@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu16660: (2016-06-26 )
MVNGVLLLHKPVGMTSHDCVMKIRKLLKTKKVGHTGTLDPEVSGVLPICVGRATKIVEYLTEKSKTYDAEITLGFSTTTEDQTGETVETKPVNHDIDKADVEKVLNSLKGKQEQIPPMYSAVKVNGKKLYEYARAGIEVERPKRMITIEDIALTTEIKHHGETASFRFTVTCSKGTYVRTLAVMIGEKLGYPAHMSHLIRTASGDFSLDECFTFDELEAQAQSGTVEEHTVPIERALNHLPKWIISDTLAKKVENGALLETPEQFSEMTSGDRIAVFTESGTCLAIYFPHPAKKGLLKPAKVLMQKSEQ
Atome Classification :
(26 SA)
-.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......-210..-----......220------.---------...---------....----230.......240.......250......--.260---......--.---270......--.280......--.290..--------.------....300.......---
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-MV
N
G
V
L
L
L
HKPVGMT
S
H
D
C
V
M
K
I
R
K
L
L
K
TKKVGHTGTLDPEVSG
V
L
P
ICVG
R
A
T
K
I
V
E
Y
L
T
E
KSKTY
D
A
E
I
T
L
G
F
STTTEDQTGETVETKPVNHDI
D
K
A
D
V
E
K
V
L
N
SLKGKQEQIPP
M
Y
S
A
V
KV
N
G
K
K
L
Y
E
Y
A
R
AG
I
E
VERP
K
R
M
I
T
I
E
D
I
A
L
T
T
E
IKHHGET
A
S
F
R
F
T
V
T
CSKG
T
Y
V
R
T
L
A
V
M
I
G
EKLGY
P
A
H
M
S
H
L
I
R
TASGDF
S
L
D
-
E
C-F
T
-----
F
D
E
L
E
A
Q
A-------Q---------SGT---------VEEH----T
V
P
I
E
R
A
L
N
HL
P
K
W
I
I
S
D
T
L
A
K
K
VENGAL--LE
T
P
---
E
Q
F
S
EM--T---SG
D
R
I
A
V
F
T--ESG
T
C
L
A
I
YF--PHPAKK--------G------L
L
K
P
A
K
V
L
M
QKSEQ---
49
Fugue
86.88
34%
-106
- C6 -
1R3E
3
TRUB_THEMA
A:
[1-309]
-
M
K
H
G
I
L
V
A
Y
K
P
K
G
P
T
S
H
D
V
V
D
E
V
R
K
K
L
K
T
R
K
V
G
H
G
G
T
L
D
P
F
A
C
G
V
L
I
I
G
V
N
Q
G
T
R
I
L
E
F
Y
K
D
L
K
K
V
Y
W
V
K
M
R
L
G
L
I
T
E
T
F
D
I
T
G
E
V
V
E
E
R
E
C
N
--
V
T
E
E
E
I
R
E
A
I
F
S
F
V
G
E
Y
D
Q
V
P
P
A
Y
S
A
K
K
Y
K
G
E
R
L
Y
K
L
A
R
E
G
K
I
I
N
L
P
P
K
R
V
K
I
F
K
I
W
D
V
N
I
-----
E
G
R
D
V
S
F
R
V
E
V
S
P
G
T
Y
I
R
S
L
C
M
D
I
G
Y
K
L
G
C
G
A
T
A
V
E
L
V
R
E
S
V
G
P
H
T
I
E
-
E
S
-
L
N
-----
V
F
E
A
A
--------------------
P
E
E
---------
I
E
N
R
----
I
I
P
L
E
K
C
L
E
W
L
P
R
V
V
V
H
Q
E
S
T
K
M
I
L
N
G
S
Q
--
I
H
L
E
ML-
K
E
W
D
G
F
--
K
---
K
G
E
V
V
R
V
F
N
--
E
E
G
R
L
L
A
L
A
E
A
E
R
N
S
S
F
L
--------
E
------
T
L
R
K
E
R
V
L
T
L
R
K
V
F
NTR
6
PsiBlast_PDB
85.74
36%
-102
- C6 -
1R3E
3
TRUB_THEMA
A:
[1-281]
-
M
K
H
G
I
L
V
A
Y
K
P
K
G
P
T
S
H
D
V
V
D
E
V
R
K
K
L
K
T
R
K
V
G
H
G
G
T
L
D
P
F
A
C
G
V
L
I
I
G
V
N
Q
G
T
R
I
L
E
F
Y
K
D
L
K
K
V
Y
W
V
K
M
R
L
G
L
I
T
E
T
F
D
I
T
G
E
V
V
E
E
R
E
C
N
--
V
T
E
E
E
I
R
E
A
I
F
S
F
V
G
E
Y
D
Q
V
P
P
A
Y
S
A
K
K
Y
K
G
E
R
L
Y
K
L
A
R
E
G
K
I
I
N
L
P
P
K
R
V
K
I
F
K
I
W
---
D
V
N
I
E
G
R
D
V
S
F
R
--
V
E
V
S
P
G
T
Y
I
R
S
L
C
M
D
I
G
Y
K
L
G
C
G
A
T
A
V
E
L
V
R
E
