@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu16390: (2016-06-25 )
MSTRDLSVLISVVLIVAMLVIPFPPWLLSILIIINISLALIVLLTTMNMQEALQFSIFPSLLLLLTLFRLGLNVSTTRSILSHGEGGKVVETFGNFVVGGNVLVGLVVFIILIIIQFIVITKGAERVSEVAARFTLDAMPGKQMSIDADLNAGMITEQEAKHRREKVAREADFYGAMDGASKFVKGDAIAGIIIVMINIIFGIVIGMLQQGMSIQEAASHFTMLTVGDGIVSQIPALLISTATGIVVTRAASEGNLGHDITGQLFAYPKLLYVAAATIMLLGIFTPIGILLTGPLAGLLAFGAYTLSKSGKEKEEVDEILEEEAEVDELKSPESVVQLLHIDPIEFEFGYGLIPLADANQGGDLLDRIVMIRRQLALELGLVIPVVRIRDNIALQPNEYRLKIKGNEVAKGELLLDHYLAMSPTPEDDLIEGIETVEPSFGLPAKWISEAVKDEADMLGYTVVDPASVVSTHITEKIKQHAHELIGRQETKQLIDHLKESYPVLVEEVTPNPLSVGDIQKVLAKLLKEKVSIRNLVTIFETLADYGKLTTDSDLLTEYTRQALAKQITAQFAKENEVLKVVTCSGRVEKAIADGVQQTEHGNYLSLEPDISESIVRSVAKEAEQLSLRQETAILLCSPPVRMYVKQLLERYFPDLPVLSYNELEANVEVQSIGVVDI
Atome Classification :
(20 SA)
----------------------.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310-.......320.......330.......340.......350.......360...--....370.......380.----......390--------........400.......410.......420.......430..-.-.....440.......450.......460.......470.......480.......490.......500.....--------..510.......520.......530.......540.......-550......---.560.......570.......580.......590.......600.......610--.......620.......630--.-......640-----.........650.......660.......670.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------MST
R
D
L
S
V
L
I
S
V
V
L
I
V
A
M
L
VIPF
P
P
W
L
L
S
I
L
I
I
I
N
I
S
L
A
L
I
V
L
L
TTM
N
M
Q
E
A
L
Q
F
S
I
F
P
S
L
L
L
L
L
T
L
F
R
LGLN
V
S
T
T
R
S
I
L
SHGEGG
K
V
V
E
T
FG
N
F
V
VG
G
N
V
L
V
G
L
V
V
F
I
I
L
I
I
I
Q
F
I
V
ITK
G
A
E
R
V
S
E
V
A
A
R
F
TLDAMPGK
Q
M
S
IDADLNAGMI
T
E
Q
E
A
K
H
R
R
E
K
V
A
R
E
A
D
FYGAMD
G
A
S
K
FVKGD
A
I
A
G
I
I
I
V
M
I
N
I
I
F
G
I
V
I
G
M
L
Q
QGM
S
I
Q
E
A
ASH
F
T
M
L
T
VGD
G
I
V
S
Q
I
P
A
L
L
I
STAT
G
I
V
V
T
R
AASEGNLGHDI
T
G
Q
L
F
A
Y
P
K
L
L
Y
V
A
A
A
T
I
M
L
L
G
I
FT
P
I
G
I
L
LT
G
P
L
A
G
L
L
A
F
G
A
Y
TLSKSGK
E
-
K
E
E
V
D
E
I
L
E
E
E
A
E
V
D
ELK
S
P
E
S
V
V
Q
L
L
HIDP
I
E
F
EFGYGLIPLADANQ
G
G
D
L
L
--
D
R
I
V
M
I
R
R
Q
L
A
L
E
LG
L
V
I
----
P
V
V
R
IRD
N
---------
I
A
LQPN
E
Y
R
L
K
I
KGNEVAK
G
E
L
L
L
D
H
Y
LAMSPT
P
E
D
D
L
I
E
-
G
I
-
E
-TVEPSFGL
P
A
K
W
I
S
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A
