@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu15950: (2016-06-25 )
MSFFKKLKEKITKQTDSVSEKFKDGLEKTRNSFQNKVNDLVSRYRKVDEDFFEELEEVLISADVGFTTVMELIDELKKEVKRRNIQDPKEVQSVISEKLVEIYNSGDEQISELNIQDGRLNVILLVGVNGVGKTTTIGKLAHKMKQEGKSVVLAAGDTFRAGAIEQLEVWGERTGVPVIKQTAGSDPAAVIYDAVHAAKARNADVLICDTAGRLQNKVNLMKELEKVKRVIEREVPEAPHEVLLALDATTGQNAMAQAKEFSKATNVTGIALTKLDGTAKGGIVLAIRNELHIPVKLVGLGEKVDDLQEFDPESYVYGLFSDLVEKADD
Atome Classification :
(53 SA)
.........10........20........30........40..---.-.....50-.---....----....60........70.......----.80----.----..----.--------..---.-.90........100.....--.--.110-.--..-----...-----.-------..120.......130.......140....-...150........160.......170---.---....-..-180.-.-.....190.....-..200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.---......320.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
S
F
F
K
K
L
K
E
K
I
T
KQ
T
D
S
V
S
E
K
F
K
D
G
L
E
K
T
R
N
S
F
Q
N
K
V
N
D
L
V
S
R
---
Y
-
R
KV
D
E
D
--
F
---
F
E
E
L
----
E
E
V
L
I
SAD
V
G
F
T
T
V
M
E
L
I
D
E
L
K
K
----
E
V
K
----R----RN----I--------Q
D
---
P
-
K
E
V
Q
S
V
I
S
E
K
L
V
E
I
Y
NSGD--E--
Q
I
---
S
--
E
L
-----NIQ-----D-------G
R
L
N
V
I
L
L
V
GVNGVGKT
T
T
I
G
K
L
A
H
K
M
K
Q-EG
K
S
-
V
V
L
AAGDTFRAG
A
I
E
Q
L
E
V
W
GE---R---TGV
P
-
V
I
-KQTA-G-SD
P
A
A
V
I
Y
D
A
V
H
A
-AKARNA
D
V
L
I
CDT
A
G
R
L
Q
N
K
V
N
L
M
K
E
L
E
K
V
K
R
V
I
E
R
EVPEA
P
H
E
V
L
L
A
L
DATTG
Q
N
A
M
A
Q
A
K
E
F
S
KATN
V
T
G
I
A
L
T
KLDGTAKG
G
I
V
L
A
IRNELH
I
P
V
K
L
V
GLGEK
V
D
D
L
Q
EFDP
E
---
S
Y
V
Y
G
L
F
S
D
L
V
E
KADD
94
HHSearch
82.27
54%
-108
- C8 -
1VMA
1
?
A:
[13-306]
---------------
M
G
L
F
D
F
L
K
K
G
L
Q
K
T
K
E
T
F
F
G
R
V
V
K
L
L
K
G
-----
K
K
L
D
D
E
--
T
---
R
E
E
L
----
E
E
L
L
I
Q
A
D
V
G
V
E
T
T
E
Y
I
L
E
R
L
E
E
----
K
D
G
--------------------------------
D
A
L
E
S
L
K
E
I
I
L
E
I
L
N
F
D
T
-------------
K
L
-----
N
V
P
-----
P
-------
E
P
P
F
V
I
M
V
V
G
V
N
G
T
G
K
T
T
S
C
G
K
L
A
K
M
F
V
D
-
E
G
K
S
-
V
V
L
A
A
A
D
T
F
R
A
A
A
I
E
Q
L
K
I
W
G
E
---
R
---
V
G
A
T
-
V
I
-
S
H
S
E
-
G
-
A
D
P
A
A
V
A
F
D
A
V
A
H
-
A
L
A
R
N
K
D
V
V
I
I
D
T
A
G
R
L
H
T
K
K
N
L
M
E
E
L
R
K
V
H
R
V
V
K
K
K
I
P
D
A
P
H
E
T
L
L
V
I
D
A
T
T
G
Q
N
G
L
V
Q
A
K
I
F
K
E
A
V
N
V
T
G
I
I
L
T
K
L
D
G
T
A
K
G
G
I
T
L
A
I
A
R
E
L
G
I
P
I
K
F
I
G
V
G
E
K
A
E
D
L
R
P
F
D
P
E
---
A
F
V
E
V
L
L
S
E
-------
9
PsiBlast_PDB
81.79
53%
-110
- C8 -
1VMA
1
?
A:
[19-306]
---------------------
L
K
K
G
L
Q
K
T
K
E
T
F
F
G
R
V
V
K
L
L
-
K
---
G
-
K
K
L
D
D
E
--
T
---
R
E
E
L
----
E
E
L
L
I
Q
A
D
V
G
V
E
T
T
E
Y
I
L
E
R
L
E
E
-------------------------------
K
D
---
G
-
D
A
L
E
S
-
L
K
E
I
I
L
E
I
L
N
F
D
-----------
T
--
K
L
-----
N
V
P
-----
P
-------
E
P
P
F
V
I
M
V
V
G
V
N
G
T
G
K
T
T
S
C
G
K
L
A
K
M
F
V
D
-
E
G
K
S
-
V
V
L
A
A
A
D
T
F
R
A
A
A
I
E
Q
L
K
I
W
G
E
---
R
---
V
G
A
T
-
V
I
-
S
H
S
E
-
G
-
A
D
P
A
A
V
A
F
D
A
V
A
H
-
A
L
A
R
N
K
D
V
V
I
I
D
T
A
G
R
L
H
T
K
K
N
L
M
E
E
L
R
K
V
H
R
V
V
K
K
K
I
P
D
A
P
H
E
T
L
L
V
I
D
A
T
T
G
Q
N
G
L
V
Q
A
K
I
F
K
E
A
V
N
V
T
G
I
I
L
T
K
L
D
G
T
A
K
G
G
I
T
L
A
I
A
R
E
L
G
I
P
I
K
F
I
G
V
G
E
K
A
E
D
L
R
P
F
D
P
E
---
A
F
V
E
V
L
L
S
E
-------
23
PsiBlast_CBE
81.63
53%
-113
- C8 -
1VMA
1
?
