@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu16970: (2016-06-27 )
MRILFIGDVVGSPGRDMVKEYVPKLKTKYKPHFTIINGENAAHGKGLTEKIYHSLIQSGADAITMGNHTWDKKEIFDFIDDVPNLVRPANFPEGTPGKGITYVKANGKELAVINLQGRTFLPPLDDPFLKADELIAEAAKRTPYIFIDFHAEATSEKLALGWYTDGRASAVVGTHTHVQTADNRILPKGTAYITDVGMTGPYDGILGMDRETIIKRFKTNLPVRFTVAEGKTTLSGVVIDIDDQTKKAVKIERILINDDHMFFE
Atome Classification :
(20 SA)
----.........10..-------------------......20........30........40......---------..50........60........70...-.....-80-.........90---.----..--------.-------.....100.......110.......120.---------.-----..-----....130.......---140.......150......------------.160..---.....170.......180..-------------.----------------.---.---..-190.......200.-..-.....210.......220.......230.......240.......250.......260..--------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----
M
R
I
L
F
I
GDVVGSP-------------------
G
R
D
M
V
K
E
Y
V
P
K
L
KTKYKP
H
F
T
I
I
NGENAAHGKG
L
---------
T
E
K
I
Y
H
S
L
I
QSGA
D
A
I
T
MGNHTW
D
K
K
E
-
I
F
D
F
I
-
D
--DV
P
N
LVRPAN----F----PE--------G-------TPGK
G
I
T
Y
V
KANG
K
E
L
A
V
I
N
LQGRTF-LP---------P-----LD-----D
P
F
L
K
A
D
E
L
I
A
E
A
A
---KRT
P
Y
I
F
I
D
FHAEATSE
K
L
------------
A
L
G
W
YT---DGR
A
S
A
V
V
GT
H
T
H
V
QTADNR-------------I----------------L---P---KG-T
A
Y
I
T
DVGMTGP-Y-DG-ILGM
D
R
E
T
I
I
K
R
F
KTNL
P
V
R
F
T
VAEGK
T
T
L
S
G
V
V
I
DIDDQTK
K
A
V
K
I
E
R
I
L
INDDHMFFE--------
8
PsiBlast_CBE
93.44
100%
-87
- C3 -
4B2O
3
YMDB_BACSU
D:
[1-264]
----
M
R
I
L
F
I
G
D
V
V
G
S
P
-------------------
G
R
D
M
V
K
E
Y
V
P
K
L
K
T
K
Y
K
P
H
F
T
I
I
N
G
E
N
A
A
H
G
K
G
L
---------
T
E
K
I
Y
H
S
L
I
Q
S
G
A
D
A
I
T
M
G
N
H
T
W
D
K
K
E
-
I
F
D
F
I
-
D
--
D
V
P
N
L
V
R
P
A
N
----
F
----
P
E
--------
G
-------
T
P
G
K
G
I
T
Y
V
K
A
N
G
K
E
L
A
V
I
N
L
Q
G
R
T
F
-
L
P
---------
P
-----
L
D
-----
D
P
F
L
K
A
D
E
L
I
A
E
A
A
---
K
R
T
P
Y
I
F
I
D
F
H
A
E
A
T
S
E
K
L
------------
A
L
G
W
Y
T
---
D
G
R
A
S
A
V
V
G
T
H
T
H
V
Q
T
A
D
N
R
-------------
I
----------------
L
---
P
---
K
G
-
T
A
