@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu15980: (2016-06-25 )
MAFEGLADRLQQTISKIRGKGKVSEQDVKEMMREVRLALLEADVNFKVVKDFVKKVSERAVGQDVMKSLTPGQQVIKVVQEELTELMGGEESKIAVAKRPPTVIMMVGLQGAGKTTTSGKLANLLRKKHNRKPMLVAADIYRPAAIKQLETLGKQLDMPVFSLGDQVSPVEIAKQAIEKAKEEHYDYVILDTAGRLHIDHELMDELTNVKEIANPEEIFLVVDSMTGQDAVNVAKSFNEQLGLTGVVLTKLDGDTRGGAALSIRAVTNTPIKFAGLGEKLDALEPFHPERMASRILGMGDVLTLIEKAQASVDEDKAKELEQKMRTMSFTLDDFLEQLGQVRNMGPLDELLQMMPGAGKMKGLKNIQVDEKQLNHVEAIIKSMTVLEKEQPDIINASRRKRIAKGSGTSVQEVNRLLKQFDEMKKMMKQMTNMSKGKKKGFKLPFM
Atome Classification :
(34 SA)
.........10........20........30........40........50........60........70........80........90..-------......100.......110.......120.....-..130.......140.......150.......160.......170.......180.......190.......200.......210----..---.------.------...---..220.......230.......240.......250.......260.......270.......280.......290.......300.......310....-...--320.....-.-.330.......340.......350.......360-.........370.......380.......390.......400.......410.......420.......430.......440....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
A
F
E
G
L
A
D
R
L
Q
Q
T
I
S
K
IRGKGKV
S
E
Q
D
V
K
E
M
M
R
E
V
R
L
A
L
L
EADV
N
F
K
V
V
K
D
F
V
K
K
V
S
E
R
A
V
G
Q
D
V
M
K
SLT
P
G
Q
Q
V
I
K
V
V
Q
E
E
L
T
E
L
MGGEE
S
K
-------
I
A
VAKRP
P
T
V
I
M
M
V
GLQGAGKTTT
S
G
K
L
A
N
L
L
R
K
-KHNRK
P
M
L
V
A
ADIYR
P
A
A
I
K
Q
L
E
T
L
G
K
Q
LDM
P
V
F
SLGDQV
S
P
V
E
I
A
K
Q
A
I
E
K
A
K
E
EHY
D
Y
V
I
LDTAG
R
L
H
I
D
H
E
L
M
D
E
L
T
N
V
K
------
E
I---A------
N
------
P
E
E
---
I
F
L
V
V
DSMTG
Q
D
A
V
N
V
A
K
S
F
N
E
QLGL
T
G
V
V
L
T
KLDGDTRG
G
A
A
L
S
I
R
A
VTNT
P
I
K
FAGLGEKLDALEPF
H
P
E
R
M
A
S
R
ILG
M
G
D
V
L
T
L
I
E
K
A
QASV
D
E
D
K
-
A
K
E
--
L
E
Q
K
M
R
T
M-S-F
T
L
D
D
F
L
E
Q
L
G
QVRNMG
P
L
D
E
L
L
Q
MMPGAGKM---KGLKNIQV
D
E
K
Q
L
N
H
V
E
A
I
I
K
S
M
T
V
LEKEQPDII
N
A
S
R
R
K
R
IAKGSGT
S
V
Q
E
V
N
R
L
L
K
Q
F
D
E
M
K
K
M
M
K
Q
M
T
N
MSKGKKKGFKLPFM
21
PsiBlast_CBE
87.79
54%
-106
- C8 -
2XXA
3
SRP54_ECOLI
C:
[7-425]
-------
D
R
L
S
R
T
L
R
N
I
S
G
R
G
R
L
T
E
D
N
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
E
V
N
K
S
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
E
N
Q
T
-------
L
N
L
A
A
Q
P
P
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
-
K
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
F
F
P
S
D
V
G
Q
K
P
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
Q
V
H
------
A
S
---
I
------
N
------
P
V
E
---
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
M
G
D
V
L
S
L
I
E
D
I
E
S
K
V
D
R
A
Q
-
A
E
K
--
L
A
S
K
L
K
K
G
D
G
-
F
D
L
N
D
F
L
E
Q
L
R
Q
M
K
N
M
G
G
M
A
S
L
M
G
-------------------
D
D
K
V
L
V
R
M
E
A
I
I
N
S
M
T
M
K
E
R
A
K
P
E
I
I
K
G
S
R
K
R
R
I
A
A
G
S
G
M
Q
V
Q
D
V
N
R
L
L
K
Q
F
D
D
M
Q
R
---------------------
1
PsiBlast_PDB
87.00
54%
-99
- C8 -
2XXA
3
SRP54_ECOLI
A:
[4-425]
----
N
L
T
D
R
L
S
R
T
L
R
N
I
S
G
R
G
R
L
T
E
D
N
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
E
V
N
K
S
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
E
N
Q
T
-------
L
N
L
A
A
Q
P
P
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
-
K
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
F
F
P
S
D
V
G
Q
K
P
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
Q
V
H
------
A
S
---
I
------
N
------