B:
[19-306]
---------------------
L
K
K
G
L
Q
K
T
K
E
T
F
F
G
R
V
V
K
L
L
-
K
---
G
-
K
K
L
D
D
E
--
T
---
R
E
E
L
----
E
E
L
L
I
Q
A
D
V
G
V
E
T
T
E
Y
I
L
E
R
L
E
E
-------------------------------
K
D
---
G
-
D
A
L
E
S
-
L
K
E
I
I
L
E
I
L
N
F
D
-----------
T
--
K
L
-----
N
V
P
-----
P
-------
E
P
P
F
V
I
M
V
V
G
V
N
G
T
G
K
T
T
S
C
G
K
L
A
K
M
F
V
D
-
E
G
K
S
-
V
V
L
A
A
A
D
T
F
R
A
A
A
I
E
Q
L
K
I
W
G
E
---
R
---
V
G
A
T
-
V
I
-
S
H
S
E
-
G
-
A
D
P
A
A
V
A
F
D
A
V
A
H
-
A
L
A
R
N
K
D
V
V
I
I
D
T
A
G
R
L
H
T
K
K
N
L
M
E
E
L
R
K
V
H
R
V
V
K
K
K
I
P
D
A
P
H
E
T
L
L
V
I
D
A
T
T
G
Q
N
G
L
V
Q
A
K
I
F
K
E
A
V
N
V
T
G
I
I
L
T
K
L
D
G
T
A
K
G
G
I
T
L
A
I
A
R
E
L
G
I
P
I
K
F
I
G
V
G
E
K
A
E
D
L
R
P
F
D
P
E
---
A
F
V
E
V
L
L
S
E
-------
103
HHSearch
81.21
45%
-120
- C8 -
1ZU4
1
FTSY_MYCMS
A:
[10-314]
------------------------
A
M
L
K
S
A
F
N
F
S
K
D
I
K
K
L
S
K
K
---
Y
-
K
Q
A
D
D
E
--
F
---
F
E
E
L
----
E
D
V
L
I
Q
T
D
M
G
M
K
M
V
L
K
V
S
N
L
V
R
K
----
K
T
K
----
R
----
D
--------------
T
S
---
F
-
E
N
I
K
D
A
L
V
E
S
L
Y
Q
A
Y
T
D
N
D
--
W
--------Y-
R
I
-----
D
F
K
-----
E
-------
N
R
L
N
I
F
M
L
V
G
V
N
G
T
G
K
T
T
S
L
A
K
M
A
N
Y
Y
A
E
-
L
G
Y
K
-
V
L
I
A
A
A
D
T
F
R
A
G
A
T
Q
Q
L
E
E
W
I
K
---
T
RLN
N
K
V
D
-
L
V
-
K
A
N
K
-
L
N
A
D
P
A
S
V
V
F
D
A
I
K
K
-
A
K
E
Q
N
Y
D
L
L
L
I
D
T
A
G
R
L
Q
N
K
T
N
L
M
A
E
L
E
K
M
N
K
I
I
Q
Q
V
E
K
S
A
P
H
E
V
L
L
V
I
D
A
T
T
G
Q
N
G
V
I
Q
A
E
E
F
S
K
V
A
D
V
S
G
I
I
L
T
K
M
D
S
T
S
K
G
G
I
G
L
A
I
K
E
L
L
N
I
P
I
K
M
I
G
V
G
E
K
V
D
D
L
L
A
F
D
I
D
---
Q
Y
I
V
H
L
S
S
G
F
M
Q
----
3
PsiBlast_PDB
80.78
50%
-119
- C8 -
2YHS
5
FTSY_ECOLI
A:
[188-494]
--------
E
K
P
T
K
--
E
G
F
F
A
R
L
K
R
S
L
L
K
T
K
E
N
L
G
S
G
F
I
S
L
F
-
R
---
G
-
K
K
I
D
D
D
--
L
---
F
E
E
L
----
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
----
G
A
S
----
R
----
K
Q
----
L
--------
R
D
---
A
-
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
--
E
--
P
--------
L
-----
N
V
E
-----
G
-------
K
A
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
Q
-
Q
G
K
S
-
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
---
R
---
N
N
I
P
-
V
I
-
A
Q
H
T
-
G
-
A
D
S
A
S
V
I
F
D
A
I
Q
A
-
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
---
D
F
I
E
A
L
F
A
--------
6
PsiBlast_PDB
80.76
53%
-119
- C8 -
4C7O
4
FTSY_ECOLI
B:
[5-275]
---------------------------------------------------
D
D
D
--
L
---
F
E
E
L
----
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
----
G
A
S
----
R
----
K
Q
----
L
--------
R
D
---
A
-
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
--
E
----------
P
L
-----
N
V
E
-----
G
-------
K
A
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
Q
-
Q
G
K
S
-
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
---
R
---
N
N
I
P
-
V
I
-
A
Q
H
T
-
G
-
A
D
S
A
S
V
I
F
D
A
I
Q
A
-
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
---
D
F
I
E
A
L
F
A
--------
22
PsiBlast_CBE
80.48
53%
-121
- C8 -
4C7O
5
FTSY_ECOLI
D:
[2-275]
------------------------------------------------
K
K
I
D
D
D
--
L
---
F
E
E
L
----
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
----
G
A
S
----
R
----
K
Q
----
L
--------
R
D
---
A
-
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
--
E
----------
P
L
-----
N
V
E
-----
G
-------
K
A
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
Q
-
Q
G
K
S
-
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
---
R
---
N
N
I
P
-
V
I
-
A
Q
H
T
-
G
-
A
D
S
A
S
V
I
F
D
A
I
Q
A
-
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
---
D
F
I
E
A
L
F
A
--------
4
PsiBlast_PDB
80.41
53%
-129
- C8 -
1FTS
-
FTSY_ECOLI
A:
[219-494]
------------------------------------------
R
---
G
-
K
K
I
D
D
D
--
L
---
F
E
E
L
----
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
----
G
A
S
----
R
----
K
Q
----
L
--------
R
D
---
A
-
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
--
E
----------
P
L
-----
N
V
E
-----
G
-------
K
A
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
Q
-
Q
G
K
S
-
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
---
R
---
N
N
I
P
-
V
I
-
A
Q
H
T
-
G
-
A
D
S
A
S
V
I
F
D
A
I
Q
A
-
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
---
D
F
I
E
A
L
F
A