Y
I
T
D
V
G
M
T
G
P
-
Y
-
D
G
-
I
L
G
M
D
R
E
T
I
I
K
R
F
K
T
N
L
P
V
R
F
T
V
A
E
G
K
T
T
L
S
G
V
V
I
D
I
D
D
Q
T
K
K
A
V
K
I
E
R
I
L
I
N
D
D
H
M
F
F
E
--------
10
PsiBlast_CBE
93.04
100%
-85
- C3 -
4B2O
3
YMDB_BACSU
B:
[1-264]
----
M
R
I
L
F
I
G
D
V
V
G
S
P
-------------------
G
R
D
M
V
K
E
Y
V
P
K
L
K
T
K
Y
K
P
H
F
T
I
I
N
G
E
N
A
A
H
G
K
G
L
---------
T
E
K
I
Y
H
S
L
I
Q
S
G
A
D
A
I
T
M
G
N
H
T
W
D
K
K
E
-
I
F
D
F
I
-
D
--
D
V
P
N
L
V
R
P
A
N
----
F
----
P
E
--------
G
-------
T
P
G
K
G
I
T
Y
V
K
A
N
G
K
E
L
A
V
I
N
L
Q
G
R
T
F
-
L
P
---------
P
-----
L
D
-----
D
P
F
L
K
A
D
E
L
I
A
E
A
A
---
K
R
T
P
Y
I
F
I
D
F
H
A
E
A
T
S
E
K
L
------------
A
L
G
W
Y
T
---
D
G
R
A
S
A
V
V
G
T
H
T
H
V
Q
T
A
D
N
R
-------------
I
----------------
L
---
P
---
K
G
-
T
A
Y
I
T
D
V
G
M
T
G
P
-
Y
-
D
G
-
I
L
G
M
D
R
E
T
I
I
K
R
F
K
T
N
L
P
V
R
F
T
V
A
E
G
K
T
T
L
S
G
V
V
I
D
I
D
D
Q
T
K
K
A
V
K
I
E
R
I
L
I
N
D
D
H
M
F
F
E
--------
14
HHSearch
92.66
100%
-84
- C3 -
4B2O
3
YMDB_BACSU
A:
[1-264]
----
M
R
I
L
F
I
G
D
V
V
G
S
P
-------------------
G
R
D
M
V
K
E
Y
V
P
K
L
K
T
K
Y
K
P
H
F
T
I
I
N
G
E
N
A
A
H
G
K
G
L
---------
T
E
K
I
Y
H
S
L
I
Q
S
G
A
D
A
I
T
M
G
N
H
T
W
D
K
K
E
-
I
F
D
F
I
-
D
--
D
V
P
N
L
V
R
P
A
N
----
F
----
P
E
--------
G
-------
T
P
G
K
G
I
T
Y
V
K
A
N
G
K
E
L
A
V
I
N
L
Q
G
R
T
F
-
L
P
---------
P
-----
L
D
-----
D
P
F
L
K
A
D
E
L
I
A
E
A
A
---
K
R
T
P
Y
I
F
I
D
F
H
A
E
A
T
S
E
K
L
------------
A
L
G
W
Y
T
---
D
G
R
A
S
A
V
V
G
T
H
T
H
V
Q
T
A
D
N
R
-------------
I
----------------
L
---
P
---
K
G
-
T
A
Y
I
T
D
V
G
M
T
G
P
-
Y
-
D
G
-
I
L
G
M
D
R
E
T
I
I
K
R
F
K
T
N
L
P
V
R
F
T
V
A
E
G
K
T
T
L
S
G
V
V
I
D
I
D
D
Q
T
K
K
A
V
K
I
E
R
I
L
I
N
D
D
H
M
F
F
E
--------
1
PsiBlast_PDB
92.66
100%
-84
- C3 -
4B2O
3
YMDB_BACSU
A:
[1-264]
----
M
R
I
L
F
I
G
D
V
V
G
S
P
-------------------
G
R
D
M
V
K
E
Y
V
P
K
L
K
T
K
Y
K
P
H
F
T
I
I
N
G
E
N
A
A
H
G
K
G
L
---------
T
E
K
I
Y
H
S
L
I
Q
S
G
A
D
A
I
T
M
G
N
H
T
W
D
K
K
E
-
I
F
D
F
I
-
D
--
D
V
P
N
L
V
R
P
A
N
----
F
----
P
E
--------
