@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu15940: (2016-06-25 )
MFLKRLDVIGFKSFAERISVDFVKGVTAVVGPNGSGKSNITDAIRWVLGEQSARSLRGGKMEDIIFAGSDSRKRLNLAEVTLTLDNDDHFLPIDFHEVSVTRRVYRSGESEFLINNQPCRLKDIIDLFMDSGLGKEAFSIISQGKVEEILSSKAEDRRSIFEEAAGVLKYKTRKKKAENKLFETQDNLNRVEDILHELEGQVEPLKIQASIAKDYLEKKKELEHVEIALTAYDIEELHGKWSTLKEKVQMAKEEELAESSAISAKEAKIEDTRDKIQALDESVDELQQVLLVTSEELEKLEGRKEVLKERKKNAVQNQEQLEEAIVQFQQKETVLKEELSKQEAVFETLQAEVKQLRAQVKEKQQALSLHNENVEEKIEQLKSDYFELLNSQASIRNELQLLDDQMSQSAVTLQRLADNNEKHLQERHDISARKAACETEFARIEQEIHSQVGAYRDMQTKYEQKKRQYEKNESALYQAYQYVQQARSKKDMLETMQGDFSGFYQGVKEVLKAKERLGGIRGAVLELISTEQKYETAIEIALGASAQHVVTDDEQSARKAIQYLKQNSFGRATFLPLSVIRDRQLQSRDAETAARHSSFLGVASELVTFDPAYRSVIQNLLGTVLITEDLKGANELAKLLGHRYRIVTLEGDVVNPGGSMTGGAVKKKNNSLLGRSRELEDVTKRLAEMEEKTALLEQEVKTLKHSIQDMEKKLADLRETGEGLRLKQQDVKGQLYELQVAEKNINTHLELYDQEKSALSESDEERKVRKRKLEEELSAVSEKMKQLEEDIDRLTKQKQTQSSTKESLSNELTELKIAAAKKEQACKGEEDNLARLKKELTETELALKEAKEDLSFLTSEMSSSTSGEEKLEEAAKHKLNDKTKTIELIALRRDQRIKLQHGLDTYERELKEMKRLYKQKTTLLKDEEVKLGRMEVELDNLLQYLREEYSLSFEGAKEKYQLETDPEEARKRVKLIKLAIEELGTVNLGSIDEFERVNERYKFLSEQKEDLTEAKNTLFQVIEEMDEEMTKRFNDTFVQIRSHFDQVFRSLFGGGRAELRLTDPNDLLHSGVEIIAQPPGKKLQNLNLLSGGERALTAIALLFSILKVRPVPFCVLDEVEAALDEANVFRFAQYLKKYSSDTQFIVITHRKGTMEEADVLYGVTMQESGVSKVISVKLEETKEFVQ
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530........540.......550.......560.--......570.....---..580.......590.......600----........610........620-.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030......1040......1050.......1060......1070......1080......1090......1100......1110......1120......1130.....-.1140......1150......1160.-.....1170......1180...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MF
L
K
R
L
D
VI
G
F
K
S
F
A
E
R
I
S
V
D
F
V
KG
V
T
A
V
VGPNGSGK