--------
89
HHSearch
80.27
40%
-126
- C8 -
3B9Q
1
CFTSY_ARATH
A:
[2-302]
--------------------
K
V
F
S
G
F
S
K
T
R
E
N
L
A
V
-
I
D
E
L
L
L
F
---
W
N
L
A
E
T
D
R
--
V
---
L
D
E
L
----
E
E
A
L
L
V
S
D
F
G
P
K
I
T
V
R
I
V
E
R
L
R
E
----
D
I
M
----
S
----
G
K
----
L
--------
K
S
---
G
-
S
E
I
K
D
A
L
K
E
S
V
L
E
M
L
A
K
----
S
---
K
---
T
--
E
L
-----
Q
L
G
-----
F
-------
R
K
P
A
V
I
M
I
V
G
V
N
G
G
G
K
T
T
S
L
G
K
L
A
H
R
L
K
N
-
E
G
T
K
-
V
L
M
A
A
G
D
T
F
R
A
A
A
S
D
Q
L
E
I
W
A
E
---
R
---
T
G
C
E
-
I
V
-
V
A
E
---K
A
K
A
A
T
V
L
S
K
A
V
K
R
-
G
K
E
E
G
Y
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
S
L
M
E
E
L
I
A
C
K
K
A
V
G
K
I
V
S
G
A
P
N
E
I
L
L
V
L
D
G
N
T
G
L
N
M
L
P
Q
A
R
E
F
N
E
V
V
G
I
T
G
L
I
L
T
K
L
D
G
S
A
R
G
G
C
V
V
S
V
V
E
E
L
G
I
P
V
K
F
I
G
V
G
E
A
V
E
D
L
Q
P
F
D
P
E
---
A
F
V
N
A
I
F
S
--------
88
HHSearch
80.21
50%
-120
- C8 -
2YHS
5
FTSY_ECOLI
A:
[193-494]
---------------
E
G
F
F
A
R
L
K
R
S
L
L
K
T
K
E
N
L
G
S
G
F
I
S
L
F
R
G
-----
K
K
I
D
D
D
--
L
---
F
E
E
L
----
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
----
G
A
S
----
R
----
K
Q
----
L
--------
R
D
---
A
-
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
----------
E
--
P
L
-----
N
V
E
-----
G
-------
K
A
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
Q
-
Q
G
K
S
-
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
---
R
---
N
N
I
P
-
V
I
-
A
Q
H
T
-
G
-
A
D
S
A
S
V
I
F
D
A
I
Q
A
-
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
---
D
F
I
E
A
L
F
A
--------
2
PsiBlast_PDB
80.07
50%
-116
- C8 -
2QY9
-
FTSY_ECOLI
A:
[198-494]
--------------------
R
L
K
R
S
L
L
K
T
K
E
N
L
G
S
G
F
I
S
L
F
-
R
---
G
-
K
K
I
D
D
D
--
L
---
F
E
E
L
----
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
----
G
A
S
----
R
----
K
Q
----
L
--------
R
D
---
A
-
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
--
E
----------
P
L
-----
N
V
E
-----
G
-------
K
A
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
Q
-
Q
G
K
S
-
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
---
R
---
N
N
I
P
-
V
I
-
A
Q
H
T
-
G
-
A
D
S
A
S
V
I
F
D
A
I
Q
A
-
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
---
D
F
I
E
A
L
F
A
--------
12
PsiBlast_PDB
80.05
40%
-121
- C8 -
3B9Q
1
CFTSY_ARATH
A:
[1-302]
-------------------
E
K
V
F
S
G
F
S
K
T
R
E
N
L
A
-
V
I
D
E
L
L
L
F
---
W
-
N
L
A
E
T
D
R
-
V
---
L
D
E
L
----
E
E
A
L
L
V
S
D
F
G
P
K
I
T
V
R
I
V
E
R
L
R
E
----
D
I
M
----
S
----
G
K
----
L
--------
K
S
---
G
-
S
E
I
K
D
A
L
K
E
S
V
L
E
M
L
A
K
----
S
--
K
----
T
--
E
L
-----
Q
L
G
-----
F
-------
R
K
P
A
V
I
M
I
V
G
V
N
G
G
G
K
T
T
S
L
G
K
L
A
H
R
L
K
N
-
E
G
T
K
-
V
L
M
A
A
G
D
T
F
R
A
A
A
S
D
Q
L
E
I
W
A
E
---
R
---
T
G
C
E
I
V
V
-
A
E
---
K
-
A
K
A
A
T
V
L
S
K
A
V
K
R
-
G
K
E
E
G
Y
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
S
L
M
E
E
L
I
A
C
K
K
A
V
G
K
I
V
S
G
A
P
N
E
I
L
L
V
L
D
G
N
T
G
L
N
M
L
P
Q
A
R
E
F
N
E
V
V
G
I
T
G
L
I
L
T
K
L
D
G
S
A
R
G
G
C
V
V
S
V
V
E
E
L
G
I
P
V
K
F
I
G
V
G
E
A
V
E
D
L
Q
P
F
D
P
E
---
A
F
V
N
A
I
F
S
--------
7
PsiBlast_PDB
79.97
45%
-118
- C8 -
1ZU4
1
FTSY_MYCMS
A:
[13-314]
---------------------------
K
S
A
F
N
F
S
K
D
I
K
K
L
S
K
K
---
Y
-
K
Q
A
D
D
E
--
F
---
F
E
E
L
----
E
D
V
L
I
Q
T
D
M
G
M
K
M
V
L
K
V
S
N
L
V
R
K
----
K
T
K
----
R
DTS
F
E
N
----
I
--------
K
D
---
A
-------
L
V
E
S
L
Y
Q
A
Y
T
D
N
D
W---------
Y
--
R
I
-----
D
F
K
-----
E
-------
N
R
L
N
I
F
M
L
V
G
V
N
G
T
G
K
T
T
S
L
A
K
M
A
N
Y
Y
A
E
-
L
G
Y
K
-
V
L
I
A
A
A
D
T
F
R
A
G
A
T
Q
Q
L
E
E
W
I
K
T
RL
N
---
N
K
V
D
-
L
V
-
K
A
N
K
L
N
-
A
D
P
A
S
V
V
F
D
A
I
K
K
-
A
K
E
Q
N
Y
D
L
L
L
I
D
T
A
G
R
L
Q
N
K
T
N
L
M
A
E
L
E
K
M
N
K
I
I
Q
Q
V
E
K
S
A
P
H
E
V
L
L
V
I
D
A
T
T
G
Q
N
G
V
I
Q
A
E
E
F
S
K
V
A
D
V
S
G
I
I
L
T
K
M
D
S
T
S
K
G
G
I
G
L
A
I
K
E
L
L
N
I
P
I
K
M
I
G
V
G
E
K
V
D
D
L
L
A
F
D
I
D
---
Q
Y
I
V
H
L
S
S
G
F
M
Q
----
1
PsiBlast_PDB
79.71
50%
-120
- C8 -
2XXA
3
FTSY_ECOLI
B:
[20-299]
-------------------------------------
I
S
L
F
-
R
---
G
-
K
K
I
D
D
D
--
L
---
F
E
E
L
----
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
----
G
A
S
----
R
----
K
Q
----
L
--------
R
D
---
A
-
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
--
E