S
V
G
P
H
T
I
E
-
E
S
-
L
N
-----
V
F
E
----
A
-------
A
---------
P
E
E
---------
I
E
N
R
----
I
I
P
L
E
K
C
L
E
W
L
P
R
V
V
V
H
Q
E
S
T
K
M
I
L
N
G
S
Q
IH
L
E
M
L
---
K
E
W
D
G
F
--
K
---
K
G
E
V
V
R
V
F
N
--
E
E
G
R
L
L
A
L
------------------------------------------
7
PsiBlast_PDB
85.51
36%
-110
- C6 -
2AB4
2
TRUB_THEMA
A:
[1-285]
-
M
K
H
G
I
L
V
A
Y
K
P
K
G
P
T
S
H
D
V
V
D
E
V
R
K
K
L
K
T
R
K
V
G
H
G
G
T
L
D
P
F
A
C
G
V
L
I
I
G
V
N
Q
G
T
R
I
L
E
F
Y
K
D
L
K
K
V
F
W
V
K
M
R
L
G
L
I
T
E
T
F
D
I
T
G
E
V
V
E
E
R
E
C
N
--
V
T
E
E
E
I
R
E
A
I
F
S
F
V
G
E
Y
D
Q
V
P
P
A
Y
S
A
K
K
Y
K
G
E
R
L
Y
K
L
A
R
E
G
K
I
I
N
L
P
P
K
R
V
K
I
F
K
I
W
---
D
V
N
I
E
G
R
D
V
S
F
R
--
V
E
V
S
P
G
T
Y
I
R
S
L
C
M
D
I
G
Y
K
L
G
C
G
A
T
A
V
E
L
V
R
E
S
V
G
P
H
T
I
E
-
E
S
-
L
N
-----
V
F
E
----
A
-------
A
---------
P
E
E
---------
I
E
N
R
----
I
I
P
L
E
K
C
L
E
W
L
P
R
V
V
V
H
Q
E
S
T
K
M
I
L
N
G
S
Q
I
H
L
E
M
L
---
K
E
W
D
G
F
--
K
---
K
G
E
V
V
R
V
F
N
--
E
E
G
R
L
L
A
L
------------------------------------------
57
HHSearch
85.43
33%
-106
- C6 -
1R3E
3
TRUB_THEMA
A:
[1-305]
-
M
K
H
G
I
L
V
A
Y
K
P
K
G
P
T
S
H
D
V
V
D
E
V
R
K
K
L
K
T
R
K
V
G
H
G
G
T
L
D
P
F
A
C
G
V
L
I
I
G
V
N
Q
G
T
R
I
L
E
F
Y
K
D
L
K
K
V
Y
W
V
K
M
R
L
G
L
I
T
E
T
F
D
I
T
G
E
V
V
E
E
R
E
--
C
N
V
T
E
E
E
I
R
E
A
I
F
S
F
V
G
E
Y
D
Q
V
P
P
A
Y
S
A
K
K
Y
K
G
E
R
L
Y
K
L
A
R
E
G
K
I
I
N
L
P
P
K
R
V
K
I
F
K
I
W
D
V
N
I
E
G
-----
R
D
V
S
F
R
V
E
V
S
P
G
T
Y
I
R
S
L
C
M
D
I
G
Y
K
L
G
C
G
A
T
A
V
E
L
V
R
E
S
V
G
P
H
T
I
E
-
E
S
-
L
N
-----
V
F
E
A
A
P
E
E
-----------------------------
I
E
N
R
----
I
I
P
L
E
K
C
L
E
W
L
P
R
V
V
V
H
Q
E
S
T
K
M
I
L
N
G
S
Q
--
I
H
L
E
---
M
L
K
E
W
D
GF
K
---
K
G
E
V
V
R
V
F
N
E-
E
G
R
-
L
L
A
L
A
E
--
A
E
R
N
S
S
--------
F
LETLRK----
E
R
V
L
T
L
R
K
V
----
47
Fugue
84.64
35%
-95
- C6 -
1K8W
11
TRUB_ECOLI
A:
[22-324]
M
D
I
N
G
V
L
L
L
D
K
P
Q
G
M
S
S
N
D
A
L
Q
K
V
K
R
I
Y
N
A
N
R
A
G
H
T
G
A
L
D
P
L
A
T
G
M
L
P
I
C
L
G
E
A
T
K
F
S
Q
Y
L
L
D
S
D
K
R
Y
R
V
I
A
R
L
G
Q
R
T
D
T
S
D
A
D
G
Q
I
V
E
E
R
P
V
T
--
F
S
A
E
Q
L
A
A
A
L
D
T
F
R
G
D
I
E
Q
I
P
S
M
Y
S
A
L
K
Y
Q
G
K
K
L
Y
E
Y
A
R
Q
G
I
E
V
P
R
E
A
R
P
I
T
V
Y
E
L
L
F
I
R
H
E
G
N
-----
E
L
E
L
E
I
H
C
S
K
G
T
Y
I
R
T
I
I
D
D
L
G
E
K
L
G
C
G
A
H
V
I
Y
L
R
R
L
A
V
S
K
Y
P
V
E
-
R
M
-
V
T
-----
L
E
H
L
R
E
L
V
-------
E
---------
Q
A
E
Q
Q
DIP
A
A
E
L
L
D
P
L
----
L
M
P
M
D
S
P
A
S
D
Y
P
V
V
N
L
P
L
T
S
S
V
Y
F
K
N
G
N
------
P
---
V
R
T
S
G
A
--
P
---
L
E
G
L
V
R
V
T
E
G
-
E
N
G
K
F
I
G
M
G
E
--
I
D
D
--
E
--------
G
------
R