P
V
E
---
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
M
G
D
V
L
S
L
I
E
D
I
E
S
K
V
D
R
A
Q
-
A
E
K
--
L
A
S
K
L
K
K
G
D
G
-
F
D
L
N
D
F
L
E
Q
L
R
Q
M
K
N
M
G
G
M
A
S
L
M
G
K
------------------
D
D
K
V
L
V
R
M
E
A
I
I
N
S
M
T
M
K
E
R
A
K
P
E
I
I
K
G
S
R
K
R
R
I
A
A
G
S
G
M
Q
V
Q
D
V
N
R
L
L
K
Q
F
D
D
M
Q
R
---------------------
40
PsiBlast_CBE
81.16
39%
-108
- C8 -
3DM5
10
SRP54_PYRFU
A:
[1-430]
M
V
L
D
N
L
G
K
A
L
A
N
T
L
K
K
I
A
R
A
S
S
V
D
E
A
L
I
K
E
L
V
R
D
I
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
E
E
K
P
P
A
G
I
S
K
K
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
T
E
A
K
P
-------
I
E
I
-
K
E
K
P
T
I
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
Q
K
-
R
-
G
Y
K
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
R
Y
H
I
E
V
F
G
N
P
Q
E
K
D
A
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
L
I
E
E
M
K
Q
I
S
------
N
V
---
I
------
H
------
P
H
E
---
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G
L
G
D
I
Q
G
L
L
E
K
F
K
E
L
E
K
E
V
E
-
I
K
E
E
D
I
E
R
F
L
R
G
--
K
-
F
T
L
K
D
M
Y
A
Q
L
E
A
M
R
K
M
G
P
----------------------
I
S
I
G
E
E
R
L
K
K
F
K
V
I
M
D
S
M
T
E
E
E
L
L
N
P
E
I
I
N
Y
S
R
I
K
R
I
A
R
G
S
G
T
S
T
K
D
V
K
E
L
L
D
Q
Y
R
Q
M
K
K
L
F
K
S
M
N
---------------
39
PsiBlast_CBE
81.05
39%
-111
- C8 -
3DM5
9
SRP54_PYRFU
B:
[1-430]
M
V
L
D
N
L
G
K
A
L
A
N
T
L
K
K
I
A
R
A
S
S
V
D
E
A
L
I
K
E
L
V
R
D
I
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
E
E
K
P
P
A
G
I
S
K
K
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
T
E
A
K
P
-------
I
E
I
-
K
E
K
P
T
I
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
Q
K
-
R
-
G
Y
K
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
R
Y
H
I
E
V
F
G
N
P
Q
E
K
D
A
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
L
I
E
-
M
K
Q
I
S
------
N
V
---
I
------
H
------
P
H
E
---
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G
L
G
D
I
Q
G
L
L
E
K
F
K
E
L
E
K
E
V
E
-
I
K
E
E
D
I
E
R
F
L
R
G
--
K
-
F
T
L
K
D
M
Y
A
Q
L
E
A
M
R
K
M
G
P
-----------------------
S
I
G
E
E
R
L
K
K
F
K
V
I
M
D
S
M
T
E
E
E
L
L
N
P
E
I
I
N
Y
S
R
I
K
R
I
A
R
G
S
G
T
S
T
K
D
V
K
E
L
L
D
Q
Y
R
Q
M
K
K
L
F
K
S
M
N
---------------
81
HHSearch
80.77
38%
-105
- C8 -
3DM5
10
SRP54_PYRFU
A:
[1-435]
M
V
L
D
N
L
G
K
A
L
A
N
T
L
K
K
I
A
R
A
S
S
V
D
E
A
L
I
K
E
L
V
R
D
I
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
E
E
K
P
P
A
G
I
S
K
K
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
T
E
A
K
P
-------
I
E
I
-
K
E
K
P
T
I
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
Q
K
-
R
-
G
Y
K
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
R
Y
H
I
E
V
F
G
N
P
Q
E
K
D
A
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
L
I
E
E
M
K
Q
I
S
------
N
V
---
I
------
H
------
P
H
E
---
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G
L
G
D
I
Q
G
L
L
E
K
F
K
E
L
E
K
E
V
E
I
K
E
E
--
D
I
E
R
F
L
R
G
-
K
-
F
T
L
K
D
M
Y
A
Q
L
E
A
M
R
K
M
G
P
----------------------
I
S
I
G
E
E
R
L
K
K
F
K
V
I
M
D
S
M
T
E
E
E
L
L
N
P
E
I
I
N
Y
S
R
I
K
R
I
A
R
G
S
G
T
S
T
K
D
V
K
E
L
L
D
Q
Y
R
Q
M
K
K
L
F
K
S
M
N
K
R
Q
L
S
----------
23
PsiBlast_CBE
80.41
50%
-92
- C7 -
2FFH
7
SRP54_THEAQ
B:
[2-418]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
R
L
-------
P
V
L
K
D
R
--