----------
P
L
-----
N
V
E
-----
G
-------
K
A
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
Q
-
Q
G
K
S
-
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
---
R
---
N
N
I
P
-
V
I
-
A
Q
H
T
-
G
-
A
D
S
A
S
V
I
F
D
A
I
Q
A
-
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
---
D
F
I
E
A
L
F
A
--------
5
PsiBlast_PDB
79.65
53%
-129
- C8 -
3ZN8
-
FTSY_ECOLI
D:
[19-294]
------------------------------------------
R
---
G
-
K
K
I
D
D
D
--
L
---
F
E
E
L
----
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
----
G
A
S
----
R
----
K
Q
----
L
--------
R
D
---
A
-
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
--
E
----------
P
L
-----
N
V
E
-----
G
-------
K
A
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
Q
-
Q
G
K
S
-
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
---
R
---
N
N
I
P
-
V
I
-
A
Q
H
T
-
G
-
A
D
S
A
S
V
I
F
D
A
I
Q
A
-
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
---
D
F
I
E
A
L
F
A
--------
8
PsiBlast_PDB
79.64
45%
-116
- C8 -
1ZU5
-
FTSY_MYCMS
A:
[104-404]
---------------------------
K
S
A
F
N
F
S
K
D
I
K
K
L
S
K
K
---
Y
-
K
Q
A
D
D
E
--
F
---
F
E
E
L
----
E
D
V
L
I
Q
T
D
M
G
M
K
M
V
L
K
V
S
N
L
V
R
K
----
K
T
K
----
R
DTS
F
E
N
----
I
--------
K
D
---
A
-------
L
V
E
S
L
Y
Q
A
Y
T
D
N
D
WT
N
--
K
K
---
Y
--
R
I
-----
D
F
K
-----
E
-------
N
R
L
N
I
F
M
L
V
G
V
N
G
T
G
K
T
T
S
L
A
K
M
A
N
Y
Y
A
E
-
L
G
Y
K
-
V
L
I
A
A
A
D
T
F
R
A
G
A
T
Q
Q
L
E
E
W
I
K
TRL
N
---
N
K
V
D
-
L
V
-
K
A
N
K
L
N
-
A
D
P
A
S
V
V
F
D
A
I
K
K
-
A
K
E
Q
N
Y
D
L
L
L
I
D
T
A
G
R
L
Q
N
K
T
N
L
M
A
E
L
E
K
M
N
K
I
I
Q
Q
V
E
K
S
A
P
H
E
V
L
L
V
I
D
A
T
T
G
Q
N
G
V
I
Q
A
E
E
F
S
K
V
A
D
V
S
G
I
I
L
T
K
M
D
S
T
S
K
G
G
I
G
L
A
I
K
E
L
L
N
I
P
I
K
M
I
G
V
G
E
K
V
D
D
L
L
A
F
D
I
D
---
Q
Y
I
V
H
L
S
S
G
F
M
-----
21
PsiBlast_CBE
79.62
50%
-120
- C8 -
2XXA
3
FTSY_ECOLI
D:
[20-299]
-------------------------------------
I
S
L
F
-
R
---
G
-
K
K
I
D
D
D
--
L
---
F
E
E
L
----
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
----
G
A
S
----
R
----
K
Q
----
L
--------
R
D
---
A
-
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
--
E
----------
P
L
-----
N
V
E
-----
G
-------
K
A
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
Q
-
Q
G
K
S
-
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
---
R
---
N
N
I
P
-
V
I
-
A
Q
H
T
-
G
-
A
D
S
A
S
V
I
F
D
A
I
Q
A
-
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
---
D
F
I
E
A
L
F
A
--------
87
HHSearch
77.43
40%
-122
- C8 -
2OG2
2
CFTSY_ARATH
A:
[55-358]
----------------
S
D
V
E
K
V
F
S
G
F
S
K
T
R
E
N
L
A
V
-
I
D
E
L
L
L
F
---
W
N
L
A
E
T
D
R
--
V
---
L
D
E
L
----
E
E
A
L
L
V
S
D
F
G
P
K
I
T
V
R
I
V
E
R
L
R
E
----
D
I
M
----
S
----
G
K
----
L
--------
K
S
---
G
-
S
E
I
K
D
A
L
K
E
S
V
L
E
M
L
A
K
K
-----------
T
--
E
L
-----
Q
L
G
-----
F
-------
R
K
P
A
V
I
M
I
V
G
V
N
G
G
G
K
T
T
S
L
G
K
L
A
H
R
L
K
N
-
E
G
T
K
-
V
L
M
A
A
G
D
T
F
R
A
A
A
S
D
Q
L
E
I
W
A
E
---
R
---
T
G
C
E
-
I
V
-
V
A
E
G
D
K
-
A
K
A
A
T
V
L
S
K
A
V
K
R
-
G
K
E
E
G
Y
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
S
L
M
E
E
L
I
A
C
K
K
A
V
G
K
I
V
S
G
A
P
N
E
I
L
L
V
L
D
G
N
T
G
L
N
M
L
P
Q
A
R
E
F
N
E
V
V
G
I
T
G
L
I
L
T
K
L
D
G
S
A
R
G
G
C
V
V
S
V
V
E
E
L
G
I
P
V
K
F
I
G
V
G
E
A
V
E
D
L
Q
P
F
D
P
E
---
A
F
V
N
A
I
F
---------
11
PsiBlast_PDB
76.64
40%
-118
- C8 -
2OG2
2
CFTSY_ARATH
A:
[55-359]
----------------
S
D
V
E
K
V
F
S
G
F
S
K
T
R
E
N
L
A
-
V
I
D
E
L
L
L
F
---
W
-
N
L
A
E
T
D
R
-
V
---
L
D
E
L
----
E
E
A
L
L
V
S
D
F
G
P
K
I
T
V
R
I
V
E
R
L
R
E
----
D
I
M
----
S
----
G
K
----
L
--------
K
S
---
G
-
S
E
I
K
D
A
L
K
E
S
V
L
E
M
L
A
K
K
-----------
T
--
E
L
-----
Q
L
G
-----
F
-------
R
K
P
A
V
I
M
I
V
G
V
N
G
G
G
K
T
T
S
L
G
K
L
A
H
R
L
K
N
-
E
G
T
K
-
V
L
M
A
A
G
D
T
F
R
A
A
A
S
D
Q
L
E
I
W
A
E
---
R
---
T
G
C
E
I
V
V
-
A
E
G
D
-
K
-
A
K
A
A
T
V
L
S
K
A
V
K
R
-
G
K
E
E
G
Y
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
S
L
M
E
E
L
I
A
C
K
K
A
V
G
K
I
V
S
G
A
P
N
E
I
L
L
V
L
D
G
N
T
G
L
N
M
L
P
Q
A
R
E
F
N
E
V
V
G
I
T
G
L
I
L
T
K
L
D
G
S
A
R
G
G
C
V
V
S
V
V
E
E
L
G
I
P
V
K
F
I
G
V
G
E
A
V
E
D
L
Q
P
F
D
P
E
---
A
F
V
N
A
I
F
S
--------
10
PsiBlast_PDB
75.72
44%
-125
- C8 -
4AK9
-
?