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KD
E
A
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ML
G
Y
TVV
D
P
A
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V
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T
H
I
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I
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Q
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A
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L
I
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R
Q
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T
K
Q
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D
H
L
K
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SY
P
V
L
V
EE--------VTPNPL
S
V
G
D
I
Q
K
V
L
A
K
L
L
K
E
K
V
S
I
R
N
L
V
T
I
F
E
T
L
A
D
YGKLT-T
D
S
D
L
L
T
E
Y
---
T
R
Q
A
L
A
K
Q
I
T
A
Q
F
AKEN
E
V
L
K
V
V
TCSG
R
V
E
K
A
I
A
DGVQQTEHG
N
Y
L
SLEPD
I
S
E
--
S
I
V
R
S
V
A
K
E
A
E
Q
L
S
LRQ
E
T
A
--
I
-
L
L
CSP
P
V
-------
R
M
Y
V
K
Q
L
L
E
R
YFPDLP
V
L
S
YNELEA
N
V
E
V
Q
S
I
GVVDI
20
Fugue
88.25
100%
-152
- C3 -
3MIX
-
FLHA_BACSU
A:
[318-676]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
I
L
E
E
E
A
E
V
D
E
L
K
S
P
E
S
V
V
Q
L
L
H
I
D
P
I
E
F
E
F
G
Y
G
L
I
P
L
A
D
A
N
Q
G
G
D
L
L
--
D
R
I
V
M
I
R
R
Q
L
A
L
E
L
G
L
V
I
----
P
V
V
R
I
R
D
N
---------
I
A
L
Q
P
N
E
Y
R
L
K
I
K
G
N
E
V
A
K
G
E
L
L
L
D
H
Y
L
A
-------------------------------------------
T
V
V
D
P
A
S
V
V
S
T
H
I
T
E
K
I
K
Q
H
A
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R
Q
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T
K
Q
L
I
D
H
L
K
E
S
Y
P
V
L
V
E
E
--------
V
T
P
N
P
L
S
V
G
D
I
Q
K
V
L
A
K
L
L
K
E
K
V
S
I
R
N
L
V
T
I
F
E
T
L
A
D
Y
G
K
L
T
-
T
D
S
D
L
L
T
E
Y
---
T
R
Q
A
L
A
K
Q
I
T
A
Q
F
A
K
E
N
E
V
L
K
V
V
T
C
S
G
R
V
E
K
A
I
A
D
G
V
Q
------
Y
L
S
L
E
P
D
I
S
E
--
S
I
V
R
S
V
A
K
E
A
E
Q
L
S
L
R
Q
E
T
A
--
I
-
L
L
C
S
P
P
V
-------
R
M
Y
V
K
Q
L
L
E
R
Y
F
P
D
L
P
V
L
S
Y
N
E
L
E
A
N
V
E
V
Q
S
I
G
V
V
D
-
12
HHSearch
72.25
36%
-120
- C3 -
3MYD
-
FLHA_HELPY
A:
[391-731]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
V
L
K
I
E
F
L
E
L
A
L
G
Y
Q
L
I
S
L
A
D
M
K
Q
G
G
D
L
L
--
E
R
I
R
G
I
R
K
K
I
A
S
D
Y
G
F
L
M
----
P
Q