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
-
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
------
E
V
---
L
------
G
------
P
D
E
---
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
V
A
S
L
A
E
K
V
R
A
A
--------------
E
L
-------
S
L
E
D
F
L
K
Q
M
Q
N
L
K
R
L
G
P
F
S
E
I
L
G
L
L
P
G
V
--
P
---
Q
G
L
K
---
V
D
E
K
A
I
K
R
L
E
A
I
V
L
S
M
T
P
E
E
R
K
D
P
R
I
L
N
G
S
R
R
K
R
I
A
K
G
S
G
T
S
V
Q
E
V
N
R
F
I
K
A
F
E
E
M
K
A
L
M
K
S
L
E
-----
K
---------
24
PsiBlast_CBE
80.31
56%
-109
- C8 -
4C7O
5
SRP54_ECOLI
C:
[2-298]
--
F
D
N
L
T
D
R
L
S
R
T
L
R
N
I
S
G
R
G
R
L
T
E
D
N
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
E
V
N
K
S
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
E
N
Q
T
-------
L
N
L
A
A
Q
P
P
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
-
K
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
F
F
P
S
D
V
G
Q
K
P
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
Q
V
H
------
A
S
---
I
------
N
------
P
V
E
---
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
M
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
79.83
52%
-123
- C8 -
2J46
5
SRP54_THEAQ
B:
[2-297]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
-
A
R
-------
L
P
V
L
K
-
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
-
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
------
E
V
---
L
------
G
------
P
D
E
---
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
V
---------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
79.60
52%
-123
- C8 -
2J45
6
SRP54_THEAQ
A:
[2-297]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
-
A
R
-------
L
P
V
L
K
-
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
-
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
------
E
V
---
L
------
G
------
P
D
E
---
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
V
---------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
79.56
52%
-123
- C8 -
2J46
5
SRP54_THEAQ
A:
[2-296]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
-
A
R
-------
L
P
V
L
K
-
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
-
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
------
E
V
---
L
------
G
------
P
D
E
---
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
----------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
79.37
46%
-
- C8 -
2IY3
-
SRP54_SULSO (first)
A:
[2-429]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
-
A
R
-------
L
P
V
L
K
-
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
-
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
------
E
V
---
L
------
G
------
P
D
E
---
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
I
E
S
I
L
E
K
V
K
G
L
E
E
Y
D
K
I
Q
K
K
--
M
E
D
V
M
E
G
K
-
G
K
L
T
L
R
D
V
Y
A
Q
I
I
A
L
R
K
M
G
P
L
S
K
V
L
Q
H
I
P
G
L
G
I
M
LPT
P
S
E
D
Q
L
K
I
G
E
E
K
I
R
R
W
L
A
A
L
N
S
M
T
Y
K
E
L
E
N
P
N
I
I
D
K
S
R
M
R
R
I
A
E
G
S
G
L
E
V
E
E
V
R
E
L
L
E
W
Y
N
N
M
N
R
L
L
K
------------------
80
HHSearch
79.29
49%
-91
- C7 -
2FFH
7
SRP54_THEAQ
A:
[1-418]
-
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
R
---------
L
P
V
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
-
K
-
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
------
E
V
---
L
------
G
------