V
A
P
R
R
L
V
V
E
-------
5
PsiBlast_PDB
84.56
36%
-108
- C6 -
1ZE2
2
TRUB_THEMA
A:
[1-285]
-
M
K
H
G
I
L
V
A
Y
K
P
K
G
P
T
S
H
D
V
V
D
E
V
R
K
K
L
K
T
R
K
V
G
H
G
G
T
L
D
P
F
A
C
G
V
L
I
I
G
V
N
Q
G
T
R
I
L
E
F
Y
K
D
L
K
K
V
Y
W
V
K
M
R
L
G
L
I
T
E
T
F
D
I
T
G
E
V
V
E
E
R
E
C
N
--
V
T
E
E
E
I
R
E
A
I
F
S
F
V
G
E
Y
D
Q
V
P
P
A
Y
S
A
K
K
Y
K
G
E
R
L
Y
K
L
A
R
E
G
K
I
I
N
L
P
P
K
R
V
K
I
F
K
I
W
---
D
V
N
I
E
G
R
D
V
S
F
R
--
V
E
V
S
P
G
T
Y
I
R
S
L
C
M
D
I
G
Y
K
L
G
C
G
A
T
A
V
E
L
V
R
E
S
V
G
P
H
T
I
E
-
E
S
-
L
N
-----
V
F
E
----
A
-------
A
---------
P
E
E
---------
I
E
N
R
----
I
I
P
L
E
K
C
L
E
W
L
P
R
V
V
V
H
Q
E
S
T
K
M
I
L
N
G
S
Q
I
H
L
E
M
L
---
K
E
W
D
G
F
--
K
---
K
G
E
V
V
R
V
F
N
--
E
E
G
R
L
L
A
L
------------------------------------------
4
PsiBlast_PDB
84.38
36%
-102
- C6 -
1ZE1
1
TRUB_THEMA
A:
[1-277]
-
M
K
H
G
I
L
V
A
Y
K
P
K
G
P
T
S
H
D
V
V
D
E
V
R
K
K
L
K
T
R
K
V
G
H
G
G
T
L
D
P
F
A
C
G
V
L
I
I
G
V
N
Q
G
T
R
I
L
E
F
Y
K
D
L
K
K
V
Y
W
V
K
M
R
L
G
L
I
T
E
T
F
D
I
T
G
E
V
V
E
E
R
E
C
N
--
V
T
E
E
E
I
R
E
A
I
F
S
F
V
G
E
Y
D
Q
V
P
P
A
Y
S
A
K
K
Y
K
G
E
R
L
Y
K
L
A
R
E
G
K
I
I
N
L
P
P
K
R
V
K
I
F
K
I
W
---
D
V
N
I
E
G
R
D
V
S
F
R
--
V
E
V
S
P
G
T
Y
I
R
S
L
C
M
D
I
G
Y
K
L
G
C
G
A
T
A
V
E
L
V
R
E
S
V
G
P
H
T
I
E
-
E
S
-
L
N
-----
V
F
E
----
A
-------
A
---------
P
E
E
---------
I
E
N
R
----
I
I
P
L
E
K
C
L
E
W
L
P
R
V
V
V
H
Q
E
S
T
K
M
I
L
N
G
S
Q
I
H
L
E
M
L
---
K
E
W
D
G
F
--
K
---
K
G
E
V
V
R
V
F
N
--
E
E
G
R
L
L
A
L
------------------------------------------
58
HHSearch
84.06
34%
-97
- C6 -
1K8W
11
TRUB_ECOLI
A:
[24-325]
--
I
N
G
V
L
L
L
D
K
P
Q
G
M
S
S
N
D
A
L
Q
K
V
K
R
I
Y
N
A
N
R
A
G
H
T
G
A
L
D
P
L
A
T
G
M
L
P
I
C
L
G
E
A
T
K
F
S
Q
Y
L
L
D
S
D
K
R
Y
R
V
I
A
R
L
G
Q
R
T
D
T
S
D
A
D
G
Q
I
V
E
E
R
P
V
--
T
F
S
A
E
Q
L
A
A
A
L
D
T
F
R
G
D
I
E
Q
I
P
S
M
Y
S
A
L
K
Y
Q
G
K
K
L
Y
E
Y
A
R
Q
G
I
E
V
P
R
E
A
R
P
I
T
V
Y
E
L
L
F
I
R
H
E
G
-----
N
E
L
E
L
E
I
H
C
S
K
G
T
Y
I
R
T
I
I
D
D
L
G
E
K
L
G
C
G
A
H
V
I
Y
L
R
R
L
A
V
S
K
Y
P
V
E
-
R
M
-
V
T
-----
L
E
H
L
R
E
L
V
-------
E
Q
A
E
Q
Q
DIP
A
A
E
L
---------
L
D
P
L
----
L
M
P
M
D
S
P
A
S
D
Y
P
V
V
N
L
P
L
T
S
S
V
Y
F
K
N
G
N
P
--
V
R
T
S
---
G
A
P
---------
L
E
G
L
V
R
V
T
E
G
E
N
G
K
-
F
I
G
M
G
E
--
I
D
D
E
----------
G
------
R
V
A
P
R
R
L
V
V
E
Y
------
23
PsiBlast_CBE
83.18
36%
-99
- C6 -
1ZE1
1
TRUB_THEMA
B:
[1-277]
-
M
K
H
G
I
L
V
A
Y
K
P
K
G
P
T
S
H
D
V
V
D
E
V
R
K
K
L
K
T
R
K
V
G
H
G
G
T
L
D
P
F
A
C
G
V
L
I
I
G
V
N
Q
G
T
R
I
L
E
F
Y
K
D
L
K
K
V
Y
W
V
K
M
R
L
G
L
I
T
E
T
F
D