S
N
I
T
D
A
I
R
W
V
LGEQ
S
A
R
S
LRGGKM
E
D
I
I
F
AGSDSR
K
R
L
N
L
A
E
V
T
L
T
LDNDD
H
F
L
P
I
D
F
H
E
V
S
V
T
R
R
V
Y
RSGES
E
F
L
INNQPC
R
L
K
D
I
I
D
L
F
M
DSGL
G
K
E
A
F
S
I
I
SQ
G
K
V
E
E
I
L
S
S
K
A
E
D
R
R
S
I
F
E
E
A
A
G
V
L
K
Y
K
T
R
KKKAENKLFETQD
N
L
N
R
V
E
D
I
L
H
E
LEGQVE
P
L
K
I
Q
A
S
I
A
K
D
Y
L
E
K
K
KEL
E
H
V
E
I
A
L
T
AY
D
I
E
E
L
H
G
K
W
S
T
L
K
E
K
V
Q
M
A
K
E
E
E
L
A
E
SSAISAKEAK
I
E
D
T
R
D
K
I
Q
A
L
D
E
S
V
D
E
L
Q
Q
V
L
L
V
T
S
E
E
L
E
K
L
E
G
R
K
E
V
L
K
E
R
K
K
NAVQ
N
Q
E
Q
L
E
E
A
I
V
Q
F
Q
Q
K
E
T
V
L
K
E
E
L
S
K
Q
E
A
V
F
E
T
L
Q
A
E
V
K
Q
L
R
A
Q
V
K
E
K
Q
Q
A
L
S
LHNE
N
V
E
E
K
I
E
Q
L
K
S
D
Y
F
E
L
L
N
S
Q
A
S
I
R
N
E
L
Q
L
L
D
D
Q
M
S
Q
S
A
V
T
L
Q
R
L
ADN
N
E
K
H
L
Q
E
R
HD
I
S
A
R
K
A
A
C
E
T
E
F
A
R
I
E
Q
E
I
H
S
Q
V
G
A
Y
R
D
M
Q
T
K
Y
E
Q
K
K
R
Q
YE
K
N
E
S
A
L
Y
Q
A
Y
Q
Y
V
Q
Q
A
R
S
K
K
D
M
L
E
T
M
Q
G
D
F
S
G
F
Y
Q
G
V
K
E
V
L
K
A
K
E
R
LG
G
I
R
G
A
V
L
E
L
IST-
E
Q
K
Y
E
T
A
I
E
I
A
LGASA
Q
H
V
VTD
D
E
Q
S
A
R
K
A
I
Q
Y
--
L
K
QNSFGR
A
T
F
L
P
L
---
S
V
I
RDRQLQSR
D
A
E
T
A
A
R
H
S
S
F
L
G
-----
V
A
S
E
LVTF
D
-
P
A
Y
R
S
V
I
Q
N
L
L
G
-
T
V
L
I
T
E
D
LK
G
A
N
E
L
A
K
L
LGH
R
Y
R
I
V
T
LEG
D
V
VNPGGSMTG
G
A
V
KKKNNSLLGRS
R
E
L
E
D
V
T
K
R
L
A
E
M
E
E
K
T
A
L
L
E
Q
E
V
K
T
L
K
H
S
I
Q
D
M
E
K
K
L
A
D
L
R
ETGEGL
R
L
K
Q
Q
DVK
G
Q
L
Y
E
L
Q
V
AEKNINT
H
L
E
L
Y
D
Q
E
K
S
ALSE
S
D
E
E
R
K
V
R
K
R
K
L
E
E
E
L
S
A
V
S
E
K
M
K
Q
L
E
E
D
I
D
R
L
T
K
Q
K
QTQ
S
S
T
K
E
S
L
S
N
E
L
T
E
L
K
IAAAK
K
E
Q
ACKGEE
D
N
L
A
R
L
K
K
E
L
T
E
T
E
L
A
L
K
E
A
K
E
D
L
S
F
L
T
S
E
MSSSTS
G
E
E
K
L
E
E
A
A
K
H
KLNDKT
K
T
I
E
L
I
A
LRRD
Q
R
I
K
LQHG
L
D
T
Y
E
R
E
L
K
E
M
K
R
L
Y
K
Q
K
T
TLLKDEEVKLG
R
M
E
V
E
L
D
N
L
L
Q
Y
L
R
E
EYSLSFEGAK
E
K
Y
QLET
D
P
E
E
A
R
K
R
V
K
L
I
K
L
A
I
E
E
LGTVNLG
S
I
D
E