P
D
E
---
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
V
A
S
L
A
E
K
V
R
A
A
--------------------
E
-
L
S
L
E
D
F
L
K
Q
M
Q
N
L
K
R
L
G
P
F
S
E
I
L
G
L
L
P
G
V
P
Q
G
---
L
-----
K
V
D
E
K
A
I
K
R
L
E
A
I
V
L
S
M
T
P
E
E
R
K
D
P
R
I
L
N
G
S
R
R
K
R
I
A
K
G
S
G
T
S
V
Q
E
V
N
R
F
I
K
A
F
E
E
M
K
A
L
M
K
S
L
E
K
--------------
10
PsiBlast_PDB
78.94
52%
-117
- C8 -
2C04
2
SRP54_THEAQ
A:
[2-297]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
-
A
R
-------
L
P
V
L
K
-
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
-
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
------
E
V
---
L
------
G
------
P
D
E
---
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
V
---------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
78.85
50%
-90
- C7 -
2FFH
7
SRP54_THEAQ
A:
[2-418]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
R
L
-------
P
V
L
K
D
R
--
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
-
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
------
E
V
---
L
------
G
------
P
D
E
---
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
V
A
S
L
A
E
K
V
R
A
A
--------------
E
L
-------
S
L
E
D
F
L
K
Q
M
Q
N
L
K
R
L
G
P
F
S
E
I
L
G
L
L
P
G
V
--
P
---
Q
G
L
K
---
V
D
E
K
A
I
K
R
L
E
A
I
V
L
S
M
T
P
E
E
R
K
D
P
R
I
L
N
G
S
R
R
K
R
I
A
K
G
S
G
T
S
V
Q
E
V
N
R
F
I
K
A
F
E
E
M
K
A
L
M
K
S
L
E
-----
K
---------
8
PsiBlast_PDB
78.79
52%
-118
- C8 -
2C03
10
SRP54_THEAQ
A:
[2-295]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
-
A
R
-------
L
P
V
L
K
-
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
-
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
------
E
V
---
L
------
G
------
P
D
E
---
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
78.35
52%
-119
- C8 -
2C03
10
SRP54_THEAQ
B:
[2-297]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
-
A
R
-------
L
P
V
L
K
-
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
-
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
------
E
V
---
L
------
G
------
P
D
E
---
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
V
---------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
78.33
52%
-116
- C8 -
1JPN
4
SRP54_THEAQ
A:
[2-296]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
-
A
R
-------
L
P
V
L
K
-
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
-
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
------
E
V
---
L
------
G
------
P
D
E
---
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
----------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
78.31
50%
-89
- C7 -
2FFH
9
SRP54_THEAQ
C:
[2-418]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
R
L
-------
P
V
L
K
D
R
--
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
-
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
------
E
V
---
L
------
G
------
P
D
E
---
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
V
A
S
L
A
E
K
V
R
A
A
--------------
E
L
-------
S
L
E
D
F
L
K
Q
M
Q
N
L
K
R
L
G
P
F
S
E
I
L
G
L
L
P
G
V
--
P
---
Q
G
L
K
---
V
D
E
K
A
I
K
R
L
E
A
I
V
L
S
M
T
P
E
E
R
K
D
P
R
I
L
N
G
S
R
R
K
R
I
A
K
G
S
G
T
S
V
Q
E
V
N
R
F
I
K
A
F
E
E
M
K
A
L
M
K
S
L
E
-----
K
---------
27
PsiBlast_CBE
78.26
52%
-121
- C8 -
2J45
4
SRP54_THEAQ
B:
[2-297]
--
