A
G
V
D
C
Q
V
V
P
G
V
T
A
A
S
G
C
S
T
Y
A
G
I
P
L
T
H
R
D
L
A
Q
S
C
T
F
V
T
-----
G
H
L
Q
N
D
G
R
L
D
L
-
D
W
A
G
L
A
R
G
K
Q
T
L
V
F
Y
M
G
L
G
N
L
A
E
I
A
A
R
L
V
E
H
G
L
A
S
D
T
P
A
A
L
V
S
Q
G
T
Q
A
G
Q
Q
V
T
R
G
A
L
A
E
L
P
A
L
A
R
R
Y
Q
L
K
P
P
T
L
I
V
V
G
Q
V
V
A
L
F
A
E
-----------------
28
PsiBlast_CBE
79.44
43%
-135
- C1 -
1S4D
1
SUMT_PSEDE
I:
[15-258]
-
G
S
V
W
L
V
G
A
G
P
G
D
P
G
L
L
T
L
H
A
A
N
A
L
R
Q
A
D
V
I
V
H
D
A
L
V
N
E
D
C
L
K
L
A
R
P
G
A
V
L
E
F
A
G
K
R
G
G
-
P
S
P
K
Q
R
D
I
S
L
R
L
V
E
L
A
R
A
G
N
R
V
L
R
L
K
G
G
D
P
F
V
F
G
R
G
G
E
E
A
L
T
L
V
E
H
Q
V
P
F
R
I
V
P
G
I
T
A
G
I
G
G
L
A
Y
A
G
I
P
V
T
H
R
E
V
N
H
A
V
T
F
L
T
-----
G
H
D
S
S
--
V
P
D
R
I
N
W
Q
G
I
A
S
G
S
P
V
I
V
M
Y
M
A
M
K
H
I
G
A
I
T
A
N
L
I
A
G
G
R
S
P
D
E
P
V
A
F
V
C
N
A
A
T
P
Q
Q
A
V
L
E
T
T
L
A
R
A
E
A
D
V
A
A
A
G
L
E
P
P
A
I
V
V
V
G
E
V
V
R
L
R
A
A
L
D
W
I
-------------
32
PsiBlast_CBE
79.38
43%
-136
- C1 -
1S4D
1
SUMT_PSEDE
E:
[15-258]
-
G
S
V
W
L
V
G
A
G
P
G
D
P
G
L
L
T
L
H
A
A
N
A
L
R
Q
A
D
V
I
V
H
D
A
L
V
N
E
D
C
L
K
L
A
R
P
G
A
V
L
E
F
A
G
K
R
G
G
K
P
S
P
K
Q
R
D
I
S
L
R
L
V
E
L
A
R
A
G
N
R
V
L
R
L
K
G
G
D
P
F
V
F
G
R
G
G
E
E
A
L
T
L
V
E
H
Q
V
P
F
R
I
V
P
G
I
T
A
G
I
G
G
L
A
Y
A
G
I
P
V
T
H
R
E
V
N
H
A
V
T
F
L
T
-----
G
H
D
S
S
G
--
P
D
R
I
N
W
Q
G
I
A
S
G
S
P
V
I
V
M
Y
M
A
M
K
H
I
G
A
I
T
A
N
L
I
A
G
G
R
S
P
D
E
P
V
A
F
V
C
N
A
A
T
P
Q
Q
A
V
L
E
T
T
L
A
R
A
E
A
D
V
A
A
A
G
L
E
P
P
A
I
V
V
V
G
E
V
V
R
L
R
A
A
L
D
W
I
-------------
29
PsiBlast_CBE
78.83
43%
-146
- C1 -
1S4D
1
SUMT_PSEDE
H:
[15-258]
-
G
S
V
W
L
V
G
A
G
P
G
D
P
G
L
L
T
L
H
A
A
N
A
L
R
Q
A
D
V
I
V
H
D
A
L
V
N
E
D
C
L
K
L
A
R
P
G
A
V
L
E
F
A
G
K
R
G
G
K
P
S
P
K
Q
R
D
I
S
L
R
L
V
E
L
A
R
A
G
N
R
V
L
R
L
K
G
G
D
P
F
V
F
G
R
G
G
E
E
A
L
T
L
V
E
H
Q
V
P
F
R
I
V
P
G
I
T
A
G
I
G
G
L
A
Y
A
G
I
P
V
T
H
R
E
V
N
H
A
V
T
F
L
T
-----
G
H
D
-------
R
I
N
W
Q
G
I
A
S
G
S
P
V
I
V
M
Y
M
A
M
K
H
I
G
A
I
T
A
N
L
I
A
G
G
R
S
P
D
E
P
V
A
F
V
C
N
A
A
T
P
Q
Q
A
V
L
E
T
T
L
A
R
A
E
A
D
V
A
A
A
G
L
E
P
P
A
I
V
V
V
G
E
V
V
R
L
R
A
A
L
D
W
I
-------------
33