F
E
R
V
N
E
R
Y
K
F
L
S
E
Q
K
E
D
L
T
E
A
K
N
T
L
F
Q
V
I
E
E
M
D
E
E
M
T
K
RF
N
D
T
F
V
Q
I
R
S
H
F
D
Q
V
F
R
S
L
-FGGG
R
A
E
L
R
LT
D
P
N
D
L
L
H
S
G
V
E
I
I
AQPPGKKLQNLNLLSG
G
E
R
A
L
T
A
I
A
L
L
F
S
I
L
KVRPV
P
F
C
V
L
D
E
V
E
A
A
L
D
E
A
N
V
F
R
F
A
Q
Y
L
K
K
Y-SSDT
Q
F
I
V
I
THRKGTMEEA
D
V
L
Y
G
V
T
-MQESGVS
K
V
I
S
V
K
L
E
E
T
K
E
F
VQ
97
HHSearch
86.62
100%
0
- C- -
3ZGX
-
SMC_BACSU
A:
[1-971]
M
F
L
K
R
L
D
V
I
G
F
K
S
F
A
E
R
I
S
V
D
F
V
K
G
V
T
A
V
V
G
P
---
G
K
S
N
I
T
D
A
I
R
W
V
L
G
E
Q
S
------------------------
L
A
E
V
T
L
T
L
D
N
D
D
H
F
L
P
I
D
-
H
E
V
S
V
T
R
R
V
Y
R
S
G
E
S
E
F
L
I
N
N
Q
P
C
R
L
K
D
I
I
D
L
F
M
D
-----
E
A
F
S
I
I
S
Q
G
K
V
E
E
I
L
S
S
K
A
E
D
R
R
S
I
F
E
E
A
A
G
V
L
K
Y
K
T
R
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
109
HHSearch
72.79
100%
-102
- C1 -
3ZGX
-
SMC_BACSU
A:
[1022-1175]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
E
M
D
E
E
M
T
K
R
F
N
D
T
F
V
Q
I
R
S
H
F
D
Q
V
F
R
S
L
-
F
G
G
G
R
A
E
L
R
L
T
D
P
N
D
L
L
H
S
G
V
E
I
I
A
Q
P
P
G
K
K
L
Q
N
L
N
L
L
S
G
G
E
R
A
L
T
A
I
A
L
L
F
S
I
L
K
V
R
P
V
P
F
C
V
L
D
E
V
E
A
A
L
D
E
A
N
V
F
R
F
A
Q
Y
L
K
K
Y
-
S
S
D
T
Q
F
I
V
I
T
H
R
K
G
T
M
E
E
A
D
V
L
Y
G
V
T
-
M
----
V
S
K
V
I
S
-----------
115
Fugue
69.35
32%
-167
- C3 -
1GXJ
-
?
A:
[498-658]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
F
S
R
A
V
R
A
V
F
E
E
K
E
R
F
P
G
L
V
D
V
V
S
N
L
I
E
V
-
D
E
K
Y
S
L
A
V
S
V
L
L
G
G
T
A
Q
N
I
V
V
R
N
V
D
T
A
K
A
I
V
E
F
--
L
K
Q
N
E
A
G
R
V
T
I
L
P
L
---
D
L
I
D
---
G
S
F
N
R
I
S
G
L
E
N
E
R
G
F
V
G
-----
Y
A
V
D
L
V
K
F
P
-
S
D
L
E
V
L
G
G
F
L
F
G
-
N
S
V
V
V
E
T
L
D
D
A
I
R
M
K
K
K
Y
R
L
N
T
R
I
A
T
L
D
G
E
L
I
S
G
R
G
A
I
T
G
G
R
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
68.74
31%
-161
- C3 -
1GXJ
-
?