A:
[87-382]
------------------------
G
F
S
K
T
R
E
N
L
--
A
V
V
D
E
L
L
T
---
Y
-
W
N
L
D
E
S
E
S
I
---
L
D
E
L
----
E
E
V
L
L
V
S
D
F
G
P
K
T
A
L
K
I
V
D
T
I
R
K
----
D
I
L
----
A
----
G
R
----
L
--------
K
S
---
G
-
P
Q
I
K
E
A
L
K
K
N
I
F
K
L
L
T
-----
E
--
R
V
---
T
TT
E
L
-----
Q
L
G
-----
N
-------
S
R
P
A
V
L
M
I
V
G
V
N
G
G
G
K
T
T
T
L
G
K
L
A
N
R
F
K
K
-
E
G
V
K
-
V
L
M
A
A
G
D
T
--
A
A
A
G
E
Q
L
E
V
W
A
Q
---
R
---
T
G
S
E
-
I
V
M
A
------
P
R
P
A
A
V
L
S
Q
A
V
R
R
-
A
V
E
E
D
F
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
N
L
M
E
E
L
R
G
C
K
R
A
V
S
K
A
L
S
S
A
P
N
E
V
L
L
V
L
D
G
T
T
G
L
N
M
L
A
Q
A
R
E
F
N
Q
V
I
G
V
T
G
F
I
L
T
K
L
D
G
T
A
R
G
G
C
V
V
S
V
V
D
E
L
S
I
P
V
K
F
V
G
V
G
E
G
I
D
D
L
Q
P
F
D
A
Q
---
S
F
V
D
A
L
F
---------
101
HHSearch
73.84
47%
-118
- C8 -
1RJ9
3
FTSY_THEAQ
A:
[27-303]
--------------------------------------------------
N
L
E
E
--
V
---
L
E
E
L
----
E
M
A
L
L
A
A
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
A
----
S
G
R
-------------------------------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
D
E
R
R
A
--
T
L
---
R
--
K
L
-----
G
F
N
-----
P
Q
KPKPVE
P
K
G
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
N
-
L
G
K
K
-
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
---
R
---
L
S
I
P
-
V
I
-
Q
G
P
E
-
G
-
T
D
S
A
A
L
A
Y
D
A
V
Q
A
-
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
---
A
F
V
E
A
L
L
E
--------
30
PsiBlast_CBE
70.77
47%
-110
- C8 -
1RJ9
3
FTSY_THEAQ
A:
[43-303]
---------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
A
----
S
G
R
-------------------------------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
-
D
--
E
--
R
R
---
A
--
T
L
R
K
L
G
F
N
P
Q
KPKPV
E
-------
P
K
G
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
N
-
L
G
K
K
-
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
---
R
---
L
S
I
P
-
V
I
-
Q
G
P
E
-
G
-
T
D
S
A
A
L
A
Y
D
A
V
Q
A
-
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
---
A
F
V
E
A
L
L
E
--------
20
PsiBlast_PDB
70.77
48%
-121
- C8 -
2IYL
3
FTSY_THEAQ
D:
[23-284]
---------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
A
----
S
G
R
-------------------------------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
-
D
----------
A
--
T
L
RKLGF
N
P
Q
KPV--
E
-------
P
K
G
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
N
-
L
G
K
K
-
V
M
F
C
A
G
D
T
------
T
Q
L
S
E
W
G
K
---
R
---
L
S
I
P
-
V
I
-
Q
G
P
E
-
G
-
T
D
P
A
A
L
A
Y
D
A
V
Q
A
-
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
--
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
---
A
F
V
E
A
L
L
E
D
-------
18
PsiBlast_PDB
70.19
48%
-112
- C8 -
2J7P
7
FTSY_THEAQ
D:
[22-282]
---------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
A
----
S
G
R
-------------------------------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
-------------------------KPV--
E
-------
P
K
G
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
N
-
L
G
K
K
-
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
---
R
---
L
S
I
P
-
V
I
-
Q
G
P
E
-
G
-
T
D
P
A
A
L
A
Y
D
A
V
Q
A
-
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
---
A
F
V
E
A
L
L
E
--------
96
HHSearch
69.82
43%
-124
- C8 -
3E70
3
?