PsiBlast_CBE
78.60
43%
-141
- C1 -
1S4D
1
SUMT_PSEDE
D:
[15-258]
-
G
S
V
W
L
V
G
A
G
P
G
D
P
G
L
L
T
L
H
A
A
N
A
L
R
Q
A
D
V
I
V
H
D
A
L
V
N
E
D
C
L
K
L
A
R
P
G
A
V
L
E
F
A
G
-----
P
S
P
K
Q
R
D
I
S
L
R
L
V
E
L
A
R
A
G
N
R
V
L
R
L
K
G
G
D
P
F
V
F
G
R
G
G
E
E
A
L
T
L
V
E
H
Q
V
P
F
R
I
V
P
G
I
T
A
G
I
G
G
L
A
Y
A
G
I
P
V
T
H
R
E
V
N
H
A
V
T
F
L
T
-----
G
H
D
S
S
G
----
R
I
N
W
Q
G
I
A
S
G
S
P
V
I
V
M
Y
M
A
M
K
H
I
G
A
I
T
A
N
L
I
A
G
G
R
S
P
D
E
P
V
A
F
V
C
N
A
A
T
P
Q
Q
A
V
L
E
T
T
L
A
R
A
E
A
D
V
A
A
A
G
L
E
P
P
A
I
V
V
V
G
E
V
V
R
L
R
A
A
L
D
W
I
-------------
26
PsiBlast_CBE
78.57
43%
-135
- C1 -
1S4D
1
SUMT_PSEDE
K:
[15-258]
-
G
S
V
W
L
V
G
A
G
P
G
D
P
G
L
L
T
L
H
A
A
N
A
L
R
Q
A
D
V
I
V
H
D
A
L
V
N
E
D
C
L
K
L
A
R
P
G
A
V
L
E
F
A
G
K
R
G
G
-
P
S
P
K
Q
R
D
I
S
L
R
L
V
E
L
A
R
A
G
N
R
V
L
R
L
K
G
G
D
P
F
V
F
G
R
G
G
E
E
A
L
T
L
V
E
H
Q
V
P
F
R
I
V
P
G
I
T
A
G
I
G
G
L
A
Y
A
G
I
P
V
T
H
R
E
V
N
H
A
V
T
F
L
T
-----
G
H
D
S
S
G
L
V
P
D
R
I
N
W
Q
G
I
A
S
G
S
P
V
I
V
M
Y
M
A
M
K
H
I
G
A
I
T
A
N
L
I
A
G
G
R
S
P
D
E
P
V
A
F
V
C
N
A
A
T
P
Q
Q
A
V
L
E
T
T
L
A
R
A
E
A
D
V
A
A
A
G
L
E
P
P
A
I
V
V
V
G
E
V
V
R
L
R
A
A
L
D
W
I
-------------
3
PsiBlast_PDB
78.43
45%
-132
- C1 -
1PJT
2
CYSG_SALTY
A:
[216-456]
-
G
E
V
V
L
V
G
A
G
P
G
D
A
G
L
L
T
L
K
G
L
Q
Q
I
Q
Q
A
D
I
V
V
Y
D
R
L
V
S
D
D
I
M
N
L
V
R
R
D
A
D
R
V
F
V
G
K
R
---
H
C
V
P
Q
E
E
I
N
Q
I
L
L
R
E
A
Q
K
G
K
R
V
V
R
L
K
G
G
D
P
F
I
F
G
R
G
G
E
E
L
E
T
L
C
H
A
G
I
P
F
S
V
V
P
G
I
T
A
A
S
G
C
S
A
Y
S
G
I
P
L
T
H
R
D
Y
A
Q
S
V
R
L
V
T
-----------
G
E
L
D
---
W
E
N
L
A
A
E
K
Q
T
L
V
F
Y
M
G
L
N
Q
A
A
T
I
Q
E
K
L
I
A
F
G
M
Q
A
D
M
P
V
A
L
V
E
N
G
T
S
V
K
Q
R
V
V
H
G
V
L
T
Q
L
G
E
--
L
A
Q
Q
V
E
S
P
A
L
I
I
V
G
R
V
V
A
L
R
D
K
L
N
W
F
S
N
-----------
6
PsiBlast_PDB
78.35
43%
-139
- C1 -
1S4D
3
SUMT_PSEDE
A:
[15-258]
-
G
S
V
W
L
V
G
A
G
P
G
D
P
G
L
L
T
L
H
A
A
N
A
L
R
Q
A
D
V
I
V
H
D
A
L
V
N
E
D
C
L
K
L
A
R
P
G
A
V
L
E
F
A
G
K
R
G
--
P
S
P
K
Q
R
D
I
S
L
R
L
V
E
L
A
R
A
G
N
R
V
L
R
L
K
G
G
D
P
F
V
F
G
R
G
G
E
E
A
L
T
L
V
E
H
Q
V
P
F
R
I
V
P
G
I
T
A
G
I
G
G
L