I
R
I
R
D
N
---------
L
Q
L
P
P
T
H
Y
E
I
K
L
K
G
I
V
I
G
E
G
M
V
M
P
D
K
F
L
A
M
N
T
G
F
V
N
R
E
I
E
-
G
I
-
P
-
T
K
E
P
A
F
G
M
D
A
L
W
I
D
A
K
N
K
E
E
A
I
I
Q
G
Y
T
I
I
D
P
S
T
V
I
A
T
H
T
S
E
L
V
K
K
Y
A
E
D
F
I
T
K
D
E
V
K
S
L
L
E
R
L
A
K
D
Y
P
T
I
V
E
E
--------
S
--
K
K
I
P
T
G
A
I
R
S
V
L
Q
A
L
L
H
E
K
I
P
I
K
D
M
L
T
I
L
E
T
I
T
D
I
A
P
L
V
Q
N
D
V
N
I
L
T
E
Q
---
V
R
A
R
L
S
R
V
I
T
N
A
F
K
S
E
D
G
R
L
K
F
L
T
F
S
T
D
S
E
Q
F
L
L
N
K
L
R
E
N
G
T
S
K
S
L
L
L
N
V
G
E
L
Q
--
K
L
I
E
G
V
S
E
E
A
M
K
V
L
Q
K
G
I
A
P
--
V
I
L
I
V
E
P
N
L
-------
R
K
A
L
S
N
Q
M
E
Q
A
R
I
D
V
V
V
L
S
H
A
E
L
D
P
N
S
N
F
E
A
L
G
T
I
H
I
1
PsiBlast_PDB
71.94
36%
-120
- C3 -
3MYD
-
FLHA_HELPY
A:
[385-731]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
Q
A
I
D
E
V
---------
L
K
I
E
F
L
E
L
A
L
G
Y
Q
L
I
S
L
A
D
M
K
Q
G
G
D
L
L
--
E
R
I
R
G
I
R
K
K
I
A
S
D
Y
G
F
L
M
----
P
Q
I
R
I
R
D
N
---------
L
Q
L
P
P
T
H
Y
E
I
K
L
K
G
I
V
I
G
E
G
M
V
M
P
D
K
F
L
A
M
N
T
G
F
V
N
R
E
I
E
-
G
I
-
P
-
T
K
E
P
A
F
G
M
D
A
L
W
I
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A
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N
K
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A
I
I
Q
G
Y
T
I
I
D
P
S
T
V
I
A
T
H
T
S
E
L
V
K
K
Y
A
E
D
F
I
T
K
D
E
V
K
S
L
L
E
R
L
A
K
D
Y
P
T
I
V
E
E
--------
S
K
K
I
P
--
T
G
A
I
R
S
V
L
Q
A
L
L
H
E
K
I
P
I
K
D
M
L
T
I
L
E
T
I
T
D
I
A
P
L
V
Q
N
D
V
N
I
L
T
E
Q
---
V
R
A
R
L
S
R
V
I
T
N
A
F
K
S
E
D
G
R
L
K
F
L
T
F
S
T
D
S
E
Q
F
L
L
N
K
L
R
--
E
N
G
T
S
K
S
L
L
L
N
V
G
E
L
Q
K
L
I
E
G
V
S
E
E
A
M
K
V
-
L
Q
K
G
I
A
P
V
I
-
L
I
V
E
P
N
L
-------
R
K
A
L
S
N
Q
M
E
Q
A
R
I
D
V
V
V
L
S
H
A
E
L
D
P
N
S
N
F
E
A
L
G
T
I
H
I
10
HHSearch
70.79
36%
-135
- C3 -
3A5I
-
FLHA_SALTY
A:
[355-691]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
D
V
Q
L
E
D
S
L
G
M
E
V
G
Y
R
L
I
P
M
V
D
F
Q
Q
D
G
E
L
L
--
G
R
I
R
S
I
R
K
K
F
A
Q
D
M
G
F
L
P
----
P
V
V
H
I
R
D
N
---------
M
D
L
Q
P
A
R
Y
R
I
L
M
K
G
V
E
I
G
S
G
D
A
Y
P
G
R
W
L
A
I
N
P
G
T
A
A
G
T
L
P
-
G
E
-
K
-
T
V
D
P
A
F
G
L
D
A
I
W
I
E
S
A
L
K
E
Q
A
Q
I
Q
G
F
T
V
V
E
A
S
T
V
V
A
T
H
L
N
H
L
I
G
Q
F
S
A
E
L
F
G
R
Q
E
A
Q
Q
L
L
D
R
V
S
Q
E
M
P
K
L
T
E
D
--------
L
V
P
G
V
V
T
L
T
T
L
H
K
V
L
Q
N
L
L
A