G
-------
T
P
G
K
G
I
T
Y
V
K
A
N
G
K
E
L
A
V
I
N
L
Q
G
R
T
F
-
L
P
---------
P
-----
L
D
-----
D
P
F
L
K
A
D
E
L
I
A
E
A
A
---
K
R
T
P
Y
I
F
I
D
F
H
A
E
A
T
S
E
K
L
------------
A
L
G
W
Y
T
---
D
G
R
A
S
A
V
V
G
T
H
T
H
V
Q
T
A
D
N
R
-------------
I
----------------
L
---
P
---
K
G
-
T
A
Y
I
T
D
V
G
M
T
G
P
-
Y
-
D
G
-
I
L
G
M
D
R
E
T
I
I
K
R
F
K
T
N
L
P
V
R
F
T
V
A
E
G
K
T
T
L
S
G
V
V
I
D
I
D
D
Q
T
K
K
A
V
K
I
E
R
I
L
I
N
D
D
H
M
F
F
E
--------
9
PsiBlast_CBE
91.82
100%
-86
- C3 -
4B2O
3
YMDB_BACSU
C:
[1-264]
----
M
R
I
L
F
I
G
D
V
V
G
S
P
-------------------
G
R
D
M
V
K
E
Y
V
P
K
L
K
T
K
Y
K
P
H
F
T
I
I
N
G
E
N
A
A
H
G
K
G
L
---------
T
E
K
I
Y
H
S
L
I
Q
S
G
A
D
A
I
T
M
G
N
H
T
W
D
K
K
E
-
I
F
D
F
I
-
D
--
D
V
P
N
L
V
R
P
A
N
----
F
----
P
E
--------
G
-------
T
P
G
K
G
I
T
Y
V
K
A
N
G
K
E
L
A
V
I
N
L
Q
G
R
T
F
-
L
P
---------
P
-----
L
D
-----
D
P
F
L
K
A
D
E
L
I
A
E
A
A
---
K
R
T
P
Y
I
F
I
D
F
H
A
E
A
T
S
E
K
L
------------
A
L
G
W
Y
T
---
D
G
R
A
S
A
V
V
G
T
H
T
H
V
Q
T
A
D
N
R
-------------
I
----------------
L
---
P
---
K
G
-
T
A
Y
I
T
D
V
G
M
T
G
P
-
Y
-
D
G
-
I
L
G
M
D
R
E
T
I
I
K
R
F
K
T
N
L
P
V
R
F
T
V
A
E
G
K
T
T
L
S
G
V
V
I
D
I
D
D
Q
T
K
K
A
V
K
I
E
R
I
L
I
N
D
D
H
M
F
F
E
--------
15
HHSearch
73.71
45%
-91
- C3 -
1T70
-
?
A:
[1-254]
----
M
R
V
L
F
I
G
D
V
F
G
Q
P
-------------------
G
R
R
V
L
Q
N
H
L
P
T
I
R
P
Q
F
--
D
F
V
I
V
N
M
E
N
S
A
G
G
F
G
M
---------
H
R
D
A
A
R
G
A
L
E
A
G
A
G
C
L
T
L
G
N
H
A
W
H
H
K
D
-
I
Y
P
M
L
-
S
E
D
T
-
Y
P
I
V
R
P
L
N
----
Y
----
A
D
P-------
G
-------
T
P
G
V
G
W
R
T
F
D
V
N
G
E
K
L
T
V
V
N
L
L
G
R
V
F
-
M
E
---------
A
-----
V
D
-----
N
P
F
R
T
M
D
A
L
L
E
R
D
-----
D
L
G
T
V
F
V
D
F
H
A
E
A
T
S
E
K
E
------------
A
M
G
W
H
L
---
A
G
R
V
A
A
V
I
G
T
H
T
H
V
P
T
A
D
T
R
-------------
I
----------------
L
---
K
---
G
G
-
T
A
Y
Q
T
D
A
G
F
T
G
P
-
H
-
D
S
-
I
I
G
S
A
I
E
G
P
L
Q
R
F
L
T
E
R
P
H
R
Y
G
V
A
E
G
R
A
E
L
N
G
V
A
L
H
F
E
--
G
G
K
A
T
A
A
E
R
Y
R
F
I
E
--------------
16
HHSearch
73.24
45%
-92
- C3 -
2Z06
3
?