C:
[52-324]
---------------------------------------------------
V
D
K
--
A
---
L
D
E
L
----
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
----
K
L
V
----
G
----
K
K
----
V
RIG----------
G
-
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
T
S
R
--
R
ID
L
I
---
E
--
E
I
-----
R
K
------
A
-------
E
K
P
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
K
N
-
H
G
F
S
-
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
---
R
---
I
G
V
K
-
V
I
-
K
H
S
Y
-
G
-
A
D
P
A
A
V
A
Y
D
A
I
Q
H
-
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
R
V
T
------
K
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
---
W
F
L
E
R
I
F
G
--------
16
PsiBlast_PDB
69.69
48%
-115
- C8 -
1OKK
8
FTSY_THEAQ
D:
[42-302]
---------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
A
----
S
G
R
-------------------------------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
-------------------------PV---
E
-------
P
K
G
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
N
-
L
G
K
K
-
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
---
R
---
L
S
I
P
-
V
I
-
Q
G
P
E
-
G
-
T
D
P
A
A
L
A
Y
D
A
V
Q
A
-
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
---
A
F
V
E
A
L
L
E
--------
15
PsiBlast_PDB
69.30
48%
-110
- C8 -
2Q9C
8
FTSY_THEAQ
A:
[43-304]
---------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
A
----
S
G
R
-------------------------------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
-
D
--
E
--
R
R
---
A
--
T
L
R
K
L
GF
N
P
Q
KPKPV
E
-------
P
K
G
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
N
-
L
G
K
K
-
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
---
R
---
L
S
I
P
-
V
I
-
Q
G
P
E
-
G
-
T
D
P
A
A
L
A
Y
D
A
V
Q
A
-
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
---
A
F
V
E
A
L
L
E
D
-------
70
PsiBlast_CBE
69.10
33%
-117
- C8 -
4C7O
5
SRP54_ECOLI
C:
[28-297]
----------------------------------------------------
K
D
--
T
---
L
R
E
V
----
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
----
K
A
V
G
H
E
V
N
----
K
S
----
L
--------
T
P
---
G
-
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
-----
E
--
E
N
---
Q
--
T
L
-----
N
L
A
-----
A
-------
Q
P
P
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
-
K
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
---
Q
---
V
G
V
D
-
F
F
-
P
S
D
V
-
G
-
Q
K
P
V
D
I
V
N
A
A
L
K
E
-
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
Q
V
H
A
S
I
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
M
----------
98
HHSearch
69.04
32%
-115
- C8 -
3DM5
10
SRP54_PYRFU
A:
[10-315]
--------------------------------
L
A
N
T
L
K
K
I
A
R
A
SSV
D
-
E
A
L
I
K
E
--
L
---
V
R
D
I
----
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
----
R
A
L
----
E
----
E
K
PPAG
I
--------
S
K
---
K
-
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
T
E
A
--
K
----------
P
I
-----
E
I
K
-------------
E
K
P
T
I
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
Q
K
-
R
G
Y
K
-
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
---
R
---
Y
H
I
E
-
V
F
-
G
N
P
Q
-
E
-
K
D
A
I
K
L
A
K
E
G
V
D
Y
-
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
L
I
E
E
M
K
Q
I
S
N
V
I
------
H
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
---
R
F
V
S
R
L
L
G
L
-------
14
PsiBlast_PDB
68.85
48%
-110
- C8 -
2Q9B
12
FTSY_THEAQ
A:
[43-303]
---------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
A
----
S
G
R
-------------------------------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
-
D
--
E
--
R
R
---
A
--
T
L
R
K
L
GF
N
P
Q
KPKPV
E
-------
P
K
G
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
N
-
L
G
K
K
-
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
---
R
---
L
S
I
P
-
V
I
-
Q
G
P
E
-
G
-
T
D
P
A
A
L
A
Y
D
A
V
Q
A
-
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
---
A
F
V
E
A
L
L
E
--------
34
PsiBlast_CBE
67.83
40%
-122
- C8 -
3DMD
6
?
A:
[56-324]
------------------------------------------------------------
L
D
E
L
----
E
I
D
L
L
E
A
D
V
A
----
L
E
V
V
D
A
L
R
E
----
K
I
K
----
Q
----
K
L
----
V
G
K
K
V
R
IGT
D
K
---
G
-
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
T
S
R
RI
D
--
L
I
---
E
--
E
I
-----
R
K
A
-----
E
--------
K
P
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
K
N
-
H
G
F
S
-
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
---
R
---
I
G
V
K
-
V
I
-
K
H
S
Y
-
G
-
A
D
P
A
A
V
A
Y
D
A
I
Q
H
-
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
R
V
T
K
------
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
---
W
F
L
E
R
I
F
G
--------
32
PsiBlast_CBE
67.62
40%
-126
- C8 -
3DMD
7
?
C:
[56-324]
------------------------------------------------------------
L
D
E
L
----
E
I
D
L
L
E
A
D
V
A
----
L
E
V
V
D
A
L
R
E
----
K
I
K
----
Q
----
K
L
----
V
G
K
K
V
R
IGT
D
K
---
G
-
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
T
S
R
RI
D
--
L
I
---
E
--
E
I
-----
R
K
A
-----
E
--------
K
P
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
K
N
-
H
G
F
S
-
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
---
R
---
I
G
V
K
-
V
I
-
K
H
S
Y
-
G
-
A
D
P
A
A
V
A
Y
D
A
I
Q
H
-
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
R
V
T
K
------
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
---
W
F
L
E
R
I
F
G
--------
67
PsiBlast_CBE
67.60
32%
-111
- C8 -
3DM5
10
SRP54_PYRFU
A:
[17-313]
----------------------------------------
I
A
R
---
A
-
S
S
V
D
E
A
--
L
---
I
K
E
L
V
R
D
I
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
E
E
K
P
----
P
----
A
G
----
I
--------
S
K
---
K
-
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
T
-------
E
A
---
K
--
P
I
-----
E
I
K
-----
E
--------
K
P
T
I
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
Q
K
-
R
G
Y
K
-
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
---
R
---
Y
H
I
E
-
V
F
-
G
N
P
Q
-
E
-
K
D
A
I
K
L
A
K
E
G
V
D
Y
-
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
L
I
E
E
M
K
Q
I
S
N
V
I
H
------
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
---
R
F
V
S
R
L
L
---------
31
PsiBlast_CBE
67.50
40%
-121
- C8 -
3E70
3
?