A:
[498-658]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
F
S
R
A
V
R
A
V
F
E
E
K
E
R
F
P
G
L
V
D
V
V
S
N
L
I
E
V
-
D
E
K
Y
S
L
A
V
S
V
L
L
G
G
T
A
Q
N
I
V
V
R
N
V
D
T
A
K
A
I
V
E
F
--
L
K
Q
N
E
A
G
R
V
T
I
L
P
L
---
D
L
I
D
G
S
F
N
R
I
S
G
L
E
N
---
E
R
G
F
V
G
-----
Y
A
V
D
L
V
K
F
P
-
S
D
L
E
V
L
G
G
F
L
F
G
-
N
S
V
V
V
E
T
L
D
D
A
I
R
M
K
K
K
Y
R
L
N
T
R
I
A
T
L
D
G
E
L
I
S
G
R
G
A
I
T
G
G
R
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
65.55
38%
-126
- C1 -
1W1W
2
SMC1_YEAST
B:
[269-428]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
K
T
F
D
Y
V
S
D
H
L
D
A
I
Y
R
E
L
T---
G
N
A
S
L
T
I
E
D
E
D
E
P
F
N
A
G
I
K
Y
H
A
T
P
P
L
K
R
F
K
D
M
E
Y
L
S
G
G
E
K
T
V
A
A
L
A
L
L
F
A
I
N
S
Y
Q
P
S
P
F
F
V
L
D
E
V
D
A
A
L
D
I
T
N
V
Q
R
I
A
A
Y
I
R
R
H
R
N
P
D
L
Q
F
I
V
I
S
L
K
N
T
M
F
E
K
S
D
A
L
V
G
V
Y
R
Q
Q
Q
E
N
S
S
K
I
I
T
L
D
L
S
N
Y
-----
99
HHSearch
65.48
26%
-166
- C3 -
4U4P
-
SMC4_HUMAN
B:
[612-755]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
P
G
I
Y
G
R
L
G
D
L
G
A
I
-
D
E
K
Y
D
V
A
I
S
S
C
C
H
-
A
L
D
Y
I
V
V
D
S
I
D
I
A
Q
E
C
V
N
F
--
L
K
R
Q
N
I
G
V
A
T
F
I
G
L
---
D
K
M
A
V
W
A
K
K
M
T
----
E
I
Q
T
P
E
N
T
P
-----
R
L
F
D
L
V
K
V
K
D
E
K
I
R
Q
A
F
Y
F
A
L
R
-
D
T
L
V
A
D
N
L
D
Q
A
T
R
V
A
Y
Q
K
D
R
R
W
R
V
V
T
L
Q
G
Q
I
I
E
Q
S
G
T
M
T
G
G
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
65.16
38%
-130
- C1 -
1W1W
2
SMC1_YEAST
C:
[269-428]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
K
T
F
D
Y
V
S
D
H
L
D
A
I
Y
R
E
L
T---
G
N
A
S
L
T
I
E
D
E
D
E
P
F
N
A
G
I
K
Y
H
A
T
P
P
L
K
R
F
K
D
M
E
Y
L
S
G
G
E
K
T
V
A
A
L
A
L
L
F
A
I
N
S
Y
Q
P
S
P
F
F
V
L
D
E
V
D
A
A
L
D
I
T
N
V
Q
R
I
A
A
Y
I
R
R
H
R
N
P
D
L
Q
F
I
V
I
S
L
K
N
T
M
F
E
K
S
D
A
L
V
G
V
Y
R
Q
Q
Q
E
N
S
S
K
I
I
T
L
D
L
S
N
Y
-----
9
PsiBlast_PDB
64.81
30%
-160
- C3 -
4RSJ
-
SMC_PYRFU
A:
[519-719]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
G
G
I
Y
G
T
L
A
E
L
I
K
V
K
D
E
A
Y
A
L
A
I
E
V
A
L
G
N
R
A
D
N
V
V
V
E
D