A
Y
A
G
I
P
V
T
H
R
E
V
N
H
A
V
T
F
L
T
-----
G
H
D
-------
R
I
N
W
Q
G
I
A
S
G
S
P
V
I
V
M
Y
M
A
M
K
H
I
G
A
I
T
A
N
L
I
A
G
G
R
S
P
D
E
P
V
A
F
V
C
N
A
A
T
P
Q
Q
A
V
L
E
T
T
L
A
R
A
E
A
D
V
A
A
A
G
L
E
P
P
A
I
V
V
V
G
E
V
V
R
L
R
A
A
L
D
W
I
-------------
30
PsiBlast_CBE
78.31
43%
-135
- C1 -
1S4D
1
SUMT_PSEDE
G:
[15-258]
-
G
S
V
W
L
V
G
A
G
P
G
D
P
G
L
L
T
L
H
A
A
N
A
L
R
Q
A
D
V
I
V
H
D
A
L
V
N
E
D
C
L
K
L
A
R
P
G
A
V
L
E
F
A
G
K
R
G
G
K
P
S
P
K
Q
R
D
I
S
L
R
L
V
E
L
A
R
A
G
N
R
V
L
R
L
K
G
G
D
P
F
V
F
G
R
G
G
E
E
A
L
T
L
V
E
H
Q
V
P
F
R
I
V
P
G
I
T
A
G
I
G
G
L
A
Y
A
G
I
P
V
T
H
R
E
V
N
H
A
V
T
F
L
T
-----
G
H
D
S
S
G
--
P
D
R
I
N
W
Q
G
I
A
S
G
S
P
V
I
V
M
Y
M
A
M
K
H
I
G
A
I
T
A
N
L
I
A
G
G
R
S
P
D
E
P
V
A
F
V
C
N
A
A
T
P
Q
Q
A
V
L
E
T
T
L
A
R
A
E
A
D
V
A
A
A
G
L
E
P
P
A
I
V
V
V
G
E
V
V
R
L
R
A
A
L
D
W
I
-------------
27
PsiBlast_CBE
77.91
43%
-144
- C1 -
1S4D
1
SUMT_PSEDE
J:
[15-258]
-
G
S
V
W
L
V
G
A
G
P
G
D
P
G
L
L
T
L
H
A
A
N
A
L
R
Q
A
D
V
I
V
H
D
A
L
V
N
E
D
C
L
K
L
A
R
P
G
A
V
L
E
F
A
G
K
----
P
S
P
K
Q
R
D
I
S
L
R
L
V
E
L
A
R
A
G
N
R
V
L
R
L
K
G
G
D
P
F
V
F
G
R
G
G
E
E
A
L
T
L
V
E
H
Q
V
P
F
R
I
V
P
G
I
T
A
G
I
G
G
L
A
Y
A
G
I
P
V
T
H
R
E
V
N
H
A
V
T
F
L
T
-----
G
H
D
-------
R
I
N
W
Q
G
I
A
S
G
S
P
V
I
V
M
Y
M
A
M
K
H
I
G
A
I
T
A
N
L
I
A
G
G
R
S
P
D
E
P
V
A
F
V
C
N
A
A
T
P
Q
Q
A
V
L
E
T
T
L
A
R
A
E
A
D
V
A
A
A
G
L
E
P
P
A
I
V
V
V
G
E
V
V
R
L
R
A
A
L
D
W
I
-------------
48
HHSearch
77.72
42%
-134
- C1 -
1S4D
3
SUMT_PSEDE
A:
[14-265]
K
G
S
V
W
L
V
G
A
G
P
G
D
P
G
L
L
T
L
H
A
A
N
A
L
R
Q
A
D
V
I
V
H
D
A
L
V
N
E
D
C
L
K
L
A
R
P
G
A
V
L
E
F
A
G
K
R
G
--
P
S
P
K
Q
R
D
I
S
L
R
L
V
E
L
A
R
A
G
N
R
V
L
R
L
K
G
G
D
P
F
V
F
G
R
G
G
E
E
A
L
T
L
V
E
H
Q
V
P
F
R
I
V
P
G
I
T
A
G
I
G
G
L
A
Y
A
G
I
P
V
T
H
R
E
V
N
H
A
V
T
F
L
T
-----
G
H
D
------
R
I
-
N
W
Q
G
I
A
S
G
S
P
V
I
V
M
Y
M
A
M
K
H
I
G
A
I
T
A
N
L
I
A
G
G
R
S
P
D
E
P
V
A
F
V
C
N
A
A
T
P
Q
Q
A
V
L
E
T
T
L
A
R
A
E
A
D
V
A
A
A
G
L
E
P
P
A
I
V
V
V
G
E
V
V
R
L
R
A
A
L
D
W
I
G
A
L
D
G
R
K
------
4
PsiBlast_PDB
77.40
43%
-143
- C1 -
2YBO
1
?