C:
[56-324]
------------------------------------------------------------
L
D
E
L
----
E
I
D
L
L
E
A
D
V
A
----
L
E
V
V
D
A
L
R
E
----
K
I
K
----
Q
----
K
L
----
V
GKKVRIG------
G
-
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
T
S
R
RI
D
--
L
I
---
E
--
E
I
-----
R
K
A
-----
E
--------
K
P
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
K
N
-
H
G
F
S
-
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
---
R
---
I
G
V
K
-
V
I
-
K
H
S
Y
-
G
-
A
D
P
A
A
V
A
Y
D
A
I
Q
H
-
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
R
V
T
K
------
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
---
W
F
L
E
R
I
F
G
--------
66
PsiBlast_CBE
67.09
32%
-113
- C8 -
3DM5
9
SRP54_PYRFU
B:
[17-314]
----------------------------------------
I
A
R
---
A
-
S
S
V
D
E
A
--
L
---
I
K
E
L
V
R
D
I
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
E
E
K
P
----
P
----
A
G
----
I
--------
S
K
---
K
-
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
T
-------
E
A
---
K
--
P
I
-----
E
I
K
-----
E
--------
K
P
T
I
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
Q
K
-
R
G
Y
K
-
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
---
R
---
Y
H
I
E
-
V
F
-
G
N
P
Q
-
E
-
K
D
A
I
K
L
A
K
E
G
V
D
Y
-
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
L
I
E
-
M
K
Q
I
S
N
V
I
H
------
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
---
R
F
V
S
R
L
L
---------
33
PsiBlast_CBE
66.86
40%
-123
- C8 -
3DMD
4
?
B:
[56-324]
------------------------------------------------------------
L
D
E
L
----
E
I
D
L
L
E
A
D
V
A
----
L
E
V
V
D
A
L
R
E
----
K
I
K
----
Q
----
K
L
----
V
G
K
K
V
R
IGT
D
K
---
G
-
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
T
S
R
RI
D
--
L
I
---
E
--
E
I
-----
R
K
A
-----
E
--------
K
P
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
K
N
-
H
G
F
S
-
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
---
R
---
I
G
V
K
-
V
I
-
K
H
S
Y
-
G
-
A
D
P
A
A
V
A
Y
D
A
I
Q
H
-
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
R
V
T
K
------
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
---
W
F
L
E
R
I
F
G
--------
71
PsiBlast_CBE
66.57
33%
-116
- C8 -
4C7O
4
SRP54_ECOLI
A:
[28-296]
----------------------------------------------------
K
D
--
T
---
L
R
E
V
----
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
----
K
A
V
G
HEV
N
----
K
S
----
L
--------
T
P
---
G
-
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
-----
E
--
E
N
---
Q
--
T
L
-----
N
L
A
-----
A
-------
Q
P
P
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
-
K
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
---
Q
---
V
G
V
D
-
F
F
-
P
S
D
V
-
G
-
Q
K
P
V
D
I
V
N
A
A
L
K
E
-
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
Q
V
H
A
S
I
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
-----------
90
HHSearch
66.54
32%
-106
- C8 -
4C7O
4
SRP54_ECOLI
A:
[4-296]
--------------------
N
L
T
D
R
L
S
R
T
L
R
N
I
S
G
R
G
--
R
L
T
------
E
D
N
V
K
D
--
T
---
L
R
E
V
----
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
----
K
A
V
----
G
----
H
E
----
V
NKSL----
T
P
---
G
-
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
E
N
--
Q
----------
T
L
-----
N
L
A
-----
A
-------
Q
P
P
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
-
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
---
Q
---
V
G
V
D
-
F
F
-
P
S
D
V
-
G
-
Q
K
P
V
D
I
V
N
A
A
L
K
E
-
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
Q
V
H
A
S
I
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
---
R
I
A
S
R
I
L
G
--------
47
PsiBlast_CBE
63.69
35%
-104
- C8 -
2J7P
7
SRP54_THEAQ
B:
[9-285]
--------------------------------
L
Q
E
A
I
G
R
L
R
G
R
---
G
-
R
I
T
E
E
D
--
L
K
A
T
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
----
E
A
L
----
G
----
K
Q
----
V
--------
L
E
---
S
-
L
T
P
A
E
V
I
---
L
A
T
V
Y
E
A
L
K
--
E
--
A
L
GG
E
A
--
R
L
-----
P
V
L
-----
K
-------
D
R
-
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
-
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
-
E
V
M
D
-
G
-
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
-------------------
53
PsiBlast_CBE
63.12
35%
-105
- C8 -
1NG1
13
SRP54_THEAQ
A:
[9-285]
--------------------------------
L
Q
E
A
I
G
R
L
R
G
R
---
G
-
R
I
T
E
E
D
--
L
K
A
T
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
----
E
A
L
----
G
----
K
Q
----
V
--------
L
E
---
S
-
L
T
P
A
E
V
I
---
L
A
T
V
Y
E
A
L
K
--
E
--
A
L
GG
E
A
--
R
L
-----
P
V
L
-----
K
-------
D
R
-
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
-
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
-
E
V
M
D
-
G
-
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
-------------------
45
PsiBlast_CBE
63.01
35%
-107
- C8 -
3NG1
7
SRP54_THEAQ
B:
[9-285]
--------------------------------
L
Q
E
A
I
G
R
L
R
G
R
---
G
-
R
I
T
E
E
D
--
L
KAT
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
----
E
A
L
----
G
----
K
Q
----
V
--------
L
E
---
S
-
L
T
P
A
E
V
I
---
L
A
T
V
Y
E
A
L
K
--
E
--
A
L
GGE
A
--
R
L
-----
P
V
L
-----
K
-------
D
R
-
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
-
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
-
E
V
M
D
-
G
-
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
-------------------
48
PsiBlast_CBE
62.87
35%
-100
- C8 -
2J7P
10
SRP54_THEAQ
A:
[9-285]
--------------------------------
L
Q
E
A
I
G
R
L
R
G
R
---
G
-
R
I
T
E
E
D
--
L
K
A
T
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
----
E
A
L
----
G
----
K
Q
----
V
--------
L
E
---
S
-
L
T
P
A
E
V
I
---
L
A
T
V
Y
E
A
L
K
--
E
--
A
L
GGE
A
--
R
L
-----
P
V
L
-----
K
-------
D
R
-
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
-
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
-
E
V
M
D
-
G
-
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
-------------------
46
PsiBlast_CBE
62.81
35%
-107
- C8 -
3NG1
6
SRP54_THEAQ
A:
[9-285]
--------------------------------
L
Q
E
A
I
G
R
L
R
G
R
---
G
-
R
I
T
E
E
D
--
L
K
A
T
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
----
E
A
L
----
G
----
K