A:
[1-251]
----
M
R
V
L
F
I
G
D
V
M
A
E
P
-------------------
G
L
R
A
V
G
L
H
L
P
D
I
R
D
--
R
Y
D
L
V
I
A
N
G
E
N
A
A
R
G
K
G
L
---------
D
R
R
S
Y
R
L
L
R
E
A
G
V
D
L
V
S
L
G
N
H
A
W
D
H
K
E
-
V
Y
A
L
L
-
E
--
S
-
E
P
V
V
R
P
L
N
----
Y
----
P
P
--------
G
-------
T
P
G
K
G
F
W
R
L
E
V
G
G
E
S
L
L
F
V
Q
V
M
G
R
I
F
-
M
D
---------
P
-----
L
D
-----
D
P
F
R
A
L
D
R
L
L
E
--
E
---
E
K
A
D
Y
V
L
V
E
V
H
A
E
A
T
S
E
K
M
------------
A
L
A
H
Y
L
---
D
G
R
A
S
A
V
L
G
T
H
T
H
V
P
T
L
D
A
T
-------------
R
----------------
L
---
P
---
K
G
-
T
L
Y
Q
T
D
V
G
M
T
G
T
-
Y
-
H
S
-
I
I
G
G
E
V
E
T
F
L
A
R
F
L
T
G
R
P
Q
P
F
R
A
A
Q
G
K
A
R
F
H
A
T
E
L
V
F
E
--
G
G
R
P
V
A
I
S
P
Y
V
W
E
E
--------------
4
PsiBlast_PDB
71.71
44%
-87
- C3 -
1T70
-
?
A:
[1-255]
----
M
R
V
L
F
I
G
D
V
F
G
Q
P
-------------------
G
R
R
V
L
Q
N
H
L
P
T
I
R
P
Q
F
D
--
F
V
I
V
N
M
E
N
S
A
G
G
F
G
M
---------
H
R
D
A
A
R
G
A
L
E
A
G
A
G
C
L
T
L
G
N
H
A
W
H
H
K
D
-
I
Y
P
M
L
S
E
--
D
T
Y
P
I
V
R
P
L
N
----
Y
----
A
D
P-------
G
-------
T
P
G
V
G
W
R
T
F
D
V
N
G
E
K
L
T
V
V
N
L
L
G
R
V
F
-
M
E
---------
A
-----
V
D
-----
N
P
F
R
T
M
D
A
L
L
E
R
D
D
---
L
G
T
--
V
F
V
D
F
H
A
E
A
T
S
E
K
E
------------
A
M
G
W
H
L
---
A
G
R
V
A
A
V
I
G
T
H
T
H
V
P
T
A
D
T
R
-------------
I
----------------
L
---
K
---
G
G
-
T
A
Y
Q
T
D
A
G
F
T
G
P
-
H
-
D
S
-
I
I
G
S
A
I
E
G
P
L
Q
R
F
L
T
E
R
P
H
R
Y
G
V
A
E
G
R
A
E
L
N
G
V
A
L
H
F
--
E
G
G
K
A
T
A
A
E
R
Y
R
F
I
E
D
-------------
5
PsiBlast_PDB
71.04
39%
-88
- C3 -
1T71
2
Y349_MYCPN
A:
[5-268]
----
I
K
F
I
F
L
G
D
V
Y
G
K
A
-------------------
G
R
N
I
I
K
N
N
L
A
Q
L
K
S
K
Y
Q
A
D
L
V
I
V
N
A
E
N
T
T
H
G
K
G
L
---------
S
L
K
H
Y
E
F
L
K
E
A
G
V
N
Y
I
T
M
G
N
H
T
W
F
Q
K
L
-
D
L
A
V
V
-
I
--
N
K
K
D
L
V
R
P
L
N
LDTS
F
----
A
F
--------
H
-------
N
L
G
Q
G
S
L
V
F
E
F
N
K
A
K
I
R
I
T
N
L
L
G
T
S
V
-
P
L
---------
P
-----
F
K
T
T
---
N
P
F
K
V
L
K
E
L
I
L
K
-----
R
D
C
D
L
H
I
V
D
F
H
A
E
T
T
S
E
K
N
------------
A
F
C
M
A
F
---
D
G
Y
V
T
T
I
F
G
T
H
T
H
V
P
S
A
D
L
R
-------------
I
----------------
T
---
P
---
K
G
-
S
A
Y
I
T
D
V
G
M
C
G
P
G
F
-
G
S
-
V
I
G
A
N
P
E
Q
S
I
R
L
F
C
A
G
S
R
E
H
F
E
V
S
K
C
G
A
Q
L
N
G
V
F
F
E
V
D
V
N
T
K
K
V
I
K
T
E
A
I
R
I
V
E
D
-------------
17
HHSearch
70.00