I
T
G
E
V
V
E
E
R
E
C
N
--
V
T
E
E
E
I
R
E
A
I
F
S
F
V
G
E
Y
D
Q
V
P
P
A
Y
S
A
K
K
Y
K
G
E
R
L
Y
K
L
A
R
E
G
K
I
I
N
L
P
P
K
R
V
K
I
F
K
I
W
---
D
V
N
I
E
G
R
D
V
S
F
R
--
V
E
V
S
P
G
T
Y
I
R
S
L
C
M
D
I
G
Y
K
L
G
C
G
A
T
A
V
E
L
V
R
E
S
V
G
P
H
T
I
E
-
E
S
-
L
N
-----
V
F
E
----
A
-------
A
---------
P
E
E
---------
I
E
N
R
----
I
I
P
L
E
K
C
L
E
W
L
P
R
V
V
V
H
Q
E
S
T
K
M
I
L
N
G
S
Q
IH
L
E
M
L
---
K
E
W
D
G
F
--
K
---
K
G
E
V
V
R
V
F
N
--
E
E
G
R
L
L
A
L
------------------------------------------
22
PsiBlast_CBE
83.02
36%
-95
- C6 -
1ZE1
1
TRUB_THEMA
C:
[1-277]
-
M
K
H
G
I
L
V
A
Y
K
P
K
G
P
T
S
H
D
V
V
D
E
V
R
K
K
L
K
T
R
K
V
G
H
G
G
T
L
D
P
F
A
C
G
V
L
I
I
G
V
N
Q
G
T
R
I
L
E
F
Y
K
D
L
K
K
V
Y
W
V
K
M
R
L
G
L
I
T
E
T
F
D
I
T
G
E
V
V
E
E
R
E
C
N
--
V
T
E
E
E
I
R
E
A
I
F
S
F
V
G
E
Y
D
Q
V
P
P
A
Y
S
A
K
K
Y
K
G
E
R
L
Y
K
L
A
R
E
G
K
I
I
N
L
P
P
K
R
V
K
I
F
K
I
W
---
D
V
N
I
E
G
R
D
V
S
F
R
--
V
E
V
S
P
G
T
Y
I
R
S
L
C
M
D
I
G
Y
K
L
G
C
G
A
T
A
V
E
L
V
R
E
S
V
G
P
H
T
I
E
-
E
S
-
L
N
-----
V
F
E
----
A
-------
A
---------
P
E
E
---------
I
E
N
R
----
I
I
P
L
E
K
C
L
E
W
L
P
R
V
V
V
H
Q
E
S
T
K
M
I
L
N
G
S
Q
IH
L
E
M
L
---
K
E
W
D
G
F
--
K
---
K
G
E
V
V
R
V
F
N
--
E
E
G
R
L
L
A
L
------------------------------------------
9
PsiBlast_PDB
81.62
32%
-129
- C6 -
2AUS
2
TRUB_PYRAB
C:
[47-299]
----
G
V
I
N
L
D
K
P
P
G
P
T
S
H
E
V
V
A
W
I
K
R
I
L
N
L
E
K
A
G
H
G
G
T
L
D
P
K
V
S
G
V
L
P
V
A
L
E
R
A
T
R
V
V
Q
A
L
L
P
A
G
K
E
Y
V
A
L
M
H
L
-------------------
H
G
D
V
P
E
D
K
I
R
A
V
M
K
E
F
E
G
E
I
I
Q
R
--------------------------
T
R
K
V
Y
Y
I
E
I
L
E
I
D
------
G
R
D
V
L
F
R
V
G
V
E
A
--
G
T
Y
I
R
S
L
I
H
H
I
G
L
A
L
G
V
G
A
H
M
A
E
L
R
R
T
R
S
G
P
F
K
E
D
-
E
T
-
L
V
T
L
H
D
L
V
D
Y
Y
H
F
W
K
-------
E
---------
D
G
----------
I
E
E
Y
I
R
K
A
I
Q
P
M
E
K
A
V
E
H
L
P
K
I
W
I
K
D
S
A
V
A
A
V
A
H
G
A
N
--
L
T
V
P
GIV
K
L
N
A
G
I
--
K
---
K
G
D
L
V
A
I
M
T
--
L
K
D
E
L
V
A
L
------------------------------------------
62
HHSearch
81.39
36%
-139
* C6 *
2AUS
2
TRUB_PYRAB
C:
[45-305]
--
Q
Y
G
V
I
N
L
D
K
P
P
G
P
T
S
H
E
V
V
A
W
I
K
R
I
L
N
L
E
K
A
G
H
G
G
T
L
D
P
K
V
S
G
V
L
P
V
A
L
E
R
A
T
R
V
V
Q
A
L
L
P
A
G
K
E
Y
V
A
L
M
H
L
H
G
-------------------
D
V
P
E
D
K
I
R
A
V
M
K
E
F
E
G
E
I
I
Q
R
-----------------------------
T
R
K
V
Y
Y
I
E
I
L
E
I
D
G
-----
R
D
V
L
F
R
V
G
V
E
A
G
T
Y
I
R
S
L
I
H
H
I
G
L
A
L
G
V
G
A
H
M
A
E
L
R
R
T
R
S
G
P
F
K
E
D
-
E
T
L
V
T
-----
L
H
D
L
V
D
Y
Y
H
F
W
KEDG
I
---------
E
E
Y
---------
I
R
K
A
----
I
Q
P
M
E
K
A
V
E
H
L
P
K
I
W