E
K
V
P
I
R
D
M
R
T
I
L
E
T
L
A
E
H
A
P
L
Q
-
S
D
P
H
E
L
T
A
V
---
V
R
V
A
L
G
R
A
I
T
Q
Q
W
F
P
G
N
E
E
V
Q
V
I
G
L
D
T
A
L
E
R
L
L
L
Q
A
L
Q
G
G
-----
G
G
L
E
P
G
L
A
D
--
R
L
L
A
Q
T
Q
E
A
L
S
R
Q
E
M
L
G
A
P
P
--
V
-
L
L
V
N
H
A
L
-------
R
P
L
L
S
R
F
L
R
R
S
L
P
Q
L
V
V
L
S
N
L
E
L
S
D
N
R
H
I
R
M
T
A
T
I
G
G
2
PsiBlast_PDB
68.22
38%
-122
- C3 -
3A5I
-
FLHA_SALTY
A:
[361-684]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
S
L
G
M
E
V
G
Y
R
L
I
P
M
V
D
F
Q
Q
D
G
E
L
L
--
G
R
I
R
S
I
R
K
K
F
A
Q
D
M
G
F
L
P
----
P
V
V
H
I
R
D
N
---------
M
D
L
Q
P
A
R
Y
R
I
L
M
K
G
V
E
I
G
S
G
D
A
Y
P
G
R
W
L
A
I
N
P
G
T
A
A
G
T
L
P
-
G
E
-
K
-
T
V
D
P
A
F
G
L
D
A
I
W
I
E
S
A
L
K
E
Q
A
Q
I
Q
G
F
T
V
V
E
A
S
T
V
V
A
T
H
L
N
H
L
I
G
Q
F
S
A
E
L
F
G
R
Q
E
A
Q
Q
L
L
D
R
V
S
Q
E
M
P
K
L
T
E
D
--------
L
V
P
G
V
V
T
L
T
T
L
H
K
V
L
Q
N
L
L
A
E
K
V
P
I
R
D
M
R
T
I
L
E
T
L
A
E
H
A
P
L
Q
-
S
D
P
H
E
L
T
A
V
---
V
R
V
A
L
G
R
A
I
T
Q
Q
W
F
P
G
N
E
E
V
Q
V
I
G
L
D
T
A
L
E
R
L
L
L
Q
A
L
Q
-----
G
G
G
G
L
E
P
G
L
A
D
-----
R
L
L
A
Q
T
Q
E
A
L
S
-
R
Q
E
------
M
L
G
A
P
P
V
L
L
V
N
HAL
R
P
L
L
S
R
F
L
R
R
S
L
P
Q
L
V
V
L
S
N
L
E
L
S
D
N
R
H
I
R
-------
19
Fugue
67.80
28%
-127
* C3 *
2X49
6
A:
[1-333]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
H
M
T
E
T
V
P
L
I
L
L
V
P
K
S
R
R
E
D
L
E
K
A
Q
L
A
E
R
L
R
S
Q
F
F
I
D
Y
G
V
R
L
----
P
E
V
L
L
R
D
G
---------
E
G
L
D
D
N
S
I
V
L
L
I
N
E
I
R
V
E
Q
F
T
V
Y
F
D
L
M
R
V
V
N
Y
S
D
E
V
V
S
F
G
-
I
N
-
P
-
T
I
H
Q
Q
G
S
S
Q
Y
F
W
V
T
H
E
E
G
E
K
L
R
E
L
G
Y
V
L
R
N
A
L
D
E
L
Y
H
C
L
A
V
T
L
A
R
N
V
N
E
Y
F
G
I
Q
E
T
K
H
M
L
D
Q
L
E
A
K
F
P
D
L
L
K
E
--------
V
L
R
H
-
A
T
V
Q
R
I
S
E
V
L
Q
R
L
L
S
E
R
V
S
V
R
N
M
K
L
I
M
E
A
L
A
L
W
A
P
R
E
-
K
D
V
I
N
L
V
E
H
---
I
R
G
A
M
A
R
Y
I
C
H
K
F
A
N
G
G
E
-
L
R
A
V
M
V
S
A
E
V
E
D
V
I
R
K
G
I
R
Q
T
S
G
S
T
F
L
S
L
D
P
E
A
S
A
--
N
L
M
D
L
I
T
L
K
L
D
D
L
L
I
A
H
K
D
L
--
V
-
L
L
T
S
V
D
V
-------
R
R
F
I
K
K
M
I
E
G
R
F
P
D
L
E
V
L
S
F
G
E
I
A
D
S
K
S
V
N
V
I
K
T
I
--
13
HHSearch
67.77
27%
-139
- C3 -
2X49
6
A:
[4-333]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
E
T
V
P
L
I
L
L
V
P
K
S
R
R
E
D
L
E
------
K
A
--
Q
L
A
E
R
L
R
S
Q
F
F
I
D
Y
G
V
R
L
----
P
E
V
L
L
R
D
G