41%
-84
- C3 -
1T71
2
Y349_MYCPN
A:
[5-271]
----
I
K
F
I
F
L
G
D
V
Y
G
K
A
-------------------
G
R
N
I
I
K
N
N
L
A
Q
L
K
S
K
Y
Q
A
D
L
V
I
V
N
A
E
N
T
T
H
G
K
G
L
---------
S
L
K
H
Y
E
F
L
K
E
A
G
V
N
Y
I
T
M
G
N
H
T
W
F
Q
K
L
D
L
A
V
V
I
-
N
--
K
-
K
D
L
V
R
P
L
N
----
L
----
D
T
--------
S
FAFH---
N
L
G
Q
G
S
L
V
F
E
F
N
K
A
K
I
R
I
T
N
L
L
G
T
S
V
P
L
P
F
--------
K
-----
T
T
-----
N
P
F
K
V
L
K
E
L
I
L
K
R
-----
D
C
D
L
H
I
V
D
F
H
A
E
T
T
S
E
K
N
------------
A
F
C
M
A
F
---
D
G
Y
V
T
T
I
F
G
T
H
T
H
V
P
S
A
D
L
R
-------------
I
----------------
T
---
P
---
K
G
-
S
A
Y
I
T
D
V
G
M
C
G
P
-
G
F
G
S
-
V
I
G
A
N
P
E
Q
S
I
R
L
F
C
A
G
S
R
E
H
F
E
V
S
K
C
G
A
Q
L
N
G
V
F
F
E
V
D
V
N
T
K
K
V
I
K
T
E
A
I
R
I
V
E
D
D
P
R
----------
2
PsiBlast_PDB
67.95
49%
-90
- C3 -
2Z06
3
?
A:
[1-227]
----
M
R
V
L
F
I
G
D
V
M
A
E
P
-------------------
G
L
R
A
V
G
L
H
L
P
D
I
R
D
R
Y
D
--
L
V
I
A
N
G
E
N
A
A
R
G
K
G
L
---------
D
R
R
S
Y
R
L
L
R
E
A
G
V
D
L
V
S
L
G
N
H
A
W
D
H
K
E
-
V
Y
A
L
L
-
E
--
S
E
P
-
V
V
R
P
L
N
----
Y
----
P
P
--------
G
-------
T
P
G
K
G
F
W
R
L
E
V
G
G
E
S
L
L
F
V
Q
V
M
G
R
I
F
-
M
D
---------
P
-----
L
D
-----
D
P
F
R
A
L
D
R
L
L
E
E
-----
E
K
A
D
Y
V
L
V
E
V
H
A
E
A
T
S
E
K
M
------------
A
L
A
H
Y
L
---
D
G
R
A
S
A
V
L
G
T
H
T
H
V
P
T
L
D
A
T
-------------
R
----------------
L
---
P
---
K
G
-
T
L
Y
Q
T
D
V
G
M
T
G
T
-
Y
-
H
S
-
I
I
G
G
E
V
E
T
F
L
A
R
F
L
T
G
R
P
Q
P
F
R
A
A
Q
G
K
A
----------------------------------------
13
PsiBlast_CBE
66.54
49%
-88
- C3 -
2Z06
4
?
B:
[1-227]
----
M
R
V
L
F
I
G
D
V
M
A
E
P
-------------------
G
L
R
A
V
G
L
H
L
P
D
I
R
D
R
Y
D
--
L
V
I
A
N
G
E
N
A
A
R
G
K
G
L
---------
D
R
R
S
Y
R
L
L
R
E
A
G
V
D
L
V
S
L
G
N
H
A
W
D
H
K
E
-
V
Y
A
L
L
-
E
--
S
E
P
-
V
V
R
P
L
N
----
Y
----
P
P
--------
G
-------
T
P
G
K
G
F
W
R
L
E
V
G
G
E
S
L
L
F
V
Q
V
M
G
R
I
F
-
M
D
---------
P
-----
L
D
-----
D
P
F
R
A
L
D
R
L
L
E
E
-----
E
K
A
D
Y
V
L
V
E
V
H
A
E
A
T
S
E
K
M
------------
A
L
A
H
Y
L
---
D
G
R
A
S
A
V
L
G
T
H
T
H
V
P
T
L
D
A
T
-------------
R
----------------
L
---
P
---
K
G
-
T
L
Y
Q
T
D
V
G
M
T
G
T
-
Y
-
H
S
-
I
I
G
G
E
V
E
T
F
L
A
R
F
L
T
G
R
P
Q
P
F
R
A
A
Q
G
K
A
----------------------------------------
11
PsiBlast_CBE
65.99
49%
-84
- C3 -
2Z06
3
?