I
K
D
S
A
V
A
A
V
A
H
G
A
N
--
L
T
V
P
---
G
I
V
K
L
N
--
A
GIK
K
G
D
L
V
A
I
M
T
L-
K
D
E
-
L
V
A
L
G
K
--
A
M
M
S
----------------------------------
21
PsiBlast_CBE
81.19
36%
-105
- C6 -
1ZE1
1
TRUB_THEMA
D:
[1-277]
-
M
K
H
G
I
L
V
A
Y
K
P
K
G
P
T
S
H
D
V
V
D
E
V
R
K
K
L
K
T
R
K
V
G
H
G
G
T
L
D
P
F
A
C
G
V
L
I
I
G
V
N
Q
G
T
R
I
L
E
F
Y
K
D
L
K
K
V
Y
W
V
K
M
R
L
G
L
I
T
E
T
F
D
I
T
G
E
V
V
E
E
R
E
C
N
--
V
T
E
E
E
I
R
E
A
I
F
S
F
V
G
E
Y
D
Q
V
P
P
A
------------------------
P
K
R
V
K
I
F
K
I
W
---
D
V
N
I
E
G
R
D
V
S
F
R
--
V
E
V
S
P
G
T
Y
I
R
S
L
C
M
D
I
G
Y
K
L
G
C
G
A
T
A
V
E
L
V
R
E
S
V
G
P
H
T
I
E
-
E
S
-
L
N
-----
V
F
E
----
A
-------
A
---------
P
E
E
---------
I
E
N
R
----
I
I
P
L
E
K
C
L
E
W
L
P
R
V
V
V
H
Q
E
S
T
K
M
I
L
N
G
S
Q
IH
L
E
M
L
---
K
E
W
D
G
F
--
K
---
K
G
E
V
V
R
V
F
N
--
E
E
G
R
L
L
A
L
------------------------------------------
25
PsiBlast_CBE
79.23
32%
-134
- C6 -
2AUS
3
TRUB_PYRAB
A:
[47-299]
----
G
V
I
N
L
D
K
P
P
G
P
T
S
H
E
V
V
A
W
I
K
R
I
L
N
L
E
K
A
G
H
G
G
T
L
D
P
K
V
S
G
V
L
P
V
A
L
E
R
A
T
R
V
V
Q
A
L
L
P
A
G
K
E
Y
V
A
L
M
H
L
-------------------
H
G
D
V
P
E
D
K
I
R
A
V
M
K
E
F
E
G
E
I
I
Q
R
----------------------------
K
V
Y
Y
I
E
I
L
E
I
D
------
G
R
D
V
L
F
R
V
G
V
E
A
--
G
T
Y
I
R
S
L
I
H
H
I
G
L
A
L
G
V
G
A
H
M
A
E
L
R
R
T
R
S
G
P
F
K
E
D
-
E
T
-
L
V
T
L
H
D
L
V
D
Y
Y
H
F
W
K
-------
E
---------
D
G
----------
I
E
E
Y
I
R
K
A
I
Q
P
M
E
K
A
V
E
H
L
P
K
I
W
I
K
D
S
A
V
A
A
V
A
H
G
A
N
--
L
T
V
P
GIV
K
L
N
A
G
I
--
K
---
K
G
D
L
V
A
I
M
T
--
L
K
D
E
L
V
A
L
------------------------------------------
15
PsiBlast_PDB
78.62
32%
-134
- C6 -
3LWP
1
TRUB_PYRFU
A:
[47-299]
----
G
V
I
N
L
D
K
P
P
G
P
T
S
H
E
V
V
A
W
I
K
K
I
L
N
L
E
K
A
G
H
G
G
T
L
D
P
K
V
S
G
V
L
P
V
A
L
E
K
A
T
R
V
V
Q
A
L
L
P
A
G
K
E
Y
V
A
L
M
H
L
-------------------
H
G
D
V
P
E
D
K
I
I
Q
V
M
K
E
F
E
G
E
I
I
Q
R
-------------
L
-----------
R
T
R
K
V
Y
Y
I
E
V
L
E
I
--------
E
G
R
D
V
L
F
R
V
G
V
E
A
G
T
Y
I
R
S
L
I
H
H
I
G
L
A
L
G
V
G
A
H
M
S
E
L
R
R
T
R
S
G
P
F
K
E
D
-
E
T
-
L
I
T
L
H
D
L
V
D
Y
Y
Y
F
W
K
-------
E
---------
D
G
----------
I
E
E
Y
F
R
K
A
I
Q
P
M
E
K
A
V
E
H
L
P
K
V
W
I
K
D
S
A
V
A
A
V
T
H
G
A
D
--
L
A
V
P
GIA
K
L
H
A
G
I
--
K
---
R
G
D
L
V
A
I
M
T
--
L
K
D
E
L
V
A
L
------------------------------------------
2
PsiBlast_PDB
78.60
41%
-96
- C6 -
1K8W
8
TRUB_ECOLI
A:
[24-253]
--
I
N
G
V
L
L
L
D
K
P
Q
G
M
S
S
N
D
A
L
Q
K
V
K
R
I
Y
N
A
N
R
A
G
H
T
G
A
L
D
P
L
A
T
G
M
L
P
I
C
L
G
E
A
T
K
F
S
Q
Y
L
L
D
S
D
K
R
Y
R
V
I
A
R
L
G
Q
R
T
D
T