E
L
V
A
E
K
A
I
K
Y
--
L
K
E
H
K
L
G
R
L
T
F
L
P
L
---
N
K
I
K
P
K
H
V
D
----------
S
S
V
G
L
-----
P
A
V
D
V
I
E
Y
D
-
Q
K
I
E
N
A
V
K
F
A
L
G
-
D
T
V
I
V
N
S
M
----
E
E
A
R
P
H
I
G
K
V
R
M
V
T
I
E
G
E
L
Y
E
R
S
G
A
I
T
G
G
H
F
----
L
A
V
--------
D
T
T
K
----
L
R
E
K
V
E
S
L
R
R
R
K
E
A
L
E
G
E
L
N
S
L
K
I
E
L
R
S
L
E
N
A
S
F
E
L
R
I
K
L
S
D
E
K
---
K
E
L
E
L
A
S
K
D
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
64.74
30%
-149
- C3 -
4U4P
-
SMC2_HUMAN
A:
[522-706]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
K
G
L
V
A
S
L
I
S
V
K
D
T
S
A
T
T
A
L
E
L
V
A
G
E
R
L
Y
N
V
V
V
D
T
E
V
T
G
K
K
L
L
E
R
GE
L
K
R
----
R
Y
T
I
I
P
L
---
N
K
I
S
A
R
C
I
A
P
---
E
T
L
R
V
A
Q
N
L
V
G
PDNVH
V
A
L
S
L
V
E
Y
K
-
P
E
L
Q
K
A
M
E
F
V
F
G
-
T
T
F
V
C
D
N
M
D
N
A
K
K
V
A
F
D
K
R
I
M
T
R
T
V
T
L
G
G
D
V
F
D
P
H
G
T
L
S
G
G
A
-
R
S
Q
A
A
S
I
L
T
K
F
Q
E
L
K
D
V
Q
D
E
L
R
I
K
E
N
E
L
R
A
L
E
E
E
L
A
G
L
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
64.52
45%
-125
- C1 -
1XEX
1
?
B:
[8-155]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
M
R
T
F
E
A
I
S
R
N
F
S
E
I
F
A
K
L
-
S
P
G
G
S
A
R
L
I
L
E
N
---
P
F
S
G
G
L
E
I
E
A
K
P
A
G
K
D
V
K
R
I
E
A
M
S
G
G
E
K
A
L
T
A
L
A
F
V
F
A
I
Q
K
F
K
P
A
P
F
Y
L
F
D
Q
I
D
A
H
L
D
D
A
N
V
K
R
V
A
D
L
I
K
E
S
-
S
K
E
S
Q
F
I
V
I
T
L
R
D
V
M
M
A
N
A
D
K
I
I
G
V
S
-
M
R
D
-
G
V
S
K
V
V
S
L
S
L
E
K
A
-----
95
HHSearch
64.48
32%
-154
- C3 -
4RSJ
-
SMC_PYRFU
A:
[519-694]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
G
G
I
Y
G
T
L
A
E
L
I
K
V
K
D
E
A
Y
A
L
A
I
E
V
A
L
G
N
R
A
D
N
V
V
V
E
D
E
L
V
A
E
K
A
I
K
Y
--
L
K
E
H
K
L
G
R
L
T
F
L
P
L
---
N
K
I
K
P
K
H
V
D
----------
S
S
V
G
L
-----
P
A
V
D
V
I
E
Y
D
-
Q
K
I
E
N
A
V
K
F
A
L
G
-
D
T
V
I
V
N
S
M
E
E
A
R
P
H
I
G
----
K
V
R
M
V
T
I
E
G
E
L
Y
E
R
S
G
A
I
T
G
G
H
F
---------
L
A
V
D
T
T
K
L
R
E
K
V
E
S
L
R
R
R
K
E
A
L
E
G
E
L
N
S
L
K
I
E
L
R
S
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
64.40
32%
-153
- C3 -
1GXL
-
?