D:
[1-227]
----
M
R
V
L
F
I
G
D
V
M
A
E
P
-------------------
G
L
R
A
V
G
L
H
L
P
D
I
R
D
R
Y
D
--
L
V
I
A
N
G
E
N
A
A
R
G
K
G
L
---------
D
R
R
S
Y
R
L
L
R
E
A
G
V
D
L
V
S
L
G
N
H
A
W
D
H
K
E
-
V
Y
A
L
L
-
E
--
S
E
P
-
V
V
R
P
L
N
----
Y
----
P
P
--------
G
-------
T
P
G
K
G
F
W
R
L
E
V
G
G
E
S
L
L
F
V
Q
V
M
G
R
I
F
-
M
D
---------
P
-----
L
D
-----
D
P
F
R
A
L
D
R
L
L
E
E
-----
E
K
A
D
Y
V
L
V
E
V
H
A
E
A
T
S
E
K
M
------------
A
L
A
H
Y
L
---
D
G
R
A
S
A
V
L
G
T
H
T
H
V
P
T
L
D
A
T
-------------
R
----------------
L
---
P
---
K
G
-
T
L
Y
Q
T
D
V
G
M
T
G
T
-
Y
-
H
S
-
I
I
G
G
E
V
E
T
F
L
A
R
F
L
T
G
R
P
Q
P
F
R
A
A
Q
G
K
A
----------------------------------------
12
PsiBlast_CBE
65.82
49%
-85
- C3 -
2Z06
3
?
C:
[1-227]
----
M
R
V
L
F
I
G
D
V
M
A
E
P
-------------------
G
L
R
A
V
G
L
H
L
P
D
I
R
D
R
Y
D
--
L
V
I
A
N
G
E
N
A
A
R
G
K
G
L
---------
D
R
R
S
Y
R
L
L
R
E
A
G
V
D
L
V
S
L
G
N
H
A
W
D
H
K
E
-
V
Y
A
L
L
-
E
--
S
E
P
-
V
V
R
P
L
N
----
Y
----
P
P
--------
G
-------
T
P
G
K
G
F
W
R
L
E
V
G
G
E
S
L
L
F
V
Q
V
M
G
R
I
F
-
M
D
---------
P
-----
L
D
-----
D
P
F
R
A
L
D
R
L
L
E
E
-----
E
K
A
D
Y
V
L
V
E
V
H
A
E
A
T
S
E
K
M
------------
A
L
A
H
Y
L
---
D
G
R
A
S
A
V
L
G
T
H
T
H
V
P
T
L
D
A
T
-------------
R
----------------
L
---
P
---
K
G
-
T
L
Y
Q
T
D
V
G
M
T
G
T
-
Y
-
H
S
-
I
I
G
G
E
V
E
T
F
L
A
R
F
L
T
G
R
P
Q
P
F
R
A
A
Q
G
K
A
----------------------------------------
34
Fugue
65.43
37%
-81
- C3 -
1T71
2
Y349_MYCPN
A:
[1-281]
M
M
N
S
I
K
F
I
F
L
G
D
V
Y
G
K
A
-------------------
G
R
N
I
I
K
N
N
L
A
Q
L
K
S
K
Y
Q
A
D
L
V
I
V
N
A
E
N
T
T
H
G
K
G
L
---------
S
L
K
H
Y
E
F
L
K
E
A
G
V
N
Y
I
T
M
G
N
H
T
W
F
Q
K
L
-
D
L
A
V
V
-
I
--
N
K
K
D
L
V
R
P
L
N
----
L
DTSF
A
F
--------
H
-------
N
L
G
Q
G
S
L
V
F
E
F
N
K
A
K
I
R
I
T
N
L
L
G
T
S
V
-
P
L
---------
P
-----
F
K
-----
T
T
N
P
F
K
V
L
K
E
L
I
L
K
---
R
D
C
D
L
H
I
V
D
F
H
A
E
T
T
S
E
K
N
------------
A
F
C
M
A
F
---
D
G
Y
V
T
T
I
F
G
T
H
T
H
V
P
S
A
D
L
R
-------------
I
----------------
T
---
P
---
K
G
-
S
A
Y
I
T
D
V
G
M
C
G
P
-
G
-
F
G
S
V
I
G
A
N
P
E
Q
S
I
R
L
F
C
A
G
S
R
E
H
F
E
V
S
K
C
G
A
Q
L
N
G
V
F
F
E
V
D
V
N
T
K
K
V
I
K
T
E
A
I
R
I
V
E
D
D
P
R
Y
L
K
QDYFNLI
3
PsiBlast_PDB
65.25
48%
-84
- C3 -
2CV9
-
?