---------
E
G
L
D
D
N
S
I
V
L
L
I
N
E
I
R
V
E
Q
F
T
V
Y
F
D
L
M
R
V
V
N
Y
S
D
E
V
V
-
S
F
-
G
I
N
P
-
T
I
H
Q
Q
G
S
S
Q
Y
F
W
V
T
H
E
E
G
E
K
L
R
E
L
G
Y
V
L
R
N
A
L
D
E
L
Y
H
C
L
A
V
T
L
A
R
N
V
N
E
Y
F
G
I
Q
E
T
K
H
M
L
D
Q
L
E
A
K
F
P
D
L
L
K
E
--------
V
L
-
R
H
A
T
V
Q
R
I
S
E
V
L
Q
R
L
L
S
E
R
V
S
V
R
N
M
K
L
I
M
E
A
L
A
L
W
A
P
R
E
-
K
D
V
I
N
L
V
E
H
---
I
R
G
A
M
A
R
Y
I
C
H
K
F
A
N
-
G
G
E
L
R
A
V
M
V
S
A
E
V
E
D
V
I
R
K
G
I
R
Q
T
S
G
S
T
F
L
S
L
D
P
E
A
S
A
--
N
L
M
D
L
I
T
L
K
L
D
D
L
L
I
A
H
K
D
L
--
V
-
L
L
T
S
V
D
V
-------
R
R
F
I
K
K
M
I
E
G
R
F
P
D
L
E
V
L
S
F
G
E
I
A
D
S
K
S
V
N
V
I
K
T
I
--
4
PsiBlast_PDB
63.84
29%
-133
- C3 -
2X4A
3
A:
[31-333]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
S
Q
F
F
I
D
Y
G
V
R
L
----
P
E
V
L
L
R
D
G
---------
E
G
L
D
D
N
S
I
V
L
L
I
--
N
E
I
R
V
E
Q
F
T
V
Y
F
D
L
M
R
V
V
N
Y
S
D
E
V
V
S
F
G
I
-
N
P
T
I
H
Q
Q
G
S
S
Q
Y
F
W
V
T
H
E
E
G
E
K
L
R
E
L
G
Y
V
L
R
N
A
L
D
E
L
Y
H
C
L
A
V
T
L
A
R
N
V
N
E
Y
F
G
I
Q
E
T
K
H
M
L
D
Q
L
E
A
K
F
P
D
L
L
K
E
--------
V
L
R
H
A
-
T
V
Q
R
I
S
E
V
L
Q
R
L
L
S
E
R
V
S
V
R
N
M
K
L
I
M
E
A
L
A
L
W
A
P
R
E
-
K
D
V
I
N
L
V
E
H
---
I
R
G
A
M
A
R
Y
I
C
H
K
F
A
N
G
G
E
-
L
R
A
V
M
V
S
A
E
V
E
D
V
I
R
K
G
I
R
Q
T
S
G
S
T
F
L
S
L
D
P
E
A
S
A
--
N
L
M
D
L
I
T
L
K
L
D
D
L
L
I
A
H
K
D
L
--
V
-
L
L
T
S
V
D
V
-------
R
R
F
I
K
K
M
I
E
G
R
F
P
D
L
E
V
L
S
F
G
E
I
A
D
S
K
S
V
N
V
I
K
T
I
--
3
PsiBlast_PDB
63.51
29%
-132
- C3 -
2X49
6
A:
[31-333]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
S
Q
F
F
I
D
Y
G
V
R
L
----
P
E
V
L
L
R
D
G
---------
E
G
L
D
D
N
S
I
V
L
L
I
--
N
E
I
R
V
E
Q
F
T
V
Y
F
D
L
M
R
V
V
N
Y
S
D
E
V
V
S
F
G
I
-
N
P
T
I
H
Q
Q
G
S
S
Q
Y
F
W
V
T
H
E
E
G
E
K
L
R
E
L
G
Y
V
L
R
N
A
L
D
E
L
Y
H
C
L
A
V
T
L
A
R
N
V
N
E
Y
F
G
I
Q
E
T
K
H
M
L
D
Q
L
E
A
K
F
P
D
L
L
K
E
--------
V
L
R
H
A
-
T
V
Q
R
I
S
E
V
L
Q
R
L
L
S
E
R
V
S
V
R
N
M
K
L
I
M
E
A
L
A
L
W
A
P
R
E
-
K
D
V
I
N
L
V
E
H
---
I
R
G
A
M
A
R
Y
I
C
H
K
F
A
N
G
G
E
-
L
R
A
V
M
V
S
A
E
V
E
D
V
I
R
K
G
I
R
Q
T
S
G
S
T
F
L
S
L
D
P
E
A
S
A
--
N
L
M
D
L
I
T
L
K
L
D
D
L
L
I
A
H
K
D
L
--
V
-
L
L
T
S
V
D
V
-------
R
R
F
I
K
K
M
I
E
G
R
F
P
D
L
E
V
L
S
F
G
E
I
A
D
S
K
S
V
N
V
I
K
T
I
--
27
Fugue
50.84
15%
-83
- C2 -
4R12
6
?