A:
[486-663]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
M
I
E
R
D
M
R
E
Y
R
G
F
S
R
A
V
R
A
V
F
E
E
K
E
R
F
P
G
L
V
D
V
V
S
N
L
I
E
V
-
D
E
K
Y
S
L
A
V
S
V
L
L
G
G
T
A
Q
N
I
V
V
R
N
V
D
T
A
K
A
I
V
E
F
--
L
K
Q
N
E
A
G
R
V
T
I
L
P
L
---
D
L
I
-
D
G
S
F
N
R
I
S
G
L
E
N
E
R
--
G
F
V
G
-----
Y
A
V
D
L
V
K
F
P
-
S
D
L
E
V
L
G
G
F
L
F
G
-
N
S
V
V
V
E
T
L
D
D
A
I
R
M
K
K
K
Y
R
L
N
T
R
I
A
T
L
D
G
E
L
I
S
G
R
G
A
I
T
G
G
R
E
E
R
S
S
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
64.36
31%
-160
- C3 -
1GXK
-
?
A:
[501-658]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
A
V
R
A
V
F
E
E
K
E
R
F
P
G
L
V
D
V
V
S
N
L
I
E
V
-
D
E
K
Y
S
L
A
V
S
V
L
L
G
G
T
A
Q
N
I
V
V
R
N
V
D
T
A
K
A
I
V
E
F
--
L
K
Q
N
E
A
G
R
V
T
I
L
P
L
---
D
L
I
D
G
S
F
N
R
I
S
G
L
E
N
---
E
R
G
F
V
G
-----
Y
A
V
D
L
V
K
F
P
-
S
D
L
E
V
L
G
G
F
L
F
G
-
N
S
V
V
V
E
T
L
D
D
A
I
R
M
K
K
K
Y
R
L
N
T
R
I
A
T
L
D
G
E
L
I
S
G
R
G
A
I
T
G
G
R
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
63.77
26%
-158
- C3 -
3L51
2
B:
[11-158]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
S
G
R
I
P
G
I
Y
G
R
L
G
D
L
G
A
I
-
D
E
K
Y
D
I
A
I
S
S
C
C
H
A
-
L
D
Y
I
V
V
D
S
I
D
T
A
Q
E
C
V
N
F
--
L
K
K
H
N
I
G
I
A
T
F
I
G
L
DKM
T
V
W
A
K
K
M
S
K
I
Q
T
P
E
N
T
P
R
L
F
D
L
V
K
-----
V
K
N
E
E
I
-------
R
Q
A
F
Y
F
A
L
R
-
D
T
L
V
A
N
N
L
D
Q
A
T
R
V
A
Y
Q
R
D
R
R
W
R
V
V
T
L
Q
G
Q
I
I
E
Q
S
G
T
M
S
G
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
63.75
46%
-124
- C1 -
1XEW
-
?
Y:
[1013-1160]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
M
R
T
F
E
A
I
S
R
N
F
S
E
I
F
A
K
L
-
S
P
G
G
S
A
R
L
I
L
E
N
P
E
D
P
F
S
G
G
L
E
I
E
A
K
P
A
G
K
D
V
K
R
I
E
A
M
S
G
G
E
K
A
L
T
A
L
A
F
V
F
A
I
Q
K
F
K
P
A
P
F
Y
L
F
D
E
I
D
A
H
L
D
D
A
N
V
K
R
V
A
D
L
I
K
E
S
-
S
K
E
S
Q
F
I
V
I
T
L
R
D
V
M
M
A
N
A
D
K
I
I
G
V
S
-
M
---
G
V
S
K
V
V
S
L
S
L
E
K
A
-----
107
HHSearch
63.11
31%
-168
- C3 -
1GXJ
-
?