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
-
A
R
-------
L
P
V
L
K
-
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
-
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
------
E
V
---
L
------
G
------
P
D
E
---
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
V
---------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
78.04
56%
-108
- C8 -
4C7O
4
SRP54_ECOLI
A:
[4-296]
----
N
L
T
D
R
L
S
R
T
L
R
N
I
S
G
R
G
R
L
T
E
D
N
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
E
V
N
K
S
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
E
N
Q
T
-------
L
N
L
A
A
Q
P
P
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
-
K
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
F
F
P
S
D
V
G
Q
K
P
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
Q
V
H
------
A
S
---
I
------
N
------
P
V
E
---
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------
85
HHSearch
77.37
56%
-107
- C8 -
4C7O
4
SRP54_ECOLI
A:
[4-296]
----
N
L
T
D
R
L
S
R
T
L
R
N
I
S
G
R
G
R
L
T
E
D
N
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
E
V
N
K
S
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
E
N
Q
T
-------
L
N
L
A
A
Q
P
P
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
-
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
F
F
P
S
D
V
G
Q
K
P
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
Q
V
H
------
A
S
---
I
------
N
------
P
V
E
---
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------
92
HHSearch
76.40
51%
-120
- C8 -
1LS1
4
SRP54_THEAQ
A:
[1-295]
-
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
R
---------
L
P
V
L
K
D
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
-
K
-
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
------
E
V
---
L
------
G
------
P
D
E
---
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
------
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------
98
HHSearch
69.85
34%
-124
- C8 -
2YHS
5
FTSY_ECOLI
A:
[225-495]
----------------------------
D
D
L
F
E
E
L
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
----
Q
L
R
D
A
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
E
P
-------
L
N
V
E
G
K
A
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
Q
-
Q
-
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
V
I
A
Q
H
T
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
------
R
V
---
M
K
K
L
DVE
A
------
P
H
E
---
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
R
------------------------------------------------------------------------------------------------------------------------------------------------------------
43
PsiBlast_CBE
68.42
37%
-120
- C8 -
3DMD
4
?
B:
[37-324]
----
G
L
L
D
R
I
L
T
V
--------
E
I
K
E
K
D
V
D
K
A
L
D
E
L
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
G
K
K
V
R
I
G
T
D
K
G
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
--
E
T
S
R
RID
L
I
E
E
I
R
K
A
E
K
P
-
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
-
K
-
N
H
G
F
S
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
R
I
G
V
K
V
I
K
H
S
Y
G
A
D
P
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
------
R
V
---
T
------
K
------
P
N
L
---
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------
64
PsiBlast_CBE
60.80
41%
-119
- C8 -
1VMA
1
?