A:
[25-258]
-
G
S
V
A
L
V
G
A
G
P
G
D
P
G
L
L
T
L
R
A
W
A
L
L
Q
Q
A
E
V
V
V
Y
D
R
L
V
A
R
E
L
I
A
L
L
P
E
S
C
Q
R
I
Y
V
G
--------
P
Q
E
E
I
N
E
L
L
V
R
L
A
R
Q
Q
R
R
V
V
R
L
K
G
G
D
P
F
I
F
G
R
G
A
E
E
L
E
R
L
L
E
A
G
V
D
C
Q
V
V
P
G
V
T
A
A
S
G
C
S
T
Y
A
G
I
P
L
T
H
R
D
L
A
Q
S
C
T
F
V
T
-----
G
H
L
Q
N
D
G
R
L
D
L
-
D
W
A
G
L
A
R
G
K
Q
T
L
V
F
Y
M
G
L
G
N
L
A
E
I
A
A
R
L
V
E
H
G
L
A
S
D
T
P
A
A
L
V
S
Q
G
T
Q
A
G
Q
Q
V
T
R
G
A
L
A
E
L
P
A
L
A
R
R
Y
Q
L
K
P
P
T
L
I
V
V
G
Q
V
V
----------------------
24
PsiBlast_CBE
77.36
43%
-144
- C1 -
1S4D
13
SUMT_PSEDE
M:
[15-258]
-
G
S
V
W
L
V
G
A
G
P
G
D
P
G
L
L
T
L
H
A
A
N
A
L
R
Q
A
D
V
I
V
H
D
A
L
V
N
E
D
C
L
K
L
A
R
P
G
A
V
L
E
F
A
G
K
R
G
G
-
P
S
P
K
Q
R
D
I
S
L
R
L
V
E
L
A
R
A
G
N
R
V
L
R
L
K
G
G
D
P
F
V
F
G
R
G
G
E
E
A
L
T
L
V
E
H
Q
V
P
F
R
I
V
P
G
I
T
A
G
I
G
G
L
A
Y
A
G
I
P
V
T
H
R
E
V
N
H
A
V
T
F
L
T
-----
G
H
D
-------
R
I
N
W
Q
G
I
A
S
G
S
P
V
I
V
M
Y
M
A
M
K
H
I
G
A
I
T
A
N
L
I
A
G
G
R
S
P
D
E
P
V
A
F
V
C
N
A
A
T
P
Q
Q
A
V
L
E
T
T
L
A
R
A
E
A
D
V
A
A
A
G
L
E
P
P
A
I
V
V
V
G
E
V
V
R
L
R
A
A
L
D
W
I
-------------
5
PsiBlast_PDB
77.06
43%
-147
- C1 -
2YBQ
2
?