A:
[15-587]
YTTLYSSYPC
T
K
I
M
T
SD
G
Q
F
G
C
S
S
K
H
G
G
N
S
G
I
L
Y
L
I
D
D
D
E
S
Y
N
N
Y
F
S
Y
S
Q
Q
K
D
I
I
V
V
L
D
T
N
Y
F
N
S
T
S
V
L
N
L
H
N
K
S
K
I
E
----
G
I
I
V
L
T
D
T
K
K
T
Y
P
Y
S
P
D
-
S
R
Y
P
N
K
I
Y
G
L
Y
P
N
S
N
L
E
W
N
P
N
A
D
---
G
F
T
Y
F
S
F
P
F
P
I
-
F
A
I
D
N
Q
T
S
V
A
I
R
N
V
S
K
H
N
R
D
G
Q
Y
P
A
W
G
A
E
L
D
S
F
M
Q
G
A
I
N
S
E
T
C
L
R
R
G
F
C
E
P
V
G
G
Q
S
I
W
S
S
F
S
S
-----
K
I
D
K
E
K
E
I
I
L
V
M
L
P
F
----------------
D
T
T
A
F
F
R
D
L
S
I
G
A
D
Q
S
S
F
A
T
V
T
L
L
S
V
I
K
S
L
A
A
V
D
R
S
S
--------------
W
N
K
E
V
V
F
A
F
W
N
A
E
R
W
G
Y
-----
V
G
S
E
Y
F
I
N
D
L
L
N
F
Q
C
K
T
Y
N
S
D
K
S
K
C
I
D
P
P
R
A
D
L
A
F
Q
T
Q
I
N
F
T
K
-
I
S
T
I
I
E
L
N
Q
I
G
R
A
Q
L
D
K
N
L
G
K
Y
S
L
Y
L
H
T
A
G
T
K
T
S
--
S
V
T
D
I
L
D
Q
V
A
S
S
Y
E
N
S
T
I
----
T
F
K
P
T
T
Q
T
---------
E
L
P
P
S
S
S
M
S
F
L
K
K
T
N
K
I
-
P
V
V
V
I
T
D
H
D
Y
K
Y
S
-----------------
N
P
Y
Y
G
Y
E
Q
D
-------
D
N
E
N
V
L
G
S
T
L
N
D
I
V
Y
I
L
S
T
F
I
D
R
I
A
G
-------
G
N
N
N
I
T
I
D
K
N
F
I
N
I
L
Y
P
C
F
T
S
S
--------
I
T
C
F
------------
N
I
L
M
K
T
Y
P
L
N
E
V
P
N
F
Y
S
S
V
F
G
T
S
L
T
T
-
T
L
S
P
Y
E
T
K
L
---
I
H
R
L
L
Y
S
-
I
T
Q
Y
N
S
T
L
T
N
C
T
S
D
N
D
C
P
S
S
L
C
Y
S
G
Q
C
V
S
S
N
T
H
L
H
N
A
L
S
L
G
F
D
F
D
T
--
S
-----------------------------------------
K
N
V
W
K
I
V
N
S
S
Y
P
I
----
F
T
E
S
N
W
D
Y
T
A
L
K
V
F
K
I
18
HHSearch
38.50
36%
-122
- C1 -
2JOB
-
?
A:
[85-98]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
F
Q
K
G
L
I
S
Q
Q
E
A
N
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
36.54
19%
-122
- C- -
4GR2
-
?
A:
[16-90]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
H
L
H
D
F
F
T
Y
V
A
V
R
I
V
S
A
Q
L
E
S
Y
N
P
E
A
Y
M
E
--------
L
R
--------------
E
F
L
-
D
T
N
S
V
S
D
G
D
K
F
L
A
T
L
M
R
R
S
S
R
H
-
M
N
---
L
A
L
R
I
L
E
V
R
S
A
Y
A
K
N
D
--------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
36.37
23%
-101
- C3 -
3LW9
-
INVA_SALTY
A:
[384-520]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
S
Q
F
F
I
D
Y
G
V
R
L
----
P
E
V
L
L
R
D
G
---------
E
G
L
D
D
N
S
I
V
L
L
I
N
E
I
R
V
E
Q
F
T
V
Y
F
D
--
L
M
R
V
V
N
Y
S
D
E
V
V
S
F
G
I
-
N
P
T
I
H
Q
Q
G
S
S
Q
Y
F
W
V
T
H
E
E
G
E
K
L
R
E
M
G
Y
V
L
R
N
A
L
D
E
L
Y
H
C
L
A
V
T
L
A
R
N
V
N
E
Y
F
G
I
Q
E
T
K
H
M
L
D
Q
L
E
A
K
F
P
D
L
L
K
E
--------
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
35.53
16%
-186
- C3 -
2KVC
-
?