A:
[513-657]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
P
G
L
V
D
V
V
S
N
L
I
E
V
-
D
E
K
Y
S
L
A
V
S
V
L
L
G
G
T
A
Q
N
I
V
V
R
N
V
D
T
A
K
A
I
V
E
F
--
L
K
Q
N
E
A
G
R
V
T
I
L
P
L
---
D
L
I
D
G
S
F
N
R
I
---
S
G
L
E
N
E
R
G
F
V
G
-----
Y
A
V
D
L
V
K
F
P
-
S
D
L
E
V
L
G
G
F
L
F
G
-
N
S
V
V
V
E
T
L
D
D
A
I
R
M
K
K
K
Y
R
L
N
T
R
I
A
T
L
D
G
E
L
I
S
G
R
G
A
I
T
G
G
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
110
HHSearch
62.96
31%
-175
- C3 -
1GXL
-
?
A:
[513-657]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
P
G
L
V
D
V
V
S
N
L
I
E
V
-
D
E
K
Y
S
L
A
V
S
V
L
L
G
G
T
A
Q
N
I
V
V
R
N
V
D
T
A
K
A
I
V
E
F
--
L
K
Q
N
E
A
G
R
V
T
I
L
P
L
---
D
L
I
D
G
S
F
N
R
I
---
S
G
L
E
N
E
R
G
F
V
G
-----
Y
A
V
D
L
V
K
F
P
-
S
D
L
E
V
L
G
G
F
L
F
G
-
N
S
V
V
V
E
T
L
D
D
A
I
R
M
K
K
K
Y
R
L
N
T
R
I
A
T
L
D
G
E
L
I
S
G
R
G
A
I
T
G
G
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
62.83
43%
-112
- C1 -
4I99
2
?
A:
[190-338]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
M
R
T
F
E
A
I
S
R
N
F
S
E
I
F
A
K
L
-
S
P
G
G
S
A
R
L
I
L
E
N
P
E
D
P
F
S
G
G
L
E
I
E
A
K
P
A
G
K
D
V
K
R
I
E
A
M
S
G
G
E
K
A
L
T
A
L
A
F
V
F
A
I
Q
K
F
K
P
A
P
F
Y
L
F
D
E
I
D
A
H
L
D
D
A
N
V
K
R
V
A
D
L
I
K
E
S
-
S
K
E
S
Q
F
I
V
I
T
L
R
D
V
M
M
A
N
A
D
K
I
I
G
V
S
-
M
R
D
-
G
V
S
K
V
V
S
L
S
L
E
K
A
M
----
22
PsiBlast_CBE
62.22
38%
-126
- C1 -
1W1W
2
D:
[269-428]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
K
T
F
D
Y
V
S
D
H
L
D
A
I
Y
R
E
L
T---
G
N
A
S
L
T
I
E
D
E
D
E
P
F
N
A
G
I
K
Y
H
A
T
P
P
L
K
R
F
K
D
M
E
Y
L
S
G
G
E
K
T
V
A
A
L
A
L
L
F
A
I
N
S
Y
Q
P
S
P
F
F
V
L
D
E
V
D
A
A
L
D
I
T
N
V
Q
R
I
A
A
Y
I
R
R
H
R
N
P
D
L
Q
F
I
V
I
S
L
K
N
T
M
F
E
K
S
D
A
L
V
G
V
Y
R
Q
Q
Q
E
N
S
S
K
I
I
T
L
D
L
S
N
Y
-----
10
PsiBlast_PDB
61.46
33%
-153
- C- -
3NWC
-
SMC_PYRFU
A:
[519-658]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
G
G
I
Y
G
T
L
A
E
L
I
K
V
K
D
E
A
Y
A
L
A
I
E
V
A
L
G
N
R
A
D
N
V
V
V
E
D
E
L
V
A
E
K
A
I
K
Y
--
L
K
E
H
K
L
G
R
L
T
F
L
P
L
---
N
K
I
K
P
K
H
V
D
----------
S
S
V
G
L
-----
P
A
V
D
V
I
E
Y
D
-
Q
K
I
E
N
A
V
K
F
A
L
G
D
T
V
I
V
N
S
M
E
E
A
R
P
H
I
G
K
V
-----
R
M
V
T
I
E
G
E
L
Y
E
R
S
G
A
I
T
G
G
H
F
R
A
R
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------