S
D
A
D
G
Q
I
V
E
E
R
P
V
T
F
S
A
E
Q
--
L
A
A
A
L
D
T
F
R
G
D
I
E
Q
I
P
S
M
Y
S
A
L
K
Y
Q
G
K
K
L
Y
E
Y
A
R
Q
G
I
E
V
P
R
E
A
R
P
I
T
V
Y
E
L
L
F
---
I
R
H
E
G
N
--
E
L
E
L
E
I
H
C
S
K
G
T
Y
I
R
T
I
I
D
D
L
G
E
K
L
G
C
G
A
H
V
I
Y
L
R
R
L
A
V
S
K
Y
P
V
E
-
R
M
-
V
T
-----
L
E
H
L
R
E
L
V
-------
E
---------
Q
A
-----------
E
Q
Q
----
D
I
P
A
A
E
L
L
D
P
L
----------------------------------------------------------------------------------------------------
61
HHSearch
78.59
30%
-126
- C6 -
3U28
-
CBF5_YEAST
A:
[58-342]
--
S
S
G
V
I
N
L
D
K
P
S
N
P
S
S
H
E
V
V
A
W
I
K
R
I
L
R
C
E
K
T
G
H
S
G
T
L
D
P
K
V
T
G
C
L
I
V
C
I
D
R
A
T
R
L
V
K
S
Q
Q
G
A
G
K
E
Y
V
C
I
V
R
L
H
D
A
L
K
------------------
D
E
K
D
L
G
R
S
L
E
N
L
T
G
A
L
F
Q
R
P
P
-----
K
R
Q
-----------------
L
R
V
R
T
I
Y
E
S
N
L
I
E
F
D
N
K
---
R
N
L
G
V
F
W
A
S
C
E
A
G
T
Y
M
R
T
L
C
V
H
L
G
M
L
L
G
V
G
G
H
M
Q
E
L
R
R
V
R
S
G
A
L
S
E
N
D
N
M
-
V
T
-----
L
H
D
V
M
D
A
Q
W
V
Y
D
N
TR
D
---------
E
S
Y
---------
L
R
S
I
----
I
Q
P
L
E
T
L
L
V
G
Y
K
R
I
V
V
K
D
S
A
V
N
A
V
C
Y
G
A
K
--
L
M
I
P
---
G
L
L
R
Y
E
--
E
GIE
L
Y
D
E
I
V
L
I
T
T-
K
G
E
-
A
I
A
V
A
I
--
A
Q
M
S
T
V
D
L
A
S
CDHG
V
------
V
A
S
V
K
R
C
I
M
E
-------
3
PsiBlast_PDB
77.52
40%
-95
- C6 -
1ZL3
3
TRUB_ECOLI
A:
[24-253]
--
I
N
G
V
L
L
L
D
K
P
Q
G
M
S
S
N
D
A
L
Q
K
V
K
R
I
Y
N
A
N
R
A
G
H
T
G
A
L
N
P
L
A
T
G
M
L
P
I
C
L
G
E
A
T
K
F
S
Q
Y
L
L
D
S
D
K
R
Y
R
V
I
A
R
L
G
Q
R
T
D
T
S
D
A
D
G
Q
I
V
E
E
R
P
V
T
F
S
A
E
Q
--
L
A
A
A
L
D
T
F
R
G
D
I
E
Q
I
P
S
M
Y
S
A
L
K
Y
Q
G
K
K
L
Y
E
Y
A
R
Q
G
I
E
V
P
R
E
A
R
P
I
T
V
Y
E
L
L
F
---
I
R
H
E
G
N
--
E
L
E
L
E
I
H
C
S
K
G
T
Y
I
R
T
I
I
D
D
L
G
E
K
L
G
C
G
A
H
V
I
Y
L
R
R
L
A
V
S
K
Y
P
V
E
-
R
M
-
V
T
-----
L
E
H
L
R
E
L
V
-------
E
---------
Q
A
-----------
E
Q
Q
----
D
I
P
A
A
E
L
L
D
P
L
----------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
77.48
32%
-127
- C6 -
3LWO
1
TRUB_PYRFU
A:
[47-299]
----
G
V
I
N
L
D
K
P
P
G
P
T
S
H
E
V
V
A
W
I
K
K
I
L
N
L
E
K
A
G
H
G
G
T
L
D
P
K
V
S
G
V
L
P
V
A
L
E
K
A
T
R
V
V
Q
A
L
L
P
A
G
K
E
Y
V
A
L
M
H
L
-------------------
H
G
D
V
P
E
D
K
I
I
Q
V
M
K
E
F
E
G
E
I
I
Q
R
-------------
L
-----------
R
T
R
K
V
Y
Y
I
E
V
L
E
I
--------
E
G
R
D
V
L
F
R
V
G
V
E
A
G
T
Y
I
R
S
L
I
H
H
I
G
L
A
L
G
V
G
A
H
M
S
E
L
R
R
T
R
S
G
P
F
K
E
D
-
E
T
-
L
I
T
L
H
D
L
V
D
Y
Y
Y
F
W
K
-------
E
---------
D
G
----------
I
E
E
Y
F
R
K
A
I
Q
P
M
E
K
A
V
E
H
L
P
K
V
W
I
K
D
S
A
V
A
A
V
T
H
G
A
D
--
L
A
V
P
GIA
K
L
H
A
G
I
--
K
---
R
G
D
L
V
A
I
M
T
--
L
K
D
E
L
V
A
L