B:
[94-304]
------------------------------------------------------------------------------------------
D
T
K
-------
L
N
V
P
P
E
P
P
F
V
I
M
V
V
G
V
N
G
T
G
K
T
T
S
C
G
K
L
A
K
M
F
V
D
-
E
-
G
K
S
V
V
L
A
A
A
D
T
F
R
A
A
A
I
E
Q
L
K
I
W
G
E
R
V
G
A
T
V
I
S
H
S
E
G
A
D
P
A
A
V
A
F
D
A
V
A
H
A
L
A
R
N
K
D
V
V
I
I
D
T
A
G
R
L
H
T
K
K
N
L
M
E
E
L
R
K
V
H
------
R
V
---
V
------
K
KKIPDA
P
H
E
---
T
L
L
V
I
D
A
T
T
G
Q
N
G
L
V
Q
A
K
I
F
K
E
A
V
N
V
T
G
I
I
L
T
K
L
D
G
T
A
K
G
G
I
T
L
A
I
A
R
E
L
G
I
P
I
K
F
I
G
V
G
E
K
A
E
D
L
R
P
F
D
P
E
A
F
V
E
V
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------
48
PsiBlast_CBE
58.47
35%
-99
- C8 -
4C7O
5
FTSY_ECOLI
D:
[19-267]
-----------------------------------------
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
----
R
K
Q
L
R
D
A
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
E
P
-------
L
N
V
E
G
K
A
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
-
E
-
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
V
I
A
Q
H
T
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
---
E
------
A
------
P
H
E
---
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
60
PsiBlast_CBE
57.41
42%
-125
- C8 -
2IYL
3
FTSY_THEAQ
D:
[95-282]
------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
N
--
L
G
K
K
V
M
F
C
A
G
D
T
------
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
Q
G
P
E
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
------
R
A
IAK
A
------
D
------
P
E
E
PKE
V
W
L
V
L
D
A
V
T
G
Q
--
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------
49
PsiBlast_CBE
57.28
35%
-96
- C8 -
4C7O
4
FTSY_ECOLI
B:
[19-267]
-----------------------------------------
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
----
R
K
Q
L
R
D
A
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
E
P
-------
L
N
V
E
G
K
A
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
-
E
-
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
V
I
A
Q
H
T
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
---
E
------
A
------
P
H
E
---
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
53
PsiBlast_CBE
56.56
42%
-113
- C8 -
2Q9C
7
FTSY_THEAQ
A:
[115-302]
------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
-
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
Q
G
P
E
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
------
R
A
I
A
K
A
------
D
------
P
E
E
PK
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------
58
PsiBlast_CBE
56.51
42%
-104
- C8 -
2J7P
9
FTSY_THEAQ
E:
[94-281]
------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
N
--
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
Q
G
P
E
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
------
R
A
IAK
A
------
D
------
P
E
E
PKE
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------
51
PsiBlast_CBE
56.08
42%
-106
- C8 -
1OKK
8
FTSY_THEAQ
D:
[114-301]
------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
-
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
Q
G
P
E
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
------
R
A
IAK
A
------
D
------
P
E
E
PKE
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------
55
PsiBlast_CBE
55.93
42%
-116
- C8 -
2Q9B
11
FTSY_THEAQ
A:
[115-302]
------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
-
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
Q
G
P
E
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
------
R
A
I
A
K
A
------
D
------
P
E
E
PK
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------
59
PsiBlast_CBE
55.06
42%
-106
- C8 -
2J7P
5
FTSY_THEAQ
D:
[94-281]
------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
N
--
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
Q
G
P
E
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
------
R
A
I
A
K
A
------
D
------
P
E
E
PK
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------
66
PsiBlast_CBE
53.78
41%
-105
- C8 -
1RJ9
3
FTSY_THEAQ
A:
[115-302]
------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
-
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
Q
G
P
E
G
T
D
S
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
------
R
A
I
A
K
A
------
D
------
P
E
E
PK
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------