Q
----
V
--------
L
E
---
S
-
L
T
P
A
E
V
I
---
L
A
T
V
Y
E
A
L
K
--
E
--
A
L
GG
E
A
--
R
L
-----
P
V
L
-----
K
-------
D
R
-
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
-
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
-
E
V
M
D
-
G
-
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
-------------------
52
PsiBlast_CBE
62.79
35%
-102
- C8 -
1OKK
16
SRP54_THEAQ
A:
[9-285]
--------------------------------
L
Q
E
A
I
G
R
L
R
G
R
---
G
-
R
I
T
E
E
D
--
L
K
A
T
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
----
E
A
L
----
G
----
K
Q
----
V
--------
L
E
---
S
-
L
T
P
A
E
V
I
---
L
A
T
V
Y
E
A
L
K
--
E
--
A
L
GG
E
A
--
R
L
-----
P
V
L
-----
K
-------
D
R
-
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
-
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
-
E
V
M
D
-
G
-
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
-------------------
57
PsiBlast_CBE
62.60
35%
-101
- C8 -
1JPJ
1
SRP54_THEAQ
A:
[9-285]
--------------------------------
L
Q
E
A
I
G
R
L
R
G
R
---
G
-
R
I
T
E
E
D
--
L
K
A
T
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
----
E
A
L
----
G
----
K
Q
----
V
--------
L
E
---
S
-
L
T
P
A
E
V
I
---
L
A
T
V
Y
E
A
L
K
--
E
--
A
L
GG
E
A
--
R
L
-----
P
V
L
-----
K
-------
D
R
-
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
-
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
-
E
V
M
D
-
G
-
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
-------------------
99
HHSearch
62.45
36%
-116
* C8 *
1LS1
4
SRP54_THEAQ
A:
[28-294]
----------------------------------------------------
K
A
--
T
---
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
----
E
A
L
----
G
----
K
Q
----
V
--------
L
E
SLT
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
-------------
R
------
L
P
V
-----
L
-------
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
-
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
-
E
V
M
D
-
G
-
E
S
P
E
-
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
------
G
L
E
P
F
Y
P
E
---
R
L
A
G
R
I
L
G
M
-------
56
PsiBlast_CBE
61.84
35%
-106
- C8 -
1JPN
4
SRP54_THEAQ
A:
[9-285]
--------------------------------
L
Q
E
A
I
G
R
L
R
G
R
---
G
-
R
I
T
E
E
D
--
L
K
A
T
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
----
E
A
L
----
G
----
K
Q
----
V
--------
L
E
---
S
-
L
T
P
A
E
V
I
---
L
A
T
V
Y
E
A
L
K
--
E
--
A
L
GG
E
A
--
R
L
-----
P
V
L
-----
K
-------
D
R
-
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
-
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
-
E
V
M
D
-
G
-
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
-------------------
65
PsiBlast_CBE
61.79
35%
-104
- C8 -
1O87
7
SRP54_THEAQ
A:
[9-285]
--------------------------------
L
Q
E
A
I
G
R
L
R
G
R
---
G
-
R
I
T
E
E
D
--
L
K
A
T
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
----
E
A
L
----
G
----
K
Q
----
V
--------
L
E
---
S
-
L
T
P
A
E
V
I
---
L
A
T
V
Y
E
A
L
K
--
E
--
A
L
GG
E
A
--
R
L
-----
P
V
L
-----
K
-------
D
R
-
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
-
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
-
E
V
M
D
-
G
-
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
-------------------
64
PsiBlast_CBE
61.78
35%
-98
- C8 -
1O87
7
SRP54_THEAQ
B:
[9-285]
--------------------------------
L
Q
E
A
I
G
R
L
R
G
R
---
G
-
R
I
T
E
E
D
--
L
KAT
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
----
E
A
L
----
G
----
K
Q
----
V
--------
L
E
---
S
-
L
T
P
A
E
V
I
---
L
A
T
V
Y
E
A
L
K
--
E
--
A
L
GGE
A
--
R
L
-----
P
V
L
-----
K
-------
D
R
-
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
-
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
-
E
V
M
D
-
G
-
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
-------------------
55
PsiBlast_CBE
61.66
35%
-105
- C8 -
1JPN
4
SRP54_THEAQ
B:
[9-285]
--------------------------------
L
Q
E
A
I
G
R
L
R
G
R
---
G
-
R
I
T
E
E
D
--
L
KAT
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
----
E
A
L
----
G
----
K
Q
----
V
--------
L
E
---
S
-
L
T
P
A
E
V
I
---
L
A
T
V
Y
E
A
L
K
--
E
--
A
L
GGE
A
--
R
L
-----
P
V
L
-----
K
-------
D
R
-
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
-
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
-
E
V
M
D
-
G
-
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
-------------------
41
PsiBlast_CBE
61.41
35%
-99
- C8 -
2NG1
4
SRP54_THEAQ
A:
[8-284]
--------------------------------
L
Q
E
A
I
G
R
L
R
G
R
---
G
-
R
I
T
E
E
D
--
L
K
A
T
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
----
E
A
L
----
G
----
K
Q
----
V
--------
L
E
---
S
-
L
T
P
A
E
V
I
---
L
A
T
V
Y
E
A
L
K
--
E
--
A
L
GG
E
A
--
R
L
-----
P
V
L
-----
K
-------
D
R
-
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
-
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
-
E
V
M
D
-
G
-
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
-------------------
42
PsiBlast_CBE
61.35
35%
-110
- C8 -
1LS1
4
SRP54_THEAQ
A:
[9-285]
--------------------------------
L
Q
E
A
I
G
R
L
R
G
R
---
G
-
R
I
T
E
E
D
--
L
K
A
T
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
----
E
A
L
----
G
----
K
Q
----
V
--------
L
E
---
S
-
L
T
P
A
E
V
I
---
L
A
T
V
Y
E
A
L
K
--
E
--
A
L
GG
E
A
--
R
L
-----
P
V
L
-----
K
-------
D
R
-
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
-
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
-
E
V
M
D
-
G
-
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
------
G
L
E
P
F
Y
P
E
-------------------
54
PsiBlast_CBE
59.46
35%
-92
- C8 -
1RJ9
3
SRP54_THEAQ
B:
[14-285]
-------------------------------------
G
R
L
R
G
R
---
G
-
R
I
T
E
E
D
--
L
K
A
T
L
R
E
I
----
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
----
E
A
L
----
G
----
K
Q
----
V
--------
L
E
---
S
-
L
T
P
A
E
V
I
---
L
A
T
V
Y
E
A
L
K
--
E
--
A
L
GG
E
A
--
R
L
-----
P
V
L
-----
K
-------
D
R
-
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
-
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
-
E
V
M
D
-
G
-
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
-------------------