------------------------------------------
17
PsiBlast_PDB
77.37
32%
-127
- C6 -
3LWR
1
TRUB_PYRFU
A:
[47-299]
----
G
V
I
N
L
D
K
P
P
G
P
T
S
H
E
V
V
A
W
I
K
K
I
L
N
L
E
K
A
G
H
G
G
T
L
D
P
K
V
S
G
V
L
P
V
A
L
E
K
A
T
R
V
V
Q
A
L
L
P
A
G
K
E
Y
V
A
L
M
H
L
-------------------
H
G
D
V
P
E
D
K
I
I
Q
V
M
K
E
F
E
G
E
I
I
Q
R
-------------
L
-----------
R
T
R
K
V
Y
Y
I
E
V
L
E
I
--------
E
G
R
D
V
L
F
R
V
G
V
E
A
G
T
Y
I
R
S
L
I
H
H
I
G
L
A
L
G
V
G
A
H
M
S
E
L
R
R
T
R
S
G
P
F
K
E
D
-
E
T
-
L
I
T
L
H
D
L
V
D
Y
Y
Y
F
W
K
-------
E
---------
D
G
----------
I
E
E
Y
F
R
K
A
I
Q
P
M
E
K
A
V
E
H
L
P
K
V
W
I
K
D
S
A
V
A
A
V
T
H
G
A
D
--
L
A
V
P
GIA
K
L
H
A
G
I
--
K
---
R
G
D
L
V
A
I
M
T
--
L
K
D
E
L
V
A
L
------------------------------------------
18
PsiBlast_PDB
76.54
32%
-127
- C6 -
3LWV
1
TRUB_PYRFU
A:
[47-299]
----
G
V
I
N
L
D
K
P
P
G
P
T
S
H
E
V
V
A
W
I
K
K
I
L
N
L
E
K
A
G
H
G
G
T
L
D
P
K
V
S
G
V
L
P
V
A
L
E
K
A
T
R
V
V
Q
A
L
L
P
A
G
K
E
Y
V
A
L
M
H
L
-------------------
H
G
D
V
P
E
D
K
I
I
Q
V
M
K
E
F
E
G
E
I
I
Q
R
-------------
L
-----------
R
T
R
K
V
Y
Y
I
E
V
L
E
I
--------
E
G
R
D
V
L
F
R
V
G
V
E
A
G
T
Y
I
R
S
L
I
H
H
I
G
L
A
L
G
V
G
A
H
M
S
E
L
R
R
T
R
S
G
P
F
K
E
D
-
E
T
-
L
I
T
L
H
D
L
V
D
Y
Y
Y
F
W
K
-------
E
---------
D
G
----------
I
E
E
Y
F
R
K
A
I
Q
P
M
E
K
A
V
E
H
L
P
K
V
W
I
K
D
S
A
V
A
A
V
T
H
G
A
D
--
L
A
V
P
GIA
K
L
H
A
G
I
--
K
---
R
G
D
L
V
A
I
M
T
--
L
K
D
E
L
V
A
L
------------------------------------------
16
PsiBlast_PDB
76.34
32%
-127
- C6 -
3LWQ
1
TRUB_PYRFU
A:
[47-299]
----
G
V
I
N
L
D
K
P
P
G
P
T
S
H
E
V
V
A
W
I
K
K
I
L
N
L
E
K
A
G
H
G
G
T
L
D
P
K
V
S
G
V
L
P
V
A
L
E
K
A
T
R
V
V
Q
A
L
L
P
A
G
K
E
Y
V
A
L
M
H
L
-------------------
H
G
D
V
P
E
D
K
I
I
Q
V
M
K
E
F
E
G
E
I
I
Q
R
-------------
L
-----------
R
T
R
K
V
Y
Y
I
E
V
L
E
I
--------
E
G
R
D
V
L
F
R
V
G
V
E
A
G
T
Y
I
R
S
L
I
H
H
I
G
L
A
L
G
V
G
A
H
M
S
E
L
R
R
T
R
S
G
P
F
K
E
D
-
E
T
-
L
I
T
L
H
D
L
V
D
Y
Y
Y
F
W
K
-------
E
---------
D
G
----------
I
E
E
Y
F
R
K
A
I
Q
P
M
E
K
A
V
E
H
L
P
K
V
W
I
K
D
S
A
V
A
A
V
T
H
G
A
D
--
L
A
V
P
GIA
K
L
H
A
G
I
--
K
---
R
G
D
L
V
A
I
M
T
--
L
K
D
E
L
V
A
L
------------------------------------------
20
PsiBlast_PDB
76.14
32%
-131
- C6 -
3HJY
3
TRUB_PYRFU
A:
[40-292]
----
G
V
I
N
L
D
K
P
P
G
P
T
S
H
E
V
V
A
W
I
K
K
I
L
N
L
E
K
A
G
H
G
G
T
L
D
P
K
V
S
G
V
L
P
V
A
L
E
K
A
T
R
V
V
Q
A
L
L
P
A
G
K
E
Y
V
A
L
M
H
L
-------------------
H
G
D
V
P
E
D
K
I
I
Q
V
M
K
E
F
E
G
E
I
I
Q
R
P
P
L
----------
L
-----------
R
T
R
K
V
Y
Y
I
E
V
L
E
I
--------
E