A:
[23-256]
-
G
S
V
A
L
V
G
A
G
P
G
D
P
G
L
L
T
L
R
A
W
A
L
L
Q
Q
A
E
V
V
V
Y
D
R
L
V
A
R
E
L
I
A
L
L
P
E
S
C
Q
R
I
Y
V
G
--------
P
Q
E
E
I
N
E
L
L
V
R
L
A
R
Q
Q
R
R
V
V
R
L
K
G
G
D
P
F
I
F
G
R
G
A
E
E
L
E
R
L
L
E
A
G
V
D
C
Q
V
V
P
G
V
T
A
A
S
G
C
S
T
Y
A
G
I
P
L
T
H
R
D
L
A
Q
S
C
T
F
V
T
-----
G
H
L
Q
----
L
D
L
-
D
W
A
G
L
A
R
G
K
Q
T
L
V
F
Y
M
G
L
G
N
L
A
E
I
A
A
R
L
V
E
H
G
L
A
S
D
T
P
A
A
L
V
S
Q
G
T
Q
A
G
Q
Q
V
T
R
G
A
L
A
E
L
P
A
L
A
R
R
Y
Q
L
K
P
P
T
L
I
V
V
G
Q
V
V
----------------------
2
PsiBlast_PDB
75.46
45%
-138
- C1 -
1PJS
3
CYSG_SALTY
A:
[216-456]
-
G
E
V
V
L
V
G
A
G
P
G
D
A
G
L
L
T
L
K
G
L
Q
Q
I
Q
Q
A
D
I
V
V
Y
D
R
L
V
S
D
D
I
M
N
L
V
R
R
D
A
D
R
V
F
V
--------
V
P
Q
E
E
I
N
Q
I
L
L
R
E
A
Q
K
G
K
R
V
V
R
L
K
G
G
D
P
F
I
F
G
R
G
G
E
E
L
E
T
L
C
H
A
G
I
P
F
S
V
V
P
G
I
T
A
A
S
G
C
S
A
Y
S
G
I
P
L
T
H
R
D
Y
A
Q
S
V
R
L
V
T
-----------
G
E
L
D
---
W
E
N
L
A
A
E
K
Q
T
L
V
F
Y
M
G
L
N
Q
A
A
T
I
Q
E
K
L
I
A
F
G
M
Q
A
D
M
P
V
A
L
V
E
N
G
T
S
V
K
Q
R
V
V
H
G
V
L
T
Q
L
G
E
--
L
A
Q
Q
V
E
S
P
A
L
I
I
V
G
R
V
V
A
L
R
D
K
L
N
W
F
S
N
-----------
8
PsiBlast_PDB
69.39
39%
-124
- C1 -
1V9A
2
?
A:
[1-223]
-
G
R
V
Y
L
V
G
A
G
P
G
D
P
E
L
L
T
L
K
A
Y
R
L
L
K
E
A
P
V
V
L
Y
D
R
L
V
D
E
R
V
L
A
L
A
--
P
G
E
K
V
Y
V
G
K
-------
K
Q
E
E
I
H
R
L
L
L
R
H
A
R
A
H
P
F
V
V
R
L
K
G
G
D
P
M
V
F
G
R
G
G
E
E
V
L
F
L
L
R
H
G
V
P
V
E
V
V
P
G
V
T
S
L
L
A
----
S
G
L
P
L
T
H
R
G
L
A
H
G
F
A
A
V
S
GVLEG
G
G
Y
P
D
L
R
P
F
A
R
---------
V
P
T
L
V
V
L
M
G
V
G
R
R
V
W
I
A
K
E
L
L
R
L
G
R
D
P
R
E
P
T
L
F
V
E
R
A
S
T
P
K
E
R
R
V
H
A
R
L
E
E
V
A
E
G
--
K
V
E
V
R
P
P
A
L
W
I
L
G
E
V
V
R
---------------------
36
PsiBlast_CBE
68.57
39%
-127
- C1 -
1V9A
2
?
B:
[1-223]
-
G
R
V
Y
L
V
G
A
G
P
G
D
P
E
L
L
T
L
K
A
Y
R
L
L
K
E
A
P
V
V
L
Y
D
R
L
V
D
E
R
V
L
A
L
A
--
P
G
E
K
V
Y
V
G
K
----------
E
I
H
R
L
L
L
R
H
A
R
A
H
P
F
V
V
R
L
K
G
G
D
P
M
V
F
G
R
G
G
E
E
V
L
F
L
L
R
H
G
V
P
V
E
V
V
P
G
V
T
S
L
L
A
----
S
G
L
P
L
T
H
R
G
L
A
H
G
F
A
A
V
S
GVLEG
G
G
Y
P
D
L
R
P
F
A
R
---------
V
P
T
L
V
V
L
M
G
V
G
R
R
V
W
I
A
K
E
L
L
R
L
G
R
D
P
R
E
P
T
L
F
V
E
R
A
S
T
P
K
E
R
R
V
H
A
R
L
E
E
V
A
E
G
--
K
V
E
V
R
P
P
A
L
W
I
L
G
E
V
V
R
---------------------