A:
[2-227]
-----
R
V
L
F
I
G
D
V
M
A
E
P
-------------------
G
L
R
A
V
G
L
H
L
P
D
I
R
D
R
Y
D
--
L
V
I
A
N
G
E
N
A
A
R
G
K
G
L
---------
D
R
R
S
Y
R
L
L
R
E
A
G
V
D
L
V
S
L
G
N
H
A
W
D
H
K
E
-
V
Y
A
L
L
-
E
--
S
E
P
-
V
V
R
P
L
N
----
Y
----
P
P
--------
G
-------
T
P
G
K
G
F
W
R
L
E
V
G
G
E
S
L
L
F
V
Q
V
M
G
R
I
F
-
M
D
---------
P
-----
L
D
-----
D
P
F
R
A
L
D
R
L
L
E
E
-----
E
K
A
D
Y
V
L
V
E
V
H
A
E
A
T
S
E
K
M
------------
A
L
A
H
Y
L
---
D
G
R
A
S
A
V
L
G
T
H
T
H
V
P
T
L
D
A
T
-------------
R
----------------
L
---
P
---
K
G
-
T
L
Y
Q
T
D
V
G
M
T
G
T
-
Y
-
H
S
-
I
I
G
G
E
V
E
T
F
L
A
R
F
L
T
G
R
P
Q
P
F
R
A
A
Q
G
K
A
----------------------------------------
21
HHSearch
55.97
15%
-120
- C3 -
2Z1A
4
?
A:
[30-289]
----
L
T
L
V
H
T
N
D
T
H
A
H
L
E
P
V
E
L
T
L
SG
E
K
T
P
V
G
----
G
V
A
R
R
V
A
L
F
D
R
V
W
A
R
A
K
N
P
L
F
L
D
A
G
D
V
F
Q
G
T
L
Y
F
N
Q
YR-----
G
L
A
D
R
Y
F
M
H
R
L
R
Y
R
A
M
A
L
G
N
H
E
F
D
L
G
P
-
G
--
P
L
------
A
D
F
L
K
G
A
R
----
F
----
K
V
V
S
ANVDA-
S
REPRLK-
G
L
F
A
P
Y
A
V
V
V
V
G
G
E
R
V
G
I
I
G
L
T
T
P
D
T
-
R
E
ISN------
P
GPT
V
A
F
L
-----
D
P
Y
E
S
A
Q
K
A
V
Y
E
L
L
A
--
K
G
V
N
K
I
V
V
L
S
H
L
G
Y
G
E
D
L
-------------
K
L
A
R
R
L
----
V
G
V
Q
V
I
V
G
G
H
S
H
T
L
L
G
S
F
P
HKELSPAGPY
P
T
-
V
----------------
V
K
N
P
E
---
G
K
-
D
V
L
V
V
Q
A
W
E
W
G
K
-
V
-
V
G
-
L
L
E
V
T
F
D
-------------------------------------------------------------
19
HHSearch
52.19
16%
-116
- C3 -
4H2G
4
5NTD_HUMAN
A:
[26-292]
----
L
T
I
L
H
T
N
D
V
H
S
R
L
EQTSEDSSKCVDASRCMG-
G
V
A
R
L
F
T
K
V
Q
Q
I
R
R
A
E
P
N
V
L
L
L
D
A
G
D
Q
Y
Q
G
T
I
W
F
T
V
YK-----
G
A
E
V
A
H
F
M
N
A
L
R
Y
D
A
M
A
L
G
N
H
E
F
D
N
G
V
-
E
G
-
L
I
------
E
P
L
L
K
E
A
K
----
F
----
P
I
L
S
AN
I
K
A
K
G
P
L
A
S
Q
I
S
G
L
Y
L
P
Y
K
V
L
P
V
G
D
E
V
V
G
I
V
G
Y
T
S
K
E
T
-
P