A:
[8-88]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
S
I
V
A
W
L
R
A
G
Y
P
E
G
I
P
P
TD
S
F
A
V
L
A
L
L
C
R
R
L
S
H
D
E
V
K
A
V
A
N
E
L
M
R
L
G
-
D
F
-
D
Q
I
D
I
G
V
V
I
T
H
F
T
D
E
L
-
P
S
P
E
-
D
V
E
R
---
V
R
A
R
L
A
A
----------------------------------------------------------------------------------------------------------------------------
16
HHSearch
35.41
18%
-184
- C3 -
2LKY
-
?
A:
[10-90]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
K
I
A
A
W
L
N
A
G
Y
P
E
G
V
P
G
P
D
R
V
P
L
L
A
L
L
T
R
R
L
T
N
D
E
I
K
A
I
A
E
D
L
E
K
R
A
-
H
F
-
D
H
I
D
I
G
V
L
I
T
Q
M
T
D
E
M
-
P
R
-
E
E
D
I
E
R
---
V
R
R
H
L
A
L
----------------------------------------------------------------------------------------------------------------------------
14
HHSearch
34.47
13%
-184
- C3 -
4X86
3
A:
[5-54]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
V
W
Q
L
I
S
K
V
L
A
R
H
F
S
A
A
D
A
S
R
V
L
E
Q
L
Q
R
D
Y
E
R
S
L
-------------
S
R
L
T
L
D
D
I
E
R
L
A
S
R
F
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
24.64
26%
77
- C3 -
3BPQ
-
RELB3_METJA
A:
[8-48]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
F
F
I
S
R
K
E
-
Y
E
K
I
E
E
I
L
D
I
G
L
A
K
A
M
E
E
T
K
D
D
--
E
L
L
T
Y
D
E
I
K
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
21.95
12%
-77
- C3 -
3T7Z
3
Y694_METJA
A:
[1-119]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
Y
V
T
F
T
P
Y
G
A
F
G
V
K
D
N
K
E
V
S
G
L
-
E
D
I
E
Y
K
K
L
F
N
E
E
E
I
P
D
I
M
F
K
L
K
T
Q
P
N
K
I
A
D
E
L
K
E
E
W
G
D
E
I
K
L
E
T
L
S
T
E
P
F
N
I
G
--
E
F
L
R
N
N
L
F
K
V
G
K
E
L
G
Y
F
N
----
N
Y
D
E
F
R
K
K
---------
M
H
Y
W
S
T
E
L
T
K
K
V
I
K
S
Y
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
21.27
25%
-52
- C3 -
2LVH
1
Y059A_AFV1Y
A:
[7-50]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
E
R
V
Y
Q
C
L
R
C
G
L
T
F
R
T
K
K
Q
L
I
R
H
L
V
N
T
-----
E
K
--------
V
N
P
L
S
I
D
Y
Y
Y
Q
S
F
S
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
21.19
10%
-68
- C3 -
2KHZ
-
DNPH1_RAT
A:
[1-163]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
A
S
G
E
Q
A
P
C
S
V
Y
F
C
G
S
I
R
G
G
R
E
D
Q
A
L
-
Y
A
R
I
V
S
R
L
R
R
Y
G
K
V
L
T
E
H
V
A
D
A
E
L
E
P
L
G
E
E
A
A
G
G
D
Q
F
I
H
E
Q
D
L
N
W
L
Q
Q
A
D
V
V
V
--
A
E
V
T
Q
P
S
L
G
V
G
Y
E
L
G
R
A
V
A
LGK
P
I
L
C
L
F
R
P
QSGRVLS
A
M
I
R
G
A
A
D
G
S
R
F
Q
V
W
D
Y
A
E
G
E
V
E
T
M
L
D
R
Y
F
E
A
Y
L
P
Q
K
T
A
S
S
S
-
H
P
-
S
-
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------