G
R
D
V
L
F
R
V
G
V
E
A
G
T
Y
I
R
S
L
I
H
H
I
G
L
A
L
G
V
G
A
H
M
S
E
L
R
R
T
R
S
G
P
F
K
E
D
-
E
T
-
L
I
T
L
H
D
L
V
D
Y
Y
Y
F
W
K
-------
E
---------
D
G
----------
I
E
E
Y
F
R
K
A
I
Q
P
M
E
K
A
V
E
H
L
P
K
V
W
I
K
D
S
A
V
A
A
V
T
H
G
A
D
--
L
A
V
P
GIA
K
L
H
A
G
I
--
K
---
R
G
D
L
V
A
I
M
T
--
L
K
D
E
L
V
A
L
------------------------------------------
19
PsiBlast_PDB
75.04
32%
-121
- C6 -
3HJW
2
TRUB_PYRFU
A:
[40-292]
----
G
V
I
N
L
D
K
P
P
G
P
T
S
H
E
V
V
A
W
I
K
K
I
L
N
L
E
K
A
G
H
G
G
T
L
D
P
K
V
S
G
V
L
P
V
A
L
E
K
A
T
R
V
V
Q
A
L
L
P
A
G
K
E
Y
V
A
L
M
H
L
-------------------
H
G
D
V
P
E
D
K
I
I
Q
V
M
K
E
F
E
G
E
I
I
Q
R
P
P
L
R
S
A
V
K
---
R
R
L
-----------
R
T
R
K
V
Y
Y
I
E
V
L
E
I
--------
E
G
R
D
V
L
F
R
V
G
V
E
A
G
T
Y
I
R
S
L
I
H
H
I
G
L
A
L
G
V
G
A
H
M
S
E
L
R
R
T
R
S
G
P
F
K
E
D
-
E
T
-
L
I
T
L
H
D
L
V
D
Y
Y
Y
F
W
K
-------
E
---------
D
G
----------
I
E
E
Y
F
R
K
A
I
Q
P
M
E
K
A
V
E
H
L
P
K
V
W
I
K
D
S
A
V
A
A
V
T
H
G
A
D
--
L
A
V
P
GIA
K
L
H
A
G
I
--
K
---
R
G
D
L
V
A
I
M
T
--
L
K
D
E
L
V
A
L
------------------------------------------
13
PsiBlast_PDB
74.93
32%
-124
- C6 -
3HAY
1
TRUB_PYRFU
A:
[47-299]
----
G
V
I
N
L
D
K
P
P
G
P
T
S
H
E
V
V
A
W
I
K
K
I
L
N
L
E
K
A
G
H
G
G
T
L
D
P
K
V
S
G
V
L
P
V
A
L
E
K
A
T
R
V
V
Q
A
L
L
P
A
G
K
E
Y
V
A
L
M
H
L
-------------------
H
G
D
V
P
E
D
K
I
I
Q
V
M
K
E
F
E
G
E
I
I
Q
R
P
P
L
R
S
A
V
K
---
R
R
L
-----------
R
T
R
K
V
Y
Y
I
E
V
L
E
I
--------
E
G
R
D
V
L
F
R
V
G
V
E
A
G
T
Y
I
R
S
L
I
H
H
I
G
L
A
L
G
V
G
A
H
M
S
E
L
R
R
T
R
S
G
P
F
K
E
D
-
E
T
-
L
I
T
L
H
D
L
V
D
Y
Y
Y
F
W
K
-------
E
---------
D
G
----------
I
E
E
Y
F
R
K
A
I
Q
P
M
E
K
A
V
E
H
L
P
K
V
W
I
K
D
S
A
V
A
A
V
T
H
G
A
D
--
L
A
V
P
GIA
K
L
H
A
G
I
--
K
---
R
G
D
L
V
A
I
M
T
--
L
K
D
E
L
V
A
L
------------------------------------------
12
PsiBlast_PDB
74.75
32%
-122
- C6 -
3HAX
5
TRUB_PYRFU
A:
[47-299]
----
G
V
I
N
L
D
K
P
P
G
P
T
S
H
E
V
V
A
W
I
K
K
I
L
N
L
E
K
A
G
H
G
G
T
L
D
P
K
V
S
G
V
L
P
V
A
L
E
K
A
T
R
V
V
Q
A
L
L
P
A
G
K
E
Y
V
A
L
M
H
L
-------------------
H
G
D
V
P
E
D
K
I
I
Q
V
M
K
E
F
E
G
E
I
I
Q
R
P
P
L
R
S
A
V
K
---
R
R
L
-----------
R
T
R
K
V
Y
Y
I
E
V
L
E
I
--------
E
G
R
D
V
L
F
R
V
G
V
E
A
G
T
Y
I
R
S
L
I
H
H
I
G
L
A
L
G
V
G
A
H
M
S
E
L
R
R
T
R
S
G
P
F
K
E
D
-
E
T
-
L
I
T
L
H
D
L
V
D
Y
Y
Y
F
W
K
-------
E
---------
D
G
----------
I
E
E
Y
F
R
K
A
I
Q
P
M
E
K
A
V
E
H
L
P
K
V
W
I
K
D
S
A
V
A
A
V
T
H
G
A
D
--
L
A
V
P
GIA
K
L
H
A
G
I
--
K
---
R
G
D
L
V
A
I
M
T
--
L
K
D
E
L
V
A
L
------------------------------------------