F
LSNPGTN
L
-
V
-----
F
E
-----
D
E
I
T
A
L
Q
P
E
V
D
K
L
K
T
--
L
N
V
N
K
I
I
A
L
G
H
S
G
F
E
M
D
-
K
------------
L
I
A
Q
K
V
----
R
G
V
D
V
V
V
G
G
H
S
N
T
F
L
Y
T
G
N
PPSKEVPAGKYPF
I
----------------
V
---
T
SDD
G
R
-
K
V
P
V
V
Q
A
Y
A
F
G
K
-
Y
-
L
G
-
Y
L
K
I
E
F
D
-------------------------------------------------------------
18
HHSearch
50.68
18%
-96
- C3 -
3ZTV
3
5NTD_HAEIN
A:
[13-280]
----
L
S
I
L
H
I
N
D
H
H
S
Y
L
E
P
H
E
T
R
I
NLNG
Q
Q
T
K
V
D
I
G
G
F
S
A
V
N
A
K
L
N
K
L
R
K
K
Y
K
N
P
L
V
L
H
A
G
D
A
I
T
G
T
L
Y
F
T
L
F
G-----
G
S
A
D
A
A
V
M
N
A
G
N
F
H
Y
F
T
L
G
N
H
E
F
D
A
G
N
-
E
--
G
L
------
L
K
L
L
E
P
L
K
----
I
----
P
V
L
S
AN
V
I
P
-
D
KSSILY-
N
K
W
K
P
Y
D
I
F
T
V
D
G
E
K
I
A
I
I
G
L
D
T
V
N
K
-
T
V
N
S
S
S
P
G
KD
V
K
-----
F
Y
-----
D
E
I
A
T
A
Q
I
M
A
N
A
L
K
Q--
Q
G
I
N
K
I
I
L
L
S
H
A
G
S
E
K
N
I
-------------
E
I
A
Q
K
V
----
N
D
I
D
V
I
V
T
G
D
S
H
Y
L
Y
G
N
D
E
-------------
L
R
S
L
KLPVIYEY
P
L
E
F
K
N
---
P
---
N
G
E
P
V
F
V
M
E
G
W
A
Y
S
A
-
V
-
V
G
-
D
L
G
V
K
F
S
-------------------------------------------------------------
20
HHSearch
50.43
16%
-100
- C3 -
4Q7F
3
?
A:
[20-279]
----
I
A
F
Y
V
V
S
D
V
H
G
Y
I
FPTDFTSRNQYQPM-----
G
L
L
L
A
N
H
V
I
E
Q
D
R
R
Q
Y
D
Q
S
F
K
I
D
N
G
D
F
L
Q
G
S
P
F
C
N
Y
L
I
A
H
SGS
S
Q
P
L
V
D
F
Y
N
R
M
A
F
D
F
G
T
L
G
N
H
E
F
N
Y
G
L
-
P
--
Y
L
------
K
D
T
L
R
R
L
N
----
Y
----
P
V
L
C
AN
I
Y
E
-
N
DST----
L
T
D
N
G
V
K
Y
F
Q
V
G
D
Q
T
V
G
V
I
G
L
T
T
Q
F
I
-
P
H
WE-------
Q
-----
P
E
HIQS
L
T
F
H
S
A
F
E
I
L
Q
Q
Y
L
P
E
M
K
R
H
A
D
I
I
V
V
C
Y
H
G
G
F
E
K
D
L
E
SGTPTEVLTGEN
E
G
Y
A
M
L
E
A
F
S
K
D
I
D
I
F
I
T
G
H
Q
H
R
Q
I
A
E
R
F
--------------------------------------
K
Q
--
T
A
V
I
Q
P
G
T
R
G
T
-
T
-
V
G
-
R
V
V
L
S
T
D
-------------------------------------------------------------